PRO Term |
GO Annotation |
Evidence |
PR:000036558 mSMAD3/iso:1/Phos:1 UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046 "A smad3 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046." [PMID:10823886, PMID:12943993, PMID:15282343, PMID:15464984, PMID:9702197, PRO:CNA] |
enables | GO:0003690 double-stranded DNA binding |
PMID:15282343 |
GO:0003700 DNA-binding transcription factor activity |
PMID:10823886; PMID:12943993 |
GO:0008134 transcription factor binding |
PMID:15464984; PMID:9702197 |
located_in | GO:0005634 nucleus |
PMID:12943993; PMID:15282343 |
GO:0005667 transcription factor complex |
PMID:9702197 |
PR:000036560 mSMAD3/iso:1/Phos:2 UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047|Ser-213, MOD:00046 "A smad3 isoform 1 phosphorylated 2 in mouse. UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047|Ser-213, MOD:00046." [PMID:15241418, PRO:CNA, PRO:DAN] |
enables | decreased GO:0003700 DNA-binding transcription factor activity relative to PR:000036558 mSMAD3/iso:1/Phos:1 |
PMID:15241418 |
PR:000036561 mSMAD3/iso:1/Phos:3 UniProtKB:Q8BUN5-1, Thr-179, MOD:00047|Ser-204/Ser-208/Ser-213, MOD:00046 "A smad3 isoform 1 phosphorylated 3 in mouse. UniProtKB:Q8BUN5-1, Thr-179, MOD:00047|Ser-204/Ser-208/Ser-213, MOD:00046." [PMID:10197981, PRO:CNA, PRO:DAN] |
enables | NOT GO:0003713 transcription coactivator activity |
PMID:10197981 |
located_in | GO:0005737 cytoplasm |
PMID:10197981 |
PR:Q8BUN5-1 mSMAD3/iso:1
"A smad3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA] |
acts_upstream_of_or_within | GO:0007179 transforming growth factor beta receptor signaling pathway |
PMID:12543979 |
enables | GO:0005515 protein binding with PR:000036434 mTGFBR1/iso:1/SigPep-/Phos:1 |
PMID:12154125 |
GO:0005515 protein binding with PR:A2A8R0 mZFYVE9/iso:1 |
PMID:12154125 |