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Protein Ontology report - CALCA gene translation product

PR:000027222 - http://purl.obolibrary.org/obo/PR_000027222

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000027222

PRO name

CALCA gene translation product

Synonyms

PRO-Short-label:	EXACT:	CALCA
Other:	RELATED:	CALC

Definition

"A protein that is a translation product of the human CALCA gene or a 1:1 ortholog thereof." [MGI:2151253, PRO:CNA]

PRO Category

gene

Parent

PR:000000001

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	1	Organism-Gene	4
Sequence	2	Organism-Sequence	9
Modification	5	Organism-Modification	1

Term Hierarchy
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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

gene

PR:000027222 CALCA gene translation product, CALCA

organism-gene

PR:000027223 CALCA gene translation product (mouse), mCALCA

Yes

organism-sequence

PR:P70160-1 calcitonin isoform 1 (mouse), mCALCA/iso:1

Yes

organism-sequence

PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse), mCALCA/iso:CGRP1

Yes

organism-gene

PR:000030026 CALCA gene translation product (human), hCALCA

organism-seqgroup

PR:P01258 calcitonin isoforms 1/2 (human), hCALCA/iso:[1/h2]

PR:P01258-1 ,

PR:P01258-2 ,

organism-sequence

PR:P01258-1 calcitonin isoform 1 (human), hCALCA/iso:1

organism-modification

PR:000050338 procalcitonin (human), hCALCA/iso:1/SigPep-

organism-sequence

PR:P01258-2 calcitonin isoform h2 (human), hCALCA/iso:h2

organism-sequence

PR:P06881-1 calcitonin gene-related peptide 1 (human), hCALCA/iso:CGRP1

organism-gene

PR:000036869 CALCA gene translation product (rat), rCALCA

organism-sequence

PR:P01256-1 calcitonin gene-related peptide 1 (rat), rCALCA/iso:CGRP1

organism-sequence

PR:P01257-1 calcitonin isoform 1 (rat), rCALCA/iso:1

organism-gene

PR:000036870 CALCA gene translation product (chicken), chick-CALCA

organism-sequence

PR:P07660-1 calcitonin isoform 1 (chicken), chick-CALCA/iso:1

organism-sequence

PR:P10286-1 calcitonin gene-related peptide 1 (chicken), chick-CALCA/iso:CGRP1

sequence

PR:000027224 calcitonin isoform 1, CALCA/iso:1

organism-sequence

PR:P01257-1 calcitonin isoform 1 (rat), rCALCA/iso:1

organism-sequence

PR:P01258-1 calcitonin isoform 1 (human), hCALCA/iso:1

organism-modification

PR:000050338 procalcitonin (human), hCALCA/iso:1/SigPep-

organism-sequence

PR:P07660-1 calcitonin isoform 1 (chicken), chick-CALCA/iso:1

organism-sequence

PR:P70160-1 calcitonin isoform 1 (mouse), mCALCA/iso:1

Yes

modification

PR:000050333 procalcitonin, CALCA/iso:1/SigPep-

modification

PR:000050334 amino-procalcitonin, CALCA/iso:1/Clv:1

modification

PR:000050335 immature calcitonin, CALCA/iso:1/Clv:2

modification

PR:000050337 mature calcitonin, CALCA/iso:1/Clv:4

modification

PR:000050336 calcitonin carboxypeptide-I, CALCA/iso:1/Clv:3

organism-modification

PR:000050338 procalcitonin (human), hCALCA/iso:1/SigPep-

sequence

PR:000027226 calcitonin gene-related peptide 1, CALCA/iso:CGRP1

organism-sequence

PR:P01256-1 calcitonin gene-related peptide 1 (rat), rCALCA/iso:CGRP1

organism-sequence

PR:P06881-1 calcitonin gene-related peptide 1 (human), hCALCA/iso:CGRP1

organism-sequence

PR:P10286-1 calcitonin gene-related peptide 1 (chicken), chick-CALCA/iso:CGRP1

organism-sequence

PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse), mCALCA/iso:CGRP1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000027223 mCALCA	located_in	GO:0005737 cytoplasm	MGI:3028786; PMID:14765981
PR:P70160-1 mCALCA/iso:1	located_in	GO:0005615 extracellular space	MGI:3028786; PMID:14765981
PR:P70160-1 mCALCA/iso:1	located_in	GO:0005737 cytoplasm	PMID:14765981
PR:Q99JA0-1 mCALCA/iso:CGRP1	acts_upstream_of_or_within	GO:0002027 regulation of heart rate	MGI:2445452; PMID:11717154
		NOT GO:0007528 neuromuscular junction development	MGI:1345568; PMID:10532808
		NOT GO:0008217 regulation of blood pressure	MGI:1345568; PMID:10532808
		GO:0009408 response to heat	MGI:3603999; PMID:16118273
		GO:0030279 negative regulation of ossification	MGI:3653805; PMID:15537449
		GO:0031645 negative regulation of nervous system process	MGI:2445452; PMID:11717154
		GO:0045776 negative regulation of blood pressure	MGI:2445452; PMID:11717154
		GO:0045778 positive regulation of ossification	MGI:3653805; PMID:15537449
		GO:0048265 response to pain	MGI:1933070; PMID:11276224
	located_in	GO:0030424 axon	MGI:1098517; PMID:1317267
	located_in	GO:0043025 neuronal cell body	MGI:1316900; PMID:9838101