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Protein Ontology report - IRF3:XPO1 complex
PR:000036044 - http://purl.obolibrary.org/obo/PR_000036044
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000036044   
  PRO nameIRF3:XPO1 complex 
  Synonyms
Other: EXACT:IRF3-P:IRF3-P:CRM1 | RF3pIRF3pCRM1
  Definition"A protein-containing complex that is composed of a dimer of phosphorylated IRF-3 bound to exportin-1 (via recognition of the NES sequence). This binding keeps the complex in the cytoplasm." [TLR:AMM] 
  PRO Categorycomplex 
  ParentG0032991 protein-containing complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
complex



PR:000036044 IRF3:XPO1 complex, mK63polyUbiq


organism-complex



PR:000036045 IRF3:XPO1 complex (human), mK63polyUbiq

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036045 mK63polyUbiq
IRF3pIRF3pIMP4alpha human (BROAD) | IRF3pIRF3pQip1 human (BROAD)
"An IRF3:XPO1 complex whose components are encoded in the genome of human. Exportin-1 recognizes the NES sequence (ILDELLGNMVL) and maintaints IRF-3 in the cytoplasm." [PMID:10805757, TLR:AMM]
located_inGO:0005737 cytoplasm PMID:10805757