Home
|
Linked Open Data
|
Browse
|
Search
|
Statistics
|
Download
RACE-PRO
PRO tracker
Community
PRO Consortium
Publications
Documentation
Protein Ontology report - mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 7 (human)
PR:000035412 -
http://purl.obolibrary.org/obo/PR_000035412
Complex
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000035412
PRO name
mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 7 (human)
Synonyms
PRO-Short-label
:
EXACT:
hBUB1/Phos:7
PRO-proteoform-std
:
EXACT:
UniProtKB:O43683
, Ser-593,
MOD:00046
|Thr-609,
MOD:00047
NARROW:
UniProtKB:O43683-1
, Ser-593,
MOD:00046
|Thr-609,
MOD:00047
Definition
"A BUB1 CDK-consensus sites phosphorylated form in human. Phosphorylation occurs during mitosis and spindle disruption (e.g. with nocodazole). Thr-609 phosphorylation is critical for interaction with PLK1. Example:
UniProtKB:O43683-1
, Ser-593,
MOD:00046
|Thr-609,
MOD:00047
." [
PMID:16760428
, PRO:KER]
Comment
Kinase=("CDK1";
PR:000003271
).
PRO Category
organism-modification
Parent
PR:000035413
PR:000037070
PR:O43683
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
Back to top
hBUB1/Phos:7
forms found in complexes
hBUB1/Phos:7
Component
Complexes
PR:000035412
hBUB1/Phos:7
PR:000035581
Back to top
Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000035412
hBUB1/Phos:7
UniProtKB:O43683, Ser-593, MOD:00046|Thr-609, MOD:00047 | UniProtKB:O43683-1, Ser-593, MOD:00046|Thr-609, MOD:00047
acts_upstream_of_or_within
GO:0034501
protein localization to kinetochore
PMID:16760428
enables
increased
GO:0005515
protein binding
with
PR:Q9NQS7
hINCENP
PMID:16760428