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Protein Ontology report - mitogen-activated protein kinase 1 (human)
PR:P28482 - http://purl.obolibrary.org/obo/PR_P28482
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P28482   
  PRO namemitogen-activated protein kinase 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hMAPK1
Gene-based: RELATED:ERK2 | MAPK1 | PRKM1 | PRKM2
Other: EXACT:ERK-2 (human) | ERT1 (human) | extracellular signal-regulated kinase 2 (human) | MAP kinase 1 (human) | MAP kinase 2 (human) | MAP kinase isoform p42 (human) | MAPK 1 (human) | MAPK 2 (human) | mitogen-activated protein kinase 2 (human) | p42-MAPK (human)
  Definition"A mitogen-activated protein kinase 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P28482] 
  PRO Categoryorganism-gene 
  ParentPR:000000103
PR:000029067
  Gene TemplateHGNC:6871 MAPK1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 17                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P28482
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P28482 mitogen-activated protein kinase 1 (human), hMAPK1

organism-sequence


PR:P28482-1 mitogen-activated protein kinase 1 isoform 1 (human), hMAPK1/iso:1
Yes
organism-modification


PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human), hMAPK1/iso:1/Phos:1
Yes
organism-sequence


PR:P28482-2 mitogen-activated protein kinase 1 isoform h2 (human), hMAPK1/iso:h2

organism-modification


PR:000045734 mitogen-activated protein kinase 1 phosphorylated 1 (human), hMAPK1/Phos:1

organism-modification


PR:000048313 mitogen-activated protein kinase 1, initiator methionine removed form (human), hMAPK1/InitMet-

organism-modification


PR:000048314 mitogen-activated protein kinase 1, initiator methionine removed phosphorylated 1 (human), hMAPK1/InitMet-/Phos:1

organism-modification


PR:000060366 mitogen-activated protein kinase 1 sequence variant D321V, initiator methionine removed phosphorylated 1 (human), hMAPK1/var:D321V/InitMet-/Phos:1

organism-modification


PR:000060482 mitogen-activated protein kinase 1 sequence variant E322K, initiator methionine removed phosphorylated 1 (human), hMAPK1/var:E322K/InitMet-/Phos:1

organism-modification


PR:000061403 mitogen-activated protein kinase 1 sequence variant P58G, initiator methionine removed phosphorylated 1 (human), hMAPK1/var:P58G/InitMet-/Phos:1

organism-modification


PR:000061840 mitogen-activated protein kinase 1 sequence variant E81K, initiator methionine removed phosphorylated 1 (human), hMAPK1/var:E81K/InitMet-/Phos:1

organism-modification


PR:000062009 mitogen-activated protein kinase 1 sequence variant E322V, initiator methionine removed phosphorylated 1 (human), hMAPK1/var:E322V/InitMet-/Phos:1

organism-modification


PR:000062395 mitogen-activated protein kinase 1, initiator methionine removed phosphorylated 2 (human), hMAPK1/InitMet-/Phos:2

organism-modification


PR:000062794 mitogen-activated protein kinase 1 sequence variant D321N, initiator methionine removed phosphorylated 1 (human), hMAPK1/var:D321N/InitMet-/Phos:1

organism-modification


PR:000062965 mitogen-activated protein kinase 1 sequence variant P58L, initiator methionine removed phosphorylated 1 (human), hMAPK1/var:P58L/InitMet-/Phos:1

organism-modification


PR:000063285 mitogen-activated protein kinase 1 sequence variant S142L, initiator methionine removed phosphorylated 1 (human), hMAPK1/var:S142L/InitMet-/Phos:1

organism-modification


PR:000063321 mitogen-activated protein kinase 1 sequence variant E322A, initiator methionine removed phosphorylated 1 (human), hMAPK1/var:E322A/InitMet-/Phos:1

organism-modification


PR:000083225 mitogen-activated protein kinase 1 cysteinylated 1 (human), hMAPK1/Cyst:1

organism-modification


PR:000083581 mitogen-activated protein kinase 1 methylated 1 (human), hMAPK1/Me:1

organism-modification


PR:000084106 mitogen-activated protein kinase 1 methylated 2 (human), hMAPK1/Me:2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026341
hMAPK1/iso:1/Phos:1
UniProtKB:P28482-1, Thr-185, MOD:00047|Tyr-187, MOD:00048		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:10958679
GO:0006935 chemotaxis PMID:10706854
GO:0007165 signal transduction PMID:1540184
enablesGO:0004672 protein kinase activity PMID:10706854
GO:0004707 MAP kinase activity PMID:10706854
GO:0005515 protein binding PMID:16291755
PR:P28482-1
hMAPK1/iso:1
 acts_upstream_of_or_withinGO:0006935 chemotaxis PMID:10706854
GO:0006950 response to stress PMID:10958679
GO:0007268 chemical synaptic transmission PMID:10706854
enablesNOT GO:0004707 MAP kinase activity PMID:10706854