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Protein Ontology report - Toll-interacting protein isoform 1
PR:000027250 - http://purl.obolibrary.org/obo/PR_000027250
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027250   
  PRO nameToll-interacting protein isoform 1 
  Synonyms
PRO-Short-label: EXACT:TOLLIP/iso:1
  Definition"A Toll-interacting protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ06-1 or a 1:1 ortholog thereof." [PMID:10854325, PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000016528 Toll-interacting protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000027250 Toll-interacting protein isoform 1, TOLLIP/iso:1


organism-sequence



PR:Q9H0E2-1 Toll-interacting protein isoform 1 (human), hTOLLIP/iso:1


organism-sequence



PR:Q9QZ06-1 Toll-interacting protein isoform 1 (mouse), mTOLLIP/iso:1

Yes

Yes
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TOLLIP/iso:1 forms found in complexes   

TOLLIP/iso:1 Component
Complexes
PR:Q9QZ06ZDASHZ1 mTOLLIP/iso:1 PR:000027253 IRAK1:tollip complex (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9QZ06-1 mTOLLIP/iso:1
tollip.mu (mouse)
"A Toll-interacting protein isoform 1 that is encoded in the genome of mouse." [PMID:10854325, PRO:CNA]
acts_upstream_of_or_withinGO:0006954 inflammatory response PMID:10854325
GO:0034122 negative regulation of toll-like receptor signaling pathway PMID:10854325