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Protein Ontology report - E3 ubiquitin-protein ligase SIAH1 isoform 1 unphosphorylated 1 (human) PR:000045369 - http://purl.obolibrary.org/obo/PR_000045369        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000045369      PRO name E3 ubiquitin-protein ligase SIAH1 isoform 1 unphosphorylated 1 (human)    Synonyms PRO-Short-label: EXACT: hSIAH1/iso:1/UnPhos:1 PRO-proteoform-std: EXACT: UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, PR:000026291   Definition "An E3 ubiquitin-protein ligase SIAH1 isoform 1 (human) that lacks phosphorylation at Tyr-100 and Tyr-126. UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, PR:000026291." [PRO:JAN]    PRO Category organism-modification    Parent PR:Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000045369 hSIAH1/iso:1/UnPhos:1 UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, PR:000026291 "An E3 ubiquitin-protein ligase SIAH1 isoform 1 (human) that lacks phosphorylation at Tyr-100 and Tyr-126. UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, PR:000026291." [PRO:JAN] acts_upstream_of_or_within GO:0043525 positive regulation of neuron apoptotic process PMID:16230351 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PMID:16230351 enables GO:0005515 protein binding with PR:Q69ZI1 Kiaa1494 PMID:16230351