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Protein Ontology report - interferon regulatory factor 3 isoform 1 phosphorylated 2 (human)
PR:000045489 - http://purl.obolibrary.org/obo/PR_000045489
 
    Complex      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:000045489   
  PRO nameinterferon regulatory factor 3 isoform 1 phosphorylated 2 (human) 
  Synonyms
PRO-Short-label: EXACT:hIRF3/iso:1/Phos:2
PRO-proteoform-std: EXACT:UniProtKB:Q14653-1, Ser-339/Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047
Other: RELATED:p-5S,T404-IRF3 (human)
  Definition"An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated in Ser-339 and Ser and Thr residues within the two phosphorylation cluster sites. A Ser-386 on the 2S site and multiple Ser and Thr residues in the 5ST site (Ser-396, Ser-498, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, Reactome:R-HSA-936418] 
  CommentNote: Reactome does not specify the precise isoform. However, it mentions that this proteoform is involved in dimerization. Based on the positions of the modified residues, and based on the position of the dimerization domain (203-385), only isoform 1 is eligible. [PRO:DAN, PMID:23824805]. 
  PRO Categoryorganism-modification 
  ParentPR:000003259
PR:Q14653
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
  Visualization
DAG: OLS:
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hIRF3/iso:1/Phos:2 forms found in complexes   

hIRF3/iso:1/Phos:2 Component
Complexes
PR:000045489 hIRF3/iso:1/Phos:2 PR:000027084