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Protein Ontology report - traf6:ticam1:ticam2:activated TLR4 complex
PR:000028679 - http://purl.obolibrary.org/obo/PR_000028679
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000028679   
  PRO nametraf6:ticam1:ticam2:activated TLR4 complex 
  Synonyms
Other: RELATED:activated TLR4:TRAM:TRIF:TRAF6
  Definition"A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), TICAM2, TICAM1 and TRAF6." [Reactome:R-HSA-936976] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentG0032991 protein-containing complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex2                                                  Organism-Complex 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
complex


PR:000028679 traf6:ticam1:ticam2:activated TLR4 complex, TICAM1/PhosRes+

organism-complex


PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human), TICAM1/PhosRes+
Yes
complex


PR:000028705 pUbtraf6:ticam1:ticam2:activated TLR4 complex, hIRF7/UnMod

organism-complex


PR:000035715 pUbtraf6:ticam1:ticam2:activated TLR4 complex (human), hTRAF6/K63polyUbiq:1
Yes
organism-complex


PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse), mIRF8/iso:1/SumoRes-
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000028680 TICAM1/PhosRes+
activated TLR4:TRAM:TRIF:TRAF6 (human) | traf6:trif:tram:activated TLR4 complex (human)
"A traf6:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [Reactome:R-HSA-936976]		 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6809
located_inGO:0010008 endosome membrane Reactome:REACT_25948
PR:000035710 mIRF8/iso:1/SumoRes-
traf6:trif:tram:activated TLR4 complex (mouse)
"A traf6:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of mouse." [TLR:AMM]		 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:14530355
PR:000035715 hTRAF6/K63polyUbiq:1
activated TLR4:TRIF:K63-pUb-TRAF6 (human)
"A pUbtraf6:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [PRO:DAN, Reactome:R-HSA-936965]		 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
located_inGO:0010008 endosome membrane Reactome:REACT_25867