Alzheimer's Disease Ontology (ADO) 2.0.1 Astghik Sargsyan Bide Zhang Philipp Wegner Stephan Gebel https://creativecommons.org/licenses/by/4.0/ Vanessa Lage-Rupprecht Alpha Tom Kodamullil Alzheimer's Disease Ontology is a knowledge-based ontology that encompasses varieties of concepts related to Alzheimer'S Disease, foundamentally structured by upper level Basic Formal Ontology(BFO). This Ontology is enriched by the interrelational entities that demonstrate the nextwork of the understanding on Alzheimer's disease and can be readily applied for text mining. Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification. Really of interest to developers only BFO OWL specification label Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2 Person:Alan Ruttenberg Really of interest to developers only BFO CLIF specification label An annotation property that represents an ID used in the NIH LINCS project. An annotation property that represents an LINCS ID of a cell line. 表示细胞系的LINCS ID的注释属性。 Oliver He, Jiangan Xie Oliver He, Jiangan Xie Oliver He, Jiangan Xie, Jie Zheng Cell line LINCS ID LINCS ID 细胞系LINCS ID 细胞系LINCS ID has_RxCUI IHCC category IHCC browser label editor preferred label editor preferred label editor preferred term editor preferred term editor preferred term~editor preferred label 编辑首选术语 编辑首选标签 The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English) 对于一类或属性的简洁的、有意义的、与人类友好的名称由本体开发商首选。 （美国英语） PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> editor preferred label editor preferred label editor preferred term editor preferred term editor preferred term~editor preferred label editor preferred term~editor preferred label 编辑首选术语 编辑首选术语 编辑首选术语~编辑首选标签 编辑首选标签 编辑首选标签 example example of usage A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold. PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> IAO:0000112 uberon example_of_usage true example_of_usage example of usage example of usage has curation status 有管理状态 PERSON:Alan Ruttenberg PERSON:Bill Bug PERSON:Melanie Courtot OBI_0000281 has curation status has curation status 有管理状态 有管理状态 definition definition textual definition textual definition 定义 A property representing the English language definitions of what NCI means by the concept. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software. English language definitions of what NCI means by the concept. These are limited to 1024 characters. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software. OBI的官方定义，解释类或属性的含义。应该是亚里士多德式的，形式化和规范化的。 可以通过口语定义进行扩充。 The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. 官方的定义，解释类或属性的含义。应该是亚里士多德式的，形式化和规范化的。 可以通过口语定义进行扩充。 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. 2012-04-05: Barry Smith OBI的官方定义解释了一个类或属性的含义：'应该是亚里士多德式的，形式化和规范化的。可以用口语定义'是糟糕的。 您能解决这样的问题吗？ 解释关于类或属性的表达含义的必要和充分条件的陈述。 Alan Ruttenberg 您提出的定义是一个合理的备选，除非它很常见，没有给出必要和充分的条件。大多数情况下它们是必要的，偶尔是必要的，充分的或者仅仅仅充分的。它们通常使用不是自己定义的术语，因此它们实际上不能通过这些标准进行评估。 关于拟议定义的具体内容： 我们没有“含义”，或“表达”或“属性”的定义。对于在预期意义上的“参考”，我认为我们使用术语“指示”。对于'表达'，我认为我们和你的意思是符号，或标识符。对于“含义”，它不同于类和属性。对于类，我们希望文档能够让读者确定一个实体是否是该类的实例。对于属性，让我们的目标读者决定，给定一对潜在的关系，判断关系成立的断言正确与否。 “目标读者”部分表明我们也指定了我们期望的能够理解定义的人，并且概括了人类和计算机读者以包含文本和逻辑定义。 就我个人而言，我更愿意削弱对文档的定义，并指出什么是可取的。 我们还有一个悬而未决的问题，就是如何针对不同的受众定位不同的定义。临床读者阅读chebi需要来自受过化学训练的受众的不同类型的定义文档/定义，同样需要一个适合本体工作者的定义。 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. PERSON:Daniel Schober DEFINITION GROUP:OBI:<http://purl.obolibrary.org/obo/obi> no DEFINITION definition definition textual definition textual definition 定义 定义 文本定义 文本定义 editor note 编者注 An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology. 管理者注释用于其编辑器。它可能不包含在本体的出版版本中，所以它应该不包含最终用户了解本体所需的信息。 PERSON:Daniel Schober GROUP:OBI:<http://purl.obfoundry.org/obo/obi> GROUP:OBI:<http://purl.obofoundry.org/obo/obi> IAO:0000116 IAO:0000116 uberon uberon editor_note editor_note 编辑_注释 true editor_note editor_note 编辑_注释 IAO:0000116 IAO:0000116 uberon uberon editor_note editor_note 1 true editor_note editor_note editor note editor note 编者注 编者注 IAO:0000116 definition editor term editor 术语编辑者 Name of editor entering the definition in the file. The definition editor is a point of contact for information regarding the term. The definition editor may be, but is not always, the author of the definition, which may have been worked upon by several people Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people 输入文件中术语编辑者的名称。术语编辑者是有关术语的信息交汇点。术语编辑者可以是，但并不总是，定义的作者，这可能是由几个人完成 20110707, MC: label update to term editor and definition modified accordingly. See http://code.google.com/p/information-artifact-ontology/issues/detail?id=115. 20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115. 20110707，MC：术语编辑和定义进行相应的修改。见http://code.google.com/p/information-artifact-ontology/issues/detail?id=115。 PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> definition editor definition editor definition_editor term editor term editor 术语编辑者 术语编辑者 alternative term 替代术语 An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent) 一类或属性的替代名称，这意味着与所述首选名称同样的事物（语义上等价） PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> alternative term alternative term 替代术语 替代术语 definition source 定义来源 Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007 formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007 正式引用，例如在外部数据库中的标识符，用于表示/定义的属性源（S）。自由文本表示/为定义属性源（S）。实例：在2007年1月31日的作者姓名，URI，MeSH术语C04，PUBMEDID，维基uri PERSON:Daniel Schober Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w GROUP:OBI:<http://purl.obolibrary.org/obo/obi> 论OBO-讨论邮件-列表，请参阅http://bit.ly/hgm99w definition source definition source definition_source 定义来源 定义来源 curator note An administrative note of use for a curator but of no use for a user PERSON:Alan Ruttenberg IAO:0000232 uberon curator_notes 1 true curator_notes curator note curator note curator notes IAO:0000233 external term_tracker_item true true term_tracker_item term tracker item imported from 引自 For external terms/classes, the ontology from which the term was imported 外部术语/类，术语引入的本体 PERSON:Alan Ruttenberg PERSON:Melanie Courtot GROUP:OBI:<http://purl.obolibrary.org/obo/obi> imported from imported from 引自 引自 expand assertion to OBO foundry unique label An alternative name for a class or property which is unique across the OBO Foundry. The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = 'sequence ' + [label], etc. , MA could specify 'mouse + [label]' etc. Upon importing terms, ontology developers can choose to use the 'OBO foundry unique label' for an imported term or not. The same applies to tools . The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = 'sequence ' + [label], etc. , MA could specify 'mouse + [label]' etc. Upon importing terms, ontology developers can choose to use the 'OBO foundry unique label' for an imported term or not. The same applies to tools . PERSON:Alan Ruttenberg PERSON:Bjoern Peters PERSON:Chris Mungall PERSON:Melanie Courtot GROUP:OBO Foundry <http://obofoundry.org/> OBO foundry unique label elucidation person:Alan Ruttenberg Person:Barry Smith Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms elucidation has associated axiom(nl) Person:Alan Ruttenberg Person:Alan Ruttenberg An axiom associated with a term expressed using natural language has associated axiom(nl) has associated axiom(fol) Person:Alan Ruttenberg Person:Alan Ruttenberg An axiom expressed in first order logic using CLIF syntax has associated axiom(fol) Cooper Stansbury This annotation property specifies classes that were developed as part of an alignment effort between the Common Rule Ontology and the Informed Consent Ontology in the Summer of 2018. These classes represent entities that are necessary for understanding the regularatory frameworks that influence informed consent, often at a different level of granularity than individual consent processes. These classes were created to be compatible with regulatory frameworks outside the Unitied States, hence they are general. RUBRIC an annotation property that lists keyword(s) useful for literature tagging and retrieval of sentences containing the type (or kind) of entity (e.g., interaction) as shown by the ontology term label and definition. Yongqun He has literature mining keywords an annotation property that specifies the dependency pattern of the literature keywords that match to the ontology interaction type. Arzucan Ozgur, Junguk Hur, Yongqun He has keyword dependency pattern An association created to allow the source NICHD to assign a parent to each concept with the intent of creating a hierarchy that includes only terms in which they are a contributing source. A11 Conceptual Entity Has_NICHD_Parent Has_NICHD_Parent Has_NICHD_Parent An association that indicates that a finding or lab test is related to a gene, possibly through a variant or product. A13 Conceptual Entity Related_To_Genetic_Biomarker Related_To_Genetic_Biomarker Related_To_Genetic_Biomarker An association that indicates a PCDC AML concept is a Permissible Value for a PCDC AML Variable concept. A24 Conceptual Entity Is_PCDC_AML_Permissible_Value_For_Variable Is_PCDC_AML_Permissible_Value_For_Variable Is_PCDC_AML_Permissible_Value_For_Variable An association that indicates a PCDC EWS concept is a Permissible Value for a specific PCDC EWS Variable concept. A28 Conceptual Entity Is_PCDC_EWS_Permissible_Value_For_Variable Is_PCDC_EWS_Permissible_Value_For_Variable Is_PCDC_EWS_Permissible_Value_For_Variable true A property representing a concept unique identifier within the NCI Enterprise Vocabulary Service's NCI Thesaurus. NHC0 Conceptual Entity code code code A property representing the accession number for a Protein or Gene within the OMIM database. P100 Conceptual Entity OMIM Number OMIM_Number OMIM_Number OMIM_Number A property that represents a description of the sort of thing or category to which a concept belongs in the context of the UMLS semantic network. The semantic type describes the sort of thing or category to which a concept belongs in the context of the UMLS semantic network. P106 Conceptual Entity Semantic Type Semantic_Type In general, applying semantic types aids in allowing users (or computer programs) to draw conclusions about concepts by virtue of the categories to which they have been assigned. We use a set of semantic types developed for the UMLS Metathesaurus. There are currently 134 semantic types in the UMLS. Semantic_Type Semantic_Type A property representing an alternative Preferred Name for use in some NCI systems. Provides an alternative Preferred Name for use in some NCI systems. P107 Conceptual Entity Display Name Display_Name Display Name Display_Name Display_Name A property representing the word or phrase that NCI uses by preference to refer to the concept. The word or phrase that NCI uses by preference to refer to the concept. P108 Conceptual Entity Preferred Name Preferred_Name Preferred Name Preferred Term Preferred_Name Preferred_Name A property representing the concept unique identifier (CUI) assigned by the National Library of Medicine (NLM). If a concept in any NCI-maintained knowledgebase exists in the NLM Unified Medical Language System (UMLS), NCI includes the NLM CUI among the information we provide about the concept. Concept Unique Identifiers, or CUIs, are concept numbers assigned by the National Library of Medicine (NLM). If a concept in any NCI-maintained knowledgebase exists in the NLM Unified Medical Language System (UMLS), NCI includes the NLM CUI among the information we provide about the concept. P207 Conceptual Entity UMLS CUI UMLS_CUI UMLS_CUI UMLS_CUI A property representing the concept unique identifier (CUI) for those concepts that appear in NCI Metathesaurus but not in the National Library of Medicine Unified Medical Language System (NLM UMLS). P208 Conceptual Entity NCI Metathesaurus CUI NCI_META_CUI NCI_META_CUI NCI_META_CUI A property representing the Chemical Abstracts Service number for a Chemical or Drug. P210 Conceptual Entity CAS Registry Number CAS_Registry CAS_Registry CAS_Registry A property representing the KEGG ID code for a pathway. It can be used to link a KEGG pathway reference to the primary pathway information. P215 Conceptual Entity KEGG ID KEGG_ID KEGG_ID KEGG_ID A property representing a disease or condition for which this drug is an accepted treatment. Used in the Drug, Food, Chemical or Biomedical Material branch. P302 Conceptual Entity Accepted Therapeutic Use For Accepted_Therapeutic_Use_For Accepted_Therapeutic_Use_For Accepted_Therapeutic_Use_For A property used to indicate the standing of a concept in relation to currently accepted classifications and concepts. In NCI Thesaurus concept status subtype indicates concepts with unusual and problematic characteristics that should be evaluated by people and/or programs before those concept are used. P310 Conceptual Entity Concept Status Concept_Status Concept_Status Concept_Status A property used to flag terms that are part of an FDA data standard manual, including Route of Administration, Dosage Form, Package Type and Potency. P317 Conceptual Entity FDA Table FDA_Table FDA_Table FDA_Table A property representing the FDA Unique Ingredient Identifier, a key component of the federal drug information model. P319 Conceptual Entity FDA UNII Code FDA_UNII_Code FDA_UNII_Code FDA_UNII_Code A property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake. P322 Conceptual Entity Contributing Source Contributing_Source Contributing_Source Contributing_Source A property representing the English language definition of a concept from a source other than NCI. P325 Conceptual Entity [source] Definition ALT_DEFINITION ALT_DEFINITION ALT_DEFINITION A property that is used to establish correspondence between the NCI Thesaurus concept representing a taxon (species) and the NCBI/NLM Species Taxonomy ID assigned by the NCBI to that taxon. P331 Conceptual Entity NCBI Taxon ID NCBI_Taxon_ID NCBI_Taxon_ID NCBI_Taxon_ID A property representing a concise expression about the atoms that constitute a particular chemical compound. P350 Conceptual Entity Chemical Formula Chemical_Formula CRCH Chemical Formula Chemical_Formula Chemical_Formula true A property representing a retired unique concept identifier created and stored as Concept Name by legacy EVS software. Use of these values was long discouraged, but continued as late as 2009 when creation of new values ceased and Concept Name was retired. Legacy values are intended solely to help resolve and update earlier coding. P366 Conceptual Entity Legacy Concept Name Legacy Concept Name Legacy_Concept_Name Legacy Concept Name Legacy_Concept_Name A property representing that a concept in the 'Drug, Food, Chemical or Biomedical Material' branch of the NCI thesaurus maps to a specific concept in the EBI Chemical Entities of Biological Interest (CHEBI) database. P368 Conceptual Entity CHEBI_ID CHEBI_ID CHEBI_ID A property representing that a concept in the 'Gene' branch of the NCI thesaurus maps to a HUGO Gene Nomenclature Committee (HGNC) certified gene. P369 Conceptual Entity HGNC_ID HGNC_ID HUGO_ID HGNC_ID A property representing a term chosen by NICHD to be used in the representation of the NICHD hierarchy. P371 Conceptual Entity NICHD_Hierarchy_Term NICHD NICHD_Hierarchy_Term NICHD_Hierarchy_Term A property representing that a term in another terminology has been mapped to a term in NCIt and describes the relationship between the mapped terms. P375 Conceptual Entity Maps_To Maps_To Maps_To A property representing notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept. Design notes are notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept. P98 Conceptual Entity DesignNote DesignNote DesignNote DesignNote has_MedDRA_id ISA alternative term An alternative term used by the ISA tools project (http://isa-tools.org). Requested by Alejandra Gonzalez-Beltran https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891&atid=886178 Person: Alejandra Gonzalez-Beltran Person: Philippe Rocca-Serra ISA tools project (http://isa-tools.org) ISA alternative term IEDB alternative term An alternative term used by the IEDB. PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters IEDB IEDB alternative term the symbol assigned by the nomenclature authority Oliver He, Yue Liu symbol from nomenclature authority the full name assigned by the nomenclature authority Oliver He, Yue Liu full name from nomenclature authority A GeneID in the NCBI Gene database Oliver He, Yue Liu NCBI GeneID the NCBI LocusTag name of a gene Oliver He, Yue Liu NCBI LocusTag the map location of a gene Oliver He, Yue Liu gene map location a date of content modification Oliver He, Yue Liu modification date The NCBITaxon ontology ID of an organism. Oliver He, Yue Liu organism NCBITaxon ID A chromosome ID where a gene is located. Oliver He chromosome ID of gene an annotation property that specifies the type of a gene Oliver He type of gene an annotation property that specifies a nomenclature status Oliver He nomenclature status an annotation property that shows the GO information associated with a specific gene. Yongqun He has GO association An annotation property that represents a gene's association with PubMed publication(s). Yongqun He has PubMed association An annotation property that refers to a code defined by NCIT NCIT code tooth SubClassOf 'never in taxon' value 'Aves' S never_in_taxon T iff: S SubClassOf in_taxon only not T. x never in taxon T if and only if T is a class, and x does not instantiate the class expression "in taxon some T". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL. Chris Mungall ?X DisjointWith RO_0002162 some ?Y Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: ?X and (RO_0002162 some ?Y) RO:0002161 uberon never_in_taxon true true never_in_taxon never in taxon never_in_taxon S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T. RO:0002174 uberon dubious_for_taxon true true dubious_for_taxon this relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take time to resolve. Example: metencephalon in teleost dubious_for_taxon S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S. https://orcid.org/0000-0002-6601-2165 RO:0002175 applicable for taxon uberon present_in_taxon true true present_in_taxon present in taxon present_in_taxon logical macro assertion http://purl.obolibrary.org/obo/ro/docs/shortcut-relations/ logical macro assertion on a property logical macro assertion on an object property cjm 2018-03-13T23:59:29Z is directional form of cjm 2018-03-14T00:03:16Z is positive form of An administrative note of use for a curator but of no use for a user. no organizational term IAO:0000232 editor_notes curator note A source from where the formal description was derived. This can be in the form of a link to a relevant webpage, the IRI of a term in an existing ontology, a reference to specific literature, etc. yes metadata complete - requires restrictions and relationships IAO:0000119 definition source description source An assertion of whether or not the term/class description is an adaptation of the description in the description source. Requested inclusion of this property into RO. Check details here again after inclusion. metadata complete - requires restrictions and relationships SCDO description adapted from source Description inherent in name (not provided by source) Only label adapted organizational term property has curation status An indication of whether a term/class already exists in other ontologies. Only used for term (descriptions) that were not taken directly from an existing ontology. SCDO (Jade Hotchkiss) existence in other ontologies Used to record the identifier that had been used previously but is no longer in use. SCDO (Jade Hotchkiss) previous identifier an alternative term used for STATO statistical ontology and ISA team Alejandra Gonzalez-Beltran Orlaith Burke Philippe Rocca-Serra STATO alternative term An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class. UBPROP:0000001 uberon external_definition true external_definition This annotation property may be replaced with an annotation property from an external ontology such as IAO external_definition A textual description of an axiom loss in this ontology compared to an external ontology. UBPROP:0000002 uberon axiom_lost_from_external_ontology true axiom_lost_from_external_ontology This annotation property may be replaced with an annotation property from an external ontology such as IAO axiom_lost_from_external_ontology Notes on the homology status of this class. UBPROP:0000003 uberon homology_notes true homology_notes This annotation property may be replaced with an annotation property from an external ontology such as IAO homology_notes UBPROP:0000004 uberon provenance_notes true provenance_notes provenance_notes Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. UBPROP:0000007 uberon has_relational_adjective true has_relational_adjective has_relational_adjective Notes on the how instances of this class vary across species. UBPROP:0000008 uberon taxon_notes true taxon_notes taxon_notes Notes on the structure, composition or histology of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000010 uberon structure_notes true structure_notes structure_notes Notes on the ontogenic development of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000011 uberon development_notes true development_notes development_notes Notes on how similar or equivalent classes are represented in other ontologies. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000012 uberon external_ontology_notes true external_ontology_notes external_ontology_notes FMA has terms like 'set of X'. In general we do not include set-of terms in uberon, but provide a mapping between the singular form and the FMA set term UBPROP:0000202 uberon fma_set_term true fma_set_term fma_set_term Super-property collecting all annotation properties assigning classes in ONS to specific subset (i.e. Metadata search). For each subset, there will be an annotation property. To assign a class to a subset, set the annotation property value to "TRUE" in subset of ONS Annotation properties assigning a class to the ONS-subset of metadata search classes. Set value to "TRUE" to assign a class. in minimal requirement ONS subset this indicates that the term originates from the Alzheimer Ontology by Fraunhofer SCAI from Alzheimer Ontology excluded_from_qc_check true excluded from QC check excluded_subClassOf true excluded subClassOf A metadata relation between a class and its taxonomic rank (eg species, family) ncbi_taxonomy has_rank uberon dc-contributor true dc-contributor contributor An entity primarily responsible for making the resource. (This property is used in the SCDO when a term was created by the SCDO Working Group or a curator.) The SCDO uses this especially to apply to term descriptions. no ready for release Examples of a Creator include a person, an organisation, or a service. Typically, the name of a Creator should be used to indicate the entity. An entity primarily responsible for making the content of the resource. Creator dc:creator Creator Typically, Date will be associated with the creation or availability of the resource. Recommended best practice for encoding the date value is defined in a profile of ISO 8601 [W3CDTF] and follows the YYYY-MM-DD format. A date associated with an event in the life cycle of the resource. Date Date Description may include but is not limited to: an abstract, table of contents, reference to a graphical representation of content or a free-text account of the content. http://purl.org/dc/elements/1.1/description uberon dc-description true dc-description An account of the content of the resource. Description Description description identifier_dc identifier relation uberon dc-contributor true dc-contributor contributor is referenced by relation ID of merged class. has_alternative_id has broad synonym has_broad_synonym A database cross-reference. An annotation which directs one to information contained within a database. A property representing a reference to an identical or very similar object in another database. Reference database or publication source. Conceptual Entity xRef metadata complete - requires restrictions and relationships IAO:0100001 SBO:0000554 DbXref Xref database cross-reference database_cross_reference db xref hasDbXref database cross reference database cross reference database_cross_reference database_cross_reference has database cross reference xRef 数据库_交叉_引用 数据库_交叉_引用 A property representing a fully qualified synonym, contains the string, term type, source, and an optional source code if appropriate. Each subfield is deliniated to facilitate interpretation by software. An alias in which the alias exhibits true synonymy. Example: ornithine cycle is an exact synonym of urea cycle. Exact synonym. Fully qualified synonym, contains the string, term type, source, and an optional source code if appropriate. Each subfield is deliniated to facilitate interpretation by software. no pending vetting by the SCDO developers IAO:0100001 FULL_SYN Synonym with Source Data has exact synonym hasExactSynonym has_exact_synonym has narrow synonym has_narrow_synonym Name space of the ontology. IAO:0100001 disease_ontology has_obo_namespace has_obo_namespace 有_obo_命名空间 有_obo_命名空间 Has related synonym. has related synonym has_related_synonym has synonym An identifier is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity. id An association that connects the concept defining a particular terminology subset with concepts that belong to this subset. In subset. Used to associate the concept defining a particular terminology subset with concepts that belong to this subset. Concept_In_Subset in subset in_subset shorthand IAO:0100001 shorthand shorthand Comment. comment comment Is defined by. is defined by rdfs:isDefinedBy label label A human readable name for this class. A human-readable name for the class/term. yes A human-readable name for the subject. label label rdfs:label 标签 http://www.w3.org/2000/01/rdf-schema#seeAlso seeAlso uberon seeAlso true true seeAlso see_also_rdf_schema see also see also seeAlso equivalent property A skos concept mapping used to link two concepts, indicating a high degree of confidence that the concepts can be used interchangeably. has exact match A preferred label. yes pending vetting by the SCDO developers skos:prefLabel uberon depicted_by true depicted_by depicted by alternate name library_of_congress_subject_headings Library of Congress Subject Headings http://purl.org/dc/terms/LCSH https://viaf.org/viaf/174475040 library_of_congress_classification Library of Congress Classification see_also_wikidata see also icd9cm ICD-9-CM nci_thesaurus_id NCI Thesaurus ID different_from different from viaf_id VIAF ID medical_dictionary_for_regulatory_activities_id Medical Dictionary for Regulatory Activities ID mesh_descriptor_id Such as C004931 for DPPH or D008180 for systemic lupus erythematosus. MeSH Descriptor ID snomed_ct_identifier SNOMED CT Identifier The subject describes a clinically approved drug or therapy for a condition (object). isTreatmentFor The subject describes as sign/symptom or multiple signs/symptoms for the object. isSignAndSymptomFor The subject possesses characteristics leading to an increased risk in developing a certain phenotype or condition (object). The example of risk factors could be age, family history, consumption of certain products, being exposed to chemicals or radiations, having certain underlying conditions or being infected by an microorganism isRiskFactorFor The subject serves as an in vivo model for the study of a certain phenotype (object) during pre-clinical phase. isModelFor The subject is a technique carried out in a clinical assessment for evaluation of a condition (object). isDiagnosisFor An subject that is a symptom, a sign, an underlying disease, a molecular abnormality, or a clinical result/outcome characterised as the key marker for the diagnosis/onset/classification of a certain condition (object). isClinicalMarkerFor The subject describes any process that is carried out at the cellular level, but not necessarily restricted to a single cell for the object. isCellularProcessFor A relation describing an anatomical feature of the referenced object with a material entity. isAnatomicalEntityFor The subject gene has variation that can lead to an increased disease risk, but does not directly cause a disease. VariantisGeneticRiskFactorFor positively regulates (process to process) positively regulates molecularly interacts with http://purl.obolibrary.org/obo/MI_0915 Cognitive symptoms involve problems with concentration and memory and can be just as disabling as the other types of symptoms. The onset of cognitive symptoms is usually realised in the same way as negative symptoms in that they only begin to be noticeable after the dominance of psychotic episodes or positive symptoms have either been controlled with medication or diminished with age. Modified Defintion cognitive symptom https://livingwithschizophreniauk.org/cognitive-symptoms-schizophrenia/ TM_BIN_VariantisGeneticRiskFactorFor TM_BIN_isSignAndSymptomFor TM_BIN_isTreatmentFor A sign that arises in the early/preclinical stage of a disease early clue early hint early sign A disease stage at which a person may function independently. He or she may still drive, work and be a part of social activities. Despite this, the person may feel as if he or she is having memory lapses, such as forgetting familiar words or the location of everyday objects. https://www.alz.org/alzheimers-dementia/stages Early-stage Alzheimer's Disease (mild) A disease in the middle stage where the dementia symptoms are more pronounced. The person may confuse words, get frustrated or angry, and act in unexpected ways, such as refusing to bathe. Damage to nerve cells in the brain can also make it difficult for the person to express thoughts and perform routine tasks without assistance. https://www.alz.org/alzheimers-dementia/stages Middle-stage Alzheimer's Disease (moderate) A behavioral symptom of Alzheimer's disease that encompasses getting upset, worried, and angry more easily. Acting depressed or not interested in things or hiding things or believing that other people are hiding things. It also causes to imagining things that aren't there etc. https://www.nia.nih.gov/health/managing-personality-and-behavior-changes-alzheimers#:~:text=Common%20Changes%20in%20Personality%20and%20Behavior&text=Getting%20upset%2C%20worried%2C%20and%20angry,things%20that%20aren't%20there Personality and behavioral changes A disease at late stage where dementia symptoms are severe. Individuals lose the ability to respond to their environment, to carry on a conversation and, eventually, to control movement. They may still say words or phrases, but communicating pain becomes difficult. As memory and cognitive skills continue to worsen, significant personality changes may take place and individuals need extensive care. https://www.alz.org/alzheimers-dementia/stages Dementia-stage Alzheimer's Disease Late-stage Alzheimer's Disease(severe) A disease stage of Alzheimer's disease that begins long before any symptoms become apparent. The symptoms go unnoticed by the patients and people around them and this stage can last for years, possibly even decades. https://pubmed.ncbi.nlm.nih.gov/21514248/ preclinical Alzheimer preclinical stage of Alzheimer's disease A stage of Alzheimer's disease where symptoms appear such as concern regarding a change in cognition (raised either by the patient himself/herself or by an informant who knows the patient well), impairment in one or more cognitive domains, preservation of independence in functional abilities and other non-demented symptoms. https://pubmed.ncbi.nlm.nih.gov/21514249/ predementia phase of Alzheimer's disease mild cognitive impairment due to Alzheimer's disease A disease of which the patient at this stage suffer from memory loss, impaired ability to think, or making decisions that interferes with doing everyday activities. https://pubmed.ncbi.nlm.nih.gov/27307128/ dementia due to Alzheimer's disease An emotion milder than worry raised by either the patient, or the informant who knows the patient well, or from a skilled clinician observing, about cognitive changes in the patient. true https://pubmed.ncbi.nlm.nih.gov/21514249/ Modified definition concern regarding a change in cognition A symptom that entails mild problems performing complex functional tasks which they used to perform previously, such as paying bills, preparing a meal, or shopping. The person requires more time, is less efficient, and makes more errors at performing such activities than in the past. Nevertheless, the person generally maintains their independence of function in daily life. true https://pubmed.ncbi.nlm.nih.gov/21514249/ preservation of independence in functional abilities A mental impairment in the ability to learn and retain new information, or recall information about a specific event that has occurred at a specific time and place. memory impairment true https://pubmed.ncbi.nlm.nih.gov/21514249/ Modified definition impairment in episodic memory episodic memory impairment A memory test that controls attention and acquisition, by providing category cues in the learning process. true https://pubmed.ncbi.nlm.nih.gov/25062746/ FCSRT Test Free and Cued Selective Reminding Test A measure of confrontation naming that takes into account the finding that patients with dysnomia often have greater difficulties with the naming of low frequency objects and consists of 60 black and white line drawings of objects https://link.springer.com/referenceworkentry/10.1007/978-0-387-79948-3_869#:~:text=The%20Boston%20Naming%20Test%20(BNT,naming%20of%20low%20frequency%20objects. BNT Test Boston Naming Test A short screening test that evaluates language skills and it consists of Semantic verbal Fluency Tests (SFT) and Categorical verbal Fluency Tests (CFT). https://www.frontiersin.org/articles/10.3389/fpsyg.2019.02797/full verbal fluency test category and letter verbal fluency test A testing tool that uses a variety of simple and informal techniques, performed by clinicians. For example, the clinician can ask a patient to learn a street address and to recall it after a delay interval of a few minutes. true https://pubmed.ncbi.nlm.nih.gov/21514249/ informal cognitive testing A clinical tool that measures and evaluates cognition of the patient with certain time intervals while maintaining the consistency in parameters employed in testing. https://www.sciencedirect.com/science/article/pii/S2352872918300824 longitudinal cognitive evaluation A type of dementia which which the person meets the core clinical creteria for probable Alzheimer dementia. probable Alzheimer dementia https://pubmed.ncbi.nlm.nih.gov/21514250/ A symptom with which a patient may misunderstand the motives of the actions of their family, friends or others true https://pubmed.ncbi.nlm.nih.gov/21514250/ impaired reasoning A symptom including defficulty thinking of common words while speaking, hesitations, speech, spelling, and writing errors. true https://pubmed.ncbi.nlm.nih.gov/21514250/ impaired language functions A stage where symptoms have a gradual onset over months to years but with harmful effects, not sudden within hours or days. https://pubmed.ncbi.nlm.nih.gov/9546336/ insidious onset of dementia A symptom including impairment in learning and recalling of recently learned information, loss of memory, disorientation with time and space, lack of insight to their memory loss and being aware of their memory loss but not being able to understand why. https://hospitals.aku.edu/pakistan/diseases-and-conditions/Pages/amnestic-disorder.aspx amnestic symptom A symptom that is sufficiently mild that there is no evidence of a significant impairment in social or occupational functioning. true https://pubmed.ncbi.nlm.nih.gov/21514249/ non-demented cognitive impairment A type of Alzheimer dementia whic meets core clinical criteria for possible Alzheimer dementia https://www.nia.nih.gov/health/alzheimers-disease-diagnostic-guidelines possible Alzheimer dementia A stage where cognitive impiarment suddenly arises https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331682/ sudden onset of cognitive impairment A biological process by which an individual has biomarker evidence of amyloid-beta accumulation with elevated tracer retention on PET amyloid imaging and/or low amyloid-beta 42 in CSF assay, but no detectable evidence of additional brain alterations suggestive of neurodegeneration or subtle cognitive and/or behavioral symptomatology. true https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220946/ asymptomatic cerebral amyloidosis A result from clinical assessment that characterizes presence of abnormal amyloid found with cerebrospinal fluid (CSF) and/or positron emission tomography (PET) https://pubmed.ncbi.nlm.nih.gov/25713403/ amyloid positivity A ratio between amyloid-beta 42 and amyloid-beta 40. Decreased ratio of amyloid-beta 42/40 is a strong marker of Alzheimer's disease. https://www.svarlifescience.com/services/wieslab-diagnostic-services/997-l-beta-amyloid-ratio-42-40#:~:text=Beta%20amyloid%2040%20is%20the,even%20before%20clinical%20dementia%20occurs. amyloid-beta 42/amyloid-beta 40 ratio A technique used to determine the specific apolipoprotein E (APOE) genotypes in patients with type III hyperlipoproteinemia APOE genotyping Apolipoprotein E Genotyping APOE genotype test https://www.mayocliniclabs.com/test-catalog/Overview/35358 An inhibitor that interferes the chemical reaction of BACE1 beta-site APP cleaving enzyme 1 inhibitor BACE1 inhibitor A measurement that quantifies the amount of beta-secretase 1 (BACE1) normally found in blood or cerebrospinal fluid. The quantification of the amount of beta-secretase 1 in a sample, typicallly cerebrospinal fluid. Beta-secretase-1 is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells, and is thought to have a role in Alzheimer's disease pathogenesis. Quantification of the amount of beta-secretase 1 in a sample, typicallly cerebrospinal fluid. Beta-secretase-1 is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells, and is thought to have a role in Alzheimer's disease pathogenesis. beta-secretase 1 measurement https://pubmed.ncbi.nlm.nih.gov/31745860/ A test developed from cognitive assessments on 406 normal subjects and 342 mild AD patients in the CERAD (Consortium to Establish a Registry for AD) dataset. true https://pubmed.ncbi.nlm.nih.gov/14646030/ BAS (Brief Alzheimer Screen) Screening Test Brief Alzheimer Screen test A tool to assess cognitive functions in diverse neurological and psychiatric disorders, such as dementia, schizophrenia, depression, Parkinson's Disease. https://pubmed.ncbi.nlm.nih.gov/16085791/ CANTAB-Alz Cambridge Neuropsychological Test Automated Battery for Alzheimer disease A behavior of consuming caffeine-containing products such as coffee, tea, cacao, energy drinks true https://pubmed.ncbi.nlm.nih.gov/8603790/ caffeine consumption A tool used as a new 6-8 minute dementia screening, consisting of 5 short subtests, which is objective both in performance and evaluation. https://www.researchgate.net/publication/285702266_DemTect_A_new_screening_method_to_support_diagnosis_of_dementia DemTect screening test A behavior of consuming tabacco products https://www.alzheimers.org.uk/about-dementia/risk-factors-and-prevention/smoking-and-dementia#:~:text=It%20is%20known%20that%20smoking,the%20development%20of%20Alzheimer's%20disease. tobacco consumption A questionnaire comprised of multiple subscales evaluating everyday cognitive function true https://pubmed.ncbi.nlm.nih.gov/18590364/ Ecog questionnaire Everyday Cognition questionnaire A method used for assessment of primary degenerative dementia and delineation of its stages true https://pubmed.ncbi.nlm.nih.gov/7114305/ GDS scale Global Deterioration Scale Traumatic brain injury usually results from a violent blow or jolt to the head or body. An object that goes through brain tissue, such as a bullet or shattered piece of skull, also can cause traumatic brain injury. https://www.mayoclinic.org/diseases-conditions/traumatic-brain-injury/symptoms-causes/syc-20378557 traumatic brain injury A symptom of failure to communicate with others. https://pubmed.ncbi.nlm.nih.gov/23522497/ Inability to communicate A cognitive symptom of failure to recognize oneself's or family member's identity https://pubmed.ncbi.nlm.nih.gov/22553492/ Inability to recognize oneself or family A test that separates normal from MCI and demented elders in a prevalence-stratified sample https://www.omicsonline.org/the-memory-orientation-screening-test-most-accurately-separates-normal-from-mci-and-demented-elders-in-a-prevalence-stratified-sample-2161-0460.1000109.php?aid=11372 MOST test Memory Orientation Screening Test A screening examination that assesses cognition in a brief but quantitative fashion, uses independent tests to evaluate functioning within five major cognitive ability areas: language, constructions, memory, calculations, and reasoning. true https://pubmed.ncbi.nlm.nih.gov/3631786/ NCSE Neurobehavioral Cognitive Status Examination A questionaire with 10 items that can be easily administered by clinicians in mental impairment diagnosis true https://pubmed.ncbi.nlm.nih.gov/1159263/ SPMSQ Short Portable Mental Status Questionnaire (SPMSQ) An acupuncture method that involves pucture at bilateral Yingxiang and Yintang points true https://pubmed.ncbi.nlm.nih.gov/21717774/ Xiusanzhen A protein that is regarded as a general marker of neurodegeneration for evaluation in future population-based studies and represents the total tau concentration in a given sample. https://pubmed.ncbi.nlm.nih.gov/15178952/ total tau A protein that is phosphorylated through post-translational modification. Its accumulation reflects the formation of neurofibrillary tangles, synaptic impairment, and neuronal dysfunction. https://pubmed.ncbi.nlm.nih.gov/32812023/ phosphorylated tau a signaling process that is initiated through binding and activation of its cell-surface receptor and initiates a cascade of phosphorylation and dephosphorylation events, second-messenger generation, and protein-protein interactions that result in diverse metabolic events in almost every tissue https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/insulin-signaling insulin signalling A signaling process through which neurotrophins modulate long-term potentiation, dendritic complexity and axon branching, processes that promote synaptic efficacy and thus learning and memory. true https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295469/ neurotrophic signalling An internal signaling process in response to extracellular signals through which phosphatidylinositols undergo rapid turnover and generate second messengers including diacylglycerol, inositol 1,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate (PtdIns 3,4P2) and phosphatidylinositol 3,4,5-trisphosphate. https://pubmed.ncbi.nlm.nih.gov/9599410 phospatidylinositol signalling entity Entity entity Julius Caesar Verdi’s Requiem the Second World War your body mass index BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81 Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) entity entity Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf per discussion with Barry Smith An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) continuant Continuant continuant An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240 Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] continuant Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] occurrent Occurrent BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players. Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] occurrent occurrent Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. per discussion with Barry Smith Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] ic IndependentContinuant a chair a heart a leg a molecule a spatial region an atom an orchestra. an organism the bottom right portion of a human torso the interior of your mouth b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] independent continuant b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] s-region SpatialRegion BFO 2 Reference: Spatial regions do not participate in processes. Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional. A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001]) All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001]) (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] spatial region Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional. per discussion with Barry Smith A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001]) All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001]) (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] t-region TemporalRegion Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001]) All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001]) Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002]) (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] temporal region Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional per discussion with Barry Smith A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001]) All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001]) Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002]) (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] 2d-s-region TwoDimensionalSpatialRegion an infinitely thin plane in space. the surface of a sphere-shaped part of space A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001]) (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] two-dimensional spatial region A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001]) (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] st-region SpatiotemporalRegion the spatiotemporal region occupied by a human life the spatiotemporal region occupied by a process of cellular meiosis. the spatiotemporal region occupied by the development of a cancer tumor A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001]) All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001]) Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001]) Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001]) Every spatiotemporal region occupies_spatiotemporal_region itself. Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002]) (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] spatiotemporal region A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001]) All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001]) Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001]) Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001]) Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002]) (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] process Process a process of cell-division, \ a beating of the heart a process of meiosis a process of sleeping the course of a disease the flight of a bird the life of an organism your process of aging. p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war) (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] process p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] disposition Disposition an atom of element X has the disposition to decay to an atom of element Y certain people have a predisposition to colon cancer children are innately disposed to categorize objects in certain ways. the cell wall is disposed to filter chemicals in endocytosis and exocytosis BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type. b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] disposition b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] realizable RealizableEntity the disposition of this piece of metal to conduct electricity. the disposition of your blood to coagulate the function of your reproductive organs the role of being a doctor the role of this boundary to delineate where Utah and Colorado meet A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] realizable entity To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] 0d-s-region ZeroDimensionalSpatialRegion A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001]) (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] zero-dimensional spatial region A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001]) (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] quality Quality the ambient temperature of this portion of air the color of a tomato the length of the circumference of your waist the mass of this piece of gold. the shape of your nose the shape of your nostril a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001]) If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001]) (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] quality a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001]) If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001]) (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] sdc SpecificallyDependentContinuant specifically dependent continuant Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key of one-sided specifically dependent continuants: the mass of this tomato of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates. the disposition of this fish to decay the function of this heart: to pump blood the mutual dependence of proton donors and acceptors in chemical reactions [79 the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction the pink color of a medium rare piece of grilled filet mignon at its center the role of being a doctor the shape of this hole. the smell of this portion of mozzarella A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] specifically dependent continuant (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. per discussion with Barry Smith role Role John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married. the priest role the role of a boundary to demarcate two neighboring administrative territories the role of a building in serving as a military target the role of a stone in marking a property boundary the role of subject in a clinical trial the student role BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives. b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001]) (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] role b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001]) (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] fiat-object-part FiatObjectPart or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29 the FMA:regional parts of an intact human body. the Western hemisphere of the Earth the division of the brain into regions the division of the planet into hemispheres the dorsal and ventral surfaces of the body the upper and lower lobes of the left lung BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004]) (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] fiat object part b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004]) (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] 1d-s-region OneDimensionalSpatialRegion an edge of a cube-shaped portion of space. A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001]) (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] one-dimensional spatial region A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001]) (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] object-aggregate ObjectAggregate a collection of cells in a blood biobank. a swarm of bees is an aggregate of members who are linked together through natural bonds a symphony orchestra an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team) defined by fiat: the aggregate of members of an organization defined through physical attachment: the aggregate of atoms in a lump of granite defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container defined via attributive delimitations such as: the patients in this hospital the aggregate of bearings in a constant velocity axle joint the aggregate of blood cells in your body the nitrogen atoms in the atmosphere the restaurants in Palo Alto your collection of Meissen ceramic plates. An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee). ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158. b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004]) (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] object aggregate An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158. b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004]) (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] 3d-s-region ThreeDimensionalSpatialRegion a cube-shaped region of space a sphere-shaped region of space, A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001]) (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] three-dimensional spatial region A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001]) (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] site Site Manhattan Canyon) a hole in the interior of a portion of cheese a rabbit hole an air traffic control region defined in the airspace above an airport the Grand Canyon the Piazza San Marco the cockpit of an aircraft the hold of a ship the interior of a kangaroo pouch the interior of the trunk of your car the interior of your bedroom the interior of your office the interior of your refrigerator the lumen of your gut your left nostril (a fiat part – the opening – of your left nasal cavity) b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002]) (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] site b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002]) (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] object Object atom cell cells and organisms engineered artifacts grain of sand molecule organelle organism planet solid portions of matter star BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting. BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below). BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47 BFO 2 Reference: an object is a maximal causally unified material entity BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74 b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001]) object b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001]) gdc GenericallyDependentContinuant The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity. the pdf file on your laptop, the pdf file that is a copy thereof on my laptop the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule. b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] generically dependent continuant b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] function Function the function of a hammer to drive in nails the function of a heart pacemaker to regulate the beating of a heart through electricity the function of amylase in saliva to break down starch into sugar BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc. A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001]) (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] function A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001]) (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] p-boundary ProcessBoundary the boundary between the 2nd and 3rd year of your life. p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]) Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002]) (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] process boundary p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]) Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002]) (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] 1d-t-region OneDimensionalTemporalRegion the temporal region during which a process occurs. BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks). A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001]) (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] one-dimensional temporal region A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001]) (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] material MaterialEntity a flame a forest fire a human being a hurricane a photon a puff of smoke a sea wave a tornado an aggregate of human beings. an energy wave an epidemic the undetached arm of a human being BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60 BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity. BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here. A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] bfo BFO:0000040 material entity material entity A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] cf-boundary ContinuantFiatBoundary b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001]) BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions. BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29 Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions. Every continuant fiat boundary is located at some spatial region at every time at which it exists (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] continuant fiat boundary b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001]) Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions. (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] immaterial ImmaterialEntity BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10 immaterial entity 1d-cf-boundary OneDimensionalContinuantFiatBoundary The Equator all geopolitical boundaries all lines of latitude and longitude the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin. the median sulcus of your tongue a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001]) (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] one-dimensional continuant fiat boundary a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001]) (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] process-profile ProcessProfile On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance. The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on. b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002]) b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005]) (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] process profile b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002]) b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005]) (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] r-quality RelationalQuality John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married. a marriage bond, an instance of requited love, an obligation between one person and another. b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001]) (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] relational quality b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001]) (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] 2d-cf-boundary TwoDimensionalContinuantFiatBoundary a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001]) (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] two-dimensional continuant fiat boundary a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001]) (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] 0d-cf-boundary ZeroDimensionalContinuantFiatBoundary the geographic North Pole the point of origin of some spatial coordinate system. the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona. a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001]) (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] zero-dimensional continuant fiat boundary zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona. requested by Melanie Courtot a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001]) (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] 0d-t-region ZeroDimensionalTemporalRegion a temporal region that is occupied by a process boundary right now the moment at which a child is born the moment at which a finger is detached in an industrial accident the moment of death. temporal instant. A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001]) (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] zero-dimensional temporal region A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001]) (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] Cells taken from a living organism and grown under controlled conditions (in culture). Methods used to maintain cell lines or strains. BrendaTissueOBO BTO:0000214 cell culture Neuroglial cells of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. Originally, the term was used for the astrocytes alone. BrendaTissueOBO macroglial cell BTO:0000771 macroglia BrendaTissueOBO NBL cell line BTO:0000932 neuroblastoma cell line Any of a kingdom (Plantae) of living things typically lacking locomotive movement or obvious nervous or sensory organs and possessing cellulose cell walls. BrendaTissueOBO Pflanze plantae viridiplantae BTO:0001481 plant Mus musculus (mouse) brain neuroblastoma cell line. Clone Neuro-2a was established by R.J. Klebe and F.H. Ruddle from a spontaneous tumor of a strain A albino mouse. BrendaTissueOBO N-2a cell N2A cell N2a cell N2alpha cell NB-2a cell NB2a cell NEURO-2A cell Nb2a cell Neuro 2A cell Neuro2A cell Neuro2a cell BTO:0001976 Neuro-2a cell A serrated strip of gray matter under the medial border of the hippocampus and in its depths; it is an archaeocortex which develops along the edge of the hippocampal fissure and which consists of molecular, granular, and polymorphic layers. BrendaTissueOBO gyrus dentatus hippocampal dentate gyrus BTO:0002496 dentate gyrus A plaque consisting of tangles of amyloid protein in nervous tissue (a pathological mark of Alzheimer's disease). BrendaTissueOBO BTO:0002774 amyloid plaque The medial temporal lobes are near the Sagittal plane that divides left and right cerebral hemispheres and are thought to be involved in episodic, declarative memory. Marion 2010-02-04T10:57:44Z BrendaTissueOBO BTO:0004477 medial temporal lobe A piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms. 0 C21H21ClN4OS InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 412.93600 412.11246 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 Beilstein:6669199 CAS:146939-27-7 DrugBank:DB00246 Drug_Central:2865 KEGG:C07568 KEGG:D08687 LINCS:LSM-5433 Patent:EP281309 Patent:US4831031 Wikipedia:Ziprasidone 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one Ziprasidone chebi_ontology ziprasidona ziprasidone ziprasidonum CHEBI:10119 ziprasidone Any member of a group of fat-soluble retinoids produced via metabolism of provitamin A carotenoids that exhibit biological activity against vitamin A deficiency. Vitamin A is involved in immune function, vision, reproduction, and cellular communication. MetaCyc:Vitamin-A Wikipedia:Vitamin_A chebi_ontology vitamin A vitamer vitamin A vitamers vitamin-A vitamins A CHEBI:12777 vitamin A Any oxygenated derivative of C22 polyunsaturated fatty acids, such as docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA). chebi_ontology docosanoids CHEBI:131863 docosanoid 0 C19H23NO3 InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3/t18-,19-/m1/s1 CBQGYUDMJHNJBX-RTBURBONSA-N 313.392 313.16779 [C@](OC1=C(OCC)C=CC=C1)(C2=CC=CC=C2)([C@]3(CNCCO3)[H])[H] CAS:71620-89-8 Drug_Central:2361 chebi_ontology edronax norebox reboxetine mesilate reboxetine mesylate reboxitine CHEBI:135342 reboxetine 0 C22H30N2O5S2 InChI=1S/C22H30N2O5S2/c1-3-29-21(28)17(10-9-16-7-5-4-6-8-16)23-15(2)19(25)24-14-22(30-11-12-31-22)13-18(24)20(26)27/h4-8,15,17-18,23H,3,9-14H2,1-2H3,(H,26,27)/t15-,17-,18-/m0/s1 HRWCVUIFMSZDJS-SZMVWBNQSA-N 466.617 466.15961 C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2CC3(C[C@H]2C(=O)O)SCCS3 CAS:83647-97-6 DrugBank:DB01348 Drug_Central:2474 HMDB:HMDB0015438 KEGG:D08529 PMID:10499560 PMID:10499561 PMID:12613273 PMID:8638865 PMID:9345854 Reaxys:4277924 Wikipedia:Spirapril (8S)-7-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid chebi_ontology CHEBI:135756 spirapril A 3-oxo monocarboxylic acid anion that is the conjugate base of acetoacetic acid, arising from deprotonation of the carboxy group. -1 C4H5O3 InChI=1S/C4H6O3/c1-3(5)2-4(6)7/h2H2,1H3,(H,6,7)/p-1 WDJHALXBUFZDSR-UHFFFAOYSA-M 101.08070 101.02442 CC(=O)CC([O-])=O Beilstein:4128534 CAS:141-81-1 KEGG:C00164 MetaCyc:3-KETOBUTYRATE Reaxys:4128534 UM-BBD_compID:c0069 3-oxobutanoate Acetoacetate acetoacetate chebi_ontology Acetoacetate ion(1-) Butanoic acid, 3-oxo-, ion(1-) CHEBI:13705 acetoacetate A dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13E,15Z,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10R,17S-stereoisomer). Protectin D1 is one of the specialised proresolving mediators. When produced in neural tissues, it is called neuroprotectin D1 0 C22H32O4 InChI=1S/C22H32O4/c1-2-3-10-15-20(23)17-12-8-9-13-18-21(24)16-11-6-4-5-7-14-19-22(25)26/h3,5-13,17-18,20-21,23-24H,2,4,14-16,19H2,1H3,(H,25,26)/b7-5-,9-8+,10-3-,11-6-,17-12-,18-13+/t20-,21+/m0/s1 CRDZYJSQHCXHEG-SFVBTVKNSA-N 360.488 360.23006 OC(CC/C=C\C/C=C\C[C@H](\C=C\C=C\C=C/[C@H](C/C=C\CC)O)O)=O Alzpathway: NPD1 leading to ADAM10; Source: https://pubmed.ncbi.nlm.nih.gov/21431475/ HMDB:HMDB0003689 PMID:22690022 PMID:23686636 PMID:23799606 PMID:24107502 PMID:24262603 PMID:24520010 PMID:25139562 PMID:25617763 PMID:26047923 PMID:26427436 PMID:26580578 PMID:26955849 PMID:27632672 PMID:27866493 PMID:27988338 PMID:28109294 PMID:28429196 PMID:28430183 PMID:28615451 PMID:29177613 Reaxys:18351330 Wikipedia:Protectin_D1 (4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid chebi_ontology (4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxydocosahexaenoic acid (N)PD1 (neuro)protectin D1 10(R),17(S)-dihydroxydocosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid NPD1 PD1 neuroprotectin D1 CHEBI:138655 protectin D1 A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1). 0 CHNOR2 43.025 43.00581 N(C(*)=O)(*)[H] chebi_ontology secondary carboxamides CHEBI:140325 secondary carboxamide A monounsaturated fatty aldehyde that is nonanal that has undergone dehydrogenation to introduce a double bond at any position in the aliphatic chain and in which a hydrogen at position 4 has been replaced by a hydroxy group. 0 C9H16O2 156.222 156.11503 *C([H])=O PMID:15865448 chebi_ontology a 4-hydroxynonenal CHEBI:142593 4-hydroxynonenal A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the beta cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies. PMID:12137720 PMID:19251032 PMID:25848166 PMID:5941964 PMID:6069707 Wikipedia:Insulin chebi_ontology CHEBI:145810 insulin A 3-oxoacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of acetoacetic acid. 0 C25H40N7O18P3S InChI=1S/C25H40N7O18P3S/c1-13(33)8-16(35)54-7-6-27-15(34)4-5-28-23(38)20(37)25(2,3)10-47-53(44,45)50-52(42,43)46-9-14-19(49-51(39,40)41)18(36)24(48-14)32-12-31-17-21(26)29-11-30-22(17)32/h11-12,14,18-20,24,36-37H,4-10H2,1-3H3,(H,27,34)(H,28,38)(H,42,43)(H,44,45)(H2,26,29,30)(H2,39,40,41)/t14-,18-,19-,20+,24-/m1/s1 OJFDKHTZOUZBOS-CITAKDKDSA-N 851.610 851.13634 CC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N CHEBI:11756 CHEBI:13706 CHEBI:22173 CHEBI:2392 CHEBI:41333 CAS:1420-36-6 DrugBank:DB03059 FooDB:FDB022648 HMDB:HMDB0001484 KEGG:C00332 KNApSAcK:C00007269 LIPID_MAPS_instance:LMFA07050030 PDBeChem:CAA PMID:10806397 PMID:11137815 PMID:11451959 PMID:12501183 PMID:1682408 PMID:16887802 PMID:239468 PMID:24211201 PMID:26527136 PMID:27093562 PMID:27124816 PMID:28062645 PMID:29226071 PMID:32218776 PMID:6118268 PMID:6150478 PMID:7857927 Reaxys:78273 UM-BBD_compID:c0229 Wikipedia:Acetoacetyl-CoA 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(3-oxobutanoyl)sulfanyl]ethyl}amino)propyl]amino}butyl] dihydrogen diphosphate} Acetoacetyl-CoA chebi_ontology 3-Acetoacetyl-CoA Acetoacetyl coenzyme A S-Acetoacetyl-coenzym A S-acetoacetyl-CoA S-acetoacetyl-coenzyme A acetoacetyl CoA CHEBI:15345 acetoacetyl-CoA A thiol comprising a panthothenate unit in phosphoric anhydride linkage with a 3',5'-adenosine diphosphate unit; and an aminoethanethiol unit. 0 C21H36N7O16P3S InChI=1S/C21H36N7O16P3S/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35)/t11-,14-,15-,16+,20-/m1/s1 RGJOEKWQDUBAIZ-IBOSZNHHSA-N 767.53540 767.11521 CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS CHEBI:13294 CHEBI:13295 CHEBI:13298 CHEBI:23355 CHEBI:3771 CHEBI:41597 CHEBI:41631 CHEBI:741566 Beilstein:77809 CAS:85-61-0 DrugBank:DB01992 KEGG:C00010 KNApSAcK:C00007258 PDBeChem:COA PDBeChem:COZ PMID:11923312 PMID:13025483 PMID:15014152 PMID:15893380 PMID:18407920 PMID:19666462 PMID:20351285 PMID:2981478 PMID:7310833 Wikipedia:Coenzyme_A 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl] dihydrogen diphosphate} COENZYME A Coenzyme A chebi_ontology 3'-phosphoadenosine-(5')diphospho(4')pantatheine CoA CoA-SH CoASH Coenzym A HSCoA Koenzym A [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate CHEBI:15346 coenzyme A An acyl-CoA having acetyl as its S-acetyl component. 0 C23H38N7O17P3S InChI=1S/C23H38N7O17P3S/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38)/t13-,16-,17-,18+,22-/m1/s1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 809.57208 809.12577 CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12 CHEBI:13712 CHEBI:22192 CHEBI:2408 CHEBI:40470 CAS:72-89-9 ECMDB:ECMDB01206 HMDB:HMDB0001206 KEGG:C00024 KNApSAcK:C00007259 PDBeChem:ACO PMID:12527305 PMID:12739170 PMID:15247244 PMID:16101314 PMID:16667687 PMID:16708165 PMID:17189273 PMID:17242360 PMID:17631502 PMID:18613815 PMID:19356710 PMID:19596230 PMID:19914586 PMID:3950616 Reaxys:78145 UM-BBD_compID:c0031 Wikipedia:Acetyl-CoA YMDB:YMDB00312 3'-phosphoadenosine 5'-(3-{(3R)-4-[(3-{[2-(acetylsulfanyl)ethyl]amino}-3-oxopropyl)amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl} dihydrogen diphosphate) Acetyl-CoA chebi_ontology AcCoA Acetyl coenzyme A S-acetyl-CoA S-acetyl-coenzyme A CHEBI:15351 acetyl-CoA A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. +1 C5H14NO InChI=1S/C5H14NO/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3/q+1 OEYIOHPDSNJKLS-UHFFFAOYSA-N 104.17080 104.10699 C[N+](C)(C)CCO CHEBI:13985 CHEBI:23212 CHEBI:3665 CHEBI:41524 Beilstein:1736748 CAS:62-49-7 DrugBank:DB00122 Drug_Central:3097 ECMDB:ECMDB00097 Gmelin:324597 HMDB:HMDB0000097 KEGG:C00114 KEGG:D07690 KNApSAcK:C00007298 MetaCyc:CHOLINE PDBeChem:CHT PMID:10930630 PMID:12826235 PMID:12946691 PMID:14972364 PMID:16210714 PMID:17087106 PMID:17283071 PMID:17344490 PMID:18204095 PMID:18230680 PMID:18786517 PMID:18786520 PMID:19246089 PMID:20038853 PMID:20446114 PMID:22770225 PMID:22961562 PMID:23095202 PMID:23616508 PMID:23637565 PMID:23733158 PMID:6420466 PMID:7590654 PMID:9517478 Reaxys:1736748 Wikipedia:Choline YMDB:YMDB00227 2-hydroxy-N,N,N-trimethylethanaminium Choline choline chebi_ontology Bilineurine CHOLINE ION N,N,N-trimethylethanol-ammonium N-trimethylethanolamine trimethylethanolamine CHEBI:15354 choline Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter. +1 C7H16NO2 InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1 OIPILFWXSMYKGL-UHFFFAOYSA-N 146.20748 146.11756 CC(=O)OCC[N+](C)(C)C CHEBI:12686 CHEBI:13715 CHEBI:22197 CHEBI:2416 CHEBI:40559 Beilstein:1764436 CAS:51-84-3 DrugBank:DB03128 Drug_Central:65 Gmelin:326108 KEGG:C01996 LINCS:LSM-5888 PDBeChem:ACH PMID:14764638 PMID:15014918 PMID:15231705 PMID:15361288 PMID:18050502 PMID:18407448 PMID:19255787 PMID:20963497 PMID:21130809 PMID:21246223 PMID:21545631 PMID:21601579 Wikipedia:Acetylcholine 2-acetyloxy-N,N,N-trimethylethanaminium ACETYLCHOLINE Acetylcholine acetylcholine chebi_ontology ACh Azetylcholin O-Acetylcholine choline acetate CHEBI:15355 acetylcholine A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. 