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Protein Ontology report - potassium voltage-gated channel subfamily H member 2 (human)
PR:Q12809 - http://purl.obolibrary.org/obo/PR_Q12809
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q12809   
  PRO namepotassium voltage-gated channel subfamily H member 2 (human) 
  Synonyms
PRO-Short-label: EXACT:hKCNH2
Gene-based: RELATED:ERG | ERG1 | HERG | KCNH2
Other: EXACT:Eag homolog (human) | Eag-related protein 1 (human) | ERG-1 (human) | ether-a-go-go-related gene potassium channel 1 (human) | ether-a-go-go-related protein 1 (human) | H-ERG | hERG-1 | hERG1 | voltage-gated potassium channel subunit Kv11.1 (human)
  Definition"A voltage-gated potassium channel KCNH2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q12809
  PRO Categoryorganism-gene 
  ParentPR:000000791
PR:000029067
  Gene TemplateHGNC:6251 KCNH2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q12809
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q12809 potassium voltage-gated channel subfamily H member 2 (human), hKCNH2

Yes

organism-sequence



PR:Q12809-1 potassium voltage-gated channel subfamily H member 2 isoform A (human), hKCNH2/iso:A

Yes

organism-modification



PR:000036581 voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 (human), hKCNH2/iso:A/NGlyco:1

Yes

organism-modification



PR:000036583 voltage-gated potassium channel KCNH2 isoform A phosphorylated 1 (human), hKCNH2/iso:A/Phos:1

Yes

organism-modification



PR:000045392 voltage-gated potassium channel KCNH2 isoform A unglycosylated 1 (human), hKCNH2/iso:A/UnGlyco:1

Yes

organism-modification



PR:000045393 voltage-gated potassium channel KCNH2 isoform A unphosphorylated form (human), hKCNH2/iso:A/PhosRes-

Yes

organism-sequence



PR:Q12809-2 potassium voltage-gated channel subfamily H member 2 isoform B (human), hKCNH2/iso:B

Yes

organism-sequence



PR:Q12809-4 potassium voltage-gated channel subfamily H member 2 isoform h4 (human), hKCNH2/iso:h4


organism-sequence



PR:Q12809-5 potassium voltage-gated channel subfamily H member 2 isoform A-USO (human), hKCNH2/iso:A-USO

Yes

organism-sequence



PR:Q12809-6 potassium voltage-gated channel subfamily H member 2 isoform B-USO (human), hKCNH2/iso:B-USO


organism-sequence



PR:Q12809-7 potassium voltage-gated channel subfamily H member 2 isoform h3.1 (human), hKCNH2/iso:h3.1


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036581
hKCNH2/iso:A/NGlyco:1
UniProtKB:Q12809-1, Asn-598, MOD:00160 | hKCNH2/iso:1/Glyco:1 | voltage-gated potassium channel KCNH2 isoform 1 glycosylated 1 (human)
located_inGO:0008076 voltage-gated potassium channel complex PMID:12063277
GO:0009986 cell surface PMID:12063277
PR:000036583
hKCNH2/iso:A/Phos:1
hKCNH2/iso:1/Phos:1 | voltage-gated potassium channel KCNH2 isoform 1 phosphorylated 1 (human)
enablesdecreased GO:0005251 delayed rectifier potassium channel activity relative to PR:000002666 KCNH2/iso:1/UnMod PMID:10837251
located_inGO:0008076 voltage-gated potassium channel complex PMID:10837251
PR:000045392
hKCNH2/iso:A/UnGlyco:1
UniProtKB:Q12809-1, Asn-598, PR:000026291
located_inGO:0009986 cell surface PMID:12063277
PR:000045393
hKCNH2/iso:A/PhosRes-
enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:10837251; PMID:9351446
PR:Q12809
hKCNH2
ERG | ERG1 | HERG | KCNH2 | Eag homolog (human) | Eag-related protein 1 (human) | ERG-1 (human) | ether-a-go-go-related gene potassium channel 1 (human) | ether-a-go-go-related protein 1 (human) | H-ERG | hERG-1 | hERG1 | voltage-gated potassium channel subunit Kv11.1 (human)
acts_upstream_of_or_withinGO:0006936 muscle contraction PMID:7736582
GO:0008016 regulation of heart contraction PMID:7736582
PR:Q12809-1
hKCNH2/iso:A
enablesGO:0030552 cAMP binding PMID:10837251
PR:Q12809-2
hKCNH2/iso:B
enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:9351446
PR:Q12809-5
hKCNH2/iso:A-USO
enablesaltered|contributes_to GO:0005251 delayed rectifier potassium channel activity relative to PR:000002666 KCNH2/iso:1/UnMod PMID:9765245
located_inGO:0008076 voltage-gated potassium channel complex PMID:9765245