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Protein Ontology report - vascular endothelial growth factor A, long form (mouse)
PR:Q00731 - http://purl.obolibrary.org/obo/PR_Q00731
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q00731   
  PRO namevascular endothelial growth factor A, long form (mouse) 
  Synonyms
PRO-Short-label: EXACT:mVEGFA
Gene-based: RELATED:Vegf | Vegfa
Other: EXACT:L-VEGF (mouse) | vascular permeability factor (mouse) | VPF (mouse)
  Definition"A vascular endothelial growth factor A, long form that is encoded in the genome of mouse." [OMA:Q00731, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000017284 vascular endothelial growth factor A, long form
PR:000029032 Mus musculus protein
  Gene TemplateMGI:103178 Vegfa (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 7                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q00731
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q00731 vascular endothelial growth factor A, long form (mouse), mVEGFA

organism-sequence


PR:Q00731-1 vascular endothelial growth factor A, long form isoform 1 (mouse), mVEGFA/iso:1

organism-sequence


PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse), mVEGFA/iso:2
Yes
organism-sequence


PR:Q00731-3 vascular endothelial growth factor A, long form isoform 3 (mouse), mVEGFA/iso:3
Yes
organism-sequence


PR:Q00731-4 vascular endothelial growth factor A, long form isoform 4 (mouse), mVEGFA/iso:4
Yes
organism-sequence


PR:Q00731-5 vascular endothelial growth factor A, long form isoform mVEGF-5 (mouse), mVEGFA/iso:mVEGF-5

organism-sequence


PR:Q00731-6 vascular endothelial growth factor A, long form isoform 6 (mouse), mVEGFA/iso:6

organism-sequence


PR:Q00731-7 vascular endothelial growth factor A, long form isoform mL-VEGF-2 (mouse), mVEGFA/iso:mL-VEGF-2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q00731-2 mVEGFA/iso:2
VEGF-1 (mouse) | VEGF164 (mouse)
"A vascular endothelial growth factor A, long form isoform 2 that is encoded in the genome of mouse." [PMID:8614412, PRO:KRC]		 acts_upstream_of_or_withinGO:0001525 angiogenesis MGI:3758404; PMID:17626017
GO:0001569 branching involved in blood vessel morphogenesis MGI:3710026; PMID:17428830
GO:0001938 positive regulation of endothelial cell proliferation MGI:74931; PMID:1592003
GO:0002053 positive regulation of mesenchymal cell proliferation MGI:3613102; PMID:16375885
GO:0030324 lung development MGI:3613102; PMID:16375885
GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI:74931; PMID:1592003
GO:0048754 branching morphogenesis of an epithelial tube MGI:3613102; PMID:16375885
GO:0060426 lung vasculature development MGI:1927039; PMID:11066091
enablesGO:0005102 signaling receptor binding MGI:3758404; PMID:17626017
GO:0005515 protein binding MGI:1860784; PMID:10705382
GO:0008201 heparin binding MGI:77585; PMID:8614412
GO:0008201 heparin binding MGI:77585; PMID:8614412
GO:0043183 vascular endothelial growth factor receptor 1 binding MGI:3758404; PMID:17626017
GO:0043184 vascular endothelial growth factor receptor 2 binding MGI:1860784; PMID:10705382
GO:0043184 vascular endothelial growth factor receptor 2 binding MGI:1860784; PMID:10705382
GO:0050840 extracellular matrix binding MGI:3758404; PMID:17626017
located_inGO:0005576 extracellular region MGI:77585; PMID:8614412
PR:Q00731-3 mVEGFA/iso:3
VEGF-2 (mouse) | VEGF120 (mouse)
"A vascular endothelial growth factor A, long form isoform 3 that is encoded in the genome of mouse." [PMID:8614412, PRO:KRC]		 acts_upstream_of_or_withinGO:0001525 angiogenesis MGI:3758404; PMID:17626017
GO:0001938 positive regulation of endothelial cell proliferation MGI:74931; PMID:1592003
GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI:74931; PMID:1592003
located_inGO:0005576 extracellular region MGI:77585; PMID:8614412
GO:0005615 extracellular space MGI:74931; PMID:1592003
PR:Q00731-4 mVEGFA/iso:4
VEGF-4 (mouse) | VEGF115 (mouse)
"A vascular endothelial growth factor A, long form (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00731-4." [PMID:9446618, PRO:KRC]		 acts_upstream_of_or_withinGO:0001938 positive regulation of endothelial cell proliferation MGI:1195544; PMID:9446618
enablesGO:0008083 growth factor activity MGI:1195544; PMID:9446618
located_inGO:0005576 extracellular region MGI:1195544; PMID:9446618