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Protein Ontology report - ceramide synthase
PR:000031743 - http://purl.obolibrary.org/obo/PR_000031743
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000031743   
  PRO nameceramide synthase 
  Synonyms
PRO-Short-label: EXACT:TLCD3B
Gene-based: RELATED:FAM57B | FP1188
Other: EXACT:protein FAM57B | TLC domain-containing protein 3B
  Definition"A protein that is a translation product of the human TLCD3B gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000031743 ceramide synthase, TLCD3B

organism-gene


PR:Q71RH2 ceramide synthase (human), hTLCD3B

organism-sequence


PR:Q71RH2-1 ceramide synthase isoform h1 (human), hTLCD3B/iso:h1

organism-sequence


PR:Q71RH2-2 ceramide synthase isoform h2 (human), hTLCD3B/iso:h2

organism-gene


PR:Q7TNV1 ceramide synthase (mouse), mFAM57B

organism-sequence


PR:Q7TNV1-1 ceramide synthase isoform 1 (mouse), mFAM57B/iso:1
Yes
organism-sequence


PR:Q7TNV1-2 ceramide synthase isoform 2 (mouse), mFAM57B/iso:2
Yes
organism-sequence


PR:Q7TNV1-3 ceramide synthase isoform 3 (mouse), mFAM57B/iso:3
Yes
sequence


PR:000037393 ceramide synthase isoform 1, FAM57B/iso:1
Yes
organism-sequence


PR:Q7TNV1-1 ceramide synthase isoform 1 (mouse), mFAM57B/iso:1
Yes
sequence


PR:000037394 ceramide synthase isoform 2, FAM57B/iso:2

organism-sequence


PR:Q7TNV1-2 ceramide synthase isoform 2 (mouse), mFAM57B/iso:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037393 FAM57B/iso:1

"A ceramide synthase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7TNV1-1 or a 1:1 ortholog thereof." [PMID:16141072, PMID:23275342, PRO:HJD]		 acts_upstream_of_or_withinGO:0008284 positive regulation of cell population proliferation MGI:4940967; PMID:19745830
GO:0043066 negative regulation of apoptotic process MGI:4940967; PMID:19745830
PR:Q7TNV1-1 mFAM57B/iso:1

"A ceramide synthase isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PMID:23275342, PRO:HJD]		 acts_upstream_of_or_withinGO:0008284 positive regulation of cell population proliferation MGI:4940967; PMID:19745830
GO:0043066 negative regulation of apoptotic process MGI:4940967; PMID:19745830
located_inGO:0005794 Golgi apparatus MGI:5490837; PMID:23275342
PR:Q7TNV1-2 mFAM57B/iso:2

"A ceramide synthase isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PRO:HJD]		 located_inGO:0005783 endoplasmic reticulum MGI:5490837; PMID:23275342
PR:Q7TNV1-3 mFAM57B/iso:3

"A ceramide synthase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7TNV1-3." [PMID:15489334, PRO:HJD]		 located_inGO:0005783 endoplasmic reticulum MGI:5490837; PMID:23275342