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RACE-PRO
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Protein Ontology report - epidermal growth factor receptor isoform 1
PR:000027474 -
http://purl.obolibrary.org/obo/PR_000027474
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000027474
PRO name
epidermal growth factor receptor isoform 1
Synonyms
PRO-Short-label
:
EXACT:
EGFR/iso:1
Definition
"An epidermal growth factor receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P00533-1
or a 1:1 ortholog thereof." [
PMID:18789131
, PRO:CNA]
PRO Category
sequence
Parent
PR:000006933
epidermal growth factor receptor
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
2
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000027474
epidermal growth factor receptor isoform 1, EGFR/iso:1
organism-sequence
PR:P00533-1
epidermal growth factor receptor isoform 1 (human), hEGFR/iso:1
organism-modification
PR:000027477
epidermal growth factor receptor isoform 1, signal peptide removed form (human), hEGFR/iso:1/SigPep-
organism-modification
PR:000027479
epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1 (human), hEGFR/iso:1/SigPep-/Phos:1
Yes
organism-sequence
PR:Q01279-1
epidermal growth factor receptor isoform 1 (mouse), mEGFR/iso:1
modification
PR:000027476
epidermal growth factor receptor isoform 1, signal peptide removed form, EGFR/iso:1/SigPep-
modification
PR:000027478
epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1, EGFR/iso:1/SigPep-/Phos:1
organism-modification
PR:000027479
epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1 (human), hEGFR/iso:1/SigPep-/Phos:1
Yes
organism-modification
PR:000027477
epidermal growth factor receptor isoform 1, signal peptide removed form (human), hEGFR/iso:1/SigPep-
organism-modification
PR:000027479
epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1 (human), hEGFR/iso:1/SigPep-/Phos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000027479
hEGFR/iso:1/SigPep-/Phos:1
UniProtKB:P00533-1, 25-1210, Tyr-869, MOD:00048 | PRO_0000016665, Tyr-869, MOD:00048
"An epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P00533-1, 25-1210, Tyr-869, MOD:00048." [PMID:18789131, PRO:PD]
acts_upstream_of_or_within
GO:0034504
protein localization to nucleus
PMID:18789131
located_in
GO:0005634
nucleus
PMID:18789131