0 C3H7NO2S InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6) XUJNEKJLAYXESH-UHFFFAOYSA-N 121.15922 121.01975 NC(CS)C(O)=O CHEBI:14061 CHEBI:23508 CHEBI:4050 Beilstein:1721406 CAS:3374-22-9 Gmelin:2933 KEGG:C00736 KNApSAcK:C00001351 KNApSAcK:C00007323 PMID:17439666 PMID:25181601 Reaxys:1721406 Wikipedia:Cysteine Cysteine cysteine chebi_ontology 2-Amino-3-mercaptopropionic acid 2-amino-3-mercaptopropanoic acid 2-amino-3-sulfanylpropanoic acid C Cys Cystein Hcys Zystein cisteina CHEBI:15356 cysteine A 2-oxo monocarboxylic acid anion that is the conjugate base of pyruvic acid, arising from deprotonation of the carboxy group. -1 C3H3O3 InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)/p-1 LCTONWCANYUPML-UHFFFAOYSA-M 87.05412 87.00877 CC(=O)C([O-])=O CHEBI:14987 CHEBI:26462 Beilstein:3587721 CAS:57-60-3 Gmelin:2502 KEGG:C00022 PMID:17190852 PMID:21603897 PMID:21823181 PMID:21854850 PMID:22006570 PMID:22016370 PMID:22215378 PMID:22311625 PMID:22451307 PMID:22458763 Reaxys:3587721 UM-BBD_compID:c0159 2-oxopropanoate pyruvate chebi_ontology 2-oxopropanoate 2-oxopropanoic acid, ion(1-) CHEBI:15361 pyruvate An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms. 0 H2O InChI=1S/H2O/h1H2 XLYOFNOQVPJJNP-UHFFFAOYSA-N 18.01530 18.01056 [H]O[H] CHEBI:10743 CHEBI:13352 CHEBI:27313 CHEBI:42043 CHEBI:42857 CHEBI:43228 CHEBI:44292 CHEBI:44701 CHEBI:44819 CHEBI:5585 Beilstein:3587155 CAS:7732-18-5 Gmelin:117 HMDB:HMDB0002111 KEGG:C00001 KEGG:D00001 MetaCyc:WATER MolBase:1 PDBeChem:HOH Reaxys:3587155 Wikipedia:Water WATER Water oxidane water chebi_ontology BOUND WATER H2O HOH Wasser [OH2] acqua agua aqua dihydridooxygen dihydrogen oxide eau hydrogen hydroxide CHEBI:15377 water An omega-carboxyacyl-CoA having succinoyl as the S-acyl component. 0 C25H40N7O19P3S InChI=1S/C25H40N7O19P3S/c1-25(2,20(38)23(39)28-6-5-14(33)27-7-8-55-16(36)4-3-15(34)35)10-48-54(45,46)51-53(43,44)47-9-13-19(50-52(40,41)42)18(37)24(49-13)32-12-31-17-21(26)29-11-30-22(17)32/h11-13,18-20,24,37-38H,3-10H2,1-2H3,(H,27,33)(H,28,39)(H,34,35)(H,43,44)(H,45,46)(H2,26,29,30)(H2,40,41,42)/t13-,18-,19-,20+,24-/m1/s1 VNOYUJKHFWYWIR-ITIYDSSPSA-N 867.60816 867.13125 CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCC(O)=O CHEBI:10746 CHEBI:15127 CHEBI:26811 CHEBI:45541 CHEBI:9310 CAS:604-98-8 DrugBank:DB03699 KEGG:C00091 KNApSAcK:C00019546 PDBeChem:SCA PMID:15627487 PMID:17259607 PMID:38930 PMID:7462221 Reaxys:78365 UM-BBD_compID:c0344 3'-phosphoadenosine 5'-{3-[(3R)-4-{[3-({2-[(3-carboxypropanoyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate} Succinyl-CoA succinyl-CoA chebi_ontology Coenzyme A, S-(hydrogen butanedioate) S-(3-Carboxy-propionyl)-coenzym-A S-(3-carboxy-propionyl)-CoA S-(3-carboxypropionyl)-coenzyme-A S-(Hydrogen succinyl)coenzyme A S-(hydrogen succinyl)-CoA SUCCINYL-COENZYME A Succinyl coenzyme A Succinyl-coenzyme A CHEBI:15380 succinyl-CoA A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration. 0 C30H50 InChI=1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+ YYGNTYWPHWGJRM-AAJYLUCBSA-N 410.730 410.39125 CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CCC=C(C)C CHEBI:10795 CHEBI:10843 CHEBI:15104 CHEBI:26746 CHEBI:9245 Beilstein:1728920 CAS:111-02-4 HMDB:HMDB0000256 KEGG:C00751 KNApSAcK:C00003755 LIPID_MAPS_instance:LMPR0106010002 MetaCyc:SQUALENE PDBeChem:SQL PMID:16341241 PMID:23625688 PMID:24362891 PMID:25286851 PMID:25286853 PMID:25987292 Wikipedia:Squalene (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Squalene squalene chebi_ontology (all-E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene Spinacene Supraene CHEBI:15440 squalene Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins. 0 C20H32O5 InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 XEYBRNLFEZDVAW-ARSRFYASSA-N 352.471 352.22497 CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O CHEBI:10910 CHEBI:10911 CHEBI:114125 CHEBI:26323 CHEBI:4625 CHEBI:8512 Beilstein:2224724 CAS:363-24-6 DrugBank:DB00917 Drug_Central:913 FooDB:FDB022498 HMDB:HMDB0001220 KEGG:C00584 KEGG:D00079 LINCS:LSM-42919 LIPID_MAPS_instance:LMFA03010003 PDBeChem:P2E PMID:11279302 PMID:12746806 PMID:12859290 PMID:14499495 PMID:14535055 PMID:14703707 PMID:15542928 PMID:15661432 PMID:16405508 PMID:16787416 PMID:16978535 PMID:20671299 PMID:2403792 PMID:24501112 PMID:32898608 PMID:33271839 PMID:33559528 PMID:33685091 PMID:33715333 PMID:33782420 PMID:33811074 PMID:33958485 PMID:34065827 PMID:34071686 PMID:34102274 PMID:6317292 PMID:7224729 PMID:74611 PMID:7836930 PMID:9276764 Patent:DE2011969 Patent:GB851827 Patent:NL6505799 Patent:US3598858 Reaxys:2224724 Wikipedia:Prostaglandin_E2 (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid Prostaglandin E2 chebi_ontology (15S)-prostaglandin E2 (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid Cervidil Cerviprime Cerviprost Dinoproston Enzaprost E Glandin-E2 Minprositin E2 Minprostin E2 PGE2 Prepidil Propess Prostarmon E Prostenone Prostin Prostin E2 U 12062 U-12,062 U-12062 dinoprostona dinoprostone dinoprostonum CHEBI:15551 prostaglandin E2 0 C20H32O5 InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18-14-19(17)25-24-18)10-7-4-5-8-11-20(22)23/h4,7,12-13,15-19,21H,2-3,5-6,8-11,14H2,1H3,(H,22,23)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 YIBNHAJFJUQSRA-YNNPMVKQSA-N 352.46508 352.22497 CCCCC[C@H](O)\C=C\[C@H]1[C@H]2C[C@H](OO2)[C@@H]1C\C=C/CCCC(O)=O CHEBI:10914 CHEBI:14909 CHEBI:26330 CHEBI:8520 Beilstein:1598632 CAS:42935-17-1 KEGG:C00427 LIPID_MAPS_instance:LMFA03010010 (5Z)-7-{(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid (5Z,13E,15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoic acid Prostaglandin H2 chebi_ontology (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate (5Z,13E,15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate (5Z,9alpha,11alpha,13E,15S)-9,11-epidioxy-15-hydroxyprosta-5,13-dien-1-oic acid 9,11-Epoxymethano-pgh2 PGH2 CHEBI:15554 prostaglandin H2 0 C20H25N7O6 InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12-,13-/m0/s1 ZNOVTXRBGFNYRX-STQMWFEESA-N 459.45580 459.18663 CN1[C@@H](CNc2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2nc(N)[nH]c(=O)c12 CHEBI:12146 CHEBI:2097 CAS:134-35-0 DrugBank:DB04789 KEGG:C00440 KNApSAcK:C00007252 N-[4-({[(6S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid chebi_ontology 5-Methyltetrahydrofolate N-(5-methyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid [(6S)-5-methyl-5,6,7,8-tetrahydropteroyl]glutamate CHEBI:15641 5-methyltetrahydrofolic acid An N-acyl-D-glucosamine 6-phosphate that is the N-acetyl derivative of D-glucosamine 6-phosphate. It is a component of the aminosugar metabolism. 0 C8H16NO9P InChI=1S/C8H16NO9P/c1-3(10)9-5-7(12)6(11)4(18-8(5)13)2-17-19(14,15)16/h4-8,11-13H,2H2,1H3,(H,9,10)(H2,14,15,16)/t4-,5-,6-,7-,8?/m1/s1 BRGMHAYQAZFZDJ-RTRLPJTCSA-N 301.18774 301.05627 CC(=O)N[C@H]1C(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O CHEBI:12456 CHEBI:12564 CHEBI:21521 CHEBI:7127 DrugBank:DB03951 HMDB:HMDB0001062 KEGG:C00357 KNApSAcK:C00019661 PMID:17077487 PMID:8125098 PMID:8747459 Reaxys:2337906 2-acetamido-2-deoxy-D-glucopyranose 6-(dihydrogen phosphate) N-Acetyl-D-glucosamine 6-phosphate N-acetyl-D-glucosamine 6-phosphate chebi_ontology 2-acetamido-2-deoxy-6-O-phosphono-D-glucopyranose CHEBI:15784 N-acetyl-D-glucosamine 6-phosphate A peptide containing ten or more amino acid residues. C4H6N2O3R2(C2H2NOR)n CHEBI:14860 CHEBI:8314 KEGG:C00403 Polypeptide polypeptides chebi_ontology Polypeptid polipeptido CHEBI:15841 polypeptide A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14. 0 C20H32O2 InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- YZXBAPSDXZZRGB-DOFZRALJSA-N 304.46690 304.24023 CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O CHEBI:22608 CHEBI:2799 CHEBI:40501 Beilstein:1913991 CAS:506-32-1 DrugBank:DB04557 Gmelin:58972 HMDB:HMDB0001043 KEGG:C00219 KNApSAcK:C00000388 LIPID_MAPS_instance:LMFA01030001 MetaCyc:ARACHIDONIC_ACID PDBeChem:ACD PMID:15129302 PMID:18931599 PMID:18973997 PMID:25584012 PMID:2820055 Reaxys:1913991 Wikipedia:Arachidonic_acid (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid ARACHIDONIC ACID Arachidonic acid chebi_ontology (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoic acid (5Z,8Z,11Z,14Z)-Icosatetraenoic acid AA ARA Arachidonate Arachidonsaeure all-cis-5,8,11,14-eicosatetraenoic acid cis-5,8,11,14-Eicosatetraenoic acid cis-Delta(5,8,11,14)-eicosatetraenoic acid CHEBI:15843 arachidonic acid The oxidised form of nicotinamide adenine dinucleotide found in all living cells. In metabolism, NAD(+) is involved in redox reactions, carrying electrons from one reaction to another. +1 C21H28N7O14P2 InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 BAWFJGJZGIEFAR-NNYOXOHSSA-O 664.43332 664.11640 NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O CHEBI:13394 CHEBI:21901 CHEBI:7422 Beilstein:4120619 CAS:53-84-9 COMe:MOL000026 DrugBank:DB01907 ECMDB:ECMDB00902 Gmelin:544242 HMDB:HMDB0000902 KEGG:C00003 KEGG:D00002 KNApSAcK:C00007256 LINCS:LSM-4965 PDBeChem:NAJ Reaxys:3584133 YMDB:YMDB00110 adenosine 5'-{3-[1-(3-carbamoylpyridinio)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate} chebi_ontology DPN Diphosphopyridine nucleotide NAD NAD+ Nadide Nicotinamide adenine dinucleotide beta-NAD CHEBI:15846 NAD(+) An amino sulfonic acid that is the 2-amino derivative of ethanesulfonic acid. It is a naturally occurring amino acid derived from methionine and cysteine metabolism. An abundant component of fish- and meat-based foods, it has been used as an oral supplement in the treatment of disorders such as cystic fibrosis and hypertension. 0 C2H7NO3S InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6) XOAAWQZATWQOTB-UHFFFAOYSA-N 125.148 125.01466 C(CS(O)(=O)=O)N CHEBI:15195 CHEBI:26852 CHEBI:45877 CHEBI:9406 Beilstein:1751215 CAS:107-35-7 DrugBank:DB01956 Drug_Central:4486 Gmelin:82121 HMDB:HMDB0000251 KEGG:C00245 KEGG:D00047 KNApSAcK:C00048188 MetaCyc:TAURINE PDBeChem:TAU PMID:10098958 PMID:10325611 PMID:10349454 PMID:10827156 PMID:11162030 PMID:11842876 PMID:11918831 PMID:11931837 PMID:12297216 PMID:12499349 PMID:12834252 PMID:14992292 PMID:15503229 PMID:15780050 PMID:15911239 PMID:16169526 PMID:16444816 PMID:16923232 PMID:17053427 PMID:17081118 PMID:17875433 PMID:17997039 PMID:18060526 PMID:18171928 PMID:19074966 PMID:19212411 PMID:19309105 PMID:19940987 PMID:2122710 PMID:21761941 PMID:22770225 PMID:2370482 PMID:24027187 PMID:2494044 PMID:27291853 PMID:27334436 PMID:27345710 PMID:27380030 PMID:27412799 PMID:27471162 PMID:27535560 PMID:3106924 PMID:3393260 PMID:6198473 PMID:7588651 PMID:8692051 PMID:8818047 PMID:9635063 Reaxys:1751215 Wikipedia:Taurine 2-aminoethanesulfonic acid Taurine chebi_ontology 2-Aminoethanesulfonic acid 2-aminoethyl sulfonate Aminoethylsulfonic acid beta-aminoethylsulfonic acid CHEBI:15891 taurine The 5-diphospho derivative of (R)-mevalonic acid. 0 C6H14O10P2 InChI=1S/C6H14O10P2/c1-6(9,4-5(7)8)2-3-15-18(13,14)16-17(10,11)12/h9H,2-4H2,1H3,(H,7,8)(H,13,14)(H2,10,11,12)/t6-/m1/s1 SIGQQUBJQXSAMW-ZCFIWIBFSA-N 308.11690 308.00622 C[C@@](O)(CCOP(O)(=O)OP(O)(O)=O)CC(O)=O CHEBI:10989 CHEBI:18674 CHEBI:332 KEGG:C01143 KNApSAcK:C00007615 PDBeChem:DP6 (3R)-3-hydroxy-5-{[hydroxy(phosphonooxy)phosphoryl]oxy}-3-methylpentanoic acid chebi_ontology (R)-5-Diphosphomevalonate (R)-5-diphosphomevalonate CHEBI:15899 (R)-5-diphosphomevalonic acid A class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxy group of ethanolamine. 0 C7H12NO8PR2 269.146 269.03005 O(P(=O)(OCCN)O)CC(OC(*)=O)COC(*)=O CHEBI:12701 CHEBI:14803 CHEBI:26030 CHEBI:26031 CHEBI:7661 CHEBI:8129 DrugBank:DB04327 HMDB:HMDB0060501 KEGG:C00350 LIPID_MAPS_instance:LMGP02010000 PMID:10540156 PMID:11042504 PMID:11159918 PMID:11829744 PMID:12139474 PMID:15653902 PMID:16037249 PMID:16303767 PMID:16620109 PMID:18034796 PMID:18259190 PMID:18398168 PMID:18462396 PMID:18570887 PMID:18957134 PMID:19393163 PMID:23354482 PMID:23369752 PMID:23543734 PMID:3196084 PMID:7980848 Wikipedia:Phosphatidylethanolamine Phosphatidylethanolamine phosphatidyl(amino)ethanols phosphatidylethanolamines chebi_ontology (3-Phosphatidyl)-ethanolamine (3-Phosphatidyl)ethanolamine 1,2-diacyl-sn-glycero-3-phosphoethanolamine 1-Acyl-2-acyl-sn-glycero-3-phosphoethanolamine Cephalin O-(1-beta-Acyl-2-acyl-sn-glycero-3-phospho)ethanolamine PE PtdEtn phosphatidylethanolamines CHEBI:16038 phosphatidylethanolamine Any one of a group of prenol derivatives made up of varying numbers of cis-linked isoprene units, terminating in an alpha-saturated isoprenoid group containing an alcohol functional group, with the three isoprene units at the distal end trans-linked. 0 (C5H8)nC20H36O CHEBI:14190 CHEBI:23877 CHEBI:4686 CHEBI:57636 CHEBI:67131 KEGG:C00381 PMID:12702274 PMID:14739709 PMID:20637498 PMID:21570481 PMID:22717794 PMID:23059969 PMID:8486680 Dolichol alpha-(4-hydroxy-2-methylbutyl)-omega-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]poly[(2Z)-2-methylbut-2-ene-1,4-diyl] dolichol chebi_ontology 2,3-dihydropolyprenol dolichols CHEBI:16091 dolichol A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group. 0 C27H46O InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1 HVYWMOMLDIMFJA-DPAQBDIFSA-N 386.655 386.35487 C1[C@@]2([C@]3(CC[C@]4([C@]([C@@]3(CC=C2C[C@H](C1)O)[H])(CC[C@@]4([C@H](C)CCCC(C)C)[H])[H])C)[H])C Alzpathway: APOE-cholesterol transport. Source: https://pubmed.ncbi.nlm.nih.gov/23620513/ CHEBI:13982 CHEBI:23204 CHEBI:3659 CHEBI:41564 Beilstein:2060565 CAS:57-88-5 DrugBank:DB04540 Gmelin:550297 HMDB:HMDB0000067 KEGG:C00187 KEGG:D00040 KNApSAcK:C00003648 LIPID_MAPS_instance:LMST01010001 MetaCyc:CHOLESTEROL PDBeChem:CLR PMID:10901445 PMID:11412894 PMID:16341241 PMID:24287311 PMID:25308664 PMID:25451949 PMID:25522988 PMID:25658343 PMID:25977713 PMID:4696527 PMID:8838010 Reaxys:2060565 Wikipedia:Cholesterol CHOLESTEROL Cholesterol cholest-5-en-3beta-ol cholesterol chebi_ontology (3beta,14beta,17alpha)-cholest-5-en-3-ol Cholest-5-en-3beta-ol Cholesterin CHEBI:16113 cholesterol A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid. -2 O4S InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2 QAOWNCQODCNURD-UHFFFAOYSA-L 96.06360 95.95283 [O-]S([O-])(=O)=O CHEBI:15135 CHEBI:45687 CHEBI:9335 Beilstein:3648446 CAS:14808-79-8 Gmelin:2120 HMDB:HMDB0001448 KEGG:C00059 KEGG:D05963 MetaCyc:SULFATE PDBeChem:SO4 PMID:11200094 PMID:11452993 PMID:11581495 PMID:11798107 PMID:12166931 PMID:12668033 PMID:14597181 PMID:15093386 PMID:15984785 PMID:16186560 PMID:16345535 PMID:16347366 PMID:16348007 PMID:16483812 PMID:16534979 PMID:16656509 PMID:16742508 PMID:16742518 PMID:17120760 PMID:17420092 PMID:17439666 PMID:17709180 PMID:18398178 PMID:18815700 PMID:18846414 PMID:19047345 PMID:19244483 PMID:19544990 PMID:19628332 PMID:19812358 PMID:30398859 Reaxys:3648446 Wikipedia:Sulfate Sulfate sulfate tetraoxidosulfate(2-) tetraoxosulfate(2-) tetraoxosulfate(VI) chebi_ontology SO4(2-) SULFATE ION Sulfate anion(2-) Sulfate dianion Sulfate(2-) Sulfuric acid ion(2-) [SO4](2-) sulphate sulphate ion CHEBI:16189 sulfate An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond. 0 H2O2 InChI=1S/H2O2/c1-2/h1-2H MHAJPDPJQMAIIY-UHFFFAOYSA-N 34.01468 34.00548 [H]OO[H] CHEBI:13354 CHEBI:13355 CHEBI:24637 CHEBI:44812 CHEBI:5586 Beilstein:3587191 CAS:7722-84-1 Drug_Central:3281 Gmelin:509 HMDB:HMDB0003125 KEGG:C00027 KEGG:D00008 MetaCyc:HYDROGEN-PEROXIDE MolBase:932 PDBeChem:PEO PMID:10455187 PMID:10557015 PMID:10849784 PMID:11033421 PMID:11105916 PMID:11318558 PMID:11387393 PMID:11809417 PMID:11864786 PMID:11893576 PMID:12867293 PMID:12934880 PMID:14679422 PMID:15028418 PMID:15133946 PMID:15298493 PMID:16337875 PMID:16463018 PMID:16864869 PMID:17020896 PMID:17179007 PMID:17610934 PMID:17948137 PMID:18179203 PMID:18182702 PMID:18306736 PMID:18443210 PMID:18592736 PMID:19107210 PMID:19229032 PMID:19297450 PMID:19509065 PMID:26352695 PMID:26365231 PMID:7548021 PMID:7581816 PMID:8048546 PMID:8375042 PMID:8451754 PMID:9051670 PMID:9100841 PMID:9168257 PMID:9202721 PMID:9558114 PPDB:387 Reaxys:3587191 Wikipedia:Hydrogen_peroxide HYDROGEN PEROXIDE Hydrogen peroxide bis(hydridooxygen)(O--O) dihydrogen peroxide dihydrogen(peroxide) dioxidane hydrogen peroxide chebi_ontology H2O2 HOOH Oxydol [OH(OH)] dihydrogen dioxide perhydrol CHEBI:16240 hydrogen peroxide A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides. CHEBI:14816 CHEBI:26063 CHEBI:8150 KEGG:C00865 Phospholipid chebi_ontology a phospholipid derivative phospholipids CHEBI:16247 phospholipid A derivative of glycerol in which one hydroxy group, commonly but not necessarily primary, is esterified with phosphoric acid and the other two are esterified with fatty acids. 0 C5H7O8PR2 226.07800 225.98785 OP(O)(=O)OCC(COC([*])=O)OC([*])=O CHEBI:14795 CHEBI:26023 CHEBI:8122 KEGG:C00416 Phosphatidic acid chebi_ontology 1,2-Diacyl-sn-glycerol 3-phosphate 3-sn-Phosphatidate Phosphatidate phosphatidic acids CHEBI:16337 phosphatidic acid Any benzoquinone derived from 2,3-dimethoxy-5-methylbenzoquinone; one of a group of naturally occurring homologues. The redox-active quinoid moiety usually carries a polyprenoid side chain at position 6, the number of isoprenoid units in which is species-specific. Ubiquinones are involved in the control of mitochondrial electron transport, and are also potent anti-oxidants. 0 C9H10O4(C5H8)n CHEBI:15279 CHEBI:27186 CHEBI:9852 CAS:1339-63-5 KEGG:C00399 PMID:15788391 PMID:7599208 Ubiquinones chebi_ontology CoQ Coenzym Q Coenzyme Q Koenzym Q Q Ubichinon Ubiquinone a ubiquinone coenzyme Q coenzymes Q mitochondrial ubiquinone mitochondrial ubiquinones mitoquinones CHEBI:16389 ubiquinones A sphing-4-enine in which the double bond is trans. 0 C18H37NO2 InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1 WWUZIQQURGPMPG-KRWOKUGFSA-N 299.49190 299.28243 CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO CHEBI:15102 CHEBI:207585 CHEBI:26741 CHEBI:9224 Beilstein:1727294 Beilstein:4676153 CAS:123-78-4 DrugBank:DB03203 HMDB:HMDB0000252 KEGG:C00319 LIPID_MAPS_instance:LMSP01010001 PDBeChem:SQS PMID:10453988 PMID:16341241 PMID:24731183 PMID:8482346 Reaxys:1727294 (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol Sphingosine chebi_ontology (2S,3R)-(E)-2-amino-1,3-dihydroxy-4-octadecene (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-ene-1-ol (2S,3R,4E)-2-amino-4-octadecene-1,3-diol (2S,3R,E)-2-aminooctadec-4-ene-1,3-diol (4E)-sphing-4-enine (4E)-sphingenine (E)-2-amino-4-octadecan-1,3-diol (E)-D-erythro-4-octadecene-1,3-diol 2-amino-4-octadecene-1,3-diol C18 sphingosine D-(+)-erythro-1,3-dihydroxy-2-amino-4-trans-octadecene D-erythro-sphingosine Sph Sphing-4-enine Sphingenine Sphingoid Sphingosine d18:1 sphingosin trans-4-sphingenine trans-D-erythro-2-amino-4-octadecene-1,3-diol CHEBI:16393 sphingosine The reduced form of NADP+; used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. 0 C21H30N7O17P3 InChI=1S/C21H30N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 ACFIXJIJDZMPPO-NNYOXOHSSA-N 745.42116 745.09110 NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O CHEBI:13399 CHEBI:13400 CHEBI:21904 CHEBI:44286 CHEBI:7425 Beilstein:77911 CAS:53-57-6 COMe:MOL000028 ECMDB:ECMDB04111 HMDB:HMDB0000221 KEGG:C00005 KNApSAcK:C00019545 PDBeChem:NDP PMID:16884311 PMID:17371809 PMID:8627598 YMDB:YMDB00426 2'-O-phosphonoadenosine 5'-{3-[1-(3-carbamoyl-1,4-dihydropyridin-1-yl)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate} NADPH chebi_ontology NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Reduced nicotinamide adenine dinucleotide phosphate TPNH dihydronicotinamide-adenine dinucleotide phosphate reduced nicotinamide-adenine dinucleotide phosphate CHEBI:16474 NADPH A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position. 0 C8H14O2S2 InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) AGBQKNBQESQNJD-UHFFFAOYSA-N 206.32756 206.04352 OC(=O)CCCCC1CCSS1 CHEBI:146958 CHEBI:25058 CHEBI:6492 Beilstein:122410 Beilstein:81853 CAS:62-46-4 DrugBank:DB00166 Drug_Central:4732 ECMDB:ECMDB01451 Gmelin:720915 KEGG:C00725 KEGG:D00086 PMID:7519986 PMID:7548757 Reaxys:81853 Wikipedia:Lipoic_acid YMDB:YMDB00334 5-(1,2-dithiolan-3-yl)pentanoic acid Lipoic acid chebi_ontology 1,2-dithiolane-3-pentanoic acid 1,2-dithiolane-3-valeric acid 5-(1,2-dithiolan-3-yl)valeric acid 5-(dithiolan-3-yl)valeric acid 5-[3-(1,2-dithiolanyl)]pentanoic acid 6,8-thioctic acid 6,8-thiotic acid 6-thioctic acid 6-thiotic acid Acetate-replacing factor Biletan Thioctansaeure Thioctic acid Thioctsaeure Thioktsaeure alpha-Lipoic acid alpha-Liponsaeure alpha-lipoic acid liponic acid CHEBI:16494 lipoic acid A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived. 0 C30H50O InChI=1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1 CAHGCLMLTWQZNJ-BQNIITSRSA-N 426.71740 426.38617 C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3 CHEBI:14500 CHEBI:25011 CHEBI:43584 CHEBI:6374 Beilstein:2226449 CAS:79-63-0 DrugBank:DB03696 HMDB:HMDB0001251 KEGG:C01724 KNApSAcK:C00003657 LIPID_MAPS_instance:LMST01010017 MetaCyc:LANOSTEROL PDBeChem:LAN PMID:14660793 PMID:16445886 PMID:21818119 PMID:21838962 PMID:22824432 PMID:22933236 PMID:22988818 PMID:24525128 PMID:26069216 PMID:26200341 Reaxys:2226449 Wikipedia:Lanosterol LANOSTEROL Lanosterol lanosta-8,24-dien-3beta-ol lanosterol chebi_ontology (3beta)-lanosta-8,24-dien-3-ol (3beta,5alpha)-4,4,14-trimethylcholesta-8,24-dien-3-ol 4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol Lanosterin CHEBI:16521 lanosterol A naturally occurring polypeptide synthesized at the ribosome. CHEBI:8526 KEGG:C00017 chebi_ontology Protein polypeptide chain protein polypeptide chains CHEBI:16541 protein polypeptide chain A prenol phosphate comprising 3-methylbut-3-en-1-ol having an O-diphosphate substituent. 0 C5H12O7P2 InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h1,3-4H2,2H3,(H,9,10)(H2,6,7,8) NUHSROFQTUXZQQ-UHFFFAOYSA-N 246.09210 246.00583 CC(=C)CCOP(O)(=O)OP(O)(O)=O CHEBI:14473 CHEBI:24907 CHEBI:6037 Beilstein:1713792 CAS:358-71-4 DrugBank:DB04714 KEGG:C00129 KNApSAcK:C00000848 LIPID_MAPS_instance:LMPR01010008 PDBeChem:IPE PMID:11278429 PMID:15450402 PMID:23000003 PMID:23543734 PMID:23747531 PMID:23872678 PMID:7584140 PMID:7753173 Reaxys:1713792 Wikipedia:Isopentenyl_pyrophosphate 3-methylbut-3-en-1-yl trihydrogen diphosphate Isopentenyl diphosphate chebi_ontology 3-Methyl-3-butenyl pyrophosphate 3-methylbut-3-en-1-yl trihydrogen diphosphate 3-methylbut-3-enyl phosphono hydrogen phosphate Diphosphoric acid mono(3-methyl-3-butenyl) ester IPP IPPP Isopentenyl pyrophosphate Mono(3-methyl-3-butenyl) diphosphate delta-3-Isopentenyl pyrophosphate delta3-Isopentenyl diphosphate delta3-Methyl-3-butenyl diphosphate delta3-isopentenyl diphosphate CHEBI:16584 isopentenyl diphosphate An aminosulfinic acid comprising ethylamine having the sulfo group at the 2-position. 0 C2H7NO2S InChI=1S/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5) VVIUBCNYACGLLV-UHFFFAOYSA-N 109.14852 109.01975 NCCS(O)=O CHEBI:14429 CHEBI:24760 CHEBI:5839 CAS:300-84-5 HMDB:HMDB0000965 KEGG:C00519 MetaCyc:HYPOTAURINE PMID:22735334 Reaxys:1743127 Wikipedia:Hypotaurine 2-aminoethanesulfinic acid Hypotaurine chebi_ontology 2-Aminoethanesulfinic acid CHEBI:16668 hypotaurine Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc. 0 (C2H2NOR)nC2H3NOR CHEBI:14753 CHEBI:25906 CHEBI:7990 KEGG:C00012 Peptide peptides chebi_ontology Peptid peptido peptidos CHEBI:16670 peptide A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans. 0 C13H16N2O2 InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16) DRLFMBDRBRZALE-UHFFFAOYSA-N 232.283 232.12118 C=1C=C(C=C2C(=CNC12)CCNC(=O)C)OC CHEBI:14577 CHEBI:25180 CHEBI:6730 Beilstein:205542 CAS:73-31-4 DrugBank:DB01065 Drug_Central:1672 HMDB:HMDB0001389 KEGG:C01598 KEGG:D08170 LINCS:LSM-4779 MetaCyc:N-ACETYL-5-METHOXY-TRYPTAMINE PDBeChem:ML1 PMID:16678784 PMID:18212404 PMID:18485664 Reaxys:205542 Wikipedia:Melatonin Melatonin N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide melatonin chebi_ontology 5-methoxy-N-acetyltryptamine N-Acetyl-5-methoxytryptamine N-[2-(5-methoxyindol-3-yl)ethyl]acetamide melatonine CHEBI:16796 melatonin A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. 0 C5H11NO2S InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8) FFEARJCKVFRZRR-UHFFFAOYSA-N 149.21238 149.05105 CSCCC(N)C(O)=O CHEBI:14590 CHEBI:25229 CHEBI:6829 Beilstein:636185 CAS:59-51-8 Gmelin:3117 KEGG:C01733 KEGG:D04983 PMID:16702333 PMID:22264337 PMID:2543976 Reaxys:636185 UM-BBD_compID:c0094 Wikipedia:Methionine Methionine methionine chebi_ontology 2-Amino-4-(methylthio)butyric acid 2-amino-4-(methylsulfanyl)butanoic acid 2-amino-4-(methylthio)butanoic acid DL-Methionine Hmet M Met Methionin Racemethionine alpha-amino-gamma-methylmercaptobutyric acid metionina CHEBI:16811 methionine The L-enantiomer of tryptophan. 0 C11H12N2O2 InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1 QIVBCDIJIAJPQS-VIFPVBQESA-N 204.22526 204.08988 N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O CHEBI:13178 CHEBI:184633 CHEBI:21407 CHEBI:45988 CHEBI:46086 CHEBI:46125 CHEBI:46225 CHEBI:6310 Beilstein:86197 CAS:73-22-3 DrugBank:DB00150 Drug_Central:2780 ECMDB:ECMDB00929 Gmelin:51434 HMDB:HMDB0000929 KEGG:C00078 KEGG:D00020 KNApSAcK:C00001396 MetaCyc:TRP PDBeChem:TRP PMID:11395471 PMID:11750787 PMID:11888576 PMID:12766158 PMID:12830226 PMID:12871129 PMID:15206750 PMID:16740930 PMID:16934873 PMID:17127472 PMID:17177562 PMID:17430113 PMID:17585690 PMID:17690425 PMID:17826001 PMID:18234569 PMID:18419734 PMID:18949702 PMID:19896323 PMID:21856896 PMID:22071091 PMID:22162421 PMID:22299628 PMID:22386992 PMID:22402312 PMID:22415302 PMID:22415306 PMID:2917974 Reaxys:86197 Wikipedia:Tryptophan YMDB:YMDB00126 L-Tryptophan L-tryptophan chebi_ontology (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid (S)-alpha-Amino-beta-(3-indolyl)-propionic acid (S)-alpha-amino-1H-indole-3-propanoic acid (S)-tryptophan L-(-)-tryptophan L-beta-3-indolylalanine TRYPTOPHAN Trp Tryptophan W tryptophan CHEBI:16828 L-tryptophan A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine. 0 C10H17N3O6S InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1 RWSXRVCMGQZWBV-WDSKDSINSA-N 307.320 307.08381 N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O CHEBI:12402 CHEBI:14327 CHEBI:24334 CHEBI:42873 CHEBI:43049 CHEBI:5437 CAS:70-18-8 DrugBank:DB00143 Drug_Central:1312 HMDB:HMDB0000125 KEGG:C00051 KEGG:D00014 KNApSAcK:C00001518 MetaCyc:GLUTATHIONE PDBeChem:GSH PMID:17439666 PMID:4200890 PMID:4745654 Reaxys:1729812 Wikipedia:Glutathione Glutathione L-gamma-glutamyl-L-cysteinylglycine chebi_ontology 5-L-Glutamyl-L-cysteinylglycine GSH Glutathione-SH N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine Reduced glutathione gamma-L-Glutamyl-L-cysteinyl-glycine CHEBI:16856 glutathione A gamma-amino acid that is butanoic acid with the amino substituent located at C-4. 0 C4H9NO2 InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) BTCSSZJGUNDROE-UHFFFAOYSA-N 103.11980 103.06333 NCCCC(O)=O CHEBI:1786 CHEBI:193777 CHEBI:20318 CHEBI:40483 BPDB:2298 Beilstein:906818 CAS:56-12-2 DrugBank:DB02530 Drug_Central:1262 Gmelin:49775 HMDB:HMDB0000112 KEGG:C00334 KEGG:D00058 KNApSAcK:C00001337 LIPID_MAPS_instance:LMFA01100039 MetaCyc:4-AMINO-BUTYRATE PDBeChem:ABU PMID:10630630 PMID:10930630 PMID:16276116 PMID:21614609 PMID:22770225 Reaxys:906818 Wikipedia:Gamma-Aminobutyric_acid 4-aminobutanoic acid gamma-Aminobutyric acid gamma-aminobutyric acid chebi_ontology 4-Aminobutanoic acid 4-Aminobutyric acid 4-aminobutanoic acid 4-aminobutyric acid 4Abu GABA GAMMA-AMINO-BUTANOIC ACID gamma-Aminobuttersaeure gamma-amino-n-butyric acid gamma-aminobutanoic acid omega-aminobutyric acid piperidic acid piperidinic acid CHEBI:16865 gamma-aminobutyric acid A coenzyme found in all living cells; consists of two nucleotides joined through their 5'-phosphate groups, with one nucleotide containing an adenine base and the other containing nicotinamide. 0 C21H29N7O14P2 InChI=1S/C21H29N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 BOPGDPNILDQYTO-NNYOXOHSSA-N 665.44126 665.12477 NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O CHEBI:13395 CHEBI:13396 CHEBI:21902 CHEBI:44216 CHEBI:7423 Beilstein:79324 CAS:58-68-4 COMe:MOL000027 DrugBank:DB00157 Gmelin:544241 HMDB:HMDB0001487 KEGG:C00004 KNApSAcK:C00019343 PDBeChem:NAI PMID:11259315 PMID:19459318 Reaxys:79324 Wikipedia:Nicotinamide_adenine_dinucleotide NADH adenosine 5'-{3-[1-(3-carbamoyl-1,4-dihydropyridin-1-yl)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate} chebi_ontology 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE DPNH Reduced nicotinamide adenine dinucleotide nicotinamide adenine dinucleotide (reduced) CHEBI:16908 NADH High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms. CHEBI:13302 CHEBI:21123 CHEBI:33698 CHEBI:4291 CAS:9007-49-2 KEGG:C00039 Deoxyribonucleic acid deoxyribonucleic acids chebi_ontology (Deoxyribonucleotide)m (Deoxyribonucleotide)n (Deoxyribonucleotide)n+m DNA DNAn DNAn+1 DNS Desoxyribonukleinsaeure deoxyribonucleic acids desoxyribose nucleic acid thymus nucleic acid CHEBI:16991 deoxyribonucleic acid A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H). 0 COR2 28.010 27.99491 [*]C([*])=O CHEBI:13427 CHEBI:13646 CHEBI:24974 CHEBI:6127 CHEBI:8742 KEGG:C01450 Wikipedia:Ketone Ketone ketones chebi_ontology Keton R-CO-R' a ketone cetone ketones CHEBI:17087 ketone The diphosphate of the polyprenol compound geraniol. 0 C10H20O7P2 InChI=1S/C10H20O7P2/c1-9(2)5-4-6-10(3)7-8-16-19(14,15)17-18(11,12)13/h5,7H,4,6,8H2,1-3H3,(H,14,15)(H2,11,12,13)/b10-7+ GVVPGTZRZFNKDS-JXMROGBWSA-N 314.20912 314.06843 CC(C)=CCC\C(C)=C\COP(O)(=O)OP(O)(O)=O CHEBI:14299 CHEBI:24223 CHEBI:42877 CHEBI:5332 Beilstein:1915690 CAS:763-10-0 DrugBank:DB02552 KEGG:C00341 KNApSAcK:C00000846 LIPID_MAPS_instance:LMPR0102010001 PDBeChem:GPP PMID:19049370 PMID:19856009 PMID:23607888 PMID:7753173 Reaxys:1915690 (2E)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate GERANYL DIPHOSPHATE Geranyl diphosphate chebi_ontology geranyl pyrophosphate CHEBI:17211 geranyl diphosphate A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain. 0 C4H9NO2S InChI=1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7) FFFHZYDWPBMWHY-UHFFFAOYSA-N 135.18580 135.03540 NC(CCS)C(O)=O CHEBI:14408 CHEBI:5751 HMDB:HMDB0000742 KEGG:C05330 PMID:11133260 PMID:16596805 PMID:18370634 Wikipedia:Homocysteine 2-amino-4-sulfanylbutanoic acid Homocysteine homocysteine chebi_ontology 2-Amino-4-mercaptobutyric acid Hcy CHEBI:17230 homocysteine An aldohexose used as a source of energy and metabolic intermediate. 0 C6H12O6 180.15588 180.06339 CHEBI:14313 CHEBI:24277 CHEBI:33929 CHEBI:5418 CAS:50-99-7 KEGG:C00293 Wikipedia:Glucose Glucose gluco-hexose glucose chebi_ontology DL-glucose Glc Glukose CHEBI:17234 glucose An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.. 0 C19H28O2 InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 288.42440 288.20893 [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H] CHEBI:15214 CHEBI:26883 CHEBI:45798 CHEBI:9461 Beilstein:1915399 Beilstein:3653705 CAS:58-22-0 DrugBank:DB00624 Drug_Central:2607 Gmelin:538843 HMDB:HMDB0000234 KEGG:C00535 KEGG:D00075 KNApSAcK:C00003675 LIPID_MAPS_instance:LMST02020002 PDBeChem:TES PMID:10438974 PMID:11786693 PMID:18900503 PMID:24498482 Reaxys:1915399 Wikipedia:Testosterone 17beta-hydroxyandrost-4-en-3-one TESTOSTERONE Testosterone testosterone chebi_ontology 17beta-Hydroxy-4-androsten-3-one 17beta-hydroxy-4-androsten-3-one 4-androsten-17beta-ol-3-one Androderm Testosteron testosterona testosterone testosteronum CHEBI:17347 testosterone A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3). -2 O3S InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2 LSNNMFCWUKXFEE-UHFFFAOYSA-L 80.06420 79.95791 [O-]S([O-])=O CHEBI:15139 CHEBI:45548 CAS:14265-45-3 Gmelin:1449 PDBeChem:SO3 sulfite trioxidosulfate(2-) trioxosulfate(2-) trioxosulfate(IV) chebi_ontology SO3 SO3(2-) SULFITE ION [SO3](2-) sulphite CHEBI:17359 sulfite A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group. 0 CHOR 29.01800 29.00274 [H]C([*])=O CHEBI:13432 CHEBI:13753 CHEBI:13805 CHEBI:13806 CHEBI:22291 CHEBI:2554 CHEBI:8750 KEGG:C00071 Aldehyde aldehyde aldehydes chebi_ontology Aldehyd RC(=O)H RCHO aldehido aldehidos aldehydes aldehydum an aldehyde CHEBI:17478 aldehyde Any B-vitamin that exhibits biological activity against vitamin B9 deficiency. Vitamin B9 refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B9 leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B9 deficiency include fatigue, muscle weakness, and pale skin. vitamin B9 chebi_ontology folate vitamer folate vitamers vitamin B-9 vitamin B9 vitamer vitamin B9 vitamers vitamins B9 CHEBI:176842 vitamin B9 Any member of a group of cobalamin vitamers that exhibit biological activity against vitamin B12 deficiency. Vitamin B12 deficiency is associated with low red blood cell count and anemia. The vitamers are found in foods such as cereals, meat, fish, and poultry. The vitamers include adenosylcobalamin, hydroxocobalamin, cyanocobalamin, aquacobalamin, nitritocobalamin and methylcobabalamin (also includes their ionized, salt and phosphate derivatives). vitamin B12 chebi_ontology vitamin B-12 vitamin B12 vitamer vitamin B12 vitamers vitamins B12 CHEBI:176843 vitamin B12 Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R(1) = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H. 0 C4H6NO2R3 100.09590 100.03985 O[C@H]([*])[C@H](C[*])NC([*])=O CHEBI:12487 CHEBI:13954 CHEBI:23074 CHEBI:7242 KEGG:C00195 LIPID_MAPS_class:LMSP02 PMID:7542630 Wikipedia:Ceramide Ceramide chebi_ontology Cer N-acylated sphingoid a ceramide ceramides CHEBI:17761 ceramide A compound containing at least one carbon-halogen bond (where X is a halogen atom). 0 RX ** CHEBI:13444 CHEBI:36684 CHEBI:8767 KEGG:C01322 MetaCyc:Organohalogen-Compounds chebi_ontology RX organic halide organic halides organohalogen compounds CHEBI:17792 organohalogen compound 0 C20H32N6O12S2 InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1 YPZRWBKMTBYPTK-BJDJZHNGSA-N 612.63332 612.15196 N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O CHEBI:14328 CHEBI:14720 CHEBI:24336 CHEBI:42832 CHEBI:7840 CAS:27025-41-8 DrugBank:DB03310 Drug_Central:5130 KEGG:C00127 KEGG:D00031 PDBeChem:GDS (2S,2'S)-5,5'-[disulfanediylbis({(2R)-3-[(carboxymethyl)amino]-3-oxopropane-1,2-diyl}imino)]bis(2-amino-5-oxopentanoic acid) Glutathione disulfide chebi_ontology GSSG OXIDIZED GLUTATHIONE DISULFIDE Oxidized glutathione Oxiglutatione glutathione disulphide oxidised glutathione CHEBI:17858 glutathione disulfide 0 C9H12O4(C5H8)n CHEBI:15278 CHEBI:27182 CHEBI:9851 CAS:56275-39-9 KEGG:C00390 Ubiquinol chebi_ontology CoQH2 QH(2) QH2 a ubiquinol coenzymes QH2 reduced ubiquinone ubiquinols CHEBI:17976 ubiquinol A thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid. 0 C22H35N7O17P3SR 794.53600 794.10230 CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC([*])=O CHEBI:13727 CHEBI:13802 CHEBI:22223 CHEBI:2455 CAS:9029-97-4 KEGG:C00040 PMID:11264983 PMID:11524729 PMID:16495773 PMID:21514367 PMID:21541677 Acyl-CoA chebi_ontology Acyl coenzyme A CHEBI:17984 acyl-CoA A halide anion formed when chlorine picks up an electron to form an an anion. -1 Cl InChI=1S/ClH/h1H/p-1 VEXZGXHMUGYJMC-UHFFFAOYSA-M 35.45270 34.96940 [Cl-] CHEBI:13291 CHEBI:13970 CHEBI:3616 CHEBI:3731 CHEBI:48804 Beilstein:3587171 CAS:16887-00-6 Gmelin:14910 KEGG:C00115 KEGG:C00698 PDBeChem:CL UM-BBD_compID:c0884 Chloride chloride chloride(1-) chebi_ontology CHLORIDE ION Chloride ion Chloride(1-) Chlorine anion Cl(-) Cl- CHEBI:17996 chloride +1 C21H29N7O17P3 InChI=1S/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 XJLXINKUBYWONI-NNYOXOHSSA-O 744.41322 744.08273 NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O CHEBI:13398 CHEBI:21903 CHEBI:7424 Beilstein:3645734 CAS:53-59-8 COMe:MOL000029 KEGG:C00006 PDBeChem:NAP 2'-O-phosphonoadenosine 5'-{3-[1-(3-carbamoylpyridinio)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate} chebi_ontology NADP NADP+ Nicotinamide adenine dinucleotide phosphate TPN Triphosphopyridine nucleotide beta-Nicotinamide adenine dinucleotide phosphate beta-nicotinamide adenine dinucleotide phosphate oxidized nicotinamide-adenine dinucleotide phosphate CHEBI:18009 NADP(+) A pseudohalide anion obtained by deprotonation of the thiol group of thiocyanic acid. -1 CNS InChI=1S/CHNS/c2-1-3/h3H/p-1 ZMZDMBWJUHKJPS-UHFFFAOYSA-M 58.08344 57.97569 [S-]C#N CHEBI:15234 CHEBI:24926 CHEBI:26954 CHEBI:45576 Beilstein:1901207 CAS:302-04-5 Gmelin:1089 PDBeChem:SCN UM-BBD_compID:c0560 nitridosulfidocarbonate(1-) nitridothiocarbonate(1-) nitridothiocarbonate(IV) thiocyanate chebi_ontology N#C-S(-) NCS- Rhodanid SCN(-) THIOCYANATE ION Thiozyanat [S-C#N](-) rhodanide thiocyanate ion (1-) CHEBI:18022 thiocyanate 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids. CHEBI:14517 CHEBI:25054 CHEBI:6486 KEGG:C01356 Lipid lipids chebi_ontology CHEBI:18059 lipid The parent compound of the citrulline class consisting of ornithine having a carbamoyl group at the N(5)-position. 0 C6H13N3O3 InChI=1S/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12) RHGKLRLOHDJJDR-UHFFFAOYSA-N 175.18584 175.09569 NC(CCCNC(N)=O)C(O)=O CHEBI:14002 CHEBI:3730 Beilstein:1725417 Beilstein:2328251 CAS:627-77-0 PMID:11094453 PMID:11113071 PMID:11696417 PMID:1378088 PMID:16082501 PMID:16708633 PMID:17005970 PMID:17513438 PMID:17558653 PMID:17693747 PMID:18437289 PMID:18440672 PMID:18989563 PMID:19144577 PMID:21129371 PMID:21482070 Reaxys:1725417 Wikipedia:Citrulline 2-amino-5-(carbamoylamino)pentanoic acid Citrulline N(5)-carbamoylornithine citrulline chebi_ontology 2-Amino-5-uredovaleric acid Cit Citrullin DL-2-amino-5-ureidovaleric acid N(5)-(aminocarbonyl)-DL-ornithine N(5)-(aminocarbonyl)ornithine N(5)-carbamoyl-DL-ornithine citrulina dl-citrulline CHEBI:18211 citrulline Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group. 0 C8H11NO2 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 153.17840 153.07898 NCCc1ccc(O)c(O)c1 CHEBI:11695 CHEBI:11930 CHEBI:14203 CHEBI:1764 CHEBI:23886 CHEBI:43686 CAS:51-61-6 DrugBank:DB00988 Drug_Central:947 HMDB:HMDB0000073 KEGG:C03758 KEGG:D07870 KNApSAcK:C00001408 LINCS:LSM-4630 MetaCyc:DOPAMINE PMID:10629745 PMID:11149432 PMID:9422813 Reaxys:1072822 Wikipedia:Dopamine 4-(2-aminoethyl)benzene-1,2-diol Dopamine chebi_ontology 2-(3,4-Dihydroxyphenyl)ethylamine 2-(3,4-dihydroxyphenyl)ethylamine 3,4-Dihydroxyphenethylamine 3-Hydroxytyramine 4-(2-Aminoethyl)-1,2-benzenediol 4-(2-Aminoethyl)benzene-1,2-diol 4-(2-aminoethyl)-1,2-benzenediol 4-(2-aminoethyl)catechol 4-(2-aminoethyl)pyrocatechol Deoxyepinephrine Hydroxytyramin dopamina dopamine dopaminum CHEBI:18243 dopamine An iron group element atom that has atomic number 26. 0 Fe InChI=1S/Fe XEEYBQQBJWHFJM-UHFFFAOYSA-N 55.84500 55.93494 [Fe] CHEBI:13322 CHEBI:24872 CHEBI:5974 CAS:7439-89-6 DrugBank:DB01592 HMDB:HMDB0015531 KEGG:C00023 Reaxys:4122945 WebElements:Fe iron chebi_ontology 26Fe Eisen Fe Iron fer ferrum hierro iron CHEBI:18248 iron atom A compound having the structure RC#N; thus a C-substituted derivative of hydrocyanic acid, HC#N. In systematic nomenclature, the suffix nitrile denotes the triply bound #N atom, not the carbon atom attached to it. 0 CNR 26.01740 26.00307 [*]C#N CHEBI:13212 CHEBI:13426 CHEBI:13660 CHEBI:25547 CHEBI:7584 KEGG:C00726 Nitrile nitrile nitriles chebi_ontology Nitril R-CN a nitrile nitrilos CHEBI:18379 nitrile +2 Mg InChI=1S/Mg/q+2 JLVVSXFLKOJNIY-UHFFFAOYSA-N 24.30500 23.98394 [Mg++] CHEBI:13379 CHEBI:25112 CHEBI:49736 CHEBI:6635 CAS:22537-22-0 Gmelin:6857 KEGG:C00305 PDBeChem:MG magnesium cation magnesium(2+) magnesium(2+) ion magnesium(II) cation chebi_ontology MAGNESIUM ION Mg(2+) Mg2+ magnesium, doubly charged positive ion magnesium, ion (Mg(2+)) CHEBI:18420 magnesium(2+) -1 O2 InChI=1S/HO2/c1-2/h1H/p-1 OUUQCZGPVNCOIJ-UHFFFAOYSA-M 31.99880 31.98983 [O][O-] CHEBI:15143 CHEBI:26839 CHEBI:7710 CAS:11062-77-4 Gmelin:487 KEGG:C00704 dioxidanidyl dioxide(.1-) superoxide chebi_ontology (O2)(.-) Hyperoxid O2(-) O2(.-) O2- O2.- Superoxide anion dioxide(1-) hyperoxide superoxide anion radical superoxide radical superoxide radical anion superoxyde CHEBI:18421 superoxide A hydroxy fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any 3-hydroxy fatty acid. 0 C24H39N7O18P3SR 838.58900 838.12851 CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)[*] PMID:12106015 PMID:1778900 PMID:20583174 PMID:20670938 PMID:20923481 PMID:21502722 PMID:7552767 chebi_ontology 3-hydroxy fatty acyl CoA 3-hydroxy fatty acyl CoAs 3-hydroxy fatty acyl coenzyme A 3-hydroxy fatty acyl coenzyme As 3-hydroxyacyl-CoAs beta-hydroxy fatty acyl-CoA beta-hydroxy fatty acyl-CoAs beta-hydroxy fatty acyl-coenzyme A beta-hydroxy fatty acyl-coenzyme As beta-hydroxyacyl-CoA beta-hydroxyacyl-CoAs beta-hydroxyacyl-coenzyme A beta-hydroxyacyl-coenzyme As CHEBI:20060 3-hydroxy fatty acyl-CoA A N-acyl-D-glucosamine 1-phosphate in which the acyl group specified is acetyl. chebi_ontology CHEBI:21519 N-acetyl-D-glucosamine 1-phosphate chebi_ontology CHEBI:22198 acetylcysteine chebi_ontology adenosine bisphosphates CHEBI:22251 adenosine bisphosphate chebi_ontology adenosine phosphates CHEBI:22256 adenosine phosphate A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. chebi_ontology antioxidants antioxydant antoxidant CHEBI:22586 antioxidant Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group. chebi_ontology CHEBI:22723 benzoic acids MetaCyc:All-Biopterines chebi_ontology CHEBI:22881 biopterins Benzenoid aromatic compounds containing two phenyl or substituted-phenyl groups which are joined together by a single bond. chebi_ontology CHEBI:22888 biphenyls 0 Ca InChI=1S/Ca OYPRJOBELJOOCE-UHFFFAOYSA-N 40.07800 39.96259 [Ca] CAS:7440-70-2 DrugBank:DB01373 KEGG:C00076 WebElements:Ca calcium chebi_ontology 20Ca Ca Calcium Kalzium calcio calcium CHEBI:22984 calcium atom 0 CO 28.01010 27.99491 O=C(*)* carbonyl carbonyl group chebi_ontology >C=O CHEBI:23019 carbonyl group Members of the class of hydroxyflavan that have a flavan-3-ol skeleton and its substituted derivatives. 0 C15H14O6 InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2 PFTAWBLQPZVEMU-UHFFFAOYSA-N 290.269 290.07904 C1(C=2C=C(C(O)=CC2)O)OC=3C(=C(C=C(C3)O)O)CC1O KEGG:C17590 LINCS:LSM-1682 catechin chebi_ontology (+/-)-Catechin catechins CHEBI:23053 catechin Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. molecular entity chebi_ontology entidad molecular entidades moleculares entite moleculaire molecular entities molekulare Entitaet CHEBI:23367 molecular entity A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols. Wikipedia:Diol diols chebi_ontology CHEBI:23824 diol Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. chebi_ontology drugs medicine CHEBI:23888 drug A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. enzyme inhibitor chebi_ontology enzyme inhibitors inhibidor enzimatico inhibidores enzimaticos inhibiteur enzymatique inhibiteurs enzymatiques CHEBI:23924 enzyme inhibitor chebi_ontology ethanolamine CHEBI:23981 ethanolamines A member of the class of phenothiazines that is 10H-phenothiazine substituted by a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the nitogen atom and an acetyl group at position 2. 0 C23H29N3O2S InChI=1S/C23H29N3O2S/c1-18(28)19-7-8-23-21(17-19)26(20-5-2-3-6-22(20)29-23)10-4-9-24-11-13-25(14-12-24)15-16-27/h2-3,5-8,17,27H,4,9-16H2,1H3 WNTYBHLDCKXEOT-UHFFFAOYSA-N 411.56138 411.19805 CC(=O)c1ccc2Sc3ccccc3N(CCCN3CCN(CCO)CC3)c2c1 Beilstein:57631 CAS:2751-68-0 DrugBank:DB01063 Drug_Central:59 HMDB:HMDB0015196 KEGG:C06807 PMID:13904111 PMID:13986480 PMID:14020672 PMID:14211419 Reaxys:57631 Wikipedia:Acetophenazine 1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)ethanone Acetophenazine chebi_ontology CHEBI:2401 acetophenazine fluorine molecular entity chebi_ontology fluorine compounds fluorine molecular entities CHEBI:24062 fluorine molecular entity Compounds containing at least one furan ring. chebi_ontology oxacyclopenta-2,4-dienes CHEBI:24129 furans Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood. chebi_ontology glucocorticoids CHEBI:24261 glucocorticoid A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. chemical entity chebi_ontology CHEBI:24431 chemical entity A role played by the molecular entity or part thereof within a biological context. chebi_ontology biological function CHEBI:24432 biological role A defined linked collection of atoms or a single atom within a molecular entity. group chebi_ontology Gruppe Rest groupe grupo grupos CHEBI:24433 group halogen molecular entity chebi_ontology halogen compounds halogen molecular entities CHEBI:24471 halogen molecular entity A cyclic compound having as ring members atoms of carbon and at least of one other element. chebi_ontology organic heterocycle organic heterocyclic compounds CHEBI:24532 organic heterocyclic compound Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. chebi_ontology endocrine hormones CHEBI:24621 hormone Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)). chebi_ontology CHEBI:24651 hydroxides Any carboxylic acid with at least one hydroxy group. chebi_ontology hydroxy carboxylic acids hydroxycarboxylic acid hydroxycarboxylic acids CHEBI:24669 hydroxy carboxylic acid A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). oxoacid oxoacids chebi_ontology oxacids oxiacids oxo acid oxy-acids oxyacids CHEBI:24833 oxoacid A molecular entity having a net electric charge. Ion ion chebi_ontology Ionen iones ions CHEBI:24870 ion Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives. LIPID_MAPS_class:LMPR01 PMID:12769708 PMID:19219049 isoprenoid isoprenoids chebi_ontology isoprenoids CHEBI:24913 isoprenoid Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. lactone lactones chebi_ontology Lacton Lakton Laktone lactona lactonas CHEBI:25000 lactone 0 Pb InChI=1S/Pb WABPQHHGFIMREM-UHFFFAOYSA-N 207.20000 207.97665 [Pb] KEGG:C06696 WebElements:Pb lead chebi_ontology 82Pb Blei Pb lead plomb plomo plumbum CHEBI:25016 lead atom Any icosanoid from that family of C20 polyunsaturated fatty acids and their derivatives generated by leukocytes from arachidonic acid, each member having four double bonds of which three are conjugated. LIPID_MAPS_class:LMFA0302 PMID:10922142 PMID:15794321 PMID:3001504 PMID:6129158 PMID:6293196 PMID:6311078 PMID:8842590 PMID:9526099 PMID:9561094 Leukotriene leukotriene leukotrienes chebi_ontology Leukotrien leucotriene leucotrienes leukotrienes CHEBI:25029 leukotriene A dihydroxy monocarboxylic acid comprising valeric acid having two hydroxy groups at the 3- and 5-positions together with a methyl group at the 3-position. 0 C6H12O4 InChI=1S/C6H12O4/c1-6(10,2-3-7)4-5(8)9/h7,10H,2-4H2,1H3,(H,8,9) KJTLQQUUPVSXIM-UHFFFAOYSA-N 148.15708 148.07356 CC(O)(CCO)CC(O)=O Beilstein:1722595 HMDB:HMDB0000227 PMID:22770225 Reaxys:1722595 3,5-dihydroxy-3-methylpentanoic acid chebi_ontology DL-Mevalonic acid MVA RS-Mevalonic acid CHEBI:25351 mevalonic acid Any polyatomic entity that is an electrically neutral entity consisting of more than one atom. molecule chebi_ontology Molekuel molecula molecules neutral molecular compounds CHEBI:25367 molecule An oxoacid containing a single carboxy group. chebi_ontology monocarboxylic acids CHEBI:25384 monocarboxylic acid A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates. KEGG:C01329 chebi_ontology NMP Nucleoside monophosphate nucleoside phosphates CHEBI:25608 nucleoside phosphate A family of polyunsaturated fatty acids that have in common a final carbon-carbon double bond in the omega-3 position, i.e., the third bond from the methyl end of the fatty acid. PMID:15129302 PMID:15253883 PMID:15555528 PMID:16741195 PMID:19154523 PMID:19439966 PMID:21975796 PMID:23643471 PMID:24012777 PMID:24122252 PMID:24128563 PMID:24172034 PMID:24211484 PMID:24240437 PMID:24246761 PMID:24281905 PMID:24397938 PMID:24401220 PMID:24418228 Wikipedia:Omega-3_fatty_acid omega-3 fatty acid chebi_ontology n-3 fatty acid n-3 fatty acids omega-3 fatty acids CHEBI:25681 omega-3 fatty acid chebi_ontology organic heteromonocyclic compounds CHEBI:25693 organic heteromonocyclic compound An organooxygen compound with formula ROR, where R is not hydrogen. 0 OR2 15.99940 15.99491 [*]O[*] ether ethers chebi_ontology ethers CHEBI:25698 ether Wikipedia:Organophosphate organic phosphate chebi_ontology organic phosphate ester organic phosphate esters organic phosphates organophosphate ester organophosphate esters CHEBI:25703 organic phosphate An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters. Wikipedia:Organophosphorus_compound organophosphorus compound chebi_ontology organophosphorus compounds CHEBI:25710 organophosphorus compound oxygen molecular entity chebi_ontology oxygen molecular entities CHEBI:25806 oxygen molecular entity aldopentose phosphate chebi_ontology aldopentose phosphates CHEBI:25900 aldopentose phosphate The nitrogen oxoanion formed by loss of a proton from peroxynitrous acid. -1 NO3 InChI=1S/HNO3/c2-1-4-3/h3H/p-1 CMFNMSMUKZHDEY-UHFFFAOYSA-M 62.00494 61.98837 [O-]ON=O CAS:19059-14-4 Gmelin:674445 KEGG:C16845 PMID:29051068 Wikipedia:Peroxynitrite azoperoxoite oxidoperoxidonitrate(1-) peroxynitrite chebi_ontology [NO(OO)](-) CHEBI:25941 peroxynitrite Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom. phosphates chebi_ontology phosphates CHEBI:26020 phosphate chebi_ontology CHEBI:26079 phosphoric acid derivative chebi_ontology phosphorus molecular entities CHEBI:26082 phosphorus molecular entity Any amino acid whose side chain is capable of forming one or more hydrogen bonds. 0 C2H4NO2R 74.059 74.02420 OC(C(*)N)=O CHEBI:8283 MetaCyc:Polar-amino-acids PMID:12016058 polar amino acid chebi_ontology polar amino acids polar amino-acid polar amino-acids CHEBI:26167 polar amino acid A compound that contains two or more hydroxy groups. chebi_ontology polyols CHEBI:26191 polyol Any fatty acid containing more than one double bond. Acids in this group are reported to have cardioprotective effects; and levels are lowered in chronic fatigue syndrome. PMID:14977874 PMID:16380690 PMID:17891522 chebi_ontology PUFA PUFAs polyunsaturated fatty acids CHEBI:26208 polyunsaturated fatty acid A symmetrical oxalamide-based bis-quaternary ammonium ion having ethyl and 2-chlorobenzyl groups attached to the nitrogens. +2 C28H42Cl2N4O2 InChI=1S/C28H40Cl2N4O2/c1-5-33(6-2,21-23-13-9-11-15-25(23)29)19-17-31-27(35)28(36)32-18-20-34(7-3,8-4)22-24-14-10-12-16-26(24)30/h9-16H,5-8,17-22H2,1-4H3/p+2 OMHBPUNFVFNHJK-UHFFFAOYSA-P 537.56500 536.26738 CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)Cc1ccccc1Cl)Cc1ccccc1Cl Beilstein:4168740 CAS:7648-98-8 DrugBank:DB01122 Drug_Central:146 KEGG:C07773 Wikipedia:Ambenonium 2,2'-[(1,2-dioxoethane-1,2-diyl)diimino]bis[N-(2-chlorobenzyl)-N,N-diethylethanaminium] Ambenonium chebi_ontology Ambenonium Base Ambenonum CHEBI:2627 ambenonium chebi_ontology CHEBI:26373 pteridines chebi_ontology CHEBI:26375 pterins Any nucleotide that has a purine nucleobase. chebi_ontology purine nucleotides CHEBI:26395 purine nucleotide Any ribonucleotide that has a purine nucleobase. chebi_ontology purine ribonucleotides CHEBI:26400 purine ribonucleotide A class of imidazopyrimidines that consists of purine and its substituted derivatives. 0 C5N4R7 116.080 116.01230 CHEBI:13678 chebi_ontology CHEBI:26401 purines A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraenoic acid substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified). 0 C20H28O2 InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22) SHGAZHPCJJPHSC-UHFFFAOYSA-N 300.43512 300.20893 CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O LINCS:LSM-2135 PMID:24506204 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid chebi_ontology CHEBI:26536 retinoic acid chebi_ontology ribonucleotides CHEBI:26561 ribonucleotide ribose phosphate chebi_ontology ribose phosphates CHEBI:26562 ribose phosphate Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). LIPID_MAPS_class:LMPR0103 chebi_ontology sesquiterpenoides sesquiterpenoids CHEBI:26658 sesquiterpenoid An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5. 0 C20H23N InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3 KRMDCWKBEZIMAB-UHFFFAOYSA-N 277.40336 277.18305 CN(C)CCC=C1c2ccccc2CCc2ccccc12 Beilstein:2217885 CAS:50-48-6 DrugBank:DB00321 Drug_Central:180 HMDB:HMDB0014466 KEGG:C06824 KEGG:D07448 LINCS:LSM-3190 PMID:15554244 PMID:18359012 PMID:24447704 Patent:CN101780063 Patent:WO2011089289 Reaxys:2217885 VSDB:2962 Wikipedia:Amitriptyline 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine Amitriptyline chebi_ontology 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene 5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene Amitriptylin CHEBI:2666 amitriptyline Sphingolipids are a complex family of compounds that share a common structural feature, a sphingoid base backbone. chebi_ontology sphingolipids CHEBI:26739 sphingolipid A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position. 0 C17H16ClN3O InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2 QWGDMFLQWFTERH-UHFFFAOYSA-N 313.78100 313.09819 Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1 Beilstein:832057 CAS:14028-44-5 DrugBank:DB00543 Drug_Central:191 KEGG:D00228 LINCS:LSM-2021 Patent:FR1508536 Patent:US3663696 Wikipedia:Amoxapine 2-chloro-11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazepine chebi_ontology 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine Desmethylloxapin amoxapina amoxapine amoxapinum CHEBI:2675 amoxapine Any steroid that acts as hormone. chebi_ontology Steroidhormon Steroidhormone hormona esteroide hormonas esteroideas hormone steroide hormones steroides steroid hormones CHEBI:26764 steroid hormone A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of succinic acid. chebi_ontology succinate anion succinates succinic acid anion CHEBI:26806 succinate chebi_ontology carbohydrate phosphates CHEBI:26816 carbohydrate phosphate sulfur molecular entity chebi_ontology sulfur molecular entities CHEBI:26835 sulfur molecular entity An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur. chebi_ontology thiocarboxylic esters CHEBI:26959 thiocarboxylic ester chebi_ontology CHEBI:26977 thiosulfate chebi_ontology heterobicyclic compounds organic heterobicyclic compounds CHEBI:27171 organic heterobicyclic compound Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms). Vitamin B6 chebi_ontology vitamin B-6 vitamin B6 vitamer vitamin B6 vitamers vitamina B6 vitamine B6 vitamins B6 CHEBI:27306 vitamin B6 0 Zn InChI=1S/Zn HCHKCACWOHOZIP-UHFFFAOYSA-N 65.39000 63.92914 [Zn] CAS:7440-66-6 Gmelin:16321 KEGG:C00038 PDBeChem:ZN WebElements:Zn zinc chebi_ontology 30Zn Zink Zn Zn(II) Zn2+ cinc zinc zincum CHEBI:27363 zinc atom An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation. 0 C19H19N7O6 InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1 OVBPIULPVIDEAO-LBPRGKRZSA-N 441.39750 441.13968 Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)nc2c(=O)[nH]1 CHEBI:24075 CHEBI:42610 CHEBI:5140 CHEBI:569217 AGR:IND606960789 Beilstein:100781 CAS:59-30-3 Chemspider:5815 DrugBank:DB00158 Drug_Central:1231 FooDB:FDB014504 HMDB:HMDB0000121 KEGG:C00504 KEGG:D00070 KNApSAcK:C00001539 LINCS:LSM-5355 MetaCyc:CPD-12826 PDBeChem:FOL PMID:10138938 PMID:10897644 PMID:10958818 PMID:11261364 PMID:11451208 PMID:11959400 PMID:14387833 PMID:15321809 PMID:15523939 PMID:15754725 PMID:15797531 PMID:15797685 PMID:15831910 PMID:15990733 PMID:16093404 PMID:16277678 PMID:16380297 PMID:16871332 PMID:17784727 PMID:18788725 PMID:19121630 PMID:19335717 PMID:19355913 PMID:24650098 PMID:33624660 PMID:33965562 PMID:33968971 PMID:34207319 PMID:34219855 PMID:7738698 PMID:8235383 PMID:9040515 PMID:9420019 PMID:9565830 PMID:9683174 PMID:9781393 PMID:9808640 PMID:9808641 Reaxys:100781 Wikipedia:Folic_Acid N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid chebi_ontology (2S)-2-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzamido)pentanedioic acid Acfol Folate Folicet Folsaeure N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid N-pteroyl-L-glutamic acid PGA PteGlu acide folique acido folico acidum folicum folic acid pteroyl-L-glutamic acid pteroyl-L-monoglutamic acid pteroylglutamic acid pteroylmonoglutamic acid vitamin B11 vitamin B9 vitamin Bc vitamin Be vitamin M CHEBI:27470 folic acid 0 C20H32O6 InChI=1S/C20H32O6/c1-2-3-6-9-15(24-23)12-13-17-16(18-14-19(17)26-25-18)10-7-4-5-8-11-20(21)22/h4,7,12-13,15-19,23H,2-3,5-6,8-11,14H2,1H3,(H,21,22)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 SGUKUZOVHSFKPH-YNNPMVKQSA-N 368.46448 368.21989 CCCCC[C@H](OO)\C=C\[C@H]1[C@H]2C[C@H](OO2)[C@@H]1C\C=C/CCCC(O)=O CHEBI:26329 CHEBI:44869 CHEBI:8519 CAS:51982-36-6 DrugBank:DB03866 KEGG:C05956 LIPID_MAPS_instance:LMFA03010009 (5Z)-7-{(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroperoxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid (5Z,9S,11R,13E,15S)-15-hydroperoxy-9,11-epidioxyprosta-5,13-dien-1-oic acid Prostaglandin G2 chebi_ontology PGG2 CHEBI:27647 prostaglandin G2 0 C63H91CoN13O14P InChI=1S/C62H90N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1 JEWJRMKHSMTXPP-WZHZPDAFSA-L 1344.38230 1343.58780 [H][C@]12[C@H](CC(N)=O)[C@@]3(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]4[C@@H](O)[C@H](O[C@@H]4CO)n4c[n+](c5cc(C)c(C)cc45)[Co-3]456(C)N1C3=C(C)C1=[N+]4C(=CC3=[N+]5C(=C(C)C4=[N+]6[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]3CCC(N)=O)C(C)(C)[C@@H]1CCC(N)=O CHEBI:25291 CHEBI:48831 CHEBI:6869 CAS:13422-55-4 COMe:MOL000085 DrugBank:DB03614 Gmelin:124528 KEGG:C06453 KEGG:D03246 PDBeChem:COB Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-methylcobamide Methylcobalamin methylcobalamin chebi_ontology CO-METHYLCOBALAMIN MeCbl mecobalamin methylcob(III)alamin CHEBI:28115 methylcobalamin An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4. 0 C5H10N2O3 InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10) ZDXPYRJPNDTMRX-UHFFFAOYSA-N 146.14458 146.06914 NC(CCC(N)=O)C(O)=O CHEBI:24316 CHEBI:5432 Beilstein:1723795 CAS:585-21-7 CAS:6899-04-3 Gmelin:27318 KEGG:C00303 KNApSAcK:C00001359 Reaxys:1723795 Wikipedia:Glutamine Glutamine glutamine chebi_ontology 2,5-diamino-5-oxopentanoic acid 2-Aminoglutaramic acid 2-amino-4-carbamoylbutanoic acid Glutamin Glutaminsaeure-5-amid Hgln glutamic acid gamma-amide CHEBI:28300 glutamine 0 C6H10OS2 InChI=1S/C6H10OS2/c1-3-5-8-9(7)6-4-2/h3-4H,1-2,5-6H2 JDLKFOPOAOFWQN-UHFFFAOYSA-N 162.27500 162.01731 C=CCSS(=O)CC=C CHEBI:22356 CHEBI:2595 Beilstein:1752823 CAS:539-86-6 KEGG:C07600 KNApSAcK:C00001242 Allicin S-allyl prop-2-ene-1-sulfinothioate chebi_ontology 2-Propene-1-sulfinothioic acid S-2-propenyl ester thio-2-propene-1-sulfinic acid S-allyl ester CHEBI:28411 allicin 0 Cu InChI=1S/Cu RYGMFSIKBFXOCR-UHFFFAOYSA-N 63.54600 62.92960 [Cu] CHEBI:23376 CHEBI:3874 CAS:7440-50-8 Gmelin:16269 KEGG:C00070 WebElements:Cu copper chebi_ontology 29Cu Copper Cu Kupfer cobre copper cuivre cuprum CHEBI:28694 copper atom A primary amino compound that is the 5-hydroxy derivative of tryptamine. 0 C10H12N2O InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 176.215 176.09496 C1=CC(=CC=2C(=CNC12)CCN)O CHEBI:1420 CHEBI:26652 CHEBI:49894 Beilstein:143524 CAS:50-67-9 Gmelin:1861995 HMDB:HMDB0000259 KEGG:C00780 KNApSAcK:C00001429 LINCS:LSM-6589 MetaCyc:SEROTONIN PDBeChem:SRO PMID:18593914 PMID:22770225 PMID:24136337 Reaxys:143524 Wikipedia:Serotonin 3-(2-aminoethyl)-1H-indol-5-ol SEROTONIN Serotonin chebi_ontology 3-(2-Aminoethyl)-1H-indol-5-ol 5-HT 5-Hydroxytryptamine Enteramine serotonine thrombocytin thrombotonin CHEBI:28790 serotonin An S-substituted L-cysteine where the S-substituent is specified as sulfanyl. 0 C3H7NO2S2 InChI=1S/C3H7NO2S2/c4-2(1-8-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1 XBKONSCREBSMCS-REOHCLBHSA-N 153.210 152.99182 C([C@H](N)C(=O)O)SS CHEBI:21269 CHEBI:41628 CHEBI:41711 CHEBI:41718 CHEBI:41743 CHEBI:9551 CAS:5652-32-4 DrugBank:DB02761 KEGG:C01962 PDBeChem:CSS PMID:10753862 PMID:10760256 PMID:12382038 PMID:12386155 PMID:12686149 PMID:14644425 PMID:16855700 PMID:9099686 PMID:9867829 RESID:AA0269 Reaxys:6381723 3-disulfanyl-L-alanine chebi_ontology (R)-2-amino-3-disulfanylpropanoic acid 2-amino-3-disulfanylpropanoic acid 2-amino-3-hydrodisulfidopropanoic acid 2-amino-3-hydropersulfidopropanoic acid 2-amino-3-persulfhydrylpropanoic acid 3-(thiosulfeno)-alanine S-sulfanylcysteine Thiocysteine cysteine persulfide cysteine perthiol thiocysteine CHEBI:28839 3-disulfanyl-L-alanine 0 Al InChI=1S/Al XAGFODPZIPBFFR-UHFFFAOYSA-N 26.98154 26.98154 [Al] CHEBI:22471 CHEBI:2616 CAS:7429-90-5 DrugBank:DB01370 Gmelin:16248 KEGG:C06264 WebElements:Al aluminium chebi_ontology 13Al Al Aluminium aluminio aluminium aluminum CHEBI:28984 aluminium atom An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group. 0 C6H14N4O2 InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10) ODKSFYDXXFIFQN-UHFFFAOYSA-N 174.20112 174.11168 NC(CCCNC(N)=N)C(O)=O CHEBI:22616 CHEBI:2643 Beilstein:1725411 CAS:7200-25-1 KEGG:C02385 PMID:10848923 Reaxys:1725411 Wikipedia:L-Arginine Arginine arginine chebi_ontology 2-Amino-5-guanidinovaleric acid 2-amino-5-(carbamimidamido)pentanoic acid 2-amino-5-guanidinopentanoic acid Arginin Harg CHEBI:29016 arginine +2 Fe InChI=1S/Fe/q+2 CWYNVVGOOAEACU-UHFFFAOYSA-N 55.84500 55.93384 [Fe++] CHEBI:13319 CHEBI:13321 CHEBI:21129 CHEBI:24876 CHEBI:34754 CHEBI:49599 CAS:15438-31-0 Gmelin:6845 KEGG:C14818 PDBeChem:FE2 Iron(2+) iron(2+) iron(2+) ion iron(II) cation chebi_ontology FE (II) ION Fe(2+) Fe(II) Fe2+ Ferrous ion iron ion(2+) CHEBI:29033 iron(2+) A monoatomic monocation obtained from sodium. +1 Na InChI=1S/Na/q+1 FKNQFGJONOIPTF-UHFFFAOYSA-N 22.98977 22.98922 [Na+] CHEBI:26717 CHEBI:49766 CHEBI:9175 CAS:17341-25-2 Gmelin:15196 KEGG:C01330 PDBeChem:NA sodium cation sodium(1+) sodium(1+) ion sodium(I) cation chebi_ontology Na(+) Na+ SODIUM ION CHEBI:29101 sodium(1+) A monoatomic monocation obtained from potassium. +1 K InChI=1S/K/q+1 NPYPAHLBTDXSSS-UHFFFAOYSA-N 39.09830 38.96316 [K+] CHEBI:26219 CHEBI:49685 CHEBI:8345 CAS:24203-36-9 Gmelin:15203 KEGG:C00238 KEGG:D08403 PDBeChem:K potassium cation potassium(1+) potassium(1+) ion potassium(I) cation chebi_ontology K(+) K+ POTASSIUM ION CHEBI:29103 potassium(1+) +2 Zn InChI=1S/Zn/q+2 PTFCDOFLOPIGGS-UHFFFAOYSA-N 65.39000 63.92804 [Zn++] CHEBI:10113 CHEBI:27368 CHEBI:49972 CHEBI:49982 CAS:23713-49-7 Gmelin:6869 KEGG:C00038 PDBeChem:ZN zinc(2+) zinc(2+) ion zinc(II) cation chebi_ontology ZINC ION Zn(2+) Zn(II) Zn2+ dietary zinc zinc cation zinc, ion (Zn2+) CHEBI:29105 zinc(2+) +2 Ca InChI=1S/Ca/q+2 BHPQYMZQTOCNFJ-UHFFFAOYSA-N 40.07800 39.96149 [Ca++] CHEBI:22988 CHEBI:3308 CHEBI:48760 CAS:14127-61-8 Gmelin:6850 KEGG:C00076 PDBeChem:CA calcium(2+) calcium(2+) ion calcium(II) cation chebi_ontology CALCIUM ION Ca(2+) Ca2+ calcium, doubly charged positive ion CHEBI:29108 calcium(2+) 0 HO InChI=1S/HO/h1H TUJKJAMUKRIRHC-UHFFFAOYSA-N 17.00734 17.00274 [O][H] CHEBI:24707 CHEBI:29190 CAS:3352-57-6 Gmelin:105 KEGG:C16844 hydridooxygen(.) hydroxyl oxidanyl chebi_ontology (OH)(.) HO(.) Hydrogen oxide hydroxyl radical CHEBI:29191 hydroxyl A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid. -1 C2H3O2 InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1 QTBSBXVTEAMEQO-UHFFFAOYSA-M 59.04402 59.01385 CC([O-])=O CHEBI:13704 CHEBI:22165 CHEBI:40480 Beilstein:1901470 CAS:71-50-1 DrugBank:DB03166 Gmelin:1379 KEGG:C00033 MetaCyc:ACET PDBeChem:ACT PMID:17190852 PMID:22211106 PMID:22371380 Reaxys:1901470 UM-BBD_compID:c0050 Wikipedia:Acetate acetate chebi_ontology ACETATE ION Azetat CH3-COO(-) Ethanoat MeCO2 anion acetic acid, ion(1-) ethanoate CHEBI:30089 acetate A benzazepine that is benazeprilat in which the carboxy group of the 2-amino-4-phenylbutanoic acid moiety has been converted to the corresponding ethyl ester. It is used (generally as its hydrochloride salt) as a prodrug for the angiotensin-converting enzyme inhibitor benazeprilat in the treatment of hypertension and heart failure. 0 C24H28N2O5 InChI=1S/C24H28N2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28)/t19-,20-/m0/s1 XPCFTKFZXHTYIP-PMACEKPBSA-N 424.48950 424.19982 CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCc2ccccc2N(CC(O)=O)C1=O CAS:86541-75-5 DrugBank:DB00542 Drug_Central:299 HMDB:HMDB0014682 KEGG:C06843 KEGG:D07499 LINCS:LSM-5609 MetaCyc:CPD-15329 PMID:25224804 PMID:25738503 PMID:25784709 PMID:25912588 Patent:EP72352 Patent:US4410520 Reaxys:4302258 Wikipedia:Benazepril Benazepril [(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid chebi_ontology 1H-1-Benzazepine-1-acetic acid, 3-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-, (S-(R*,R*))- benazepril benazeprilum CHEBI:3011 benazepril 0 Li InChI=1S/Li WHXSMMKQMYFTQS-UHFFFAOYSA-N 6.94100 7.01600 [Li] CAS:7439-93-2 WebElements:Li lithium chebi_ontology 3Li Li Lithium lithium litio CHEBI:30145 lithium atom CHEBI:13613 CHEBI:26918 chebi_ontology tetrahydropteridines tetrahydropterins CHEBI:30436 tetrahydropterin A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. 0 HOR 17.007 17.00274 O[*] CHEBI:13804 CHEBI:22288 CHEBI:2553 KEGG:C00069 Alcohol alcohols chebi_ontology an alcohol CHEBI:30879 alcohol Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration. KEGG:C01558 Bile acid chebi_ontology 5beta-bile acid 5beta-bile acids Bile salt Gallensaeure Gallensaeuren bile acids CHEBI:3098 bile acid An N-arylpiperazine that is piperazine substituted by a 4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl group at position 1 and by a 2,3-dichlorophenyl group at position 4. It is an antipsychotic drug used for the treatment of Schizophrenia, and other mood disorders. 0 C23H27Cl2N3O2 InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 448.390 447.14803 ClC1=C(Cl)C(=CC=C1)N1CCN(CCCCOC2=CC=C3CCC(=O)NC3=C2)CC1 CAS:129722-12-9 Chemspider:54790 DrugBank:DB01238 Drug_Central:242 FooDB:FDB004879 HMDB:HMDB0005042 KEGG:C12564 KEGG:D01164 LINCS:LSM-5776 PDBeChem:9SC PMID:12063084 PMID:12784105 PMID:14998222 PMID:15019558 PMID:15189766 PMID:15257633 PMID:15825673 PMID:16401666 PMID:16508892 PMID:16554739 PMID:16648324 PMID:16880478 PMID:17115868 PMID:17472545 PMID:17501690 PMID:18021764 PMID:18646161 PMID:18720421 PMID:18765484 PMID:18788833 PMID:19412463 PMID:19956463 PMID:20201815 PMID:30292748 PMID:30411049 PMID:30856161 PMID:31152368 PMID:31320322 PMID:32891516 PMID:33064050 PMID:33347031 Patent:EP367141 Patent:US5006528 Wikipedia:Aripiprazole 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one chebi_ontology 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone 7-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one Abilify Abilify Discmelt Abilify Maintena Abilify MyCite Abilitat Arpizol Asprito Discmelt OPC 14597 OPC 31 OPC-14597 OPC-31 Pripiprazole aripiprazol aripiprazole aripiprazolum CHEBI:31236 aripiprazole 0 C23H30FN3 InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3 XVGOZDAJGBALKS-UHFFFAOYSA-N 367.504 367.24238 FC1=CC=C(C=C1)C=2C3=C(N=C(C2)N4CCN(CC4)CC)CCCCCC3 CAS:132810-10-7 Drug_Central:388 KEGG:D01176 Blonanserin chebi_ontology AD 5423 AD-5423 lonasen CHEBI:31296 Blonanserin A member of the class of 1,4-benzoquinones which is substituted by methoxy groups at positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at positions 6. Initially developed for the treatment of Alzheimer's disease, benefits were modest; it was subsequently found to be of benefit for the symptomatic treatment of Friedreich's ataxia. 0 C19H30O5 InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3 JGPMMRGNQUBGND-UHFFFAOYSA-N 338.444 338.20932 COC1=C(OC)C(=O)C(CCCCCCCCCCO)=C(C)C1=O CAS:58186-27-9 Chemspider:3558 DrugBank:DB09081 Drug_Central:1416 KEGG:D01750 LINCS:LSM-5505 PMID:11207459 PMID:15374364 PMID:18045357 PMID:18710357 PMID:19283347 PMID:19283350 PMID:20955109 PMID:22269948 PMID:23859348 PMID:2669658 PMID:30726629 PMID:32111141 PMID:33247801 PMID:33254077 PMID:33628024 PMID:7981485 PMID:7988944 Patent:DE2519730 Patent:US4271083 Reaxys:2001459 Wikipedia:Idebenone 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone chebi_ontology 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone CV 2619 CV-2619 Raxone idebenona idebenone idebenonum CHEBI:31687 idebenone A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine. 0 C15H23N3O4S InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 341.42600 341.14093 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O CAS:15676-16-1 DrugBank:DB00391 Drug_Central:2537 KEGG:D01226 LINCS:LSM-5080 PMID:16327907 PMID:16924461 PMID:17912501 PMID:17942035 PMID:18757738 PMID:18985321 PMID:19370694 PMID:19546258 PMID:19672580 PMID:19864199 PMID:19941957 PMID:20061345 PMID:20091661 PMID:20177884 PMID:20304506 PMID:20305607 PMID:20538381 PMID:20599913 PMID:20875676 Patent:DE2903891 Patent:US3342826 Reaxys:494008 Wikipedia:Sulpiride N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide chebi_ontology (+-)-sulpiride 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide Sulpirid Sulpyrid sulpirida sulpiride sulpiridum CHEBI:32168 sulpiride A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain and inflammation in osteoarthritis and rheumatoid arthritis. It is also indicated for short term treatment of acute musculoskeletal disorders including strains, sprains and other soft-tissue injuries. 0 C13H11N3O4S2 InChI=1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18) LZNWYQJJBLGYLT-UHFFFAOYSA-N 337.37400 337.01910 CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O CAS:59804-37-4 DrugBank:DB00469 Drug_Central:2595 KEGG:D01767 PMID:21129461 PMID:21327813 PMID:21682312 PMID:21712619 PMID:21777594 PMID:21929527 PMID:21981557 PMID:22095696 PMID:22182582 PMID:22306394 PMID:22675955 PMID:22841852 PMID:22876956 PMID:23204620 PMID:23273940 PMID:23340327 PMID:23480456 PMID:23656309 PMID:23932198 PMID:24037655 PMID:24093711 PMID:28166217 Patent:US2008014272 Patent:US4687766 Reaxys:572193 Wikipedia:Tenoxicam 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide chebi_ontology Mobiflex Tilcotil tenoxicam tenoxicamum CHEBI:32192 tenoxicam An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. CHEBI:22473 CHEBI:2633 KEGG:C00241 Amide amides chebi_ontology CHEBI:32988 amide A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines. CHEBI:10004 CHEBI:27305 Wikipedia:Vitamin chebi_ontology vitamin vitamina vitaminas vitamine vitamines vitamins vitaminum CHEBI:33229 vitamin (role) Intended use of the molecular entity or part thereof by humans. chebi_ontology CHEBI:33232 application Any member of a group of fat-soluble chromanols that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen. MetaCyc:Vitamin-E PMID:33684201 PMID:33847203 PMID:33896432 PMID:34277234 PMID:34278890 PMID:7898412 PMID:7901680 Wikipedia:Vitamin_E vitamin E chebi_ontology vitamin E vitamer vitamin E vitamers vitamin-E vitamins E CHEBI:33234 vitamin E chebi_ontology oxoacid derivatives CHEBI:33241 oxoacid derivative A chemical entity constituting the smallest component of an element having the chemical properties of the element. CHEBI:22671 CHEBI:23907 atom chebi_ontology atome atomo atoms atomus element elements CHEBI:33250 atom A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. primary amide primary amides chebi_ontology CHEBI:33256 primary amide An organosulfur compound is a compound containing at least one carbon-sulfur bond. CHEBI:23010 CHEBI:25714 Wikipedia:Organosulfur_compounds organosulfur compound chebi_ontology organosulfur compounds CHEBI:33261 organosulfur compound chebi_ontology chemical messenger CHEBI:33280 molecular messenger A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms. chebi_ontology heteroorganic entities organoelement compounds CHEBI:33285 heteroorganic entity A molecular entity containing one or more atoms of an alkali metal. chebi_ontology alkali metal molecular entities CHEBI:33296 alkali metal molecular entity A p-block molecular entity containing any pnictogen. pnictogen molecular entity chebi_ontology pnictogen molecular entities CHEBI:33302 pnictogen molecular entity Any p-block molecular entity containing a chalcogen. chalcogen molecular entity chebi_ontology chalcogen compounds chalcogen molecular entities CHEBI:33304 chalcogen molecular entity An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl. 0 CO2R2 44.010 43.98983 [*]C(=O)O[*] CHEBI:13204 CHEBI:23028 CHEBI:3408 KEGG:C02391 Wikipedia:Ester Carboxylic ester carboxylic esters chebi_ontology a carboxylic ester carboxylic acid esters CHEBI:33308 carboxylic ester Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid. CHEBI:15132 CHEBI:25406 CHEBI:26086 CHEBI:9320 KEGG:C00934 PMID:18186488 phospho sugar chebi_ontology monosaccharide phosphates phospho sugars phosphorylated sugar phosphorylated sugars phosphosugar phosphosugars CHEBI:33447 phospho sugar 4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. 0 C8H9NO2R2 151.163 151.06333 CHEBI:23056 CHEBI:3468 KEGG:C02012 Catecholamine catecholamines chebi_ontology catecholamines CHEBI:33567 catecholamine A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted. 0 C8H11NO3 InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2 SFLSHLFXELFNJZ-UHFFFAOYSA-N 169.17788 169.07389 NCC(O)c1ccc(O)c(O)c1 Beilstein:2210994 CAS:138-65-8 Gmelin:863925 LINCS:LSM-5181 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol chebi_ontology noradrenalina norepinephrine CHEBI:33569 noradrenaline A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid. 0 CHO2R 45.01740 44.99765 OC([*])=O CHEBI:13428 CHEBI:13627 CHEBI:23027 PMID:17147560 PMID:18433345 Wikipedia:Carboxylic_acid carboxylic acid carboxylic acids chebi_ontology Carbonsaeure Carbonsaeuren Karbonsaeure RC(=O)OH acide carboxylique acides carboxyliques acido carboxilico acidos carboxilicos CHEBI:33575 carboxylic acid A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table. chebi_ontology main group compounds main group molecular entities CHEBI:33579 main group molecular entity carbon group molecular entity chebi_ontology carbon group molecular entities CHEBI:33582 carbon group molecular entity Any molecule that consists of a series of atoms joined together to form a ring. Wikipedia:Cyclic_compound chebi_ontology cyclic compounds CHEBI:33595 cyclic compound A cyclic compound having as ring members atoms of the same element only. homocyclic compound homocyclic compounds chebi_ontology isocyclic compounds CHEBI:33597 homocyclic compound A homocyclic compound in which all of the ring members are carbon atoms. carbocyclic compound carbocyclic compounds chebi_ontology carbocycle CHEBI:33598 carbocyclic compound chebi_ontology hydrogen compounds hydrogen molecular entities CHEBI:33608 hydrogen molecular entity chebi_ontology polycyclic compounds CHEBI:33635 polycyclic compound A molecule that features two fused rings. chebi_ontology bicyclic compounds CHEBI:33636 bicyclic compound A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character. aromatic compounds aromatic molecular entity chebi_ontology aromatics aromatische Verbindungen CHEBI:33655 aromatic compound chebi_ontology organic aromatic compounds CHEBI:33659 organic aromatic compound chebi_ontology monocyclic compounds CHEBI:33661 monocyclic compound heteromonocyclic compound heteromonocyclic compounds chebi_ontology CHEBI:33670 heteromonocyclic compound A polycyclic compound in which at least one of the rings contains at least one non-carbon atom. heteropolycyclic compounds chebi_ontology polyheterocyclic compounds CHEBI:33671 heteropolycyclic compound A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom. heterobicyclic compounds chebi_ontology CHEBI:33672 heterobicyclic compound An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element. s-block molecular entity chebi_ontology s-block compounds s-block molecular entities CHEBI:33674 s-block molecular entity A main group molecular entity that contains one or more atoms of a p-block element. chebi_ontology p-block compounds p-block molecular entities p-block molecular entitiy CHEBI:33675 p-block molecular entity A macromolecule formed by a living organism. biopolymer chebi_ontology Biopolymere biomacromolecules biopolymers CHEBI:33694 biomacromolecule chebi_ontology genetically encoded biomacromolecules genetically encoded biopolymers information biomacromolecules information biopolymers information macromolecule information macromolecules CHEBI:33695 information biomacromolecule High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins. CAS:63231-63-0 ribonucleic acid ribonucleic acids chebi_ontology RNA RNS Ribonukleinsaeure pentosenucleic acids ribonucleic acids ribose nucleic acid yeast nucleic acid CHEBI:33697 ribonucleic acid A L-proline derivative in which L-proline is substituted on nitrogen with a (2S)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug. 0 C9H15NO3S InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1 FAKRSMQSSFJEIM-RQJHMYQMSA-N 217.28500 217.07726 C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O Beilstein:477887 CAS:62571-86-2 DrugBank:DB01197 Drug_Central:484 KEGG:D00251 LINCS:LSM-5648 PMID:23137627 PMID:23161035 PMID:23278692 PMID:23299024 PMID:23328620 PMID:23397376 PMID:23410042 PMID:23422724 PMID:23429803 PMID:23435971 PMID:2420897 Patent:US4046889 Patent:US4105776 Wikipedia:Captopril 1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline chebi_ontology (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid Acepress Apopril CP Capoten Captolane Captopryl Captoril Cesplon D-2-methyl-3-mercaptopropanoyl-L-proline D-3-mercapto-2-methylpropanoyl-L-proline Dilabar Garranil Hypertil L-Captopril Lopirin Tenosbon TensoboInOwln Tensoprel captopril captoprilum CHEBI:3380 captopril An organic compound having at least one hydroxy group attached to a carbon atom. CHEBI:64710 hydroxy compounds chebi_ontology organic alcohol organic hydroxy compounds CHEBI:33822 organic hydroxy compound Any organic molecule that consists of atoms connected in the form of a ring. chebi_ontology organic cyclic compounds CHEBI:33832 organic cyclic compound A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2). heteroarenes chebi_ontology hetarenes CHEBI:33833 heteroarene chebi_ontology benzenoid aromatic compounds benzenoid compound CHEBI:33836 benzenoid aromatic compound A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Wikipedia:Macromolecule macromolecule chebi_ontology macromolecules polymer polymer molecule polymers CHEBI:33839 macromolecule Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. 0 C6HOR5 89.072 89.00274 C1(=C(C(=C(C(=C1*)*)*)*)*)O CHEBI:13664 CHEBI:13825 CHEBI:25969 CHEBI:2857 KEGG:C15584 MetaCyc:Phenols Wikipedia:Phenols phenols chebi_ontology Aryl alcohol a phenol arenols CHEBI:33853 phenols A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant. 0 C15H12N2O InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18) FFGPTBGBLSHEPO-UHFFFAOYSA-N 236.26860 236.09496 NC(=O)N1c2ccccc2C=Cc2ccccc12 CHEBI:115086 Beilstein:1246090 CAS:298-46-4 DrugBank:DB00564 Drug_Central:489 HMDB:HMDB0014704 KEGG:C06868 KEGG:D00252 LINCS:LSM-3610 PMID:10411478 PMID:11071486 PMID:11129121 PMID:11240598 PMID:11475584 PMID:11595204 PMID:11888243 PMID:11891095 PMID:12073283 PMID:12228880 PMID:12475188 PMID:12749779 PMID:12799799 PMID:12957643 PMID:14160216 PMID:14572037 PMID:14581052 PMID:14713026 PMID:14723323 PMID:15165631 PMID:15557493 PMID:15665743 PMID:15683742 PMID:15739418 PMID:15820347 PMID:15850602 PMID:16033627 PMID:16150575 PMID:16245817 PMID:16380297 PMID:16394456 PMID:16437428 PMID:16538175 PMID:16562645 PMID:16616830 PMID:16990009 PMID:17027750 PMID:17028629 PMID:17207414 PMID:17582711 PMID:17873967 PMID:17949959 PMID:18163657 PMID:18415623 PMID:18637155 PMID:18652684 PMID:18656520 PMID:18969759 PMID:19135617 PMID:19473818 PMID:19741433 PMID:19921623 PMID:22322005 PMID:27967303 PMID:7602118 Patent:US2004220187 Patent:US2007167446 Patent:US2011177136 Patent:US2011245283 Patent:US2948718 Reaxys:1246090 Wikipedia:Carbamazepine 5H-dibenzo[b,f]azepine-5-carboxamide chebi_ontology 5-Carbamoyl-5H-dibenz(b,f)azepine 5-Carbamoyl-5H-dibenzo(b,f)azepine 5-Carbamyl-5H-dibenzo(b,f)azepine 5-carbamoyl-5H-dibenz[b,f]azepine 5H-Dibenz(b,f)azepine-5-carboxamide Carbamazepen Carnexiv carbamazepina carbamazepine carbamazepinum CHEBI:3387 carbamazepine A mixture of hydrogenated ergot alkaloids consisting of the methanesulfonic acid salts of dihydroergocornine (R = CHMe2), dihydroergocristine (R = CH2Ph), and alpha- and beta-dihydroergocryptine (R = CH2CHMe2 and CH(Me)Et, respectively). It is used for the symptomatic treatment of mild to moderate dementia in the elderly, although its value is not established. 0 C29H38N5O8SR 616.708 616.24411 C1=CC=C2NC=C3C[C@@]4([C@](C[C@H](CN4C)C(N[C@]5(C(N6[C@@](O5)([C@]7(N(C([C@@H]6*)=O)CCC7)[H])O)=O)C(C)C)=O)(C1=C32)[H])[H].OS(C)(=O)=O Beilstein:8896265 CAS:8067-24-1 DrugBank:DB01049 KEGG:C14055 KEGG:D02268 chebi_ontology Dihydroergotoxine mesilate Dihydroergotoxine mesylate Ergoloid mesylates co-dergocrine mesilate co-dergocrine mesylate co-dergocrine methanesulfonate codergocrine mesilate codergocrine mesylate codergocrine methanesulfonate dihydroergotoxine methanesulfonate dihydroergotoxine methanesulfonates dihydroergotoxine monomethanesulfonate dihydrogenated ergot alkaloids ergoloid mesylates ergoloid methanesulfonate ergoloid methanesulfonates hydrogenated ergot alkaloids CHEBI:34706 ergoloid mesylate chebi_ontology aldose phosphates CHEBI:35131 aldose phosphate A substance that diminishes the rate of a chemical reaction. inhibitor chebi_ontology inhibidor inhibiteur inhibitors CHEBI:35222 inhibitor Any heteroorganic entity containing at least one carbon-nitrogen bond. organonitrogen compounds chebi_ontology organonitrogens CHEBI:35352 organonitrogen compound An amide of a sulfonic acid RS(=O)2NR'2. 0 NO2SR3 78.07100 77.96497 [*]S(=O)(=O)N([*])[*] PMID:11498380 PMID:2434548 PMID:26811268 PMID:26832216 Wikipedia:Sulfonamide sulfonamides chebi_ontology sulfonamides CHEBI:35358 sulfonamide Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. 0 CHO2R 45.01740 44.99765 OC([*])=O CHEBI:13633 CHEBI:24024 CHEBI:4984 KEGG:C00162 PMID:14287444 PMID:14300208 PMID:14328676 Wikipedia:Fatty_acid Fatty acid fatty acids chebi_ontology Fettsaeure Fettsaeuren acide gras acides gras acido graso acidos grasos fatty acids CHEBI:35366 fatty acid Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. chebi_ontology antidepressant drugs antidepressants thymoanaleptics thymoleptic drugs thymoleptics CHEBI:35469 antidepressant A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. chebi_ontology CNS agent CNS drugs central nervous system agents CHEBI:35470 central nervous system drug A loosely defined grouping of drugs that have effects on psychological function. Wikipedia:Psychotropic_drug chebi_ontology psychoactive agent psychoactive drugs psychopharmaceuticals psychotropic drugs CHEBI:35471 psychotropic drug A substance that reduces or suppresses inflammation. chebi_ontology anti-inflammatory drugs antiinflammatory agent antiinflammatory drug antiinflammatory drugs CHEBI:35472 anti-inflammatory drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. chebi_ontology anti-anxiety agents anti-anxiety drugs anxiolytic agents anxiolytics minor tranquilisers minor tranquilizers minor tranquilizing agents CHEBI:35474 anxiolytic drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Wikipedia:Non-steroidal_anti-inflammatory_drug chebi_ontology NSAID NSAIDs non-steroidal anti-inflammatory agent non-steroidal anti-inflammatory drugs CHEBI:35475 non-steroidal anti-inflammatory drug Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. chebi_ontology Neuroleptikum antipsychotic agents antipsychotic drug antipsychotic drugs antipsychotics antipsychotiques grosser Tranquilizer major tranquilizers major tranquilizing agents neuroleptic neuroleptic agents neuroleptics neuroleptique neuroleptiques CHEBI:35476 antipsychotic agent (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity. 0 C26H34FNO5 InChI=1S/C26H34FNO5/c1-15(2)25-21(11-10-19(29)12-20(30)13-23(31)32)24(17-6-8-18(27)9-7-17)22(14-33-5)26(28-25)16(3)4/h6-11,15-16,19-20,29-30H,12-14H2,1-5H3,(H,31,32)/b11-10+/t19-,20-/m1/s1 SEERZIQQUAZTOL-ANMDKAQQSA-N 459.55030 459.24210 COCc1c(nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)c1-c1ccc(F)cc1)C(C)C CHEBI:503465 Beilstein:8366578 CAS:145599-86-6 DrugBank:DB00439 Drug_Central:577 KEGG:C07966 KEGG:D07661 PMID:17560788 PMID:18155906 Wikipedia:Cerivastatin (3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid Cerivastatin chebi_ontology (3R,5S,6E)-7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-6-heptenoic acid (3R,5S,6E)-7-(4-(p-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoic acid (3R,5S,E)-7-(4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl)-3,5-dihydroxyhept-6-enoic acid cerivastatin cerivastatin acid CHEBI:3558 cerivastatin chebi_ontology carbon oxoacids oxoacids of carbon CHEBI:35605 carbon oxoacid 0 C10H17NOS InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8?,10-/m1/s1 WUTYZMFRCNBCHQ-LHIURRSHSA-N 199.31412 199.10309 CC1O[C@@]2(CS1)CN1CCC2CC1 CAS:107233-08-9 DrugBank:DB00185 KEGG:D00661 KEGG:D07667 Wikipedia:Cevimeline (2R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] (2R)-2'-methylspiro[4-quinuclidine -2,5'-[1,3]oxathiolane] chebi_ontology 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine Sni 2011 cevimelina cevimeline cevimelinum CHEBI:3568 cevimeline A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter. CHEBI:23960 CHEBI:4859 KEGG:C00287 Wikipedia:Ester Ester chebi_ontology esters CHEBI:35701 ester Any member of the group of lipids containing a common glycerol backbone to which at least one fatty acid-derived group is attached. PMID:18606873 chebi_ontology glycerolipids CHEBI:35741 glycerolipid An organosulfur compound having the structure RS(=O)2R (R =/= H). sulfone chebi_ontology sulfones CHEBI:35850 sulfone chebi_ontology imidazopyrimidines CHEBI:35875 imidazopyrimidine Any C22 polyunsaturated fatty acid containing six double bonds. 0 C22H32O2 328.489 328.24023 docosahexaenoic acid chebi_ontology DHA docosahexaenoic acids CHEBI:36005 docosahexaenoic acid A family of polyunsaturated fatty acids that have in common a final carbon-carbon double bond in the n-6 position, i.e., the sixth bond from the methyl end of the fatty acid. PMID:19035453 PMID:19136835 omega-6 fatty acid chebi_ontology omega-6 fatty acids CHEBI:36009 omega-6 fatty acid A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome. CHEBI:13677 CHEBI:14911 proteins chebi_ontology CHEBI:36080 protein Any glycerophospholipid having the polar alcohol inositol esterified to the phosphate group at the sn-3 position of the glycerol backbone. CHEBI:26040 CHEBI:35770 PMID:14706866 chebi_ontology GPI glycerophosphoinositols CHEBI:36315 glycerophosphoinositol Any molecular entity consisting of more than one atom. chebi_ontology polyatomic entities CHEBI:36357 polyatomic entity phosphorus oxoacid derivative chebi_ontology CHEBI:36359 phosphorus oxoacid derivative chebi_ontology CHEBI:36360 phosphorus oxoacids and derivatives A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety. 0 C17H19ClN2S InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 318.86400 318.09575 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 Beilstein:289793 CAS:50-53-3 DrugBank:DB00477 Drug_Central:621 HMDB:HMDB0014620 KEGG:C06906 KEGG:D00270 LINCS:LSM-4017 PDBeChem:Z80 PMID:14354584 PMID:14404586 PMID:15170372 PMID:1650428 PMID:16653219 PMID:20825390 PMID:2427628 PMID:7192992 Patent:US2645640 Reaxys:289793 Wikipedia:Chlorpromazine 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine Chlorpromazine chebi_ontology 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine Aminazine CPZ Chlorderazin Chloropromazine Chlorpromados Contomin Largactil N-(3-dimethylaminopropyl)-3-chlorophenothiazine Thorazine chlorpromazine chlorpromazinum clorpromazina CHEBI:3647 chlorpromazine 0 C18H18ClNS InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3 WSPOMRSOLSGNFJ-UHFFFAOYSA-N 315.86000 315.08485 [H]C(CCN(C)C)=C1c2ccccc2Sc2ccc(Cl)cc12 Beilstein:89898 CAS:113-59-7 DrugBank:DB01239 KEGG:C07953 KEGG:D00790 LINCS:LSM-3310 Patent:GB829763 Patent:US3046283 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine Chlorprothixene chebi_ontology Alpha-Chlorprothixene Chlorprothixen Chlorprothixine Chlorprotixen Chlorprotixene Chlorprotixine Chlothixen chlorprothixene chlorprothixenum clorprotixeno CHEBI:3651 chlorprothixene Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. carbonyl compounds chebi_ontology CHEBI:36586 carbonyl compound Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element. oxo compounds chebi_ontology organic oxo compounds CHEBI:36587 organic oxo compound A 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile that has S-configuration at the chiral centre. It is the active enantiomer of citalopram. 0 C20H21FN2O InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1 WSEQXVZVJXJVFP-FQEVSTJZSA-N 324.39202 324.16379 CN(C)CCC[C@]1(OCc2cc(ccc12)C#N)c1ccc(F)cc1 Beilstein:9001444 CAS:128196-01-0 DrugBank:DB01175 Drug_Central:1053 HMDB:HMDB0005028 KEGG:D07913 LINCS:LSM-3569 PMID:14501259 PMID:14594439 PMID:14708881 PMID:15200745 PMID:15609164 PMID:16266205 PMID:16421462 PMID:16937393 PMID:16953656 PMID:18789789 PMID:19710642 PMID:20825390 PMID:24172161 PMID:24176515 PMID:24289655 PMID:24424469 PMID:24469525 PMID:24528284 Wikipedia:Escitalopram (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile chebi_ontology (+)-citalopram (S)-citalopram Esertia S(+)-citalopram S-(+)-citalopram escitalopram escitalopramum CHEBI:36791 escitalopram 0 C18H19NOS InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3 ZEUITGRIYCTCEM-UHFFFAOYSA-N 297.41560 297.11874 CNCCC(Oc1cccc2ccccc12)c1cccs1 Beilstein:8842375 CAS:116539-58-3 PMID:20825390 N-methyl-3-(naphthalen-1-yloxy)-3-(2-thienyl)propan-1-amine chebi_ontology N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine CHEBI:36796 duloxetine Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved. ring assemblies ring assembly chebi_ontology CHEBI:36820 ring assembly An organochalcogen compound is a compound containing at least one carbon-chalcogen bond. organochalcogen compound chebi_ontology organochalcogen compounds CHEBI:36962 organochalcogen compound An organochalcogen compound containing at least one carbon-oxygen bond. PMID:17586126 organooxygen compound chebi_ontology organooxygen compounds CHEBI:36963 organooxygen compound A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid. CHEBI:13215 CHEBI:13663 CHEBI:7656 KEGG:C00215 Wikipedia:Nucleotide Nucleotide chebi_ontology nucleotides CHEBI:36976 nucleotide A pyridazinodiazepine resulting from the formal condensation of the carboxy group of cilazaprilat with ethanol. It is a drug used in the treatment of hypertension and heart failure. 0 C22H31N3O5 InChI=1S/C22H31N3O5/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,27,28)/t17-,18-,19-/m0/s1 HHHKFGXWKKUNCY-FHWLQOOXSA-N 417.506 417.22637 C1CC[C@@H](C(N2N1CCC[C@H]2C(=O)O)=O)N[C@H](C(OCC)=O)CCC3=CC=CC=C3 CAS:88768-40-5 DrugBank:DB01340 Drug_Central:641 HMDB:HMDB0015433 KEGG:D07699 PMID:18297254 PMID:1836986 PMID:21760854 PMID:24383331 PMID:24754013 PMID:25272892 PMID:28334985 PMID:28445944 PMID:31531043 Wikipedia:Cilazapril (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid chebi_ontology Cilazapril anhydrous Dynorm Inhibace Ro 34-2848 Vascace Vascase cilazapril cilazaprilum CHEBI:3698 cilazapril chebi_ontology nucleoside bisphosphates CHEBI:37123 nucleoside bisphosphate An organofluorine compound is a compound containing at least one carbon-fluorine bond. 0 FR 18.998 18.99840 *F MetaCyc:Fluorides organofluorine compound chebi_ontology fluoroorganic compound fluoroorganic compounds fluoroorganics fluororganische Verbindungen organofluorine compounds CHEBI:37143 organofluorine compound chebi_ontology organic hydrides CHEBI:37175 organic hydride A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active. 0 C20H21FN2O 324.393 324.16379 Beilstein:1397373 CAS:59729-33-8 DrugBank:DB00215 HMDB:HMDB0005038 KEGG:C07572 KEGG:D07704 PMID:11336616 PMID:18213744 PMID:18219053 PMID:19747949 PMID:20825390 Patent:DE2657013 Patent:EP0171943 Patent:EP1506963 Patent:US4136193 Reaxys:1397373 Wikipedia:Citalopram Citalopram rac-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile chebi_ontology 1,3-dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile 1-(3-(dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile Cipram Citadur Lu 10-171 Nitalapram citalopram citalopramum CHEBI:3723 citalopram chebi_ontology adenosine 3',5'-bisphosphates CHEBI:37240 adenosine 3',5'-bisphosphate An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any fatty acid. 0 C22H35N7O17P3SR 794.53600 794.10230 CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC([*])=O CHEBI:24025 CHEBI:4987 PMID:11524729 PMID:20442897 PMID:2079609 chebi_ontology Fatty acyl CoA fatty acyl-coenzyme A fatty acyl-coenzyme As CHEBI:37554 fatty acyl-CoA An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of any alpha,omega-dicarboxylic acid. CHEBI:10614 CHEBI:13782 CHEBI:25688 KEGG:C03188 omega-Carboxyacyl-CoA omega-carboxyacyl-CoA chebi_ontology CHEBI:37555 omega-carboxyacyl-CoA 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation. 0 C15H10ClN3O3 InChI=1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7H,8H2,(H,18,20) DGBIGWXXNGSACT-UHFFFAOYSA-N 315.71100 315.04107 [O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1 CHEBI:102465 Beilstein:759557 CAS:1622-61-3 DrugBank:DB01068 Drug_Central:703 KEGG:D00280 PMID:10633040 PMID:12213069 PMID:12873507 Patent:US3116203 Patent:US3121076 Patent:US3335181 Wikipedia:Clonazepam 5-(2-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one CLONAZEPAM chebi_ontology 1,3-dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one 5-(2-Chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one 5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one 5-(o-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one clonazepam clonazepamum CHEBI:3756 clonazepam A molecular entity consisting of two or more chemical elements. chebi_ontology chemical compound heteroatomic molecular entities CHEBI:37577 heteroatomic molecular entity Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements. Wikipedia:Halide chebi_ontology halides CHEBI:37578 halide A lactone having a five-membered lactone ring. 0 C4H3O2R3 83.066 83.01330 O1C(C(C(C1=O)*)*)* CHEBI:13194 CHEBI:18937 CHEBI:22971 CHEBI:541 PMID:18789684 chebi_ontology 1,4-Lactone 1,4-lactones a 1,4-lactone butyrolactones gamma-Laktone gamma-lactona gamma-lactonas gamma-lactones CHEBI:37581 gamma-lactone An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom. 0 CNOR3 42.01680 41.99799 [*]C(=O)N([*])[*] CHEBI:35354 CHEBI:35355 carboxamides chebi_ontology carboxamides primary carboxamide CHEBI:37622 carboxamide A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia. 0 C18H19ClN4 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 326.824 326.12982 N1=C(C2=CC=CC=C2NC3=CC=C(C=C13)Cl)N4CCN(CC4)C Beilstein:0764984 CAS:5786-21-0 DrugBank:DB00363 Drug_Central:722 HMDB:HMDB0014507 KEGG:C06924 KEGG:D00283 PMID:18690109 PMID:18766167 PMID:20825390 PMID:24219174 Patent:FR1334944 Patent:NL293201 Patent:US3539573 Reaxys:764984 Wikipedia:Clozapine 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Clozapine chebi_ontology Clozapin clozapina clozapine clozapinum CHEBI:3766 clozapine CHEBI:26019 chebi_ontology CHEBI:37734 phosphoric ester Any glycerolipid having a phosphate group ester-linked to a terminal carbon of the glycerol backbone. CHEBI:24362 CHEBI:5456 PMID:17393491 chebi_ontology glycerophospholipids phosphatide phosphatides phosphoglyceride phosphoglycerides CHEBI:37739 glycerophospholipid chebi_ontology CHEBI:38093 phenothiazines Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms. chebi_ontology heterocyclic organonitrogen compounds organonitrogen heterocyclic compounds CHEBI:38101 organonitrogen heterocyclic compound Any organic heterocyclic compound containing at least one ring oxygen atom. PMID:17134300 chebi_ontology heterocyclic organooxygen compounds organooxygen heterocyclic compounds oxacycles CHEBI:38104 oxacycle CHEBI:25429 CHEBI:38075 chebi_ontology organic heteropolycyclic compounds CHEBI:38166 organic heteropolycyclic compound An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. Wikipedia:Acetylcholinesterase_inhibitor chebi_ontology AChEI AcCholE inhibitor AcCholE inhibitors EC 3.1.1.7 (acetylcholinesterase) inhibitors EC 3.1.1.7 inhibitor EC 3.1.1.7 inhibitors acetyl.beta-methylcholinesterase inhibitor acetyl.beta-methylcholinesterase inhibitors acetylcholine acetylhydrolase inhibitor acetylcholine acetylhydrolase inhibitors acetylcholine esterase inhibitor acetylcholine hydrolase inhibitor acetylcholine hydrolase inhibitors acetylcholinesterase (EC 3.1.1.7) inhibitor acetylcholinesterase (EC 3.1.1.7) inhibitors acetylcholinesterase inhibitor acetylcholinesterase inhibitors acetylthiocholinesterase inhibitor acetylthiocholinesterase inhibitors choline esterase I inhibitor choline esterase I inhibitors cholinesterase inhibitor cholinesterase inhibitors true cholinesterase inhibitor true cholinesterase inhibitors CHEBI:38462 EC 3.1.1.7 (acetylcholinesterase) inhibitor A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer). 0 C22H28FN3O6S InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1 BPRHUIZQVSMCRT-VEUZHWNKSA-N 481.53800 481.16828 CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O Beilstein:9670765 CAS:287714-41-4 DrugBank:DB01098 Drug_Central:2406 HMDB:HMDB0015230 KEGG:D08492 PMID:17970755 PMID:18509206 PMID:19724024 PMID:19956889 PMID:23806820 PMID:23881596 PMID:23944632 PMID:24072337 PMID:24076283 PMID:24076297 PMID:24156555 PMID:24163149 PMID:24230979 PMID:24253250 PMID:24259612 PMID:24304551 PMID:24333476 PMID:24353409 PMID:24410968 PMID:24417785 PMID:24434545 PMID:24440231 PMID:24440960 PMID:24444439 PMID:24452083 PMID:24456217 PMID:24467235 Patent:US2013035316 Reaxys:9670765 Wikipedia:Rosuvastatin (3R,5S,6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid chebi_ontology (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid rosuvastatin CHEBI:38545 rosuvastatin A racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. An HMG-CoA reductase inhibitor, it is used (often as the corresponding sodium salt) to reduce triglycerides and LDL-cholesterol, and increase HDL-chloesterol, in the treatment of hyperlipidaemia. 0 C24H26FNO4 InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m0/s1 FJLGEFLZQAZZCD-JUFISIKESA-N 411.467 411.18459 C1(=CC=C(C=C1)C=2C=3C(N(C2/C=C/[C@@H](C[C@@H](CC(O)=O)O)O)C(C)C)=CC=CC3)F Beilstein:9168031 CAS:93957-54-1 DrugBank:DB01095 KEGG:C07014 KEGG:D07983 PMID:11273020 PMID:12147804 PMID:18410471 PMID:18413661 PMID:18452779 PMID:18936176 PMID:23212095 PMID:23846727 Patent:US4739073 Patent:WO8402131 Wikipedia:Fluvastatin rac-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid chebi_ontology (+-)-fluvastatin (6E)-erythro7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid Cranoc erythro-(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indol-2'-yl]hept-6-enoic acid fluvastatin fluvastatina fluvastatine fluvastatinum rac-(3R,5S)-fluvastatin rac-(3R,5S,6E)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid CHEBI:38561 fluvastatin 0 C15H13FO2 InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1 SYTBZMRGLBWNTM-SNVBAGLBSA-N 244.26092 244.08996 C[C@@H](C(O)=O)c1ccc(c(F)c1)-c1ccccc1 Beilstein:4686157 Beilstein:5745751 CAS:51543-40-9 (2R)-2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid chebi_ontology (-)-(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid (2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid (R)-2-fluoro-alpha-methyl(1,1'-biphenyl)-4-acetic acid Flurizan Tarenflurbil CHEBI:38666 (R)-flurbiprofen Any member of the class of biphenyls that is a mono or poly-substituted biphenyl having fluro group as one of the substituents. chebi_ontology fluorobiphenyls CHEBI:38679 fluorobiphenyl Any flavonoid that is a glycoside derivative of anthocyanidin. Anthocyanins are water-souluble plant pigments that generally occur as acidic salts exhibiting bright colours. chebi_ontology anthocyanins CHEBI:38697 anthocyanin A class of lipoproteins of small size (18-25 nm) and low density (1.019-1.063 g/ml) particles with a core composed mainly of cholesterol esters and smaller amounts of triglycerides. The surface monolayer consists mostly of phospholipids, a single copy of apolipoprotein B-100, and free cholesterol molecules. The main function of LDL is to transport cholesterol and cholesterol esters from the liver. Excessive levels are associated with cardiovascular disease. PMID:11082530 PMID:15583011 PMID:15913955 PMID:19349632 PMID:28401639 PMID:28432662 PMID:28792690 PMID:28827781 PMID:28847800 PMID:28859941 PMID:28870972 Wikipedia:Low-density_lipoprotein chebi_ontology LDL beta-lipoproteins low-density lipoproteins CHEBI:39026 low-density lipoprotein A dihydroxy monocarboxylic acid that is a member of the drug class known as statins, used primarily for lowering blood cholesterol and for preventing cardiovascular diseases. 0 C33H35FN2O5 InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1 XUKUURHRXDUEBC-KAYWLYCHSA-N 558.63988 558.25300 CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O CHEBI:2910 CHEBI:39538 Beilstein:8373630 CAS:134523-00-5 DrugBank:DB01076 Drug_Central:257 HMDB:HMDB0005006 KEGG:C06834 KEGG:D07474 LINCS:LSM-5771 PDBeChem:117 PMID:11693468 PMID:15012735 PMID:18720283 Patent:EP409281 Patent:US5273995 Reaxys:8373630 Wikipedia:Atorvastatin (3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-4-phenyl-2-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid Atorvastatin chebi_ontology (R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid 7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID Atorlip atorvastatin atorvastatina atorvastatine atorvastatinum CHEBI:39548 atorvastatin A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. 0 C21H20O6 InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+ VFLDPWHFBUODDF-FCXRPNKRSA-N 368.381 368.12599 C1(=CC(=C(O)C=C1)OC)/C=C/C(CC(/C=C/C2=CC(=C(O)C=C2)OC)=O)=O CAS:458-37-7 HMDB:HMDB0002269 KEGG:C10443 KNApSAcK:C00002731 MetaCyc:CPD-6602 PMID:10923784 PMID:12083767 PMID:12826232 PMID:14561543 PMID:14634121 PMID:15129424 PMID:15659840 PMID:15753945 PMID:15809436 PMID:15842781 PMID:15879598 PMID:16276182 PMID:16292655 PMID:16972983 PMID:17182546 PMID:18815282 PMID:19038979 PMID:19204190 PMID:19234767 PMID:20057137 PMID:21466422 PMID:21642934 PMID:22044005 PMID:22051121 PMID:22118895 PMID:22122768 PMID:22211691 PMID:22318308 PMID:22753715 PMID:23386263 PMID:23574161 PMID:9698073 Patent:DE859145 Patent:KR20130050834 Reaxys:2306965 Wikipedia:Curcumin (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione Curcumin curcumin chebi_ontology C.I. 75300 C.I. Natural Yellow 3 Diferuloylmethane E 100 Kacha haldi Natural yellow 3 Turmeric yellow CHEBI:3962 curcumin A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). 0 C24H36O5 InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1 PCZOHLXUXFIOCF-BXMDZJJMSA-N 404.53964 404.25627 [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)[C@@H](C)CC CHEBI:40299 CHEBI:6544 Beilstein:3631989 CAS:75330-75-5 DrugBank:DB00227 Drug_Central:1612 HMDB:HMDB0014372 KEGG:C07074 KEGG:D00359 KNApSAcK:C00000547 LINCS:LSM-2189 PDBeChem:803 PMID:11375168 PMID:11389707 PMID:11483865 PMID:18642339 PMID:24093797 PMID:7720768 Patent:CN103172602 Patent:WO2013090461 Reaxys:4720754 Wikipedia:Lovastatin (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate LOVASTATIN Lovastatin lovastatin chebi_ontology (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate 2beta,6alpha-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone 6alpha-methylcompactin MK-803 ML-530B Mevacor Mevinolin CHEBI:40303 lovastatin A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3 and 5 by 4-sulfamoylphenyl, trifluoromethyl and p-tolyl groups, respectively. A cyclooxygenase-2 inhibitor, it is used in the treatment of arthritis. 0 C17H14F3N3O2S InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 381.37200 381.07588 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F CHEBI:3520 CHEBI:41418 CAS:169590-42-5 CAS:184007-95-2 DrugBank:DB00482 Drug_Central:568 HMDB:HMDB0005014 KEGG:C07589 KEGG:D00567 LINCS:LSM-2032 PDBeChem:CEL PMID:17983259 PMID:18405470 PMID:19137124 PMID:19203891 PMID:21955617 PMID:22141388 PMID:22419293 PMID:22971036 PMID:23296687 PMID:23506230 PMID:28166217 Reaxys:8280770 Wikipedia:Celecoxib 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide Celecoxib chebi_ontology Celebrex celecoxib celecoxibum p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide CHEBI:41423 celecoxib A benzazepine alkaloid isolated from certain species of daffodils. 0 C17H21NO3 InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1 ASUTZQLVASHGKV-JDFRZJQESA-N 287.35358 287.15214 [H][C@]12C[C@@H](O)C=C[C@]11CCN(C)Cc3ccc(OC)c(O2)c13 CHEBI:42935 CHEBI:5264 Beilstein:93736 CAS:357-70-0 DrugBank:DB00674 Drug_Central:1272 KEGG:C08526 KEGG:D04292 KNApSAcK:C00001570 LINCS:LSM-5604 PDBeChem:GNT PMID:11060814 PMID:11950787 PMID:12177686 PMID:14674789 PMID:15495017 PMID:15537482 PMID:16437436 PMID:19253410 PMID:19782102 PMID:5333582 Reaxys:93736 Wikipedia:Galantamine Galanthamine galanthamine chebi_ontology (-)-GALANTHAMINE Galantamine CHEBI:42944 galanthamine A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. 0 C12H12N2O2S InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2 MQJKPEGWNLWLTK-UHFFFAOYSA-N 248.30100 248.06195 Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1 CHEBI:226356 Beilstein:788055 CAS:80-08-0 DrugBank:DB00250 Drug_Central:782 HMDB:HMDB0014395 KEGG:C07666 KEGG:D00592 LINCS:LSM-5714 PMID:16361748 PMID:18035772 PMID:24232126 PMID:24512442 PMID:28434260 PMID:28699887 PMID:28732451 PMID:29045131 PMID:29192974 PMID:29192999 PMID:29233746 PMID:29280553 Patent:FR829926 Reaxys:788055 Wikipedia:Dapsone 4,4'-sulfonyldianiline DAPSONE Dapsone chebi_ontology 1,1'-sulfonylbis(4-aminobenzene) 4,4'-Sulfonylbisbenzenamine 4,4'-dapsone 4,4'-diaminodiphenyl sulfone 4,4'-sulfonylbisaniline 4-(4-amino-benzenesulfonyl)-phenylamine 4-(4-aminophenylsulfonyl)aniline 4-(4-aminophenylsulfonyl)benzenamine 4-aminophenyl sulfone Bis(p-aminophenyl) sulfone DADPS DDS DIAPHENYLSULFONE Diaphenylsulfone bis(4-aminophenyl)sulfone dapsona dapsone dapsonum p,p'-diaminodiphenyl sulfone p,p-sulphonylbisbenzamine p,p-sulphonylbisbenzenamine p-aminophenyl sulfone CHEBI:4325 dapsone 0 C19H20O5 InChI=1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1 CUKSFECWKQBVED-INIZCTEOSA-N 328.360 328.13107 CC(C)=CC(=O)O[C@H]1Cc2cc3ccc(=O)oc3cc2OC1(C)C CAS:5928-25-6 KEGG:C09258 KNApSAcK:C00002465 Decursin chebi_ontology CHEBI:4353 Decursin 0 C21H31N3O5 InChI=1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1 RLAWWYSOJDYHDC-BZSNNMDCSA-N 405.48790 405.22637 NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O CHEBI:43750 Beilstein:4276619 CAS:76547-98-3 DrugBank:DB00722 Drug_Central:1587 LINCS:LSM-5756 PDBeChem:LPR Wikipedia:Lisinopril N(2)-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline chebi_ontology (S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline [N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE lisinopril anhydrous CHEBI:43755 lisinopril A member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. 0 C21H24F3N3S InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 407.49669 407.16430 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 CHEBI:45949 CHEBI:9709 Beilstein:57272 CAS:117-89-5 DrugBank:DB00831 Drug_Central:2740 Gmelin:2415561 HMDB:HMDB0014969 KEGG:C07168 KEGG:D08636 LINCS:LSM-4010 PDBeChem:TFP PMID:11121417 PMID:14974020 PMID:15722405 PMID:1650428 PMID:19277699 PMID:19747949 PMID:20544963 PMID:7404501 PMID:9730919 Reaxys:57272 Wikipedia:Trifluoperazine 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine Trifluoperazine chebi_ontology 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine trifluoperazina trifluoperazine trifluoperazinum trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine trifluoroperazine trifluperazine CHEBI:45951 trifluoperazine A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease. 0 C13H14N2 InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15) YLJREFDVOIBQDA-UHFFFAOYSA-N 198.26374 198.11570 Nc1c2CCCCc2nc2ccccc12 CHEBI:45978 CHEBI:9389 Beilstein:147610 CAS:321-64-2 DrugBank:DB00382 Drug_Central:2551 KEGG:C01453 KEGG:D08555 LINCS:LSM-5871 PDBeChem:THA PMID:10817586 PMID:24560791 PMID:7866482 Reaxys:147610 Wikipedia:Tacrine 1,2,3,4-tetrahydroacridin-9-amine TACRINE Tacrine chebi_ontology 1,2,3,4-tetrahydro-9-acridinamine 1,2,3,4-tetrahydro-9-aminoacridine 5-amino-6,7,8,9-tetrahydroacridine 9-amino-1,2,3,4-tetrahydroacridine tetrahydroaminacrine CHEBI:45980 tacrine A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug. 0 C19H21NO InChI=1S/C19H21NO/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19/h3-6,8-12H,7,13-14H2,1-2H3 ODQWQRRAPPTVAG-UHFFFAOYSA-N 279.37618 279.16231 [H]C(CCN(C)C)=C1c2ccccc2COc2ccccc12 Beilstein:1348849 CAS:1668-19-5 DrugBank:DB01142 Drug_Central:956 HMDB:HMDB0015273 KEGG:C06971 KEGG:D07875 LINCS:LSM-2803 PMID:15014590 PMID:19357442 Reaxys:1348849 Wikipedia:Doxepin 3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine Doxepin chebi_ontology 3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine CHEBI:4710 doxepin An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. 0 C22H22FN3O2 InChI=1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28) RMEDXOLNCUSCGS-UHFFFAOYSA-N 379.42740 379.16961 Fc1ccc(cc1)C(=O)CCCN1CCC(=CC1)n1c2ccccc2[nH]c1=O CHEBI:252751 Beilstein:579168 CAS:548-73-2 DrugBank:DB00450 Drug_Central:966 KEGG:D00308 LINCS:LSM-4193 Patent:US3161645 Wikipedia:Droperidol 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one chebi_ontology 1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone 1-(1-(4-(p-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone 1-{1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1,3-dihydro-benzoimidazol-2-one 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl}-2,3-dihydro-1H-benzo[d]imidazol-2-one droperidol droperidolum CHEBI:4717 droperidol A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position. 0 C14H11Cl2NO2 InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) DCOPUUMXTXDBNB-UHFFFAOYSA-N 296.150 295.01668 C1(Cl)=CC=CC(=C1NC2=CC=CC=C2CC(=O)O)Cl CHEBI:4507 CHEBI:47380 Beilstein:2146636 CAS:15307-86-5 DrugBank:DB00586 Drug_Central:865 HMDB:HMDB0014724 KEGG:C01690 KEGG:D07816 LINCS:LSM-2160 PDBeChem:DIF PMID:11322639 PMID:1502708 PMID:23777257 PMID:27967303 PMID:7838674 Patent:NL6604752 Patent:US3558690 Reaxys:2146636 VSDB:1933 Wikipedia:Diclofenac 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid Diclofenac {2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid chebi_ontology 2-((2,6-dichlorophenyl)amino)benzeneacetic acid [2-(2,6-dichloroanilino)phenyl]acetic acid diclofenac diclofenac acid diclofenaco diclofenacum diclofenamic acid CHEBI:47381 diclofenac A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom. 0 C19H24N2 InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3 BCGWQEUPMDMJNV-UHFFFAOYSA-N 280.40734 280.19395 CN(C)CCCN1c2ccccc2CCc2ccccc12 CHEBI:47498 CHEBI:5881 Beilstein:256892 CAS:50-49-7 DrugBank:DB00458 Drug_Central:1427 Gmelin:1572523 HMDB:HMDB0001848 KEGG:C07049 KEGG:D08070 LINCS:LSM-2852 PDBeChem:IXX PMID:20825390 Patent:US2554736 Reaxys:256892 Wikipedia:Imipramine 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine Imipramine chebi_ontology 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine Antideprin Imipramin Irmin Melipramine N-(gamma-dimethylaminopropyl)iminodibenzyl imipramine imipraminum imizine CHEBI:47499 imipramine A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias. 0 C19H23ClN2 InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3 GDLIGKIOYRNHDA-UHFFFAOYSA-N 314.85210 314.15498 CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12 CHEBI:3754 CHEBI:47359 Beilstein:1323477 CAS:303-49-1 DrugBank:DB01242 Drug_Central:701 KEGG:C06918 KEGG:D07727 LINCS:LSM-3171 PDBeChem:CXX PMID:12007764 PMID:12084414 PMID:16085036 PMID:17471183 PMID:19747949 PMID:19810911 Patent:CH371799 Patent:US3467650 Reaxys:1323477 Wikipedia:Clomipramine 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine Clomipramine chebi_ontology 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine 3-chloroimipramine G 34586 chlorimipramine monochlorimipramine CHEBI:47780 clomipramine A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group. 0 C18H22N2 InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3 HCYAFALTSJYZDH-UHFFFAOYSA-N 266.38076 266.17830 CNCCCN1c2ccccc2CCc2ccccc12 CHEBI:4448 CHEBI:47393 Beilstein:1432747 CAS:50-47-5 DrugBank:DB01151 Drug_Central:812 HMDB:HMDB0015282 KEGG:C06943 KEGG:D07791 LINCS:LSM-3351 PDBeChem:DSM PMID:11041270 PMID:11287497 PMID:19328214 PMID:20825390 PMID:24399719 Reaxys:1432747 Wikipedia:Desipramine 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine Desipramine chebi_ontology 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE 5-(gamma-methylaminopropyl)iminodibenzyl DMI Desipramin N-(3-methylaminopropyl)iminobibenzyl demethylimipramine desipramina desipramine desipraminum desmethylimipramine monodemethylimipramine norimipramine CHEBI:47781 desipramine A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration). 0 C20H28N2O5 InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1 GBXSMTUPTTWBMN-XIRDDKMYSA-N 376.44670 376.19982 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O CHEBI:116847 Beilstein:3657467 CAS:75847-73-3 DrugBank:DB00584 Drug_Central:1005 HMDB:HMDB0014722 KEGG:C06977 KEGG:D07892 LINCS:LSM-3282 MetaCyc:CPD0-2065 PMID:10669559 PMID:23030053 PMID:23413003 Patent:EP12401 Patent:US4374829 Wikipedia:Enalapril ENALAPRIL Enalapril N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline chebi_ontology (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester analapril enalapril enalaprila enalaprilum CHEBI:4784 enalapril A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position. 0 C19H20N2O2 InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3 VYMDGNCVAMGZFE-UHFFFAOYSA-N 308.37430 308.15248 CCCCC1C(=O)N(N(C1=O)c1ccccc1)c1ccccc1 CHEBI:44635 CHEBI:8091 Beilstein:290080 CAS:50-33-9 DrugBank:DB00812 Drug_Central:2145 HMDB:HMDB0014950 KEGG:C07440 KEGG:D00510 LINCS:LSM-2219 PDBeChem:P1Z PMID:11264893 PMID:12692637 PMID:13010905 PMID:13048452 PMID:13747451 PMID:19614844 PMID:20176071 PMID:21668837 PMID:22082440 PMID:22180948 PMID:22245664 PMID:23369749 PMID:23525812 PMID:25287371 PMID:26090772 PMID:26808199 PMID:3425858 PMID:7655439 Reaxys:290080 VSDB:1775 Wikipedia:Phenylbutazone 4-butyl-1,2-diphenylpyrazolidine-3,5-dione Phenylbutazone chebi_ontology 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione Phenbutazone Phenylbutazon fenilbutazona phenylbutazone phenylbutazonum CHEBI:48574 phenylbutazone Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own. agonist chebi_ontology agonista agoniste agonists CHEBI:48705 agonist Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. antagonist chebi_ontology antagonista antagoniste antagonists CHEBI:48706 antagonist CAS:185243-69-0 DrugBank:DB00005 KEGG:C07897 KEGG:D00742 Patent:US5605690 Patent:WO946476 Etanercept chebi_ontology CHEBI:4875 etanercept A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active. 0 C17H21NO3 InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20) NNYBQONXHNTVIJ-UHFFFAOYSA-N 287.35350 287.15214 CCc1cccc2c3CCOC(CC)(CC(O)=O)c3[nH]c12 CHEBI:126431 CAS:41340-25-4 DrugBank:DB00749 Drug_Central:1103 HMDB:HMDB0014887 KEGG:D00315 LINCS:LSM-1781 PMID:15369391 PMID:2527995 PMID:28166217 PMID:2970548 Patent:DE2301525 Patent:US3939178 Wikipedia:Etodolac (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid ETODOLAC chebi_ontology (+-)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid (1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid ETODOLIC ACID etodolac etodolaco etodolacum CHEBI:4909 etodolac +1 Cu InChI=1S/Cu/q+1 VMQMZMRVKUZKQL-UHFFFAOYSA-N 63.54600 62.92905 [Cu+] CHEBI:23379 CHEBI:49551 CAS:17493-86-6 Gmelin:15189 PDBeChem:CU1 copper(1+) copper(1+) ion copper(I) cation chebi_ontology COPPER (I) ION Cu(+) copper cation copper(1+) ion copper(I) cation cuprous ion CHEBI:49552 copper(1+) A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. 0 C19H16ClNO4 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 357.78800 357.07679 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 CHEBI:49660 CHEBI:5918 Beilstein:497341 CAS:53-86-1 DrugBank:DB00328 Drug_Central:1440 Gmelin:1446006 HMDB:HMDB0014473 KEGG:C01926 KEGG:D00141 KNApSAcK:C00030512 LINCS:LSM-3275 MetaCyc:CPD-10545 PDBeChem:IMN PMID:22931205 PMID:23992308 PMID:28166217 PMID:5952296 PMID:6039425 Patent:BE379378 Patent:US3161654 Reaxys:497341 Wikipedia:Indometacin [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid chebi_ontology 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid Aconip Indocin Indomethacin indometacin indometacina indometacine indometacinum {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid CHEBI:49662 indometacin +1 Li InChI=1S/Li/q+1 HBBGRARXTFLTSG-UHFFFAOYSA-N 6.94100 7.01545 [Li+] CHEBI:30143 CHEBI:49711 CAS:17341-24-1 DrugBank:DB01356 Gmelin:15205 PDBeChem:LI lithium(1+) lithium(1+) ion lithium(I) cation chebi_ontology LITHIUM ION Li(+) Lithium, ion (Li1+) lithium cation lithium, ion CHEBI:49713 lithium(1+) A monocarboxylic acid that is propanoic acid in which one of the hydrogens at position 2 is substituted by a 3-phenoxyphenyl group. A non-steroidal anti-inflammatory drug, the dihydrate form of the calcium salt is used for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding. 0 C15H14O3 InChI=1S/C15H14O3/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13/h2-11H,1H3,(H,16,17) RDJGLLICXDHJDY-UHFFFAOYSA-N 242.26990 242.09429 CC(C(O)=O)c1cccc(Oc2ccccc2)c1 CHEBI:355534 CAS:31879-05-7 DrugBank:DB00573 Drug_Central:1154 KEGG:C06997 KEGG:D02350 PMID:21328296 PMID:21342694 PMID:25554116 PMID:28166217 PMID:30168706 PMID:4616811 Patent:US3600437 Reaxys:2118687 Wikipedia:_Fenoprofen 2-(3-phenoxyphenyl)propanoic acid FENOPROFEN Fenoprofen chebi_ontology (+-)-2-(3-phenoxyphenyl)propionic acid (+-)-m-phenoxyhydratropic acid 2-(3-phenoxyphenyl)propionic acid 2-(m-phenoxyphenyl)propionic acid alpha-(m-phenoxyphenyl)propionic acid alpha-methyl-3-phenoxybenzeneacetic acid fenoprofen fenoprofene fenoprofeno fenoprofenum CHEBI:5004 fenoprofen A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens. Wikipedia:Estrogen chebi_ontology Estrogene Oestrogen Oestrogene estrogene estrogenes estrogenes Hormon estrogeno estrogenos estrogens oestrogen oestrogene oestrogenes oestrogens CHEBI:50114 estrogen 0 C18H19N3O3S InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23) YASAKCUCGLMORW-UHFFFAOYSA-N 357.42700 357.11471 CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 Beilstein:7082202 CAS:122320-73-4 DrugBank:DB00412 Drug_Central:2405 LINCS:LSM-1949 PMID:17259370 PMID:30225267 PMID:31936729 PMID:32234642 PMID:33650786 PMID:33746608 Patent:EP306228 Patent:US5002953 Wikipedia:Rosiglitazone 5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione chebi_ontology 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione BRL-49653 rosiglitazona rosiglitazone rosiglitazonum CHEBI:50122 rosiglitazone A 3-hydroxy-5alpha-pregnan-20-one in which the hydroxy group at position 3 has alpha-configuration. It is a metabolite of the sex hormone progesterone and used for the treatment of postpartum depression in women. 0 C21H34O2 InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15+,16-,17+,18-,19-,20-,21+/m0/s1 AURFZBICLPNKBZ-SYBPFIFISA-N 318.49346 318.25588 [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@]([H])(C(C)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2 CHEBI:32924 CHEBI:34347 Beilstein:3211363 CAS:516-54-1 DrugBank:DB11859 FooDB:FDB022630 HMDB:HMDB0001449 KEGG:C13712 KEGG:D11149 LINCS:LSM-19998 LIPID_MAPS_instance:LMST02030130 PMID:10625505 PMID:11739473 PMID:19290593 PMID:28370307 PMID:28619476 PMID:28666923 PMID:28779545 PMID:29453777 PMID:29636114 PMID:30177236 PMID:30362283 PMID:30481569 PMID:30701996 PMID:9501247 Wikipedia:Allopregnanolone 3alpha-hydroxy-5alpha-pregnan-20-one chebi_ontology (3alpha,5alpha)-3-hydroxypregnan-20-one 3alpha,5alpha-THP 3alpha,5alpha-tetrahydroprogesterone 3alpha-OH DHP 3alpha-hydroxy-5alpha-dihydroprogesterone 3alpha-hydroxy-5alpha-pregnan-20-one 5alpha-pregnan-3alpha-ol-20-one SAGE-547 SGE-102 Zulresso allopregnan-3alpha-ol-20-one allopregnanolone allotetrahydroprogesterone brexanolona brexanolone brexanolonum CHEBI:50169 brexanolone 0 C13H17N InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3 MEZLKOACVSPNER-UHFFFAOYSA-N 187.28082 187.13610 CC(Cc1ccccc1)N(C)CC#C Beilstein:2092580 DrugBank:DB01037 N-methyl-N-(1-methyl-2-phenylethyl)prop-2-yn-1-amine chebi_ontology selegilina selegiline selegilinum CHEBI:50217 selegiline A gamma-lactone that consists of a 2-furanone skeleton and its substituted derivatives. 0 C4H4O2 84.074 84.02113 CHEBI:22960 CHEBI:38121 Wikipedia:Butenolide furan-2-one chebi_ontology 2-furanone butenolides CHEBI:50523 butenolide A biphenyl compound comprising two tyrosine residues linked at carbon-3 of their benzene rings. 0 C18H20N2O6 InChI=1S/C18H20N2O6/c19-13(17(23)24)7-9-1-3-15(21)11(5-9)12-6-10(2-4-16(12)22)8-14(20)18(25)26/h1-6,13-14,21-22H,7-8,19-20H2,(H,23,24)(H,25,26) OQALFHMKVSJFRR-UHFFFAOYSA-N 360.36128 360.13214 NC(Cc1ccc(O)c(c1)-c1cc(CC(N)C(O)=O)ccc1O)C(O)=O Beilstein:2228674 CAS:980-21-2 PMID:15589368 PMID:17019703 PMID:24351276 PMID:24573970 3,3'-(6,6'-dihydroxybiphenyl-3,3'-diyl)bis(2-aminopropanoic acid) chebi_ontology 3,3'-dityrosine alpha,alpha'-diamino-6,6'-dihydroxy-(1,1'-biphenyl)-3,3'-dipropanoic acid bityrosine o,o-dityrosine CHEBI:50607 dityrosine The D isomer of N-acetylglucosamine. 0 C8H15NO6 InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1 OVRNDRQMDRJTHS-RTRLPJTCSA-N 221.20780 221.08994 CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O Beilstein:1913592 CAS:7512-17-6 DrugBank:DB00141 GlyGen:G64581RP GlyTouCan:G64581RP KEGG:C00140 PDBeChem:NAG PMID:11950472 PMID:21487204 PMID:6174502 PMID:7688662 2-acetamido-2-deoxy-D-glucopyranose N-Acetyl-D-glucosamine N-acetyl-D-glucosamine chebi_ontology 2-Acetamido-2-deoxy-D-glucose GlcNAc N-Acetylchitosamine WURCS=2.0/1,1,0/[a2122h-1x_1-5_2*NCC/3=O]/1/ CHEBI:506227 N-acetyl-D-glucosamine 0 C18H18ClN3O InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 327.80784 327.11384 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 CHEBI:50839 CHEBI:6548 Beilstein:626753 CAS:1977-10-2 DrugBank:DB00408 Drug_Central:1613 KEGG:C07104 KEGG:D02340 LINCS:LSM-2881 Patent:NL6406089 Patent:US3412193 Patent:US3546226 Wikipedia:Loxapine 2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine Loxapine chebi_ontology 2-chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine Cloxazepine loxapina loxapine loxapinum oxilapine CHEBI:50841 loxapine Any molecular entity that contains carbon. CHEBI:25700 CHEBI:33244 chebi_ontology organic compounds organic entity organic molecular entities CHEBI:50860 organic molecular entity An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose. 0 C15H14FN3O3 InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3 OFBIFZUFASYYRE-UHFFFAOYSA-N 303.289 303.10192 C1=NC(=C2N1C=3C(C(N(C2)C)=O)=CC(=CC3)F)C(OCC)=O Beilstein:4763661 CAS:78755-81-4 DrugBank:DB01205 Drug_Central:1195 HMDB:HMDB0015336 KEGG:C07825 KEGG:D00697 LINCS:LSM-4228 PMID:11881583 PMID:23126253 PMID:23431889 PMID:24563235 PMID:26324010 PMID:26469689 Reaxys:4763661 Wikipedia:Flumazenil ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate chebi_ontology Anexate Lanexat flumazenil flumazenilo flumazenilum CHEBI:5103 flumazenil 0 C17H22N4O InChI=1S/C17H22N4O/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21/h2-6,13H,7-12H2,1H3,(H,18,20) LDMWSLGGVTVJPG-UHFFFAOYSA-N 298.38294 298.17936 Cc1cc(nnc1NCCN1CCOCC1)-c1ccccc1 Beilstein:1219740 CAS:25905-77-5 DrugBank:DB00805 Drug_Central:1812 KEGG:D05039 LINCS:LSM-2037 Patent:DE2229215 Patent:US4169158 4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine chebi_ontology 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine 4-Methyl-3-(2-morpholinoethylamino)-6-phenylpyridazin N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine minaprina minaprine minaprinum CHEBI:51038 minaprine A role played by the molecular entity or part thereof within a chemical context. chebi_ontology CHEBI:51086 chemical role CHEBI:25556 CHEBI:7594 KEGG:C06061 chebi_ontology Nitrogenous compounds nitrogen compounds nitrogen molecular entities CHEBI:51143 nitrogen molecular entity A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder. 0 C17H18F3NO 309.32610 309.13405 Beilstein:39914106 CAS:54910-89-3 DrugBank:DB00472 HMDB:HMDB0014615 KEGG:D00326 PMID:19144769 PMID:22903652 PMID:22923967 PMID:23885544 PMID:24184049 PMID:24399719 PMID:24464553 PMID:24997906 PMID:25448156 PMID:25639887 PMID:25671301 PMID:8694321 Patent:DE2500110 Patent:US4314081 Reaxys:3991406 Wikipedia:Fluoxetine rac-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine chebi_ontology (+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine (+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine Prozac fluoxetina fluoxetine fluoxetinum CHEBI:5118 fluoxetine A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. 0 C22H26F3N3OS InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 437.52200 437.17487 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 Beilstein:1189506 Beilstein:61643 CAS:69-23-8 DrugBank:DB00623 Drug_Central:1212 Gmelin:1231182 HMDB:HMDB0014761 KEGG:C07010 KEGG:D07977 LINCS:LSM-3226 PMID:13950763 PMID:16117689 PMID:1650428 PMID:16839522 PMID:25595294 PMID:5128930 Patent:GB829246 Patent:GB833474 Patent:US3058979 Patent:US3194733 Reaxys:61643 Wikipedia:Fluphenazine 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol Fluphenazine chebi_ontology 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine 10-(3'-(4''-(beta-hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol 2-(trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol 4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol Fluorfenazine Fluorophenazine Fluorphenazine Triflumethazine flufenazina fluphenazine fluphenazinum CHEBI:5123 fluphenazine A compound of general formula RC(=O)SR'. Compare with thionoester, RC(=S)OR'. 0 COSR2 60.07500 59.96699 [*]C(=O)S[*] chebi_ontology thio ester thioesters thiol ester CHEBI:51277 thioester A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia. 0 C21H23ClFN3O InChI=1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3 SAADBVWGJQAEFS-UHFFFAOYSA-N 387.880 387.15137 C(CN(CC)CC)N1C=2C(C(=NCC1=O)C3=CC=CC=C3F)=CC(=CC2)Cl CAS:17617-23-1 DrugBank:DB00690 Drug_Central:1218 HMDB:HMDB0014828 KEGG:D00329 PDBeChem:FL7 PMID:16501350 PMID:20002022 PMID:23035248 PMID:2863335 Wikipedia:Flurazepam 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one chebi_ontology Insumin Ro 5-6901 flurazepam flurazepamum CHEBI:5128 flurazepam An oxime O-ether that is benzene substituted by a (1E)-N-(2-aminoethoxy)-5-methoxypentanimidoyl group at position 1 and a trifluoromethyl group at position 4. It is a selective serotonin reuptake inhibitor that is used for the treatment of obsessive-compulsive disorder. 0 C15H21F3N2O2 InChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3/b20-14+ CJOFXWAVKWHTFT-XSFVSMFZSA-N 318.340 318.15551 COCCCC\C(=N/OCCN)C1=CC=C(C=C1)C(F)(F)F Beilstein:5583954 CAS:54739-18-3 Chemspider:4481878 DrugBank:DB00176 Drug_Central:1230 HMDB:HMDB0014322 KEGG:C07571 KEGG:D07984 MetaCyc:CPD-20520 PDBeChem:FVX PMID:10456487 PMID:11825104 PMID:12107854 PMID:15686112 PMID:16316311 PMID:18976545 PMID:20025739 PMID:20573265 PMID:22859721 PMID:24121440 PMID:29379174 PMID:30690950 PMID:30734885 PMID:31807102 PMID:31807753 PMID:32618683 PMID:32672818 PMID:33180097 PMID:33392622 PMID:7988100 PMID:9164424 Patent:NL7503310 Patent:US4085225 Wikipedia:Fluvoxamine (1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one O-(2-aminoethyl)oxime Fluvoxamine chebi_ontology 2-{[(E)-{5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino]oxy}ethan-1-amine O-(2-aminoethyl)-N-{(1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}hydroxylamine fluvoxamina fluvoxamine fluvoxaminum CHEBI:5138 fluvoxamine A phosphinate ester-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. It is used for the treatment of hypertension and heart failure. A pro-drug, it is hydrolysed in vivo to the corresponding phosphininc acid, fosinoprilat, which is the active metabolite. 0 C30H46NO7P InChI=1S/C30H46NO7P/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35)/t25-,26+,30?,39?/m1/s1 BIDNLKIUORFRQP-FKDWWROVSA-N 563.66250 563.30119 [H][C@]1(C[C@H](N(C1)C(=O)CP(=O)(CCCCc1ccccc1)OC(OC(=O)CC)C(C)C)C(O)=O)C1CCCCC1 CHEBI:159901 CHEBI:288733 Beilstein:8176492 CAS:98048-97-6 DrugBank:DB00492 KEGG:C07016 KEGG:D07992 LINCS:LSM-6485 PMID:11937741 PMID:18209565 PMID:22729889 PMID:8285178 PMID:9195116 Patent:CN101367839 Patent:EP2264039 Patent:US2010297711 Patent:US4337201 (4S)-4-cyclohexyl-1-({[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)-L-proline Fosinopril chebi_ontology (2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid (2S,4S)-4-cyclohexyl-1-{2-[(2-methyl-1-propionyloxy-propoxy)-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid (S)-4-Cyclohexyl-1-{2-[(2-methyl-1-propionyloxy-propoxy)-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid fosinopril CHEBI:5163 fosinopril A biological role played by the molecular entity or part thereof within a biochemical context. chebi_ontology CHEBI:52206 biochemical role A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties. chebi_ontology CHEBI:52210 pharmacological role chebi_ontology CHEBI:52211 physiological role Any substance introduced into a living organism with therapeutic or diagnostic purpose. CHEBI:33293 CHEBI:33294 chebi_ontology farmaco medicament pharmaceuticals CHEBI:52217 pharmaceutical A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. 0 C24H29NO3 InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3 ADEBPBSSDYVVLD-UHFFFAOYSA-N 379.500 379.21474 C1(=C(C=C2C(=C1)CC(C2=O)(CC3CCN(CC3)CC4=CC=CC=C4)[H])OC)OC Beilstein:7081955 CAS:120014-06-4 DrugBank:DB00843 Drug_Central:946 KEGG:D07869 LINCS:LSM-1598 Reaxys:7081955 Wikipedia:Donepezil chebi_ontology donepezil donepezilo donepezilum CHEBI:53289 donepezil 0 C6H13NO5 179.171 179.07937 DrugBank:DB01296 KEGG:C01811 2-amino-2-deoxyglucose Glucosamine glucosamine chebi_ontology 2-Amino-2-deoxy-glucose GlcN Glucosamin Glukosamin CHEBI:5417 glucosamine An aldotriose comprising propanal having hydroxy groups at the 2- and 3-positions. It plays role in the formation of advanced glycation end-products (AGEs), a deleterious accompaniment to ageing. 0 C3H6O3 InChI=1S/C3H6O3/c4-1-3(6)2-5/h1,3,5-6H,2H2 MNQZXJOMYWMBOU-UHFFFAOYSA-N 90.07794 90.03169 [H]C(=O)C(O)CO CHEBI:24343 CHEBI:387614 Beilstein:635844 CAS:367-47-5 CAS:56-82-6 DrugBank:DB02536 Gmelin:164389 HMDB:HMDB0001051 KEGG:C02154 KNApSAcK:C00007413 MetaCyc:CPD0-1551 PMID:18087047 PMID:18256486 PMID:18791692 PMID:20371493 PMID:21707087 PMID:23543734 PMID:9506998 Reaxys:635844 Wikipedia:Glyceraldehyde 2,3-dihydroxypropanal Glyceraldehyde glyceraldehyde chebi_ontology (+-)-glyceraldehyde 2,3-Dihydroxypropanal 2,3-Dihydroxypropionaldehyde Aldotriose DL-glyceraldehyde Glyceraldehyd Glycerinaldehyd Glycerose Glyzerinaldehyd alpha,beta-dihydroxypropionaldehyde gliceraldehido glyceric aldehyde glycerinaldehyde glycerinformal glycerose CHEBI:5445 glyceraldehyde A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety. 0 C21H23ClFNO2 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 375.86400 375.14013 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Beilstein:331267 CAS:52-86-8 DrugBank:DB00502 Drug_Central:1353 KEGG:C01814 KEGG:D00136 LINCS:LSM-3512 PMID:10628896 PMID:11304647 PMID:25007358 PMID:6725621 PMID:7602118 Patent:BE577977 Patent:GB895309 Patent:US3438991 Reaxys:331267 Wikipedia:Haloperidol 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one chebi_ontology 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine 4'-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone 4'-fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone 4-(4-(para-chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one Haldol gamma-(4-(p-chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone haloperidol haloperidolum CHEBI:5613 haloperidol A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form. 0 C3H4O2 InChI=1S/C3H4O2/c4-2-1-3-5/h2-3H,1H2 WSMYVTOQOOLQHP-UHFFFAOYSA-N 72.06270 72.02113 O=CCC=O CHEBI:43895 Beilstein:1209262 CAS:542-78-9 DrugBank:DB03057 Gmelin:362229 KEGG:C19440 PDBeChem:MDD PMID:15583011 PMID:17548130 PMID:23900424 PMID:24168430 PMID:28600633 PMID:28600933 PMID:28783520 PMID:29348025 Reaxys:1209262 malonaldehyde propanedial chebi_ontology 1,3-Propanedial 1,3-Propanedialdehyde 1,3-Propanedione MDA MDD Malondialdehyde Malonic aldehyde Malonic dialdehyde Malonodialdehyde Malonyldialdehyde CHEBI:566274 malonaldehyde A cyclic compound having as ring members atoms of at least two different elements. Heterocyclic compound chebi_ontology compuesto heterociclico compuestos heterociclicos heterocycle heterocyclic compounds CHEBI:5686 heterocyclic compound An O-acyl-L-carnitine where the acyl group specified is acetyl. It facilitates movement of acetyl-CoA into the matrices of mammalian mitochondria during the oxidation of fatty acids. 0 C9H17NO4 InChI=1S/C9H17NO4/c1-7(11)14-8(5-9(12)13)6-10(2,3)4/h8H,5-6H2,1-4H3/t8-/m1/s1 RDHQFKQIGNGIED-MRVPVSSYSA-N 203.23560 203.11576 CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C Beilstein:3667658 CAS:3040-38-8 Drug_Central:64 HMDB:HMDB0000201 KEGG:C02571 MetaCyc:O-ACETYLCARNITINE PMID:22770225 Reaxys:3667658 Wikipedia:Acetyl-L-carnitine (3R)-3-(acetyloxy)-4-(trimethylazaniumyl)butanoate chebi_ontology (-)-Acetylcarnitine (R)-Acetylcarnitine Acetyl-L-(-)-carnitine Acetyl-L-carnitine L-Acetylcarnitine L-Carnitine acetyl ester L-O-Acetylcarnitine O-acetyl-(R)-carnitine R-Acetylcarnitine CHEBI:57589 O-acetyl-L-carnitine The conjugate base of 3-mercaptopyruvic acid. -1 C3H3O3S InChI=1S/C3H4O3S/c4-2(1-7)3(5)6/h7H,1H2,(H,5,6)/p-1 OJOLFAIGOXZBCI-UHFFFAOYSA-M 119.11900 118.98084 [O-]C(=O)C(=O)CS Beilstein:3933339 2-oxo-3-sulfanylpropanoate chebi_ontology 2-oxo-3-sulfanylpropanoate CHEBI:57678 3-mercaptopyruvate A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group. 0 C13H18O2 InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 206.28082 206.13068 CC(C)Cc1ccc(cc1)C(C)C(O)=O Beilstein:2049713 CAS:15687-27-1 DrugBank:DB01050 Drug_Central:1407 HMDB:HMDB0001925 KEGG:C01588 KEGG:D00126 LINCS:LSM-1354 PMID:11433218 PMID:12723739 PMID:14562167 PMID:15506544 PMID:16176022 PMID:18335846 PMID:18697608 PMID:21368281 PMID:24168233 PMID:25708941 PMID:25915907 PMID:29756342 Patent:GB971700 Patent:US3228831 Patent:US3385886 Patent:US5215755 Patent:US6727286 Reaxys:2049713 Wikipedia:Ibuprofen 2-[4-(2-methylpropyl)phenyl]propanoic acid Ibuprofen chebi_ontology (+-)-2-(p-isobutylphenyl)propionic acid (+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid (+-)-ibuprofen (+-)-p-isobutylhydratropic acid (4-isobutylphenyl)-alpha-methylacetic acid (RS)-ibuprofen 2-(4-isobutylphenyl)propanoic acid 4-isobutylhydratropic acid Adran Advil Amibufen Anco Anflagen Apsifen Bluton Brufen Brufort Buburone Butylenin Dolgin Dolgirid Dolgit Dolo-Dolgit Ebufac Epobron Femadon Haltran Ibu-Attritin Ibumetin Ibuprocin Ibutid Inabrin Inoven Lamidon Lebrufen Liptan Medipren Motrin Mynosedin Nobfen Nobgen Nuprin Nurofen Pediaprofen Roidenin Rufen Seclodin Suspren Tabalon Trendar Urem alpha-(4-isobutylphenyl)propionic acid alpha-(p-isobutylphenyl)propionic acid CHEBI:5855 ibuprofen A phenothiazine derivative in which 10H-phenothiazinecarries a 3-(4-methylpiperazin-1-yl)propyl substituent at the N-10 position. 0 C20H25N3S InChI=1S/C20H25N3S/c1-21-13-15-22(16-14-21)11-6-12-23-17-7-2-4-9-19(17)24-20-10-5-3-8-18(20)23/h2-5,7-10H,6,11-16H2,1H3 WEYVCQFUGFRXOM-UHFFFAOYSA-N 339.49800 339.17692 CN1CCN(CCCN2c3ccccc3Sc3ccccc23)CC1 Beilstein:39009 CAS:84-97-9 Drug_Central:2100 Gmelin:298041 KEGG:C16903 PMID:1650428 PMID:19904008 PMID:23479940 PMID:24425538 Patent:GB780193 Reaxys:39009 Wikipedia:Perazine 10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine chebi_ontology 10-(3-(4-Methyl-1-piperazinyl)propyl)-10H-phenothiazine N-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazine N-Methyl-piperazinyl-N'-propyl-phenothiazin N-Methyl-piperazinylpropyl-phenothiazine Pernazine CHEBI:59118 perazine A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types. chebi_ontology Chemische Substanz CHEBI:59999 chemical substance A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind. chebi_ontology Mischung CHEBI:60004 mixture A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.. Wikipedia:Polymer Polymer chebi_ontology Kunststoff CHEBI:60027 polymer A derivative of phosphatidylinositol in which the inositol ring is phosphorylated at three unspecified positions. chebi_ontology phosphatidylinositol trisphosphates CHEBI:60169 phosphatidylinositol trisphosphate Insoluble fibrous protein aggregates exhibiting beta sheet structure. chebi_ontology CHEBI:60425 amyloid fibril Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. CHEBI:60797 chebi_ontology N-methyl-D-aspartate receptor antagonist N-methyl-D-aspartate receptor antagonists NMDA receptor antagonists NMDAR antagonist NMDAR antagonists CHEBI:60643 NMDA receptor antagonist A racemate is an equimolar mixture of a pair of enantiomers. chebi_ontology melange racemique racemates racemic mixture CHEBI:60911 racemate A nucleoside bisphosphate that has a purine nucleobase. chebi_ontology purine nucleoside bisphosphates CHEBI:61078 purine nucleoside bisphosphate A nucleoside bisphosphate where sugar of the nucleoside is ribose. chebi_ontology ribonucleoside bisphosphates CHEBI:61079 ribonucleoside bisphosphate Any compound that has a nucleobase as a part. chebi_ontology nucleobase-containing compound nucleobase-containing compounds nucleobase-containing molecular entities CHEBI:61120 nucleobase-containing molecular entity An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2. 0 C16H14O3 InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19) DKYWVDODHFEZIM-UHFFFAOYSA-N 254.28056 254.09429 CC(C(O)=O)c1cccc(c1)C(=O)c1ccccc1 CAS:22071-15-4 DrugBank:DB01009 Drug_Central:1528 HMDB:HMDB0015144 KEGG:C01716 KEGG:D00132 LINCS:LSM-1955 PMID:11452775 PMID:12772856 PMID:18969772 Reaxys:2216071 Wikipedia:Ketoprofen 2-(3-benzoylphenyl)propanoic acid Ketoprofen chebi_ontology 2-(3-Benzoylphenyl)propionic acid 3-Benzoyl-alpha-methylbenzeneacetic acid 3-Benzoylhydratropic acid L'Acide (benzoyl-3-phenyl)-2-propionique Orudis (TN) m-Benzoylhydratropic acid CHEBI:6128 ketoprofen A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure. 0 C15H13NO3 InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19) OZWKMVRBQXNZKK-UHFFFAOYSA-N 255.269 255.08954 N12C(C(C(=O)O)CC1)=CC=C2C(=O)C3=CC=CC=C3 CAS:74103-06-3 DrugBank:DB00465 HMDB:HMDB0014608 KEGG:C07062 KEGG:D08104 PMID:10027870 PMID:10223774 PMID:10593468 PMID:17456651 PMID:19281996 PMID:22191998 PMID:23088994 PMID:23126437 PMID:23179562 PMID:23298250 PMID:23447046 PMID:23473380 PMID:23562034 PMID:23653032 PMID:23702435 PMID:24022643 PMID:24112670 PMID:28166217 PMID:9549656 Patent:BE856681 Patent:US4089969 Patent:US4347186 Reaxys:413572 Wikipedia:Ketorolac rac-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid chebi_ontology (+-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid (+-)-ketorolac ketorolac ketorolaco ketorolacum rac-ketorolac CHEBI:6129 ketorolac A nucleotide having adenine as the base. chebi_ontology adenine nucleotide CHEBI:61293 adenyl nucleotide A purine riboncleotide where adenine is the purine. chebi_ontology adenine ribonucleotide CHEBI:61296 adenyl ribonucleotide Any organic molecular entity derived from a fatty acid. chebi_ontology FA derivative FA derivatives fatty acid derivatives CHEBI:61697 fatty acid derivative A fatty-acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any hydroxy fatty acid. chebi_ontology hydroxy FA-CoA hydroxy-FA-coenzyme A hydroxy-fatty acyl-CoAs hydroxy-fatty acyl-coenzyme A CHEBI:61902 hydroxy fatty acyl-CoA An enzyme inhibitor that inhibits the action of nitric oxide synthase, EC 1.14.13.39. chebi_ontology EC 1.14.13.39 inhibitor EC 1.14.13.39 inhibitors NADPH-diaphorase inhibitor NADPH-diaphorase inhibitors NO synthase inhibitor NO synthase inhibitors endothelium-derived relaxation factor-forming enzyme inhibitor endothelium-derived relaxation factor-forming enzyme inhibitors endothelium-derived relaxing factor synthase inhibitor endothelium-derived relaxing factor synthase inhibitors nitric oxide synthase inhibitors nitric oxide synthetase inhibitor nitric oxide synthetase inhibitors nitric-oxide synthetase inhibitor nitric-oxide synthetase inhibitors CHEBI:61908 nitric oxide synthase inhibitor An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any hydroxycarboxylic acid. chebi_ontology hydroxyacyl-CoAs hydroxyacyl-coenzyme A CHEBI:62618 hydroxyacyl-CoA Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds. chebi_ontology carbohydrate derivatives derivatised carbohydrate derivatised carbohydrates derivatized carbohydrate derivatized carbohydrates CHEBI:63299 carbohydrate derivative A carbohydrate derivative that is formally obtained from a monosaccharide. chebi_ontology monosaccharide derivatives CHEBI:63367 monosaccharide derivative A monosaccharide derivative that is formally obtained from a pentose. chebi_ontology pentose derivatives CHEBI:63409 pentose derivative A carboxylic ester resulting from the formal condensation of (S)-2-methylbutyric acid with the hydroxy group adjacent to the ring junction of (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid. Derived from microbial transformation of mevastatin, pravastatin is a reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA). The sodium salt is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin. 0 C23H36O7 InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1 TUZYXOIXSAXUGO-PZAWKZKUSA-N 424.52770 424.24610 [H][C@]12[C@H](C[C@H](O)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC(O)=O)OC(=O)[C@@H](C)CC CHEBI:8360 CAS:81093-37-0 DrugBank:DB00175 Drug_Central:2239 HMDB:HMDB0005022 KEGG:C01844 KEGG:D08410 KNApSAcK:C00000565 LINCS:LSM-3347 PMID:21749370 PMID:21851379 PMID:25264019 Reaxys:4825538 Wikipedia:Pravastatin (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid chebi_ontology (+)-(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoic acid pravastatin pravastatin acid pravastatina pravastatine pravastatinum CHEBI:63618 pravastatin An indane that consists of 1-aminoindane bearing an N-propargyl substituent. A selective, irreversible monoamine oxidase-B inhibitor. 0 C12H13N InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1 RUOKEQAAGRXIBM-GFCCVEGCSA-N 171.23830 171.10480 C#CCN[C@@H]1CCc2ccccc12 CAS:136236-51-6 DrugBank:DB01367 KEGG:D08469 PMID:20577110 PMID:21482191 PMID:21500280 PMID:21628600 PMID:21671840 PMID:21819487 PMID:21864207 PMID:21878836 PMID:21895884 PMID:21946113 PMID:21953831 PMID:21971006 PMID:21971007 PMID:22045282 PMID:22065207 Reaxys:9194207 Wikipedia:Rasagiline (1R)-N-(prop-2-yn-1-yl)indan-1-amine chebi_ontology (1R)-N-propargylindan-1-amine (R)-N-2-Propynyl-1-indanamine (R)-indan-1-yl-prop-2-ynyl-amine RAS rasagiline CHEBI:63620 rasagiline A member of the class of isoxazoles that is isoxazole which is substituted at positions 3, 4 and 5 by phenyl, p-sulfamoylphenyl and methyl groups, respectively. A selective cyclooxygenase 2-inhibitor, it used as a nonsteroidal anti-inflammatory drug (NSAID) for the treatment of arthritis from 2001 until 2005, when it was withdrawn following concerns of an associated increased risk of heart attack and stroke. 0 C16H14N2O3S InChI=1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20) LNPDTQAFDNKSHK-UHFFFAOYSA-N 314.35900 314.07251 Cc1onc(-c2ccccc2)c1-c1ccc(cc1)S(N)(=O)=O CHEBI:41662 CAS:181695-72-7 DrugBank:DB00580 Drug_Central:2799 HMDB:HMDB0005033 KEGG:D02709 LINCS:LSM-5305 PDBeChem:COX PMID:20467258 PMID:20717044 PMID:21073910 PMID:21720517 PMID:21769548 Reaxys:8563786 Wikipedia:Valdecoxib 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide chebi_ontology 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide Bextra p-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide valdecoxib valdecoxibum CHEBI:63634 valdecoxib A bioactive polypeptide of 39 amino acid residues isolated from the saliva of the Gila monster (Heloderma suspectum). High-affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM); potently induces cAMP formation without stimulating amylase release in pancreatic acini; potentiates glucose-induced insulin secretion in isolated rat islets; protects against glutamate-induced neurotoxicity. A synthetic version is called exenatide. 0 C184H282N50O60S InChI=1S/C184H282N50O60S/c1-16-94(10)147(178(289)213-114(52-58-144(257)258)163(274)218-121(73-101-77-195-105-39-24-23-38-103(101)105)168(279)215-116(68-90(2)3)165(276)205-107(41-26-28-61-186)158(269)219-122(75-134(189)243)154(265)198-79-135(244)196-83-139(248)231-63-30-43-129(231)175(286)225-127(87-238)174(285)223-125(85-236)155(266)200-80-136(245)202-96(12)181(292)233-65-32-45-131(233)183(294)234-66-33-46-132(234)182(293)232-64-31-44-130(232)176(287)222-124(84-235)150(190)261)229-170(281)119(71-99-34-19-17-20-35-99)217-166(277)117(69-91(4)5)214-159(270)108(42-29-62-194-184(191)192)212-177(288)146(93(8)9)228-151(262)95(11)203-156(267)111(49-55-141(251)252)208-161(272)112(50-56-142(253)254)209-162(273)113(51-57-143(255)256)210-164(275)115(59-67-295-15)211-160(271)110(47-53-133(188)242)207-157(268)106(40-25-27-60-185)206-172(283)126(86-237)224-167(278)118(70-92(6)7)216-169(280)123(76-145(259)260)220-173(284)128(88-239)226-180(291)149(98(14)241)230-171(282)120(72-100-36-21-18-22-37-100)221-179(290)148(97(13)240)227-138(247)82-199-153(264)109(48-54-140(249)250)204-137(246)81-197-152(263)104(187)74-102-78-193-89-201-102/h17-24,34-39,77-78,89-98,104,106-132,146-149,195,235-241H,16,25-33,40-76,79-88,185-187H2,1-15H3,(H2,188,242)(H2,189,243)(H2,190,261)(H,193,201)(H,196,244)(H,197,263)(H,198,265)(H,199,264)(H,200,266)(H,202,245)(H,203,267)(H,204,246)(H,205,276)(H,206,283)(H,207,268)(H,208,272)(H,209,273)(H,210,275)(H,211,271)(H,212,288)(H,213,289)(H,214,270)(H,215,279)(H,216,280)(H,217,277)(H,218,274)(H,219,269)(H,220,284)(H,221,290)(H,222,287)(H,223,285)(H,224,278)(H,225,286)(H,226,291)(H,227,247)(H,228,262)(H,229,281)(H,230,282)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,259,260)(H4,191,192,194)/t94?,95-,96-,97?,98?,104-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,146-,147-,148-,149-/m0/s1 HTQBXNHDCUEHJF-URRANESESA-N 4186.57200 4184.02731 CCC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)C(C)O)C(C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O CAS:141758-74-9 KEGG:C15894 KEGG:D04121 PMID:12364473 PMID:1313797 PMID:14565957 PMID:16353670 PMID:17053883 PMID:20149450 PMID:20404826 PMID:22310470 PMID:22334721 PMID:22338110 PMID:22356440 PMID:22363635 PMID:22384126 Patent:EP1908778 Reaxys:9040649 Wikipedia:Exenatide L-histidylglycyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serinamide exendin-4 chebi_ontology Ex4 Exendin 4 Heloderma suspectum gila monster exendin-4 His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 exenatida exenatide exenatidum CHEBI:64073 exendin-4 A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. 0 C12H21N InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3 BUGYDGFZZOZRHP-UHFFFAOYSA-N 179.30180 179.16740 CC12CC3CC(C)(C1)CC(N)(C3)C2 CHEBI:34832 CAS:19982-08-2 DrugBank:DB01043 Drug_Central:1679 KEGG:C13736 KEGG:D08174 LINCS:LSM-5154 PMID:20104942 PMID:21953515 PMID:21955815 PMID:22030128 PMID:22134197 PMID:22245025 PMID:22248638 PMID:22290557 PMID:22297273 PMID:22300835 PMID:22311362 PMID:22327556 PMID:22329473 PMID:22392787 PMID:22414570 PMID:22425751 Patent:US2011282100 Reaxys:2075983 Wikipedia:Memantine 3,5-dimethyladamantan-1-amine chebi_ontology 1,3-Dimethyl-5-adamantanamine 1-Amino-3,5-dimethyladamantane 3,5-Dimethyl-1-adamantanamine 3,5-Dimethyl-1-aminoadamantane 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine memantina memantine memantinum CHEBI:64312 memantine An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond. chebi_ontology biaryls CHEBI:64459 biaryl A glycerophosphocholine that is glycero-3-phosphocholine bearing two acyl substituents at positions 1 and 2. 0 C10H18NO8PR2 311.226 311.07700 C[N+](C)(C)CCOP([O-])(=O)OCC(COC([*])=O)OC([*])=O PMID:2474544 2,3-bis(acyloxy)propyl 2-(trimethylammonio)ethyl phosphate chebi_ontology 1,2-diacyl-glycero-3-phosphocholine a phosphatidylcholine (0) CHEBI:64482 phosphatidylcholine Any of a class of phospholipids in which the amino group of a sphingoid base is in amide linkage with one of several fatty acids, while the terminal hydroxy group of the sphingoid base is esterified to phosphorylcholine. 0 C9H19N2O6PR2 282.23070 282.09807 C[N+](C)(C)CCOP([O-])(=O)OC[C@H](NC([*])=O)[C@H](O)[*] LIPID_MAPS_class:LMSP0301 PMID:27242221 chebi_ontology Ceramide phosphocholine an N-(acyl)-sphingosylphosphocholine CHEBI:64583 sphingomyelin A peptide of 36-43 amino acids that is processed from the amyloid precursor protein. Appears to be the main constituent of amyloid plaques (deposits found in the brains of Alzheimer's disease patients). Alzpathway: APOE-AmyloidB leading to Unknown transportation; APOE-AmyloidB association. Source: https://pubmed.ncbi.nlm.nih.gov/33679311/ Alzpathway: AmyloidB-CLU dissociation; AmyloidB-CLU association_Brain; AmyloidB-CLU leading to Unknown transportation. Source: https://pubmed.ncbi.nlm.nih.gov/30872998/ CHEBI:53002 KEGG:C16514 KEGG:C16515 PMID:21892760 PMID:22226401 PMID:22457725 PMID:22459190 PMID:22561032 PMID:22569063 Wikipedia:Beta_amyloid chebi_ontology amyloid beta beta amyloid beta-amyloid beta-amyloids CHEBI:64645 amyloid-beta Any organic molecular entity that is acidic and contains carbon in covalent linkage. chebi_ontology organic acids CHEBI:64709 organic acid A C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds. 0 C20H32O5 InChI=1S/C20H32O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h4-7,9-10,13-14,17-19,21-23H,2-3,8,11-12,15-16H2,1H3,(H,24,25)/b6-4-,7-5+,13-9+,14-10+/t17-,18+,19-/m0/s1 IXAQOQZEOGMIQS-SSQFXEBMSA-N 352.46508 352.22497 CCCCC[C@H](O)\C=C\C=C/C=C/C=C/[C@@H](O)[C@@H](O)CCCC(O)=O HMDB:HMDB0004385 KEGG:C06314 LIPID_MAPS_instance:LMFA03040001 PMID:20435922 PMID:20802423 PMID:20833483 PMID:20950211 PMID:20959513 PMID:21263017 PMID:8690917 Reaxys:4698639 (5S,6R,7E,9E,11Z,13E,15S)-5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid Lipoxin A4 lipoxin A4 chebi_ontology (5S,6R,15S)-trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic acid (5S,6R,7E,9E,11Z,13E,15S)-5,6,15-trihydroxy-7,9,11,13-eicosatetraenoic acid (5S,6R,7E,9E,11Z,13E,15S)-5,6,15-trihydroxyeicosa-7,9,11,13-tetraenoic acid (7E,9E,11Z,13E)-(5S,6R,15S)-5,6,15-Trihydroxyicosa-7,9,11,13-tetraenoic acid 5(S),6(R),15(S)-trihydroxyeicosa-7E,9E,11Z,13E-tetraenoic acid 5S,6R,15S-Trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid 5S,6R,15S-trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic acid 5S,6R-LipoxinA4 6R-LXA4 LXA4 CHEBI:6498 lipoxin A4 0 C22H23ClN2O2 InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3 JCCNYMKQOSZNPW-UHFFFAOYSA-N 382.884 382.14481 CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1 CHEBI:94763 CAS:79794-75-5 Drug_Central:1605 HMDB:HMDB0005000 KEGG:D00364 LINCS:LSM-5891 Loratadine chebi_ontology Claritin (TN) claritin loracert loradex loratidine loratyne CHEBI:6538 Loratadine 0 C15H10Cl2N2O2 InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20) DIWRORZWFLOCLC-UHFFFAOYSA-N 321.159 320.01193 C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O)Cl CHEBI:94326 CAS:846-49-1 Drug_Central:1606 HMDB:HMDB0014332 KEGG:D00365 LINCS:LSM-4970 Lorazepam chebi_ontology Wy 4036 Wy-4036 ativan CHEBI:6539 Lorazepam 0 C20H23N InChI=1S/C20H23N/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20/h2-5,7-10,15,21H,6,11-14H2,1H3 QSLMDECMDJKHMQ-UHFFFAOYSA-N 277.404 277.18305 CNCCCC12CCC(c3ccccc13)c1ccccc21 CAS:10262-69-8 Drug_Central:1634 HMDB:HMDB0015069 KEGG:C07107 KEGG:D02566 LINCS:LSM-2043 Maprotiline chebi_ontology maprotiline HCl maprotiline hydrochloride CHEBI:6690 Maprotiline An N-acyl-L-alpha-amino acid anion obtained by deprotonation of any folic acid. chebi_ontology folate folate anion folate anions CHEBI:67011 folates Any compound that has anti-inflammatory effects. chebi_ontology anti-inflammatory agents antiinflammatory agent antiinflammatory agents CHEBI:67079 anti-inflammatory agent An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis. 0 C14H11Cl2NO2 InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19) SBDNJUWAMKYJOX-UHFFFAOYSA-N 296.14900 295.01668 Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl CAS:644-62-2 DrugBank:DB00939 Drug_Central:1650 HMDB:HMDB0015074 KEGG:C07117 KEGG:D02341 LINCS:LSM-3108 PDBeChem:JMS PMID:15598972 PMID:16986603 PMID:17348907 PMID:1810521 PMID:19279153 PMID:21660425 PMID:23534549 PMID:23567745 PMID:23584353 PMID:322627 PMID:7349327 Patent:DE1149045 Patent:US3313848 Reaxys:2221428 Wikipedia:Meclofenamic_acid 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid chebi_ontology CI-583 INF 4668 N-(2,6-dichloro-3-methylphenyl)anthranilic acid N-(2,6-dichloro-m-tolyl)anthranilic acid N-(3-methyl-2,6-dichlorophenyl)anthranilic acid acide meclofenamique acido meclofenamico acidum meclofenamicum meclofenamic acid CHEBI:6710 meclofenamic acid An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis. 0 C15H15NO2 InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18) HYYBABOKPJLUIN-UHFFFAOYSA-N 241.28510 241.11028 Cc1cccc(Nc2ccccc2C(O)=O)c1C CAS:61-68-7 DrugBank:DB00784 Drug_Central:1663 HMDB:HMDB0014922 KEGG:C02168 KEGG:D00151 LINCS:LSM-4085 PDBeChem:ID8 PMID:14001132 PMID:17330662 PMID:22275128 PMID:22369458 PMID:23402341 PMID:23494912 PMID:23656341 PMID:2684858 PMID:28166217 PMID:3304401 PMID:4212650 PMID:425903 PMID:4916242 PMID:5286553 PMID:577447 PMID:6155061 Patent:BE605302 Patent:US3138636 Reaxys:2216243 Wikipedia:Mefenamic_acid 2-[(2,3-dimethylphenyl)amino]benzoic acid chebi_ontology CI-473 CN 35355 CN-35355 INF 3355 INF-3355 Mefenaminsaeure N-(2,3-xylyl)-2-aminobenzoic acid N-2,3-xylylanthranilic acid Ponstel acide mefenamique acido mefenamico acidum mefenamicum mefenamic acid CHEBI:6717 mefenamic acid A benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis. 0 C14H13N3O4S2 InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19) ZRVUJXDFFKFLMG-UHFFFAOYSA-N 351.40100 351.03475 CN1C(C(=O)Nc2ncc(C)s2)=C(O)c2ccccc2S1(=O)=O CAS:71125-38-7 DrugBank:DB00814 Drug_Central:1676 HMDB:HMDB0014952 KEGG:C08169 KEGG:D00969 PMID:10092958 PMID:12387696 PMID:16197363 PMID:16623613 PMID:16863437 PMID:18405470 PMID:19821429 PMID:23306395 PMID:23388116 PMID:23406022 PMID:24041211 PMID:24084190 PMID:28166217 PMID:8882380 PMID:9219316 Patent:DE2756113 Patent:US4233299 Reaxys:5886369 VSDB:1751 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide chebi_ontology Mobic UNII-VG2QF83CGL meloxicam meloxicamum CHEBI:6741 meloxicam A phenothiazine substituted at position 2 (para to the S atom) by a methylsulfinyl group, and on the nitrogen by a 2-(1-methylpiperidin-2-yl)ethyl group. 0 C21H26N2OS2 InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 SLVMESMUVMCQIY-UHFFFAOYSA-N 386.57400 386.14866 CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O CHEBI:248004 CAS:5588-33-0 DrugBank:DB00933 Drug_Central:1712 KEGG:C07143 KEGG:D02671 LINCS:LSM-1329 Patent:US3084161 Reaxys:1033986 Wikipedia:Mesoridazine 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfinyl)-10H-phenothiazine Mesoridazine chebi_ontology 10-(2(1-Methyl-2-piperidyl)ethyl)-2-(methylsulfinyl)phenothiazine 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylsulfinyl phenothiazine 2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine TPS-23 mesoridazina mesoridazine mesoridazinum thioridazine thiomethyl sulfoxide thioridazine-2-sulfoxide CHEBI:6780 mesoridazine A member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively. 0 C19H24N2OS InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m1/s1 VRQVVMDWGGWHTJ-CQSZACIVSA-N 328.47274 328.16093 COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1 Beilstein:92434 CAS:60-99-1 DrugBank:DB01403 Drug_Central:1752 HMDB:HMDB0015474 KEGG:C07192 KEGG:D00403 KEGG:D06474 LINCS:LSM-2778 PMID:11026079 PMID:11260766 PMID:15700129 PMID:20825390 Patent:US2837518 Reaxys:92434 Wikipedia:Levomepromazine (2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine Methotrimeprazine chebi_ontology (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine 2-Methoxytrimeprazine Levomepromazine levomepromazina levomepromazine levomepromazinum CHEBI:6838 methotrimeprazine A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group. 0 C4H8Cl3O4P InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 NFACJZMKEDPNKN-UHFFFAOYSA-N 257.43700 255.92258 COP(=O)(OC)C(O)C(Cl)(Cl)Cl Beilstein:1709434 CAS:52-68-6 Drug_Central:1787 KEGG:C07971 KEGG:D00805 LINCS:LSM-4995 PMID:19775726 PMID:24122545 PPDB:657 Reaxys:1709434 VSDB:657 Wikipedia:Metrifonate Trichlorfon dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate chebi_ontology (+-)-Trichlorfon 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester Chlorophos Methyl chlorophos Metrifonate metrifonate metrifonato metrifonatum CHEBI:6908 trichlorfon 0 C17H19N3 InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3 RONZAEMNMFQXRA-UHFFFAOYSA-N 265.35290 265.15790 CN1CCN2C(C1)c1ccccc1Cc1cccnc21 Beilstein:549345 CAS:61337-67-5 DrugBank:DB00370 Drug_Central:1816 KEGG:C07570 KEGG:D00563 LINCS:LSM-1706 PMID:10446735 PMID:10653218 PMID:16965209 PMID:18548827 PMID:33163376 PMID:33422759 PMID:33559900 PMID:33685359 PMID:33841403 PMID:33856954 Patent:DE2614406 Patent:US4062848 VSDB:2980 Wikipedia:Mirtazapine 2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine Mirtazapine chebi_ontology 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine mirtazapina mirtazapine mirtazapinum CHEBI:6950 mirtazapine 0 C27H34N2O7 InChI=1S/C27H34N2O7/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32)/t17-,21-,22-/m0/s1 UWWDHYUMIORJTA-HSQYWUDLSA-N 498.569 498.23660 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2cc(OC)c(OC)cc2C[C@H]1C(O)=O CAS:103775-10-6 Drug_Central:1827 HMDB:HMDB0014829 KEGG:C07704 KEGG:D08225 LINCS:LSM-2751 Moexipril chebi_ontology moclobenid moexipril HCl moexipril hydrochloride CHEBI:6960 Moexipril A lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. 0 C172H265N43O51 InChI=1S/C172H265N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-129(224)195-116(170(265)266)59-64-128(223)180-68-41-40-50-111(153(248)199-115(62-67-135(232)233)154(249)204-120(73-100-44-33-31-34-45-100)159(254)214-140(93(11)19-2)167(262)192-97(15)146(241)201-122(76-103-79-183-108-49-39-38-48-106(103)108)157(252)203-118(72-90(5)6)158(253)212-138(91(7)8)165(260)200-110(52-43-70-182-172(177)178)149(244)184-81-130(225)193-109(51-42-69-181-171(175)176)148(243)187-84-137(236)237)196-144(239)95(13)189-143(238)94(12)191-152(247)114(58-63-127(174)222)194-131(226)82-185-151(246)113(61-66-134(230)231)198-155(250)117(71-89(3)4)202-156(251)119(75-102-54-56-105(221)57-55-102)205-162(257)124(85-216)208-164(259)126(87-218)209-166(261)139(92(9)10)213-161(256)123(78-136(234)235)206-163(258)125(86-217)210-169(264)142(99(17)220)215-160(255)121(74-101-46-35-32-36-47-101)207-168(263)141(98(16)219)211-132(227)83-186-150(245)112(60-65-133(228)229)197-145(240)96(14)190-147(242)107(173)77-104-80-179-88-188-104/h31-36,38-39,44-49,54-57,79-80,88-99,107,109-126,138-142,183,216-221H,18-30,37,40-43,50-53,58-78,81-87,173H2,1-17H3,(H2,174,222)(H,179,188)(H,180,223)(H,184,244)(H,185,246)(H,186,245)(H,187,243)(H,189,238)(H,190,242)(H,191,247)(H,192,262)(H,193,225)(H,194,226)(H,195,224)(H,196,239)(H,197,240)(H,198,250)(H,199,248)(H,200,260)(H,201,241)(H,202,251)(H,203,252)(H,204,249)(H,205,257)(H,206,258)(H,207,263)(H,208,259)(H,209,261)(H,210,264)(H,211,227)(H,212,253)(H,213,256)(H,214,254)(H,215,255)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,265,266)(H4,175,176,181)(H4,177,178,182)/t93-,94-,95-,96-,97-,98+,99+,107-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,138-,139-,140-,141-,142-/m0/s1 YSDQQAXHVYUZIW-QCIJIYAXSA-N 3751.20200 3748.94646 CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O)C(O)=O CAS:204656-20-2 DrugBank:DB06655 Drug_Central:4164 KEGG:D06404 PMID:21964769 PMID:22038829 PMID:22051096 PMID:22245694 PMID:22338093 PMID:22382611 PMID:22405264 PMID:22443187 PMID:22446097 PMID:22536087 PMID:22569791 PMID:22587909 PMID:22592020 PMID:22727533 PMID:22846777 PMID:22851600 PMID:22862847 PMID:22927782 PMID:22938097 PMID:22958381 PMID:22973968 PMID:22985213 PMID:23068961 PMID:23082308 PMID:23149376 Patent:US2006160736 Patent:WO2008011518 Reaxys:10331362 Wikipedia:Liraglutide N2()-(L-histidyl-L-alanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl)-N(6)-(N-hexadecanoyl-L-gamma-glutamyl)-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine chebi_ontology NN 2211 NN-2211 NN2211 Victoza liraglutida liraglutide liraglutidum CHEBI:71193 liraglutide A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug. 0 C15H15NO3 InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18) UPSPUYADGBWSHF-UHFFFAOYSA-N 257.28450 257.10519 Cc1ccc(cc1)C(=O)c1ccc(CC(O)=O)n1C CHEBI:9618 CAS:26171-23-3 DrugBank:DB00500 Drug_Central:2699 HMDB:HMDB0014643 KEGG:C07149 KEGG:D02355 LINCS:LSM-3852 PDBeChem:TLT PMID:1206489 PMID:19181568 PMID:19505209 PMID:20529813 PMID:20582193 PMID:20853464 PMID:21936545 PMID:22005020 PMID:22943177 PMID:23333829 PMID:3390998 PMID:445955 PMID:6686452 PMID:8472518 Patent:DE2836902 Patent:MX2010012712 Patent:WO2004069782 Patent:WO2008017903 Patent:WO2009072139 Reaxys:485305 Wikipedia:Tolmetin [1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid chebi_ontology 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid 1-Methyl-5-p-toluoylpyrrole-2-acetic acid 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid tolmetin tolmetina tolmetine tolmetino tolmetinum CHEBI:71941 tolmetin Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them. Wikipedia:Flavonoids chebi_ontology flavonoid CHEBI:72544 flavonoids Any molecule that consists of at least one carbon atom as part of the electrically neutral entity. chebi_ontology organic compound organic compounds organic molecules CHEBI:72695 organic molecule An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity. 0 C15H13ClFNO2 InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) KHPKQFYUPIUARC-UHFFFAOYSA-N 293.72100 293.06188 Cc1ccc(Nc2c(F)cccc2Cl)c(CC(O)=O)c1 CAS:220991-20-8 DrugBank:DB01283 Drug_Central:1618 HMDB:HMDB0015403 KEGG:D03714 PDBeChem:LUR PMID:14965322 PMID:15311562 PMID:15456339 PMID:17380211 PMID:19800190 PMID:21688392 PMID:22069133 PMID:22142375 PMID:22621454 PMID:22732767 Reaxys:9784107 Wikipedia:Lumiracoxib {2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid chebi_ontology 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid COX 189 COX-189 COX189 Prexige lumiracoxib lumiracoxibum CHEBI:73044 lumiracoxib A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine 0 C21H21ClN2O InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3 RAVIZVQZGXBOQO-UHFFFAOYSA-N 352.85700 352.13424 CCC(C)N(C)C(=O)c1cc2ccccc2c(n1)-c1ccccc1Cl Beilstein:4264456 CAS:85532-75-8 LINCS:LSM-1532 PMID:22528948 PMID:23358477 PMID:23597562 PMID:23611861 Reaxys:4264456 Wikipedia:PK-11195 N-sec-butyl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide chebi_ontology 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide PK11195 RP 52028 CHEBI:73290 PK-11195 A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs. 0 C15H16O2 InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3 BLXXJMDCKKHMKV-UHFFFAOYSA-N 228.28630 228.11503 COc1ccc2cc(CCC(C)=O)ccc2c1 Beilstein:2103472 CAS:42924-53-8 DrugBank:DB00461 Drug_Central:1863 HMDB:HMDB0014604 KEGG:D00425 LINCS:LSM-3453 PDBeChem:NBO PMID:21532165 PMID:21650014 PMID:21674107 PMID:21898684 PMID:22028826 PMID:22298755 PMID:22381180 PMID:22605805 PMID:22977877 PMID:23020786 PMID:23129452 PMID:23132511 PMID:23225308 PMID:23584048 PMID:23781467 PMID:23781476 PMID:23806470 PMID:24074034 PMID:24083957 Reaxys:2103472 Wikipedia:Nabumetone chebi_ontology 4-(6-Methoxy-2-naphthalenyl)-2-butanone 4-(6-Methoxy-2-naphthyl)-2-butanone Relafen nabumetona nabumetone nabumetonum CHEBI:7443 nabumetone A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes. 0 C14H14O3 InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1 CMWTZPSULFXXJA-VIFPVBQESA-N 230.25920 230.09429 COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O CHEBI:603695 Beilstein:3591067 CAS:22204-53-1 DrugBank:DB00788 Drug_Central:1883 HMDB:HMDB0001923 KEGG:D00118 LINCS:LSM-5689 PMID:18044350 PMID:24478225 PMID:9784154 Patent:US3904682 Patent:US4009197 Wikipedia:Naproxen (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid Naproxen naproxen chebi_ontology (+)-(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid (+)-(S)-Naproxen (+)-2-(6-Methoxy-2-naphthyl)propionic acid (+)-2-(Methoxy-2-naphthyl)-propionic acid (+)-2-(Methoxy-2-naphthyl)-propionsaeure (+)-Naproxen (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid (S)-(+)-Naproxen (S)-2-(6-Methoxy-2-naphthyl)propanoic acid (S)-2-(6-Methoxy-2-naphthyl)propionic acid (S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid (S)-Naproxen naproxen naproxene naproxeno naproxenum CHEBI:7476 naproxen An organic sodium salt consisting of equimolar amounts of naproxen(1-) anions and sodium anions. 0 C14H13NaO3 C14H13O3.Na InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1 CDBRNDSHEYLDJV-FVGYRXGTSA-M 252.24100 252.07624 [Na+].COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O Beilstein:6378035 CAS:26159-34-2 DrugBank:DB00788 KEGG:D00970 sodium (2S)-2-(6-methoxy-2-naphthyl)propanoate chebi_ontology (-)-Sodium (S)-6-methoxy-alpha-methyl-2-naphthaleneacetate CHEBI:7477 naproxen sodium An enzyme inhibitor that inhibits the activity of gamma-secretase. Wikipedia:Gamma_secretase Gamma-secretase inhibitor chebi_ontology Gamma-secretase inhibitors gamma-secretase inhibitors CHEBI:74925 gamma-secretase inhibitor 0 C25H32ClN5O2 InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3 VRBKIVRKKCLPHA-UHFFFAOYSA-N 470.00700 469.22445 CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CCOc1ccccc1 Beilstein:4728403 CAS:83366-66-9 DrugBank:DB01149 Drug_Central:1890 KEGG:C07256 KEGG:D08257 LINCS:LSM-4031 Patent:US4338317 Wikipedia:Nefazodone 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one Nefazodone nefazodone chebi_ontology 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one nefazodona nefazodone nefazodonum CHEBI:7494 nefazodone A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor. +1 C12H19N2O2 InChI=1S/C12H19N2O2/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5/h6-9H,1-5H3/q+1 ALWKGYPQUAPLQC-UHFFFAOYSA-N 223.29150 223.14410 CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C Beilstein:3615946 CAS:59-99-4 DrugBank:DB01400 Drug_Central:1897 HMDB:HMDB0015472 KEGG:C07258 KEGG:D08261 LINCS:LSM-5360 PMID:7200780 PMID:8584207 Reaxys:3615946 Wikipedia:Neostigmine 3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium chebi_ontology (m-Hydroxyphenyl)trimethylammonium dimethylcarbamate 3-Trimethylammoniumphenyl N,N-dimethylcarbamate Eustigmin Eustigmine Prostigmine Vagostigmine m-Trimethylammoniumphenyldimethylcarbamate CHEBI:7514 neostigmine A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm. 0 C21H26N2O7 InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3 UIAGMCDKSXEBJQ-UHFFFAOYSA-N 418.44030 418.17400 COCCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC(C)C CAS:66085-59-4 DrugBank:DB00393 Drug_Central:1937 KEGG:C07267 KEGG:D00438 LINCS:LSM-1659 PMID:12137606 PMID:16180362 PMID:17110283 PMID:21869451 PMID:22262041 PMID:22300914 PMID:8519001 Patent:DE2117571 Patent:US3799934 Reaxys:459792 Wikipedia:Nimodipine 2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Nimodipine chebi_ontology 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester BAY e 9736 Nimotop Periplum isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate nimodipine nimodipino nimodipinum CHEBI:7575 nimodipine A ketone in which the carbonyl group is attached to an aromatic ring. chebi_ontology aromatic ketones aryl ketone aryl ketones CHEBI:76224 aromatic ketone An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline. 0 C19H21N InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-11,20H,6,12-14H2,1H3 PHVGLTMQBUFIQQ-UHFFFAOYSA-N 263.37678 263.16740 CNCCC=C1c2ccccc2CCc2ccccc12 Beilstein:2216786 CAS:72-69-5 DrugBank:DB00540 Drug_Central:1971 HMDB:HMDB0014680 KEGG:C07274 KEGG:D08288 LINCS:LSM-4039 PDBeChem:21B PMID:10379421 PMID:14561440 PMID:17071817 PMID:23280809 PMID:24037379 PMID:24368464 PMID:25224004 PMID:25480462 PMID:25569864 PMID:25592638 PMID:25683584 PMID:25707462 PMID:25749306 PMID:26086857 PMID:26453560 Patent:NL6408512 Patent:US3442949 Patent:US3922305 Reaxys:2216786 Wikipedia:Nortriptyline 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine Nortriptyline chebi_ontology 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Delta(5,gamma)-propylamine 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine Ateben Avantyl Aventyl Noritren Psychostyl Sensaval demethylamitriptyline desmethylamitriptyline nortriptylina nortriptyline nortriptylinum CHEBI:7640 nortriptyline A benzodiazepine that is 10H-thieno[2,3-b][1,5]benzodiazepine substituted by a methyl group at position 2 and a 4-methylpiperazin-1-yl group at position 4. 0 C17H20N4S InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 312.434 312.14087 N1=C(C2=C(NC3=CC=CC=C13)SC(=C2)C)N4CCN(CC4)C CAS:132539-06-1 DrugBank:DB00334 Drug_Central:1982 KEGG:C07322 KEGG:D00454 PMID:18022155 PMID:18504690 PMID:18792627 Patent:EP454436 Patent:US5229382 Reaxys:7655141 Wikipedia:Olanzapine 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine Olanzapine chebi_ontology Zyprexa olanzapina olanzapine olanzapinum CHEBI:7735 olanzapine A monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis. 0 C18H15NO3 InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21) OFPXSFXSNFPTHF-UHFFFAOYSA-N 293.31660 293.10519 OC(=O)CCc1nc(-c2ccccc2)c(o1)-c1ccccc1 CAS:21256-18-8 DrugBank:DB00991 Drug_Central:2013 HMDB:HMDB0015126 KEGG:C07356 KEGG:D00463 LINCS:LSM-2553 PMID:1603605 PMID:1617910 PMID:19338579 PMID:19672323 PMID:20206429 PMID:23865335 PMID:385873 PMID:6432657 PMID:6611288 PMID:6863578 PMID:9459947 Patent:FR2001036 Patent:GB1206403 Patent:US3578671 Patent:WO2007082542 Reaxys:1083168 Wikipedia:Oxaprozin 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid chebi_ontology Danoprox Daypro Dayrun Deflam Duraprox Walix oxaprozin oxaprozina oxaprozine oxaprozinum CHEBI:7822 oxaprozin A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5. 0 C15H11ClN2O2 InChI=1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19) ADIMAYPTOBDMTL-UHFFFAOYSA-N 286.71300 286.05091 OC1N=C(c2ccccc2)c2cc(Cl)ccc2NC1=O CAS:604-75-1 DrugBank:DB00842 Drug_Central:2015 HMDB:HMDB0014980 KEGG:C07359 KEGG:D00464 PMID:17456431 PMID:9811432 Patent:CN1543961 Reaxys:754065 Wikipedia:Oxazepam 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one Oxazepam chebi_ontology (+-)-Oxazepam (RS)-Oxazepam Serax Tazepam CHEBI:7823 oxazepam A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants. chebi_ontology dietary component dietary components food components CHEBI:78295 food component A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. 0 C15H18N2O InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15+/m0/s1 ZRJBHWIHUMBLCN-YQEJDHNASA-N 242.31620 242.14191 C\C=C1/[C@@H]2Cc3[nH]c(=O)ccc3[C@@]1(N)CC(C)=C2 CAS:102518-79-6 DrugBank:DB04864 PMID:12895686 PMID:23306162 PMID:24129696 PMID:24190328 PMID:24299147 PMID:24332448 PMID:24639880 Reaxys:3592896 Wikipedia:Huperzine_A (5R,9R,11E)-5-amino-11-ethylidene-7-methyl-5,6,9,10-tetrahydro-5,9-methanocycloocta[b]pyridin-2(1H)-one chebi_ontology (-)-huperazine A (-)-selagine selagine CHEBI:78330 huperzine A Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation. chebi_ontology carbohydrates and derivatives carbohydrates and their derivatives CHEBI:78616 carbohydrates and carbohydrate derivatives A squalene triterpenoid obtained by formal epoxidation across the 2,3 C=C bond of squalene. 0 C30H50O InChI=1S/C30H50O/c1-24(2)14-11-17-27(5)20-12-18-25(3)15-9-10-16-26(4)19-13-21-28(6)22-23-29-30(7,8)31-29/h14-16,20-21,29H,9-13,17-19,22-23H2,1-8H3/b25-15+,26-16+,27-20+,28-21+ QYIMSPSDBYKPPY-BANQPHDMSA-N 426.71740 426.38617 CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CCC1OC1(C)C CAS:7200-26-2 Reaxys:1627703 2,2-dimethyl-3-[(3E,7E,11E,15E)-3,7,12,16,20-pentamethylhenicosa-3,7,11,15,19-pentaen-1-yl]oxirane chebi_ontology 2,3-Edsq 2,3-Epoxy-2,3-dihydrosqualene 2,3-Oxidosqualene Squalene-2,3-epoxide Squalene-2,3-oxide CHEBI:78662 2,3-epoxysqualene A benzodioxole that consists of piperidine bearing 1,3-benzodioxol-5-yloxy)methyl and 4-fluorophenyl substituents at positions 3 and 4 respectively; the (3S,4R)-diastereomer. Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for alpha1-, alpha2- or beta-adrenoceptors, 5-HT2A, 5-HT1A, D2 or H1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo. 0 C19H20FNO3 InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 329.36540 329.14272 [H][C@]1(CCNC[C@H]1COc1ccc2OCOc2c1)c1ccc(F)cc1 Beilstein:7467879 CAS:61869-08-7 DrugBank:DB00715 Drug_Central:2068 KEGG:C07415 KEGG:D02362 LINCS:LSM-2843 PMID:11009210 PMID:11169163 PMID:11271409 PMID:11281965 PMID:11324355 PMID:11360029 PMID:11513198 PMID:11563413 PMID:11565622 PMID:11819027 PMID:11893234 PMID:11910269 PMID:12027788 PMID:12088162 PMID:12369443 PMID:12421645 PMID:12818234 PMID:12820211 PMID:12906023 PMID:12920419 PMID:14516531 PMID:14521492 PMID:14566196 PMID:14566200 PMID:14619895 PMID:14624192 PMID:14673053 PMID:14689334 PMID:14978354 PMID:15048901 PMID:15199661 PMID:15241233 PMID:15264994 PMID:15374134 PMID:15376524 PMID:15544025 PMID:15613191 PMID:15845695 PMID:15853570 PMID:15903129 PMID:15963219 PMID:15992089 PMID:16395417 PMID:16397315 PMID:16426087 PMID:16765127 PMID:16822276 PMID:16913391 PMID:17122538 PMID:17162096 PMID:17219219 PMID:17286545 PMID:17452166 PMID:17559097 PMID:17612590 PMID:17652957 PMID:17874333 PMID:18273418 PMID:18345955 PMID:18808757 PMID:18983224 PMID:19687003 PMID:19851065 PMID:21404089 PMID:21452176 PMID:21739267 PMID:21908494 PMID:21909633 PMID:21922171 PMID:21939725 PMID:22153922 PMID:22198456 PMID:22212003 PMID:22240860 PMID:22263916 PMID:22283559 PMID:22353759 PMID:22377745 Reaxys:7467879 Wikipedia:Paroxetine (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Paroxetine chebi_ontology (-)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine paroxetina paroxetinum CHEBI:7936 paroxetine KEGG:C15901 chebi_ontology CHEBI:80161 Galanin An alpha-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline 0 C19H32N2O5 InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15-,16-/m0/s1 IPVQLZZIHOAWMC-QXKUPLGCSA-N 368.46786 368.23112 [H][C@@]12CCCC[C@]1([H])N([C@@H](C2)C(O)=O)C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC CAS:82834-16-0 DrugBank:DB00790 Drug_Central:2108 HMDB:HMDB0014928 KEGG:C07706 KEGG:D03753 LINCS:LSM-4080 PMID:24291100 PMID:24324048 PMID:24357222 PMID:24511479 PMID:24515310 PMID:24554346 PMID:24590580 PMID:24602481 PMID:24664905 Reaxys:4300272 Wikipedia:Perindopril ethyl N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvalinate chebi_ontology (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid perindopril perindoprilum CHEBI:8024 perindopril KEGG:C16048 chebi_ontology GLP-1 CHEBI:80270 Glucagon-like peptide 1 A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10. 0 C21H26ClN3OS InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 RGCVKNLCSQQDEP-UHFFFAOYSA-N 403.96946 403.14851 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 Beilstein:54730 CAS:58-39-9 DrugBank:DB00850 Drug_Central:2113 HMDB:HMDB0014988 KEGG:C07427 KEGG:D00503 LINCS:LSM-2224 PMID:14401911 PMID:15674907 PMID:1650428 PMID:26660173 PMID:27150024 Patent:US2766235 Patent:US2860138 Reaxys:54730 Wikipedia:Perphenazine 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol Perphenazine chebi_ontology 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol 2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol Chlorpiprazine Perfenazine Perphenazin Trilafon gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine perfenazina perphenazine perphenazinum CHEBI:8028 perphenazine 0 C8H12N2 InChI=1S/C8H12N2/c9-10-7-6-8-4-2-1-3-5-8/h1-5,10H,6-7,9H2 RMUCZJUITONUFY-UHFFFAOYSA-N 136.195 136.10005 NNCCc1ccccc1 CAS:51-71-8 Drug_Central:2123 HMDB:HMDB0014918 KEGG:C07430 KEGG:D08349 LINCS:LSM-5928 Phenelzine chebi_ontology 1-hydrazino-2-phenylethane 2-phenylethylhydrazine phenalzine phenelzine sulfate phenethylhydrazine CHEBI:8060 Phenelzine A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which one of the nitrogens is substituted by a piperidin-4-yl group, which in turn is substituted on the nitrogen by a 4,4-bis(p-fluorophenyl)butyl group. 0 C28H29F2N3O InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 461.54620 461.22787 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 Beilstein:729089 CAS:2062-78-4 DrugBank:DB01100 Drug_Central:2172 HMDB:HMDB0015232 KEGG:C07566 KEGG:D00560 LINCS:LSM-2001 Reaxys:729089 Wikipedia:Pimozide 1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one Pimozide pimozide chebi_ontology Halomonth Neoperidole Opiran Orap pimozida pimozide pimozidum CHEBI:8212 pimozide A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity. 0 C19H20N2O3S InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23) HYAFETHFCAUJAY-UHFFFAOYSA-N 356.43978 356.11946 CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1 Beilstein:3595485 CAS:111025-46-8 Chemspider:4663 DrugBank:DB01132 Drug_Central:2179 HMDB:HMDB0015264 KEGG:C07675 KEGG:D08378 LINCS:LSM-1592 PMID:12879407 PMID:14522601 PMID:18215232 PMID:20797618 PMID:27842070 PMID:33798599 PMID:33864097 PMID:33983968 PMID:33995271 PMID:34006325 PMID:34009030 Patent:EP193256 Patent:US4687777 Reaxys:3595485 Wikipedia:Pioglitazone 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione Pioglitazone chebi_ontology (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione pioglitazona pioglitazone pioglitazonum CHEBI:8228 pioglitazone A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide with the exocyclic nitrogen of 2-aminopyridine. A non-steroidal anti-inflammatory drug of the oxicam class, it is used to relieve pain and works by preventing the production of endogenous prostaglandins involved in the mediation of pain, stiffness, tenderness and swelling. 0 C15H13N3O4S InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20) QYSPLQLAKJAUJT-UHFFFAOYSA-N 331.34600 331.06268 CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O Beilstein:627692 CAS:36322-90-4 DrugBank:DB00554 Drug_Central:2210 HMDB:HMDB0014694 KEGG:C01608 KEGG:D00127 PMID:11142413 PMID:12154043 PMID:28166217 Patent:DE1943265 Patent:US3591584 Reaxys:627692 Wikipedia:Piroxicam 4-hydroxy-2-methyl-N-pyridin-2-yl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide Piroxicam chebi_ontology 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid FELDENE Feldene Pyroxycam piroxicam piroxicamum CHEBI:8249 piroxicam An aromatic amide obtained by formal condensation of the carboxy group of 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid with the secondary amino group of 5-chloro-2-[(5R)-5-methyl-1,4-diazepan-1-yl]-1,3-benzoxazole. An orexin receptor antagonist used for the management of insomnia. 0 C23H23ClN6O2 InChI=1S/C23H23ClN6O2/c1-15-3-5-20(30-25-8-9-26-30)18(13-15)22(31)29-12-11-28(10-7-16(29)2)23-27-19-14-17(24)4-6-21(19)32-23/h3-6,8-9,13-14,16H,7,10-12H2,1-2H3/t16-/m1/s1 JYTNQNCOQXFQPK-MRXNPFEDSA-N 450.92100 450.15710 C[C@@H]1CCN(CCN1C(=O)c1cc(C)ccc1-n1nccn1)c1nc2cc(Cl)ccc2o1 CAS:1030377-33-3 Drug_Central:4881 KEGG:D10082 PMID:23372274 PMID:23692283 PMID:24368893 PMID:24488306 PMID:24550770 PMID:24680372 PMID:24757363 PMID:25167596 PMID:25197807 PMID:25227290 PMID:25231363 PMID:25291725 PMID:25299902 Reaxys:18339082 Wikipedia:Suvorexant [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone chebi_ontology BELSOMRA MK 4305 MK-4305 MK4305 CHEBI:82698 suvorexant A racemate comprising equimolar amounts of (R)- and (S)-paliperidone. Paliperidone is the primary active metabolite of the older antipsychotic risperidone and is used for treatment of schizophrenia. 0 C23H27FN4O3 426.48390 426.20672 CAS:144598-75-4 DrugBank:DB01267 HMDB:HMDB0015396 KEGG:D05339 PMID:23428785 PMID:24289141 PMID:24324228 PMID:24346811 PMID:24400982 PMID:24462396 PMID:24491033 PMID:24556260 PMID:24597755 PMID:24690136 PMID:24752928 PMID:24829608 PMID:24962437 PMID:25085446 PMID:25147315 PMID:25377151 Reaxys:8808385 Wikipedia:Paliperidone rac-3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one chebi_ontology (+-)-paliperidone (RS)-paliperidone 9-Hydroxyrisperidone 9-OH-risperidone 9-hydroxy-risperidone Invega R 76477 R-76477 RO76477 Ro-76477 paliperidone rac-paliperidone racemic paliperidone CHEBI:82978 paliperidone A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression. 0 C13H17ClN2O2 InChI=1S/C13H17ClN2O2/c14-12-3-1-11(2-4-12)13(17)15-5-6-16-7-9-18-10-8-16/h1-4H,5-10H2,(H,15,17) YHXISWVBGDMDLQ-UHFFFAOYSA-N 268.73900 268.09786 Clc1ccc(cc1)C(=O)NCCN1CCOCC1 CAS:71320-77-9 DrugBank:DB01171 Drug_Central:1825 HMDB:HMDB0015302 KEGG:D02561 LINCS:LSM-5247 PMID:23616181 PMID:24859491 PMID:24863864 PMID:25335956 Reaxys:530974 4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide chebi_ontology moclobemida moclobemide moclobemidum CHEBI:83531 moclobemide Any amino-acid that is not naturally encoded in the genetic code of any organism. Wikipedia:Non-proteinogenic_amino_acids chebi_ontology non-canonical amino acid non-canonical amino acids non-canonical amino-acid non-canonical amino-acids non-coded amino acid non-coded amino acids non-coded amino-acid non-coded amino-acids non-proteinogenic amino acids non-proteinogenic amino-acid non-proteinogenic amino-acids CHEBI:83820 non-proteinogenic amino acid Any phospho sugar that is the phosphate derivative of pentose. chebi_ontology pentose phosphates CHEBI:84055 pentose phosphate Carbohydrate derivatives resulting from the non-enzymatic glycosylation of proteins. They result in cells becoming stiffer and more prone to damage and premature aging. PMID:21116609 PMID:21659759 PMID:21909978 PMID:23129015 PMID:23404649 PMID:23745547 PMID:24173721 PMID:24370182 PMID:24624331 PMID:24771986 PMID:25172739 PMID:25438650 Wikipedia:Advanced_glycation_end-product chebi_ontology AGE AGEs advanced glycation end-products CHEBI:84123 advanced glycation end-product A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. 0 C20H24ClN3S InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 WIKYUJGCLQQFNW-UHFFFAOYSA-N 373.94300 373.13795 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 CHEBI:59073 Beilstein:48537 CAS:58-38-8 DrugBank:DB00433 Drug_Central:2274 HMDB:HMDB0014577 KEGG:C07403 KEGG:D00493 LINCS:LSM-2436 PMID:13808146 PMID:1650428 PMID:20825390 PMID:4891872 Patent:FR1167627 Patent:GB780193 Patent:US2902484 Reaxys:48537 Wikipedia:Prochlorperazine 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine Prochlorperazine chebi_ontology 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine 3-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine Prochlorperazin Prochlorpermazine Prochlorpromazine Procloperazine prochlorperazine prochlorperazinum proclorperazina CHEBI:8435 prochlorperazine A phenothiazine deriative in which the phenothiazine tricycle has a 3-(dimethylaminopropyl) group at the N-10 position. 0 C17H20N2S InChI=1S/C17H20N2S/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19/h3-6,8-11H,7,12-13H2,1-2H3 ZGUGWUXLJSTTMA-UHFFFAOYSA-N 284.42018 284.13472 CN(C)CCCN1c2ccccc2Sc2ccccc12 Beilstein:244925 CAS:58-40-2 DrugBank:DB00420 Drug_Central:2284 HMDB:HMDB0014564 KEGG:C07379 KEGG:D08430 LINCS:LSM-2137 PMID:1650428 PMID:18423639 PMID:19306624 PMID:20825390 Patent:US2519886 Reaxys:244925 Wikipedia:Promazine N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine Promazine chebi_ontology 10-(3-(Dimethylamino)propyl)phenothiazine N-(3-Dimethylaminopropyl)phenothiazine N-Dimethylamino-1-methylethyl thiodiphenylamine promazina promazine promazinum CHEBI:8459 promazine 0 C19H21N InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3 BWPIARFWQZKAIA-UHFFFAOYSA-N 263.37678 263.16740 CNCCCC1c2ccccc2C=Cc2ccccc12 Beilstein:2217411 CAS:438-60-8 DrugBank:DB00344 Drug_Central:2320 KEGG:C07408 KEGG:D08447 LINCS:LSM-2936 Wikipedia:Protriptyline 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine Protriptyline chebi_ontology 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene 7-(3-methylaminopropyl)-1,2:5,6-dibenzocycloheptatriene N-methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine N-methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine amimetilina CHEBI:8597 protriptyline A nitrotyrosine comprising tyrosine having a nitro group at the 3-position on the phenyl ring. 0 C9H10N2O5 InChI=1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14) FBTSQILOGYXGMD-UHFFFAOYSA-N 226.18610 226.05897 NC(Cc1ccc(O)c(c1)[N+]([O-])=O)C(O)=O CAS:3604-79-3 Reaxys:2219127 3-nitrotyrosine chebi_ontology CHEBI:86269 3-nitrotyrosine +1 C9H13N2O2 InChI=1S/C9H13N2O2/c1-10(2)9(12)13-8-5-4-6-11(3)7-8/h4-7H,1-3H3/q+1 RVOLLAQWKVFTGE-UHFFFAOYSA-N 181.212 181.09715 CN(C)C(=O)Oc1ccc[n+](C)c1 CAS:155-97-5 Drug_Central:2330 HMDB:HMDB0014685 KEGG:C07410 LINCS:LSM-5770 Pyridostigmine chebi_ontology pyridostigmine bromide pyridostigmine iodide CHEBI:8665 Pyridostigmine 0 C21H25N3O2S InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 383.50700 383.16675 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 CAS:111974-69-7 DrugBank:DB01224 Drug_Central:2337 KEGG:C07397 KEGG:D08456 LINCS:LSM-3543 Patent:EP240228 Patent:US4879288 Wikipedia:Quetiapine 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol Quetiapine chebi_ontology 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol quetiapina quetiapine quetiapinum CHEBI:8707 quetiapine A member of the class of isoquinolines that is (3S)-2-L-alanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid in which the alpha-amino group of the alanyl residue has been substituted by a 1-ethoxycarbonyl-4-phenylbutan-2-yl group (the all-S isomer). A prodrug for quinaprilat (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) used (generally as the hydrochloride salt) for the treatment of hypertension and congestive heart failure. 0 C25H30N2O5 InChI=1S/C25H30N2O5/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30)/t17-,21-,22-/m0/s1 JSDRRTOADPPCHY-HSQYWUDLSA-N 438.517 438.21547 C1C2=C(C[C@H](N1C([C@@H](N[C@H](C(OCC)=O)CCC=3C=CC=CC3)C)=O)C(O)=O)C=CC=C2 CAS:85441-61-8 DrugBank:DB00881 Drug_Central:2340 KEGG:C07398 KEGG:D03752 LINCS:LSM-3620 PMID:17404826 PMID:27165572 PMID:27169890 PMID:29980144 Patent:US4344949 Wikipedia:Quinapril (3S)-2-{(2S)-2-[(1S)-1-ethoxycarbonyl-3-phenylpropylamino]propanoyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (3S)-2-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid Quinapril chebi_ontology (3S)-2-{N-[(2S)-1-ethoxycarbonyl-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid quinapril quinaprilum CHEBI:8713 quinapril Any organooxygen compound whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties. PMID:1464741 PMID:15531285 PMID:20467214 PMID:25488134 PMID:25655639 PMID:25808421 PMID:25894795 PMID:26002574 Wikipedia:Statin chebi_ontology statins CHEBI:87631 statin A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. 0 C23H32N2O5 InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1 HDACQVRGBOVJII-JBDAPHQKSA-N 416.51060 416.23112 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H]2CCC[C@H]2C[C@H]1C(O)=O Beilstein:4214464 CAS:87333-19-5 DrugBank:DB00178 Drug_Central:2356 HMDB:HMDB0014324 KEGG:D00421 LINCS:LSM-5950 PMID:11095026 PMID:11575208 PMID:12076194 PMID:12768220 PMID:15110900 PMID:16144510 PMID:16734081 PMID:17004100 PMID:17192135 PMID:17496463 PMID:17903031 PMID:20122169 PMID:22799880 PMID:23557551 PMID:23713675 PMID:23747952 PMID:23842688 PMID:23842829 PMID:23951921 PMID:24048485 PMID:24090393 PMID:24191305 PMID:24397981 PMID:24435506 PMID:24452090 PMID:24509355 Reaxys:4214464 VSDB:1888 Wikipedia:Ramipril (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid Ramipril chebi_ontology (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid Altace (TN) Ramiprilum Tritace ramipril CHEBI:8774 ramipril A ketohexose monophosphate consisting of fructose having a phosphate group located at the 6-position. chebi_ontology CHEBI:88003 fructose 6-phosphate A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2. 0 C23H27FN4O2 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 410.48450 410.21180 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 Beilstein:4891881 CAS:106266-06-2 DrugBank:DB00734 Drug_Central:2389 HMDB:HMDB0005020 KEGG:D00426 LINCS:LSM-3193 PMID:11229618 PMID:11476125 PMID:14687852 PMID:14728058 PMID:15096074 PMID:17054229 PMID:18545060 PMID:18722468 PMID:19412457 PMID:20825390 PMID:23327578 Patent:EP196132 Patent:US4804663 Reaxys:4891881 Wikipedia:Risperidone 3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one risperidone chebi_ontology Risperdal Risperin Rispolept Rispolin Sequinan risperidona risperidone risperidonum CHEBI:8871 risperidone A carbamate ester obtained by formal condensation of the carboxy group of ethyl(methyl)carbamic acid with the phenolic OH group of 3-[(1S)-1-(dimethylamino)ethyl]phenol. A reversible cholinesterase inhibitor. 0 C14H22N2O2 InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 XSVMFMHYUFZWBK-NSHDSACASA-N 250.33670 250.16813 CCN(C)C(=O)Oc1cccc(c1)[C@H](C)N(C)C CAS:123441-03-2 DrugBank:DB00989 Drug_Central:2392 KEGG:C11766 KEGG:D03822 LINCS:LSM-5280 PMID:19032006 PMID:19370562 PMID:19392927 PMID:19619073 PMID:19893314 PMID:20070789 PMID:20370805 PMID:20865460 PMID:21131668 PMID:21246897 PMID:21977379 PMID:21996001 PMID:22009228 PMID:22010358 PMID:22044027 PMID:22054233 PMID:22068922 PMID:22087207 PMID:22163241 PMID:22163242 PMID:22163243 PMID:22173266 PMID:22195801 PMID:22224039 PMID:22230648 PMID:22230878 PMID:22290743 PMID:22362231 PMID:22409834 PMID:22451057 Patent:DE3805744 Patent:EP1980552 Patent:EP2233465 Patent:US2008255383 Patent:US2009298817 Patent:US5602176 Reaxys:7875788 Wikipedia:Rivastigmine 3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate chebi_ontology (S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate rivastigmine CHEBI:8874 rivastigmine A butenolide that is furan-2(5H)-one substituted by a phenyl group at position 3 and by a p-(methylsulfonyl)phenyl group at position 4. A selective cyclooxygenase 2 inhibitor, it was used from 1999 to 2004 for the treatment of ostoarthritis, but was withdrawn following concerns about an associated increased risk of heart attack and stroke. 0 C17H14O4S InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 314.35600 314.06128 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 Beilstein:8269007 CAS:162011-90-7 DrugBank:DB00533 Drug_Central:2397 KEGG:C07590 KEGG:D00568 LINCS:LSM-2482 PMID:10859630 PMID:11014111 PMID:12069696 PMID:16934051 PMID:20162413 PMID:28166217 Reaxys:8269007 Wikipedia:Rofecoxib 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one Rofecoxib chebi_ontology 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone Ceoxx Vioxx rofecoxib rofecoxibum CHEBI:8887 rofecoxib A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. 0 C17H17Cl2N InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 306.23000 305.07380 [H][C@]1(CC[C@H](NC)c2ccccc12)c1ccc(Cl)c(Cl)c1 Beilstein:5753709 CAS:79617-96-2 DrugBank:DB01104 Drug_Central:2436 HMDB:HMDB0005010 KEGG:C07246 KEGG:D02360 LINCS:LSM-3843 PDBeChem:SRE PMID:19502000 PMID:21823671 Patent:US4536518 Reaxys:5753709 Wikipedia:Sertraline (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine Sertraline chebi_ontology (+)-sertraline (1S,4S)-sertraline (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine CP 51974 cis-(+)-sertraline sertralina sertraline sertralinum CHEBI:9123 sertraline A member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug. 0 C25H38O5 InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1 RYMZZMVNJRMUDD-HGQWONQESA-N 418.56620 418.27192 CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 CHEBI:45577 Beilstein:4768037 CAS:79902-63-9 DrugBank:DB00641 Drug_Central:2445 HMDB:HMDB0005007 KEGG:D00434 LINCS:LSM-2492 PMID:11336576 PMID:12827636 PMID:14561068 PMID:14973129 PMID:18199328 PMID:18688862 PMID:18936176 Patent:EP33538 Patent:US4444784 Wikipedia:Simvastatin (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate Simvastatin chebi_ontology 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one MK-733 Simvastatina Simvastatine Simvastatinum Zocor simvastatin CHEBI:9150 simvastatin A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions. 0 C20H17FO3S InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9- MLKXDPUZXIRXEP-MFOYZWKCSA-N 356.41158 356.08824 CC1=C(CC(O)=O)c2cc(F)ccc2C\1=C/c1ccc(cc1)S(C)=O Beilstein:2951842 CAS:38194-50-2 DrugBank:DB00605 Drug_Central:2534 HMDB:HMDB0014743 KEGG:C01531 KEGG:D00120 PDBeChem:SUZ PMID:11569947 PMID:11927004 PMID:12406542 PMID:15020200 PMID:15123337 PMID:19884509 PMID:23689354 PMID:23804703 Patent:DE2039426 Patent:US3654349 Reaxys:2951842 Wikipedia:Sulindac Sulindac {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid chebi_ontology (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid Clinoril Sulindacum cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid sulindac sulindaco CHEBI:9352 sulindac An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group. 0 C14H12O3S InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17) MDKGKXOCJGEUJW-UHFFFAOYSA-N 260.30800 260.05072 CC(C(O)=O)c1ccc(cc1)C(=O)c1cccs1 CHEBI:193117 Beilstein:1430606 CAS:40828-46-4 DrugBank:DB00870 Drug_Central:2546 KEGG:C07320 KEGG:D00452 LINCS:LSM-4406 PMID:11195850 PMID:11409928 PMID:14570769 PMID:14664336 PMID:27559371 PMID:7918773 PMID:8058269 Patent:DE2353357 Patent:US4035376 Reaxys:1430606 Wikipedia:Suprofen 2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid chebi_ontology (+-)-2-(p-(2-thenoyl)phenyl)propionic acid 2-(4-(2-Thenoyl)phenyl)propionsaeure 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid 4-(2-Thenoyl)hydratropsaeure PROFENAL SUTOPROFEN alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid p-2-thenoylhydratropic acid suprofen suprofene suprofenum CHEBI:9362 suprofen 0 C16H13ClN2O2 InChI=1S/C16H13ClN2O2/c1-19-13-8-7-11(17)9-12(13)14(18-15(20)16(19)21)10-5-3-2-4-6-10/h2-9,15,20H,1H3 SEQDDYPDSLOBDC-UHFFFAOYSA-N 300.740 300.06656 CN1c2ccc(Cl)cc2C(=NC(O)C1=O)c1ccccc1 CAS:846-50-4 Drug_Central:2585 HMDB:HMDB0014376 KEGG:C07125 KEGG:D00370 Temazepam chebi_ontology (RS)-Temazepam Restoril (TN) levanxene levanxol CHEBI:9435 Temazepam A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position. 0 C21H26N2S2 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 370.57500 370.15374 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 Beilstein:94457 CAS:50-52-2 DrugBank:DB00679 Drug_Central:2637 HMDB:HMDB0014817 KEGG:D00373 LINCS:LSM-1863 PMID:10796547 PMID:11686961 PMID:1650428 PMID:17764469 PMID:17876580 PMID:19747949 PMID:20825390 PMID:26956010 PMID:27023487 PMID:27068340 PMID:9352572 Reaxys:94457 Wikipedia:Thioridazine 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine chebi_ontology 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine Mallorol Malloryl Meleril Mellaril Mellaril-S Mellerets Mellerette Melleril Orsanil Sonapax Thioridazin thioridazine thioridazinum tioridazina CHEBI:9566 thioridazine A heterobicylic compound that is (2S,3aR,7aS)-1-[(2S)-2-aminopropanoyl]octahydro-1H-indole-2-carboxylic acid in which the hydrogen of the amino group is substituted by a (2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl group. It is a angiotensin-converting enzyme inhibitor and a prodrug used for the treatment of hypertension. 0 C24H34N2O5 InChI=1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1 VXFJYXUZANRPDJ-WTNASJBWSA-N 430.545 430.24677 [H][C@@]12C[C@H](N(C(=O)[C@H](C)N[C@@H](CCC3=CC=CC=C3)C(=O)OCC)[C@@]1([H])CCCC2)C(O)=O CAS:87679-37-6 Chemspider:4588590 DrugBank:DB00519 Drug_Central:2712 HMDB:HMDB0014660 KEGG:D00383 PMID:1648489 PMID:19337528 PMID:22247843 PMID:23784370 PMID:24835355 PMID:25802524 PMID:25864194 PMID:26915813 PMID:27215243 PMID:29319234 PMID:32964020 PMID:33660934 PMID:3383998 PMID:34172790 PMID:8515499 PMID:8515500 PMID:8515501 PMID:8515502 PMID:8515504 PMID:9770740 Patent:KR20080046630 Patent:WO2006014916 Reaxys:8655766 Wikipedia:Trandolapril (2S,3aR,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid chebi_ontology (2S,3aR,7aS)-1-((S)-N-((S)-1-carboxy-3-phenylpropyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester Gopten Mavik Odrik RU 44570 RU-44570 RU44570 trandolapril trandolaprilum CHEBI:9649 trandolapril A racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine). CHEBI:39677 CHEBI:46075 CAS:155-09-9 DrugBank:DB00752 HMDB:HMDB0014890 KEGG:C07155 KEGG:D08625 MetaCyc:CPD-17677 PDBeChem:TPA PMID:11181487 PMID:12495786 PMID:13948833 PMID:15049511 PMID:18974922 PMID:20148560 PMID:26257022 PMID:26302763 PMID:26348077 PMID:26479223 PMID:26748182 PMID:26917855 PMID:7236991 PMID:7511710 PMID:7531152 PMID:7675827 PMID:7776254 PMID:8831798 PMID:9049597 PMID:9829163 Reaxys:3195803 Wikipedia:Tranylcypromine Tranylcypromine rac-(1R,2S)-2-phenylcyclopropan-1-amine chebi_ontology (+-)-trans-2-phenylcyclopropylamine (1R*,2S*)-2-phenylcyclopropan-1-amine DL-tranylcypromine Racemic Tranylcypromine SKF 385 SKF Trans-385 Transamine Tranylcypromin tranilcipromina trans-2-phenylcyclopropylamine trans-DL-2-Phenylcyclopropylamine tranylcypromine tranylcyprominum CHEBI:9652 tranylcypromine An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group. 0 C19H22ClN5O InChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2 PHLBKPHSAVXXEF-UHFFFAOYSA-N 371.86400 371.15129 Clc1cccc(c1)N1CCN(CCCn2nc3ccccn3c2=O)CC1 Beilstein:628010 CAS:19794-93-5 DrugBank:DB00656 Drug_Central:2717 KEGG:C07156 KEGG:D08626 LINCS:LSM-3580 Patent:US3381009 Wikipedia:Trazodone 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one Trazodone chebi_ontology 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one trazodona trazodone trazodonum CHEBI:9654 trazodone A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(dimethylamino)propyl group at the N-10 position. 0 C18H19F3N2S InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3 XSCGXQMFQXDFCW-UHFFFAOYSA-N 352.41700 352.12210 CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F Beilstein:335308 CAS:146-54-3 DrugBank:DB00508 Drug_Central:2742 HMDB:HMDB0014650 KEGG:D00390 LINCS:LSM-3421 PMID:1650428 PMID:24959397 Patent:GB813861 Reaxys:335308 Wikipedia:Triflupromazine N,N-dimethyl-3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propan-1-amine chebi_ontology 10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine 2-(Trifluoromethyl)promazine 2-Trifluoromethyl-10-(gamma-dimethylaminopropyl)phenothiazine trifluopromazine triflupromazina triflupromazine triflupromazinum CHEBI:9711 triflupromazine A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant. 0 C20H26N2 InChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3 ZSCDBOWYZJWBIY-UHFFFAOYSA-N 294.43392 294.20960 CC(CN(C)C)CN1c2ccccc2CCc2ccccc12 Beilstein:1321466 CAS:739-71-9 DrugBank:DB00726 Drug_Central:2758 HMDB:HMDB0014864 KEGG:D00394 LINCS:LSM-1371 PMID:22642681 PMID:25178259 Patent:CN103893187 Reaxys:1321466 Wikipedia:Trimipramine 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-amine Trimipramine chebi_ontology 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine 5-(gamma-dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine RP-7162 Sapilent Trimeprimine beta-methylimipramine trimeproprimine CHEBI:9738 trimipramine A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-methoxyphenyl group. 