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Documentation
Protein Ontology report - cochlin (mouse)
PR:Q62507 -
http://purl.obolibrary.org/obo/PR_Q62507
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:Q62507
PRO name
cochlin (mouse)
Synonyms
PRO-Short-label
:
EXACT:
mCOCH
Gene-based
:
RELATED:
Coch
Other
:
EXACT:
COCH-5B2 (mouse)
Definition
"A cochlin that is encoded in the genome of mouse." [
OMA:Q62507
, PRO:DNx]
PRO Category
organism-gene
Parent
PR:000005683
cochlin
PR:000029032
Mus musculus protein
Gene Template
MGI:1278313
Coch (mouse)
Taxon
NCBITaxon:10090
Mus musculus
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
0
Modification
0
Organism-Modification
6
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:Q62507
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:Q62507
cochlin (mouse), mCOCH
union
PR:000037266
cochlin N-terminal fragment (mouse), mCOCH/Nter
Yes
organism-modification
PR:000037261
cochlin p8 (mouse), mCOCH/Clv:p8
organism-modification
PR:000037262
cochlin p18 (mouse), mCOCH/Clv:p18
organism-modification
PR:000037260
cochlin, signal peptide removed form (mouse), mCOCH/SigPep-
Yes
organism-modification
PR:000037261
cochlin p8 (mouse), mCOCH/Clv:p8
Yes
organism-modification
PR:000037263
cochlin p40 (mouse), mCOCH/Clv:p40
Yes
organism-modification
PR:000037264
cochlin, signal peptide removed glycosylated form (mouse), mCOCH/SigPep-/GlycoRes+
organism-modification
PR:000037262
cochlin p18 (mouse), mCOCH/Clv:p18
Yes
organism-modification
PR:000037265
cochlin precursor (mouse), mCOCH/precursor
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000037260
mCOCH/SigPep-
UniProtKB:Q62507, 27-552
"A cochlin (mouse) that the signal peptide has been removed. UniProtKB:Q62507, 27-552." [PMID:23684986, PRO:KRC]
located_in
GO:0031012
extracellular matrix
MGI:5525040
;
PMID:23684986
PR:000037261
mCOCH/Clv:p8
UniProtKB:Q62507, 26-134 | N-terminal fragment (mouse)
"A cochlin, signal peptide removed form (mouse) that results from cleavage downstream of the LCCL domain (Pfam:PF03815) by aggrecanases proteolytic activity. This form results from the deglycosylation of the N-terminal fragment p18. UniProtKB:Q62507, 26-134." [PMID:23684986, PRO:KRC]
located_in
GO:0005576
extracellular region
MGI:5525040
;
PMID:23684986
PR:000037262
mCOCH/Clv:p18
UniProtKB:Q62507, 26-134, MOD:00693 | N-terminal fragment glycosylated (mouse)
"A cochlin, signal peptide removed form (mouse) that results from cleavage downstream of the LCCL domain (Pfam:PF03815), and includes at least one glycosylated residue. UniProtKB:Q62507, 26-134, MOD:00693." [PMID:23684986, PRO:KRC]
located_in
GO:0005576
extracellular region
MGI:5525040
;
PMID:23684986
PR:000037263
mCOCH/Clv:p40
UniProtKB:Q62507, 135-552 | cochlin C-terminal fragment (mouse)
"A cochlin, signal peptide removed form (mouse) that results from further cleavage of the LCCL domain (Pfam:PF03815) after aggrecanases proteolytic activity. UniProtKB:Q62507, 135-552." [PMID:23684986, PRO:KRC]
located_in
GO:0031012
extracellular matrix
MGI:5525040
;
PMID:23684986
PR:000037266
mCOCH/Nter
"A cochlin (mouse) that consists of the region upstream of LCCL domain (Pfam:PF03815) without the signal peptide. The fragment may or may not be glycosylated." [PMID:23684986, PRO:KRC]
acts_upstream_of_or_within
GO:0042742
defense response to bacterium
MGI:5525040
;
PMID:23684986
GO:0045089
positive regulation of innate immune response
MGI:5525040
;
PMID:23684986
