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Protein Ontology report - corticotropin-releasing factor receptor 2 isoform iv-beta
PR:000026086 - http://purl.obolibrary.org/obo/PR_000026086
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000026086   
  PRO namecorticotropin-releasing factor receptor 2 isoform iv-beta 
  Synonyms
PRO-Short-label: EXACT:CRHR2/iso:iv-beta
Other: EXACT:CRF2-ivbeta
  Definition"A corticotropin-releasing factor receptor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:C0K3M3 or a 1:1 ortholog thereof. This sequence corresponds to the isoform beta with an insertion that encodes to includes a unique C-terminal cytoplasmic tail." [PRO:HJD] 
  PRO Categorysequence 
  ParentPR:000005870 corticotropin-releasing factor receptor 2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000026086 corticotropin-releasing factor receptor 2 isoform iv-beta, CRHR2/iso:iv-beta


organism-sequence



PR:C0K3M3 corticotropin-releasing factor receptor 2 isoform iv-beta (mouse), mCRHR2/iso:iv-beta

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:C0K3M3 mCRHR2/iso:iv-beta

"A corticotropin-releasing factor receptor 2 isoform iv-beta that is encoded in the genome of mouse." [PMID:7708757, PRO:HJD]
acts_upstream_of_or_withinGO:0043950 positive regulation of cAMP-mediated signaling MGI:3850921; PMID:19246489
GO:0043951 negative regulation of cAMP-mediated signaling MGI:3850921; PMID:19246489
located_inGO:0005783 endoplasmic reticulum MGI:3850921; PMID:19246489
GO:0005794 Golgi apparatus MGI:3850921; PMID:19246489
NOT GO:0009986 cell surface MGI:3850921; PMID:19246489