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Protein Ontology report - neural cell adhesion molecule L1 isoform 1, signal peptide removed phosphorylated 1 (human) PR:000026222 - http://purl.obolibrary.org/obo/PR_000026222   Ontology Information Show OBO stanza / GPI   PRO ID PR:000026222      PRO name neural cell adhesion molecule L1 isoform 1, signal peptide removed phosphorylated 1 (human)    Synonyms PRO-Short-label: EXACT: hL1CAM/iso:1/SigPep-/Phos:1 PRO-proteoform-std: EXACT: UniProtKB:P32004-1, 20-1257, Tyr-1176, MOD:00048 Other: EXACT: PRO_0000015022, Tyr-1176, MOD:00048   Definition "A neural cell adhesion molecule L1 isoform 1, signal peptide removed phosphorylated 1 in human. Tyr-1176 of the YRSLE motif is phosphorylated by SRC tyrosine kinase associated with lipid rafts in the P-domain of the growth cone. Phosphorylation of Y1176 prevents L1 binding to AP-2, an adaptor required for clathrin mediated internalization of L1. UniProtKB:P32004-1, 20-1257, Tyr-1176, MOD:00048." [PMID:12082080, PRO:CNA]    PRO Category organism-modification    Parent PR:000026192 neural cell adhesion molecule L1 isoform 1, signal peptide removed phosphorylated 1 PR:P32004 neural cell adhesion molecule L1 (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: