cytokine and chemokine mediated signaling pathway
signaling pathway pertinent to immunity
chemokine mediated signaling pathway
2010-11-03T04:27:00Z
Chemokine receptors bind chemokines
Chemokine-initiated pathways play important roles in innate and adaptive immunity. They are also involved in development and tissue maintenance. The presence and localization of four cysteines is important for structural folding and is also the basis for chemokine classification. The spacing between the first two cysteine residues divides the family members into four groups. Most mammalian chemokines belong to the CC and CXC families. Chemokines signal via G-protein-coupled receptors to engage distinct G-protein signaling and downstream cascades.
PW:0000829
VPetri
chemokine-mediated signaling pathway
pathway