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Protein Ontology report - NS4B
PR:000036833 - http://purl.obolibrary.org/obo/PR_000036833
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000036833   
  PRO nameNS4B 
  Synonyms
PRO-Short-label: EXACT:DenV-NS4B
Other: EXACT:Non-structural protein 4B
  Definition"A dengue virus genome polyprotein proteolytic cleavage product that is a highly hydrophobic transmembrane non-structural protein encoded by the dengue virus RNA genome which is, in part, responsible for the membrane arrangements leading to the formation of the viral replication complex." [PMID:22772157, PRO:ES] 
  CommentRequested by=IDODEN. 
  PRO Categorymodification 
  ParentPR:000036818 dengue virus genome polyprotein proteolytic cleavage product
PR:000036832 precursor of NS4B
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000036833 NS4B, DenV-NS4B

organism-modification


PR:000044766 NS4B (Dengue virus 2 Thailand/NGS-C/1944), NS4B (DEN2N)
Yes
organism-modification


PR:000044767 NS4B (Dengue virus 2 Thailand/16681/84), NS4B (DEN26)
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044766 NS4B (DEN2N)
UniProtKB:P14340, 2244-2491 | PRO_0000037967
"An NS4B in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 2244-2491." [PRO:DNx]		 acts_upstream_of_or_withinGO:0019079 viral genome replication PMID:21810535
located_inGO:0019034 viral replication complex PMID:21810535
PR:000044767 NS4B (DEN26)
UniProtKB:P29990, 2244-2491 | PRO_0000037934
"An NS4B in Dengue virus 2 Thailand/16681/84. UniProtKB:P29990, 2244-2491." [PRO:DNx]		 acts_upstream_of_or_withinGO:0039563 disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity PMID:14612562