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Protein Ontology report - NAD-dependent protein deacetylase sirtuin-3, mitochondrial
PR:000029756 - http://purl.obolibrary.org/obo/PR_000029756
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000029756   
  PRO nameNAD-dependent protein deacetylase sirtuin-3, mitochondrial 
  Synonyms
PRO-Short-label: EXACT:SIRT3
Gene-based: RELATED:SIR2L3
Other: EXACT:regulatory protein SIR2 homolog 3 | SIR2-like protein 3
  Definition"A protein that is a translation product of the human SIRT3 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2709
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000029756 NAD-dependent protein deacetylase sirtuin-3, mitochondrial, SIRT3

organism-gene


PR:Q8R104 NAD-dependent protein deacetylase sirtuin-3 (mouse), mSIRT3

organism-sequence


PR:Q8R104-1 NAD-dependent protein deacetylase sirtuin-3 isoform 1 (mouse), mSIRT3/iso:1
Yes
organism-sequence


PR:Q8R104-2 NAD-dependent protein deacetylase sirtuin-3 isoform 2 (mouse), mSIRT3/iso:2
Yes
organism-gene


PR:Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial (human), hSIRT3

organism-sequence


PR:Q9NTG7-1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform h1 (human), hSIRT3/iso:h1

organism-sequence


PR:Q9NTG7-2 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform h2 (human), hSIRT3/iso:h2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8R104-1
mSIRT3/iso:1
Sirt3 Isoform L (mouse) | Sirt3 Isoform M1 (mouse)		 acts_upstream_of_or_withinGO:0006476 protein deacetylation MGI:4830236; PMID:19241369
enablesGO:0032041 NAD-dependent histone H3K14 deacetylase activity MGI:4830236; PMID:19241369
located_inGO:0005739 mitochondrion MGI:4830236; PMID:19241369
PR:Q8R104-2
mSIRT3/iso:2
Sirt3 Isoform M3 (mouse) | Sirt3 Isoform S (mouse)		 enablesNOT GO:0032041 NAD-dependent histone H3K14 deacetylase activity MGI:1926994; PMID:11056054
located_inGO:0005737 cytoplasm MGI:1926994; PMID:11056054