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Protein Ontology report - platelet-derived growth factor receptor beta (human)
PR:P09619 -
http://purl.obolibrary.org/obo/PR_P09619
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:P09619
PRO name
platelet-derived growth factor receptor beta (human)
Synonyms
PRO-Short-label
:
EXACT:
hPDGFRB
Gene-based
:
RELATED:
PDGFR | PDGFR1 | PDGFRB
Other
:
EXACT:
beta platelet-derived growth factor receptor (human) | beta-type platelet-derived growth factor receptor (human) | CD140 antigen-like family member B (human) | CD140b (human) | PDGF-R-beta (human) | PDGFR-1 (human) | PDGFR-beta (human) | platelet-derived growth factor receptor 1 (human)
Definition
"A beta-type platelet-derived growth factor receptor that is encoded in the genome of human." [PRO:WCB,
UniProtKB:P09619
]
PRO Category
organism-gene
Parent
PR:000002035
PR:000029067
Gene Template
HGNC:8804
PDGFRB (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
2
Modification
0
Organism-Modification
6
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P09619
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:P09619
platelet-derived growth factor receptor beta (human), hPDGFRB
organism-sequence
PR:P09619-1
platelet-derived growth factor receptor beta isoform 1 (human), hPDGFRB/iso:1
organism-sequence
PR:P09619-2
platelet-derived growth factor receptor beta isoform h2 (human), hPDGFRB/iso:h2
organism-modification
PR:000048725
platelet-derived growth factor receptor beta, signal peptide removed form (human), hPDGFRB/SigPep-
organism-modification
PR:000048726
platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 1 (human), hPDGFRB/SigPep-/Phos:1
organism-modification
PR:000049846
platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human), hPDGFRB/SigPep-/Phos:2
Yes
organism-modification
PR:000049847
platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human), hPDGFRB/SigPep-/Phos:3
Yes
organism-modification
PR:000049848
platelet-derived growth factor receptor beta, signal peptide removed unphosphorylated 2 (human), hPDGFRB/SigPep-/UnPhos:2
Yes
organism-modification
PR:000064602
platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 4 (human), hPDGFRB/SigPep-/Phos:4
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000049846
hPDGFRB/SigPep-/Phos:2
UniProtKB:P09619, 33-1106, Tyr-857, MOD:00048 | UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048
acts_upstream_of_or_within
increased
GO:0018108
peptidyl-tyrosine phosphorylation
relative to
PR:000049848
hPDGFRB/SigPep-/UnPhos:2
PMID:1653029
;
PMID:9642269
enables
GO:0004713
protein tyrosine kinase activity
PMID:15994317
;
PMID:9642269
increased
GO:0005515
protein binding
relative to
PR:000049848
hPDGFRB/SigPep-/UnPhos:2
PMID:1653029
PR:000049847
hPDGFRB/SigPep-/Phos:3
UniProtKB:P09619, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046 | UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046
acts_upstream_of_or_within
decreased
GO:0051897
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
relative to
PR:000049846
hPDGFRB/SigPep-/Phos:2
PMID:15271984
enables
decreased
GO:0004713
protein tyrosine kinase activity
relative to
PR:000049846
hPDGFRB/SigPep-/Phos:2
PMID:15271984
decreased
GO:0005515
protein binding
relative to
PR:000049846
hPDGFRB/SigPep-/Phos:2
PMID:15271984
PR:000049848
hPDGFRB/SigPep-/UnPhos:2
UniProtKB:P09619, 33-1106, Tyr-857, PR:000026291 | UniProtKB:P09619-1, 33-1106, Tyr-857, PR:000026291
acts_upstream_of_or_within
GO:0038083
peptidyl-tyrosine autophosphorylation
PMID:9642269