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Protein Ontology report - profilin
PR:000050050 - http://purl.obolibrary.org/obo/PR_000050050
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000050050   
  PRO nameprofilin 
  Synonyms
PRO-Short-label: EXACT:fam:PFN
  Definition"A protein that is a translation product of the human PFN1, PFN2, PFN3, or PFN4 genes, or 1:1 orthologs thereof." [PRO:DAN] 
  CommentRequested by=CRAFT. 
  PRO Categoryfamily 
  ParentPR:000000001
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene4                                                  Organism-Gene 15                                        
         Sequence5                                                  Organism-Sequence 14                                        
         Modification3                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000050050 profilin, fam:PFN

gene


PR:000012585 profilin-1, PFN1

organism-gene


PR:P07737 profilin-1 (human), hPFN1

organism-sequence


PR:P07737-1 profilin-1 isoform 1 (human), hPFN1/iso:1
Yes
organism-modification


PR:000048752 profilin-1, initiator methionine removed form (human), hPFN1/InitMet-

organism-modification


PR:000068365 profilin-1 deaminated 1 (human), hPFN1/Deam:1

organism-modification


PR:000081709 profilin-1 methylated 1 (human), hPFN1/Me:1

organism-modification


PR:000083329 profilin-1 cysteinylated 1 (human), hPFN1/Cyst:1

organism-gene


PR:P62962 profilin-1 (mouse), mPFN1

organism-sequence


PR:P62962-1 profilin-1 isoform 1 (mouse), mPFN1/iso:1

organism-gene


PR:P62963 profilin-1 (rat), rPFN1

sequence


PR:000025644 profilin-1 isoform 1, PFN1/iso:1

organism-sequence


PR:P07737-1 profilin-1 isoform 1 (human), hPFN1/iso:1
Yes
organism-sequence


PR:P62962-1 profilin-1 isoform 1 (mouse), mPFN1/iso:1

modification


PR:000026622 profilin-1 isoform 1, initiator methionine removed form, PFN1/iso:1/InitMet-

modification


PR:000020937 profilin-1, initiator methionine removed form, PFN1/InitMet-

modification


PR:000026622 profilin-1 isoform 1, initiator methionine removed form, PFN1/iso:1/InitMet-

organism-modification


PR:000048752 profilin-1, initiator methionine removed form (human), hPFN1/InitMet-

gene


PR:000012586 profilin-2, PFN2

organism-gene


PR:P35080 profilin-2 (human), hPFN2

organism-sequence


PR:P35080-1 profilin-2 isoform 1 (human), hPFN2/iso:1

organism-sequence


PR:P35080-2 profilin-2 isoform 2 (human), hPFN2/iso:2

organism-gene


PR:Q9EPC6 profilin-2 (rat), rPFN2

organism-sequence


PR:Q9EPC6-1 profilin-2 isoform IIa (rat), rPFN2/iso:IIa

organism-sequence


PR:Q9EPC6-2 profilin-2 isoform IIb (rat), rPFN2/iso:IIb

organism-gene


PR:Q9JJV2 profilin-2 (mouse), mPFN2

organism-sequence


PR:Q9JJV2-1 profilin-2 isoform 1 (mouse), mPFN2/iso:1
Yes
organism-sequence


PR:Q9JJV2-2 profilin-2 isoform 2 (mouse), mPFN2/iso:2

organism-sequence


PR:Q9JJV2-3 profilin-2 isoform m3 (mouse), mPFN2/iso:m3

sequence


PR:000037455 profilin-2 isoform 1, PFN2/iso:1

organism-sequence


PR:P35080-1 profilin-2 isoform 1 (human), hPFN2/iso:1

organism-sequence


PR:Q9JJV2-1 profilin-2 isoform 1 (mouse), mPFN2/iso:1
Yes
sequence


PR:000037456 profilin-2 isoform 2, PFN2/iso:2

organism-sequence


PR:P35080-2 profilin-2 isoform 2 (human), hPFN2/iso:2

organism-sequence


PR:Q9JJV2-2 profilin-2 isoform 2 (mouse), mPFN2/iso:2

modification


PR:000020938 profilin-2, initiator methionine removed form, PFN2/InitMet-

gene


PR:000012587 profilin-3, PFN3

organism-gene


PR:M0RCP6 profilin-3 (rat), rPFN3

organism-gene


PR:P60673 profilin-3 (human), hPFN3

organism-sequence


PR:P60673-1 profilin-3 isoform 1 (human), hPFN3/iso:1

organism-gene


PR:Q9DAD6 profilin-3 (mouse), mPFN3

organism-sequence


PR:Q9DAD6-1 profilin-3 isoform 1 (mouse), mPFN3/iso:1

sequence


PR:000039893 profilin-3 isoform 1, PFN3/iso:1

organism-sequence


PR:P60673-1 profilin-3 isoform 1 (human), hPFN3/iso:1

organism-sequence


PR:Q9DAD6-1 profilin-3 isoform 1 (mouse), mPFN3/iso:1

gene


PR:000012588 profilin-4, PFN4

organism-gene


PR:P07274 profilin (yeast), yPFN4

organism-gene


PR:P39825 profilin (Schizosaccharomyces pombe 972h-), Spom972h-PFN4

organism-gene


PR:Q5IRJ7 profilin-4 (rat), rPFN4

organism-sequence


PR:Q5IRJ7-1 profilin-4 isoform 1 (rat), rPFN4/iso:1

organism-gene


PR:Q8NHR9 profilin-4 (human), hPFN4

organism-sequence


PR:Q8NHR9-1 profilin-4 isoform 1 (human), hPFN4/iso:1

organism-gene


PR:Q8T8M2 profilin-3 (Dictyostelium discoideum), Dicty-profilin3

organism-gene


PR:Q9D6I3 profilin-4 (mouse), mPFN4

organism-sequence


PR:Q9D6I3-1 profilin-4 isoform 1 (mouse), mPFN4/iso:1

sequence


PR:000041987 profilin-4 isoform 1, PFN4/iso:1

organism-sequence


PR:Q5IRJ7-1 profilin-4 isoform 1 (rat), rPFN4/iso:1

organism-sequence


PR:Q8NHR9-1 profilin-4 isoform 1 (human), hPFN4/iso:1

organism-sequence


PR:Q9D6I3-1 profilin-4 isoform 1 (mouse), mPFN4/iso:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P07737-1
hPFN1/iso:1
 located_inCHEBI:59163 biomarker PMID:18829504
PR:Q9JJV2-1
mPFN2/iso:1
profilin-2 isoform IIa (mouse)		 acts_upstream_of_or_withinGO:0030837 negative regulation of actin filament polymerization MGI:4844066; PMID:18001770
located_inGO:0043195 terminal bouton MGI:3714870; PMID:17541406