0 C17H27NO2 InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3 PNVNVHUZROJLTJ-UHFFFAOYSA-N 277.40182 277.20418 COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Beilstein:4234848 CAS:93413-69-5 DrugBank:DB00285 Drug_Central:2813 HMDB:HMDB0005016 KEGG:C07187 KEGG:D08670 LINCS:LSM-1616 PMID:11098420 PMID:12409680 PMID:18321472 Reaxys:4234848 Wikipedia:Venlafaxine 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol Venlafaxine chebi_ontology Elafax venlafaxina venlafaxine venlafaxinum CHEBI:9943 venlafaxine LCL-2000 LCL-2000 SH-SY5Y SH-SY5Y https://www.atcc.org/en/Products/Cells_and_Microorganisms/By_Tissue/Bone_Marrow/CRL-2266.aspx https://www.atcc.org/en/Products/Cells_and_Microorganisms/By_Tissue/Bone_Marrow/CRL-2266.aspx SHSY5Y SHSY5Y SH-SY5Y cell SH-SY5Y cell SH-SY5Y 细胞 ATCC: CRL-2266 ATCC: CRL-2266 Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors. BTO:0002881 CALOHA:TS-2360 FMA:86684 NSC neural stem cell cell neuronal stem cell A neurectoderm derived cell that lines the neural lumen. BTO:0001724 FMA:70550 ependymocyte cell ependymal cell A leukocyte with abundant granules in the cytoplasm. BTO:0000539 BTO:0001026 CALOHA:TS-0422 FMA:62854 granular leucocyte granular leukocyte polymorphonuclear leukocyte cell granulocyte Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. BTO:0003811 FBbt:00005125 FMA:67313 WBbt:0005113 cell interneuron cell adrenergic neuron cell CNS neuron (sensu Vertebrata) cell basket cell BTO:0003393 cell granule cell The output neuron of the cerebellar cortex. BTO:0001011 CALOHA:TS-0845 FMA:67969 Purkinje neuron Purkinje's cell cerebellar Purkinje cell cerebellum Purkinje cell cell Purkinje cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. BTO:0002606 CALOHA:TS-0415 FMA:54536 neuroglial cell cell neuroglia glial cell A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. BTO:0000099 CALOHA:TS-0060 FMA:54537 astrocytic glia cell Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive. astrocyte A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. BTO:0000962 CALOHA:TS-0709 FMA:54540 OLs cell oligodendroglia Oligodendrocytes are reportedly MDP-positive and CD4-negative. oligodendrocyte A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. brain macrophage BTO:0000078 BTO:0000962 FMA:54539 FMA:54540 brain-resident macrophage hortega cells microglia microgliocyte cell MF.microglia.CNS Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive. microglial cell A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. BTO:0000801 CALOHA:TS-0587 FMA:63261 FMA:83585 histiocyte cell Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. macrophage cell eukaryotic cell The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. BTO:0000938 CALOHA:TS-0683 FBbt:00005106 FMA:54527 VHOG:0001483 WBbt:0003679 nerve cell cell These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. neuron neuron A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. BTO:0000775 CALOHA:TS-0583 FMA:62863 VHOG:0001535 cell Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) lymphocyte Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. BTO:0000876 CALOHA:TS-0638 FMA:62864 cell Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. monocyte Pyramidal neurons have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala. BTO:0003102 FMA:67310 FMA:86775 NIFSTD:sao862606388 projection neuron pyramidal cell pyramidal neuron cell pyramidal neuron A neuron that uses GABA as a vesicular neurotransmitter FMA:84788 WBbt:0005190 GABA-ergic neuron cell GABAergic neuron An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. CL:0000184 BTO:0002441 FMA:63174 ARC adventitial reticular cell cell of Rouget pericyte pericyte of Rouget cell adventitial cell Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A. pericyte cell WBbt:0006829 cell glutamatergic neuron A neuron that releases dopamine as a neurotransmitter. BTO:0004032 FMA:84787 WBbt:0006746 dopaminergic cell cell dopaminergic neuron An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. BTO:0000751 CALOHA:TS-0549 FMA:62852 immune cell leucocyte white blood cell cell leukocyte Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive. polymorphonuclear leucocyte polymorphonuclear leukocyte BTO:0000129 CALOHA:TS-0073 FMA:62862 basophilic leucocyte basophilic leukocyte cell Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive. basophil Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. polymorphonuclear leucocyte polymorphonuclear leukocyte BTO:0000399 CALOHA:TS-0279 FMA:62861 eosinocyte eosinophilic granulocyte eosinophilic leucocyte eosinophilic leukocyte cell Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. eosinophil Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. PMN poly polymorphonuclear leucocyte polymorphonuclear leukocyte polymorphonuclear neutrophil polynuclear neutrophilic leucocyte polynuclear neutrophilic leukocyte BTO:0000130 CALOHA:TS-0688 FMA:62860 neutrocyte neutrophil leucocyte neutrophil leukocyte neutrophilic leucocyte neutrophilic leukocyte cell neutrophil A neuron that releases serotonin as a neurotransmitter. CL:0000403 FBbt:00005133 WBbt:0006837 5-HT neuron 5-hydroxytryptamine neuron cell serotinergic neuron serotonergic neuron A cell that is part of the nervous system. tmeehan 2010-09-15T01:34:57Z CALOHA:TS-2040 FMA:70333 cell neural cell A glial cell that ensheathes axons of neuron in the peripheral nervous system and are necessary for their maintainance and function. tmeehan 2011-03-02T01:19:27Z BTO:0001220 CALOHA:TS-0898 cell Schwann cell A neuron of the hippocampus. tmeehan 2011-03-06T07:31:49Z cell hippocampal neuron The inhibitory projection neurons located in the striatum that integrate glutamatergic signals arising from the cerebral cortex and thalamus. BTO:0004778 striatal medium spiny neuron cl medium-sized densely spiny neuron medium spiny neuron Any neuron that is part of a central nervous system. TermGenie 2014-06-25T01:17:43Z cell CL:2000029 central nervous system neuron A quantitative or qualitative value which is the result of an act of assessing a morphological or physiological state or property in a single individual or sample or a group of individuals or samples, based on direct observation or experimental manipulation. clinical measurement Any value resulting from the quantification of a morphological or physiological parameter pertaining to the heart and/or blood vessels. cardiovascular measurement A quantification of a parameter of the chemical composition of blood. blood molecular composition measurement blood chemistry measurement The number of red blood cells in a specified volume of blood most commonly 1 cubic millimeter (i.e. 1 microliter) of peripheral venous blood. erythrocyte count red blood cell count The number of white blood cells in a specified volume of blood. leukocyte count white corpuscle count white blood cell count A measurement of the blood, it's contents, cells or other factors contained within the blood. blood measurement A value resulting from the quantification of a morphological or physiological parameter of blood cells, i.e. cells native to the circulation, including those of erythroid, lymphoid, myeloid and monocytic lineages. A cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning. blood cell measurement A measurement relating body weight to height in an organism; typically calculated as the weight of an individual divided by the height of that individual squared. For quadrupeds, the square of body height is often replaced by the square of body length. BMI body mass index (BMI) mshimoyama 2010-06-17T10:30:36Z Any quantification of a morphological or physiological parameter of one or more cells. A cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning. cell measurement mshimoyama 2010-08-04T10:37:40Z The count of the rhythmic contractions and expansions of an artery due to the surge of blood from the beat of the heart. pulse JSmith 2013-01-07T16:14:04Z Any measurement of the fluid contained within the ventricles of the brain, the subarachnoid space, and the central canal of the spinal cord. cerebrospinal fluid measurement The party or parties involved in the clinical trial who are prevented from having knowledge of the interventions assigned to individual participants. blinding masking masking design http://www.icmje.org/recommendations/ http://www.who.int/ictrp/network/trds/en/index.html a study design in which the subjects and the investigators are permitted to know which subject is receiving which treatment open blind open label open blinded design The quality of a clinical trial that studies a drug or biological product. The phase is based on the study's objective, the number of participants, and other characteristics. According to USA FDA, there are five phases: Early Phase 1 (formerly listed as Phase 0), Phase 1, Phase 2, Phase 3, and Phase 4. Leon Li, Asiyah Lin, Oliver He clinical trial stage https://www.clinicaltrials.gov/ct2/help/glossary/phase phase clinical trial phase https://www.who.int/ictrp/network/trds/en/ A clinical trial phase that represents the first-in-man trial, which tests within a small group of people (typically 20-80) to evaluate safety, determine safe dosage ranges, and begin to identify side effects. A drug's side effects could be subtle or long term, or may only happen with a few people, so phase 1 trials are not expected to identify all side effects. Leon Li, Asiyah Lin, Oliver He Phase 1 Phase I http://purl.obolibrary.org/obo/NCIT_C15600 https://en.wikipedia.org/wiki/Clinical_trial C0920321 C15600 clinical trial phase 1 A clinical trial phase that is designed to study a biomedical or behavioral intervention in a larger group of people (several hundred), to evaluate the drug's effectiveness for a particular indication in patients with the disease or condition under study, and to determine the common short-term side effects and risks associated with the intervention. [def-source: NCI] Leon Li, Asiyah Lin, Oliver He Phase II http://purl.obolibrary.org/obo/NCIT_C15601 https://en.wikipedia.org/wiki/Clinical_trial C0282460 C15601 clinical trial phase 2 A clinical trial phase that is designed to investigate the efficacy of the biomedical or behavioral intervention in large groups of human subjects (from several hundred to several thousand), to confirm efficacy, to monitor adverse reactions to the new medication or treatment regimen with respect to long-term use and by comparing the intervention to other standard or experimental interventions as well as to a placebo. [def-source: NCI] Leon Li, Asiyah Lin, Oliver He Phase III http://purl.obolibrary.org/obo/NCIT_C15602 https://en.wikipedia.org/wiki/Clinical_trial C0282461 C15602 clinical trial phase 3 A clinical trial phase that is designed for a randomized, controlled trial to evaluate the long-term safety and efficacy of a drug for a given indication. Often they are designed to study side effects that may have become apparent after the phase III study was completed. [def-source: NCI] Leon Li, Asiyah Lin, Oliver He Phase IV https://en.wikipedia.org/wiki/Clinical_trial C0282462 C15603 clinical trial phase 4 a clinical trial is a medical interventional study where participants are assigned prospectively to an intervention or interventions according to a protocol to evaluate the safety and efficacy of the intervention(s) on biomedical or other health related outcomes. The Interventions include but are not restricted to drugs, cells and other biological products, surgical procedures, radiologic procedures, devices, behavioral treatments, process-of-care changes, preventive care, etc. Oliver He, Asiyah Yu Lin, Qingliang Li interventional trial https://clinicaltrials.gov/ct2/search/map https://en.wikipedia.org/wiki/Clinical_trial https://prsinfo.clinicaltrials.gov/definitions.html https://www.who.int/ictrp/en/ clinical trial A disease that involving errors in metabolic processes of building or degradation of molecules. ICD10CM:E88.9 ICD9CM:277.9 MESH:D008659 NCI:C3235 SNOMEDCT_US_2020_09_01:75934005 UMLS_CUI:C0025517 metabolic disease disease_ontology DOID:0014667 disease of metabolism A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions. infectious disease DOID:10115 DOID:11078 DOID:1304 DOID:1321 DOID:2040 DOID:2288 DOID:3099 DOID:4120 DOID:4620 DOID:5256 DOID:945 DOID:95 DOID:9532 DOID:9696 ICD9CM:079.0 UMLS_CUI:C0001485 infectious disease disease_ontology DOID:0050117 DO:wk disease by infectious agent A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development. disease_ontology DOID:0060037 developmental disorder of mental health A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination. disease_ontology DOID:0060038 specific developmental disorder A developmental disorder of mental health that refers to a group of five disorders characterized by impairments in socialization and communication, as well as restricted interests and repetitive behaviors. DOID:1208 ICD9CM:299.80 UMLS_CUI:C0154451 pervasive development disorder disease_ontology DOID:0060040 pervasive developmental disorder A disease of mental health that involves the impairment in normal sexual functioning. disease_ontology DOID:0060043 sexual disorder A cognitive disorder that is characterized by objective impairment in cognition with minimal impairment of their capacity to undertake the instrumental activities of daily living. disease_ontology DOID:0080832 mild cognitive impairment A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. EFO:0000249 GARD:10254 ICD10CM:G30 ICD9CM:331.0 KEGG:05010 MESH:D000544 NCI:C2866 SNOMEDCT_US_2020_03_01:73768007 SNOMEDCT_US_2020_09_01:73768007 UMLS_CUI:C0002395 Alzheimer disease Alzheimers dementia disease_ontology DOID:10652 Xref MGI. OMIM mapping confirmed by DO. [SN]. Alzheimer's disease An artery disease characterized by chronic elevated blood pressure in the arteries. EFO:0000537 ICD10CM:I10 ICD9CM:401-405.99 MESH:D006973 NCI:C3117 SNOMEDCT_US_2020_09_01:38341003 UMLS_CUI:C0020538 HTN High blood pressure hyperpiesia vascular hypertensive disorder disease_ontology hypertensive disease DOID:10763 hypertension A dissociative disorder that involves the simultaneous display of multiple distinct identities or personalities. ICD10CM:F44.81 ICD9CM:300.14 ICD9CM_2006:300.14 MESH:D009105 NCI:C94330 SNOMEDCT_US_2018_03_01:31611000 UMLS_CUI:C0026773 Dissociative identity disorder disease_ontology DOID:10934 multiple personality disorder A cardiovascular system disease that involves the heart. ICD10CM:I51.9 ICD9CM:429.9 MESH:D006331 NCI:C3079 SNOMEDCT_US_2020_09_01:194707003 UMLS_CUI:C0018799 disease_ontology DOID:114 heart disease GARD:7392 ICD10CM:G31.01 ICD9CM:331.11 MESH:D020774 NCI:C85008 OMIM:172700 SNOMEDCT_US_2020_03_01:154998003 UMLS_CUI:C0236642 Dementia in Pick's disease LOBAR ATROPHY OF BRAIN PICK DISEASE OF BRAIN Pick disease disease_ontology DOID:11870 OMIM mapping confirmed by DO. [SN]. Pick's disease MESH:D020774 A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities. GARD:3243 ICD10CM:G31.83 ICD9CM:331.82 MESH:D020961 NCI:C84826 OMIM:127750 SNOMEDCT_US_2020_09_01:192808003 UMLS_CUI:C0752347 Dementia with Lewy bodies Diffuse Lewy body disease Lewy body disease Senile dementia of the Lewy body type disease_ontology DOID:12217 OMIM mapping confirmed by DO. [SN]. Lewy body dementia A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities. GARD:6677 ICD10CM:G10 ICD9CM:333.4 KEGG:05016 MESH:D006816 NCI:C82342 OMIM:143100 SNOMEDCT_US_2020_03_01:155006000 SNOMEDCT_US_2020_09_01:155006000 UMLS_CUI:C0020179 HD Huntington disease Huntington's chorea disease_ontology DOID:12858 Huntington's disease A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. DOID:73 ICD9CM:429.2 MESH:D002318 NCI:C2931 SNOMEDCT_US_2020_09_01:266275004 UMLS_CUI:C0007222 disease of subdivision of hemolymphoid system disease_ontology DOID:1287 cardiovascular system disease A central nervous system disease that results in the progressive deterioration of function or structure of neurons. DOID:4874 ICD10CM:G31.9 MESH:D019636 NCI:C27090 SNOMEDCT_US_2020_03_01:362975008 SNOMEDCT_US_2020_09_01:362975008 UMLS_CUI:C0524851 UMLS_CUI:C1285162 Neurodegenerative disease degenerative disease disease_ontology DOID:1289 neurodegenerative disease A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior. ICD9CM:290.8 MESH:D003704 UMLS_CUI:C0154319 disease_ontology DOID:1307 dementia A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions. EFO:0002508 GARD:10251 ICD10CM:G20 ICD9CM:332 KEGG:05012 MESH:D010300 NCI:C26845 OMIM:PS168600 ORDO:2828 SNOMEDCT_US_2020_09_01:49049000 UMLS_CUI:C0030567 Parkinson disease paralysis agitans disease_ontology DOID:14330 Xref MGI. OMIM mapping confirmed by DO. [SN]. Parkinson's disease A thyroid gland disease which involves an underproduction of thyroid hormone. DOID:11630 EFO:0004705 ICD10CM:E03.9 ICD9CM:244.9 MESH:D007037 NCI:C26800 SNOMEDCT_US_2020_09_01:267465007 UMLS_CUI:C0020676 Thyroid deficiency Thyroid insufficiency disease_ontology DOID:1459 hypothyroidism A disease that involves a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which are not a part of normal development or culture. ICD10CM:F99 ICD10CM:F99-F99 MESH:D001523 NCI:C2893 SNOMEDCT_US_2018_03_01:74732009 SNOMEDCT_US_2020_09_01:74732009 UMLS_CUI:C0004936 disease_ontology DOID:150 disease of mental health A disease of mental health that involve long-term patterns of thoughts and behaviors that cause serious problems with relationships and work. ICD9CM:301.8 ICD9CM:301.89 UMLS_CUI:C0029707 character disorder disease_ontology DOID:1510 personality disorder A disease of mental health that affects cognitive functions including memory processing, perception and problem solving. ICD10CM:F09 MESH:D019965 NCI2004_11_17:C34870 NCI:C34870 UMLS_CUI:C0029227 cognitive disease disease_ontology Organic Mental disorder Organic Mental disorder DOID:1561 cognitive disorder A disease of anatomical entity that occurs in the muscular and/or skeletal system. MESH:D009140 NCI:C107377 SNOMEDCT_US_2018_03_01:928000 UMLS_CUI:C0026857 disease_ontology DOID:17 musculoskeletal system disease A cognitive disorder that involves an excessive, irrational dread of everyday situations. DOID:12884 ICD10CM:F41.9 MESH:D001008 NCI:C2878 OMIM:607834 SNOMEDCT_US_2018_03_01:65673007 UMLS_CUI:C0003469 anxiety anxiety state disease_ontology DOID:2030 anxiety disorder A disease characterized by a group of signs and symptoms that occur together and characterize a particular abnormality. MESH:D013577 NCI:C28193 SNOMEDCT_US_2018_03_01:64572001 SNOMEDCT_US_2020_09_01:64572001 UMLS_CUI:C0039082 disease_ontology DOID:225 syndrome A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality. EFO:0000677 ICD9CM:298.8 UMLS_CUI:C0029516 mental or behavioural disorder disease_ontology DOID:2468 psychotic disorder A substance-related disorder that involves a maladaptive pattern of substance use leading to significant impairment in functioning. MESH:D019966 NCI:C16522 SNOMEDCT_US_2020_09_01:26416006 UMLS_CUI:C0013146 disease_ontology DOID:302 substance abuse A disease of mental health involving the abuse or dependence on a substance that is ingested in order to produce a high, alter one's senses, or otherwise affect functioning. MESH:D019966 NCI:C92203 UMLS_CUI:C0236969 disease_ontology DOID:303 substance-related disorder A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system. ICD10CM:G96.9 MESH:D002493 NCI:C2934 SNOMEDCT_US_2020_03_01:267144009 SNOMEDCT_US_2020_09_01:267144009 UMLS_CUI:C0007682 disease_ontology DOID:331 central nervous system disease A cognitive disorder that involves a disturbance in mood as the predominant underlying feature. EFO:0004247 ICD10CM:F30-F39 ICD10CM:F39 MESH:D019964 NCI:C92200 SNOMEDCT_US_2018_03_01:46206005 SNOMEDCT_US_2018_03_01:74421008 UMLS_CUI:C0525045 episodic mood disorder disease_ontology DOID:3324 Updating outdated UMLS CUI. mood disorder A stomach disease that is an inflammation of the lining of the stomach. DOID:4032 DOID:8697 DOID:8845 DOID:9190 ICD10CM:K29.7 MESH:D005756 NCI:C26780 SNOMEDCT_US_2020_09_01:155711008 UMLS_CUI:C0017152 Erosive Gastritis Erosive gastropathy acute gastric mucosal erosion disease_ontology DOID:4029 gastritis A disease of mental health that involves physical symptoms suggesting a physical illness where the biological or medical cause of the symptoms is indeterminate. DOID:10133 DOID:144 CSP2005:2482-7019 ICD10CM:F45 ICD10CM:F45.0 ICD10CM:F45.9 ICD9CM:300.8 ICD9CM:300.81 MESH:D013001 NCI:C34956 SNOMEDCT_US_2018_03_01:31297008 SNOMEDCT_US_2018_03_01:60368009 SNOMEDCT_US_2018_03_01:9514005 UMLS_CUI:C0037650 UMLS_CUI:C0520482 physiological malfunction arising from mental factor psychophysiologic disorder psychosomatic disorder disease_ontology DOID:4737 somatoform disorder DOID:11510 GARD:7079 MESH:D012791 MESH:D019578 NCI:C84909 SNOMEDCT_US_2020_09_01:16576004 SNOMEDCT_US_2020_09_01:230297002 UMLS_CUI:C0037019 UMLS_CUI:C0393571 Multiple system atrophy Shy-Drager syndrome disease_ontology DOID:4752 OMIM mapping confirmed by DO. [LS]. multiple system atrophy A disease of mental health that involves disruption of sleep patterns. DOID:9028 ICD9CM:307.4 UMLS_CUI:C0154564 Non-organic sleep disorder disease_ontology DOID:535 sleep disorder A disease that has_material_basis_in genetic variations in the human genome. MESH:D030342 NCI:C3101 SNOMEDCT_US_2018_03_01:32895009 UMLS_CUI:C0019247 disease_ontology DOID:630 genetic disease A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain. MESH:D024801 UMLS_CUI:C0949664 disease_ontology DOID:680 tauopathy A disease that manifests in a defined anatomical structure. DOID:1 DOID:2 DOID:5 DOID:71 DOID:72 DOID:8 disease_ontology DOID:7 disease of anatomical entity A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system. ICD10CM:G00-G99 ICD10CM:G98 ICD10CM:G98.8 ICD9CM:349.9 MESH:D009422 NCI:C26835 SNOMEDCT_US_2020_03_01:155262005 UMLS_CUI:C0027765 disease_ontology DOID:863 nervous system disease A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain. DOID:13915 ICD10CM:F01 ICD9CM:290.4 MESH:D015140 MESH:D015161 NCI:C34522 NCI:C34525 SNOMEDCT_US_2020_09_01:192165000 SNOMEDCT_US_2020_09_01:56267009 UMLS_CUI:C0011263 UMLS_CUI:C0011269 Multi Infarct Dementia multifocal dementia disease_ontology DOID:8725 vascular dementia An amyloidosis where amyloid protein progressively deposits in cerebral blood vessel walls with subsequent degenerative vascular changes that usually result in spontaneous cerebral hemorrhage, ischemic lesions and progressive dementia. MESH:D028243 ORDO:85458 SNOMEDCT_US_2020_09_01:45639009 UMLS_CUI:C0268393 UMLS_CUI:C1510489 UMLS_CUI:C1527338 UMLS_CUI:C1956349 Cerebral Hemorrhage, Hereditary, with Amyloidosis Hereditary Cerebral Hemorrhage with Amyloidosis disease_ontology DOID:9246 Xref MGI. OMIM mapping confirmed by DO. [SN]. cerebral amyloid angiopathy A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language. GARD:8436 MESH:C563003 OMIM:600274 ORDO:282 SNOMEDCT_US_2020_09_01:42369001 UMLS_CUI:C0520716 Wilhemsen-Lynch disease frontotemporal lobar degeneration multiple system tauopathy with presenile dementia pallidopontonigral degeneration disease_ontology DOID:9255 Xref MGI. OMIM mapping confirmed by DO. [SN]. frontotemporal dementia MESH:D057180 A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. EFO:0001360 ICD10CM:E11 KEGG:04930 MESH:D003924 NCI:C26747 OMIM:125853 OMIM:601283 OMIM:601407 OMIM:603694 OMIM:608036 SNOMEDCT_US_2020_09_01:44054006 UMLS_CUI:C0011860 NIDDM insulin resistance non-insulin-dependent diabetes mellitus type 2 diabetes type II diabetes mellitus disease_ontology DOID:9352 Xref MGI. OMIM mapping confirmed by DO. [SN]. type 2 diabetes mellitus An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness. EFO:0001073 ICD10CM:E66.9 ICD9CM:278.00 MESH:D009765 NCI:C159658 OMIM:601665 SNOMEDCT_US_2020_09_01:5476005 UMLS_CUI:C0028754 disease_ontology DOID:9970 OMIM mapping confirmed by DO. [SN]. obesity 6011 Isocarboxazid 35350 Remoxipride 8375 placebo 6066 Isoxsuprine 24246 epigallocatechin gallate 318 Adenosine Triphosphate 8302 Phytic Acid 1541246 Glucose-6-Phosphate anatomical_structure EMAPA:25765 mouse Flow cytometry is a technique. A technique is a planned process used to accomplish a specific activity or task. PERSON: Melissa Haendel http://en.wikipedia.org/wiki/Technique Protocol is added to eagle-i temporarily until a relationship between the informatio entity "protocol" and these planned processes is created. This class refers to the axtual process not the document technique human study A clinical trial. Research project that uses or collects measurements or assessments about humans. PERSON: Melissa Haendel OCRe This should be imported from OCRE- but they currently have no generic human study type. Def is modified. human study epidemiological study A study of the populations and demographic of the avian flu. A human study of diseases in populations of humans or other animals, specifically how, when and where they occur. Epidemiological studies can never prove causation, epidemiological evidence can only show that this risk factor is correlated with a higher incidence of disease in the population exposed to that risk factor. The higher the correlation the more certain the association, but it cannot prove the causation. PERSON: Karen Corday http://pmep.cce.cornell.edu/profiles/extoxnet/TIB/epidemiology.html epidemiological study single blinded study An interventional study in which the person collecting the data knows whether the subjects are in the control or experimental groups but the subjects do not. PERSON: Nicole Vasilevsky http://medical-dictionary.thefreedictionary.com/single-blind+study single blinded study double blinded study An interventional study in which neither the subjects of the experiment nor the persons administering the experiment know the critical aspects of the experiment; a double-blind procedure is used to guard against both experimenter bias and placebo effects. PERSON: Nicole Vasilevsky http://www.thefreedictionary.com/double-blind+study double blinded study psychological and behavioral intervention Psychological or behavior intervention is a combination of program elements, strategies, or modalities designed to influence psychological or behavioral processes or outcomes. PERSON: Matthew Brush PERSON: Melanie Wilson psychological and behavioral intervention GFP expressing cells can be visualized by in vivo bioluminescence imaging. An image acquisition instrument that is designed for non-invasive in vivo use, to detect bioluminescence, which is based on the expression of luciferase, the light-emitting enzyme of the firefly Photinus pyralis. After the administration of the substrate luciferin, an ATP- and O2-dependent photochemical reaction occurs, resulting in the release of photons by living cells containing luciferase. This photon emission can be detected by a cooled charge-coupled device (CCD) camera, minutes after the administration of the substrate. PERSON: Nicole Vasilevsky Contag et al (1997) Photochem Photobiol 66: 523–531 in vivo bioluminescence imaging system PCR. An assay that generates data about the presence, abundance, structure, function, or activity of biological molecules, or a process that occurs at a molecular level of granularity. PERSON: Nicole Vasilevsky PERSON: Matthew Brush molecular assay A spinal tap may be performed to determine if a patient has a neurological disorder. A technique used to collect cerebrospinal fluid (CSF) from an organism, which involves inserting a needle between the third and fourth lumbar vertebrae in the back and extracting a sample of fluid. PERSON: Nicole Vasilevsky CSF collection Cerebrospinal fluid collection Spinal tap http://www.weissandnewberrymds.com/services.htm cerebro-spinal tap Phenotype characterization of a transgenic mouse. An assay that generates data about the physical characteristics, physological functions, or behavior of organisms or viruses. PERSON: Nicole Vasilevsky PERSON: Matthew Brush organismal assay Electrocardiogram. An organismal assay designed to capture information pertaining to the the organic processes and phenomena of an organism or any of its parts or of a particular bodily process. PERSON: Nicole Vasilevsky http://www.merriam-webster.com/dictionary/physiology physiological assay MRI. A technique used to create a representation or reproduction of an object's outward form; especially a visual representation (i.e., the formation of an image). PERSON: Nicole Vasilevsky http://en.wikipedia.org/wiki/Imaging imaging technique A physiological assay that utilizes systematic administration of defined procedures to measure specific psychological functions known to be linked to particular brain structures or pathways in humans. PERSON: Nicole Vasilevsky http://en.wikipedia.org/wiki/Neuropsychological_test neuropsychological testing An imaging technique, in which a gamma camera rotates around the patient and takes pictures from many angles, and a tomographic (cross-sectional) image is generated. PERSON: Nicole Vasilevsky SPECT http://www.medterms.com/script/main/art.asp?articlekey=18450 single photon emission computed tomography time to failure survival Consumption of liquids containing ethanol, including the behaviors associated with drinking the alcohol. cgrondin 2017-04-06T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=16.07d&code=C16273&ns=null&type=properties&key=null&b=1&n=0&vse=null influencing_factor alcohol drinking alcohol use ExO:0000104 alcohol consumption An arbitrary classification of a taxonomic group that is a division of a species. It usually arises as a consequence of geographical isolation within a species and is characterized by shared heredity, physical attributes and behavior, and in the case of humans, by common history, nationality, or geographic distribution. cgrondin 2017-04-06T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=16.07d&code=C17049&ns=null&type=properties&key=null&b=1&n=0&vse=null human_attribute racial group ExO:0000109 race A person having origins in any of the Black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American". cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=16.07d&code=C16352&ns=null&type=synonym&key=null&b=1&n=0&vse=null exposure_receptor Black Haitian Negro ExO:0000132 African American Denotes a person having origins in any indigenous people of Alaska and their descendants and who maintains tribal affiliation, or community or cultural attachment. The concept refers to population subgroups such as Eskimos, Aleuts, Inupiat, Yupik, Alutiiq, Egegik,and Pribilovian, Alaskan Athabascan, Tlingit, and Haida. The concept refers also to individuals who classify themselves as such. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=16.07d&code=C18237&ns=null&type=synonym&key=null&b=1&n=0&vse=null exposure_receptor Alaska Indian Alaskan Athabascan Aleut Alutiq Egegik Eskimo Haida Inupiat Pribilovian Tlingit Yupik ExO:0000133 Alaska Native Denotes a person having origins in one of the indigenous peoples of North America, who lived on the continent prior to the European colonization. The term includes individuals belonging to a large number of tribes, states, and ethnic groups, many of them still enduring as communities. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=16.07d&code=C43877&ns=null&type=synonym&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000134 American Indian A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C41260&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000135 Asian A person having origins in the original peoples of the Indian sub-continent. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C41262&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Asian Indians Indian ExO:0000136 Asian Indian A person of Central or South American culture or origin. cgrondin 2017-04-07T03:47:29Z exposure_receptor ExO:0000137 Central or South American A term sometimes used interchangeably with Mexican-American to denote an American citizen of Mexican decent. The term is a chosen identity of some Mexican-Americans in the United States. cgrondin 2017-04-07T03:47:29Z exposure_receptor Mexican-American ExO:0000138 Chicano A person having origins in any of the original peoples of China. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C43391&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000139 Chinese A person of Cuban culture or origin, regardless of race. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=16.07d&code=C107608&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Cuban-American Hispanic Latino ExO:0000140 Cuban Denotes a person from or of Cuba or an American citizen of Cuban descent. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C67115&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Cuban ExO:0000141 Cuban-American Denotes the inhabitants of the Dominican Republic, a person from there, or their descendants elsewhere. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C67117&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000142 Dominican A person having origins in any of the original peoples of the Philippine Islands. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C43393&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000143 Filipino Denotes inhabitants of Guam, an island in the North Pacific Ocean, about three-quarters of the way from Hawaii to the Philippines, south of the Northern Mariana Islands. cgrondin 2017-04-07T03:47:29Z exposure_receptor ExO:0000144 Guamanian A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=16.07d&code=C17459&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Central American Cuban Latino Mexican Puerto Rican South American Spanish origin ExO:0000145 Hispanic A general term for a group of culturally similar indigenous peoples inhabiting the Arctic regions of Canada, Greenland, Russia and the United States. In Alaska, the term Eskimo is commonly used, because it includes both Yupik and Inupiat, while Inuit is not accepted as a collective term. In Canada and Greenland, the term Eskimo has fallen out of favor, as it is considered pejorative by the natives and has been replaced by the term Inuit. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C86558&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Eskimo ExO:0000146 Inuit A person having origins in any of the original peoples of Japan. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C43392&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000147 Japanese A person having origins in any of the original peoples of Korea. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C43395&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000148 Korean A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C17459&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Hispanic Spanish origin Spanish origin ExO:0000149 Latino Denotes a person from or of Mexico. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=16.07d&code=C67113&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Hispanic ExO:0000150 Mexican Denotes an american citizen of Mexican descent. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C67114&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000151 Mexican-American A person having origins in any of the original peoples of Hawaii. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C43394&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Hawaiian ExO:0000152 Native Hawaiian A person of non-specified racial, cultural, or geographic origins. cgrondin 2017-04-07T03:47:29Z exposure_receptor Other ExO:0000153 Other Race A person having origins in the original peoples of the Pacific Islands, but not Guam, Hawaii, the Mariana Islands or Samoa. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C107602&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Other Pacific Islander ExO:0000154 Pacific Islander A person of Puerto Rican descent. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=16.07d&code=C67112&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000155 Puerto Rican A person having origins in any of the original peoples of Samoa. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C43407&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor ExO:0000156 Samoan A person having origins in any of the original peoples of Vietnam. cgrondin 2017-04-07T03:47:29Z exposure_receptor ExO:0000157 Vietnamese A person having origins in any of the original peoples of Europe, the Middle East, or North Africa. cgrondin 2017-04-07T03:47:29Z https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI_Thesaurus&version=17.03d&code=C41261&ns=null&type=properties&key=null&b=1&n=0&vse=null exposure_receptor Caucasian Caucasians Caucasoid Occidental Whites ExO:0000158 White Cardinal organ part which is bounded predominantly by bonafide boundaries. Examples: lobe of lung, osteon, acinus, submucosa, anterior leaflet of mitral valve, capsule of kidney, cortical bone, muscle fasciculus. fma FMA:14065 Organ component fma FMA:241981 Chemokine fma FMA:242193 Region of cerebral cortex Material anatomical entity which consists of the maximum number of discontinuous members of the same class. Examples: set of cranial nerves, ventral branches of aorta, set of mammary arteries, thoracic viscera, dental arcade. fma FMA:55652 Anatomical set Anatomical entity which has three or fewer spatial dimensions. Examples: hemoglobin molecule, mitochondrion, hepatocyte, erythrocyte, heart, head, blood, urine, peritoneal cavity, diaphragmatic surface of heart, inferior margin of liver, apex of lung. fma FMA:61775 Physical anatomical entity Cell appendage of the neuron which includes the axon and the dendrite. fma FMA:61814 Neurite Precuneate lobule Quadrate lobule fma FMA:61900 Precuneus Cuneate lobule Cuneus gyrus Cuneus of hemisphere fma FMA:61903 Cuneus Dorsal thalamus Dorsal thalamus (Anthoney) fma FMA:62007 Thalamus Ammon's horn Hippocampus major Hippocampus proper fma FMA:62493 Hippocampus B-lymphocyte fma FMA:62869 B lymphocyte T-lymphocyte fma FMA:62870 T lymphocyte Antibody fma FMA:62871 Immunoglobulin General anatomical term which refers to component of a fiber, e.g. collagen fibril or myofibril. fma FMA:62913 Fibril fma FMA:63493 C1 fma FMA:63834 Cytoskeleton Cell component which has as its parts a maximal phospholipids bilayer and two or more types of protein embedded in the bilayer. Examples: plasma membrane of hepatocyte, sarcolemma, plasma membrane of erythrocyte. Cell membrane Cellular membrane Cytoplasmic membrane Plasmalemma fma FMA:63841 Plasma membrane Anatomical structure which has as its parts one or more ordered aggregates of nucleotide, amino acid fatty acid or sugar molecules bonded to one another. Examples: collagen, DNA, neurotransmitter, troponin. fma FMA:63887 Biological macromolecule Cell component which has as its direct parts a portion of cytosol and one or more organelles. Examples: cytoplasm of hepatocyte, cytoplasm of erythrocyte, cytoplasm of thrombocyte, cytoplasm of neuron. Cytoplasma fma FMA:66835 Cytoplasm Membrana mitochondrialis Mitochondrial membrane Mitochondrion membrane fma FMA:66861 Membrane of mitochondrion Material anatomical entity which is generated by coordinated expression of the organism's own genes that guide its morphogenesis; has inherent 3D shape; its parts are connected and spatially related to one another in patterns determined by coordinated gene expression. Examples: heart, right ventricle, mitral valve, myocardium, endothelium, lymphocyte, fibroblast, thorax, cardiovascular system, hemoglobin, T cell receptor. Biological structure fma FMA:67135 Anatomical structure Physical anatomical entity which has mass. Examples: hemoglobin molecule, mitochondrion, hepatocyte, erythrocyte, heart, head, blood, urine. fma FMA:67165 Material anatomical entity Cell component which consists of the plasma membrane and the cytoplasm surrounding the nucleus. Cell soma fma FMA:67301 Cell body Cell component which consists of parts of the cytoplasm and plasma membrane protruding from the cell body. Examples: cilium, microvillus, axon. fma FMA:67304 Cell appendage Cell appendage of a neuron that consists of an axon hillock, an axon proper, axon collaterals and an axon terminal. fma FMA:67308 Axon Cell appendage of a neuron that consists of the dendrite proper and the dendritic spines. fma FMA:67314 Dendrite Cardinal organ part which is a fiat subdivision of an organ. Examples: lingula of left lung, tail of pancreas, artery, trochanter, nodulus of semilunar valve, right side of heart, duodenum, fundus of stomach. fma FMA:67619 Organ region fma FMA:67906 Protein complex Anatomical structure which has as its boundary the external surface of a maximally connected plasma membrane. Examples: lymphocyte, fibroblast, erythrocyte, neuron. Normal cell fma FMA:68646 Cell Visceral efferent neuron fma FMA:80122 Preganglionic neuron anatomical structure which has as its direct parts two or more types of tissue and is continuous with one or more anatomical structures likewise constituted by two or more portions of tissues distinct from those of their complement. Examples: osteon, cortical bone, neck of femur, bronchopulmonary segment, left lobe of liver, anterior right side of heart, interventricular branch of left coronary artery, right atrium, mitral valve, head of pancreas. fma FMA:82472 Cardinal organ part General anatomical term which refers to a chamber of an organ with cavitated organ parts. Examples: right ventricle of heart, lateral ventricle of brain. fma FMA:82553 Ventricle Organ component which is part of the brain or spinal cord. fma FMA:83153 Organ component of neuraxis Neuraxis gyrus fma FMA:83874 Gyrus of neuraxis Basal ganglia Basal ganglia set fma FMA:84013 Set of basal ganglia fma FMA:84050 Cytokine fma FMA:85549 Membrane layer of organelle Cardinal organ part which is a fiat subdivision of an organ component. Examples: cervical part of wall of esophagus, mucosa of body of stomach. Organ component region fma FMA:86103 Region of organ component Organ region with one or more anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyeball. Organ region with fixed fiat boundary Segment of organ fma FMA:86140 Organ segment fma FMA:86578 Interleukin IL-12 fma FMA:86579 Interleukin-12 Familiar examples of invertebrates include arthropods (insects, arachnids, crustaceans, and myriapods), mollusks (chitons, snails, bivalves, squids, and octopuses), annelids (earthworms and leeches), and cnidarians (hydras, jellyfishes, sea anemones, and corals).[wikipedia] Invertebrates are animals that neither possess nor develop a vertebral column (commonly known as a backbone or spine), derived from the notochord. This includes all animals apart from the subphylum Vertebrata. Damion Dooley https://en.wikipedia.org/wiki/Invertebrate animal invertebrate animal A cell phenotype in which DNA is broken into small fragments. midori 2011-04-19T02:59:38Z DNA fragmentation fission_yeast_phenotype fragmented nucleus FYPO:0000160 Use 'fragmented DNA' (FYPO:0000160) or one of its descendants if DNA was detected using a method that can resolve molecule sizes (e.g. gel electrophoresis) or detect DNA ends (e.g. TUNEL assay). Otherwise, consider using 'fragmented nucleus' (FYPO:0001919) or one of its descendants. fragmented DNA socio-demographic and economic characteristics gender An organismal quality inhering in a bearer by virtue of the bearer's preference towards a range of characteristics pertaining to, and differentiating between, masculinity and femininity. Wikipedia:Gender|PATO:0000047 gender cognitive and psychological measurements cognitive functioning A psychological measurement of some aspect of intellectual functions such as memory, problem solving, and comprehension. Wikipedia:Cognition cognitive measurement cognitive functioning ADAS A cognitive measurement that is an output (score) from the Alzheimer's Disease Assessment Scale. Alzheimer's Disease Assessment Scale score cognitive functioning MMSE A cognitive measurement that is an output (score) from the Mini-Mental State Exam. Mini-Mental State Exam score cognitive functioning MoCA A cognitive measurement that is the output (score) from the Montreal Cognitive Assessment Test (MoCA) for Dementia Montreal Cognitive Assessment Test score cognitive functioning CDR A cognitive measurement that is the output (score) from the Clinical Dementia Rating Scale. Clinical Dementia Rating Scale score Damion Dooley diagnostic test A gene that originates from the genome of a danio rerio. danio rerio gene A sequence alteration that is very rare allele in a population (typically <1%), or an experimentally-induced variation that derives from a wild-type feature in a given strain. mutation The lipid bilayer surrounding any of the compartments of the Golgi apparatus. cellular_component GO:0000139 Golgi membrane An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. GO:0007255 Wikipedia:MAPK_cascade Wikipedia:Mitogen-activated_protein_kinase MAP kinase cascade MAP kinase kinase kinase cascade MAPK signal transduction MAPKKK cascade mitogen-activated protein kinase cascade ERK/MAPK cascade MAPKKK cascade during sporulation biological_process MAPK signaling MAPK signalling GO:0000165 MAPK cascades lie downstream of many cell surface receptors and cooperate in transmitting various extracellular signals to the nucleus. One way by which the specificity of each cascade is regulated is through the existence of several distinct components in each tier of the different cascades. The cascades are typically named according to the component in the MAPK tier. MAPK cascade The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions. Wikipedia:Autophagy_(cellular)#Selective_autophagy Wikipedia:Mitophagy mitochondrion autophagy biological_process mitophagy GO:0000422 autophagy of mitochondrion The selective autophagy process in which a mitochondrion is degraded by macroautophagy. macromitophagy biological_process GO:0000423 Note that this terms refers to the macroautophagy process and is named by common usage. Be aware that there are a separate micromitophagy and mitophagy by induced vacuole formation processes. mitophagy A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. proteasome 26S proteasome cellular_component GO:0000502 proteasome complex A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities. biological_process GO:0001508 Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so. action potential The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. biological_process GO:0001774 microglial cell activation Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. Wikipedia:Immune_system biological_process GO:0002376 Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501). immune system process A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome). GO:0008372 NIF_Subcellular:sao1337158144 cell or subcellular entity cellular component cellular_component subcellular entity GO:0005575 Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. cellular_component A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds. fibrinogen fibrinogen alpha chain fibrinogen beta chain fibrinogen gamma chain cellular_component GO:0005577 fibrinogen complex A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. Wikipedia:Complement_membrane_attack_complex MAC TCC terminal complement complex membrane attack complex protein alphaM chain membrane attack complex protein beta2 chain cellular_component GO:0005579 membrane attack complex A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. https://github.com/geneontology/go-ontology/issues/17776 Wikipedia:Intracellular internal to cell intracellular protoplasm cellular_component nucleocytoplasm protoplast GO:0005622 intracellular anatomical structure A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. NIF_Subcellular:sao1702920020 Wikipedia:Cell_nucleus cell nucleus horsetail nucleus cellular_component GO:0005634 nucleus A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. NIF_Subcellular:sao1860313010 Wikipedia:Mitochondrion mitochondria cellular_component GO:0005739 Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.) mitochondrion A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. NIF_Subcellular:sao585356902 Wikipedia:Lysosome cellular_component GO:0005764 lysosome A vacuole to which materials ingested by endocytosis are delivered. NIF_Subcellular:sao1720343330 Wikipedia:Endosome cellular_component GO:0005768 endosome A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. NIF_Subcellular:nlx_subcell_20090701 cellular_component GO:0005769 early endosome A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. PVC NIF_Subcellular:nlx_subcell_20090702 prevacuolar compartment cellular_component GO:0005770 late endosome A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. Wikipedia:Vacuole cellular_component vacuolar carboxypeptidase Y GO:0005773 vacuole A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy. NIF_Subcellular:sao8663416959 autophagic vacuole cellular_component initial autophagic vacuole GO:0005776 autophagosome The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). NIF_Subcellular:sao1036339110 Wikipedia:Endoplasmic_reticulum ER cellular_component GO:0005783 endoplasmic reticulum A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. Golgi NIF_Subcellular:sao451912436 Wikipedia:Golgi_apparatus Golgi complex Golgi ribbon cellular_component GO:0005794 Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon. Golgi apparatus The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. trans face NIF_Subcellular:sao9456487 TGN trans Golgi network cellular_component Golgi trans face Golgi trans-face late Golgi maturing face GO:0005802 There are different opinions about whether the TGN should be considered part of the Golgi apparatus or not. We follow Alberts et al, 1994 (ISBN:0815316194), who consider it to be a part. trans-Golgi network Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. NIF_Subcellular:sao1846835077 Wikipedia:Microtubule microtubuli microtubulus neurotubule cellular_component GO:0005874 microtubule A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. MetaCyc:P105-PWY MetaCyc:P42-PWY MetaCyc:TCA Wikipedia:Tricarboxylic_acid_cycle Krebs cycle TCA cycle citric acid cycle biological_process GO:0006099 tricarboxylic acid cycle The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. GO:0055133 Wikipedia:DNA_replication biological_process GO:0006260 DNA biosynthesis is only part of this process. See also the biological process terms 'DNA-dependent DNA replication ; GO:0006261' and 'RNA-dependent DNA replication ; GO:0006278'. DNA replication The cellular synthesis of RNA on a template of DNA. GO:0006350 GO:0061018 GO:0061022 cellular transcription transcription Wikipedia:Transcription_(genetics) DNA-dependent transcription cellular transcription, DNA-dependent transcription, DNA-dependent biological_process transcription regulator activity GO:0006351 transcription, DNA-templated The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. GO:0006416 GO:0006453 GO:0043037 Wikipedia:Translation_(genetics) protein anabolism protein biosynthesis protein biosynthetic process protein formation protein synthesis protein translation biological_process GO:0006412 translation The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. jl 2012-12-13T16:25:32Z GO:0015457 GO:0015460 GO:0044765 small molecule transport solute:solute exchange biological_process single-organism transport GO:0006810 Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0006811 ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006834 GO:0016974 sodium/potassium transport sodium transport mitochondrial sodium/calcium ion exchange sodium:calcium exchange sodium:solute transport biological_process sodium channel auxiliary protein activity GO:0006814 sodium ion transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. biological_process GO:0006869 lipid transport A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. GO:0016194 GO:0016195 Wikipedia:Exocytosis vesicle exocytosis biological_process nonselective vesicle exocytosis GO:0006887 exocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. GO:0016193 GO:0016196 GO:0098701 Wikipedia:Endocytosis endocytic import into cell vesicle endocytosis plasma membrane invagination biological_process nonselective vesicle endocytosis GO:0006897 endocytosis A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. Wikipedia:Phagocytosis biological_process GO:0006909 phagocytosis The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. GO:0016238 Wikipedia:Autophagy_(cellular) biological_process GO:0006914 autophagy The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). Wikipedia:Chemotaxis taxis in response to chemical stimulus biological_process GO:0006935 chemotaxis Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. biological_process GO:0006955 immune response A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. plasma membrane organisation biological_process plasma membrane organization and biogenesis GO:0007009 plasma membrane organization Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Wikipedia:Cell_signaling biological_process GO:0007154 cell communication The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. dos 2014-04-15T15:59:10Z GO:0098602 Wikipedia:Cell_adhesion biological_process cell adhesion molecule activity single organism cell adhesion GO:0007155 cell adhesion The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. GO:0023014 GO:0023015 GO:0023016 GO:0023033 GO:0023045 MIPS_funcat:30 Wikipedia:Signal_transduction signal transduction by cis-phosphorylation signal transduction by conformational transition signal transduction by protein phosphorylation signal transduction by trans-phosphorylation signaling cascade signalling cascade biological_process signaling pathway signalling pathway GO:0007165 Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not. signal transduction A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0030179 Wikipedia:Notch_signaling_pathway N signaling pathway N signalling pathway Notch receptor signaling pathway Notch receptor signalling pathway Notch signalling pathway Notch-receptor signaling pathway Notch-receptor signalling pathway biological_process GO:0007219 Notch signaling pathway The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. signal transmission across a synapse synaptic transmission Wikipedia:Neurotransmission biological_process neurotransmission GO:0007268 chemical synaptic transmission The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. janelomax 2012-09-20T14:06:08Z GO:0044708 Wikipedia:Behavior behavioral response to stimulus behaviour behavioural response to stimulus biological_process single-organism behavior GO:0007610 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews. 2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis). behavior A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. NIF_Subcellular:sao1071221672 Wikipedia:Synaptic_vesicle docked vesicle cellular_component GO:0008021 This term should not be confused with GO:0097547 'synaptic vesicle protein transport vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles. synaptic vesicle A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. janelomax jl 2012-09-19T15:05:24Z GO:0000004 GO:0007582 GO:0044699 Wikipedia:Biological_process biological process physiological process biological_process single organism process single-organism process GO:0008150 Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this. Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. biological_process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. jl 2012-10-17T15:46:40Z GO:0044236 GO:0044710 Wikipedia:Metabolism metabolism metabolic process resulting in cell growth metabolism resulting in cell growth multicellular organism metabolic process biological_process single-organism metabolic process GO:0008152 Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions. metabolic process Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). biological_process accidental cell death necrosis GO:0008219 This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term. cell death The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. jl 2012-10-17T15:52:35Z GO:0044243 GO:0044712 Wikipedia:Catabolism breakdown catabolism degradation multicellular organismal catabolic process biological_process single-organism catabolic process GO:0009056 catabolic process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. janelomax jl 2012-12-11T16:56:55Z GO:0008151 GO:0044763 GO:0050875 cell physiology cellular physiological process cell growth and/or maintenance biological_process single-organism cellular process GO:0009987 cellular process The lipid bilayer surrounding an endosome. NIF_Subcellular:sao978443756 endosomal membrane cellular_component GO:0010008 endosome membrane Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). https://github.com/geneontology/go-ontology/issues/22557 Wikipedia:Regulation_of_gene_expression regulation of protein expression biological_process gene regulation regulation of gene product expression GO:0010468 This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation. regulation of gene expression The lipid bilayer surrounding any membrane-bounded vesicle in the cell. NIF_Subcellular:sao1153182838 cellular_component GO:0012506 vesicle membrane An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. pr 2013-07-02T09:44:28Z GO:0097481 GO:0097483 NIF_Subcellular:sao1196688972 Wikipedia:Postsynaptic_density neuronal postsynaptic density post synaptic density post-synaptic density postsynaptic density of dendrite cellular_component GO:0014069 postsynaptic density The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester. biological_process GO:0015914 phospholipid transport A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. 2014-03-06T11:37:54Z GO:0098589 GO:0098805 Wikipedia:Biological_membrane membrane region region of membrane whole membrane cellular_component GO:0016020 membrane A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. GO:0006899 vesicle transport vesicular transport nonselective vesicle transport biological_process protein sorting along secretory pathway vesicle trafficking GO:0016192 vesicle-mediated transport A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers. NIF_Subcellular:sao120573470 Wikipedia:Inclusion_bodies neuronal cytoplasmic inclusion cellular_component cellular inclusion GO:0016234 inclusion body The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. Wikipedia:Phosphorylation biological_process GO:0016310 phosphorylation The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. Wikipedia:Dephosphorylation biological_process GO:0016311 dephosphorylation The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. GO:0006485 GO:0016927 Wikipedia:SUMO_protein SUMO-protein conjugation protein sumolation small ubiquitin-related protein 1 conjugation sumoylation biological_process GO:0016925 protein sumoylation The covalent attachment of a myristoyl group to a protein. GO:0018319 protein amino acid myristoylation biological_process GO:0018377 protein myristoylation Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. Wikipedia:Calcium_signaling calcium ion signaling calcium signaling calcium signalling calcium-mediated signalling biological_process GO:0019722 calcium-mediated signaling The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. biological_process GO:0022402 cell cycle process One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. biological_process GO:0022403 Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). cell cycle phase The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions. biological_process GO:0022610 biological adhesion The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. jl 2010-02-16T09:30:50Z GO:0023046 GO:0044700 biological signaling signaling process signalling biological_process signalling process single organism signaling GO:0023052 Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. signaling A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. Wikipedia:Cell_junction cellular_component GO:0030054 cell junction A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. cellular_component GO:0030312 The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'. external encapsulating structure The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic. Wikipedia:Growth_cone cellular_component GO:0030426 growth cone Any part of a cell where non-isotropic growth takes place. GO:0000134 GO:0030483 cellular_component GO:0030427 site of polarized growth The lipid bilayer surrounding a cytoplasmic vesicle. cellular_component GO:0030659 cytoplasmic vesicle membrane A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. GO:0005578 NIF_Subcellular:nlx_subcell_20090513 Wikipedia:Extracellular_matrix proteinaceous extracellular matrix matrisome cellular_component GO:0031012 extracellular matrix A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. NIF_Subcellular:sao830981606 cellular_component intracellular membrane GO:0031090 organelle membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. NIF_Subcellular:sao1687101204 cellular_component GO:0031965 nuclear membrane Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. NIF_Subcellular:sao1045389829 cellular_component GO:0031966 mitochondrial membrane A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle. suborganelle compartment cellular_component GO:0031984 Note that this term refers to membrane-bounded compartments that are not considered organelles in their own right, but form parts of larger organelles. organelle subcompartment The process in which a methyl group is covalently attached to a molecule. Wikipedia:Methylation biological_process GO:0032259 methylation The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites. neuron cell body membrane neuronal cell soma membrane cellular_component GO:0032809 neuronal cell body membrane A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. GO:0043234 macromolecular complex macromolecule complex protein containing complex protein complex protein-protein complex cellular_component GO:0032991 A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole. protein-containing complex A macromolecular complex containing both protein and DNA molecules. DNA-protein complex cellular_component GO:0032993 Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here. protein-DNA complex An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed. NIF_Subcellular:birnlex_1152_2 Wikipedia:Nodes_of_Ranvier cellular_component node of Ranvier axon GO:0033268 node of Ranvier Binding to an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels. molecular_function GO:0035255 ionotropic glutamate receptor binding The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). bf 2012-04-26T01:47:12Z protein modification biological_process GO:0036211 protein modification process The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane. bf 2014-06-26T11:03:08Z kiss-and-run synaptic vesicle recycling kiss-and-stay synaptic vesicle recycling biological_process GO:0036465 synaptic vesicle recycling A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons. bf 2013-03-27T17:22:44Z neurotrophin receptor signaling pathway biological_process GO:0038179 There are two classes of receptors for neurotrophins: p75 and the Trk family of tyrosine kinase receptors. neurotrophin signaling pathway The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. biological_process GO:0042118 endothelial cell activation The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. Wikipedia:Myelin biological_process myelinogenesis GO:0042552 myelination A prolongation or process extending from a cell, e.g. a flagellum or axon. cell process cellular process cellular projection cellular_component GO:0042995 cell projection A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. NIF_Subcellular:sao867568886 neuron process neuron protrusion neuronal cell projection neurite cellular_component nerve fiber GO:0043005 neuron projection A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity. NIF_Subcellular:sao1799103720 Wikipedia:Dendritic_spine dendrite spine branched dendritic spine mushroom dendritic spine sessile dendritic spine stubby dendritic spine thin dendritic spine cellular_component GO:0043197 dendritic spine An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. FMA:62983 NIF_Subcellular:sao593830697 Wikipedia:Myelin Schwann cell myelin sheath astrocyte sheath oligodendrocyte myelin sheath cellular_component GO:0043209 myelin sheath Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. NIF_Subcellular:sao1539965131 Wikipedia:Organelle cellular_component GO:0043226 organelle The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. Wikipedia:Posttranslational_modification PTM post-translational amino acid modification post-translational modification posttranslational amino acid modification posttranslational modification posttranslational protein modification biological_process GO:0043687 This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term. post-translational protein modification The chemical reactions and pathways by which individual cells transform chemical substances. cellular metabolism biological_process intermediary metabolism GO:0044237 cellular metabolic process The migrating motile tip of a growing nerve cell axon. jl 2010-02-04T03:57:16Z NIF_Subcellular:sao1594955670 NIF_Subcellular:sao203987954 axon growth cone cellular_component GO:0044295 axonal growth cone A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck. jl 2010-02-05T04:25:10Z spine NIF_Subcellular:sao1145756102 cellular_component GO:0044309 neuron spine Any process evolved to enable an interaction with an organism of a different species. https://github.com/geneontology/go-ontology/issues/20191 interaction with another species interspecies interaction interspecies interaction between organisms interspecies interaction with other organisms biological_process GO:0044419 biological process involved in interspecies interaction between organisms A distinct period or stage in a biological process or cycle. jl 2014-07-16T13:12:40Z biological_process GO:0044848 Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase. biological phase Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. Wikipedia:Lipid_raft lipid raft cellular_component GEM domain glycolipid-enriched membrane domain GO:0045121 membrane raft The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. NIF_Subcellular:sao914572699 Wikipedia:Chemical_synapse synaptic junction mixed synapse cellular_component electrotonic synapse GO:0045202 synapse A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids. https://github.com/geneontology/go-ontology/issues/20452 pore cellular_component channel-forming toxin activity pore-forming toxin activity GO:0046930 pore complex A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. biological_process GO:0048143 astrocyte activation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. GO:0051869 physiological response to stimulus biological_process GO:0050896 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus The directed movement of substances into, out of, or within the nucleus. Wikipedia:Nuclear_transport nucleus transport biological_process GO:0051169 nuclear transport Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. jl 2013-12-18T13:51:04Z GO:1902578 establishment and maintenance of localization establishment and maintenance of position localisation establishment and maintenance of cellular component location establishment and maintenance of substance location establishment and maintenance of substrate location biological_process single organism localization single-organism localization GO:0051179 localization Reactions triggered in response to the presence of a virus that act to protect the cell or organism. antiviral response defence response to virus defense response to viruses biological_process GO:0051607 defense response to virus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. GO:0009613 GO:0042828 biological_process GO:0051707 response to other organism The addition of a sulfate group to a molecule. phase II metabolism sulfonation sulfur addition sulphation sulphur addition biological_process GO:0051923 sulfation The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. tb 2015-10-21T13:22:47Z GO:0090662 membrane transport ATP hydrolysis coupled transmembrane transport biological_process GO:0055085 Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes. transmembrane transport A cytosolic protein complex that is capable of activating caspase-1. dph 2015-05-08T14:30:54Z cellular_component GO:0061702 inflammasome complex Any process that modulates a measurable attribute of any biological process, quality or function. regulation biological_process GO:0065007 biological regulation The covalent attachment and further modification of carbohydrate residues to a substrate molecule. Wikipedia:Glycosylation biological_process GO:0070085 glycosylation A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. exocytic constitutive secretory pathway transport vesicle exocytotic vesicle cellular_component GO:0070382 exocytic vesicle A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity. mah 2009-07-02T02:41:44Z externalization of phosphatidylserine biological_process GO:0070782 In normal cells, phosphatidylserine residues are found exclusively on the inner side of the cellular membrane. During apoptosis, phosphatidylserine is transported to the outer cell surface by scramblase proteins. This event acts as an "eat-me" signal for macrophages to dispose of the dying cell. When annotating to this term, curators should be aware of the following: 1) phosphatidylserine exposure on the cell surface can occur in circumstances other than apoptosis (for example, when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system, see PMID:21107324). Do not annotate to GO:0070782 unless phosphatidylserine exposure is shown to be part of an apoptotic event. 2) Caution should be applied when a study quotes annexin V assays. The annexin A5 protein binds to phosphatidylserine-containing membrane surfaces, which are usually only present on the inner leaflet of the membrane. However, in cells undergoing apoptosis, phosphatidylserine becomes exposed on the outer leaflet of the membrane. A positive annexin assay can therefore be linked to apoptotic death, but it shouldn't be confused with molecular events strictly involved in the process of phosphatidylserine exposure. phosphatidylserine exposure on apoptotic cell surface The process of removing one or more methyl groups from a molecule. mah 2009-10-29T03:12:51Z biological_process GO:0070988 demethylation The process of cell death in a neuron. mah 2009-11-03T02:37:17Z neuron cell death neuronal cell death biological_process GO:0070997 This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate. neuron death A process in which a potassium ion is transported from one side of a membrane to the other. mah 2010-09-03T02:43:49Z GO:0010163 potassium ion membrane transport high affinity potassium ion import high affinity potassium ion uptake high-affinity potassium ion import high-affinity potassium ion uptake biological_process GO:0071805 Note that this term is not intended for use in annotating lateral movement within membranes. potassium ion transmembrane transport The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors. pr 2012-02-16T05:32:29Z beta-amyloid clearance biological_process GO:0097242 amyloid-beta clearance The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added. pr 2012-07-03T01:12:19Z biological_process GO:0097354 prenylation Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein. pr 2012-11-06T16:26:08Z NIF_Subcellular:sao4933778419 cellular_component cytoplasmic inclusion GO:0097413 Lewy body The lipid bilayer that forms the outer-most layer of an organelle. dos 2014-02-26T13:41:31Z cellular_component GO:0098588 Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes. bounding membrane of organelle The part of a synapse that is part of the post-synaptic cell. cellular_component GO:0098794 postsynapse Any protein complex that is part of a membrane. cellular_component GO:0098796 membrane protein complex Any protein complex that is part of the plasma membrane. cellular_component GO:0098797 plasma membrane protein complex A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it. cellular_component GO:0098857 membrane microdomain The directed movement of organelles or molecules along microtubules in axons. Wikipedia:Axoplasmic_transport axon cargo transport axoplasmic transport biological_process GO:0098930 axonal transport A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. cellular_component GO:0099080 supramolecular complex A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. cellular_component GO:0099572 postsynaptic specialization A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. kmv 2019-08-12T18:01:37Z cellular_component GO:0110165 cellular anatomical entity A protein complex which is capable of catalytic activity. bhm 2013-11-13T16:18:47Z enzyme complex cellular_component GO:1902494 catalytic complex The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle. sjp 2014-05-08T09:19:51Z neurofibrillary tangle formation flame-shaped neurofibrillary tangle assembly flame-shaped neurofibrillary tangle formation star-shaped neurofibrillary tangle assembly star-shaped neurofibrillary tangle formation biological_process GO:1902988 Neurofibrillary tangles have been found in aging population; their formation is increased in Alzheimer's disease patients (and in other neurological diseases) compared to normal controls (see PMID:848276 and PMID:8584267). neurofibrillary tangle assembly The process in which glucose is transported across a membrane. vw 2015-09-04T17:20:16Z GO:0015758 biological_process glucose transport GO:1904659 glucose transmembrane transport A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph. pr 2015-06-18T08:42:53Z cellular_component GO:1990777 lipoprotein particle A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6. bf 2015-09-14T15:59:54Z Wnt receptor complex Wnt-FZD-LRP5/6 trimeric complex Wnt.Fz.LRP ternary complex Fz/Wnt/LRP6 complex WNT-FZD-LRP5 complex WNT-FZD-LRP6 complex cellular_component Frizzled-LRP5/6 complex Wnt-induced Frizzled-LRP5/6 complex GO:1990851 Given the number of Wnt proteins, Frizzled proteins and LRP proteins, many different trimeric complexes are likely to form. Wnt-Frizzled-LRP5/6 complex A broad term referring to clinical psychotherapy that uses techniques derived from behaviorism. Therapeutic approach that may employ classical conditioning, operant learning techniques, or other behavioral techniques, in an attempt to eliminate or modify problem behavior, addressing itself primarily to the client's overt behavior, as opposed to thoughts, feelings, or other cognitive processes. http://homosaurus.org/v2/behaviouralTherapy behavioral intervention https://en.wikipedia.org/wiki/Behaviour_therapy https://en.wikipedia.org/wiki/Category:Behavior_therapy https://www.wikidata.org/wiki/Q1483649 behavior therapy behavioral psychotherapy behavioral therapy behavioral therapies http://id.loc.gov/authorities/subjects/sh85012900 RC489.B4 94.33 http://purl.bioontology.org/ontology/MEDDRA/10074786 http://purl.bioontology.org/ontology/MESH/D001521 http://purl.bioontology.org/ontology/SNOMEDCT/166001 A case report is a detailed report of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient. https://en.wikipedia.org/wiki/Case_report case report case reports A person who serves as a subject for artwork or fashion, usually in the medium of photography but also for painting or drawing. https://en.wikipedia.org/wiki/Category:Models_(profession) fashion model model models Mortality from all causes in a given time interval, for a given population. crude death rate A phenotypic abnormality. UMLS:C4021819 Organ abnormality human_phenotype HP:0000118 This is the root of the phenotypic abnormality subontology of the HPO. Phenotypic abnormality An abnormality of the nervous system. HP:0001333 HP:0006987 Brain and/or spinal cord issue MSH:D009421 SNOMEDCT_US:88425004 UMLS:C0497552 Abnormality of the nervous system Neurologic abnormalities Neurological abnormality HP:0000707 The nervous system comprises the neuraxis (brain, spinal cord, and ventricles), the autonomic nervous system, the enteric nervous system, and the peripheral nervous system. Abnormality of the nervous system MSH:D057565 SNOMEDCT_US:20602000 UMLS:C0085632 Lack of feeling, emotion, interest human_phenotype HP:0000741 Apathy An abnormal shift in patterns of thinking, acting, or feeling. SNOMEDCT_US:102943000 SNOMEDCT_US:192073007 UMLS:C0240735 Personality change Personality changes human_phenotype HP:0000751 This term refers to changes in personality that are perceived as being abnormal. It does not refer to the usual gradual personality changes that tend to accompany aging and certain life situations. Personality changes Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic contractions. MEDDRA:10047700 MSH:D014839 SNOMEDCT_US:249497008 SNOMEDCT_US:300359004 SNOMEDCT_US:422400008 UMLS:C0042963 Emesis Throwing up Vomiting human_phenotype HP:0002013 Vomiting Progressive loss of neural cells and tissue. MSH:D009410 MSH:D019636 UMLS:C0027746 UMLS:C0524851 UMLS:C4020854 Ongoing loss of nerve cells Neuro-degenerative disease Neurodegenerative disease Progressive neurodegenerative disorder HP:0002180 Neurodegeneration Pathological protein aggregates formed by hyperphosphorylation of a microtubule-associated protein known as tau, causing it to aggregate in an insoluble form. HP:0003132 HP:0007070 MSH:D016874 SNOMEDCT_US:85775002 UMLS:C0085400 Neurofibrillary tangles composed of disordered microtubules in neurons Paired helical filaments human_phenotype HP:0002185 Neurofibrillary tangles A defect in the understanding of complex motor commands and in the execution of certain learned movements, i.e., deficits in the cognitive components of learned movements. MSH:D001072 SNOMEDCT_US:68345001 SNOMEDCT_US:6950007 UMLS:C0003635 human_phenotype Apraxias HP:0002186 Apraxia An acquired language impairment of some or all of the abilities to produce or comprehend speech and to read or write. MSH:D001037 SNOMEDCT_US:87486003 UMLS:C0003537 Difficulty finding words Losing words Loss of words HP:0002381 Aphasia is caused by brain injury. The most common cause is stroke, but aphasia can also be caused by other factors such as head trauma, brain tumors, or infections. Aphasia MSH:D000690 SNOMEDCT_US:86044005 UMLS:C0002736 human_phenotype Lou Gehrig's disease HP:0007354 Amyotrophic lateral sclerosis A functional abnormality of the immune system. peter 2011-02-07T04:28:55Z UMLS:C4023616 HP:0010978 Abnormality of immune system physiology An allergy is an immune response or reaction to substances that are usually not harmful. peter 2013-11-07T07:47:22Z MSH:D006967 SNOMEDCT_US:419076005 UMLS:C1527304 Allergy HP:0012393 Allergy A functional anomaly of the nervous system. peter 2014-01-19T08:02:46Z UMLS:C4022811 Abnormality of nervous system physiology human_phenotype HP:0012638 Abnormal nervous system physiology A structural anomaly of the nervous system. peter 2014-01-19T08:03:08Z Fyler:4135 Fyler:4300 UMLS:C4022810 Abnormal nervous system morphology Abnormal shape of nervous system Abnormality of nervous system morphology human_phenotype HP:0012639 Abnormal nervous system morphology A distortion of the sense of taste, often characterized by the sensation of a metallic taste. 2017-08-12T13:35:52Z peter Altered sense of taste Dysgeusia Metallic taste Metallic taste in mouth Parageusia Information about close relatives of an individual who is the proband of a study or who is being investigated with the goal of identifying a medical diagnosis. Usually, the family history includes information from three generations of relatives, including children, brothers and sisters, parents, aunts and uncles, nieces and nephews, grandparents, and cousins. 