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Protein Ontology report - tumor necrosis factor isoform 1 (human)
PR:P01375-1 - http://purl.obolibrary.org/obo/PR_P01375-1
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P01375-1   
  PRO nametumor necrosis factor isoform 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hTNF/iso:1
  Definition"A tumor necrosis factor isoform 1 that is encoded in the genome of human." [PRO:CNA] 
  PRO Categoryorganism-sequence 
  ParentPR:000000381 tumor necrosis factor isoform 1
PR:P01375 tumor necrosis factor (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P01375-1
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-sequence


PR:P01375-1 tumor necrosis factor isoform 1 (human), hTNF/iso:1
Yes
organism-modification


PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human), hTNF/iso:1/Clv:1
Yes
organism-modification


PR:000036507 tumor necrosis factor isoform 1 myristoylated 1 (human), hTNF/iso:1/Myr:1
Yes
organism-modification


PR:000036508 tumor necrosis factor isoform 1 phosphorylated 1 (human), hTNF/iso:1/Phos:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036504 hTNF/iso:1/Clv:1
UniProtKB:P01375-1, 77-233 | PRO_0000034424
"A tumor necrosis factor isoform 1 cleaved 1 in human. UniProtKB:P01375-1, 77-233." [PMID:14512626, PMID:3856324, PRO:CNA]		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:3856324
enablesGO:0005164 tumor necrosis factor receptor binding with PR:P19438 CD120a (human) PMID:14512626
GO:0042802 identical protein binding PMID:14512626
PR:000036507 hTNF/iso:1/Myr:1
UniProtKB:P01375-1, Lys-19/Lys-20, MOD:00087
"A tumor necrosis factor isoform 1 myristoylated 1 in human. UniProtKB:P01375-1, Lys-19/Lys-20, MOD:00087." [PMID:1402651, PRO:CNA]		 located_inGO:0016020 membrane PMID:1402651
PR:000036508 hTNF/iso:1/Phos:1
UniProtKB:P01375-1, Ser-2, MOD:00046
"A tumor necrosis factor isoform 1 phosphorylated 1 in human. UniProtKB:P01375-1, Ser-2, MOD:00046." [PMID:10205166, PMID:8597870, PRO:CNA]		 located_inGO:0016020 membrane PMID:10205166
PR:P01375-1 hTNF/iso:1

"A tumor necrosis factor isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:3856324
located_inGO:0005886 plasma membrane PMID:3349526