PRO Term |
GO Annotation |
Evidence |
PR:Q9HCE7 hSMURF1 KIAA1625 | SMURF1 | HECT-type E3 ubiquitin transferase SMURF1 (human) | SMAD ubiquitination regulatory factor 1 (human) | SMAD-specific E3 ubiquitin-protein ligase 1 (human) "An E3 ubiquitin-protein ligase SMURF1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9HCE7] |
acts_upstream_of_or_within | GO:0030514 negative regulation of BMP signaling pathway |
PMID:10458166 |
PR:Q9HCE7-2 hSMURF1/iso:Short
"An E3 ubiquitin-protein ligase SMURF1 isoform Short that is encoded in the genome of human." [PRO:CNA] |
acts_upstream_of_or_within | GO:0006511 ubiquitin-dependent protein catabolic process |
PMID:12857866 |
GO:0006511 ubiquitin-dependent protein catabolic process |
PMID:12857866 |
GO:0036211 protein modification process |
PMID:10458166 |
enables | GO:0004842 ubiquitin-protein transferase activity |
PMID:10458166 |
GO:0005515 protein binding |
PMID:11278251; PMID:16299379 |
located_in | GO:0005622 intracellular anatomical structure |
PMID:10458166 |