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Protein Ontology report - interleukin-1 receptor-associated kinase 1 isoform 1 (human)
PR:P51617-1 -
http://purl.obolibrary.org/obo/PR_P51617-1
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:P51617-1
PRO name
interleukin-1 receptor-associated kinase 1 isoform 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hIRAK1/iso:1
Other
:
EXACT:
interleukin-1 receptor-associated kinase 1 isoform a (human)
Definition
"An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
PRO Category
organism-sequence
Parent
PR:000021973
PR:P51617
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
0
Organism-Sequence
1
Modification
0
Organism-Modification
4
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P51617-1
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-sequence
PR:P51617-1
interleukin-1 receptor-associated kinase 1 isoform 1 (human), hIRAK1/iso:1
Yes
organism-modification
PR:000027492
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human), hIRAK1/iso:1/Phos:3
Yes
organism-modification
PR:000027493
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human), hIRAK1/iso:1/Phos:4
Yes
organism-modification
PR:000027494
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human), hIRAK1/iso:1/Phos:1
Yes
Yes
organism-modification
PR:000061935
interleukin-1 receptor-associated kinase 1 isoform 1 phosphoserine and phosphothreonine form (human), hIRAK1/iso:1/pSerThr+
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hIRAK1/iso:1
forms found in complexes
hIRAK1/iso:1
Component
Complexes
PR:000027494
hIRAK1/iso:1/Phos:1
PR:000027495
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000027492
hIRAK1/iso:1/Phos:3
UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047 | pp-IRAK1 (human)
acts_upstream_of_or_within
GO:0070498
interleukin-1-mediated signaling pathway
PMID:14625308
enables
GO:0004674
protein serine/threonine kinase activity
PMID:14625308
PR:000027493
hIRAK1/iso:1/Phos:4
UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046 | hp-IRAK1 (human)
acts_upstream_of_or_within
GO:0070498
interleukin-1-mediated signaling pathway
PMID:14625308
enables
GO:0004674
protein serine/threonine kinase activity
PMID:14625308
NOT
GO:0005515
protein binding
with
PR:Q99836
hMYD88
PMID:14625308
NOT
GO:0005515
protein binding
PMID:14625308
PR:000027494
hIRAK1/iso:1/Phos:1
UniProtKB:P51617-1, Thr-209, MOD:00047
enables
GO:0005515
protein binding
with
PR:Q9NWZ3
hIRAK4
PMID:11960013
GO:0016301
kinase activity
PMID:11960013
PR:P51617-1
hIRAK1/iso:1
interleukin-1 receptor-associated kinase 1 isoform a (human)
acts_upstream_of_or_within
GO:0070498
interleukin-1-mediated signaling pathway
PMID:14625308
enables
GO:0005515
protein binding
with
PR:Q99836
hMYD88
PMID:14625308
GO:0005515
protein binding
with
PR:Q9Y4K3
E3 ubiquitin-protein ligase TRAF6 (human)
PMID:14625308