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Protein Ontology report - epidermal growth factor receptor, signal peptide removed phosphorylated 4 (human)
PR:000049851 -
http://purl.obolibrary.org/obo/PR_000049851
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000049851
PRO name
epidermal growth factor receptor, signal peptide removed phosphorylated 4 (human)
Synonyms
PRO-Short-label
:
EXACT:
hEGFR/SigPep-/Phos:4
PRO-proteoform-std
:
EXACT:
UniProtKB:P00533
, 25-1210, Ser-768,
MOD:00046
NARROW:
UniProtKB:P00533-1
, 25-1210, Ser-768,
MOD:00046
Definition
"An epidermal growth factor receptor, signal peptide removed form (human) that has been phosphorylated on the residue at the position equivalent to Ser-768 of the amino acid sequence represented by
UniProtKB:P00533-1
. Example:
UniProtKB:P00533-1
, 25-1210, Ser-768,
MOD:00046
." [
PMID:10347170
, PRO:KER]
Comment
Note: The indicated residue is located within sub-kinase domain III. Evidence=(ECO:0000006, based on
PMID:10347170
). Kinase=("CAMKII";
PR:000003197
; Ser-768).
PRO Category
organism-modification
Parent
PR:000028422
epidermal growth factor receptor, signal peptide removed form (human)
PR:000037070
phosphoprotein
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
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Functional Annotation (PRO-centric view)
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PRO Term
GO Annotation
Evidence
PR:000049851
hEGFR/SigPep-/Phos:4
UniProtKB:P00533, 25-1210, Ser-768, MOD:00046 | UniProtKB:P00533-1, 25-1210, Ser-768, MOD:00046
"An epidermal growth factor receptor, signal peptide removed form (human) that has been phosphorylated on the residue at the position equivalent to Ser-768 of the amino acid sequence represented by UniProtKB:P00533-1. Example: UniProtKB:P00533-1, 25-1210, Ser-768, MOD:00046." [PMID:10347170, PRO:KER]
enables
decreased
GO:0004713
protein tyrosine kinase activity
relative to
PR:000049852
hEGFR/SigPep-/UnPhos:4
PMID:10347170
