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Protein Ontology report - thrombospondin-1, signal peptide removed form (human)
PR:000028410 - http://purl.obolibrary.org/obo/PR_000028410
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000028410   
  PRO namethrombospondin-1, signal peptide removed form (human) 
  Synonyms
PRO-Short-label: EXACT:hTHBS1/SigPep-
PRO-proteoform-std: EXACT:UniProtKB:P07996, 19-1170
NARROW:UniProtKB:P07996-1, 19-1170
Other: NARROW:PRO_0000035842
  Definition"A thrombospondin-1, signal peptide removed form in human. Example: UniProtKB:P07996-1, 19-1170." [PRO:DNx] 
  PRO Categoryorganism-modification 
  ParentPR:000018282 thrombospondin-1, signal peptide removed form
PR:P07996 thrombospondin-1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-modification


PR:000028410 thrombospondin-1, signal peptide removed form (human), hTHBS1/SigPep-
Yes
Yes
organism-modification


PR:000026338 thrombospondin-1 isoform 1, signal peptide removed form (human), hTHBS1/iso:1/SigPep-
Yes
organism-modification


PR:000036488 thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human), hTHBS1/iso:1/SigPep-/Glyco:1
Yes
organism-modification


PR:000036489 thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human), hTHBS1/iso:1/Clv:2/Glyco:1

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hTHBS1/SigPep- forms found in complexes   

hTHBS1/SigPep- Component
 Complexes
PR:000028410 hTHBS1/SigPep- PR:000028445 integrin alphaIIbbeta3:thrombospondin 1 (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026338 hTHBS1/iso:1/SigPep-
UniProtKB:P07996-1, 19-1170 | PRO_0000035842
"A thrombospondin-1 isoform 1, signal peptide removed form in human. UniProtKB:P07996-1, 19-1170." [PRO:DNx, UniProtKB:P07996]		 enablesGO:0004866 endopeptidase inhibitor activity PMID:8751720
located_inGO:0005615 extracellular space PMID:15662972
PR:000028410 hTHBS1/SigPep-
UniProtKB:P07996, 19-1170 | UniProtKB:P07996-1, 19-1170 | PRO_0000035842
"A thrombospondin-1, signal peptide removed form in human. Example: UniProtKB:P07996-1, 19-1170." [PRO:DNx]		 located_inGO:0005615 extracellular space PMID:15662972
PR:000036488 hTHBS1/iso:1/SigPep-/Glyco:1
UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813 | PRO_0000035842, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]		 enablesGO:0005515 protein binding with PR:000028966 hTHBS1/iso:1/Clv:2 PMID:3305519
GO:0050431 transforming growth factor beta binding PMID:15342643