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Protein Ontology report - sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (mouse)
PR:Q8R2F2 -
http://purl.obolibrary.org/obo/PR_Q8R2F2
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:Q8R2F2
PRO name
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (mouse)
Synonyms
PRO-Short-label
:
EXACT:
mDEGS2
Gene-based
:
RELATED:
Degs2
Other
:
EXACT:
degenerative spermatocyte homolog 2 (mouse) | sphingolipid 4-desaturase (mouse) | sphingolipid C4-monooxygenase (mouse)
Definition
"A sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 that is encoded in the genome of mouse." [
OMA:Q8R2F2
, PRO:DNx]
PRO Category
organism-gene
Parent
PR:000006414
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2
PR:000029032
Mus musculus protein
Gene Template
MGI:1917309
Degs2 (mouse)
Taxon
NCBITaxon:10090
Mus musculus
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
2
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:Q8R2F2
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:Q8R2F2
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (mouse), mDEGS2
Yes
organism-sequence
PR:Q8R2F2-1
sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse), mDEGS2/iso:1
Yes
organism-sequence
PR:Q8R2F2-2
sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 2 (mouse), mDEGS2/iso:2
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:Q8R2F2
mDEGS2
Degs2 | degenerative spermatocyte homolog 2 (mouse) | sphingolipid 4-desaturase (mouse) | sphingolipid C4-monooxygenase (mouse)
"A sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 that is encoded in the genome of mouse." [OMA:Q8R2F2, PRO:DNx]
acts_upstream_of_or_within
GO:0006667
sphinganine metabolic process
PMID:11937514
GO:0030148
sphingolipid biosynthetic process
PMID:11937514
enables
GO:0042284
sphingolipid delta-4 desaturase activity
PMID:11937514
PR:Q8R2F2-1
mDEGS2/iso:1
"A sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
acts_upstream_of_or_within
GO:0006667
sphinganine metabolic process
MGI:3694278
;
PMID:16571104
GO:0046513
ceramide biosynthetic process
MGI:3694278
;
PMID:16571104
enables
GO:0000170
sphingosine hydroxylase activity
MGI:3056825
;
PMID:15474011
GO:0000170
sphingosine hydroxylase activity
MGI:3056825
;
PMID:15474011