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Protein Ontology report - spindle assembly checkpoint component MAD3 phosphorylated 2 (yeast)
PR:000035503 - http://purl.obolibrary.org/obo/PR_000035503
 
    Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000035503   
  PRO namespindle assembly checkpoint component MAD3 phosphorylated 2 (yeast) 
  Synonyms
PRO-Short-label: EXACT:yMAD3/Phos:2
PRO-proteoform-std: EXACT:UniProtKB:P47074, Ser-303/Ser-337, MOD:00046
  Definition"A spindle assembly checkpoint component MAD3 phosphorylated 2 in yeast. Phosphorylation is necessary for normal response to a lack of kinetochore tension but not for response to lack of microtubule binding to kinetochores. In addition to the phosphorylation annotated, this form might also be phosphorylated on Ser-10 and Ser-486. UniProtKB:P47074, Ser-303/Ser-337, MOD:00046." [PMID:17504936, PRO:KER] 
  CommentKinase=("Ipl1"; PR:000029237). 
  PRO Categoryorganism-modification 
  ParentPR:000035502 spindle assembly checkpoint component MAD3 phosphorylated 2
PR:P47074 spindle assembly checkpoint component MAD3 (yeast)
  TaxonNCBITaxon:559292 Saccharomyces cerevisiae S288C
  Term Hierarchy
  Visualization
DAG: OLS:
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035503 yMAD3/Phos:2
UniProtKB:P47074, Ser-303/Ser-337, MOD:00046
"A spindle assembly checkpoint component MAD3 phosphorylated 2 in yeast. Phosphorylation is necessary for normal response to a lack of kinetochore tension but not for response to lack of microtubule binding to kinetochores. In addition to the phosphorylation annotated, this form might also be phosphorylated on Ser-10 and Ser-486. UniProtKB:P47074, Ser-303/Ser-337, MOD:00046." [PMID:17504936, PRO:KER]		 acts_upstream_of_or_withinincreased GO:0031577 spindle checkpoint signaling relative to PR:000035506 yMAD3 unphosphorylated PMID:17504936