2019-02-14T11:40:50Z peter This subontology is intended to help record summary information about family members if only a limited amount of information is available or required. Family history In a medical encounter, the physician generally will interview the patient about his or her current problem, and may perform additional testing. The past medical history (PMH) in contrast records information about the patient's medical, personal and family history that might be relevant to the presenting illness or to provide optimal clinical management. The PMH generally includes (if relevant) other major illnesses, hospitalizations, surgeries, injuries, allergies, gynecologic and obstetric history, family history, personal history including occupational history, alcohol and drug use, etc. 2019-03-03T16:39:26Z peter This subontology of the HPO is not intended to provide all needed terms to describe the past medical history, but rather to be combined with other ontologies such as MONDO in order to capture information that is often needed to properly assess phenotypic findings related to a presenting medical problem. Past medical history Activation of the brain's innate immune system in response to an inflammatory challenge and is characterized by a host of cellular and molecular changes within the brain. 2021-01-09T17:51:49Z peter Neuroinflammation data item Data items include counts of things, analyte concentrations, and statistical summaries. a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements. 2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers. 2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum. 2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym. 2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/ JAR: datum -- well, this will be very tricky to define, but maybe some information-like stuff that might be put into a computer and that is meant, by someone, to denote and/or to be interpreted by some process... I would include lists, tables, sentences... I think I might defer to Barry, or to Brian Cantwell Smith JAR: A data item is an approximately justified approximately true approximate belief PERSON: Alan Ruttenberg PERSON: Chris Stoeckert PERSON: Jonathan Rees data data item information content entity Examples of information content entites include journal articles, data, graphical layouts, and graphs. A generically dependent continuant that is about some thing. An information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity 2014-03-10: The use of "thing" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ). information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907). Previous. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity. PERSON: Chris Stoeckert OBI_0000142 information content entity measurement datum Examples of measurement data are the recoding of the weight of a mouse as {40,mass,"grams"}, the recording of an observation of the behavior of the mouse {,process,"agitated"}, the recording of the expression level of a gene as measured through the process of microarray experiment {3.4,luminosity,}. A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device. 2/2/2009 is_specified_output of some assay? person:Chris Stoeckert OBI_0000305 group:OBI measurement datum A woman who is pregnant. Could reuse: http://purl.obolibrary.org/obo/ontoneo/ONTONEO_00000197 pregnant woman It is the process by which cells undergo apoptosis in a controlled manner through the interaction of a death factor and its receptor. It plays a significant role in immune system homeostasis. guest 2009-12-08T09:48:03Z AICD idomal_namespace IDOMAL:0000816 activation-induced cell death IDOMAL:0000816 Any primate that is not a prosimian (lemurs and tarsiers) or an ape. louis 2009-06-03T02:20:26Z idomal_namespace IDOMAL:0001219 monkey IDOMAL:0001219 a positive regulation that one interactor up-regulates another. YH up-regulate, up-regulations, up-regulated, up-regulating, upregulate, upregulations, upregulated, upregulating up-regulation a biological interaction that involves two cells as interactors. YL.YH. ZX. cell-cell interaction a gene expression regulation process that involves the regulation of a gene transcription. YH, AO, JH regulation of gene transcription transcribed, transcribed by, regulates the transcription of, regulated the transcription of, regulates // transcription, regulated // transcription, under the control of // transcription, essential for // transcription, trascription depends, transcription // dependent, control // transcription, controlling // transcription, requires // transcription amod(transcription, controlling), amod(transcription, dependent), amod(expression, dependent), nsubj(dependent, transcription), nsubj(control, expression), nmod:for(regulator, transcription), nmod:of(activator, transcription), nsubjpass(recognized, promoter) regulation of transcription a negative regulation that one interactor down-regulates another. YH, ZX down-regulate, down-regulated, down-regulates, down-regulating, down-regulation, downregulate, downregulated, downregulates, downregulating, downregulation, downmodulation, depress, depressed, depresses, depressing, suppress, suppressed, suppresses, suppressing, suppression, suppressor, repress, repressed, represses, repressing, repression, repressor, repressors down-regulation an enzymatic reaction where a molecule gains oxygen. YH, ZX oxidate, oxidated, oxidates, oxidating, oxidation, oxidise, oxidised, oxidises, oxidising, oxidize, oxidized, oxidizes, oxidizing oxidation A regulation represents a regulatory interaction between two interactors. YH, ZX, AO, JH regulate, regulated, regulates, regulating, regulation, regulator, modulate, modulated, modulates, modulating, modulation, mediate, mediated, mediates, mediating, influence, influenced, influences, influencing, affect, affected, affecting, affects, impact, impacted, impacting, impacts, effect, effected, effecting, effects, require, required, requires, requiring, respond, responded, responding, responds, responsive, change, changed, changes, changing, alter, altered, altering, alters, modified, modifies, modify, modifying, depend, depended, depending, depends, direct, directed, directing, directs, drive, driven, drives, driving, cause, caused, causes, causing, lead, leading, leads, led, target, targeted, targeting, targets, dependent, essential for regulation A process that changes the location of a material entity. YH, ZX translocation, transloated, translocating, translocates, migrated, migration, migrates migrating, mobilization, mobilize, mobilized, mobilizes, mobilizing, mobilisation, mobilise, mobilised, mobilises, mobilising translocation Any procedure or test to diagnose a disease or disorder. 2018-11-16T20:10:20Z NCIT:C18020 OGMS:0000104 diagnostic technique procedure diagnostic testing diagnostic procedure Use of a substance introduced into a living organism with therapeutic or diagnostic purpose. 2019-01-15T18:20:06Z CHEBI:52217 drug therapy drug treatment medication therapy pharmaceutical drug pharmaceutical treatment pharmacological treatment treatment with drug Medical treatment by means of drugs. pharmacotherapy Treatment with medications to improve cognition and function for patients with dementia. 2019-01-22T18:00:43Z antidementia drug therapy antidementia medication treatment antidementia agent therapy Use of a drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. 2019-01-22T18:13:06Z CHEBI:35554 NCIT:C78274 agent affecting cardiovascular system therapy cardiovascular agent drug treatment cardiovascular drug therapy cardiovascular drug treatment therapy cardiovascular system agent therapy cardiovascular system drug therapy treatment with cardiovascular agent treatment with cardiovascular drug treatment with cardiovascular medication treatment with cardiovascular therapy treatment with heart agent treatment with heart drug treatment with heart medication cardiovascular agent therapy They are a group of drugs that block the normal breakdown of acetylcholine (ACh) into acetate and choline and thereby increase both the levels and duration of actions of acetylcholine found in the central and peripheral nervous system. 2019-01-22T18:32:56Z CHEBI:37733 EC 3.1.1.8 (cholinesterase) inhibitor therapy cholinesterase inhibitor drug treatment cholinesterase inhibitor medication therapy treatment with EC 3.1.1.8 (cholinesterase) inhibitor Neurogenerative diseases such as Alzheimer disease, Parkinson disease, and Lewy body dementia are indications for cholinesterase inhibitor therapy. cholinesterase inhibitor therapy A measurement performed in a clinical setting using clinician's observations and instrument data to inform patient care and research. 2020-01-21T20:29:43Z CMO:0000000 PMID:2647562 clinical measurement clinical assessment 2020-05-28T19:11:27Z CHEBI:52206 biochemical role therapy treatment with biochemical role molecular pathway modifying agent therapy A therapy using a compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. 2020-06-02T18:44:24Z CHEBI:23924 enzyme inhibitor drug treatment enzyme inhibitor medication treatment enzyme inhibitor therapy treatment with enzyme inhibitor treatment with enzyme inhibitor agent treatment with enzyme inhibitor drug treatment with enzyme inhibitor medication treatment with enzyme inhibitor therapy enzyme inhibitor agent therapy Use of a drug that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. 2020-06-04T17:31:19Z CHEBI:147289 NCIT:C247 Treatment with ACE inhibitor Treatment with angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitor therapy ACE inhibitor therapy Use of a drug that inhibits angiotensin-converting enzyme (ACE) 1, an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. 2020-06-04T18:03:38Z CHEBI:35457 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor therapy Treatment with ACE-1 inhibitor Treatment with ACE1 inhibitor angiotensin-converting enzyme-1 inhibitor therapy peptidyl-dipeptidase A inhibitor therapy treatment with EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor treatment with angiotensin I-converting enzyme inhibitor ACE 1 inhibitor therapy Use of a drug that inhibits angiotensin-converting enzyme (ACE) 2, an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. 2020-06-04T18:17:34Z EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor therapy Treatment with ACE-2 inhibitor angiotensin-converting enzyme-2 inhibitor therapy angiotensin-converting enzyme2 inhibitor therapy treatment with EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor treatment with hACE2 inhibitor ACE 2 inhibitor therapy Therapy that inhibits HMG-CoA reductase inhibitor. 2020-11-17T21:37:04Z EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor therapy hydroxymethylglutaryl-CoA reductase inhibitor therapy statin agent therapy treatment with EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor treatment with statins HMG-CoA reductase inhibitor therapy A mental illness can be defined as a health condition that changes a person's thinking, feelings, or behavior (or all three) and that causes the person distress and difficulty in functioning. http://www.jbiomedsem.com/content/1/1/10 pathological mental process A mental illness can be defined as a health condition that changes a person's thinking, feelings, or behavior (or all three) and that causes the person distress and difficulty in functioning. https://www.ncbi.nlm.nih.gov/books/NBK20369/ A mental process that creates, modifies or has as participant some cognitive representation. cognitive process GO:0050890, cognition, defined as `The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.' A member of the species Homo Sapiens. person human being A mental process is a bodily process that is of a type such that it can of itself be conscious. Examples include thinking, feeling pain, remembering and emotion as occurrent experiences. A bodily process which brings into being, sustains or modifies a cognitive representation or a beahvior inducing state. mental process GO:0050890, cognition, defined as `The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.' A mental disposition is a bodily disposition that is realized in a mental process. mental disposition Irreversible introduction of a hydroxyl group that can affect K,P,Y or R residues. Hydroxylation is the first step in the oxidative degeneration of organic compounds. hydroxylation PSI-MI MI:0210 hydroxylation reaction Covalent attachment of palmitic acid to the cysteine residues of membrane proteins. Reversible reaction that can affect C,K,T or S residues. palmitoylation PSI-MI MI:0216 palmitoylation reaction terms aiming to represent biochemical reactions referring to their resulting product modifications. Biochemical reaction PSI-MI MI:0414 enzymatic reaction Molecule catalyzing a modification on its interacting partner. PSI-MI MI:0501 enzyme Decarboxylation is a chemical reaction that releases carbon dioxide (CO2). Usually, decarboxylation refers to a reaction of carboxylic acids, removing a carbon atom from a carbon chain. Enzymes that catalyze decarboxylations are called decarboxylases or, the more formal term, carboxy-lyases (EC number 4.1.1). orchard 2012-01-03T03:31:42Z decarboxylation PSI-MI MI:1140 decarboxylation reaction The manner, procedure or technique by which a morphological or physiological state or property in a single individual or sample or a group of individuals or samples is assessed and a quantitative or qualitative value assigned. measurement_method_ontology MMO:0000000 measurement method Detection of gamma rays emitted from tissues after administration of natural biochemical substance into which positron emitting isotopes have been incorporated. The paths of the gamma rays resulting from collision of positrons and electrons are interpreted by a computer to form a representation of local concentrations of the isotope-containing substance. mshimoyama 2010-08-05T02:27:10Z measurement_method_ontology PET scan MMO:0000129 positron emission tomography (PET) A method for identifying molecules based on the detection of the mass-to-charge ratio of ions generated from the molecule by vaporisation and electron bombardment. Deflection of the ions through a magnetic field results in a characteristic pattern which is used to define the molecule of interest. JSmith 2014-06-05T14:49:06Z OBI:0000470 mass spec measurement_method_ontology MMO:0000534 mass spectrometry A protein modification that oxygenates an L-methionine residue to one of the diastereomeric L-methionine sulfoxide residues. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-amino-4-[(R)-methylsulfinyl]butanoic acid L-methionine (R)-S-oxide L-methionine (R)-sulfoxide L-methionine S-oxide L-methionine sulfoxide MOD_RES Methionine sulfoxide MetO Methionyl Sulfoxide oxym PSI-MOD Oxidation MOD:00719 From DeltaMass: Average Mass: 147 Formula:C5H9O1N2S Monoisotopic Mass Change:147.035 Average Mass Change:147.195 (formula incorrect, N and O reversed) References:PE Sciex. L-methionine sulfoxide Any abnormality, anatomical or biochemical, evident at birth or during the neonatal period. DOID:0080015 EFO:0003915 ICD10:Q00.Q99 ICD9:759.89 ICD9:759.9 MESH:D000013 NCIT:C2849 SCTID:276654001 UMLS:CN232116 SCONG birth defect congenital Abnormality congenital abnormality congenital anatomic Abnormality congenital anatomical Abnormality congenital anomalies of fetus congenital anomaly congenital anomaly or birth defect congenital defect congenital defect/deformity congenital deformity congenital malformation defect/deformity, Congenital defect/deformity, congenital deformity/defect, Congenital physical disorder CM - congenital malformation fetal developmental abnormality fetal malformation foetal malformation MONDO:0000839 congenital abnormality The use of alcoholic beverages to excess, either on individual occasions ("binge drinking") or as a regular practice. COHD:433753 DOID:1574 ICD10:F10.1 ICD9:305.0 ICD9:305.00 MESH:D000437 SCTID:15167005 alcohol abuse ethanol abuse abuse, alcohol addiction, alcohol alcohol addiction alcohol dependence alcohol use disorder alcoholic intoxication, chronic alcoholism chronic alcoholic intoxication dependence, alcohol intoxication, chronic alcoholic MONDO:0002046 alcohol abuse An active inflammatory process affecting the liver for more than six months. Causes include viral infections, autoimmune disorders, drugs, and metabolic disorders. DOID:2237 EFO:0008496 ICD10:K73.9 ICD9:570 ICD9:571.4 ICD9:571.40 ICD9:571.41 MESH:D006505 NCIT:C3095 SCTID:197268000 Hepatitis hepatitis inflammation of liver liver inflammation acute and subacute liver necrosis acute hepatitis acute/subac. necrosis of liver animal hepatitis chronic hepatitis chronic persistent hepatitis Hepatitides MONDO:0002251 hepatitis A disease or disorder that involves the digestive system. COHD:4201745 DOID:77 EFO:0000405 ICD10:K92.9 ICD9:520-579.99 ICD9:V47.3 MESH:D005767 NCIT:C2990 SCTID:53619000 alimentary system disease digestive disease digestive system disease digestive system disease or disorder digestive system disorder disease of digestive system disease or disorder of digestive system disorder of digestive system gastroenterological system disease gastroenterological system disorder gastroenteropathy gastrointestinal disease gastrointestinal disorder gastrointestinal system disease gastrointestinal system disorder git disease stomach or intestinal disorder MONDO:0004335 digestive system disease A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization. COHD:201820 DOID:9351 EFO:0000400 HP:0000819 ICD10:E08-E13 ICD10:E10.E14 ICD10:E11 ICD9:250 MESH:D003920 NCIT:C2985 SCTID:73211009 UMLS:C0011847 UMLS:C0011849 DM diabetes diabetes mellitus MONDO:0005015 diabetes mellitus (disease) A disease involving the endocrine system. DOID:28 EFO:0001379 ICD10:E34.9 ICD9:259.8 ICD9:259.9 MESH:D004700 NCIT:C3009 SCTID:362969004 UMLS:C0014130 disease of endocrine system disease or disorder of endocrine system disorder of endocrine system endocrine disease endocrine disorder endocrine system disease endocrine system disease or disorder endocrine system disorder endocrinopathy thyroid or other glandular disorders MONDO:0005151 endocrine system disease early-onset familial form of Alzheimer disease DOID:0080348 GARD:0009465 OMIM:104300 UMLS:C2931257 AD AD1 Alzheimer disease Alzheimer disease 1 Alzheimer disease, early-onset, with cerebral amyloid angiopathy Alzheimer disease, familial, 1 Alzheimer disease, protection against presenile and senile dementia MONDO:0007088 Alzheimer disease type 1 https://rarediseases.info.nih.gov/diseases/9465/alzheimer-disease-type-1 An Alzheimer's disease that is characterized by an association of the apolipoprotein E E4 allele. DOID:0110035 GARD:0009467 ICD10:G30 MESH:C536595 OMIM:104310 UMLS:C1863051 AD2 Alzheimer disease 2 Alzheimer disease 2, late onset Alzheimer disease associated with APOE4 Alzheimer disease type 2 Alzheimer disease-2 Alzheimer's disease 2 Alzheimer's disease type 2 Alzheimer disease 2, late-onset Alzheimer disease associated with APOE E4 Alzheimer disease associated with Apoe4 LOFAD late onset Alzheimer disease late onset familial Alzheimer disease MONDO:0007089 Alzheimer disease 2 OMIM:269800 senile plaque formation MONDO:0010022 senile plaque formation An Alzheimer's disease that is characterized by an associated with a risk allele in in the PCDH11X gene on chromosome Xq21.3. DOID:0110036 MESH:C567463 OMIM:300756 UMLS:C2677888 AD16 Alzheimer disease 16 Alzheimer's disease 16 Alzheimer's disease type 16 MONDO:0010422 Alzheimer disease 16 OMIM:502500 Alzheimer disease, susceptibility to, mitochondrial MONDO:0010783 Alzheimer disease, susceptibility to, mitochondrial DOID:0110037 ICD10:G30 MESH:C566578 OMIM:602096 UMLS:C1865868 AD5 Alzheimer disease 5 Alzheimer disease type 5 Alzheimer disease, familial 5 Alzheimer's disease type 5 Ad5 Alzheimer disease, familial, 5 Alzheimer's disease 5 MONDO:0011194 Alzheimer disease 5 DOID:0110048 GARD:0007190 ICD10:G30 MESH:C536599 MESH:C566998 OMIM:604154 OMIM:611155 UMLS:C1858751 UMLS:C1970143 AD15 Alzheimer disease 15 Alzheimer disease without neurofibrillary tangles Alzheimer's disease 15 Alzheimer's disease type 15 Alzheimer's disease without neurofibrillary tangles MONDO:0011401 Alzheimer disease without neurofibrillary tangles MESH:C565728 OMIM:605055 UMLS:C1857933 Alzheimer disease, familial early-onset, with coexisting amyloid and prion pathology MONDO:0011513 Alzheimer disease, familial early-onset, with coexisting amyloid and prion pathology An Alzheimer's disease that is characterized by an associated with variation in the region 10q24. DOID:0110038 ICD10:G30 MESH:C565325 OMIM:605526 AD6 Alzheimer disease 6 Alzheimer disease 6, late onset Alzheimer disease type 6 Alzheimer's disease 6 Alzheimer's disease type 6 Alzheimer disease 6, late-onset plasma Beta-amyloid-42 level quantitative trait locus MONDO:0011561 Alzheimer disease 6 An Alzheimer's disease that is characterized by an associated with variation in the region 10p13. DOID:0110039 ICD10:G30 MESH:C565251 OMIM:606187 UMLS:C1853555 AD7 Alzheimer disease 7 Alzheimer disease type 7 Alzheimer disease, familial 7 Alzheimer's disease 7 Alzheimer's disease type 7 Ad7 Alzheimer disease, familial, 7 MONDO:0011647 Alzheimer disease 7 Alzheimer's disease with an early onset (starts before the age of 65). It is caused by mutations in the PSEN2 gene. DOID:0110040 GARD:0009469 MESH:C536596 NCIT:C123413 OMIM:606889 UMLS:C1847200 AD4 Alzheimer disease 4 Alzheimer disease type 4 Alzheimer disease, familial4 Alzheimer's disease 4 Alzheimer's disease type 4 familial Alzheimer disease, type 4 familial Alzheimer's disease, type 4 Ad4 Alzheimer disease familial type 4 Alzheimer disease, familial, 4 MONDO:0011743 Alzheimer disease 4 An Alzheimer's disease that is characterized by an associated with variation in the region 20p12.2-q11.21. DOID:0110041 ICD10:G30 MESH:C564622 OMIM:607116 UMLS:C1846735 AD8 Alzheimer disease 8 Alzheimer disease type 8 Alzheimer disease, familial 8 Alzheimer's disease 8 Alzheimer's disease type 8 Ad8 Alzheimer disease, familial, 8 MONDO:0011777 Alzheimer disease 8 Alzheimer's disease with an early onset (starts before the age of 65). It is caused by mutations in the PSEN1 gene. DOID:0110042 GARD:0009468 MESH:C536598 NCIT:C123412 OMIM:607822 AD3 Alzheimer disease 3 Alzheimer disease 3, early onset Alzheimer disease familial 3 Alzheimer disease type 3 Alzheimer's disease 3 Alzheimer's disease type 3 PSEN1 early-onset autosomal dominant Alzheimer disease early-onset autosomal dominant Alzheimer disease caused by mutation in PSEN1 familial Alzheimer disease, type 3 familial Alzheimer's disease, type 3 AD Alzheimer disease 3, early-onset Alzheimer disease early onset type 3 Alzheimer disease, familial, 3 Alzheimer disease, familial, 3, with spastic paraparesis and apraxia Alzheimer disease, familial, 3, with spastic paraparesis and unusual plaques MONDO:0011913 Alzheimer disease 3 An Alzheimer's disease that is characterized by an associated with variation in the region 7q36. DOID:0110043 ICD10:G30 MESH:C566465 OMIM:609636 UMLS:C1864828 AD10 Alzheimer disease 10 Alzheimer disease familial 10 Alzheimer disease type 10 Alzheimer's disease 10 Alzheimer's disease type 10 Ad10 Alzheimer disease, familial, 10 MONDO:0012321 Alzheimer disease 10 An Alzheimer's disease that is characterized by an associated with variation in the region 9p22.1. DOID:0110044 ICD10:G30 MESH:C565228 OMIM:609790 UMLS:C1853360 AD11 Alzheimer disease 11 Alzheimer disease type 11 Alzheimer's disease 11 Alzheimer's disease type 11 Ad11 Alzheimer disease, familial, 11 MONDO:0012344 Alzheimer disease 11 An Alzheimer's disease that is characterized by an associated with variation in the region 8p12-q22. DOID:0110045 ICD10:G30 MESH:C567022 OMIM:611073 UMLS:C1970209 AD12 Alzheimer disease 12 Alzheimer disease familial 12 Alzheimer disease type 12 Alzheimer's disease 12 Alzheimer's disease type 12 Ad12 Alzheimer disease, familial, 12 MONDO:0012609 Alzheimer disease 12 An Alzheimer's disease that is characterized by an associated with variation in the region 1q21. DOID:0110046 ICD10:G30 MESH:C567000 OMIM:611152 UMLS:C1970147 AD13 Alzheimer disease 13 Alzheimer's disease 13 Alzheimer's disease type 13 MONDO:0012630 Alzheimer disease 13 An Alzheimer's disease that is characterized by an associated with variation in the region 1q25. DOID:0110047 ICD10:G30 MESH:C566999 OMIM:611154 UMLS:C1970144 AD14 Alzheimer disease 14 Alzheimer's disease 14 Alzheimer's disease type 14 MONDO:0012631 Alzheimer disease 14 An Alzheimer's disease that is characterized by an associated with mutations in the gene TREM2. DOID:0110049 OMIM:615080 UMLS:C3554452 AD17 Alzheimer disease 17 Alzheimer disease 17, late onset Alzheimer's disease 17 Alzheimer's disease type 17 Alzheimer disease 17, late-onset MONDO:0014036 Alzheimer disease 17 Any Alzheimer disease in which the cause of the disease is a mutation in the ADAM10 gene. DOID:0110050 OMIM:615590 UMLS:C3810041 AD18 ADAM10 Alzheimer disease Alzheimer disease 18 Alzheimer disease caused by mutation in ADAM10 Alzheimer disease type 18 Alzheimer's disease 18 Alzheimer's disease type 18 Alzheimer disease 18, late-onset MONDO:0014265 Alzheimer disease 18 Any Alzheimer disease in which the cause of the disease is a mutation in the PLD3 gene. DOID:0110051 OMIM:615711 UMLS:C3810349 AD19 Alzheimer disease 19 Alzheimer disease 19 late onset Alzheimer disease caused by mutation in PLD3 Alzheimer disease type 19 Alzheimer's disease 19 Alzheimer's disease type 19 PLD3 Alzheimer disease Alzheimer disease 19, late-onset MONDO:0014316 Alzheimer disease 19 Early-onset autosomal dominant Alzheimer disease (EOAD) is a progressive dementia with reduction of cognitive functions. EOAD presents the same phenotype as sporadic Alzheimer disease (AD) but has an early age of onset, usually before 60 years old. GARD:0012798 ICD10:G30.0 Orphanet:1020 UMLS:CN043596 EOFAD early-onset familial autosomal dominant Alzheimer disease early-onset, autosomal dominant Alzheimer disease MONDO:0015140 early-onset autosomal dominant Alzheimer disease Corticobasal syndrome (CBS) is a rare neurodegenerative disease characterized by multifaceted motor system dysfunctions and cognitive defects such as asymmetric rigidity, bradykinesia, limb apraxia, and visuospatial dysfunction. ICD10:G31.0 Orphanet:454887 UMLS:CN237765 MONDO:0018696 corticobasal syndrome SCTID:18842008 corticobasal degeneration cortical basal ganglionic degeneration corticodentatonigral degeneration with neuronal achromasia MONDO:0022880 corticobasal degeneration A broad grouping of diseases based on major body subdivisions. SCTID:123946008 UMLS:C1290853 disease by body site disease of organism subdivision disorder by body site disorder of anatomical disorder of organism subdivision MONDO:0024505 disorder by anatomical region A degenerative disease of the brain that causes gradual loss of memory, judgment, and the ability to function socially. About 25% of all Alzheimer disease is familial (more than 2 people in a family have AD). When Alzheimer disease begins before 60 or 65 years of age (early-onset AD) about 60% of the cases are familial (also known as Early-onset familial AD). These cases appear to be inherited in an autosomal dominant manner. http://orcid.org/0000-0001-5208-3432 Alzheimer disease, familial FAD GARD:0000632 MONDO:0100087 familial Alzheimer disease A form of familial Alzheimer disease, that begins after age 65. GARD:0012799 Alzheimer disease type 2 MONDO:0100088 late-onset familial alzheimer disease Formation of a covalent bond between a substrate and an acetyl group. acetylation MOP:0000030 has_participant: CHEBI:40574 acetylation A process in which at least one of the participants is a molecule. MOP:0000543 TODO: needs work, formal definition, etc. molecular process The formation of at least two single bonds between a metal atom and a ligand. batchelorc 2009-08-14T09:55:35Z metal ion chelation MOP:0000604 metal chelation Breaking of a covalent bond between a substrate and an amino group. MOP:0000651 deamination A molecular process in which a covalent bond is formed. MOP:0000779 formation of covalent bond Breaking of a covalent bond between a substrate and an acetyl group. MOP:0001030 has_participant: CHEBI:40574 deacetylation Breaking of a covalent bond between a substrate and a carbonyl group. MOP:0001494 has_participant: CHEBI:23019 decarbonylation A reduction in size of organs or tissues as a result of cell death, loss of cellularity of whatever cause, reduced cellular proliferation or decreased cellular volume. mouse_pathology.ontology MPATH:127 atrophy Energy dependent cell death induced by intrinsic genetic or developmental programme, or external stimuli such as addition or withdrawal of cytokines or trophic factors, radiation, chemotherapeutic agents etc. Characterised by cell shrinkage, increases in membrane permeability, endonucleolyis and nuclear fragmentation resulting in the formation of rapidly endocytosed apoptotic bodies. mouse_pathology.ontology programmed cell death MPATH:3 apoptosis The organic response of tissues to external insult, injury or underlying genetic or epigenetic lesion. mouse_pathology.ontology MPATH:596 pathological process a partial absence or patchy, incomplete area of a myelin sheath over all or part of an axon or fiber tract due to degeneration or destruction of the myelin sheath MP:0010049 myelin degeneration myelin destruction MPheno.ontology MP:0000921 Demyelination is a term used to describe the destruction of the myelin sheath that surrounds axonal fibres. This is caused by diseases that damage the myelin sheath or the cells that form it. demyelination inflammation of any blood and/or lymphatic vessel vessel inflammation MPheno.ontology MP:0001864 vascular inflammation condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma MPheno.ontology increased ROS production increased reactive oxygen species production MP:0003674 oxidative stress diminished effectiveness of insulin in lowering plasma glucose levels MPheno.ontology MP:0005331 insulin resistance any anomaly in the concentration of the subclass of sphingoid base derivatives with an amide-linked fatty acid, where the fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms csmith 2013-11-11T15:00:49Z MPheno.ontology MP:0012232 abnormal ceramide level "Behavior related to the complex psychophysiological experience of an individual's state of mind as interacting with biochemical (internal) and environmental (external) influences." [wikipedia:Emotions] 2011-04-14T01:03:39Z George Gkoutos affective behaviour mood behavior_ontology emotional behavior "A behavior that occur quickly without control, planning, or consideration of the consequences of that behavior." [NBO:GVG] 2011-03-31T11:08:55Z George Gkoutos behavior_ontology impulsive behavior "The action, reaction, or performance of an organism in response to external or internal stimuli." [GO:GO\:0007610] 2011-04-05T09:53:10Z George Gkoutos NBO:0000000 behavior behaviour behavior_ontology GO:0007610 behavior process "Behaviour related to cognitive processes." [NBO:JH] 2011-04-14T03:51:13Z George Gkoutos behavior_ontology cognitive behavior "Behavior related to the intake of substances." [NBOC:GVG] George Gkoutos ingest consumption behavior "Behavior related to the intake of nicotine." [NBOC:GVG] George Gkoutos nicotine consumption GC_ID:1 ncbi_taxonomy all root GC_ID:1 rat rats ncbi_taxonomy Rattus A cellular organism is an organism that contains one or more cells. GC_ID:1 ncbi_taxonomy biota cellular organisms A cellular organism is an organism that contains one or more cells. http://semanticscience.org/resource/SIO_010377 GC_ID:1 turmeric ncbi_taxonomy Curcuma domestica Curcuma longa GC_ID:1 ncbi_taxonomy herbal medicine One of the three domains of life (the others being bacteria and archea), also called Eukarya. These are organisms whose cells are enclosed in membranes and possess a nucleus. They comprise almost all multicellular and many unicellular organisms, and are traditionally divided into groups (sometimes called kingdoms) including Animals; plants; fungi; and various algae and other taxa that were previously part of the old kingdom Protista. GC_ID:1 PMID:23020233 PMID:30257078 eucaryotes eukaryotes ncbi_taxonomy Eucarya Eucaryotae Eukarya Eukaryotae eukaryotes Eukaryota One of the three domains of life (the others being bacteria and archea), also called Eukarya. These are organisms whose cells are enclosed in membranes and possess a nucleus. They comprise almost all multicellular and many unicellular organisms, and are traditionally divided into groups (sometimes called kingdoms) including Animals; plants; fungi; and various algae and other taxa that were previously part of the old kingdom Protista. http://tolweb.org/Eukaryotes NCBITaxon:488673 GC_ID:1 ginkgo maidenhair tree ncbi_taxonomy Ginkgo biloba f. epiphylla Ginkgo biloba var. epiphylla Ginkgo biloba GC_ID:1 lavenders ncbi_taxonomy Lavandula Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young. GC_ID:1 mammals ncbi_taxonomy mammals Mammalia Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young. https://www.ncbi.nlm.nih.gov/mesh/D008322 GC_ID:1 roundworm ncbi_taxonomy Rhabditis elegans Caenorhabditis elegans NCBITaxon:7326 GC_ID:1 Drosophila fruit flies fruit fly ncbi_taxonomy Drosophila <flies,genus> Animals having a vertebral column, members of the phylum Chordata, subphylum Craniata comprising mammals, birds, reptiles, amphibians, and fishes. GC_ID:1 Vertebrata vertebrates ncbi_taxonomy vertebrates Vertebrata <vertebrates> Animals having a vertebral column, members of the phylum Chordata, subphylum Craniata comprising mammals, birds, reptiles, amphibians, and fishes. https://www.ncbi.nlm.nih.gov/mesh/D014714 NCBITaxon:27702 NCBITaxon:37966 GC_ID:1 leopard danio zebra danio zebra fish zebrafish ncbi_taxonomy Brachydanio rerio Brachydanio rerio frankei Cyprinus rerio Danio frankei Danio rerio frankei Danio rerio The primate species of mammal to which modern humans belong. GC_ID:1 human man ncbi_taxonomy Home sapiens Homo sampiens Homo sapeins Homo sapian Homo sapians Homo sapien Homo sapience Homo sapiense Homo sapients Homo sapines Homo spaiens Homo spiens Humo sapiens Homo sapiens The primate species of mammal to which modern humans belong. https://www.medicinenet.com/script/main/art.asp?articlekey=40191 The CDISC version of the Alzheimer's Disease Assessment Scale-Cognitive (CDISC ADAS-Cog) containing 15 summary-level tests. This version is based on combining the total pool of ADAS-Cog tests that were observed during a review of multiple case report forms administered in clinical trials of Alzheimer's disease, as well as the CRF administered in the Alzheimer's Disease Neuroimaging Initiative (ADNI) observational study. (Modified from Mohs RC, Rosen WG, Davis KL. The Alzheimer's disease assessment scale: an instrument for assessing treatment efficacy. Psychopharmacol Bull 1983;19(3):448-450. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984;141(11):1356-1364. Mohs RC, Knopman D, Petersen RC et al. Development of cognitive instruments for use in clinical trials of antidementia drugs: additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord 1997;11 Suppl 2:S13-S21. Wouters H, van Gool WA, Schmand B, Lindeboom R. Revising the ADAS-cog for a more accurate assessment of cognitive impairment. Alzheimer Dis Assoc Disord 2008;22(3):236-244.). C100762 Intellectual Product Alzheimer's Disease Assessment Scale-Cognitive CDISC Version Questionnaire C3539026 CDISC The CDISC version of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog CDISC Version) containing 15 summary-level tests. This version is based on combining the total pool of ADAS-Cog tests that were observed during a review of multiple case report forms administered in clinical trials of Alzheimer's disease, as well as the CRF administered in the Alzheimer's Disease Neuroimaging Initiative (ADNI) observational study. (Modified from Mohs RC, Rosen WG, Davis KL. The Alzheimer's disease assessment scale: an instrument for assessing treatment efficacy. Psychopharmacol Bull 1983;19(3):448-450. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984;141(11):1356-1364. Mohs RC, Knopman D, Petersen RC et al. Development of cognitive instruments for use in clinical trials of antidementia drugs: additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord 1997;11 Suppl 2:S13-S21. Wouters H, van Gool WA, Schmand B, Lindeboom R. Revising the ADAS-cog for a more accurate assessment of cognitive impairment. Alzheimer Dis Assoc Disord 2008;22(3):236-244.). ADAS-COG ADC Alzheimer's Disease Assessment Scale-Cognitive CDISC Version Questionnaire Alzheimer's Disease Assessment Scale-Cognitive CDISC Version Questionnaire A standardized rating scale developed by John C. Morris in 1997 to evaluate the severity of an individual's cognitive impairment. This instrument contains 6 areas which include memory, orientation, judgment and problem solving, community affairs, home and hobbies, and personal care. Each item is rated on a scale from 0 to 3 with 0 being none and 3 being severe. C102114 Intellectual Product Clinical Dementia Rating Questionnaire C0451074 CDISC Clinical Dementia Rating (CDR) (Morris, JC. Clinical Dementia Rating: A reliable and valid diagnostic and staging measure for dementia of the Alzheimer type. International Psychogeriatrics 1997: 9, Suppl. 1, 173-176). CDR CDR01 Clinical Dementia Rating Questionnaire Clinical Dementia Rating Questionnaire An imaging technique that utilizes positron emission tomography to produce a three-dimensional image of functional processes in the body. The system detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (tracer), which is introduced into the body on the biologically active molecule (fludeoxyglucose) FDG. FDG is an analogue of glucose which when imaged will give tissue metabolic activity, in terms of regional glucose uptake. C103400 Diagnostic Procedure FDG-Positron Emission Tomography FDG-Positron Emission Tomography C3641247 CTRP NCCN FDG-PET FDG-PET Imaging FDG-Positron Emission Tomography FDG-Positron Emission Tomography A standardized questionnaire developed by Gelinas et al in 1998, which is used to measure the changes in functional activities in patients with Alzheimer's disease. The questionnaire contains 40 items across 3 domains; basic activities of daily living, instrumental activities of daily living and leisure activities. C105165 Intellectual Product Disability Assessment for Dementia Questionnaire C3641946 CDISC Disability Assessment for Dementia (DAD) (copyright 1994 by L. Gauthier I. Gelinas. All rights reserved.). DAD DAD01 Disability Assessment for Dementia Questionnaire Disability Assessment for Dementia Questionnaire A standardized questionnaire developed by Galasko et al in 1997 as part of the Alzheimer's disease cooperative study, which is used to measure the performance of activities of daily living by patients diagnosed with Alzheimer's disease. The questionnaire contains 23 items (and a number of sub-items within the 23 main items) with a range of preset answers that are assigned points based on performance. C105166 Intellectual Product Alzheimer's Disease Cooperative Study Activities of Daily Living Inventory Questionnaire C3641947 CDISC Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory (ADCS-ADL) (Galasko, D., Bennett, D., Sano, M., Ernesto, C., Thomas, R., Grundman, M., Ferris, S., and the ADCS. "An Inventory to Assess Activities of Daily Living for Clinical Trials in Alzheimer's Disease." Alzheimer's Disease and Associated Disorders, 1997. Volume 11(2): S33-S39). ADCS-ADL ADL01 Alzheimer's Disease Cooperative Study Activities of Daily Living Inventory Questionnaire Alzheimer's Disease Cooperative Study Activities of Daily Living Inventory Questionnaire A standardized rating scale developed by Yesavage et al in 1983, which is a self-report assessment used to identify depression in older adults. The questionnaire contains 30 items. All questions are answered 'yes' or 'no'. C106697 Intellectual Product Geriatric Depression Scale Questionnaire C0451184 CDISC Geriatric Depression Scale (GDS) (Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatry Res. 1983;17(1):37-49). GDS GDS01 Geriatric Depression Scale Questionnaire Geriatric Depression Scale Questionnaire A standardized questionnaire developed by Galasko et al in 1997 as part of the Alzheimer's disease cooperative study, which is used to measure the performance of activities of daily living by patients diagnosed with Alzheimer's disease, exhibiting evidence of mild cognitive impairment (MCI). The questionnaire contains 24 items (and a number of sub-items within the 24 main items) with a range of preset answers that are assigned points based on performance. C106888 Intellectual Product Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory Mild Cognitive Impairment Questionnaire C3827035 CDISC Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory (ADCS-ADL), MCI Version (Galasko, D., Bennett, D., Sano, M., Ernesto, C., Thomas, R., Grundman, M., Ferris, S., and the ADCS. An Inventory to Assess Activities of Daily Living for Clinical Trials in Alzheimer's Disease. Alzheimer's Disease and Associated Disorders, 1997. Volume 11(2): S33-S39). ADCS-ADL MCI ADL03 Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory Mild Cognitive Impairment Questionnaire Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory Mild Cognitive Impairment Questionnaire The free carboxy-terminal intracellular domain (ICD) of a notch family protein, which is a product of regulated intramembrane proteolysis mediated by the gamma-secretase enzyme complex. This protein fragment is involved in transcriptional regulation of target genes. C111794 Amino Acid, Peptide, or Protein Notch Receptor Intracellular Domain C3828777 Full-length notch proteins are post-translationally cleaved by furin to produce a disulfide bound, two-chain protein that is expressed on the cell surface. Once a notch ligand binds the extracellular portion, the larger amino-terminal portion is released from the cell surface and the remaining portion of the receptor, termed the Notch extracellular truncated (NEXT) domain is endocytosed. During endocytosis, NEXT is cleaved sequentially by an ADAM family secretase followed by intramembrane cleavage by gamma-secretase, which allows the notch intracellular domain to dissociate from the membrane and translocate into the nucleus. NICD Neurogenic Locus Notch Homolog Protein ICD Neurogenic Locus Notch Homolog Protein Intracellular Domain Notch ICD Notch Intracellular Domain Notch Receptor Intracellular Domain Notch Receptor Intracellular Domain An application of functional MRI used to measure cerebral blood flow. ASL uses magnetically labeled water as the tracer. C116450 Diagnostic Procedure Arterial Spin Labeling Magnetic Resonance Imaging Arterial Spin Labeling Magnetic Resonance Imaging CL446664 CDISC CTRP A noninvasive fMRI technique that uses arterial water as an endogenous tracer to measure cerebral blood flow by magnetically labeling the proton spins of the arterial water prior to reaching the imaged volume. ARTERIAL SPIN LABELING FUNCTIONAL MRI ASL ASL fMRI Arterial Spin Labeling MRI Arterial Spin Labeling Magnetic Resonance Imaging Arterial Spin Labeling Magnetic Resonance Imaging A standard from which a judgment concerning a medical diagnosis can be established. C117960 Idea or Concept Diagnostic Criteria C0679228 CDISC A standard from which a judgment concerning a medical diagnosis can be established. DXCRIT Diagnostic Criteria Diagnostic Criteria A standardized rating scale originally developed by Chouinard et al in 1980, which is used to measure drug-induced extrapyramidal symptoms (EPS) or 4 types of drug-induced movement disorders (DIMD): parkinsonism, akathisia, dystonia, and tardive dyskinesia. The questionnaire contains 28 questions and generates 4 subscales and 4 clinical global impression severity (CGI-S) scales. C117997 Intellectual Product Extrapyramidal Symptom Rating Scale-Abbreviated Clinical Classification C3896675 CDISC Extrapyramidal Symptom Rating Scale-Abbreviated (ESRS-A) (Copyright 2006 Larry Alphs, MD, PhD, Guy Chouinard, MD, All Rights Reserved). ESRS-A ESRSA ESRSA1 Extrapyramidal Symptom Rating Scale-Abbreviated Clinical Classification Extrapyramidal Symptom Rating Scale-Abbreviated Clinical Classification A protein complex that plays a role in both NMDA binding and ion transport. It is a heterotetramer consisting of 2 glutamate [NMDA] receptor subunit zeta-1 proteins and 2 epsilon subunits (glutamate [NMDA] receptor subunit epsilon-1, -2, -3 or -4). C118457 Amino Acid, Peptide, or Protein N-Methyl-D-Aspartate Receptor C0080093 N-Methyl-D-Aspartate Receptor N-Methyl-D-aspartate receptor NMDA Receptor NMDAR N-Methyl-D-Aspartate Receptor A subfamily within the forkhead box (FOX) protein family, which is a family of transcription factors that contain a forkhead DNA-binding domain. FOXO proteins regulate apoptosis, cell-cycle progression, oxidative-stress resistance, and tumor suppression. The transcriptional promoter activity of these factors is regulated by post-translational modifications, such as phosphorylation, acetylation, and monoubiquitination. C118892 Amino Acid, Peptide, or Protein FOXO Family FOXO Family C3899164 CTRP There are four known members of the FOXO family expressed in humans. They are FOXO1, FOXO3, FOXO4 and FOXO6. FOXO FOXO Family Fork Head Box Transcription Factor Class O Forkhead Box Transcription Factor Class O FoxO FOXO Family A phospholipid that is a component of the plasma membrane with signal transduction inducing activity. Phosphatidylinositol 4,5-bisphosphate (PIP2) is an intermediate that can be converted into either the second messenger signaling molecules, inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), or phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P3; PIP3). Both PIP2 and PIP3 can act as docking phospholipids, which recruit signaling proteins to the plasma membrane and promotes the activation of several signaling cascades. C1192 Biologically Active Substance Organic Chemical Phosphatidylinositol 4,5-bisphosphate C0070798 Phosphatidylinositol_4_5-bisphosphate CHEBI:18348 1,2-Diacyl-sn-Glycero-3-Phospho-(1'-myo-Inositol-4',5'-Bisphosphate) 1-O-(3-sn-Phosphatidyl)-1D-myo-Inositol 4,5-Bis(Dihydrogen Phosphate) 1-Phosphatidyl-1D-myo-Inositol 4,5-Bisphosphate 1-Phosphatidyl-D-myo-Inositol 4,5-Bisphosphate PIP2 PIPP Phosphatidyl-myo-Inositol 4,5-Bisphosphate Phosphatidylinositol 4,5-Diphosphate Phosphatidylinositol 4,5-bisphosphate PtdIns(4,5)P2 PtsIns-4,5-P2 Phosphatidylinositol 4,5-bisphosphate The second version of California Verbal Learning Test, a neuropsychological test developed to make a comprehensive and detailed assessment of verbal learning and memory in individuals ranging in age from 16 to 89 years. C120257 Intellectual Product California Verbal Learning Test - Second Edition C3899729 CVLT-II California Verbal Learning Test - Second Edition California Verbal Learning Test 2nd Edition California Verbal Learning Test II California Verbal Learning Test, Second Edition California Verbal Learning Test - Second Edition A standardized rating scale developed by Ziad Nasreddine in 1996 to screen for mild cognitive dysfunction and impairment. This instrument assesses the following cognitive domains: attention and concentration, executive functions, memory, language, visuoconstructional skills, conceptual thinking, calculations, and orientation. C123667 Intellectual Product Montreal Cognitive Assessment Functional Test C3496286 CDISC Montreal Cognitive Assessment (MoCA) (Copyright Z. Nasreddine MD. Ziad S. Nasreddine, Natalie A. Phillips, Valerie Bedirian, Simon Charbonneau, Victor Whitehead, Isabelle Collin, Jeffrey L. Cummings and Howard Chertkow. The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment. J Am Geriatr Soc. 2005 Apr;53(4):695-9). MOCA MOCA01 Montreal Cognitive Assessment Montreal Cognitive Assessment Functional Test Montreal Cognitive Assessment Functional Test A standardized rating scale modified from A. Rey in 1964 and Ceffen et al in 1994, which is used to evaluate verbal learning and memory abilities in both children and adults. The questionnaire contains 36 items and assesses overall memory performance, immediate span of memory for words, acquisition rate, interference effects, and recognition. C123668 Intellectual Product Rey Auditory Verbal Learning Functional Test C4054062 CDISC Auditory Verbal Learning Test (AVLT-Rey) (Modified from Rey A. L'examen clinique en psychologie [Clinical tests in psychology]. Paris: Presses Universitaires de France; 1964. Test-Retest Reliability of a New Form of Auditory Verbal Learning Test (AVLT); Archives of Clinical Neuropsycology, Vol. 9, No. 4, pp. 303-316, 1994. Performance of Healthy Subjects and Patients with Resection from the Anterior Temporal Lobe on Matched Tests of Verbal and Visuoperceptual Learning; Journal of Clinical and Experimental Neuropsychology 1996, Vol. 18, No. 3, pp. 416-430). AVL02 AVLT-REY Rey Auditory Verbal Learning Functional Test Rey Auditory Verbal Learning Functional Test A white blood cell that lacks cytoplasmic granules with an affinity for specific biological stains; typically, a lymphocyte, monocyte, or plasma cell. C12534 Cell Leukocyte, Mononuclear Non-Granular Leukocyte C0023517 A type of white blood cell. Monocytes and lymphocytes are agranulocytes. Non-Granular_Leukocyte Agranulocyte Mononuclear Leukocyte Non-Granular Leukocyte Non-Granular Leukocytes agranulocyte Non-Granular Leukocyte A question about whether an individual has or had difficulty in swallowing. C125410 Intellectual Product Have Difficulty Swallowing C4084787 CL972888 Difficulty swallowing Had Trouble Swallowing Have Difficulty Swallowing Have you had trouble swallowing Trouble Swallowing Have Difficulty Swallowing A question about whether an individual has or had indigestion. C125913 Intellectual Product Have Indigestion CL504562 Have Indigestion Have you had indigestion Have Indigestion A technique that monitors blood oxygen level dependent (BOLD) signals to map brain regions that active while not performing any specific task. C129326 Diagnostic Procedure Resting State Functional Connectivity Magnetic Resonance Imaging Resting State Functional Connectivity Magnetic Resonance Imaging CL512231 CTRP RS-fcMRI Resting State Functional Connectivity MRI Resting State Functional Connectivity Magnetic Resonance Imaging Resting fcMRI Resting State Functional Connectivity Magnetic Resonance Imaging A sub-family of the cysteine knot platelet-derived growth factor family. Members of the vascular endothelial growth factor (VEGF) family play a role in the promotion of embryonic vasculogenesis and the stimulation of angiogenesis during physiologic and pathologic processes. C129646 Amino Acid, Peptide, or Protein Vascular Endothelial Growth Factor Family Vascular Endothelial Growth Factor Family C1256770 CTRP There are five members of the VEGF family expressed in mammals: VEGF-A, placenta growth factor (PGF), VEGF-B, VEGF-C and VEGF-D. VEGF VEGF Family Vascular Endothelial Growth Factor Vascular Endothelial Growth Factor Family Vascular Endothelial Growth Factor Family This gene plays a role in both mitochondrial protein translation and apoptosis regulation. C131258 561010 Gene or Genome MT-RNR2 Gene C1537997 HGNC:7471 MT-RNR2 MT-RNR2 Gene Mitochondrially Encoded 16S RNA Gene MT-RNR2 Gene A question about how much difficulty an individual currently has learning new tasks or instructions. C137847 Intellectual Product Current Difficulty Learning New Tasks or Instructions C3261567 Current Difficulty Learning New Tasks or Instructions How much DIFFICULTY do you currently have learning new tasks or instructions Current Difficulty Learning New Tasks or Instructions The domesticated guinea pig, Cavia porcellus. C14211 Mammal Guinea Pig C0999699 CDISC The domesticated guinea pig, Cavia porcellus. (NCI) 10141 Guinea_Pig CAVIA PORCELLUS Cavia porcellus GUINEA PIG Guinea Pig Mammals, Guinea Pigs Guinea Pig A substance detectable in the blood that can be used to assess levels of inflammation in the body. C143955 Functional Concept Blood Inflammatory Marker CL542157 Blood Inflammatory Marker Blood Inflammatory Marker Protein found in the peripheral blood. C150129 Amino Acid, Peptide, or Protein Circulating Protein Circulating Protein CL551923 Circulating Protein Circulating Protein Research conducted with human subjects or on material of human origin in which an investigator directly interacts with human subjects; includes development of new technologies, study of mechanisms of human diseases, therapy, clinical trials, epidemiologic, behavior, and health services research. C15206 Research Activity Clinical Study C0008972 CDISC CDISC-GLOSS FDA ICDC A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. [ClinicalTrials.gov] See also clinical trial. A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. [ClinicalTrials.gov] See also clinical trial. (CDISC Glossary) Clinical_Study CLINICAL STUDY Clinical Research Clinical Studies Clinical Study Study clinical study study Clinical Study Therapy designed to induce changes in a patient's immune status in order to treat disease. C15262 Therapeutic or Preventive Procedure Immunotherapy Immunotherapy C0021083 CDISC CPTAC CTRP GDC PCDC A therapy designed to induce changes in a patient's immune status. Treatment to boost or restore the ability of the immune system to fight cancer, infections, and other diseases. Also used to lessen certain side effects that may be caused by some cancer treatments. Agents used in immunotherapy include monoclonal antibodies, growth factors, and vaccines. These agents may also have a direct antitumor effect. Immunotherapy Immunotherapy (Including Vaccines) The concept encompasses various treatment modalities including active and passive immunization, treatment with immunopotentiators, immunosuppressants and nonspecific systemic immunostimulators and adjuvants, desensitization to any allergens, bone marrow transplantation, thymus implantation. IMMUNOTHERAPY Immunological Immunological Therapy Immunologically Directed Therapy Immunotherapy immunotherapy Immunotherapy A study in which participants with no known disease are initially assessed, and then reassessed for the same characteristic at mutiple timepoints in the future. C15273 Research Activity Longitudinal Study C0023981 CDISC CDISC-GLOSS In medicine, a study or clinical trial in which participants are identified and then followed forward in time. Investigation in which data are collected from a number of subjects over a long period of time (a well-known example is the Framingham study). Studies that look forward using periodic observations collected predominantly following subject enrollment. (clinicaltrials.gov) Longitudinal_Study Longitudinal Study PROSPECTIVE longitudinal study prospective Longitudinal Study An invasive procedure in which a hollow needle is introduced through an intervertebral space in the lower back to access the subarachnoid space in order to sample cerebrospinal fluid or to administer medication. C15327 Diagnostic Procedure Lumbar Puncture C0037943 A procedure in which a thin needle called a spinal needle is put into the lower part of the spinal column to collect cerebrospinal fluid or to give drugs. Lumbar_Puncture LP Lumbar Puncture Spinal Tap lumbar puncture spinal tap Lumbar Puncture An uncontrolled observational study containing a detailed report of the diagnosis, treatment, and follow-up of an individual patient. Case reports also contain some demographic information about the patient (for example, age, gender, ethnic origin). C15362 Research Activity Case Study C0085973 CDISC A detailed report of the diagnosis, treatment, and follow-up of an individual patient. Case reports also contain some demographic information about the patient (for example, age, gender, ethnic origin). A study in which the subject with the condition under study (the case) is compared against a theoretical/historical model of distribution that serves as a control. Case_Study CASE ONLY Case Report Case Study case report Case Study A test of the ability of an individual to accurately place the numbers and hands of a clock in their usual and specified positions. C157012 Intellectual Product Cognition Clock Test CL936069 Cognition Clock Test Cognition Clock Test The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder. C15709 Laboratory Procedure Genetic Testing Genetic Testing C0679560 CTRP NICHD Analyzing DNA to look for a genetic alteration that may indicate an increased risk for developing a specific disease or disorder. Genetic_Testing Genetic Testing Genetic Examination Genetic Test Genetic Testing genetic analysis genetic testing Genetic Testing The systematic collection, analysis, and interpretation of health data on an ongoing basis. C15719 Health Care Activity Surveillance CL426379 In medicine, the ongoing collection of information about a disease, such as cancer, in a certain group of people. The information collected may include where the disease occurs in a population and whether it affects people of a certain gender, age, or ethnic group. Surveillance Epidemiology / Surveillance Surveillance surveillance Surveillance Cognitive, emotional, and behavioral difficulties that often occur in conjunction with frontal lobe disorders, including traumatic injury and dementia. It is also a feature of attention deficit disorder and other non-trauma-induced conditions. C160587 Mental or Behavioral Dysfunction Executive Function Disorder Executive Function Disorder CTRP EFD Executive Dysfunction Executive Function Disorder Executive Functioning Deficit Impairment of Executive Functions Executive Function Disorder Chromogranins are acidic secretory glycoproteins with a widespread but specific distribution in neuroendocrine tissues. The chromogranin family is heterogenous, consisting of propeptides such as chromogranin-A, chromogranin-B and secretogranin II, which can either elicit an effect themselves, or serve as precursors to a large number of peptides, which are biologically more active. C16436 Amino Acid, Peptide, or Protein Chromogranin C0008586 Chromogranin CHG Chromogranin Chromogranin Any method that uses a visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. C16502 Diagnostic Procedure Diagnostic Imaging Diagnostic Imaging C0011923 CTRP GDC Diagnostic_Imaging Diagnostic Imaging Diagnostic Imaging Medical Imaging Diagnostic Imaging Proteins that non-covalently interact with deoxyribonucleic acid as a result of intermolecular physical forces and spatial complementarity. Many genetic regulatory DNA binding proteins bind to double- or single-stranded DNA in a sequence-specific manner and share common structural motifs such as the zinc-finger, helix-turn-helix, and leucine zipper. C16518 Amino Acid, Peptide, or Protein DNA Binding Protein C0012940 DNA_Binding_Protein DNA Binding Protein DNA Binding Protein The genetic constitution of an organism or cell, as distinct from its expressed features or phenotype. C16631 Organism Attribute Genotype C0017431 At its broadest level, genotype includes the entire genetic constitution of an individual. It is often applied more narrowly to the set of alleles present at one or more specific loci. Genotype Genotype Genotypic genotype Genotype C166444 Amino Acid, Peptide, or Protein Aducanumab CL971693 105J35OE21 FDA ADUCANUMAB Aducanumab Aducanumab A family of highly-conserved proteins that are synthesized in response to hyperthermia (heat shock), hypoxia, or other stresses that appear to increase cellular thermal tolerance and enable cells to recover from stress. Some heat shock proteins may protect other proteins from denaturation, degradation or perform functions essential to cell survival under these conditions. C16672 Amino Acid, Peptide, or Protein Heat Shock Protein C0018850 One of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of oxygen or glucose (sugar). Heat-shock proteins help other proteins function in normal cells and may be present at high levels in cancer cells. Blocking the activity of a heat-shock protein called HSP90 is being studied in the treatment of cancer. Other heat-shock proteins including HSP70 and gp96 are being studied in vaccines to treat cancer. Heat_Shock_Protein HSP Heat Shock Protein Heat Shock Proteins heat-shock protein stress protein Heat Shock Protein A manner of living that reflects the person's values and attitudes. C16795 Social Behavior Lifestyle C0023676 Lifestyle Lifestyle Lifestyle Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders. C16809 Diagnostic Procedure Magnetic Resonance Imaging Magnetic Resonance Imaging C0024485 CDISC CTRP FDA GDC PCDC A procedure in which radio waves and a powerful magnet linked to a computer are used to create detailed pictures of areas inside the body. These pictures can show the difference between normal and diseased tissue. NMRI makes better images of organs and soft tissue than other scanning techniques, such as computed tomography (CT) or x-ray. NMRI is especially useful for imaging the brain, the spine, the soft tissue of joints, and the inside of bones. Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide amazingly clear and detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders. Magnetic_Resonance_Imaging MRI MR Imaging MRI MRI Scan Magnetic Resonance Imaging Magnetic Resonance Imaging Scan Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance NMR Imaging NMRI Nuclear Magnetic Resonance Imaging magnetic resonance imaging nuclear magnetic resonance imaging Magnetic Resonance Imaging The measurement of the magnetic fields produced by electrical activity in the brain, usually conducted externally, using extremely sensitive devices. The measurement of electric fields in the brain provides information about the localization of brain activity which is complementary to that provided by electroencephalography. C16811 Diagnostic Procedure Magnetoencephalography Magnetoencephalography C0024489 CTRP Magnetoencephalography MEG Magnetoencephalography Magnetoencephalography Proteins associated with the microtubule assembly infrastructure. These proteins include specialized motor proteins (dynein and kinesin) and smaller tubulin-crosslinking proteins (tau proteins). The proteins are required for both microtubule assembly and stabilization. C16861 Amino Acid, Peptide, or Protein Microtubule Associated Protein C0026045 Microtubule_Associated_Protein MAP MAPs Microtubule Associated Protein Microtubule-Associated Protein Microtubule-Associated Proteins Microtubule Associated Protein A representation of something, often idealized or modified to make it conceptually easier to understand. C16866 Intellectual Product Model C3161035 CDISC-GLOSS A formal structure for representing and analyzing a process such as a clinical trial or the information pertaining to a restricted context (e.g., clinical trial data). [CDISC] Model_System Model Model System Modeling System Models model Model A method of examining structures within the body by scanning them with X rays and using a computer to construct a series of cross-sectional scans along a single axis. C17204 Diagnostic Procedure Computed Tomography Computed Tomography C0040405 CDISC CTRP FDA GDC PCDC A series of detailed pictures of areas inside the body; the pictures are created by a computer linked to an x-ray machine. An imaging technique for examining structures within the body by scanning them with X rays and using a computer to construct a series of cross-sectional scans along a single axis. Computed_Tomography CT Scan CAT CAT Scan CAT scan CT CT SCAN CT Scan CT scan Computed Tomography Computerized Axial Tomography Computerized Tomography computed tomography computerized axial tomography computerized tomography tomography Computed Tomography A planned pathway assigned to the subject as they progress through the study, usually referred to by a name that reflects one or more treatments, exposures, and/or controls included in the path. C174447 Research Activity Study Arm C1522541 CDISC A planned pathway assigned to the subject as they progress through the study, usually referred to by a name that reflects one or more treatments, exposures, and/or controls included in the path. Protocol_Treatment_Arm Arm Study Arm Study Arm C17456 Intellectual Product Experimental Model C0086272 Experimental_Model Experimental Model Experimental Models, Other Experimental Model Small proteins that function as hormonal signals, synthesized and secreted by one tissue or organ with physiological effects on other tissues or organs. C1746 Amino Acid, Peptide, or Protein Hormone Peptide Hormone C0597192 Peptide_Hormone CHEBI:25905 Peptide Hormone Peptide Hormone A protein which binds to enhancers having a conserved CCAAT sequence. CCAAT enhancer binding proteins are a subclass of bZIP transcription factors that bind the CCAAT DNA sequence as homo- or heterodimers with other family members, C/EBP-alpha, beta, gamma, delta, epsilon. They include both transcriptional activators and repressors, and some are involved in myelopoiesis. C17486 Amino Acid, Peptide, or Protein Biologically Active Substance CCAAT Enhancer Binding Protein C0108685 CCAAT_Enhancer_Binding_Protein C/EBP CCAAT Enhancer Binding Protein CCAAT Enhancer Binding Protein A stage in the sequence of activities in a clinical study. C176261 Temporal Concept Study Phase CDISC-GLOSS A stage in the sequence of activities in a clinical study (e.g., Screening, Randomization, Treatment, Follow-up). See also arm, visit, phase (of clinical development), epoch. Study Phase phase (within a study) Study Phase The determination of the ratio of phosphorylated Tau protein compared to amyloid beta 1-42 present in a sample. The measurement may be expressed as a ratio or percentage. C176312 Laboratory Procedure Phosphorylated Tau Protein to Amyloid Beta1-42 Ratio Measurement CDISC A relative measurement (ratio) of the phosphorylated Tau protein to amyloid beta 1-42 in a biological specimen. PTAUAB42 Phosphorylated Tau Prot/Amyloid Beta1-42 Phosphorylated Tau Protein to Amyloid Beta1-42 Ratio Measurement Phosphorylated Tau Protein/Amyloid Beta 1-42 Phosphorylated Tau Protein to Amyloid Beta1-42 Ratio Measurement An intracellular or extracellular function, activity, or process principally involving intracellular or extracellular components. C17710 Phenomenon or Process Subcellular Process C0230625 Subcellular_Process Cell Process Subcellular Process Subcellular Process A family of structurally related proteins that are involved in both protein folding and cellular stress responses. The members of this family are approximately 70 kDa. C17765 Amino Acid, Peptide, or Protein Heat Shock Protein 70 Heat Shock Protein 70 C0243043 CTRP Heat_Shock_Protein-70 70-kD Heat Shock Protein 70-kD Heat-Shock Protein 70-kDa Heat Shock Protein HSP 70 HSP-70 HSP70 HSPA Heat Shock Protein 70 Heat Shock Protein Family A Heat Shock Protein 70 The principle of functional MRI imaging is to take a series of images of an organ in quick succession and to statistically analyze the images for differences among them. Most commonly used in studies of brain function. C17958 Diagnostic Procedure Functional Magnetic Resonance Imaging Functional Magnetic Resonance Imaging C0376335 CDISC CTRP A noninvasive tool used to observe functioning in the brain or other organs by detecting changes in chemical composition, blood flow, or both. A type of MRI that takes a series of images of an organ in quick succession and statistically analyzes the differences between the images. Functional_Magnetic_Resonance_Imaging FUNCTIONAL MRI Functional MRI Functional Magnetic Resonance Imaging fMRI functional magnetic resonance imaging Functional Magnetic Resonance Imaging Protein synthesis is the group of processes that are involved in generation of mature protein molecules. Although protein synthesis may involve translation alone in many cases, in others, it involves also protein folding, integration of prosthetic groups, glycosylation, methylation, phosphorylation, lipidation and any other process that may be involved in maturation of the polypeptide to the biologically active form. C18103 Molecular Function Protein Synthesis C0597295 Protein_Synthesis Protein Synthesis Protein Synthesis Caspases are a family of intracellular cysteine proteinases involved in inflammation and apoptosis. These enzymes appear to be involved in the initial signaling events, as well as the downstream proteolytic cleavages, that result in apoptotic cell death. They are specific for aspartic acid at the P1 position and are divided into two classes based on the lengths of their N-terminal pro-domains. Caspases-1, -2, -4, -5, -8, and -10 have long pro-domains; caspases-3, -6, -7, and -9 have short pro-domains. (from Science 1998. 281:1312 and Br Med Bull 1997. 