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Protein Ontology report - cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2
PR:000025749 - http://purl.obolibrary.org/obo/PR_000025749
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000025749   
  PRO namecyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 
  Synonyms
PRO-Short-label: EXACT:CDKN1B/iso:1/Phos:2
Other: RELATED:p27 phosphorylated form
  Definition"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs at a conserved Tyr residue that is major phosphoacceptor site in the Cdk-binding domain. Example: UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:DAN, PRO:JAN] 
  PRO Categorymodification 
  ParentPR:000003093 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000025749 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2, CDKN1B/iso:1/Phos:2

organism-modification


PR:000025750 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human), hCDKN1B/iso:1/Phos:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025750 hCDKN1B/iso:1/Phos:2
UniProtKB:P46527-1, Tyr-88, MOD:00048
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 in human. Phosphorylation at this site promotes subsequent Cdk2-mediated phosphorylation at Thr-187. UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:JAN]		 acts_upstream_of_or_withinGO:0051318 G1 phase PMID:17254966
enablesdecreased GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity relative to PR:000045370 hCDKN1B/iso:1/UnPhos:2 PMID:17254966
GO:0005515 protein binding with PR:P24385 B-cell lymphoma 1 protein (human) PMID:17254966
GO:0005515 protein binding with PR:P24864 CCNE PMID:17254966
GO:0005515 protein binding PMID:17254966
GO:0044877 protein-containing complex binding PMID:17254966