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Protein Ontology report - apoptosis regulator Bcl-2 isoform 1 phosphorylated 3
PR:000027462 - http://purl.obolibrary.org/obo/PR_000027462
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027462   
  PRO nameapoptosis regulator Bcl-2 isoform 1 phosphorylated 3 
  Synonyms
PRO-Short-label: EXACT:BCL2/iso:1/Phos:3
  Definition"An apoptosis regulator Bcl-2 isoform 1 phosphorylated form in which the phosphorylation occurs at the three major phosphorylation sites (Thr and two conserved Ser residues) within the motif TSPLx(7-10)GPxLS, which is part of the non-structural N-terminal loop between BH4 and BH3 regions. Example: UniProtKB:P10415-1, Thr-69, MOD:00047|Ser-70/Ser-87, MOD:00046." [PMID:18570871, PMID:19029119, PRO:PD] 
  PRO Categorymodification 
  ParentPR:000003088 apoptosis regulator Bcl-2 isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000027462 apoptosis regulator Bcl-2 isoform 1 phosphorylated 3, BCL2/iso:1/Phos:3

organism-modification


PR:000027463 apoptosis regulator Bcl-2 isoform 1 phosphorylated 3 (human), hBCL2/iso:1/Phos:3
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027463 hBCL2/iso:1/Phos:3
UniProtKB:P10415-1, Thr-69, MOD:00047|Ser-70/Ser-87, MOD:00046
"An apoptosis regulator Bcl-2 isoform 1 phosphorylated 3 in human. UniProtKB:P10415-1, Thr-69, MOD:00047|Ser-70/Ser-87, MOD:00046." [PMID:18570871, PMID:19029119, PRO:PD]		 acts_upstream_of_or_withinGO:0016239 positive regulation of macroautophagy PMID:18570871; PMID:19029119
enablesNOT GO:0005515 protein binding with PR:Q14457 BECN1 PMID:18570871; PMID:19029119