53:478) C18153 Amino Acid, Peptide, or Protein Enzyme Caspase Caspase C0010656 CTRP Caspase Caspase Caspases Cell-Death Protease Cysteine-Dependent Aspartate-Directed Protease Cysteine-aspartic Protease ICE-like protease ICE-like proteases Peptidase Family C14 TNF Alpha ICE Proteinases Caspase Specific metabolic changes that characterize an organism's state of health or disease, or response to a particular therapeutic intervention, and helps make diagnosis more accurate or enable physicians to make diagnosis before symptoms appear and to track disease progression. C18520 Functional Concept Metabolic Marker C1513159 Metabolic_Marker Metabolic Marker Metabolic Marker In vitro (Latin for within the glass) refers to the technique of performing a given procedure in a controlled environment outside of a living organism. C19146 Research Activity In Vitro Model C1515654 in_vitro_Model In Vitro Model In Vitro Model In vitro (Latin for within the glass) refers to the technique of performing a given procedure in a controlled environment outside of a living organism. https://mpkb.org/home/patients/assessing_literature/in_vitro_studies In vivo (Latin for “within the living”) refers to experimentation using a whole, living organism as opposed to a partial or dead organism. C19148 Research Activity In Vivo Model C1515657 in_vivo_Model In Vivo Model In Vivo Model In vivo (Latin for “within the living”) refers to experimentation using a whole, living organism as opposed to a partial or dead organism. https://mpkb.org/home/patients/assessing_literature/in_vitro_studies A disease in a transgenic animal with pathologic mechanisms sufficiently similar to those of a human disease for the animal disease to serve as a model. C19272 Experimental Model of Disease Transgenic Model C1519606 Transgenic_Model Transgenic Model Transgenic Model The distinguishing qualities or prominent aspects of an individual person. C19332 Organism Attribute Personal Attribute C0681884 Personal_Attribute Personal Personal Attribute Subject Characteristics Personal Attribute The visualization of physiological, cellular or molecular processes in living tissue in real time as they take place in cells, for example, blood flow, oxygen consumption or glucose metabolism. (Bypass Budget) C19609 Diagnostic Procedure Functional Imaging C1517324 Functional_Imaging Functional Imaging Physiologic Imaging Functional Imaging Proteins secreted out of the cell to perform a function in the extracellular medium. C20031 Amino Acid, Peptide, or Protein Extracellular Protein C1333498 Extracellular_Protein Extracellular Protein Extracellular Protein The X-ray examination of the blood vessels or chambers of the heart. C20080 Diagnostic Procedure Angiography Angiography CL378222 CDISC CTRP A method used to create an image of blood vessels. A procedure to x-ray blood vessels. The blood vessels can be seen because of an injection of a dye that shows up in the x-ray. Angiography ANGIOGRAPHY Angiography angiography Angiography Collection of proteins that are evolutionarily related. This is reflected in the structural and functional similarities as well as in the extent of sequence conservation or residue identity. (from SCOP) C20130 Classification Protein Family C1335532 Protein_Family Protein Family Protein Family Any substance that inhibits protein farnesyltransferase, an enzyme that catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine. Protein farnesyltransferase is involved in Ras-mediated post-translational modification. Inhibition of protein farnesyltransferase may inhibit the oncogenic activity of Ras. C2020 Chemical Viewed Functionally Farnesyl Transferase Inhibitor C1517132 Farnesyl_Transferase_Inhibitor CHEBI:64133 FTI Farnesyl Transferase Inhibitor Farnesyl Transferase Inhibitors Farnesyltransferase Inhibitors Protein Farnesyltransferase Inhibitor Protein Farnesyltransferase Inhibitors Farnesyl Transferase Inhibitor A family of protein growth factors produced by the nervous system and peripheral target tissues. These proteins are critical for development, growth, regeneration, survival, and differentiation of neurons. C20391 Amino Acid, Peptide, or Protein Biologically Active Substance Neurotrophic Factor C0132298 Neurotrophic_Factor Neurotrophin signaling is mediated by the Trk family of receptor tyrosine kinases. (IP, N. Y. (1998), The Neurotrophins and Neuropoietic Cytokines: Two Families of Growth Factors Acting on Neural and Hematopoietic Cells. Annals of the New York Academy of Sciences, 840: 97-106. doi: 10.1111/j.1749-6632.1998.tb09553.x) Neurotrophic Factor Neurotrophin Neurotrophic Factor Growth Factors are extracellular signaling molecules (ligands) involved in control of target cell proliferation, cell survival, and cell differentiation. (NCI) C20424 Amino Acid, Peptide, or Protein Growth Factor Growth Factor C0018284 CTRP Substances made by the body that function to regulate cell division and cell survival. Some growth factors are also produced in the laboratory and used in biological therapy. Growth_Factor Growth Agents Growth Factor Growth Factors Growth Factors, Proteins Mitogen growth factor Growth Factor Any evaluation or assessment tool used to ascertain a patient's condition or diagnosis. C20993 Intellectual Product Research or Clinical Assessment Tool C1516602 NICHD Clinical_Assessment_Tool Clinical Assessment Tool Clinical Assessment Tool Clinical or Research Assessment Tool Research or Clinical Assessment Tool Research or Clinical Assessment Tool Changes in the regulation of the expression of gene activity without alteration of genetic structure. C21051 Genetic Function Epigenetic Process Epigenetic Process C1516924 CTRP Epigenetic_Process Epigenetic Change Epigenetic Mechanism Epigenetic Process Epigenetics Epigenetic Process The process of allaying nervous excitement or the state of being calmed. (Taber's) C21097 Therapeutic or Preventive Procedure Sedation C0344106 Patient Code (Appendix B) FDA Patient required sedation or additional sedation. Sedation IMDRF:F17 Sedation Sedation Small, soluble Synuclein Family proteins are a group of highly conserved post-transcriptionally modified Alpha, Beta, and Gamma proteins expressed primarily in neural tissue and often localized near synaptic vesicles. Synucleins may inhibit PLD2 and regulate vesicular transport. In the N-terminal portion, synucleins have a conserved repeated 11-residue amphipathic alpha-helical motif similar to the lipid-binding A2 domain of apolipoproteins. Synucleins also contain several repeated variations of a highly conserved KTKEGV domain, also present in rho family proteins. In brain, synucleins may be phosphorylated by Ca2+ calmodulin protein kinase II. Synucleins are overexpressed in breast carcinomas and mutations are associated with neurodegenerative illnesses. C21217 Amino Acid, Peptide, or Protein Synuclein Family C1336547 Synuclein_Family Synuclein Family Synuclein Family Any of the serum proteins that interact with antigen antibody complex to produce cytolytic, chemotaxic, anaphylactic, and other effects. (from CSP2000) C21523 Amino Acid, Peptide, or Protein Complement Component Protein C0312743 One of a group of about 20 proteins that is found in the blood and is important in fighting infections and other diseases. Complement_Component_Protein Complement Component Protein complement protein Complement Component Protein Systematic, objective appraisal of the significance, effectiveness, and impact of activities or condition according to specified objectives and criteria. C25214 Activity Evaluation Evaluation C0220825 CTRP NICHD Evaluation Evaluation Procedure Evaluate Evaluated Evaluation Evaluation Procedure Evaluation Anything that contributes causally to a result. C25506 Functional Concept Factor C1521761 Factor Determinant Factor Factor The selection and obtaining of small representative quantities of biological material for the purpose of analysis; also, in biomedical statistics, sampling is the selection and implementation of statistical observations in order to estimate properties of an underlying population; also, in environmental science, the collection of representative specimens analyzed to characterize site conditions. C25662 Activity Sampling C0870078 Sampling Sampling Sampling Enlargement; expansion in size; sign of inflammation C3399 Sign or Symptom Swelling C0038999 Patient Code (Appendix B) FDA Swelling Swelling Swelling A traumatic injury to the head. C34660 Finding Head Injury C0018674 Patient Code (Appendix B) FDA NICHD A traumatic injury to the head. Head_Injury Head Injury IMDRF:E1610 Head Injury Injury of Head Head Injury A radiographic procedure using the emission of x-rays to form an image of the structure penetrated by the radiation. C38101 Diagnostic Procedure Radiography X-Ray Imaging C0043299 CDISC CTRP PCDC A radiographic procedure using the emission of x-rays, a type of penetrating energy wave. Radiography Conventional X-Ray Diagnostic Radiology Medical Imaging, X-Ray Radiography Static X-Ray X-RAY X-Ray X-Ray Imaging X-ray X-Ray Imaging C38834 Functional Concept MAPK Signaling Pathway C1518102 hsa04010 The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals express at least four distinctly regulated groups of MAPKs, extracellular signal-related kinases (ERK)-1/2, Jun amino-terminal kinases (JNK1/2/3), p38 proteins (p38alpha/beta/gamma/delta) and ERK5, that are activated by specific MAPKKs: MEK1/2 for ERK1/2, MKK3/6 for the p38, MKK4/7 (JNKK1/2) for the JNKs, and MEK5 for ERK5. Each MAPKK, however, can be activated by more than one MAPKKK, increasing the complexity and diversity of MAPK signalling. Presumably each MAPKKK confers responsiveness to distinct stimuli. For example, activation of ERK1/2 by growth factors depends on the MAPKKK c-Raf, but other MAPKKKs may activate ERK1/2 in response to pro-inflammatory stimuli. MAPK_Signaling_Pathway MAPK Signaling Pathway MAPK Signaling Pathway A twenty-one question survey completed by a patient, with each answer scored on a scale of 0 to 3, designed to measure presence of depression. C40438 Intellectual Product Beck Depression Inventory C0451022 Beck_Depression_Inventory Beck Depression Inventory Beck Depression Inventory A matter or an individual that is observed, analyzed, examined, investigated, experimented upon, or/and treated in the course of a particular study. C41189 Functional Concept Study Subject Study Subject C0681850 BRIDG CDISC CTRP A physical entity which is the primary unit of operational and/or administrative interest in a study. EXAMPLE(S): A person who is registered in a study as a recipient of an investigational product or as a control. Individuals who are being screened for studies. Individuals participating in observational or other studies. A pacemaker, a fuse that can be used in medical devices, a cow, a pen of pigs, or a tissue sample from a tissue bank. OTHER NAME(S): NOTE(S): StudySubjects within a study are all of the same type. An entity registered in a study is not part of another entity registered in the same study. A physical entity which is the primary unit of operational and/or administrative interest in a study. EXAMPLE(S): A person who is registered in a study as a recipient of an investigational product or as a control. Individuals who are being screened for studies. Individuals participating in observational or other studies. A pacemaker, a fuse that can be used in medical devices, a cow, a farm, a pen of pigs, or a tissue sample from a tissue bank. NOTE(S): StudySubjects within a study are all of the same type. An entity registered in a study is not part of another entity registered in the same study. An individual who is observed, analyzed, examined, investigated, experimented upon, or/and treated in the course of a particular study. Study_Subject STUDY SUBJECT Study Participant Study Subject StudySubject Subject Study Subject A study in which the participants are assigned by chance to separate groups to evaluate treatments. The study also includes a control group, which is undergoing the same rigors of the study with placebo treatment or standard treatment. The trial can also be controlled by the addition of a test group to ensure there are no factors present to skew the results and by the inclusion of peer-review analysis by appropriate government officials. 2005 C46079 Research Activity Randomized Controlled Clinical Trial C0206035 Randomized_Controlled_Clinical_Trial Randomized Controlled Clinical Trial Randomized Controlled Clinical Trial Interference or disruption of memory processes. Memory dysfunction refers to the inability to store and retrieve information. This term encompasses a large number of problems and issues associated with intellectual functioning. 2005 C46084 Mental or Behavioral Dysfunction Memory Dysfunction C3887551 Memory_Dysfunction Memory Dysfunction Memory Dysfunction A class of fatty acids derived from the oxidation of one of three 20-carbon fatty acids: eicosapentaenoic acid (EPA), arachidonic acid (AA), or dihomo-gamma-linolenic acid (DGLA). Eicosanoids act locally as autocrine or paracrine hormones to modulate a wide variety of biological processes. C463 Biologically Active Substance Organic Chemical Eicosanoid Eicosanoid C0013725 CTRP Eicosanoid CHEBI:23899 Eicosanoid Eicosanoids Eicosanoid A study in which a group or cohort of individuals is followed for a certain length of time or until a specific outcome is reached. Studies of this type incorporate the strengths of both cohort and case-control studies but eliminates a portion of the methodologic challenges inherent in both types of studies. C48202 Research Activity Nested Case-control Study C0027775 Nested_Case-control_Study Nested Case-control Study Nested Case-control Study A systematic examination or assessment. C48261 Diagnostic Procedure Screening Screening C1710032 CTRP Screening_Generic Screening Screening Generic Screening A part, fraction, share, or number considered in relation to the whole amount or number. C49159 Quantitative Concept Proportion C1709707 Proportion Proportion Proportion A clinical research protocol generally referred to as a pilot or feasibility trial that aims to prove the concept of the new intervention in question. C49686 Research Activity Phase IIa Trial C1706446 CDISC CDISC-GLOSS A clinical research protocol generally referred to as a pilot or feasibility trial that aims to prove the concept of the new intervention in question. (NCI) Controlled clinical studies that occur after the completion of Phase 1 studies and the first set of exposure-response studies in patients, and before beginning Phase 2b (i.e., patient dose-ranging trial) and Phase 3 clinical efficacy-safety studies. [FDA draft Guidance for industry end of Phase 2a meetings, 9/08]. Phase_IIA_Trial 2A PHASE IIA TRIAL Phase IIa Trial Trial Phase 2A Trial Phase IIA phase 2a Phase IIa Trial A clinical research protocol generally referred to as a well-controlled and pivotal trial that aims to prove the mechanism of action of the new intervention in question. A pivotal study will generally be well-controlled, randomized, of adequate size, and whenever possible, double-blind. C49688 Research Activity Phase IIb Trial C1706096 CDISC A clinical research protocol generally referred to as a well-controlled and pivotal trial that aims to prove the mechanism of action of the new intervention in question. A pivotal study will generally be well-controlled, randomized, of adequate size, and whenever possible, double-blind. (NCI) Phase_IIB_Trial 2B PHASE IIB TRIAL Phase IIb Trial Trial Phase 2B Trial Phase IIB Phase IIb Trial The death rate, or proportion of a given population that dies, during a specified time period, statistically modified to eliminate the effect of the various age distributions. C53360 Quantitative Concept Age-Adjusted Mortality Rate C1706748 Age-Adjusted_Mortality_Rate Age-Adjusted Mortality Rate Age-Adjusted Mortality Rate A clinical trial that uses an investigational agent that is available only in very limited quantities and which has never previously given to humans or for which there is extremely limited human experience. Phase 0 clinical trials are intended to enable researchers to understand the path of the drug in the body and its efficacy. Adverse event reporting in Phase 0 trials is expedited. C54721 Research Activity Phase 0 Trial C1882358 CDISC CDISC-GLOSS First-in-human trials, in a small number of subjects, that are conducted before Phase 1 trials and are intended to assess new candidate therapeutic and imaging agents. The study agent is administered at a low dose for a limited time, and there is no therapeutic or diagnostic intent. NOTE: FDA Guidance for Industry, Investigators, and Reviewers: Exploratory IND Studies, January 2006 classifies such studies as Phase 1. NOTE: A Phase 0 study might not include any drug delivery but may be an exploration of human material from a study (e.g., tissue samples or biomarker determinations). [Improving the Quality of Cancer Clinical Trials: Workshop summary-Proceedings of the National Cancer Policy Forum Workshop, improving the Quality of Cancer Clinical Trials (Washington, DC, Oct 2007)] First-in-human trials, in a small number of subjects, that are conducted before Phase 1 trials and are intended to assess new candidate therapeutic and imaging agents. The study agent is administered at a low dose for a limited time, and there is no therapeutic or diagnostic intent. NOTE: FDA Guidance for Industry, Investigators, and Reviewers: Exploratory IND Studies, January 2006 classifies such studies as Phase 1. NOTE: A Phase 0 study might not include any drug delivery but may be an exploration of human material from a study (e.g., tissue samples or biomarker determinations). [Improving the Quality of Cancer Clinical Trials: Workshop summary-Proceedings of the National Cancer Policy Forum Workshop, improving the Quality of Cancer Clinical Trials (Washington, DC, Oct 2007)] (CDISC glossary) Phase_0_Trial 0 PHASE 0 TRIAL Phase 0 Phase 0 Trial Pre-Clinical Trial Pre-clinical Trial Trial Phase 0 phase 0 Phase 0 Trial Measures basic skills in reading, arithmetic, and spelling. It is a screening test that can be administered to determine if a more comprehensive achievement test is needed. C62716 Intellectual Product Wide Range Achievement Test, 3rd Edition C1883557 Wide_Range_Achievement_Test_3rd_Edition Wilkinson, S. S., Author (1993); Published by Wide Range, Inc WRAT-3 Wide Range Achievement Test, 3rd Edition Wide Range Achievement Test, Revision 3 Wide Range Achievement Test-3 Wide Range Achievement Test, 3rd Edition Part of a risk that is identified as due to exposure to a defined factor. C67360 Quantitative Concept Attributable Risk C0814766 Proportion of a disease in exposed individuals that can be attributed to an exposure. In the context of genetic studies, the exposure is the frequency of a specific genetic variant. Attributable_Risk Attributable Risk attributable risk Attributable Risk C70820 Research Activity Clinical Study by Phase C2347801 Clinical_Study_by_Phase Clinical Study by Phase Clinical Study by Phase A clinical study that is designed using a procedure in which one or more parties to the study [subject(s), investigator(s), monitor, or/and data analyst(s)] are kept unaware of the treatment assignment(s). C70840 Research Activity Blinded Clinical Study C2347038 CDISC-GLOSS GDC A study in which the subject, the investigator, or anyone assessing the outcome is unaware of the treatment assignment(s). NOTE: Blinding is used to reduce the potential for bias. [Modified ICH E6 Glossary] See also blinding/masking, double-blind study, single-blind study, triple-blind study; contrast with open-label or unblinded study. A type of study in which the patients (single-blinded) or the patients and their doctors (double-blinded) do not know which drug or treatment is being given. The opposite of a blinded study is an open label study. Blinded_Clinical_Study Blinded Study, Treatment Unknown Blind Clinical Study Blinded Clinical Study Blinded Clinical Trial Masked Clinical Study blinded study Blinded Clinical Study An animal that is amenable to experimentation and whose physiological or pathologic mechanisms are sufficiently similar to those of a human for the animal to serve as a model. C71164 Research Activity Animal Model C0599779 Animal_Model_Generic Animal Model Animal Model, Generic Research Model, Animal Animal Model A quantitative measurement of the distance that red blood cells travel in one hour in a sample of unclotted blood. C74611 Laboratory Procedure Erythrocyte Sedimentation Rate Measurement Erythrocyte Sedimentation Rate Measurement C1176468 ACC/AHA CDISC CPTAC CTRP NICHD PCDC A quantitative measurement of the distance that red blood cells settle in one hour in a sample of unclotted blood. Used in the evaluation of systemic inflammation. A quantitative measurement of the distance that red blood cells travel in 1 hour in a sample of unclotted blood. The distance (e.g. millimeters) that red blood cells settle in unclotted blood over a specified unit of time (e.g. one hour). The distance red blood cells travel in one hour in a sample of blood as they settle to the bottom of a test tube. The sedimentation rate is increased in inflammation, infection, cancer, rheumatic diseases, and diseases of the blood and bone marrow. Erythrocyte_Sedimentation_Rate_Measurement Erythrocyte Sedimentation Rate Biernacki Reaction ESR Erythrocyte Sedimentation Rate Erythrocyte Sedimentation Rate Measurement Erythrocyte sedimentation rate (ESR) Sed Rate erythrocyte sedimentation rate sedimentation rate Erythrocyte Sedimentation Rate Measurement A standardized and structured interview originally developed by Marshal Folstein, Susan Folstein and Paul McHugh (Journal of Psychiatric Research, 1975), which is used to evaluate an individual's cognitive function. C74982 Intellectual Product Mini-Mental Status Exam C0451306 CDISC Mini-Mental State Examination (MMSE) (MMSE Copyright 1975, 1998, 2001 by MiniMental, LLC All rights reserved. Published 2001 by Psychological Assessment Resources, Inc. May not be reproduced in whole or in part in any form or by any means without written permission of Psychological Assessment Resources, Inc.). Mini-Mental_Status_Exam Folstein Mini-Mental Status Exam MMS1 MMSE Mini-Mental State Examination Questionnaire Mini-Mental Status Exam Mini-Mental Status Exam C76786 Pharmacologic Substance Tramiprosate C0062961 3687-18-1 5K8EAX0G53 FDA C3H9NO3S Tramiprosate Alzhemed Homotaurine TRAMIPROSATE Tramiprosate Tramiprosate C78757 Pharmacologic Substance Latrepirdine C0058188 3613-73-8 Alzheimer's disease OD9237K1Z6 FDA C21H25N3 Dimebolin 2,3,4,5-Tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)ethyl)-1H-pyrido(4,3-b)indole Dimebolin Dimebon LATREPIRDINE Latrepirdine Latrepirdine A humanized monoclonal antibody (IgG1) raised against amyloid beta peptides with Alzheimer disease treatment application. Bapineuzumab recognizes and binds the N-terminal amino acids 1-5 of the amyloid beta peptide, and may be used in a passive immunotherapy treatment. C79569 Amino Acid, Peptide, or Protein Pharmacologic Substance Bapineuzumab C2698328 648895-38-9 Alzheimer's disease NC11WKO35D FDA Bapineuzumab AAB-001 Anti-human beta-amyloid Monoclonal Antibody 3D-6 BAPINEUZUMAB Bapineuzumab Humanized 3D-6 Monoclonal Antibody Bapineuzumab Systems designed to elucidate facts about complex biological phenomena, usually in a less complex or theoretical test environment. C80519 Intellectual Product Biological Model C0026339 Biological_Model Biological Model Biological Models Model Model System Biological Model C81115 Pharmacologic Substance Semagacestat C1614973 425386-60-3 3YN0602W4W FDA C19H27N3O4 Semagacestat LY-450139 SEMAGACESTAT Semagacestat Semagacestat The determination of the amount of the 1-42 amino acid beta amyloid protein isoform present in a sample. C84809 Laboratory Procedure Beta Amyloid 42 Measurement C2827504 CDISC A measurement of amyloid beta protein which is composed of peptides 1 to 42 in a biological specimen. AMYLB42 Amyloid Beta 1-42 Amyloid Beta 1-42 Measurement Amyloid Beta 42 Amyloid Beta 42 Protein Beta Amyloid 1-42 Measurement Beta Amyloid 42 Measurement Beta Amyloid 42 Measurement The determination of the amount of Tau protein present in a sample. C84810 Laboratory Procedure Tau Protein Measurement C2827505 CDISC A measurement of the total Tau protein in a biological specimen. TPROT Tau Protein Tau Protein Measurement Total Tau Protein Tau Protein Measurement The determination of the amount of phosphorylated Tau protein present in a sample. C84812 Laboratory Procedure Phosphorylated Tau Protein Measurement C2827507 CDISC A measurement of the phosphorylated Tau protein in a biological specimen. Phosphorylated Tau Protein Phosphorylated Tau Protein Measurement TPROTP Phosphorylated Tau Protein Measurement Criteria for the diagnosis of Alzheimer's disease (AD), proposed in 1984 by the National Institute of Neurological and Communicative Disorders (NINCDS) and the Stroke-Alzheimer's Disease and Related Disorders Association (ADRDA, now the Alzheimer's Association). The criteria state that existing cognitive impairment may be considered possible or probable AD by neuropsychological testing but definitive diagnosis requires histopathologic confirmation. They specify eight cognitive domains that may be impaired in AD: memory, language, perceptual skills, attention, constructive abilities, orientation, problem solving, and functional abilities. C86983 Idea or Concept NINCDS-ADRDA Criteria for Alzheimer's Disease C2828081 NINCDS-ADRDA Criteria for Alzheimer's Disease National Institute of Neurological and Communicative Disorders and Stroke and Alzheimer's Disease and Related Disorders Association Criteria for Alzheimer's Disease NINCDS-ADRDA Criteria for Alzheimer's Disease A set of mental processes that controls and manages the cognitive functions. C88419 Mental Process Executive Function C0935584 Executive Function Executive Function A question pertaining to a clinical or research assessment. C91102 Intellectual Product Clinical or Research Assessment Question C2984039 Clinical or Research Assessment Question Clinical or Research Assessment Question An instrument consisting of a predetermined set of questions for a clinical or research assessment. C91105 Intellectual Product Clinical or Research Assessment Questionnaire C2984042 Clinical or Research Assessment Questionnaire Clinical or Research Assessment Questionnaire C93150 Quantitative Concept Hazard Ratio C2985465 A measure of how often a particular event happens in one group compared to how often it happens in another group, over time. In cancer research, hazard ratios are often used in clinical trials to measure survival at any point in time in a group of patients who have been given a specific treatment compared to a control group given another treatment or a placebo. A hazard ratio of one means that there is no difference in survival between the two groups. A hazard ratio of greater than one or less than one means that survival was better in one of the groups. Hazard Ratio hazard ratio Hazard Ratio C93228 Research Activity Retrospective Cohort Study C2985505 A research study in which the medical records of groups of individuals who are alike in many ways but differ by a certain characteristic (for example, female nurses who smoke and those who do not smoke) are compared for a particular outcome (such as lung cancer). Retrospective Cohort Study historic cohort study retrospective cohort study Retrospective Cohort Study A protein complex that plays a role in the intramembrane cleavage of integral proteins such as Notch receptors and amyloid beta A4 protein. C95114 Amino Acid, Peptide, or Protein Enzyme Gamma Secretase C0379528 The components required for the enzymatic activity of gamma secretase are a homodimer of presenilin (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. The proteolytic activity appears to be mediated by presenilin, while the other proteins are required for both stabilization of the active form of presenilin and localization of the complex. Gamma Secretase Gamma-Secretase Gamma Secretase A physical interaction between exactly two molecules or subunits to create a lasting compound. C97201 Molecular Function Dimerization C0376525 Dimerization Dimerize Dimerization Any antidiabetic agent with the glitazone (thiazolidinedione) base structure with antihyperglycemic activity. Glitazone antidiabetic agents selectively bind to and stimulate the nuclear receptor peroxisome proliferator-activated receptor (PPAR) gamma. This results in the selective transcription of a number of insulin-sensitive genes involved in glucose metabolism. This eventually enhances insulin sensitivity, reduces insulin resistance and decreases hepatic gluconeogenesis. PPARs function as transcription factors that regulate expressions of genes involved in cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), as well as tumorigenesis; PPARgamma is expressed at high levels in adipose tissue. C98241 Chemical Viewed Functionally Thiazolidinedione Antidiabetic Agent C3273907 GDC Thiazolidinedione Thiazolidinedione Thiazolidinedione Antidiabetic Agent Thiazolidinedione Antidiabetic Agent The primary measurement(s) or observation(s) used to measure the effect of experimental variables in a study, or for observational studies, to describe patterns of diseases or traits or associations with exposures, risk factors or treatment. These are the outcome measures used to assess the primary objective(s). C98772 Intellectual Product Primary Outcome Measure C3274433 CDISC The outcome measure(s) of greatest importance specified in the protocol, usually the one(s) used in the power calculation, to evaluate the primary endpoint(s) associated with the primary study objective(s). (After Clinicaltrials.gov) OUTMSPRI PRIMARY OUTCOME MEASURE Primary Outcome Measure Primary Outcome Measure Other key measures that will be used to evaluate the intervention(s) or, for observational studies, that are a focus of the study. These are the outcome measures used to assess the secondary objective(s). C98781 Intellectual Product Secondary Outcome Measure C3274440 CDISC The outcome measure(s) that is part of a pre-specified analysis plan used to evaluate the secondary endpoint(s) associated with secondary study objective(s) and/or used to evaluate any measure(s) ancillary to the primary or secondary endpoint(s). (After Clinicaltrials.gov). OUTMSSEC SECONDARY OUTCOME MEASURE Secondary Outcome Measure Secondary Outcome Measure a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event. Melanie Courtot and YH: More work is needed on how to restrict the scope of a term to be an 'adverse event', notably regarding temporal association. When is an appropirate time interval between a medical intervention and an adverse event observed? One week, one month, one year, or a lifetime? For some well-studied medical interventions (e.g., administration of many vaccines or drugs), we probably have a general idea. For many new interventions, we don't know much. In OAE, this issue is associated with defining the 'adverse event incubation time'. YH: An adverse event is a process that has specified output of some adverse medical outcome (e.g., symptom, sign or accident) after a medical intervention (or process) (e.g., administration of drug or vaccine). The medical intervention can be an administration of a drug, a vaccine (i.e., vaccination), or a special nutritional product (for example, dietary supplement, infant formula, medical food), surgery, or usage of a medical device. YH: An adverse event is possibly induced by the medical intervention. It can be caused by the medical intervention, or may not be caused by the medical intervention. One ultimate goal (or the goal in clinics) of study adverse events is to assess if the adverse event outcome is due to the medical intervention. YH: In development of OAE, we initially use vaccine adverse event as our use case. A vaccine adverse event is associated with a vaccination (i.e. a medical intervention), regardless of whether it is considered vaccine-related, and includes any side effect, injury, toxicity, or sensitivity reaction or significant failure of immunization (i.e., a pharmacologic action). Ref: Baylor NW and Midthum K. Regulation and testing of vaccines. In: Vaccines (Editors: Plotkin S, Orenstein W, and Offit P). 2008. p1623. YH: The current term 'adverse event' is different from the term definition shown in our paper: He Y, Xiang Z, Sarntivijai S, Toldo L, Ceusters W. OAE: a realism-based biomedical ontology for the representation of adverse events. Adverse Event Representation Workshop, International Conference on Biomedical Ontologies (ICBO), University at Buffalo, NY, July 26-30, 2011. Full lenghth conference proceeding paper. We made the name changing in order to make OAE cover the broader sense of the 'adverse event' which does not assume definite causal effect between an adverse event and a medical intervention. In current definition, the adverse event emphasizes the time association and assumes a likelihood of such a causal association. This term 'adverse event' is stil under the OGMS:pathological bodily process. The 'adverse event' defined in the above paper has now been changed to a new term: 'causal adverse event'. See more information in the new publication: Yongqun He Y, Sirarat Sarntivijai, Yu Lin, Zuoshuang Xiang, Abra Guo, Shelley Zhang, Desikan Jagannathan, Luca Toldo, Cui Tao and Barry Smith. OAE: The Ontology of Adverse Events. Journal of Biomedical Semantics. 2014, 5:29 doi:10.1186/2041-1480-5-29. PMID: 25093068.PMCID: PMC4120740. YH: The main scope of OAE includes: (1) represent terms and relations in the area of adverse events, (2) assess possible associations between an adverse event and a medical intervention, particularly, identify any causal effect of a medical intervention to an adverse event; and (2) understand the mechanism (including molecular mechanisms) of causal adverse events. YH: There has been discussion regarding whether the term 'side effect' is an alternative term for 'adverse event'. In AERO, the term 'AERO:adverse event' represents a subset of those adverse events for which causality has been established. In OAE, an adverse event for which causality has been established is called 'causal adverse event'. Yongqun He AE adverse reaction WEB: http://en.wikipedia.org/wiki/Adverse_event WEB: http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm WEB: http://www.ncbi.nlm.nih.gov/pubmed/25093068 The OAE official website is: http://www.oae-ontology.org/. adverse event medical intervention is a planned process that has the goal of diagnosing, preventing or relieving illness or injury. The act of intervening, interfering or interceding with the intent of modifying the outcome. In medicine, an intervention is usually undertaken to help treat or cure a condition. For example, "Acupuncture as a therapeutic intervention is widely practiced in the United States," Reference: http://www.medterms.com/script/main/art.asp?articlekey=34214 . Some interventions can be used for diagnosis. YH WEB: http://wiki.answers.com/Q/What_is_medical_intervention medical intervention an adverse effect that occurs after a drug administration: an appreciably harmful or unpleasant reaction resulting from an intervention related to the use of a medicinal product YH, SJ http://www.ncbi.nlm.nih.gov/pubmed/11072960 10061623 adverse drug effect an adverse event that occurs in brain. YH brain disorder AE brain AE oba OBA:0000141 http://code.google.com/p/pato/issues/detail?id=2 synaptic plasticity a data transformation that has input of mulitple data and report overall trend of the data. Jie Zheng, Oliver He WEB: https://en.wikipedia.org/wiki/Statistics statistical data analysis An information content entity that represents a type of scale on which a variable is measured, including nominal, ordinal, interval, ratio. Marcy Harris level of measurement scale of measure WEB: http://en.wikipedia.org/wiki/Level_of_measurement measurement scale A data item of an observed or calculated probability of occurrence of an event, X, in a population related to exposure to a specific hazard, infection, trauma; the number of persons suffering from a disease when the exposed population is known with certainty. Yongqun He WEB: http://medical-dictionary.thefreedictionary.com/absolute+risk absolute risk A data item that refers to the number of new events that have occurred in a specific time interval divided by the population at risk at the beginning of the time interval. The result gives the likelihood of developing an event in that time interval. Yongqun He incidence WEB: http://www.uptodate.com/contents/glossary-of-common-biostatistical-and-epidemiological-terms Incidence rate A data item that refers to the number of individuals with a given disease at a given point in time divided by the population at risk at a specified point in time or over a specified period of time. Yongqun He, Jie Zheng prevalence WEB: http://health.mo.gov/training/epi/PrevalenceRates.html WEB: http://www.uptodate.com/contents/glossary-of-common-biostatistical-and-epidemiological-terms prevalence rate A data item that equals the incidence in exposed individuals divided by the incidence in unexposed individuals. The relative risk can be calculated from studies in which the proportion of patients exposed and unexposed to a risk is known, such as a cohort study. Yongqun He WEB: http://www.uptodate.com/contents/glossary-of-common-biostatistical-and-epidemiological-terms relative risk A non-parametric test of the null hypothesis that two populations are the same against an alternative hypothesis Marcy Harris Wilcoxon rank-sum test WEB: http://en.wikipedia.org/wiki/Mann%E2%80%93Whitney_U mann-whitney U test A data item which is the ratio of observed deaths in the study group to expected deaths in the general population. Person: Jie Zheng, Oliver He SMR http://en.wikipedia.org/wiki/Standardized_mortality_ratio standardized mortality ratio A data item that is derived from an inferential statistical data analysis. Jie Zheng, Yongqun He inferential statistic WEB: http://psc.dss.ucdavis.edu/sommerb/sommerdemo/stat_inf/intro.htm WEB: http://www.ask.com/question/what-is-numerical-data derived data from inferential statistical analysis A rate of deaths (in general, or due to a specific cause) that in a particular population, scaled to the size of that population, per unit of time. Jie Zheng https://en.wikipedia.org/wiki/Mortality_rate mortality rate planned process planned process Injecting mice with a vaccine in order to test its efficacy A process that realizes a plan which is the concretization of a plan specification. A processual entity that realizes a plan which is the concretization of a plan specification. 'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.) We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some objectives is a planned process. We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some objectives is a planned process. Bjoern Peters branch derived 6/11/9: Edited at workshop. Used to include: is initiated by an agent This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call) planned process drug role http://www.answers.com/topic/drug 1. A substance used in the diagnosis, treatment, or prevention of a disease or as a component of a medication. 2. Such a substance as recognized or defined by the U.S. Food, Drug, and Cosmetic Act. a role borne by a molecular entity and is realized in a process of absorption by an organism alters, or effects (or is assumed to effect) a function(s) which inhere in an organism Role Branch drug OBI, CDISC drug role processed material Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples Is a material entity that is created or changed during material processing. PERSON: Alan Ruttenberg processed material assay Assay the wavelength of light emitted by excited Neon atoms. Count of geese flying over a house. A planned process with the objective to produce information about some evaluant A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies. 12/3/12: BP: the reference to the 'physical examination' is included to point out that a prediction is not an assay, as that does not require physical examiniation. PlanAndPlannedProcess Branch measuring scientific observation OBI branch derived study assay any method assay material processing A cell lysis, production of a cloning vector, creating a buffer. A planned process which results in physical changes in a specified input material PERSON: Bjoern Peters PERSON: Frank Gibson PERSON: Jennifer Fostel PERSON: Melanie Courtot PERSON: Philippe Rocca Serra material transformation OBI branch derived material processing population PMID12564891. Environ Sci Technol. 2003 Jan 15;37(2):223-8. Effects of historic PCB exposures on the reproductive success of the Hudson River striped bass population. a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area 1/28/2013, BP, on the call it was raised that we may want to switch to an external ontology for all populatin terms: http://code.google.com/p/popcomm-ontology/ PERSON: Philippe Rocca-Serra adapted from Oxford English Dictionnary rem1: collection somehow always involve a selection process population a part of an occurrence of a disease process which is associated with position in the normal progression of the disease disease stage specimen creation a planned process with the objective of obtaining specimen. Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. Bjoern Peters 5/31/2012: This process is not necessarily an acquisition, as specimens may be collected from materials already in posession 6/9/09: used at workshop specimen collection statistical hypothesis test A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test. James Malone PERSON: James Malone statistical hypothesis test Student's t-test Studen't t-test is a data transformation with the objective of a statistical hypothesis test in which the test statistic has a Student's t distribution if the null hypothesis is true. It is applied when the population is assumed to be normally distributed but the sample sizes are small enough that the statistic on which inference is based is not normally distributed because it relies on an uncertain estimate of standard deviation rather than on a precisely known value. James Malone WEB: http://en.wikipedia.org/wiki/T-test Student's t-test study intervention the part of the execution of an intervention design study which is varied between two or more subjects in the study PERSON: Bjoern Peters GROUP: OBI study intervention data transformation The application of a clustering protocol to microarray data or the application of a statistical testing method on a primary data set to determine a p-value. A planned process that produces output data from input data. Elisabetta Manduchi Helen Parkinson James Malone Melanie Courtot Philippe Rocca-Serra Richard Scheuermann Ryan Brinkman Tina Hernandez-Boussard data analysis data processing Branch editors data transformation chi square test The chi-square test is a data transformation with the objective of statistical hypothesis testing, in which the sampling distribution of the test statistic is a chi-square distribution when the null hypothesis is true, or any in which this is asymptotically true, meaning that the sampling distribution (if the null hypothesis is true) can be made to approximate a chi-square distribution as closely as desired by making the sample size large enough. PERSON: James Malone PERSON: Tina Boussard chi square test study design a matched pairs study design describes criteria by which subjects are identified as pairs which then undergo the same protocols, and the data generated is analyzed by comparing the differences between the paired subjects, which constitute the results of the executed study design. A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution. Editor note: there is at least an implicit restriction on the kind of data transformations that can be done based on the measured data available. PERSON: Chris Stoeckert experimental design rediscussed at length (MC/JF/BP). 12/9/08). The definition was clarified to differentiate it from protocol. true study design eligibility criterion PMID: 17579629 -Eligibility criteria included: untreated ED-SCLC; age >/=70 and performance status 0-2, or age <70 and PS 3. an eligibility criterion (rule) is_a selection criterion which defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process. Person: Philippe Rocca-Serra eligibility rule Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group eligibility criterion inclusion criterion PMID: 23979341-The major inclusion criterion was patients in whom severe cerebral embolism was diagnosed at age 75 or younger (more than 9 in the NIHSS score on day 7 after the onset of stroke) . an inclusion criterion (rule) is_a *eligibility criterion* which defines and states a condition which, if met, makes an entity suitable for a given task or participation in a given process. For instance, in a study protocol, inclusion criteria indicate the conditions that prospective subjects MUST meet to be eligible for participation in a study. Person: Philippe Rocca-Serra inclusion condition inclusion rule Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group inclusion criterion exclusion rule PMID: 17600285-Exclusion criteria included the use of any topical ophthalmic or topical oral medication and/or history of ocular or oral surgery within the past six months. an exclusion criterion (rule) is_a *eligibility criterion* which defines and states a condition which, if met, makes an entity unsuitable for a given task or participation in a given process. For instance, in a study protocol, exclusion criteria indicate the conditions that prospective subjects SHOULD NOT meet to be eligible for participation in a study Person: Philippe Rocca-Serra Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group exclusion criterion A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. Oliver He WEB: http://www.ncbi.nlm.nih.gov/books/NBK21640/ gene a gene that encodes for a RNA Oliver He RNA gene A gene of an organism of Homo sapiens Yue Liu, Bin Zhao, Oliver He 9606 gene of Homo sapiens A gene of Homo sapiens that has a protein-coding gene disposition Bin Zhao, Oliver He 9606 protein-coding gene of Homo sapiens A gene of Homo sapiens that has a pseudo gene disposition Bin Zhao, Oliver He 9606 pseudo gene of Homo sapiens A gene of Homo sapiens that has a RNA gene disposition Bin Zhao, Oliver He 9606 RNA gene of Homo sapiens A gene of Homo sapiens that has a unknown gene disposition Bin Zhao, Oliver He 9606 gene of Homo sapiens with unknown gene disposition Bin Zhao, Yue Liu, Oliver He A2MD CPAMD5 FWP007 S863-7 WEB: http://www.ncbi.nlm.nih.gov/gene A2M alpha-2-macroglobulin 2 12p13.31 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0001869 (EC: IDA, PMID: 12538697); GO_0002020 (EC: IPI, PMID: 18485748); GO_0002576 (EC: TAS); GO_0004867 (EC: IDA, PMID: 12538697); GO_0005515 (EC: IPI, PMID: 14687906); GO_0005576 (EC: NAS, PMID: 14718574); GO_0005576 (EC: TAS); GO_0005829 (EC: TAS); GO_0007264 (EC: TAS); GO_0007596 (EC: TAS); GO_0007597 (EC: TAS); GO_0010951 (EC: IDA, PMID: 12538697); GO_0019838 (EC: IDA, PMID: 9398211); GO_0019899 (EC: IPI, PMID: 11435418); GO_0019959 (EC: IPI, PMID: 10880251); GO_0019966 (EC: IDA, PMID: 9714181); GO_0022617 (EC: TAS); GO_0030168 (EC: TAS); GO_0030198 (EC: TAS); GO_0031093 (EC: TAS); GO_0043120 (EC: IDA, PMID: 9714181); GO_0048863 (EC: IEA); GO_0051056 (EC: TAS); GO_0070062 (EC: IDA); GO_0072562 (EC: IDA) PMID: 59727; 80233; 89758; 1281457; 1370808; 1374237; 1692292; 1697852; 1702714; 1707161; 1724156; 2408344; 2430963; 2459995; 2460294; 2466831; 2467766; 2476070; 2581245; 3289986; 6153632; 6165619; 6167263; 6172288; 6191979; 6195065; 6203908; 6698368; 7519849; 7524416; 7533162; 7533769; 7680268; 7690356; 8583572; 8662763; 9166830; 9344465; 9398211; 9428387; 9714181; 9724081; 9831625; 9865955; 10373500; 10652313; 10681572; 10714547; 10731476; 10880251; 11023837; 11036822; 11058789; 11099722; 11100124; 11121179; 11162584; 11166925; 11231028; 11281447; 11290389; 11435418; 11436125; 11455130; 11484172; 11496365; 11498265; 11811950; 11823454; 11901360; 11910179; 11916201; 11987698; 12015318; 12042276; 12059070; 12062545; 12123860; 12175343; 12194978; 12221172; 12394648; 12477932; 12538697; 12631277; 12754519; 12755614; 12755687; 12782337; 12782964; 12966032; 14506912; 14637088; 14675603; 14678766; 14687906; 14715656; 14718574; 14759632; 14760718; 15023809; 15226301; 15231748; 15468911; 15489334; 15511627; 15611997; 15793779; 15862967; 15908432; 15910735; 15931081; 15950906; 16040006; 16169070; 16232083; 16289162; 16297527; 16335952; 16384981; 16402284; 16407218; 16456795; 16641085; 16650578; 16784755; 16910174; 17071617; 17110338; 17288987; 17403113; 17453620; 17608619; 17967834; 18029348; 18075673; 18077315; 18171086; 18191876; 18382889; 18485748; 18499670; 18579803; 18624398; 18706476; 19074141; 19105203; 19472074; 19639019; 19913121; 20048078; 20085233; 20156641; 20207732; 20301340; 20381197; 20401725; 20493925; 20575108; 20587546; 20628086; 20637261; 20800603; 20861575; 21163940; 21216953; 21541797; 21642630; 21900206; 21971609; 21988832; 22268729; 22541546; 22576683; 22971340; 23064953; 23086799; 23089609; 23186781; 23353684; 23379699; 23397525; 23535567; 23602568; 23643808; 23721263; 23786280; 23846698 alpha-2-macroglobulin Ensembl:ENSG00000175899 HGNC:7 HPRD:00072 MIM:103950 Vega:OTTHUMG00000150267 A2M Bin Zhao, Yue Liu, Oliver He ABC-1 ABC1 CERP HDLDT1 TGD WEB: http://www.ncbi.nlm.nih.gov/gene ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 19 9q31.1 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0002790 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12084722); GO_0005524 (EC: IDA, PMID: 11700048); GO_0005543 (EC: IC, PMID: 16702602); GO_0005548 (EC: IDA, PMID: 16702602); GO_0005794 (EC: IEA); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 10525055); GO_0006497 (EC: IEA); GO_0006911 (EC: IEA); GO_0007040 (EC: IDA, PMID: 15163665); GO_0007186 (EC: IMP, PMID: 16443932); GO_0007584 (EC: IEA); GO_0008203 (EC: IDA, PMID: 14747463); GO_0008509 (EC: ISS); GO_0009986 (EC: IEA); GO_0010745 (EC: TAS, PMID: 18490524); GO_0010875 (EC: IEA); GO_0010887 (EC: TAS, PMID: 18490524); GO_0015485 (EC: IC, PMID: 12084722); GO_0016197 (EC: IDA, PMID: 14747463); GO_0016887 (EC: IEA); GO_0017127 (EC: IDA, PMID: 12084722); GO_0019905 (EC: IPI, PMID: 15469992); GO_0030139 (EC: IDA, PMID: 14747463); GO_0030819 (EC: IMP, PMID: 14701824); GO_0031267 (EC: IPI, PMID: 16443932); GO_0032367 (EC: IMP, PMID: 10431236); GO_0032489 (EC: IMP, PMID: 16443932); GO_0033344 (EC: IDA, PMID: 10431236); GO_0033344 (EC: IMP, PMID: 16443932); GO_0033700 (EC: IDA, PMID: 10431236); GO_0033700 (EC: IMP, PMID: 16702602); GO_0034185 (EC: IPI, PMID: 11162594); GO_0034186 (EC: IPI, PMID: 11162594); GO_0034188 (EC: IDA, PMID: 16443932); GO_0034380 (EC: IMP, PMID: 10431236); GO_0034616 (EC: IEP, PMID: 15358760); GO_0038027 (EC: IDA, PMID: 16443932); GO_0042157 (EC: TAS); GO_0042493 (EC: IEA); GO_0042632 (EC: IDA, PMID: 10431236); GO_0043691 (EC: IMP, PMID: 10431236); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0045121 (EC: IDA, PMID: 15469992); GO_0045332 (EC: IEA); GO_0045335 (EC: IDA, PMID: 15469992); GO_0050702 (EC: IMP, PMID: 11855831); GO_0055091 (EC: IMP, PMID: 16702602); GO_0055098 (EC: IEP, PMID: 15358760); GO_0060155 (EC: IMP, PMID: 15163665); GO_0071222 (EC: IEA); GO_0071300 (EC: IEA); GO_0071397 (EC: IEA) PMID: 7766993; 8088782; 9006906; 9731541; 10092505; 10431236; 10431237; 10431238; 10525055; 10533863; 10535983; 10706591; 10799318; 10884428; 10938021; 10970803; 11086027; 11162594; 11238261; 11257260; 11257261; 11279031; 11349008; 11352567; 11476961; 11476965; 11700048; 11719471; 11752403; 11785958; 11809185; 11855831; 11861672; 11864601; 11893753; 11929608; 11940086; 11950847; 12009425; 12032171; 12054535; 12084722; 12093886; 12111371; 12151852; 12176027; 12196520; 12204794; 12226704; 12235128; 12359250; 12426219; 12477932; 12505994; 12509412; 12511593; 12535741; 12551894; 12562845; 12576507; 12600718; 12600975; 12615681; 12624133; 12700893; 12706378; 12709788; 12730295; 12763760; 12804586; 12813037; 12860256; 12869555; 12870173; 12928428; 12952980; 12966036; 14559902; 14560020; 14570867; 14576201; 14644402; 14660648; 14668333; 14681836; 14701812; 14701824; 14701850; 14702039; 14722086; 14734645; 14747463; 14754908; 14767869; 14962947; 14967052; 14967823; 14986172; 14993242; 15024730; 15033469; 15066991; 15102890; 15123239; 15135251; 15140889; 15158913; 15163665; 15201080; 15218032; 15262183; 15280376; 15288432; 15292375; 15297675; 15340333; 15358117; 15358760; 15469992; 15492319; 15500734; 15520867; 15528463; 15528481; 15574409; 15649702; 15657615; 15696473; 15721294; 15774904; 15817453; 15829498; 15851589; 15890646; 15905177; 15930518; 15935359; 15951431; 15952113; 15958302; 15961705; 15983222; 16009332; 16030523; 16055210; 16080812; 16086925; 16118212; 16120575; 16126721; 16157450; 16166555; 16192269; 16192270; 16192271; 16192272; 16192273; 16192274; 16192275; 16192276; 16192277; 16192278; 16192279; 16192281; 16192282; 16192283; 16192284; 16192285; 16192286; 16192287; 16192288; 16192289; 16192290; 16192291; 16192292; 16207713; 16226177; 16235041; 16254209; 16313984; 16343503; 16410457; 16418537; 16429166; 16443932; 16446539; 16456089; 16497665; 16498633; 16500904; 16505586; 16542392; 16596262; 16702602; 16709568; 16725228; 16730733; 16763159; 16770077; 16806233; 16806540; 16825673; 16855366; 16870193; 16873719; 16879828; 16901265; 16902247; 16928680; 17001213; 17020879; 17070530; 17076584; 17082211; 17113061; 17121837; 17135302; 17135600; 17196163; 17205124; 17241464; 17268197; 17287470; 17305370; 17324514; 17335784; 17368464; 17372331; 17383594; 17407076; 17412755; 17430597; 17481640; 17510466; 17510946; 17510949; 17521614; 17550732; 17553166; 17556657; 17604270; 17608096; 17656736; 17689273; 17690481; 17700364; 17710129; 17855807; 17923263; 17951323; 17991739; 17992631; 18003760; 18057374; 18097620; 18164264; 18193043; 18193044; 18199144; 18215356; 18218626; 18219093; 18220685; 18239666; 18252847; 18287097; 18343215; 18354102; 18385134; 18468402; 18484747; 18490524; 18523221; 18566305; 18583707; 18617649; 18621447; 18640393; 18660489; 18676680; 18706283; 18711208; 18762171; 18767813; 18776170; 18782226; 18782758; 18789440; 18803945; 18805791; 18820007; 18841006; 18927311; 18927546; 18955690; 18996286; 19019193; 19056482; 19059534; 19060906; 19060911; 19070858; 19099922; 19131637; 19133158; 19148283; 19151332; 19168441; 19170196; 19170766; 19201410; 19201688; 19202195; 19258317; 19261092; 19268428; 19285487; 19287193; 19295162; 19304534; 19304576; 19336370; 19341173; 19343046; 19420105; 19446537; 19474452; 19489872; 19528336; 19530967; 19538231; 19553242; 19556522; 19556721; 19578796; 19589783; 19596329; 19606474; 19625176; 19656776; 19673941; 19692168; 19692220; 19721717; 19743957; 19765707; 19767535; 19773416; 19783654; 19828131; 19837407; 19878569; 19902402; 19913121; 19948975; 20031551; 20057170; 20064972; 20067955; 20079340; 20089670; 20093111; 20101560; 20103810; 20160193; 20167577; 20170916; 20173014; 20185793; 20188211; 20215580; 20227257; 20303467; 20338636; 20346718; 20348106; 20378541; 20379614; 20385819; 20385826; 20394740; 20395597; 20413849; 20418488; 20427018; 20430392; 20472936; 20479131; 20485864; 20506155; 20553836; 20571217; 20571754; 20595220; 20625316; 20628086; 20634891; 20643408; 20671065; 20679960; 20686565; 20691829; 20702810; 20714348; 20727372; 20731376; 20797885; 20800056; 20807164; 20835684; 20855565; 20864672; 20880529; 20951680; 20972250; 21111593; 21116278; 21117950; 21130966; 21247457; 21289254; 21300560; 21310416; 21315358; 21339300; 21347282; 21389634; 21447678; 21478209; 21489276; 21501700; 21501868; 21507939; 21520210; 21530801; 21575609; 21591583; 21601208; 21605865; 21613373; 21634116; 21643759; 21677398; 21734188; 21740892; 21749932; 21757691; 21763656; 21817095; 21829447; 21840005; 21846716; 21860089; 21875686; 21885853; 21909109; 21920460; 21951852; 21988832; 22028339; 22035022; 22074701; 22119192; 22170052; 22178419; 22190032; 22248050; 22262807; 22271762; 22282358; 22286219; 22311493; 22315319; 22377775; 22384526; 22389325; 22399527; 22418575; 22419126; 22425645; 22466164; 22498566; 22503545; 22516753; 22584245; 22610793; 22614118; 22668585; 22672264; 22750655; 22844345; 22889411; 22913458; 22916037; 22929031; 22959828; 22981231; 22982414; 22984509; 23049088; 23053993; 23103472; 23111454; 23132909; 23136402; 23139370; 23152888; 23179156; 23181436; 23204179; 23220274; 23233737; 23273975; 23275468; 23305686; 23381994; 23402987; 23479619; 23505323; 23519696; 23543682; 23564066; 23582768; 23598720; 23656756; 23705956; 23707398; 23868939; 23990020; 24024966; 24097981; 24135019; 24189493 ATP-binding cassette, sub-family A (ABC1), member 1 Ensembl:ENSG00000165029 HGNC:29 HPRD:02501 MIM:600046 Vega:OTTHUMG00000020417 ABCA1 Bin Zhao, Yue Liu, Oliver He ACEE ARACHE N-ACHE YT WEB: http://www.ncbi.nlm.nih.gov/gene ACHE acetylcholinesterase (Yt blood group) 43 7q22 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0001507 (EC: NAS, PMID: 1517212); GO_0001540 (EC: TAS, PMID: 11283752); GO_0001919 (EC: IEA); GO_0002076 (EC: IEP, PMID: 15454088); GO_0003990 (EC: IDA, PMID: 1517212); GO_0003990 (EC: IMP, PMID: 1517212); GO_0004104 (EC: IDA, PMID: 1517212); GO_0005515 (EC: IPI, PMID: 10800960); GO_0005518 (EC: IDA, PMID: 12524166); GO_0005576 (EC: IDA, PMID: 1517212); GO_0005576 (EC: TAS, PMID: 11283752); GO_0005605 (EC: NAS, PMID: 16289501); GO_0005615 (EC: IBA); GO_0005634 (EC: IEA); GO_0005788 (EC: IBA); GO_0005794 (EC: IDA, PMID: 15454088); GO_0005886 (EC: TAS); GO_0006260 (EC: TAS, PMID: 11283752); GO_0006581 (EC: IDA, PMID: 1517212); GO_0006644 (EC: TAS); GO_0006656 (EC: TAS); GO_0007155 (EC: IDA, PMID: 15454088); GO_0007155 (EC: TAS, PMID: 11283752); GO_0007268 (EC: TAS); GO_0007271 (EC: IBA); GO_0007399 (EC: TAS, PMID: 11283752); GO_0007416 (EC: IBA); GO_0007416 (EC: TAS, PMID: 11283752); GO_0007517 (EC: TAS, PMID: 11283752); GO_0008283 (EC: TAS, PMID: 11283752); GO_0009611 (EC: TAS, PMID: 11283752); GO_0009986 (EC: IBA); GO_0016020 (EC: IDA, PMID: 16262697); GO_0016787 (EC: IDA, PMID: 1517212); GO_0017171 (EC: IDA, PMID: 3954986); GO_0019695 (EC: IBA); GO_0030054 (EC: IEA); GO_0030424 (EC: IBA); GO_0030425 (EC: IBA); GO_0031225 (EC: IEA); GO_0031594 (EC: IBA); GO_0031623 (EC: IEA); GO_0032223 (EC: IC, PMID: 1517212); GO_0042136 (EC: TAS); GO_0042166 (EC: IDA, PMID: 8349597); GO_0042166 (EC: NAS, PMID: 1517212); GO_0042734 (EC: IBA); GO_0042803 (EC: IPI, PMID: 12524166); GO_0042803 (EC: NAS, PMID: 1517212); GO_0042982 (EC: TAS, PMID: 12769797); GO_0043236 (EC: IDA, PMID: 12524166); GO_0043621 (EC: IEA); GO_0044281 (EC: TAS); GO_0045202 (EC: IDA, PMID: 8460160); GO_0045211 (EC: IBA); GO_0045212 (EC: IEA); GO_0046474 (EC: TAS); GO_0048471 (EC: IDA, PMID: 14766237); GO_0048814 (EC: IBA); GO_0050714 (EC: TAS, PMID: 11283752); GO_0050770 (EC: IBA); GO_0051262 (EC: IEA); GO_0060041 (EC: IEA) PMID: 1380483; 1391965; 1517212; 1609795; 1744105; 1748670; 2263619; 2714437; 2734315; 3319614; 3954986; 7085778; 7836436; 8125298; 8248502; 8280063; 8299725; 8349597; 8449945; 8460160; 8488842; 9579781; 9640563; 9689136; 9811904; 9847074; 10800960; 10837146; 11002295; 11053835; 11239002; 11283752; 11799248; 11804574; 12009429; 12069617; 12081473; 12140295; 12427014; 12466963; 12477932; 12524166; 12548360; 12604711; 12609505; 12690205; 12769797; 12811800; 12851386; 12853948; 12928915; 12963741; 14766237; 15060281; 15078872; 15123727; 15161650; 15454088; 15459952; 15474030; 15488495; 15526038; 15629887; 15690550; 15715671; 15783300; 15974894; 15974920; 16213467; 16256091; 16256968; 16262697; 16289501; 16375580; 16429485; 16516310; 16801396; 16832351; 16909200; 16996687; 17192624; 17192630; 17192673; 17272501; 17320203; 17335779; 17370251; 17476278; 17503475; 17606622; 17702992; 17729290; 17948252; 17984143; 18161504; 18194455; 18215127; 18258603; 18299393; 18344198; 18454940; 18457821; 18470725; 18612832; 18769671; 18780301; 19019080; 19051205; 19086053; 19156168; 19185568; 19294450; 19327769; 19371630; 19371631; 19468687; 19730683; 19912576; 19913121; 20138030; 20156100; 20173328; 20193849; 20338155; 20356562; 20398640; 20398908; 20431033; 20433814; 20529763; 20602615; 20628086; 20883446; 20964587; 21274871; 21377978; 21473860; 21490949; 21493754; 21530001; 21576115; 21621296; 21730071; 21795704; 22142546; 22560633; 22805525; 22990020; 23047022; 23047027; 23063927; 23119107; 23440190; 23466605; 23583979; 23748235; 23897820; 23936791; 24249815; 24402754 acetylcholinesterase (Yt blood group) Ensembl:ENSG00000087085 HGNC:108 HPRD:00010 MIM:100740 Vega:OTTHUMG00000157033 ACHE Bin Zhao, Yue Liu, Oliver He ACONS HEL60 IREB1 IREBP IREBP1 IRP1 WEB: http://www.ncbi.nlm.nih.gov/gene ACO1 aconitase 1, soluble 48 RP11-334P12.1 9p21.1 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0003723 (EC: IDA, PMID: 1946430); GO_0003723 (EC: NAS, PMID: 1903202); GO_0003994 (EC: IDA, PMID: 1946430); GO_0005515 (EC: IPI, PMID: 19762596); GO_0005737 (EC: IDA); GO_0005737 (EC: NAS, PMID: 1738601); GO_0005739 (EC: IDA); GO_0005783 (EC: IDA, PMID: 16144863); GO_0005794 (EC: IDA, PMID: 16144863); GO_0005829 (EC: IDA, PMID: 16527810); GO_0006099 (EC: IEA); GO_0006101 (EC: IDA, PMID: 16527810); GO_0006417 (EC: IEA); GO_0006879 (EC: IEA); GO_0009791 (EC: IEA); GO_0010040 (EC: IDA, PMID: 8041788); GO_0030350 (EC: IDA, PMID: 8041788); GO_0046872 (EC: IEA); GO_0050892 (EC: IEA); GO_0051539 (EC: IDA, PMID: 16407072); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1738601; 1903202; 1946430; 2172968; 2771641; 8041788; 8262977; 8764614; 9020582; 10419470; 10944468; 11783942; 11812787; 12196178; 12477932; 12572667; 12855587; 12972614; 15099026; 15342556; 15349772; 15489334; 15543932; 15938636; 16027165; 16144863; 16344560; 16407072; 16424901; 16503547; 16527810; 17127713; 17200797; 17242182; 17244191; 17521334; 17604281; 17613866; 17877204; 18029348; 18262302; 19056867; 19688112; 19762596; 19762597; 20354189; 20558735; 20569198; 20574843; 20877624; 21139048; 21360641; 21832049; 21890473; 21906983; 21963094; 22020773; 22331484; 22502979; 22505724; 22544036; 22561531; 22863883; 22939629; 23000965; 23382691; 23615448; 23817740 aconitase 1, soluble Ensembl:ENSG00000122729 HGNC:117 HPRD:00013 MIM:100880 Vega:OTTHUMG00000019740 ACO1 Bin Zhao, Yue Liu, Oliver He ACTA ASMA CFTD CFTD1 CFTDM MPFD NEM1 NEM2 NEM3 WEB: http://www.ncbi.nlm.nih.gov/gene ACTA1 actin, alpha 1, skeletal muscle 58 RP5-1068B5.2 1q42.13 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001725 (EC: IDA, PMID: 15198992); GO_0005200 (EC: TAS, PMID: 10508519); GO_0005515 (EC: IPI, PMID: 12849983); GO_0005524 (EC: TAS, PMID: 10508519); GO_0005615 (EC: IDA); GO_0005829 (EC: TAS); GO_0005865 (EC: IDA, PMID: 15198992); GO_0005884 (EC: IDA, PMID: 12849983); GO_0006936 (EC: TAS, PMID: 10508519); GO_0009612 (EC: IEA); GO_0009991 (EC: IEA); GO_0010226 (EC: IEA); GO_0015629 (EC: IMP, PMID: 15198992); GO_0016049 (EC: IEA); GO_0017022 (EC: TAS, PMID: 10508519); GO_0030017 (EC: IDA, PMID: 1423520); GO_0030049 (EC: TAS); GO_0030240 (EC: IMP, PMID: 11333380); GO_0043503 (EC: IEA); GO_0043531 (EC: TAS, PMID: 10508519); GO_0048545 (EC: IEA); GO_0048741 (EC: ISS); GO_0070062 (EC: IDA, PMID: 19199708); GO_0072562 (EC: IDA) PMID: 648524; 1074709; 1383230; 1423520; 1540415; 1544421; 1808202; 1907279; 1991513; 2161834; 2395459; 2455687; 2907503; 2936753; 3793760; 3842206; 6190133; 6865942; 6893424; 7503723; 7642559; 7680654; 7703225; 7780165; 7816144; 7820861; 7908020; 7908614; 8258301; 8395021; 8399167; 8413665; 8416954; 8422497; 8567732; 8612804; 8997639; 8999969; 9153421; 9199170; 9214391; 9251807; 9298982; 9417078; 9490638; 9512503; 9645951; 9668039; 9695962; 9724539; 9792688; 9832551; 9841925; 9852149; 10072583; 10224093; 10320340; 10366597; 10438535; 10491393; 10508519; 10556093; 10559237; 10564664; 10575001; 10581178; 10583954; 10601340; 10628374; 10666339; 10793131; 10806479; 10882740; 10958653; 10984435; 11018051; 11027608; 11053353; 11071908; 11090452; 11102443; 11106625; 11166164; 11171322; 11259305; 11297527; 11309382; 11333380; 11415434; 11429692; 11438522; 11441066; 11461920; 11468283; 11481347; 11524436; 11536049; 11580270; 11583571; 11687588; 11691822; 11701614; 11702052; 11707283; 11795944; 11812134; 11821948; 11839310; 11850458; 11877456; 11889126; 11897493; 11950878; 11969288; 12006649; 12033495; 12044158; 12048248; 12062430; 12119014; 12127568; 12163017; 12210873; 12383268; 12384700; 12388543; 12417592; 12417594; 12438125; 12438242; 12466270; 12475945; 12477932; 12480535; 12534372; 12554937; 12571245; 12665555; 12695497; 12714565; 12721663; 12849983; 12857853; 14506234; 14507647; 14532270; 14576350; 14592989; 14594945; 14634002; 14640694; 14668487; 14676314; 14684598; 14688263; 14690596; 14694110; 14702039; 14966270; 15059972; 15072110; 15107502; 15149849; 15152255; 15198992; 15236405; 15336687; 15454575; 15468086; 15489334; 15494313; 15507486; 15520409; 15558034; 15679046; 15772115; 16009940; 16051665; 16427282; 16461343; 16501887; 16526095; 16568092; 16751776; 16916647; 16945536; 17010111; 17082770; 17194691; 17194709; 17203973; 17266347; 17360745; 17361185; 17387733; 17411366; 17504171; 17573780; 17620599; 18063690; 18443296; 18461503; 18662664; 18775311; 18781797; 18976909; 19002257; 19150851; 19199708; 19233165; 19380743; 19383239; 19389844; 19454010; 19553474; 19562689; 19634497; 19635823; 19639585; 19710135; 19819966; 19883584; 19934221; 19948975; 20100475; 20147394; 20169155; 20179953; 20201926; 20301436; 20301465; 20305087; 20332100; 20378355; 20388088; 20391533; 20452215; 20630939; 20639865; 20686692; 20716950; 20718862; 20809254; 20826790; 20972266; 21079800; 21080425; 21108927; 21139048; 21145461; 21151833; 21199870; 21203488; 21319273; 21340023; 21385873; 21464227; 21514153; 21606541; 21691712; 21723825; 21764995; 21824169; 21890473; 21906983; 21912905; 21917091; 21923909; 21931536; 21963094; 21975552; 21987572; 21994736; 22004035; 22017400; 22028271; 22031939; 22053931; 22081313; 22209233; 22362758; 22465675; 22505724; 22535526; 22537596; 22863883; 22989508; 23000965; 23042265; 23071671; 23174700; 23176180; 23190606; 23246001; 23247112; 23376163; 23420843; 23656990; 23831272; 24255178; 24313005 actin, alpha 1, skeletal muscle Ensembl:ENSG00000143632 HGNC:129 HPRD:00030 MIM:102610 Vega:OTTHUMG00000038006 ACTA1 Bin Zhao, Yue Liu, Oliver He AD10 AD18 CD156c HsT18717 MADM RAK kuz WEB: http://www.ncbi.nlm.nih.gov/gene ADAM10 ADAM metallopeptidase domain 10 102 15q22 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0001701 (EC: ISS); GO_0004175 (EC: ISS); GO_0004222 (EC: IMP, PMID: 19114711); GO_0004222 (EC: NAS, PMID: 8694785); GO_0005102 (EC: NAS, PMID: 12176995); GO_0005178 (EC: NAS, PMID: 8694785); GO_0005515 (EC: IPI, PMID: 10527948); GO_0005634 (EC: ISS); GO_0005737 (EC: ISS); GO_0005794 (EC: IDA, PMID: 12475894); GO_0005798 (EC: IDA, PMID: 12475894); GO_0005886 (EC: TAS); GO_0006468 (EC: ISS); GO_0006509 (EC: IDA, PMID: 12714508); GO_0006509 (EC: IMP, PMID: 17965014); GO_0007162 (EC: IDA, PMID: 12714508); GO_0007162 (EC: NAS, PMID: 8694785); GO_0007173 (EC: TAS); GO_0007219 (EC: ISS); GO_0007219 (EC: TAS); GO_0007220 (EC: TAS); GO_0007229 (EC: NAS, PMID: 8694785); GO_0007267 (EC: NAS, PMID: 12714508); GO_0008237 (EC: IDA, PMID: 12475894); GO_0008237 (EC: IMP, PMID: 12535668); GO_0008237 (EC: TAS); GO_0008270 (EC: IEA); GO_0008284 (EC: IMP, PMID: 18373975); GO_0009986 (EC: IDA, PMID: 12475894); GO_0010820 (EC: IMP, PMID: 18373975); GO_0014069 (EC: IEA); GO_0016021 (EC: NAS, PMID: 8694785); GO_0017124 (EC: IEA); GO_0019901 (EC: ISS); GO_0022617 (EC: TAS); GO_0030198 (EC: TAS); GO_0030307 (EC: IMP, PMID: 18373975); GO_0030335 (EC: IMP, PMID: 18373975); GO_0030574 (EC: TAS); GO_0034612 (EC: IDA, PMID: 11831872); GO_0042117 (EC: IMP, PMID: 11831872); GO_0042803 (EC: ISS); GO_0051088 (EC: IMP, PMID: 18676862); GO_0051089 (EC: IDA, PMID: 12714508); GO_0070062 (EC: IDA) PMID: 7593158; 7822279; 8694785; 9016778; 9305925; 9344679; 9441766; 9618175; 10423016; 10527948; 10737800; 10958785; 11477090; 11511685; 11741929; 11786905; 11831872; 11839628; 12080182; 12176995; 12438920; 12475894; 12477932; 12535668; 12568494; 12590602; 12629514; 12665519; 12714508; 12730960; 12782344; 12794186; 12815056; 12832423; 12960155; 14627705; 14636066; 14702039; 14707550; 15182369; 15280379; 15280425; 15300588; 15507448; 15905513; 15958533; 16239146; 16263114; 16263699; 16309826; 16344560; 16390331; 16627989; 16648485; 16735514; 16751190; 16806063; 16942750; 17170699; 17187903; 17192395; 17290285; 17557115; 17699774; 17727679; 17895248; 17965014; 18074395; 18187620; 18200054; 18215140; 18355445; 18373975; 18381078; 18420943; 18480749; 18514661; 18603587; 18642355; 18676862; 18781797; 18952609; 18971959; 18979631; 18981120; 19091752; 19114711; 19144697; 19260824; 19278423; 19344981; 19357285; 19394555; 19426159; 19435795; 19541935; 19564338; 19587294; 19603142; 19608551; 19632330; 19665015; 19667218; 19672558; 19704010; 19783906; 19823572; 19826051; 19865098; 19913121; 20059578; 20070888; 20136654; 20348102; 20371803; 20381196; 20443867; 20624979; 20628086; 20676056; 20677014; 20711474; 20814017; 20863729; 21103979; 21123580; 21171968; 21196064; 21259244; 21368228; 21402705; 21441465; 21569301; 21576249; 21611732; 21625236; 21695060; 21804545; 21876729; 21906983; 21956108; 21959176; 21969210; 22006996; 22065584; 22116825; 22167753; 22268729; 22404213; 22474035; 22505724; 22572541; 22586143; 22613720; 22641052; 22689693; 22770404; 22923171; 22933306; 22939629; 22940701; 22965144; 23035126; 23124962; 23192951; 23306532; 23429442; 23460612; 23526433; 23546882; 23579328; 23666529; 23674691; 23676497; 23720309; 23746173; 23936798; 24055016; 24055471; 24121505; 24165480; 24189063; 24250222; 24286866 ADAM metallopeptidase domain 10 Alzpathway: NPD1 leading to ADAM10; Source: https://pubmed.ncbi.nlm.nih.gov/21431475/ Ensembl:ENSG00000137845 HGNC:188 HPRD:03723 MIM:602192 Vega:OTTHUMG00000132633 ADAM10 Bin Zhao, Yue Liu, Oliver He BARK1 BETA-ARK1 GRK2 WEB: http://www.ncbi.nlm.nih.gov/gene ADRBK1 adrenergic, beta, receptor kinase 1 156 11q13.1 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0002029 (EC: ISS); GO_0003108 (EC: IMP, PMID: 15051637); GO_0004672 (EC: ISS); GO_0004703 (EC: ISS); GO_0005515 (EC: IPI, PMID: 17006543); GO_0005524 (EC: IEA); GO_0005737 (EC: IDA, PMID: 17986524); GO_0005829 (EC: TAS); GO_0005886 (EC: TAS); GO_0007165 (EC: TAS); GO_0007173 (EC: TAS); GO_0007202 (EC: TAS); GO_0007213 (EC: ISS); GO_0007217 (EC: IDA, PMID: 17986524); GO_0007507 (EC: IEA); GO_0008543 (EC: TAS); GO_0016020 (EC: ISS); GO_0018105 (EC: ISS); GO_0018107 (EC: IEA); GO_0031623 (EC: IDA); GO_0031694 (EC: ISS); GO_0031755 (EC: IDA, PMID: 19306925); GO_0033605 (EC: ISS); GO_0038032 (EC: IEA); GO_0045087 (EC: TAS); GO_0045988 (EC: IMP, PMID: 15051637); GO_0047696 (EC: IEA); GO_0048011 (EC: TAS); GO_0060048 (EC: IMP, PMID: 15051637) PMID: 1339451; 2037065; 7836371; 7876239; 8195124; 8662816; 8885248; 9211925; 9446593; 9501202; 9618528; 9826657; 10085129; 10085131; 10091590; 10379886; 10467231; 10574913; 10617630; 10722682; 10727525; 10744734; 10754297; 10852916; 10858453; 10861009; 10884381; 10896954; 11040053; 11042191; 11278469; 11309381; 11517230; 11762794; 12107237; 12123746; 12130691; 12130708; 12163475; 12351722; 12379128; 12381737; 12435819; 12456365; 12477932; 12486133; 12507501; 12552191; 12624098; 12639913; 12679936; 12750365; 12885252; 14557268; 14654844; 14729942; 14997482; 15051637; 15097244; 15271984; 15471870; 15489334; 15542600; 15569306; 15618519; 15620700; 15653687; 15778405; 15843435; 15870073; 15919661; 16077899; 16081410; 16091361; 16094730; 16121194; 16356165; 16605244; 16725308; 16849637; 16920721; 16984558; 17000469; 17006543; 17008309; 17055984; 17102134; 17146290; 17256744; 17276003; 17482545; 17544362; 17548351; 17893145; 17986524; 17998459; 18369319; 