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Protein Ontology report - activin receptor type-1 (human)
PR:Q04771 - http://purl.obolibrary.org/obo/PR_Q04771
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q04771   
  PRO nameactivin receptor type-1 (human) 
  Synonyms
PRO-Short-label: EXACT:hACVR1
Gene-based: RELATED:ACVR1 | ACVRLK2
Other: EXACT:activin receptor type I (human) | activin receptor-like kinase 2 (human) | ACTR-I (human) | ALK-2 (human) | serine/threonine-protein kinase receptor R1 (human) | SKR1 (human)
  Definition"An activin receptor type-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q04771
  CommentRequested by=PubChem. 
  PRO Categoryorganism-gene 
  ParentPR:000000067
PR:000029067
  Gene TemplateHGNC:171 ACVR1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q04771
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q04771 activin receptor type-1 (human), hACVR1


organism-sequence



PR:000000200 activin receptor type-1 sequence variant R206H (human), hACVR1/var:R206H

Yes

organism-sequence



PR:Q04771-1 activin receptor type-1 isoform 1 (human), hACVR1/iso:1


organism-modification



PR:000036435 activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human), hACVR1/iso:1/SigPep-/Phos:1

Yes

organism-modification



PR:000068633 activin receptor type-1 cysteinylated 1 (human), hACVR1/Cyst:1


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000200
hACVR1/var:R206H
UniProtKB:Q04771, Arg-206, CHEBI:29979 | activin receptor type-1 sequence variant 1 (human)
associated_with_disease_progressionDO:13374 fibrodysplasia ossificans progressiva PMID:8397373
located_inGO:0005886 plasma membrane PMID:8397373
PR:000036435
hACVR1/iso:1/SigPep-/Phos:1
acts_upstream_of_or_withinGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PMID:8242742; PMID:8389764
enablesGO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8389764
GO:0048185 activin binding PMID:8242742
located_inGO:0005886 plasma membrane PMID:8242742; PMID:8397373
GO:0048179 activin receptor complex PMID:8242742