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RACE-PRO
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Documentation
Protein Ontology report - NS4A
PR:000036830 -
http://purl.obolibrary.org/obo/PR_000036830
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000036830
PRO name
NS4A
Synonyms
PRO-Short-label
:
EXACT:
DenV-NS4A
Other
:
EXACT:
Non-structural protein 4A
Definition
"A dengue virus genome polyprotein proteolytic cleavage product that is a highly hydrophobic non-structural protein encoded by the dengue virus RNA genome that associates with membranes via 4 internal hydrophobic regions which are all able to mediate membrane targeting of a cytosolic reporter protein." [
PMID:17276984
, PRO:ES]
Comment
Requested by=IDODEN.
PRO Category
modification
Parent
PR:000036818
PR:000036841
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000036830
NS4A, DenV-NS4A
organism-modification
PR:000044763
NS4A (Dengue virus 2 Thailand/NGS-C/1944), NS4A (DEN2N)
Yes
organism-modification
PR:000044764
NS4A (Dengue virus 2 Thailand/16681/84), NS4A (DEN26)
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000044763
NS4A (DEN2N)
UniProtKB:P14340, 2094-2220 | PRO_0000037966
acts_upstream_of_or_within
GO:0019079
viral genome replication
PMID:17276984
located_in
GO:0019034
viral replication complex
PMID:17276984
PR:000044764
NS4A (DEN26)
UniProtKB:P29990, 2094-2220 | PRO_0000037933
acts_upstream_of_or_within
GO:0060339
negative regulation of type I interferon-mediated signaling pathway
PMID:14612562
