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Documentation
Protein Ontology report - pituitary homeobox 2 (mouse)
PR:P97474 -
http://purl.obolibrary.org/obo/PR_P97474
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:P97474
PRO name
pituitary homeobox 2 (mouse)
Synonyms
PRO-Short-label
:
EXACT:
mPITX2
Gene-based
:
RELATED:
Arp1 | Brx1 | Otlx2 | Pitx2 | Ptx2 | Rgs
Other
:
EXACT:
ALL1-responsive protein ARP1 (mouse) | BRX1 homeoprotein (mouse) | homeobox protein PITX2 (mouse) | orthodenticle-like homeobox 2 (mouse) | paired-like homeodomain transcription factor 2 (mouse) | paired-like homeodomain transcription factor Munc 30 (mouse) | solurshin (mouse)
Definition
"A pituitary homeobox 2 that is encoded in the genome of mouse." [
OMA:P97474
, PRO:DNx]
PRO Category
organism-gene
Parent
PR:000000117
PR:000029032
Gene Template
MGI:109340
Pitx2 (mouse)
Taxon
NCBITaxon:10090
Mus musculus
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
6
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P97474
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:P97474
pituitary homeobox 2 (mouse), mPITX2
organism-sequence
PR:000036295
pituitary homeobox 2 isoform 4 (mouse), mPITX2/iso:4
organism-sequence
PR:P97474-1
pituitary homeobox 2 isoform Ptx2B (mouse), mPITX2/iso:Ptx2B
Yes
organism-sequence
PR:P97474-2
pituitary homeobox 2 isoform Ptx2C (mouse), mPITX2/iso:Ptx2C
Yes
organism-sequence
PR:P97474-3
pituitary homeobox 2 isoform Ptx2A (mouse), mPITX2/iso:Ptx2A
Yes
organism-sequence
PR:P97474-4
pituitary homeobox 2 isoform Ptx2Calpha (mouse), mPITX2/iso:Ptx2Calpha
organism-sequence
PR:P97474-5
pituitary homeobox 2 isoform Ptx2Cbeta (mouse), mPITX2/iso:Ptx2Cbeta
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:P97474-1
mPITX2/iso:Ptx2B
pituitary homeobox 2 isoform ARP1B (mouse) | pituitary homeobox 2 isoform BRX1B (mouse)
acts_upstream_of_or_within
GO:0007368
determination of left/right symmetry
PMID:12397115
GO:0016055
Wnt signaling pathway
PMID:12464179
located_in
GO:0005667
transcription factor complex
PMID:12464179
;
PMID:15385555
PR:P97474-2
mPITX2/iso:Ptx2C
pituitary homeobox 2 isoform ARP1C (mouse) | pituitary homeobox 2 isoform BRX1A (mouse)
acts_upstream_of_or_within
GO:0007179
transforming growth factor beta receptor signaling pathway
PMID:10585561
GO:0007368
determination of left/right symmetry
PMID:9708732
GO:0007520
myoblast fusion
MGI:3686567
;
PMID:16958127
GO:0009887
animal organ morphogenesis
PMID:10585561
GO:2000288
positive regulation of myoblast proliferation
MGI:3686567
;
PMID:16958127
PR:P97474-3
mPITX2/iso:Ptx2A
pituitary homeobox 2 isoform ARP1A (mouse)
acts_upstream_of_or_within
GO:0007266
Rho protein signal transduction
PMID:11854422
NOT
GO:0007368
determination of left/right symmetry
PMID:10585561
GO:0030036
actin cytoskeleton organization
PMID:11854422
GO:0043388
positive regulation of DNA binding
MGI:3796777
;
PMID:18458156
enables
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
MGI:3796777
;
PMID:18458156
GO:0003677
DNA binding
MGI:3796777
;
PMID:18458156
GO:0003712
transcription coregulator activity
MGI:3796777
;
PMID:18458156
GO:0005515
protein binding
MGI:3796777
;
PMID:18458156
GO:0008134
transcription factor binding
PMID:15385555
located_in
GO:0005634
nucleus
PMID:11854422
GO:0005634
nucleus
PMID:11854422
