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Protein Ontology report - IRAK1:IRAK4:MYD88:TIRAP:activated TLR4
PR:000027219 -
http://purl.obolibrary.org/obo/PR_000027219
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000027219
PRO name
IRAK1:IRAK4:MYD88:TIRAP:activated TLR4
Synonyms
Other
:
EXACT:
IRAK1:IRAK4:MyD88:Mal:activated TLR4
Definition
"A protein-containing complex that is composed of the activated TLR4 receptor, Mal, MyD88, IRAK1 and IRAK4." [
PMID:12538665
, TLR:AMM]
Comment
Requested by=TLR.
PRO Category
complex
Parent
G0032991
protein-containing complex
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
1
Organism-Complex
3
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
complex
PR:000027219
IRAK1:IRAK4:MYD88:TIRAP:activated TLR4, mTIRAP/Phos:1
organism-complex
PR:000027220
IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse), mTIRAP/Phos:1
organism-complex
PR:000027221
pIRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse), mTIRAP/Phos:1
organism-complex
PR:000027495
pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human), hIRAK1/iso:1/Phos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000027495
hIRAK1/iso:1/Phos:1
pIRAK1:IRAK4:MyD88:Mal:activated TLR4 (human)
"An IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 in human in which the IRAK1 subunit has been phosphorylated by IRAK4." [Reactome:R-HSA-166118]
acts_upstream_of_or_within
GO:0034142
toll-like receptor 4 signaling pathway
Reactome:REACT_6894
