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RACE-PRO
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Documentation
Protein Ontology report - apoptosis regulator Bcl-2 isoform 1 phosphorylated 3 (human)
PR:000027463 -
http://purl.obolibrary.org/obo/PR_000027463
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000027463
PRO name
apoptosis regulator Bcl-2 isoform 1 phosphorylated 3 (human)
Synonyms
PRO-Short-label
:
EXACT:
hBCL2/iso:1/Phos:3
PRO-proteoform-std
:
EXACT:
UniProtKB:P10415-1
, Thr-69,
MOD:00047
|Ser-70/Ser-87,
MOD:00046
Definition
"An apoptosis regulator Bcl-2 isoform 1 phosphorylated 3 in human.
UniProtKB:P10415-1
, Thr-69,
MOD:00047
|Ser-70/Ser-87,
MOD:00046
." [
PMID:18570871
,
PMID:19029119
, PRO:PD]
Comment
This form is involved in macroautophagy. Phosphorylated by JNK1 during cell starvation.
PRO Category
organism-modification
Parent
PR:000027462
PR:P10415
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
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Functional Annotation (PRO-centric view)
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PRO Term
GO Annotation
Evidence
PR:000027463
hBCL2/iso:1/Phos:3
UniProtKB:P10415-1, Thr-69, MOD:00047|Ser-70/Ser-87, MOD:00046
acts_upstream_of_or_within
GO:0016239
positive regulation of macroautophagy
PMID:18570871
;
PMID:19029119
enables
NOT
GO:0005515
protein binding
with
PR:Q14457
BECN1
PMID:18570871
;
PMID:19029119