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Protein Ontology report - cell division cycle protein 20 homolog phosphorylated 1 (human)
PR:000035371 -
http://purl.obolibrary.org/obo/PR_000035371
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000035371
PRO name
cell division cycle protein 20 homolog phosphorylated 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hCDC20/Phos:1
PRO-proteoform-std
:
EXACT:
UniProtKB:Q12834
, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161,
MOD:00046
|Thr-157,
MOD:00047
Other
:
RELATED:
cdc20 phosphorylated (human)
Definition
"A cell division cycle protein 20 homolog phosphorylated 1 in human. This phosphorylated form occurs during mitotic splindle disruption (or with Nocodazole treatment) via BUB1 kinase activity.
UniProtKB:Q12834
, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161,
MOD:00046
|Thr-157,
MOD:00047
." [
PMID:15525512
, PRO:KER]
Comment
Kinase=("BUB1";
PR:O43683
).
PRO Category
organism-modification
Parent
PR:000035370
PR:Q12834
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000035371
hCDC20/Phos:1
UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 | cdc20 phosphorylated (human)
acts_upstream_of_or_within
increased
GO:0031577
spindle checkpoint signaling
relative to
PR:000035369
cdc20 unphosphorylated (human)
PMID:15525512
enables
decreased
GO:0004842
ubiquitin-protein transferase activity
relative to
PR:000035369
cdc20 unphosphorylated (human)
PMID:15525512
GO:0005515
protein binding
with
PR:Q13257
hMAD2L1
PMID:15525512
GO:0005515
protein binding
PMID:15525512
located_in
GO:0000776
kinetochore
PMID:15525512