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PRO ID
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| PRO name | cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 |
| Synonyms | | PRO-Short-label: | EXACT: | CDKN1B/iso:1/Phos:3 | | Other: | RELATED: | p27 phosphorylated form |
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| Definition | "A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs at a conserved Tyr residue that is major phosphoacceptor site in the Cdk-binding domain, and phosphorylated by CDK2 on a Thr residue in the C-terminal region. Phosphorylation by CDK2 promotes degradation by the SCF-Skp2 ubiquitin-proteasome pathway. Example: UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA, PRO:DAN] |
| PRO Category | modification |
| Parent | PR:000003093 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form
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| Terms by PRO Category |
| Organism-Independent |
Organism-Specific |
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Number of Terms |
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Number of Terms | | Modification | 1 |
Organism-Modification |
1 | | | |
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