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Protein Ontology report - phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 2 (human) PR:000028805 - http://purl.obolibrary.org/obo/PR_000028805   Ontology Information Show OBO stanza / GPI   PRO ID PR:000028805      PRO name phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 2 (human)    Synonyms PRO-Short-label: EXACT: hPTEN/iso:1/Ac:2 PRO-proteoform-std: EXACT: UniProtKB:P60484-1, Lys-125/Lys-128, MOD:00064   Definition "A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 2 in human. UniProtKB:P60484-1, Lys-125/Lys-128, MOD:00064." [PMID:16829519, PRO:PD]    Comment Note: Acetylation inhibits PTEN ability to regulate PI3K/Akt pathway and modulates cell cycle progression. Acetylase=("KAT2B"; PR:000012332; Lys-125/Lys-128).    PRO Category organism-modification    Parent PR:000028804 phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 2 PR:P60484 phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: