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Protein Ontology report - mothers against decapentaplegic homolog 7 (human)
PR:O15105 -
http://purl.obolibrary.org/obo/PR_O15105
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:O15105
PRO name
mothers against decapentaplegic homolog 7 (human)
Synonyms
PRO-Short-label
:
EXACT:
hSMAD7
Gene-based
:
RELATED:
MADH7 | MADH8 | SMAD7
Other
:
EXACT:
MAD homolog 7 (human) | MAD homolog 8 (human) | mothers against decapentaplegic homolog 8 (human) | mothers against DPP homolog 7 (human) | mothers against DPP homolog 8 (human) | SMAD 7 (human) | SMAD family member 7 (human) | Smad7 (human)
Definition
"A smad7 that is encoded in the genome of human." []
PRO Category
organism-gene
Parent
PR:000000374
smad7
PR:000029067
Homo sapiens protein
Gene Template
HGNC:6773
SMAD7 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
3
Modification
0
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:O15105
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:O15105
mothers against decapentaplegic homolog 7 (human), hSMAD7
organism-sequence
PR:O15105-1
mothers against decapentaplegic homolog 7 isoform 1 (human), hSMAD7/iso:1
Yes
organism-modification
PR:000036565
smad7 isoform 1 acetylated 1 (human), hSMAD7/iso:1/Ac:1
Yes
organism-modification
PR:000036566
smad7 isoform 1 phosphorylated 1 (human), hSMAD7/iso:1/Phos:1
organism-sequence
PR:O15105-2
mothers against decapentaplegic homolog 7 isoform h2 (human), hSMAD7/iso:h2
organism-sequence
PR:O15105-3
mothers against decapentaplegic homolog 7 isoform 3 (human), hSMAD7/iso:3
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036565
hSMAD7/iso:1/Ac:1
UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064
"A smad7 isoform 1 acetylated 1 in human. UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064." [PMID:12408818, PRO:CNA]
acts_upstream_of_or_within
GO:0007179
transforming growth factor beta receptor signaling pathway
PMID:12408818
enables
GO:0140416
transcription regulator inhibitor activity
PMID:12408818
located_in
GO:0005634
nucleus
PMID:11278814
PR:O15105-1
hSMAD7/iso:1
"A smad7 isoform 1 that is encoded in the genome of human." [PRO:CNA]
acts_upstream_of_or_within
GO:0006950
response to stress
PMID:9256479
GO:0007179
transforming growth factor beta receptor signaling pathway
PMID:10823886
;
PMID:9215638
enables
GO:0005515
protein binding
PMID:9256479
GO:0140416
transcription regulator inhibitor activity
PMID:9215638
located_in
GO:0005634
nucleus
PMID:11278814