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Protein Ontology report - platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human)
PR:000049846 -
http://purl.obolibrary.org/obo/PR_000049846
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000049846
PRO name
platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human)
Synonyms
PRO-Short-label
:
EXACT:
hPDGFRB/SigPep-/Phos:2
PRO-proteoform-std
:
EXACT:
UniProtKB:P09619
, 33-1106, Tyr-857,
MOD:00048
NARROW:
UniProtKB:P09619-1
, 33-1106, Tyr-857,
MOD:00048
Definition
"A platelet-derived growth factor receptor beta (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Tyr-857 of the amino acid sequence represented by
UniProtKB:P09619-1
. Example:
UniProtKB:P09619-1
, 33-1106, Tyr-857,
MOD:00048
." [
PMID:1653029
,
PMID:9642269
, PRO:KER]
Comment
Evidence=(ECO:0000006, based on
PMID:9642269
). Evidence=(ECO:0000006, based on
PMID:1653029
). Kinase=("PDGFRB";
PR:P09619
; Tyr-857).
PRO Category
organism-modification
Parent
PR:000037070
phosphoprotein
PR:000048725
platelet-derived growth factor receptor beta, signal peptide removed form (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000049846
hPDGFRB/SigPep-/Phos:2
UniProtKB:P09619, 33-1106, Tyr-857, MOD:00048 | UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048
"A platelet-derived growth factor receptor beta (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Tyr-857 of the amino acid sequence represented by UniProtKB:P09619-1. Example: UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048." [PMID:1653029, PMID:9642269, PRO:KER]
acts_upstream_of_or_within
increased
GO:0018108
peptidyl-tyrosine phosphorylation
relative to
PR:000049848
hPDGFRB/SigPep-/UnPhos:2
PMID:1653029
;
PMID:9642269
enables
GO:0004713
protein tyrosine kinase activity
PMID:15994317
;
PMID:9642269
increased
GO:0005515
protein binding
relative to
PR:000049848
hPDGFRB/SigPep-/UnPhos:2
PMID:1653029