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RACE-PRO
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Documentation
Protein Ontology report - prelamin-A/C isoform A
PR:000026539 -
http://purl.obolibrary.org/obo/PR_000026539
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000026539
PRO name
prelamin-A/C isoform A
Synonyms
PRO-Short-label
:
EXACT:
LMNA/iso:A
Other
:
EXACT:
prelamin-A/C isoform 1
Definition
"A prelamin-A/C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P02545-1
or a 1:1 ortholog thereof." [
PMID:10080180
]
PRO Category
sequence
Parent
PR:000009859
prelamin-A/C
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000026539
prelamin-A/C isoform A, LMNA/iso:A
organism-sequence
PR:P02545-1
prelamin-A/C isoform A (human), hLMNA/iso:A
Yes
organism-sequence
PR:P48678-1
prelamin-A/C isoform A (mouse), mLMNA/iso:A
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:P02545-1
hLMNA/iso:A
"A prelamin-A/C isoform A that is encoded in the genome of human." [PMID:10080180]
acts_upstream_of_or_within
GO:0007517
muscle organ development
PMID:10080180
enables
GO:0005198
structural molecule activity
PMID:8344919
GO:0005198
structural molecule activity
PMID:8344919
GO:0005515
protein binding
PMID:10381623
located_in
GO:0005635
nuclear envelope
PMID:3453101
GO:0005638
lamin filament
PMID:10080180
GO:0005652
nuclear lamina
PMID:8344919
GO:0005882
intermediate filament
PMID:8344919
GO:0048471
perinuclear region of cytoplasm
PMID:10080180
