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Protein Ontology report - free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex
PR:000035733 -
http://purl.obolibrary.org/obo/PR_000035733
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000035733
PRO name
free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex
Synonyms
Other
:
RELATED:
activated TLR4:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex
Definition
"A protein-containing complex that is composed of the activated TLR4 complex, ticam1, ticam2, polyubiquitinated traf6, the components of the tak 1 complex (tak1 and tab proteins) and unanchored K63-linked polyubiquitin." [
Reactome:R
-HSA-936954]
Comment
Requested by=TLR.
PRO Category
complex
Parent
G0032991
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
2
Organism-Complex
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
complex
PR:000035733
free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex, hK63polyUbiq
organism-complex
PR:000035734
free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human), hK63polyUbiq
Yes
complex
PR:000035737
free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex, hMAP3K7/Phos:1
organism-complex
PR:000035738
free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human), hMAP3K7/Phos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000035734
hK63polyUbiq
activated TLR4:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex (human)
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6809
enables
GO:0004674
protein serine/threonine kinase activity
Reactome:REACT_26036
located_in
GO:0010008
endosome membrane
Reactome:REACT_26036
PR:000035738
hMAP3K7/Phos:1
activated TLR4:TRIF:TRAF:K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human)
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6809
located_in
GO:0010008
endosome membrane
Reactome:REACT_26039