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Protein Ontology report - corticotropin-releasing factor receptor
PR:000044630 - http://purl.obolibrary.org/obo/PR_000044630
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000044630   
  PRO namecorticotropin-releasing factor receptor 
  Definition"A secretin-like G-protein coupled receptor that is a translation product of the human CRHR1 or CRHR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:XQ] 
  PRO Categoryfamily 
  ParentPR:000001095
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 7                                        
         Sequence5                                                  Organism-Sequence 19                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARfam:19
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
family



PR:000044630 corticotropin-releasing factor receptor, fam:vgate_ion_chan


gene



PR:000005869 corticotropin-releasing factor receptor 1, CRHR1


organism-gene



PR:P34998 corticotropin-releasing factor receptor 1 (human), hCRHR1


organism-sequence



PR:P34998-1 corticotropin-releasing factor receptor 1 isoform hCRF-R1 (human), hCRHR1/iso:hCRF-R1


organism-sequence



PR:P34998-2 corticotropin-releasing factor receptor 1 isoform CRF-R2 (human), hCRHR1/iso:CRF-R2


organism-sequence



PR:P34998-3 corticotropin-releasing factor receptor 1 isoform hCRF-R3 (human), hCRHR1/iso:hCRF-R3


organism-sequence



PR:P34998-4 corticotropin-releasing factor receptor 1 isoform hCRF-R4 (human), hCRHR1/iso:hCRF-R4


organism-sequence



PR:P34998-5 corticotropin-releasing factor receptor 1 isoform h5 (human), hCRHR1/iso:h5


organism-modification



PR:000047066 corticotropin-releasing factor receptor 1, signal peptide removed form (human), hCRHR1/SigPep-


organism-gene



PR:P35347 corticotropin-releasing factor receptor 1 (mouse), mCRHR1


organism-sequence



PR:P35347-1 corticotropin-releasing factor receptor 1 isoform 1 (mouse), mCRHR1/iso:1


organism-gene



PR:P35353 corticotropin-releasing factor receptor 1 (rat), rCRHR1


organism-sequence



PR:P35353-1 corticotropin-releasing factor receptor 1 isoform 1 (rat), rCRHR1/iso:1


organism-gene



PR:Q90812 corticotropin-releasing factor receptor 1 (chicken), chick-CRHR1


sequence



PR:000039322 corticotropin-releasing factor receptor 1 isoform 2, CRHR1/iso:2


organism-sequence



PR:P34998-2 corticotropin-releasing factor receptor 1 isoform CRF-R2 (human), hCRHR1/iso:CRF-R2


organism-sequence



PR:P35347-1 corticotropin-releasing factor receptor 1 isoform 1 (mouse), mCRHR1/iso:1


organism-sequence



PR:P35353-1 corticotropin-releasing factor receptor 1 isoform 1 (rat), rCRHR1/iso:1


modification



PR:000019487 corticotropin-releasing factor receptor 1, signal peptide removed form, CRHR1/SigPep-


organism-modification



PR:000047066 corticotropin-releasing factor receptor 1, signal peptide removed form (human), hCRHR1/SigPep-


gene



PR:000005870 corticotropin-releasing factor receptor 2, CRHR2


organism-gene



PR:P47866 corticotropin-releasing factor receptor 2 (rat), rCRHR2


organism-sequence



PR:P47866-1 corticotropin-releasing factor receptor 2 isoform rCRF2-alpha (rat), rCRHR2/iso:rCRF2-alpha


organism-sequence



PR:P47866-2 corticotropin-releasing factor receptor 2 isoform rCRF2-beta (rat), rCRHR2/iso:rCRF2-beta


organism-gene



PR:Q13324 corticotropin-releasing factor receptor 2 (human), hCRHR2


organism-sequence



PR:Q13324-1 corticotropin-releasing factor receptor 2 isoform alpha (human), hCRHR2/iso:alpha


organism-sequence



PR:Q13324-2 corticotropin-releasing factor receptor 2 isoform beta (human), hCRHR2/iso:beta


organism-sequence



PR:Q13324-3 corticotropin-releasing factor receptor 2 isoform gamma (human), hCRHR2/iso:gamma


organism-sequence



PR:Q13324-4 corticotropin-releasing factor receptor 2 isoform D (human), hCRHR2/iso:D


organism-sequence



PR:Q13324-5 corticotropin-releasing factor receptor 2 isoform E (human), hCRHR2/iso:E


organism-sequence



PR:Q13324-6 corticotropin-releasing factor receptor 2 isoform F (human), hCRHR2/iso:F


organism-sequence



PR:Q13324-7 corticotropin-releasing factor receptor 2 isoform desQ (human), hCRHR2/iso:desQ


organism-gene



PR:Q60748 corticotropin-releasing factor receptor 2 (mouse), mCRHR2


organism-sequence



PR:C0K3M3 corticotropin-releasing factor receptor 2 isoform iv-beta (mouse), mCRHR2/iso:iv-beta

Yes

organism-sequence



PR:Q60748-1 corticotropin-releasing factor receptor 2 isoform mCRF2-alpha (mouse), mCRHR2/iso:mCRF2-alpha


organism-sequence



PR:Q60748-2 corticotropin-releasing factor receptor 2 isoform beta (mouse), mCRHR2/iso:beta

Yes

sequence



PR:000026079 corticotropin-releasing factor receptor 2 isoform alpha, CRHR2/iso:alpha


organism-sequence



PR:Q13324-1 corticotropin-releasing factor receptor 2 isoform alpha (human), hCRHR2/iso:alpha


sequence



PR:000026081 corticotropin-releasing factor receptor 2 isoform beta, CRHR2/iso:beta


organism-sequence



PR:Q13324-2 corticotropin-releasing factor receptor 2 isoform beta (human), hCRHR2/iso:beta


organism-sequence



PR:Q60748-2 corticotropin-releasing factor receptor 2 isoform beta (mouse), mCRHR2/iso:beta

Yes

sequence



PR:000026083 corticotropin-releasing factor receptor 2 isoform gamma, CRHR2/iso:gamma


organism-sequence



PR:Q13324-3 corticotropin-releasing factor receptor 2 isoform gamma (human), hCRHR2/iso:gamma


sequence



PR:000026086 corticotropin-releasing factor receptor 2 isoform iv-beta, CRHR2/iso:iv-beta


organism-sequence



PR:C0K3M3 corticotropin-releasing factor receptor 2 isoform iv-beta (mouse), mCRHR2/iso:iv-beta

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:C0K3M3
mCRHR2/iso:iv-beta
acts_upstream_of_or_withinGO:0043950 positive regulation of cAMP-mediated signaling MGI:3850921; PMID:19246489
GO:0043951 negative regulation of cAMP-mediated signaling MGI:3850921; PMID:19246489
located_inGO:0005783 endoplasmic reticulum MGI:3850921; PMID:19246489
GO:0005794 Golgi apparatus MGI:3850921; PMID:19246489
NOT GO:0009986 cell surface MGI:3850921; PMID:19246489
PR:Q60748-2
mCRHR2/iso:beta
acts_upstream_of_or_withinGO:0043950 positive regulation of cAMP-mediated signaling PMID:19246489
located_inGO:0009986 cell surface MGI:3850921; PMID:19246489