back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - catenin beta-1 isoform 1 phosphorylated 1 (human)
PR:000030192 - http://purl.obolibrary.org/obo/PR_000030192
 
    Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000030192   
  PRO namecatenin beta-1 isoform 1 phosphorylated 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hCTNNB1/iso:1/Phos:1
PRO-proteoform-std: EXACT:UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046
  Definition"A catenin beta-1 isoform 1 phosphorylated 1 in human. Phosphorylation at Ser-663 is found in many human colon cancer cells and tissues, which display a high PAK1 activity, or in response to Wnt3a stimulation. Ser-675 can be phosphorylated by either PAK1 or PKA. UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046." [PMID:22369945, PRO:IC] 
  CommentKinase=("PAK1"; PR:000035776; Ser-663/Ser-675). Kinase=("PKA"; PR:000029188; Ser-675). 
  PRO Categoryorganism-modification 
  ParentPR:000030191
PR:P35222
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000030192
hCTNNB1/iso:1/Phos:1
UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046
acts_upstream_of_or_withinGO:0016055 Wnt signaling pathway PMID:22369945
enablesincreased GO:0003713 transcription coactivator activity relative to PR:000002862 CTNNB1/iso:1/UnMod PMID:22369945