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Protein Ontology report - natural resistance-associated macrophage protein 2 (mouse)
PR:P49282 - http://purl.obolibrary.org/obo/PR_P49282
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P49282   
  PRO namenatural resistance-associated macrophage protein 2 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mSLC11A2
Gene-based: RELATED:Dct1 | Dmt1 | Nramp2 | Slc11a2
Other: EXACT:divalent cation transporter 1 (mouse) | divalent metal transporter 1 (mouse) | DMT-1 (mouse) | NRAMP 2 (mouse) | solute carrier family 11 member 2 (mouse)
  Definition"A natural resistance-associated macrophage protein 2 that is encoded in the genome of mouse." [OMA:P49282, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000002993 natural resistance-associated macrophage protein 2
PR:000029032 Mus musculus protein
  Gene TemplateMGI:1345279 Slc11a2 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P49282
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P49282 natural resistance-associated macrophage protein 2 (mouse), mSLC11A2
Yes
organism-sequence


PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse), mSLC11A2/iso:2
Yes
organism-sequence


PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse), mSLC11A2/iso:1
Yes
organism-sequence


PR:P49282-3 natural resistance-associated macrophage protein 2 isoform m3 (mouse), mSLC11A2/iso:m3

organism-sequence


PR:P49282-4 natural resistance-associated macrophage protein 2 isoform m4 (mouse), mSLC11A2/iso:m4

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P49282 mSLC11A2
Dct1 | Dmt1 | Nramp2 | Slc11a2 | divalent cation transporter 1 (mouse) | divalent metal transporter 1 (mouse) | DMT-1 (mouse) | NRAMP 2 (mouse) | solute carrier family 11 member 2 (mouse)
"A natural resistance-associated macrophage protein 2 that is encoded in the genome of mouse." [OMA:P49282, PRO:DNx]		 acts_upstream_of_or_withinGO:0006778 porphyrin-containing compound metabolic process PMID:4404581
GO:0006826 iron ion transport PMID:807277
GO:0007611 learning or memory PMID:19211831
GO:0048813 dendrite morphogenesis PMID:19211831
GO:0048821 erythrocyte development PMID:15849611
GO:0060586 multicellular organismal-level iron ion homeostasis PMID:5070129
PR:P49282-1 mSLC11A2/iso:2
natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse)
"A natural resistance-associated macrophage protein 2 isoform 2 that is encoded in the genome of mouse." [PRO:HJD]		 acts_upstream_of_or_withinGO:0006824 cobalt ion transport MGI:3849744; PMID:10942769
GO:0006824 cobalt ion transport MGI:3849744; PMID:10942769
GO:0006824 cobalt ion transport MGI:3849744; PMID:10942769
GO:0006826 iron ion transport MGI:3849744; PMID:10942769
GO:0006826 iron ion transport MGI:3849744; PMID:10942769
GO:1902600 proton transmembrane transport MGI:3037617; PMID:15024413
enablesGO:0015078 proton transmembrane transporter activity MGI:3037617; PMID:15024413
GO:0015087 cobalt ion transmembrane transporter activity MGI:3849744; PMID:10942769
GO:0015087 cobalt ion transmembrane transporter activity MGI:3849744; PMID:10942769
GO:0015093 ferrous iron transmembrane transporter activity MGI:3849744; PMID:10942769
GO:0015093 ferrous iron transmembrane transporter activity MGI:3849744; PMID:10942769
located_inGO:0005886 plasma membrane MGI:3849744; PMID:10942769
GO:0005886 plasma membrane MGI:3849744; PMID:10942769
GO:0005886 plasma membrane MGI:3849744; PMID:10942769
GO:0009986 cell surface MGI:3695635; PMID:17097837
GO:0055037 recycling endosome MGI:3695780; PMID:16905747
GO:0055037 recycling endosome MGI:3695780; PMID:16905747
PR:P49282-2 mSLC11A2/iso:1
natural resistance-associated macrophage protein 2 isoform IRE (mouse)
"A natural resistance-associated macrophage protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]		 acts_upstream_of_or_withinGO:0006824 cobalt ion transport MGI:3603092; PMID:16142913
GO:0006826 iron ion transport MGI:3603092; PMID:16142913
GO:0033212 iron import into cell MGI:3037617; PMID:15024413
enablesGO:0005381 iron ion transmembrane transporter activity MGI:3603092; PMID:16142913
GO:0015087 cobalt ion transmembrane transporter activity MGI:3603092; PMID:16142913
GO:0015093 ferrous iron transmembrane transporter activity MGI:3037617; PMID:15024413
located_inGO:0005769 early endosome MGI:2667558; PMID:12724326
GO:0005886 plasma membrane MGI:2667558; PMID:12724326
GO:0005903 brush border MGI:3619154; PMID:11090085
GO:0005903 brush border MGI:3619154; PMID:11090085
GO:0012505 endomembrane system MGI:2667558; PMID:12724326