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Protein Ontology report - induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1
PR:000026005 -
http://purl.obolibrary.org/obo/PR_000026005
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000026005
PRO name
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
MCL1/iso:1
Definition
"An induced myeloid leukemia cell differentiation protein Mcl-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P97287-1
or a 1:1 ortholog thereof." [PRO:CNA]
PRO Category
sequence
Parent
PR:000010240
induced myeloid leukemia cell differentiation protein Mcl-1
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
1
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000026005
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1, MCL1/iso:1
organism-sequence
PR:P97287-1
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 (mouse), mMCL1/iso:1
Yes
organism-modification
PR:000026225
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 (mouse), mMCL1/iso:1/Clv:1
Yes
modification
PR:000026224
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1, MCL1/iso:1/Clv:1
organism-modification
PR:000026225
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 (mouse), mMCL1/iso:1/Clv:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000026225
mMCL1/iso:1/Clv:1
UniProtKB:P97287-1, 34-331
"An induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 in mouse. It lacks the N-terminal portion encompassing 33 amino acids. This form is generated by cleavage within the mitochondrial matrix. UniProtKB:P97287-1, 34-331." [PMID:20627101, PRO:HJD]
located_in
GO:0005759
mitochondrial matrix
MGI:4822083
;
PMID:20627101
PR:P97287-1
mMCL1/iso:1
MCL-1L (mouse)
"An induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 that is encoded in the genome of mouse." [PMID:9655929, PRO:HJD]
acts_upstream_of_or_within
GO:0008637
apoptotic mitochondrial changes
MGI:4421270
;
PMID:19919825
located_in
GO:0005739
mitochondrion
MGI:4421270
;
PMID:19919825
