Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download  RACE-PRO  PRO tracker  Community  PRO Consortium  Publications  Documentation

Protein Ontology report - mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human) PR:000035432 - http://purl.obolibrary.org/obo/PR_000035432        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000035432      PRO name mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human)    Synonyms PRO-Short-label: EXACT: hBUB1B/Phos:3 PRO-proteoform-std: EXACT: UniProtKB:O60566, Thr-608, MOD:00047 NARROW: UniProtKB:O60566-1, Thr-608, MOD:00047 Other: RELATED: BUBR1 phosphorylated (human) | hBUBR1 phosphorylated   Definition "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 in human. This phosphorylated form is observed in prometaphase and in conditions of spindle depolymerization (nocodazole). Example: UniProtKB:O60566-1, Thr-608, MOD:00047." [PMID:10593653, PMID:10749118, PMID:22801780, PRO:KER]    Comment One of the articles cited mentions BUB1B (PR:O60566) as the kinase when bound to CENPE (PR:Q02224).    PRO Category organism-modification    Parent PR:000035431 PR:O60566   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000035432 hBUB1B/Phos:3 UniProtKB:O60566, Thr-608, MOD:00047 | UniProtKB:O60566-1, Thr-608, MOD:00047 | BUBR1 phosphorylated (human) | hBUBR1 phosphorylated acts_upstream_of_or_within decreased GO:0001933 negative regulation of protein phosphorylation relative to PR:000035373 hBUB1B/PhosRes- PMID:22801780 increased GO:0007059 chromosome segregation relative to PR:000035373 hBUB1B/PhosRes- PMID:22801780 increased GO:0031577 spindle checkpoint signaling relative to PR:000035373 hBUB1B/PhosRes- PMID:22801780 increased GO:0034501 protein localization to kinetochore relative to PR:000035373 hBUB1B/PhosRes- PMID:22801780 increased GO:0034501 protein localization to kinetochore relative to PR:000035373 hBUB1B/PhosRes- PMID:22801780 increased GO:0051310 metaphase chromosome alignment relative to PR:000035373 hBUB1B/PhosRes- PMID:22801780 located_in GO:0000776 kinetochore PMID:22801780