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Protein Ontology report - protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
PR:000049853 -
http://purl.obolibrary.org/obo/PR_000049853
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000049853
PRO name
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hPRKCB/iso:Beta-II/InitMet-/Phos:1
PRO-proteoform-std
:
EXACT:
UniProtKB:P05771-2
, 2-673, Thr-500,
MOD:00047
Definition
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500.
UniProtKB:P05771-2
, 2-673, Thr-500,
MOD:00047
." [
PMID:8749392
, PRO:KER]
Comment
Evidence=(ECO:0000006, based on
PMID:8749392
).
PRO Category
organism-modification
Parent
PR:000037070
phosphoprotein
PR:000048913
protein kinase C beta type, initiator methionine removed form (human)
PR:P05771
protein kinase C beta type (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
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Functional Annotation (PRO-centric view)
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PRO Term
GO Annotation
Evidence
PR:000049853
hPRKCB/iso:Beta-II/InitMet-/Phos:1
UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047." [PMID:8749392, PRO:KER]
enables
increased
GO:0004674
protein serine/threonine kinase activity
relative to
PR:000049854
hPRKCB/iso:Beta-II/InitMet-/UnPhos:1
PMID:8749392
located_in
GO:0005737
cytoplasm
PMID:9756933
GO:0005886
plasma membrane
PMID:9756933