18425130; 18451066; 18463167; 18511496; 18854154; 18976975; 19257866; 19292735; 19306925; 19338266; 19400979; 19487588; 19620130; 19815545; 19846537; 19906838; 19913121; 19953087; 20080565; 20335112; 20443852; 20443948; 20460384; 20468064; 20493668; 20501412; 20627936; 20628086; 20684281; 20696855; 20730384; 20807772; 20814022; 20861385; 21081496; 21127457; 21283592; 21357420; 21464134; 21473908; 21705320; 21784156; 21890473; 21900206; 21940795; 21952200; 21983013; 21988832; 22089113; 22193721; 22196842; 22375000; 22505724; 22589388; 22731384; 22735336; 23029581; 23076141; 23082996; 23139825; 23208013; 23221335; 23312955; 23362259; 23455922; 23460259; 23467820; 23494575; 23705503; 23734232; 23940030; 24064210; 24135140; 24169548 adrenergic, beta, receptor kinase 1 Ensembl:ENSG00000173020 HGNC:289 HPRD:00182 MIM:109635 Vega:OTTHUMG00000167104 ADRBK1 Bin Zhao, Yue Liu, Oliver He RAGE WEB: http://www.ncbi.nlm.nih.gov/gene AGER advanced glycosylation end product-specific receptor 177 DAMA-358M23.4 6p21.3 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0004872 (EC: TAS, PMID: 8751438); GO_0004888 (EC: TAS, PMID: 1378843); GO_0005515 (EC: IPI, PMID: 16061848); GO_0005576 (EC: IEA); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 1378843); GO_0006954 (EC: IEA); GO_0007166 (EC: TAS, PMID: 10835680); GO_0009611 (EC: TAS, PMID: 10399917); GO_0031175 (EC: IGI, PMID: 10391939); GO_0042802 (EC: IPI); GO_0044548 (EC: IPI, PMID: 15033494); GO_0045087 (EC: TAS); GO_0050930 (EC: IEA); GO_0051092 (EC: IDA, PMID: 10391939) PMID: 1378843; 7713518; 7835890; 7887450; 8751438; 8787669; 8889548; 9195959; 9734395; 9812979; 10391939; 10399917; 10521570; 10531386; 10601334; 10835680; 11007787; 11282423; 11334430; 11375354; 11457670; 11586486; 11700025; 11739380; 11811511; 11884895; 11961018; 12029499; 12070776; 12475402; 12477623; 12477932; 12495433; 12579287; 12598893; 12606536; 12618340; 12651613; 12671312; 12837757; 12859967; 12909002; 12935895; 12941744; 14501001; 14571699; 14574404; 14580673; 14595542; 14617629; 14656967; 14704946; 14747204; 15009731; 15019601; 15033494; 15052533; 15053925; 15127201; 15155381; 15170618; 15180953; 15203887; 15213278; 15239215; 15247020; 15289604; 15448098; 15489334; 15539404; 15547674; 15555779; 15599399; 15663911; 15666359; 15666591; 15748606; 15790669; 15798956; 15803111; 15893388; 15896660; 15911356; 15915542; 15926115; 15930093; 15942078; 15942086; 15944249; 15986224; 16037279; 16052547; 16061848; 16127291; 16159602; 16166741; 16271939; 16286548; 16305072; 16374460; 16440015; 16493495; 16644647; 16716307; 16728681; 16788244; 16847147; 16899960; 16954185; 16954682; 16969646; 16969649; 17004092; 17024691; 17035340; 17158877; 17170388; 17172923; 17218539; 17224333; 17237617; 17343760; 17345061; 17355942; 17405935; 17425804; 17434489; 17474147; 17497647; 17508727; 17512509; 17536039; 17549666; 17560613; 17588956; 17592553; 17593216; 17601350; 17613396; 17639302; 17640970; 17660747; 17661837; 17700210; 17714874; 17924846; 18032526; 18046662; 18050248; 18058469; 18078623; 18079485; 18079965; 18080716; 18089847; 18179750; 18231794; 18245812; 18256374; 18279703; 18279705; 18302220; 18322992; 18339893; 18355449; 18421017; 18427074; 18431028; 18438937; 18458846; 18477569; 18480271; 18519797; 18550199; 18575614; 18576917; 18593464; 18595673; 18603587; 18606705; 18615900; 18645306; 18657529; 18660489; 18667420; 18689872; 18698218; 18701333; 18775683; 18777492; 18789567; 18796298; 18825489; 18854308; 18922799; 18926539; 18948101; 18952609; 18977241; 18987644; 19005067; 19023628; 19032093; 19061941; 19071026; 19087540; 19088375; 19103440; 19129693; 19133252; 19143681; 19143821; 19167759; 19183936; 19201044; 19204726; 19217461; 19217891; 19248116; 19252206; 19275767; 19277685; 19284577; 19285601; 19332646; 19376511; 19380603; 19380826; 19386136; 19405075; 19439163; 19440065; 19448391; 19451748; 19501570; 19530996; 19542745; 19571577; 19576587; 19578796; 19587357; 19591173; 19616266; 19635564; 19659809; 19672558; 19679874; 19766904; 19786934; 19815443; 19820033; 19822091; 19834494; 19851445; 19876719; 19890027; 19902324; 19906677; 19909734; 19910580; 19913121; 19924100; 19944695; 19945761; 19948975; 19998499; 20010834; 20010835; 20023238; 20028692; 20028726; 20031245; 20040351; 20051912; 20074734; 20093728; 20112183; 20171262; 20185929; 20215707; 20353610; 20359119; 20359471; 20372816; 20398646; 20410680; 20414834; 20485444; 20492604; 20504772; 20507991; 20512925; 20522598; 20537326; 20541603; 20567859; 20568058; 20578941; 20595148; 20627100; 20628086; 20630999; 20631986; 20650982; 20668462; 20684319; 20685137; 20701913; 20726326; 20732329; 20739563; 20817881; 20847094; 20928981; 20943659; 20947022; 21067489; 21067572; 21072897; 21080832; 21086782; 21089112; 21115116; 21126167; 21127710; 21137019; 21197704; 21208063; 21211520; 21254649; 21254849; 21257730; 21278261; 21282351; 21297263; 21298413; 21303685; 21311028; 21316677; 21317562; 21325454; 21357189; 21365018; 21389696; 21432860; 21450080; 21450369; 21472666; 21472688; 21511691; 21511948; 21512281; 21521347; 21527578; 21540233; 21565706; 21576827; 21609778; 21617715; 21680901; 21706016; 21724696; 21736957; 21749686; 21767223; 21771973; 21829704; 21832049; 21844192; 21861709; 21865159; 21871056; 21872861; 21906738; 21914366; 21920897; 21941211; 21945853; 21947243; 21947881; 21965014; 21978883; 21990362; 22012330; 22025532; 22027013; 22072229; 22097731; 22114731; 22116960; 22137663; 22146151; 22154374; 22189627; 22194616; 22206663; 22211895; 22212601; 22229442; 22264245; 22315985; 22337892; 22339587; 22353366; 22354095; 22366088; 22382005; 22386596; 22402134; 22405771; 22417726; 22427038; 22460069; 22475522; 22490537; 22509024; 22509345; 22513366; 22553402; 22578261; 22633675; 22652038; 22771726; 22777515; 22785051; 22835520; 22837190; 22843047; 22860017; 22860029; 22863784; 22900949; 22920235; 22960399; 22964273; 22965881; 22966766; 22983919; 22987041; 22989605; 23071492; 23091285; 23103427; 23144152; 23182709; 23206470; 23228658; 23236395; 23252485; 23275625; 23284291; 23284645; 23288172; 23318458; 23325627; 23331756; 23340902; 23421467; 23426492; 23432638; 23466064; 23508966; 23525442; 23527722; 23535732; 23545311; 23559480; 23571222; 23593165; 23628898; 23693020; 23712703; 23721855; 23729200; 23755764; 23759926; 23894685; 23911608; 23947473; 23954397; 23973487; 24081950; 24188108; 24231387; 24260107; 24273313 advanced glycosylation end product-specific receptor Ensembl:ENSG00000204305 HGNC:320 HPRD:02568 MIM:600214 Vega:OTTHUMG00000031120 AGER Bin Zhao, Yue Liu, Oliver He AKT CWS6 PKB PKB-ALPHA PRKBA RAC RAC-ALPHA WEB: http://www.ncbi.nlm.nih.gov/gene AKT1 v-akt murine thymoma viral oncogene homolog 1 207 14q32.32 20140408 9606 14 protein-coding Official from a nomenclature committee GO_0000060 (EC: IMP, PMID: 16280327); GO_0001649 (EC: IEA); GO_0001893 (EC: IEA); GO_0001934 (EC: IDA, PMID: 19057511); GO_0001938 (EC: IMP, PMID: 19850054); GO_0004672 (EC: TAS, PMID: 10570282); GO_0004674 (EC: IDA, PMID: 10102273); GO_0004674 (EC: TAS); GO_0005080 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11154276); GO_0005524 (EC: IC, PMID: 11994271); GO_0005524 (EC: IDA, PMID: 16540465); GO_0005547 (EC: IDA, PMID: 19203586); GO_0005634 (EC: IDA); GO_0005634 (EC: TAS); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA, PMID: 19203586); GO_0005737 (EC: ISS); GO_0005737 (EC: TAS); GO_0005819 (EC: IEA); GO_0005829 (EC: IDA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 14749367); GO_0005886 (EC: TAS); GO_0005978 (EC: IEA); GO_0005979 (EC: IMP, PMID: 8940145); GO_0006006 (EC: IEA); GO_0006412 (EC: IEA); GO_0006417 (EC: IEA); GO_0006464 (EC: TAS, PMID: 10570282); GO_0006468 (EC: IDA, PMID: 11994271); GO_0006469 (EC: IMP, PMID: 9373175); GO_0006469 (EC: ISS); GO_0006809 (EC: TAS, PMID: 10376602); GO_0006915 (EC: TAS); GO_0006924 (EC: IMP, PMID: 14749367); GO_0006954 (EC: IEA); GO_0007165 (EC: TAS); GO_0007173 (EC: TAS); GO_0007186 (EC: TAS, PMID: 10570282); GO_0007281 (EC: IEA); GO_0007568 (EC: IEA); GO_0007596 (EC: TAS); GO_0008283 (EC: TAS); GO_0008286 (EC: IMP, PMID: 8978681); GO_0008543 (EC: TAS); GO_0008637 (EC: IEA); GO_0009408 (EC: TAS, PMID: 10958679); GO_0010467 (EC: TAS); GO_0010507 (EC: IMP, PMID: 18387192); GO_0010748 (EC: IMP, PMID: 16814735); GO_0010765 (EC: IEA); GO_0010907 (EC: IMP, PMID: 16814735); GO_0010951 (EC: IMP, PMID: 18387192); GO_0010975 (EC: ISS); GO_0015630 (EC: IDA); GO_0015758 (EC: IEA); GO_0016070 (EC: TAS); GO_0016071 (EC: TAS); GO_0016301 (EC: IDA, PMID: 14749367); GO_0016310 (EC: IDA); GO_0016567 (EC: IEA); GO_0018105 (EC: IDA, PMID: 16139227); GO_0019899 (EC: ISS); GO_0030030 (EC: IEA); GO_0030154 (EC: TAS); GO_0030163 (EC: IEA); GO_0030168 (EC: TAS); GO_0030212 (EC: IEA); GO_0030235 (EC: IMP, PMID: 10376603); GO_0030307 (EC: IDA, PMID: 19203586); GO_0030334 (EC: IMP, PMID: 19934221); GO_0030334 (EC: TAS); GO_0031018 (EC: TAS); GO_0031295 (EC: TAS); GO_0031659 (EC: IDA, PMID: 18483258); GO_0031999 (EC: IMP, PMID: 16814735); GO_0032094 (EC: IEA); GO_0032270 (EC: ISS); GO_0032287 (EC: IEA); GO_0032436 (EC: IEA); GO_0032869 (EC: IMP, PMID: 16814735); GO_0032869 (EC: ISS); GO_0033138 (EC: IDA, PMID: 19667065); GO_0034405 (EC: IMP, PMID: 10376603); GO_0035556 (EC: IDA, PMID: 14749367); GO_0038095 (EC: TAS); GO_0042593 (EC: IEA); GO_0042640 (EC: IEA); GO_0042802 (EC: IPI, PMID: 7891724); GO_0043065 (EC: IEA); GO_0043066 (EC: IDA, PMID: 19203586); GO_0043154 (EC: ISS); GO_0043325 (EC: IDA, PMID: 19203586); GO_0043491 (EC: IEA); GO_0043536 (EC: IDA); GO_0044281 (EC: TAS); GO_0045087 (EC: TAS); GO_0045429 (EC: IMP, PMID: 10376603); GO_0045600 (EC: IMP, PMID: 8940145); GO_0045725 (EC: IMP, PMID: 16814735); GO_0045725 (EC: NAS, PMID: 17925406); GO_0045792 (EC: IEA); GO_0045861 (EC: IMP, PMID: 18387192); GO_0045907 (EC: IEA); GO_0045944 (EC: IEA); GO_0046209 (EC: TAS); GO_0046326 (EC: IMP, PMID: 16814735); GO_0046329 (EC: IEA); GO_0046777 (EC: TAS, PMID: 16280327); GO_0046889 (EC: IMP, PMID: 8940145); GO_0048009 (EC: IMP, PMID: 8978681); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0050999 (EC: TAS); GO_0051000 (EC: IMP, PMID: 10376603); GO_0051091 (EC: IDA, PMID: 19057511); GO_0051146 (EC: IEA); GO_0060644 (EC: TAS); GO_0060709 (EC: IEA); GO_0060716 (EC: IEA); GO_0061024 (EC: TAS); GO_0070141 (EC: IDA, PMID: 18483258); GO_0071260 (EC: IEA); GO_0071364 (EC: IEA); GO_0071456 (EC: IEA); GO_0071889 (EC: IPI, PMID: 10102273); GO_0090004 (EC: IMP, PMID: 8940145); GO_0090201 (EC: ISS); GO_0097193 (EC: TAS); GO_0097194 (EC: IEA); GO_1900740 (EC: TAS); GO_1901976 (EC: TAS); GO_1902176 (EC: NAS, PMID: 16604263); GO_2001240 (EC: TAS, PMID: 10748004) PMID: 1533586; 1718748; 1851997; 3037531; 3384441; 7774014; 7891724; 8524413; 8940145; 8978681; 9005852; 9019819; 9312003; 9368760; 9373175; 9381178; 9394803; 9395488; 9512493; 9736715; 9768361; 9812896; 9829964; 9973250; 10082674; 10085094; 10102273; 10217147; 10224060; 10226025; 10358014; 10376602; 10376603; 10438924; 10454575; 10485710; 10485711; 10490823; 10490848; 10491192; 10497255; 10527852; 10542266; 10570282; 10576742; 10617634; 10635328; 10698680; 10748004; 10833263; 10866658; 10869359; 10869418; 10872470; 10896934; 10910062; 10926925; 10930578; 10958679; 10983986; 10995457; 11035810; 11042204; 11116148; 11139588; 11154276; 11154281; 11156376; 11156964; 11162552; 11208609; 11274386; 11278835; 11278894; 11313365; 11313479; 11404460; 11410590; 11410591; 11425855; 11438723; 11445557; 11500364; 11504915; 11508278; 11509608; 11535620; 11546794; 11579209; 11583630; 11585925; 11598301; 11689711; 11696579; 11707444; 11707464; 11710897; 11715018; 11723139; 11756412; 11773441; 11777913; 11782427; 11809791; 11825911; 11828257; 11855836; 11877387; 11884598; 11902142; 11903042; 11923280; 11956222; 11960368; 11976320; 11994271; 11994280; 12009899; 12011046; 12042314; 12062056; 12062094; 12070137; 12077256; 12112022; 12124386; 12138087; 12138205; 12145204; 12149249; 12150915; 12167664; 12167717; 12176337; 12176338; 12176997; 12194869; 12218048; 12244133; 12244301; 12244302; 12244303; 12297295; 12376533; 12393747; 12438239; 12446767; 12446787; 12446789; 12458207; 12477932; 12524439; 12527373; 12529294; 12535517; 12586360; 12592338; 12621049; 12637511; 12722480; 12727836; 12734380; 12741986; 12750378; 12757707; 12768030; 12782295; 12783873; 12791994; 12808085; 12808093; 12853467; 12874217; 12888921; 12919677; 12952968; 12972603; 14499622; 14500673; 14505491; 14520710; 14523021; 14534536; 14560023; 14566704; 14568991; 14611643; 14612949; 14623889; 14625285; 14636889; 14645242; 14645548; 14647146; 14657000; 14679206; 14702039; 14713953; 14742298; 14749367; 14749388; 14749719; 14755253; 14761976; 14970221; 14973226; 14985374; 15001646; 15010337; 15016818; 15026145; 15047604; 15047866; 15060171; 15067058; 15102693; 15115729; 15118108; 15136501; 15146197; 15149849; 15156201; 15173318; 15183529; 15187088; 15187138; 15194442; 15203190; 15217935; 15231831; 15242771; 15262962; 15262978; 15263908; 15271644; 15283964; 15284024; 15306850; 15316080; 15326564; 15331441; 15342781; 15342917; 15385469; 15388791; 15389633; 15459205; 15465021; 15467757; 15470047; 15475446; 15489334; 15492215; 15522255; 15525681; 15527798; 15533996; 15539407; 15545269; 15545271; 15545519; 15546863; 15572689; 15574337; 15580267; 15581622; 15607733; 15609321; 15616007; 15665327; 15665818; 15668028; 15678105; 15688030; 15689238; 15705789; 15710591; 15718470; 15722337; 15723049; 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23041284; 23043959; 23046567; 23047954; 23060458; 23069661; 23082158; 23092880; 23092893; 23095753; 23097134; 23107319; 23112296; 23125486; 23127761; 23133535; 23134728; 23135917; 23135998; 23138182; 23147115; 23167739; 23169238; 23176396; 23182717; 23185040; 23188060; 23192081; 23192871; 23195959; 23200933; 23205493; 23208492; 23225414; 23227138; 23235274; 23236232; 23237847; 23246288; 23249714; 23255608; 23261389; 23271397; 23272133; 23280503; 23297824; 23300340; 23300741; 23303682; 23314850; 23315288; 23318419; 23319332; 23321169; 23325864; 23334667; 23338526; 23340251; 23340270; 23348505; 23352210; 23354687; 23354912; 23379509; 23380710; 23383273; 23384770; 23386617; 23389849; 23409016; 23409128; 23417403; 23418602; 23419514; 23421998; 23424671; 23429328; 23430973; 23434580; 23437141; 23440515; 23442539; 23444215; 23457304; 23457334; 23459592; 23463506; 23463670; 23474367; 23499907; 23504323; 23507869; 23511556; 23512990; 23521913; 23525579; 23546174; 23546450; 23546602; 23547889; 23553960; 23558942; 23561972; 23563091; 23563706; 23567263; 23574721; 23580656; 23583197; 23603894; 23613227; 23615537; 23615713; 23624506; 23625205; 23626817; 23629924; 23639623; 23640046; 23667466; 23677479; 23684008; 23685151; 23686362; 23708780; 23710442; 23710710; 23711387; 23724143; 23725225; 23726842; 23728071; 23740762; 23741320; 23742646; 23743572; 23754751; 23757022; 23765166; 23786162; 23788636; 23791833; 23792459; 23792604; 23796964; 23811754; 23812726; 23824745; 23832540; 23838801; 23840064; 23841076; 23843462; 23852728; 23863161; 23867821; 23869765; 23876532; 23884311; 23884447; 23884910; 23886157; 23896866; 23898095; 23923067; 23934627; 23996929; 24001613; 24005670; 24015256; 24030155; 24081328; 24095799; 24099783; 24113181; 24120917; 24152492; 24154876; 24157255; 24225136; 24297901; 24314632; 24321521; 24458280; 24600969 v-akt murine thymoma viral oncogene homolog 1 Ensembl:ENSG00000142208 HGNC:391 HPRD:01261 MIM:164730 Vega:OTTHUMG00000170795 AKT1 Bin Zhao, Yue Liu, Oliver He PRO0883 PRO0903 PRO1341 WEB: http://www.ncbi.nlm.nih.gov/gene ALB albumin 213 GIG20 4q13.3 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0001895 (EC: IEP); GO_0002576 (EC: TAS); GO_0003677 (EC: IDA, PMID: 16405401); GO_0005504 (EC: IDA, PMID: 16289007); GO_0005504 (EC: NAS, PMID: 9731778); GO_0005507 (EC: NAS, PMID: 14726550); GO_0005515 (EC: IPI, PMID: 16099937); GO_0005576 (EC: NAS, PMID: 14718574); GO_0005576 (EC: TAS); GO_0005604 (EC: IEA); GO_0005615 (EC: IDA, PMID: 19996109); GO_0006810 (EC: TAS, PMID: 12617161); GO_0007584 (EC: IEA); GO_0007596 (EC: TAS); GO_0008144 (EC: IDA, PMID: 16169013); GO_0008144 (EC: NAS, PMID: 10940303); GO_0008206 (EC: TAS); GO_0008270 (EC: IEA); GO_0009267 (EC: IDA, PMID: 16245148); GO_0010033 (EC: IEA); GO_0015643 (EC: IDA, PMID: 16169013); GO_0015721 (EC: TAS); GO_0016209 (EC: NAS, PMID: 14726550); GO_0019825 (EC: IDA, Qualifier: contributes_to, PMID: 16283771); GO_0019836 (EC: IDA, PMID: 16394536); GO_0019899 (EC: IEA); GO_0030168 (EC: TAS); GO_0030170 (EC: IDA, PMID: 16201370); GO_0031093 (EC: TAS); GO_0042157 (EC: TAS); GO_0043066 (EC: IDA, PMID: 16153637); GO_0043069 (EC: NAS, PMID: 14726550); GO_0043234 (EC: IDA, PMID: 16283771); GO_0043252 (EC: TAS); GO_0044281 (EC: TAS); GO_0046010 (EC: IEA); GO_0046689 (EC: IEA); GO_0051087 (EC: IPI, PMID: 19996109); GO_0051659 (EC: IDA, PMID: 16153637); GO_0055085 (EC: TAS); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070541 (EC: IEA); GO_0072562 (EC: IDA) PMID: 325004; 571335; 656055; 683332; 955075; 1225573; 1347703; 1390939; 1518850; 1602151; 1630489; 1810199; 1819460; 1859851; 1946412; 2068071; 2104980; 2247440; 2339130; 2374930; 2404284; 2419329; 2437111; 2460858; 2564675; 2727704; 2762316; 2792379; 2898383; 2901102; 2911589; 2914956; 3009475; 3081519; 3087352; 3353369; 3474609; 3479777; 3759977; 3795040; 3828358; 4027254; 4062880; 6171778; 6173750; 6192711; 6275391; 6292049; 6324579; 6457647; 6864486; 6933567; 7297678; 7557095; 7576927; 7578225; 7852505; 7882997; 7895732; 7902134; 8022807; 8048949; 8063017; 8064810; 8132774; 8134387; 8312056; 8347685; 8513793; 8605586; 8889549; 8898021; 9168236; 9183005; 9329347; 9589637; 9618718; 9731778; 10086322; 10388840; 10580404; 10780709; 10811843; 10940303; 11140838; 11145723; 11158855; 11159893; 11168369; 11483580; 11680902; 11689002; 11734007; 11743520; 11743713; 11781148; 11810025; 11847277; 11906609; 11931649; 12007569; 12009306; 12118010; 12477932; 12480711; 12566415; 12601813; 12617161; 12665801; 12732844; 12815038; 12969171; 12970360; 12975309; 13677478; 14520007; 14579113; 14687905; 14718574; 14726550; 14759223; 14983239; 15137089; 15149953; 15174051; 15210122; 15324660; 15353599; 15489334; 15502818; 15604093; 15616580; 15646839; 15716124; 15740590; 15832324; 15837789; 15890566; 15913893; 15942949; 15952740; 15996651; 16037246; 16054887; 16099937; 16153637; 16156788; 16159939; 16169013; 16169070; 16201370; 16213467; 16245148; 16253963; 16283771; 16289007; 16307046; 16324740; 16329499; 16337614; 16344560; 16394536; 16405401; 16413734; 16413740; 16413837; 16454580; 16608438; 16703327; 16705651; 16721655; 16843720; 16892178; 16916777; 16939204; 16979183; 17002873; 17048273; 17048876; 17054386; 17058928; 17064838; 17067818; 17109502; 17184834; 17200780; 17301560; 17347578; 17438360; 17460892; 17467280; 17499233; 17575979; 17587712; 17603933; 17940721; 17987802; 18028874; 18029235; 18054940; 18068661; 18178096; 18192916; 18200582; 18200583; 18256067; 18287254; 18323672; 18337751; 18346470; 18386863; 18459107; 18464274; 18474236; 18513410; 18579803; 18791744; 18958405; 18979581; 19011736; 19056867; 19139584; 19212124; 19298387; 19318029; 19339807; 19375269; 19377253; 19404566; 19450464; 19484197; 19505594; 19520864; 19572666; 19588173; 19601929; 19615354; 19615732; 19664386; 19707690; 19711930; 19733855; 19734142; 19785033; 19883602; 19884191; 19955769; 19996109; 20006594; 20018394; 20018855; 20025859; 20160662; 20171595; 20211614; 20215742; 20306030; 20346571; 20381621; 20471030; 20473970; 20603593; 20692819; 20705604; 20716240; 20818804; 20828817; 20835227; 21139048; 21190025; 21190670; 21193536; 21228463; 21271345; 21326965; 21357544; 21439346; 21456469; 21488149; 21494773; 21521316; 21539799; 21565611; 21635915; 21832049; 21843484; 21890473; 21900206; 21950461; 21997768; 22079093; 22120732; 22209935; 22244477; 22286219; 22306656; 22351593; 22437883; 22440250; 22450170; 22513409; 22549788; 22613267; 22630368; 22642562; 22675238; 22685563; 22718756; 22797925; 22815976; 22832880; 22870899; 22878801; 22905377; 22968245; 22982313; 23099538; 23103397; 23104623; 23176518; 23182422; 23215783; 23285146; 23351092; 23360066; 23398456; 23455922; 23473402; 23531836; 23535732; 23538348; 23592780; 23673386; 23724004; 23732484; 23862649; 23888317; 23958299; 24076337; 24244333; 24627724 albumin Ensembl:ENSG00000163631 HGNC:399 HPRD:00062 MIM:103600 Vega:OTTHUMG00000129919 ALB Bin Zhao, Yue Liu, Oliver He ALDH-E2 ALDHI ALDM WEB: http://www.ncbi.nlm.nih.gov/gene ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 217 12q24.2 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0004029 (EC: EXP); GO_0004030 (EC: TAS, PMID: 8903321); GO_0005759 (EC: TAS); GO_0005975 (EC: TAS, PMID: 8903321); GO_0006066 (EC: TAS, PMID: 1306115); GO_0006068 (EC: IEA); GO_0006069 (EC: TAS); GO_0006805 (EC: TAS); GO_0007268 (EC: TAS); GO_0009055 (EC: TAS, PMID: 8903321); GO_0042136 (EC: TAS); GO_0044281 (EC: TAS); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1306115; 2562960; 2838413; 2987944; 3017845; 3562250; 3582651; 3610592; 3653404; 4015823; 4065146; 6582480; 7593603; 8125298; 8290656; 8561277; 8889548; 8903321; 9195888; 9309300; 9765594; 10631996; 11051375; 11115843; 11117576; 11210104; 11238183; 11375898; 11410735; 11410744; 11468345; 11510748; 11520401; 11584144; 11600186; 11692094; 11696658; 11744614; 11748356; 11767261; 11798074; 11925062; 11966948; 12010862; 12033531; 12080432; 12082496; 12089173; 12119207; 12164325; 12168074; 12170102; 12173598; 12189549; 12198368; 12198369; 12211622; 12213289; 12223435; 12351924; 12376487; 12387818; 12419833; 12452318; 12477932; 12484509; 12492137; 12505800; 12517056; 12519453; 12545748; 12554615; 12563175; 12705718; 12706323; 12706324; 12718576; 12718671; 12739102; 12759156; 12759747; 12766630; 12777946; 12795606; 12798968; 12806963; 12824748; 12884000; 12915514; 12915519; 12940444; 14506399; 14506613; 14568296; 14597338; 14634838; 14636437; 14652286; 14691372; 14693654; 14742656; 14768474; 15008789; 15084894; 15122947; 15123334; 15126281; 15167446; 15182962; 15220553; 15242332; 15279067; 15318096; 15318097; 15318112; 15327835; 15377279; 15489334; 15511718; 15519646; 15542751; 15563966; 15569633; 15654505; 15679538; 15703303; 15714130; 15734972; 15780035; 15840430; 15842823; 15863807; 15902904; 15957669; 15957670; 15983043; 15991278; 16006997; 16046871; 16078602; 16082583; 16103445; 16108833; 16125912; 16126235; 16127737; 16135443; 16163053; 16169070; 16187278; 16235983; 16250071; 16309369; 16324524; 16332725; 16351505; 16365683; 16385179; 16404797; 16408483; 16440063; 16440362; 16499490; 16520888; 16565959; 16600530; 16608143; 16624836; 16639733; 16679343; 16679777; 16685648; 16702384; 16734278; 16758956; 16759795; 16782756; 16788276; 16792555; 16822169; 16847426; 16958672; 17033202; 17036331; 17040107; 17071628; 17134659; 17138329; 17196743; 17207821; 17285601; 17292341; 17384900; 17388993; 17454860; 17459359; 17471563; 17489985; 17517051; 17543846; 17559142; 17631643; 17632320; 17659824; 17785925; 17850643; 17854793; 17885622; 17948892; 17952709; 17963305; 17984618; 18033686; 18056758; 18078815; 18201725; 18215653; 18216179; 18254707; 18258609; 18272654; 18299763; 18302046; 18317873; 18318597; 18322963; 18331377; 18336671; 18429959; 18439068; 18450747; 18510611; 18516948; 18540919; 18616675; 18621017; 18665932; 18676680; 18715275; 18724972; 18763293; 18772068; 18773092; 18776700; 18782342; 18786921; 18787502; 18798003; 18974607; 18996923; 19056867; 19064571; 19068087; 19096130; 19115622; 19124505; 19144977; 19164089; 19170196; 19182438; 19185835; 19230487; 19250143; 19251454; 19261511; 19262484; 19286920; 19298323; 19298328; 19302089; 19332462; 19336370; 19339270; 19343046; 19393179; 19403456; 19449376; 19452585; 19456322; 19469618; 19486361; 19506075; 19584771; 19618839; 19625176; 19637400; 19641380; 19655364; 19667493; 19692168; 19698717; 19706845; 19751749; 19769429; 19799139; 19819294; 19826048; 19860798; 19861527; 19874574; 19876063; 19906643; 19911129; 19913121; 19914339; 19948975; 20005475; 20010786; 20025435; 20042735; 20062057; 20077761; 20093384; 20100738; 20101753; 20139978; 20180013; 20180859; 20186120; 20205700; 20364586; 20381070; 20403997; 20417517; 20437850; 20467232; 20477767; 20477771; 20488846; 20518787; 20521872; 20541757; 20562859; 20577142; 20590827; 20598484; 20628086; 20632450; 20652463; 20685249; 20700531; 20731752; 20806441; 20833657; 20877124; 20877624; 21039630; 21070510; 21085683; 21114754; 21133627; 21139048; 21145461; 21157980; 21252222; 21270382; 21309949; 21321583; 21355870; 21372407; 21437268; 21476199; 21507992; 21515512; 21536753; 21572416; 21576033; 21601984; 21664374; 21672255; 21723677; 21820149; 21832049; 21848961; 21861333; 21906983; 21917409; 21946912; 21958412; 21971053; 21988832; 22004425; 22102315; 22144473; 22155604; 22155639; 22171074; 22180476; 22231434; 22279680; 22286173; 22287615; 22292652; 22302076; 22455355; 22507973; 22508505; 22551939; 22563891; 22564712; 22591209; 22703580; 22708399; 22797727; 22839215; 22870576; 22879089; 22909898; 22930414; 22931071; 22954124; 22960999; 22988236; 23041239; 23106910; 23111423; 23149980; 23238616; 23247008; 23266708; 23295226; 23296215; 23303836; 23323620; 23354068; 23364009; 23364394; 23447675; 23454351; 23455379; 23525499; 23550892; 23609397; 23615284; 23667679; 23685282; 23685324; 23697560; 23986996; 24037726; 24382882 aldehyde dehydrogenase 2 family (mitochondrial) Ensembl:ENSG00000111275 HGNC:404 HPRD:00003 MIM:100650 Vega:OTTHUMG00000169603 ALDH2 Bin Zhao, Yue Liu, Oliver He 5-LO 5-LOX 5LPG LOG5 WEB: http://www.ncbi.nlm.nih.gov/gene ALOX5 arachidonate 5-lipoxygenase 240 RP11-67C2.3 10q11.2 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0002540 (EC: IEA); GO_0004051 (EC: IDA); GO_0005506 (EC: IDA); GO_0005515 (EC: IPI, PMID: 11297527); GO_0005615 (EC: IDA); GO_0005635 (EC: IDA, PMID: 19233132); GO_0005635 (EC: TAS); GO_0005641 (EC: IDA, PMID: 8245774); GO_0005829 (EC: IDA, PMID: 19233132); GO_0005829 (EC: TAS); GO_0006691 (EC: TAS); GO_0016363 (EC: IDA, PMID: 19233132); GO_0019369 (EC: TAS); GO_0019370 (EC: IDA); GO_0019372 (EC: TAS); GO_0031965 (EC: IDA, PMID: 8245774); GO_0044281 (EC: TAS); GO_2001300 (EC: TAS) PMID: 1540191; 1939225; 2251250; 2565035; 2829172; 3134355; 3422434; 7556168; 7624354; 7929073; 8066098; 8125298; 8245774; 8268460; 8585605; 9079648; 9150468; 9435249; 9445303; 9639560; 10051563; 10514459; 10673219; 10779545; 11297527; 11462800; 11471199; 11785969; 11796736; 11844797; 12021253; 12107604; 12111389; 12140292; 12163367; 12234060; 12354292; 12477932; 12525578; 12629151; 12664574; 12695552; 12730086; 12751728; 12751768; 12751769; 12859962; 12893830; 12907138; 12911785; 14532840; 14702425; 14749922; 14767568; 15010818; 15219851; 15280375; 15301234; 15308583; 15616590; 15661803; 15848143; 15923196; 15933245; 16135563; 16165096; 16275640; 16293801; 16361798; 16364163; 16385451; 16402861; 16413224; 16495221; 16531984; 16537708; 16672272; 16698924; 16733792; 16750418; 16899822; 16919603; 16924104; 17018618; 17072961; 17080223; 17115186; 17236225; 17373700; 17373938; 17434678; 17460547; 17467166; 17500032; 17521309; 17616938; 17703412; 17825794; 17894944; 17909879; 17924829; 18174194; 18179798; 18180307; 18204779; 18218859; 18280718; 18295198; 18339529; 18366797; 18369664; 18398223; 18421027; 18421434; 18525291; 18571838; 18676680; 18678882; 18842779; 18843019; 18927292; 18976020; 18978352; 18991687; 18992148; 18996667; 19022417; 19053751; 19075240; 19083497; 19130089; 19131661; 19134178; 19170196; 19214143; 19224689; 19233132; 19247692; 19258923; 19390118; 19423540; 19446447; 19450127; 19473080; 19497113; 19524426; 19578796; 19625176; 19692168; 19717473; 19724895; 19807693; 19851296; 19888660; 19913121; 19919819; 19948975; 20110601; 20126469; 20128419; 20139978; 20173757; 20198315; 20372792; 20382140; 20388081; 20406964; 20438785; 20453000; 20503287; 20549218; 20592751; 20628086; 20677014; 20682687; 21098726; 21200133; 21224059; 21233389; 21296957; 21314617; 21403093; 21482803; 21540635; 21605700; 21723968; 21729626; 21832049; 21883892; 22050225; 22253131; 22282663; 22293202; 22363630; 22433003; 22516296; 22616993; 22690932; 22739369; 22808264; 22825379; 23067353; 23079278; 23079635; 23179791; 23332172; 23351835; 23448388; 23485709; 23600541; 23642263; 23746795; 23752617; 24130502 arachidonate 5-lipoxygenase Ensembl:ENSG00000012779 HGNC:435 HPRD:01065 MIM:152390 Vega:OTTHUMG00000018081 ALOX5 Bin Zhao, Yue Liu, Oliver He AMPH2 AMPHL SH3P9 WEB: http://www.ncbi.nlm.nih.gov/gene BIN1 bridging integrator 1 274 2q14 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 10903846); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA); GO_0006897 (EC: IEA); GO_0008021 (EC: IEA); GO_0008283 (EC: TAS, PMID: 8782822); GO_0010468 (EC: IMP, PMID: 10412034); GO_0012502 (EC: IMP, PMID: 10412034); GO_0015629 (EC: TAS, PMID: 9182667); GO_0016032 (EC: IEA); GO_0030424 (EC: IDA); GO_0032403 (EC: IEA); GO_0042692 (EC: IEA); GO_0042802 (EC: IPI); GO_0043196 (EC: IEA); GO_0043547 (EC: IEA); GO_0043679 (EC: IEA); GO_0044300 (EC: IEA); GO_0045664 (EC: IMP, PMID: 10412034); GO_0045807 (EC: IEA); GO_0046982 (EC: IEA); GO_0048156 (EC: IPI); GO_0048708 (EC: IMP, PMID: 10412034); GO_0051020 (EC: IEA); GO_0060987 (EC: IMP, PMID: 19004523); GO_0060988 (EC: IMP, PMID: 19004523); GO_0071156 (EC: IC, PMID: 10412034) PMID: 8619474; 8725406; 8782822; 8889548; 9110174; 9182529; 9182667; 9195986; 9223448; 9280305; 9315708; 9341169; 9348539; 9356459; 9395479; 9418903; 9603201; 9736607; 10036185; 10094488; 10380878; 10391921; 10412034; 10430869; 10449755; 10652430; 10738240; 10764771; 10899172; 10903846; 11032017; 11076863; 11230166; 11256614; 11306501; 11384986; 11422041; 11709703; 12183633; 12456676; 12477932; 12532338; 12558988; 12604805; 12668730; 12773571; 12972505; 14702039; 14704274; 15207703; 15302935; 15483625; 15489336; 15992821; 16115810; 16169070; 16275660; 16381901; 16516635; 16530520; 17059209; 17081983; 17210688; 17218774; 17474147; 17611416; 17671430; 17676042; 17699764; 18029348; 18154705; 18348166; 18658220; 18817572; 18985028; 19004523; 19144635; 19322201; 19418541; 19629135; 19851296; 19915558; 20140253; 20142620; 20169111; 20198315; 20211142; 20460622; 20558387; 20927630; 21059989; 21129173; 21220176; 21321396; 21347408; 21379329; 21390209; 21447796; 21460840; 21460841; 21623381; 21627779; 21678469; 21832049; 21984944; 22005930; 22281836; 22539578; 22544318; 22810585; 22832961; 22863883; 22976291; 23202439; 23570733; 23754947 bridging integrator 1 Ensembl:ENSG00000136717 HGNC:1052 HPRD:03150 MIM:601248 Vega:OTTHUMG00000131465 BIN1 Bin Zhao, Yue Liu, Oliver He APAF-1 CED4 WEB: http://www.ncbi.nlm.nih.gov/gene APAF1 apoptotic peptidase activating factor 1 317 12q23 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000166 (EC: TAS, PMID: 10383829); GO_0001843 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10206961); GO_0005524 (EC: IEA); GO_0005634 (EC: IEA); GO_0005829 (EC: TAS); GO_0006309 (EC: IEA); GO_0006915 (EC: TAS); GO_0006919 (EC: IDA); GO_0006952 (EC: IEA); GO_0007399 (EC: TAS, PMID: 9753320); GO_0008635 (EC: IDA, PMID: 9267021); GO_0008635 (EC: TAS); GO_0008656 (EC: NAS, PMID: 15009102); GO_0030900 (EC: IEA); GO_0042802 (EC: IEA); GO_0042981 (EC: TAS, PMID: 10441496); GO_0043065 (EC: TAS, PMID: 18309324); GO_0043293 (EC: IDA); GO_0043293 (EC: TAS, PMID: 18309324); GO_0043531 (EC: IEA); GO_0051402 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0072432 (EC: TAS, PMID: 18309324); GO_0097193 (EC: TAS, PMID: 18309324); GO_2001235 (EC: IEA) PMID: 9267021; 9390557; 9455477; 9488720; 9539746; 9651578; 9753320; 9829980; 9837928; 9878060; 9922454; 10206961; 10322433; 10364241; 10376594; 10383829; 10393175; 10441496; 10486928; 10543941; 10578182; 10702682; 10722681; 10764728; 10934467; 10949025; 11113115; 11230124; 11242052; 11389439; 11457460; 11550094; 11864614; 12021264; 12147322; 12149244; 12168954; 12477932; 12549820; 12615903; 12637514; 12804598; 12963020; 14566819; 14747474; 14993223; 15001356; 15009102; 15026369; 15033720; 15103018; 15262985; 15305193; 15378005; 15590702; 15649154; 15692060; 15703181; 15735003; 15829969; 15832174; 15832175; 15863166; 15972851; 16046141; 16098052; 16231040; 16232302; 16331630; 16420245; 16595687; 16951219; 16979168; 17081983; 17133271; 17274640; 17348858; 17361096; 17418785; 17534194; 17541304; 17603079; 17876870; 17882496; 17885667; 18029348; 18042457; 18093951; 18309324; 18373966; 18439902; 18587251; 18676680; 18719738; 18834886; 19056867; 19058789; 19074885; 19141860; 19170196; 19238172; 19322201; 19455599; 19603830; 19625176; 19662370; 19675677; 19692168; 19698783; 19801675; 19809088; 19913121; 20345447; 20379614; 20453000; 20628086; 20959405; 20977544; 21104989; 21139048; 21297999; 21528061; 21659556; 21890473; 21906983; 21922274; 22101335; 22143029; 22246185; 22335196; 22632162; 22996741; 23085065; 23207240; 23326121; 23521171; 23822711 apoptotic peptidase activating factor 1 Ensembl:ENSG00000120868 HGNC:576 HPRD:03755 MIM:602233 Vega:OTTHUMG00000170214 APAF1 Bin Zhao, Yue Liu, Oliver He D9S411E LIN10 MINT1 X11 X11A X11ALPHA WEB: http://www.ncbi.nlm.nih.gov/gene APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 320 9q13-q21.1 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0001540 (EC: IEA); GO_0001701 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11083918); GO_0005546 (EC: IEA); GO_0005634 (EC: IEA); GO_0005794 (EC: IEA); GO_0005886 (EC: IEA); GO_0006461 (EC: TAS, PMID: 9614075); GO_0006886 (EC: IEA); GO_0007155 (EC: TAS, PMID: 9753324); GO_0007268 (EC: IEA); GO_0007399 (EC: TAS, PMID: 9753324); GO_0007626 (EC: IEA); GO_0008021 (EC: TAS, PMID: 9753324); GO_0008088 (EC: TAS, PMID: 9822620); GO_0010468 (EC: IEA); GO_0014047 (EC: IEA); GO_0014051 (EC: IEA); GO_0030165 (EC: IEA); GO_0032403 (EC: IEA); GO_0035264 (EC: IEA); GO_0043234 (EC: IEA); GO_0048471 (EC: IEA) PMID: 1968060; 7545337; 7678331; 7719031; 8887653; 9321393; 9395480; 9585438; 9614075; 9753324; 9822620; 9952408; 10455105; 11010978; 11036064; 11083918; 11115513; 12006486; 12016213; 12093160; 12177192; 12196555; 12514209; 12849748; 12970358; 14756819; 14960569; 14970211; 15024025; 15164053; 15563604; 15699037; 16344560; 16413130; 18836734; 19720620; 20016085; 20160714; 20379614; 20468060; 20531236; 21178287; 21763699; 22355143; 23737971 amyloid beta (A4) precursor protein-binding, family A, member 1 Ensembl:ENSG00000107282 HGNC:578 HPRD:03879 MIM:602414 Vega:OTTHUMG00000019984 APBA1 Bin Zhao, Yue Liu, Oliver He FE65 MGC:9072 RIR WEB: http://www.ncbi.nlm.nih.gov/gene APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 322 11p15 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0001540 (EC: IPI, PMID: 18468999); GO_0001540 (EC: NAS, PMID: 8894693); GO_0001764 (EC: IEA); GO_0003682 (EC: IDA, PMID: 19343227); GO_0005515 (EC: IPI, PMID: 12972431); GO_0005634 (EC: IDA, PMID: 18468999); GO_0005634 (EC: ISS); GO_0005737 (EC: IDA, PMID: 18468999); GO_0005886 (EC: IDA); GO_0006302 (EC: IEA); GO_0006351 (EC: IEA); GO_0006355 (EC: ISS); GO_0006915 (EC: IEA); GO_0006974 (EC: IDA, PMID: 18468999); GO_0007050 (EC: ISS); GO_0007165 (EC: NAS, PMID: 8894693); GO_0007409 (EC: NAS, PMID: 12843239); GO_0007411 (EC: IEA); GO_0008134 (EC: ISS); GO_0008542 (EC: IEA); GO_0016607 (EC: IEA); GO_0030027 (EC: IDA, PMID: 12843239); GO_0030198 (EC: IEA); GO_0030308 (EC: ISS); GO_0030426 (EC: IDA, PMID: 12843239); GO_0042393 (EC: IPI, PMID: 19234442); GO_0043065 (EC: IDA, PMID: 18468999); GO_0043967 (EC: ISS); GO_0045202 (EC: IDA, PMID: 12843239); GO_0045665 (EC: IEA); GO_0045739 (EC: IEA); GO_0045893 (EC: IDA, PMID: 19343227); GO_0045944 (EC: IEA); GO_0050760 (EC: ISS); GO_0070064 (EC: IPI, PMID: 17686488) PMID: 8855266; 8887653; 8894693; 8955346; 9045663; 9407065; 9461550; 9585438; 9685356; 9738440; 9799084; 9837937; 10075692; 10081969; 10561691; 10945997; 11029529; 11065130; 11085987; 11095528; 11099823; 11115513; 11279131; 11436125; 11441186; 11517249; 11606623; 11741599; 11854179; 12089154; 12150997; 12477932; 12653567; 12727304; 12779321; 12843239; 12888553; 12972431; 14569203; 14572442; 14699153; 15037614; 15044485; 15146195; 15331662; 15489334; 15592452; 15647266; 15816856; 16049941; 16055720; 16223726; 16273093; 16332686; 16713569; 17332754; 17368826; 17512906; 17590240; 17686488; 17854420; 17855370; 18096514; 18468999; 18480379; 18550529; 18777128; 18800165; 18833287; 18922798; 19234442; 19343227; 19381069; 19913121; 20091743; 20133016; 20205790; 20405578; 20568118; 20628086; 21139048; 21145461; 21650223; 21824145; 21890473; 21900206; 21968187; 22199353; 22902274; 23000965; 23572515; 24056087 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Ensembl:ENSG00000166313 HGNC:581 HPRD:04087 MIM:602709 Vega:OTTHUMG00000165454 APBB1 Bin Zhao, Yue Liu, Oliver He BTPS2 DP2 DP2.5 DP3 GS PPP1R46 WEB: http://www.ncbi.nlm.nih.gov/gene APC adenomatous polyposis coli 324 5q21-q22 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0000281 (EC: IMP, PMID: 17570218); GO_0000776 (EC: IDA, PMID: 11283619); GO_0001822 (EC: IEA); GO_0001942 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10656683); GO_0005634 (EC: IDA, PMID: 11035805); GO_0005737 (EC: IDA, PMID: 11035805); GO_0005813 (EC: IDA, PMID: 11283619); GO_0005829 (EC: TAS); GO_0005881 (EC: IEA); GO_0005886 (EC: IDA); GO_0005886 (EC: IDA, Qualifier: colocalizes_with, PMID: 16611247); GO_0005913 (EC: IDA, Qualifier: colocalizes_with, PMID: 16611247); GO_0005923 (EC: IDA, PMID: 18502210); GO_0006461 (EC: IDA, PMID: 16188939); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0006974 (EC: IDA, PMID: 14728717); GO_0007026 (EC: IDA, PMID: 11166179); GO_0007026 (EC: IMP, PMID: 17192415); GO_0007050 (EC: IDA, PMID: 8521819); GO_0007091 (EC: IEA); GO_0007094 (EC: IMP, PMID: 17227893); GO_0007155 (EC: NAS, PMID: 8259518); GO_0007409 (EC: IEA); GO_0008013 (EC: IPI, PMID: 10773885); GO_0008017 (EC: IDA, PMID: 11166179); GO_0008285 (EC: IDA, PMID: 8521819); GO_0009798 (EC: IEA); GO_0009952 (EC: IEA); GO_0009953 (EC: IEA); GO_0009954 (EC: IEA); GO_0016328 (EC: IDA, PMID: 12072559); GO_0016477 (EC: IMP, PMID: 19151759); GO_0019887 (EC: IDA, PMID: 11972058); GO_0019901 (EC: IPI, PMID: 8638126); GO_0030027 (EC: IDA, PMID: 19151759); GO_0030335 (EC: IMP, PMID: 17192415); GO_0030858 (EC: IEA); GO_0030877 (EC: IDA, PMID: 16188939); GO_0031116 (EC: IEA); GO_0031122 (EC: IEA); GO_0031274 (EC: IMP, PMID: 17192415); GO_0032587 (EC: IDA, PMID: 19151759); GO_0032886 (EC: IMP); GO_0033077 (EC: IEA); GO_0035019 (EC: IEA); GO_0035371 (EC: IEA); GO_0042483 (EC: IEA); GO_0043065 (EC: IMP, PMID: 17227893); GO_0043409 (EC: IEA); GO_0044295 (EC: IEA); GO_0044336 (EC: IEA); GO_0044337 (EC: IEA); GO_0045295 (EC: IPI, PMID: 7890674); GO_0045296 (EC: IDA, Qualifier: NOT, PMID: 7890674); GO_0045667 (EC: IEA); GO_0045670 (EC: IEA); GO_0045732 (EC: IC, PMID: 16188939); GO_0045732 (EC: IGI, PMID: 12952940); GO_0045736 (EC: IDA, PMID: 8521819); GO_0045785 (EC: IEA); GO_0046716 (EC: IEA); GO_0048538 (EC: IEA); GO_0051010 (EC: IDA, PMID: 19632184); GO_0051171 (EC: IEA); GO_0051276 (EC: IEA); GO_0051781 (EC: IEA); GO_0051988 (EC: IMP, PMID: 17227893); GO_0051988 (EC: NAS, PMID: 11283619); GO_0060041 (EC: IEA); GO_0060070 (EC: IC, PMID: 9601641); GO_0060070 (EC: NAS, PMID: 11035805); GO_0060770 (EC: IEA); GO_0070830 (EC: NAS, PMID: 18502210); GO_0090090 (EC: IGI, PMID: 12952940) PMID: 1310068; 1338691; 1338764; 1338904; 1651562; 1651563; 1678319; 2797819; 3789010; 7606712; 7651399; 7661930; 7744883; 7833149; 7833931; 7890674; 8074697; 8111410; 8252630; 8259518; 8259519; 8383094; 8389242; 8521819; 8619474; 8638125; 8638126; 8889548; 8940264; 8990002; 9110174; 9188857; 9286858; 9298899; 9326658; 9375853; 9419979; 9482734; 9601641; 9637688; 9660858; 9707618; 9724771; 9731522; 9731533; 9734785; 9811605; 9950360; 9973276; 10074433; 10092233; 10188731; 10228155; 10330181; 10330403; 10426194; 10470088; 10545404; 10656683; 10666372; 10698523; 10749862; 10773885; 10782927; 10811618; 10926498; 10947987; 10951583; 10966653; 10982189; 11029657; 11035805; 11050185; 11076863; 11129339; 11136974; 11157977; 11159880; 11166179; 11221825; 11241320; 11241666; 11251183; 11283619; 11297546; 11348595; 11354631; 11389840; 11409872; 11466700; 11470413; 11483640; 11487538; 11487578; 11533658; 11535846; 11584047; 11585828; 11606402; 11668620; 11696170; 11707392; 11712088; 11720476; 11741105; 11748858; 11751382; 11754114; 11768389; 11768390; 11809680; 11809682; 11856748; 11868006; 11891193; 11912492; 11920497; 11921277; 11933206; 11943150; 11955436; 11956815; 11972058; 12000790; 12034871; 12045208; 12057910; 12070164; 12072559; 12093899; 12124804; 12136240; 12163385; 12173026; 12173321; 12374230; 12378616; 12387883; 12388762; 12439748; 12477932; 12485844; 12504226; 12508668; 12537656; 12538344; 12575848; 12581900; 12584179; 12606575; 12628243; 12647217; 12655564; 12737446; 12800081; 12800196; 12820959; 12856637; 12901799; 12907646; 12952940; 12955080; 14514668; 14520463; 14573780; 14574158; 14578136; 14578138; 14579148; 14624392; 14662741; 14672538; 14679305; 14691304; 14728717; 14729851; 14871261; 14961559; 14991743; 15020226; 15040027; 15108288; 15122587; 15123239; 15133491; 15161933; 15190067; 15251938; 15257316; 15266213; 15273719; 15294866; 15326380; 15327768; 15327769; 15331612; 15342556; 15355978; 15375803; 15446460; 15459959; 15507235; 15520370; 15523694; 15525529; 15540296; 15542524; 15548520; 15561772; 15572129; 15591320; 15639864; 15640937; 15689459; 15733272; 15754020; 15755874; 15761860; 15768050; 15778465; 15821699; 15824157; 15832580; 15833136; 15929773; 15943410; 15951963; 15952110; 15959913; 15981102; 16007220; 16030254; 16088911; 16142311; 16163548; 16184469; 16188939; 16196087; 16199882; 16201232; 16212417; 16228836; 16293619; 16322291; 16329837; 16344560; 16356174; 16382042; 16407829; 16411234; 16423286; 16426911; 16433700; 16450383; 16461775; 16510874; 16510875; 16525027; 16537703; 16545110; 16569251; 16611247; 16619216; 16650078; 16680592; 16699180; 16699861; 16710723; 16753179; 16763565; 16798748; 16804979; 16820884; 16843107; 16855398; 16951153; 16964243; 16981189; 17028196; 17039269; 17080006; 17081983; 17110338; 17116713; 17119068; 17126424; 17135276; 17143298; 17143620; 17176113; 17189293; 17192415; 17218255; 17221838; 17222366; 17227893; 17252231; 17255093; 17297457; 17360132; 17368237; 17410430; 17411426; 17418091; 17437043; 17454753; 17486639; 17489848; 17505512; 17506007; 17556698; 17558858; 17562260; 17562262; 17569124; 17570218; 17572842; 17588722; 17620292; 17653897; 17665205; 17704924; 17854661; 17882487; 17905526; 17910481; 17920230; 17927853; 17947477; 17952864; 17954272; 17960617; 17963004; 17964080; 17968317; 17973119; 18026870; 18027849; 18058812; 18063416; 18066497; 18070451; 18091433; 18160396; 18166348; 18199528; 18224684; 18265644; 18281465; 18321998; 18337602; 18343606; 18369740; 18375958; 18384130; 18387968; 18393237; 18393246; 18403596; 18406876; 18418860; 18433509; 18451217; 18454178; 18474248; 18477604; 18483325; 18485586; 18486530; 18498351; 18502210; 18519734; 18612690; 18617334; 18629513; 18630182; 18632633; 18632657; 18632876; 18632987; 18646694; 18662704; 18662849; 18676680; 18708403; 18770064; 18774639; 18807072; 18841156; 18844223; 18847451; 18854359; 18955873; 18977219; 18982352; 18987576; 18992263; 18992635; 19013464; 19026650; 19029688; 19035518; 19036155; 19061640; 19064572; 19110823; 19111562; 19124205; 19151759; 19164452; 19169759; 19170196; 19196998; 19240029; 19261806; 19307944; 19309276; 19337631; 19351817; 19378335; 19426738; 19444466; 19448414; 19450512; 19453261; 19470943; 19474113; 19506903; 19515250; 19525225; 19527492; 19527921; 19531215; 19543899; 19571702; 19576224; 19584833; 19593690; 19606680; 19615284; 19615732; 19617769; 19625176; 19632184; 19654215; 19672874; 19679059; 19692168; 19694001; 19701947; 19703905; 19728755; 19768578; 19773381; 19777185; 19793053; 19845967; 19888426; 19889076; 19900189; 19900451; 19912361; 19913121; 19928347; 19928349; 19928352; 19928354; 19945765; 19966865; 20007843; 20027139; 20033212; 20056645; 20063100; 20092957; 20128690; 20149637; 20208994; 20229069; 20237496; 20301519; 20333795; 20352275; 20360068; 20371677; 20434453; 20437058; 20453000; 20473645; 20510605; 20513532; 20519433; 20544848; 20564245; 20570909; 20613673; 20628086; 20649969; 20658693; 20685668; 20696638; 20696710; 20696900; 20723290; 20800603; 20840677; 20844082; 20844743; 20850014; 20887112; 20924072; 20935450; 20936779; 20971552; 20978149; 20978327; 21057000; 21078161; 21110124; 21139048; 21199875; 21207416; 21225915; 21279955; 21302450; 21309064; 21311754; 21315632; 21359685; 21404461; 21442240; 21484796; 21538028; 21573497; 21598003; 21643010; 21664290; 21665989; 21680534; 21737640; 21779980; 21788986; 21807601; 21857949; 21858148; 21859464; 21865138; 21871439; 21900494; 21901162; 21902576; 21904137; 21909382; 21915313; 21948542; 21949247; 21995949; 22000517; 22073196; 22077694; 22081130; 22103048; 22184111; 22262720; 22277732; 22294772; 22324744; 22372443; 22380946; 22431159; 22434720; 22469663; 22496417; 22509309; 22528324; 22669205; 22682247; 22704062; 22719865; 22740476; 22741528; 22761442; 22787431; 22795047; 22796397; 22825279; 22851115; 22864938; 22884971; 22886683; 22893084; 22898821; 22907428; 22976915; 22987206; 23011394; 23055343; 23085758; 23087084; 23131390; 23159080; 23159591; 23244118; 23277359; 23291410; 23299921; 23302090; 23326336; 23334997; 23382461; 23393221; 23405266; 23469016; 23504555; 23525311; 23555190; 23561487; 23602568; 23646120; 23788249; 23796566; 23840886; 23846443; 23871111; 23874531; 23896379; 24005794; 24139208; 24250222; 24255178 adenomatous polyposis coli Ensembl:ENSG00000134982 HGNC:583 HPRD:01439 MIM:611731 Vega:OTTHUMG00000128806 APC Bin Zhao, Yue Liu, Oliver He AARE ACPH APH D3F15S2 D3S48E DNF15S2 OPH WEB: http://www.ncbi.nlm.nih.gov/gene APEH acylaminoacyl-peptide hydrolase 327 3p21.31 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0004252 (EC: IDA, PMID: 17241160); GO_0005737 (EC: IDA); GO_0006508 (EC: IDA, PMID: 17241160); GO_0008242 (EC: IDA, PMID: 17241160); GO_0031965 (EC: IDA); GO_0044822 (EC: IDA); GO_0050435 (EC: IDA, PMID: 17241160); GO_0070062 (EC: IDA) PMID: 1521574; 1740429; 1861871; 2006156; 2392324; 2565880; 8411161; 8724851; 10395453; 10407158; 10719179; 11921441; 12000146; 12477932; 15489334; 15862967; 16169070; 16189514; 17241160; 18029348; 18781797; 20307617; 20529763; 21139048; 21297633; 21890473; 21906983; 21931648; 21963094; 21987572; 22505724; 22863883; 22939629; 23000965 acylaminoacyl-peptide hydrolase Ensembl:ENSG00000164062 HGNC:586 HPRD:00034 MIM:102645 Vega:OTTHUMG00000156882 APEH Bin Zhao, Yue Liu, Oliver He APE APE1 APEN APEX APX HAP1 REF1 WEB: http://www.ncbi.nlm.nih.gov/gene APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 328 14q11.2 20140408 9606 14 protein-coding Official from a nomenclature committee GO_0000737 (EC: IDA, PMID: 19188445); GO_0000737 (EC: TAS, PMID: 1722334); GO_0003677 (EC: IDA, PMID: 11286553); GO_0003684 (EC: IDA, PMID: 12524539); GO_0003713 (EC: IDA, PMID: 9119221); GO_0003714 (EC: TAS, PMID: 7961715); GO_0003906 (EC: IDA, PMID: 19188445); GO_0003906 (EC: TAS, PMID: 9119221); GO_0004519 (EC: IDA, PMID: 11478795); GO_0004520 (EC: TAS, PMID: 1722334); GO_0004523 (EC: TAS, PMID: 11286553); GO_0004528 (EC: TAS, PMID: 9119221); GO_0004844 (EC: TAS, PMID: 10805771); GO_0005515 (EC: IPI, PMID: 11118054); GO_0005634 (EC: IDA); GO_0005654 (EC: IDA, PMID: 17148573); GO_0005654 (EC: TAS); GO_0005667 (EC: IEA); GO_0005730 (EC: IDA, PMID: 17148573); GO_0005737 (EC: IDA, PMID: 9560228); GO_0005739 (EC: IDA); GO_0005783 (EC: TAS, PMID: 12524539); GO_0005813 (EC: IDA); GO_0005840 (EC: TAS, PMID: 12524539); GO_0006281 (EC: IDA, PMID: 9560228); GO_0006281 (EC: TAS); GO_0006284 (EC: TAS); GO_0006310 (EC: IEA); GO_0006351 (EC: IEA); GO_0006355 (EC: IEA); GO_0007568 (EC: IEA); GO_0008081 (EC: IDA, PMID: 11478795); GO_0008408 (EC: IDA, PMID: 11832948); GO_0008408 (EC: TAS, PMID: 11286553); GO_0014912 (EC: IEA); GO_0016491 (EC: IDA, PMID: 12524539); GO_0016607 (EC: IDA, PMID: 17148573); GO_0016890 (EC: IDA, PMID: 19188445); GO_0031490 (EC: IDA, PMID: 11809897); GO_0032403 (EC: IEA); GO_0042493 (EC: IEA); GO_0043488 (EC: IMP, PMID: 19401441); GO_0044822 (EC: IDA); GO_0045454 (EC: IEA); GO_0045739 (EC: IDA, PMID: 9207062); GO_0046872 (EC: IDA, PMID: 11286553); GO_0048471 (EC: IDA, PMID: 12524539); GO_0051059 (EC: IEA); GO_0055114 (EC: IDA, PMID: 12524539); GO_0070301 (EC: IEA); GO_0071320 (EC: IEA); GO_0071375 (EC: IEA); GO_0080111 (EC: IDA); GO_0090305 (EC: IDA, PMID: 11478795); GO_0090305 (EC: TAS, PMID: 11286553); GO_0090502 (EC: TAS, PMID: 11286553); GO_1900087 (EC: IEA) PMID: 1284593; 1371347; 1380454; 1380694; 1383925; 1627644; 1719477; 1722334; 7961715; 8086453; 8619474; 8621488; 8932375; 8942627; 9108029; 9110174; 9119221; 9207062; 9351835; 9361024; 9560228; 9870152; 10023679; 10559261; 10585464; 10594042; 10629618; 10667800; 10805771; 10946230; 11073998; 11084372; 11092888; 11096142; 11118054; 11133992; 11182545; 11250913; 11286553; 11452037; 11478795; 11601988; 11705870; 11707423; 11809897; 11832948; 11846302; 11866537; 11895912; 12058277; 12110916; 12161506; 12200445; 12230304; 12231548; 12237116; 12242029; 12384995; 12477932; 12480540; 12519758; 12524539; 12547389; 12555094; 12569263; 12624104; 12628186; 12842873; 12857737; 12860125; 12933815; 12966083; 14521941; 14581338; 14594818; 14599768; 14625810; 14630715; 14633989; 14643949; 14704345; 14730972; 14767913; 15044328; 15084314; 15107486; 15113441; 15210853; 15247342; 15316562; 15333465; 15362040; 15380100; 15459284; 15472121; 15489334; 15518571; 15592455; 15635413; 15644200; 15674341; 15694346; 15706084; 15731342; 15735682; 15746160; 15816625; 15824325; 15824742; 15831793; 15878096; 15887293; 15942031; 16000577; 16147991; 16195237; 16221808; 16284386; 16356936; 16406883; 16425270; 16481227; 16481390; 16492928; 16537925; 16554306; 16609022; 16621887; 16712791; 16844323; 16889694; 16956909; 16962936; 16966185; 16973282; 16978929; 16982113; 17008916; 17028303; 17034901; 17040931; 17126083; 17148573; 17177211; 17197435; 17203305; 17218168; 17222938; 17230526; 17272283; 17283177; 17324338; 17332344; 17355977; 17374727; 17403694; 17479230; 17515960; 17531525; 17555083; 17567600; 17567611; 17599408; 17614107; 17630376; 17685223; 17855454; 17898541; 17922186; 17938202; 17949784; 17974506; 17984110; 17991492; 18025089; 18029348; 18042731; 18053222; 18061304; 18091433; 18179823; 18206643; 18208837; 18263880; 18324520; 18353858; 18357393; 18393760; 18436236; 18439621; 18466396; 18478337; 18482781; 18503157; 18505345; 18515104; 18627000; 18627350; 18669164; 18672023; 18676680; 18701435; 18712175; 18776186; 18779313; 18781797; 18805789; 18809583; 18823566; 18830263; 18850631; 18946634; 18958420; 18971960; 18983843; 18990748; 19029194; 19038866; 19041121; 19052983; 19064572; 19073198; 19074850; 19097035; 19116388; 19124499; 19124501; 19147860; 19170196; 19181704; 19188437; 19188445; 19219073; 19237606; 19242824; 19292061; 19324449; 19339270; 19351502; 19367277; 19369898; 19376732; 19393248; 19401441; 19414392; 19449863; 19460860; 19470598; 19471022; 19484131; 19492297; 19505873; 19524065; 19528510; 19536092; 19541747; 19592152; 19625176; 19631633; 19643912; 19692168; 19711438; 19762350; 19764832; 19782121; 19787261; 19789190; 19846872; 19896490; 19902366; 19934257; 20010699; 20032196; 20061190; 20087352; 20133634; 20150366; 20211142; 20218738; 20218899; 20223788; 20226869; 20231292; 20232390; 20332233; 20354815; 20377204; 20391347; 20403997; 20453000; 20493910; 20496165; 20498636; 20522537; 20530453; 20534262; 20540786; 20574454; 20577654; 20601096; 20606276; 20633698; 20634891; 20644561; 20679741; 20696907; 20699270; 20720310; 20731661; 20808930; 20817763; 20852942; 20856196; 20919954; 20929586; 20955519; 21030352; 21037106; 21044950; 21110914; 21132382; 21139048; 21198260; 21323960; 21420246; 21429202; 21451252; 21467074; 21479902; 21538578; 21561390; 21615620; 21722819; 21727086; 21756546; 21769563; 21778470; 21832049; 21865600; 21900206; 21906983; 21912662; 21933813; 21935361; 21987080; 22024594; 22148505; 22174317; 22176746; 22193858; 22205985; 22224629; 22243137; 22306120; 22329793; 22362780; 22371940; 22379092; 22384055; 22493391; 22580151; 22652909; 22713458; 22863883; 22918947; 22939629; 23038158; 23065211; 23074184; 23094050; 23110144; 23143180; 23268706; 23272074; 23315699; 23355472; 23369758; 23382073; 23408843; 23418439; 23430444; 23479135; 23485469; 23505922; 23544830; 23581410; 23602568; 23643942; 23665318; 23669291; 23749940; 23776569; 23781133; 23871947; 23874636; 23898172; 23934858; 23994194; 24023291; 24076439; 24079850; 24127576; 24209961; 24284961 APEX nuclease (multifunctional DNA repair enzyme) 1 Ensembl:ENSG00000100823 HGNC:587 HPRD:00136 MIM:107748 Vega:OTTHUMG00000029544 APEX1 Bin Zhao, Yue Liu, Oliver He APLP WEB: http://www.ncbi.nlm.nih.gov/gene APLP1 amyloid beta (A4) precursor-like protein 1 333 19q13.1 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 16169070); GO_0005604 (EC: TAS, PMID: 9521588); GO_0005794 (EC: IEA); GO_0005886 (EC: IDA, PMID: 16531006); GO_0006378 (EC: IEA); GO_0006417 (EC: IEA); GO_0006897 (EC: IEA); GO_0006915 (EC: IEA); GO_0007155 (EC: IEA); GO_0007193 (EC: IC, PMID: 16531006); GO_0007399 (EC: TAS, PMID: 9521588); GO_0008201 (EC: IEA); GO_0009887 (EC: TAS, PMID: 9521588); GO_0016021 (EC: IEA); GO_0030198 (EC: IEA); GO_0030818 (EC: IDA, PMID: 16531006); GO_0030900 (EC: IEA); GO_0031694 (EC: IPI, PMID: 16531006); GO_0031695 (EC: IPI, PMID: 16531006); GO_0031696 (EC: IPI, PMID: 16531006); GO_0042802 (EC: IPI, PMID: 16193067); GO_0046914 (EC: IEA); GO_0048471 (EC: IDA, PMID: 16531006); GO_0071874 (EC: IDA, PMID: 16531006) PMID: 7494461; 7929392; 8432545; 8894693; 9428684; 9521588; 9729270; 9890987; 10081969; 10460257; 10578233; 11247302; 12135352; 12228233; 12477932; 12779321; 14563850; 14597230; 14699153; 14702039; 14970212; 14983046; 15146195; 15208260; 15383276; 15489334; 16169070; 16193067; 16344553; 16531006; 17620599; 17709753; 18272596; 18430897; 19126676; 19401174; 20049724; 21178287; 21574595; 21900206; 21952790; 22178872; 23864651; 23874953 amyloid beta (A4) precursor-like protein 1 Ensembl:ENSG00000105290 HGNC:597 HPRD:00102 MIM:104775 Vega:OTTHUMG00000180692 APLP1 Bin Zhao, Yue Liu, Oliver He APLP-2 APPH APPL2 CDEBP WEB: http://www.ncbi.nlm.nih.gov/gene APLP2 amyloid beta (A4) precursor-like protein 2 334 11q24 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0001967 (EC: IEA); GO_0003677 (EC: NAS, PMID: 7702756); GO_0004867 (EC: IEA); GO_0005515 (EC: IPI, PMID: 16193067); GO_0005634 (EC: IDA, PMID: 7702756); GO_0005886 (EC: IEA); GO_0006878 (EC: IEA); GO_0007176 (EC: IEA); GO_0007186 (EC: NAS, PMID: 8220435); GO_0007617 (EC: IEA); GO_0007626 (EC: IEA); GO_0008201 (EC: IEA); GO_0008203 (EC: IEA); GO_0009790 (EC: IEA); GO_0016021 (EC: NAS, PMID: 8485127); GO_0030198 (EC: IEA); GO_0030900 (EC: IEA); GO_0030901 (EC: IEA); GO_0042802 (EC: IPI, PMID: 16193067); GO_0043393 (EC: IEA); GO_0046914 (EC: IEA); GO_0050885 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19199708) PMID: 7539437; 7702756; 7929392; 8020984; 8125298; 8220435; 8485127; 8855266; 8894693; 9109675; 9461550; 9556595; 10081969; 10460257; 10490823; 10702673; 11247302; 11443060; 11746496; 12228233; 12372026; 12477932; 12499552; 12595709; 12917434; 14597230; 14699153; 14702039; 14970212; 14983046; 15146195; 15208260; 15231748; 15489334; 15584916; 15778465; 16193067; 16279945; 16622416; 16645641; 17371289; 17405931; 17452623; 17709753; 18452037; 18641335; 19019082; 19126676; 19184004; 19199708; 19322201; 19808674; 20195357; 20379614; 20732423; 20936779; 21081666; 21103663; 21139048; 21178287; 21459473; 21522131; 21695060; 21826533; 21875946; 21890473; 21906983; 21952790; 21963094; 21987572; 21988832; 22641691; 22797723; 23000965; 23430252 amyloid beta (A4) precursor-like protein 2 Ensembl:ENSG00000084234 HGNC:598 HPRD:00103 MIM:104776 Vega:OTTHUMG00000165767 APLP2 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene APOC1 apolipoprotein C-I 341 19q13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0004859 (EC: IDA, PMID: 2302419); GO_0005504 (EC: IDA, PMID: 17339654); GO_0005783 (EC: IDA); GO_0006629 (EC: TAS, PMID: 2897845); GO_0006641 (EC: IEA); GO_0008203 (EC: IEA); GO_0010873 (EC: TAS, PMID: 18992221); GO_0010900 (EC: IDA, PMID: 2302419); GO_0010916 (EC: IDA, PMID: 1917954); GO_0031210 (EC: TAS, PMID: 2302419); GO_0032374 (EC: IC, PMID: 15576844); GO_0032375 (EC: IDA, PMID: 10978346); GO_0033344 (EC: IDA, PMID: 11162594); GO_0033700 (EC: IDA, PMID: 11162594); GO_0034361 (EC: IDA, PMID: 15576844); GO_0034364 (EC: IDA, PMID: 15576844); GO_0034369 (EC: IDA, PMID: 10978346); GO_0034375 (EC: TAS, PMID: 18992221); GO_0034379 (EC: TAS, PMID: 18992221); GO_0034382 (EC: IDA, PMID: 4020294); GO_0034447 (EC: IGI, PMID: 15576844); GO_0042157 (EC: IEA); GO_0042627 (EC: TAS, PMID: 18992221); GO_0043085 (EC: TAS, PMID: 18992221); GO_0045717 (EC: IDA, PMID: 15576844); GO_0045833 (EC: IDA, PMID: 182536); GO_0048261 (EC: IDA, PMID: 1917954); GO_0050995 (EC: IDA, PMID: 15576844); GO_0051005 (EC: IDA, PMID: 15576844); GO_0055102 (EC: IDA, PMID: 15576844); GO_0060228 (EC: TAS, PMID: 18992221) PMID: 166984; 182536; 1917954; 2302419; 2835369; 2897845; 2985493; 3013172; 3017837; 4020294; 4369340; 6328444; 6789904; 7471419; 7779782; 8125298; 8432525; 8804993; 9300485; 10391210; 10520737; 10978346; 11054415; 11076863; 11162594; 11256614; 11702052; 11825674; 11991719; 12032151; 12044170; 12113906; 12220441; 12429068; 12477932; 12678662; 12705839; 12736801; 12805445; 12860251; 12962909; 14523051; 14705977; 14746139; 15077570; 15174051; 15339254; 15364690; 15489334; 15489336; 15576844; 15767578; 15769335; 15777558; 15793777; 15840864; 15900219; 16159884; 16381901; 16459141; 16478678; 16544732; 16608402; 16631424; 16763159; 16935938; 16981907; 17053273; 17254710; 17310220; 17339654; 17341095; 17463246; 17474819; 17667986; 17761674; 17936795; 17975299; 17998437; 18037960; 18049452; 18160739; 18193043; 18193044; 18262040; 18667498; 18802019; 18835943; 18976728; 18984910; 18992221; 19014618; 19060906; 19062221; 19197348; 19252179; 19336475; 19336575; 19368908; 19417222; 19494537; 19567438; 19761869; 19785722; 19808960; 19812053; 19913121; 19936222; 20145290; 20209111; 20308432; 20331378; 20339536; 20430392; 20442857; 20498921; 20571754; 20580041; 20628086; 20686565; 20691829; 20714348; 20864672; 20880607; 20972250; 21103663; 21187063; 21196492; 21267442; 21300955; 21533863; 21740922; 21900206; 21909108; 21943158; 22003152; 22005931; 22022282; 22054870; 22264166; 22286219; 22404376; 22474067; 22710912; 22832961; 22995522; 23031429; 23118302; 23419831; 23455636; 23555584; 23726366; 24023261; 24121499 apolipoprotein C-I APOC1 Bin Zhao, Yue Liu, Oliver He APO-CIV APOC-IV WEB: http://www.ncbi.nlm.nih.gov/gene APOC4 apolipoprotein C-IV 346 19q13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005319 (EC: TAS, PMID: 8530039); GO_0006629 (EC: TAS, PMID: 8530039); GO_0010890 (EC: IMP, PMID: 18809223); GO_0034361 (EC: IDA, PMID: 12700345); GO_0034361 (EC: IMP, PMID: 8827523); GO_0034364 (EC: IDA, PMID: 12700345); GO_0070328 (EC: IMP, PMID: 8827523) PMID: 8530039; 8827523; 8910501; 10996355; 11752456; 12032151; 12477932; 12700345; 15489334; 16335952; 16344560; 16763159; 17154273; 18193043; 18193044; 18802019; 18809223; 19060906; 19197348; 19336475; 19913121; 20331378; 20430392; 20498921; 20571754; 20602615; 20628086; 20714348; 20855565; 20864672; 20972250; 21103663; 21943158 apolipoprotein C-IV Ensembl:ENSG00000267467 HGNC:611 HPRD:02848 MIM:600745 Vega:OTTHUMG00000180845 APOC4 Bin Zhao, Yue Liu, Oliver He AD2 LDLCQ5 LPG WEB: http://www.ncbi.nlm.nih.gov/gene APOE apolipoprotein E 348 19q13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000302 (EC: NAS, PMID: 11743999); GO_0001523 (EC: TAS); GO_0001540 (EC: IDA, PMID: 11305869); GO_0001937 (EC: IDA, PMID: 9685360); GO_0002021 (EC: IEA); GO_0005319 (EC: IDA, PMID: 17305370); GO_0005515 (EC: IPI, PMID: 12950167); GO_0005543 (EC: IDA, PMID: 4066713); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA); GO_0005737 (EC: NAS, PMID: 8083695); GO_0005737 (EC: TAS, PMID: 9622609); GO_0005769 (EC: TAS); GO_0005770 (EC: IEA); GO_0005794 (EC: IEA); GO_0005886 (EC: TAS); GO_0006641 (EC: IDA, PMID: 9649566); GO_0006641 (EC: IMP, PMID: 3771793); GO_0006707 (EC: IEA); GO_0006874 (EC: IEA); GO_0006898 (EC: IDA, PMID: 1917954); GO_0007010 (EC: TAS, PMID: 9622609); GO_0007186 (EC: IDA, PMID: 16443932); GO_0007263 (EC: IDA, PMID: 8995232); GO_0007271 (EC: TAS, PMID: 9622609); GO_0007568 (EC: IEA); GO_0007603 (EC: TAS); GO_0008201 (EC: IDA, PMID: 2745454); GO_0008203 (EC: IDA, PMID: 9649566); GO_0008203 (EC: IMP, PMID: 3771793); GO_0008219 (EC: IEA); GO_0008289 (EC: IDA, PMID: 4066713); GO_0010544 (EC: IDA, PMID: 8995232); GO_0010873 (EC: IDA, PMID: 15654758); GO_0010875 (EC: IDA, PMID: 14754908); GO_0010875 (EC: IGI, PMID: 12401887); GO_0014012 (EC: IEA); GO_0016209 (EC: IDA, PMID: 9685360); GO_0017127 (EC: IEA); GO_0019934 (EC: IDA, PMID: 8995232); GO_0030195 (EC: IDA, PMID: 8995232); GO_0030425 (EC: NAS, PMID: 8083695); GO_0030516 (EC: TAS, PMID: 9622609); GO_0030828 (EC: IDA, PMID: 8995232); GO_0031232 (EC: IEA); GO_0032489 (EC: IDA, PMID: 16443932); GO_0032526 (EC: IEA); GO_0032805 (EC: IDA, PMID: 15950758); GO_0032868 (EC: IEA); GO_0033344 (EC: IDA, PMID: 11162594); GO_0033700 (EC: IDA, PMID: 11162594); GO_0034361 (EC: IDA, PMID: 17154273); GO_0034362 (EC: IDA, PMID: 8245722); GO_0034363 (EC: IDA, PMID: 17336988); GO_0034364 (EC: IDA, PMID: 210174); GO_0034372 (EC: IDA, PMID: 15654758); GO_0034372 (EC: IGI, PMID: 12401887); GO_0034374 (EC: IEA); GO_0034375 (EC: IGI, PMID: 12401887); GO_0034380 (EC: IDA, PMID: 17305370); GO_0034382 (EC: IMP, PMID: 7175379); GO_0034384 (EC: IDA, PMID: 210175); GO_0034447 (EC: IDA, PMID: 1917954); GO_0034447 (EC: IMP, PMID: 9649566); GO_0042157 (EC: TAS); GO_0042158 (EC: IEA); GO_0042159 (EC: IEA); GO_0042311 (EC: IEA); GO_0042627 (EC: IDA, PMID: 16935699); GO_0042632 (EC: IDA, PMID: 9649566); GO_0042802 (EC: IDA, PMID: 4066713); GO_0042803 (EC: IPI, PMID: 8245722); GO_0043025 (EC: NAS, PMID: 8083695); GO_0043407 (EC: IDA, PMID: 9685360); GO_0043524 (EC: IEA); GO_0043537 (EC: IDA, PMID: 9685360); GO_0043691 (EC: IDA, PMID: 8127890); GO_0044281 (EC: TAS); GO_0045471 (EC: IEA); GO_0045541 (EC: IDA, PMID: 1917954); GO_0045773 (EC: IEA); GO_0046848 (EC: IEA); GO_0046907 (EC: TAS, PMID: 9622609); GO_0046911 (EC: IDA, PMID: 9685360); GO_0048156 (EC: IPI, PMID: 7566652); GO_0048168 (EC: TAS, PMID: 9622609); GO_0048709 (EC: IEA); GO_0048844 (EC: IEA); GO_0050728 (EC: IC, PMID: 8995232); GO_0050750 (EC: IDA, PMID: 210175); GO_0050750 (EC: IPI, PMID: 17326667); GO_0051000 (EC: IDA, PMID: 8995232); GO_0051044 (EC: IDA, PMID: 15950758); GO_0051651 (EC: IEA); GO_0060228 (EC: IDA, PMID: 15654758); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070326 (EC: IDA, PMID: 1384047); GO_0070326 (EC: IPI, PMID: 12950167); GO_0071347 (EC: IEA); GO_0071363 (EC: IEA); GO_0071397 (EC: IEA); GO_0071682 (EC: TAS); GO_0071813 (EC: IEA); GO_0072562 (EC: IDA) PMID: 210174; 210175; 759055; 1356443; 1360898; 1361196; 1384047; 1617762; 1674745; 1713245; 1730728; 1917954; 2063194; 2101409; 2313204; 2341812; 2470732; 2498325; 2539388; 2556398; 2738044; 2745454; 2760009; 2779654; 2851587; 2987927; 2992507; 3038959; 3243553; 3283935; 3771793; 3922972; 3947350; 4066713; 4345202; 6199196; 6289314; 6323533; 6325438; 6327682; 6897404; 7068630; 7175379; 7263700; 7498414; 7566652; 7581381; 7586659; 7635945; 7761390; 7768901; 7797576; 7833947; 7972031; 8063017; 8083695; 8127890; 8245722; 8287539; 8300609; 8346443; 8488843; 8620924; 8624078; 8626535; 8756331; 8995232; 9012418; 9147408; 9218423; 9236223; 9360638; 9512010; 9622609; 9649566; 9685360; 9831625; 9869645; 9931331; 10520737; 10559559; 10662539; 10850798; 10962542; 10993992; 11030801; 11032626; 11033977; 11042151; 11055796; 11058710; 11060506; 11061249; 11063158; 11064931; 11072138; 11074789; 11076057; 11079660; 11095479; 11095526; 11096027; 11099722; 11100124; 11106322; 11109009; 11110974; 11113217; 11118024; 11118260; 11118404; 11118932; 11119301; 11121165; 11125748; 11126401; 11129109; 11129992; 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23581910; 23583468; 23584199; 23587637; 23587689; 23588940; 23590983; 23593485; 23603214; 23612909; 23613766; 23620513; 23624169; 23631810; 23631828; 23642733; 23652625; 23660682; 23663404; 23669301; 23684315; 23687437; 23701536; 23723060; 23726366; 23729930; 23731072; 23737466; 23743349; 23769398; 23771217; 23773371; 23779114; 23786792; 23808899; 23815818; 23826174; 23844046; 23844141; 23855979; 23865355; 23876113; 23883936; 23888546; 23902934; 23902937; 23919842; 23965289; 24009459; 24023260; 24023310; 24023758; 24145446; 24145819; 24163986; 24239320; 24276092; 24291031; 24308640; 24340925; 24448836; 24464001 apolipoprotein E Alzpathway: APOE-cholesterol transport. Source: https://pubmed.ncbi.nlm.nih.gov/23620513/ Alzpathway: LRP8-APOE association. Source: https://pubmed.ncbi.nlm.nih.gov/17428983/ Alzpathway: VLDLR-APOE association. Source: https://pubmed.ncbi.nlm.nih.gov/28292942/ Ensembl:ENSG00000130203 HGNC:613 HPRD:00135 MIM:107741 Vega:OTTHUMG00000128901 APOE Bin Zhao, Yue Liu, Oliver He AAA ABETA ABPP AD1 APPI CTFgamma CVAP PN-II PN2 WEB: http://www.ncbi.nlm.nih.gov/gene APP amyloid beta (A4) precursor protein 351 21q21.3 20140408 9606 21 protein-coding Official from a nomenclature committee GO_0000085 (EC: ISS); GO_0001967 (EC: IEA); GO_0002576 (EC: TAS); GO_0003677 (EC: ISS); GO_0004867 (EC: IDA, PMID: 10652580); GO_0005102 (EC: IPI, PMID: 19849849); GO_0005515 (EC: IPI, PMID: 10049767); GO_0005576 (EC: TAS); GO_0005737 (EC: IDA, PMID: 18509662); GO_0005737 (EC: ISS); GO_0005794 (EC: IDA); GO_0005794 (EC: ISS); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 12805363); GO_0005887 (EC: TAS, PMID: 10806211); GO_0005905 (EC: IEA); GO_0006378 (EC: ISS); GO_0006417 (EC: ISS); GO_0006468 (EC: ISS); GO_0006878 (EC: ISS); GO_0006897 (EC: ISS); GO_0006979 (EC: IEA); GO_0007155 (EC: IEA); GO_0007176 (EC: ISS); GO_0007219 (EC: IEA); GO_0007409 (EC: ISS); GO_0007596 (EC: TAS); GO_0007617 (EC: ISS); GO_0007626 (EC: ISS); GO_0008088 (EC: ISS); GO_0008201 (EC: IEA); GO_0008203 (EC: IEA); GO_0008344 (EC: ISS); GO_0008542 (EC: ISS); GO_0009986 (EC: IDA, PMID: 7593229); GO_0010951 (EC: IDA, PMID: 10652580); GO_0010971 (EC: IEA); GO_0016021 (EC: ISS); GO_0016199 (EC: ISS); GO_0016322 (EC: ISS); GO_0016358 (EC: ISS); GO_0016504 (EC: IEA); GO_0030168 (EC: TAS); GO_0030198 (EC: ISS); GO_0030198 (EC: TAS); GO_0030424 (EC: ISS); GO_0030900 (EC: IEA); GO_0031093 (EC: TAS); GO_0031175 (EC: ISS); GO_0031594 (EC: IEA); GO_0033130 (EC: IPI, PMID: 10681545); GO_0035235 (EC: ISS); GO_0035253 (EC: IEA); GO_0035872 (EC: TAS); GO_0040014 (EC: ISS); GO_0042802 (EC: IPI, PMID: 16193067); GO_0043197 (EC: IDA, PMID: 11988176); GO_0043198 (EC: IDA, PMID: 11988176); GO_0043231 (EC: IDA); GO_0043235 (EC: IDA); GO_0043393 (EC: IEA); GO_0045087 (EC: TAS); GO_0045177 (EC: IEA); GO_0045202 (EC: IDA, PMID: 11988176); GO_0045665 (EC: IEA); GO_0045931 (EC: ISS); GO_0045944 (EC: IEA); GO_0046914 (EC: IEA); GO_0048471 (EC: IDA); GO_0048669 (EC: ISS); GO_0050803 (EC: ISS); GO_0050885 (EC: IEA); GO_0051124 (EC: IEA); GO_0051233 (EC: IEA); GO_0051402 (EC: IMP, PMID: 19225519); GO_0051425 (EC: IPI, PMID: 12805363); GO_0051563 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19199708); GO_0070851 (EC: IEA) PMID: 1302033; 1303239; 1303244; 1303275; 1307241; 1353447; 1363811; 1415269; 1587857; 1671712; 1678058; 1679289; 1707846; 1718421; 1907279; 1908231; 1908403; 1925564; 1944558; 1969731; 2110105; 2110384; 2111584; 2119582; 2125487; 2190106; 2506449; 2507928; 2538123; 2569763; 2675837; 2783775; 2834384; 2881207; 2893289; 2893290; 2893291; 2893379; 2900137; 2949367; 3035574; 3140222; 3159021; 3312495; 3597385; 3810169; 7516706; 7523115; 7543026; 7556457; 7568089; 7588758; 7593229; 7686976; 7688497; 7699335; 7737970; 7793988; 7913895; 8032873; 8102836; 8109908; 8131745; 8154870; 8158260; 8229004; 8239320; 8248178; 8267572; 8290042; 8328966; 8344894; 8446172; 8473906; 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22710909; 22711819; 22711829; 22717612; 22718756; 22721728; 22733824; 22734645; 22739235; 22742657; 22745165; 22747709; 22750418; 22751175; 22753410; 22755192; 22763024; 22767595; 22778803; 22785403; 22786606; 22801430; 22801501; 22813427; 22814377; 22823461; 22828513; 22845771; 22851182; 22867029; 22869680; 22872014; 22874667; 22874668; 22874669; 22874673; 22878163; 22879596; 22879628; 22886024; 22886025; 22886847; 22888099; 22891241; 22898766; 22902274; 22903058; 22910355; 22910376; 22910909; 22915585; 22935789; 22935999; 22940426; 22940640; 22944394; 22949636; 22954667; 22954671; 22975281; 22975585; 22976074; 22987042; 22988239; 22992745; 22996644; 23000965; 23012332; 23015407; 23018285; 23021373; 23022042; 23022323; 23024364; 23025283; 23026200; 23033480; 23036978; 23040034; 23041958; 23043097; 23043377; 23047754; 23054636; 23058290; 23060451; 23064434; 23065792; 23069872; 23071163; 23077040; 23084776; 23089603; 23095849; 23102935; 23115236; 23117496; 23129766; 23129776; 23132858; 23133593; 23143229; 23152608; 23160010; 23160011; 23163430; 23175838; 23179400; 23204056; 23209707; 23224319; 23224999; 23225009; 23225334; 23225543; 23229789; 23237523; 23241555; 23244427; 23253155; 23254632; 23254640; 23261462; 23262221; 23271316; 23276885; 23283972; 23289528; 23291095; 23293020; 23294492; 23297063; 23298733; 23317003; 23325603; 23330981; 23337342; 23337872; 23344882; 23358498; 23364138; 23368879; 23380070; 23380992; 23382922; 23386614; 23388171; 23388172; 23396350; 23413683; 23415897; 23421682; 23423136; 23427915; 23430745; 23445400; 23447675; 23453155; 23458258; 23474291; 23474850; 23477989; 23479184; 23479202; 23481686; 23481704; 23493873; 23509973; 23509974; 23509981; 23509983; 23515399; 23520537; 23520540; 23525105; 23525278; 23525279; 23528367; 23536396; 23552118; 23553344; 23554170; 23555563; 23557734; 23575575; 23575824; 23576130; 23576620; 23577068; 23577177; 23582659; 23583290; 23583777; 23584198; 23587139; 23588697; 23596051; 23597280; 23612608; 23614875; 23616534; 23620513; 23640054; 23648516; 23660814; 23660953; 23666174; 23687299; 23704887; 23710041; 23712469; 23713656; 23737042; 23742273; 23748737; 23773908; 23775077; 23776240; 23779022; 23779114; 23789343; 23792961; 23824268; 23831058; 23840007; 23845280; 23846683; 23853087; 23860354; 23865807; 23872114; 23884929; 23888782; 23891752; 23895422; 23897820; 23900411; 23902769; 23904197; 23907250; 23907271; 23907583; 23926111; 23948569; 23959870; 23959898; 23965993; 23973487; 23986449; 24016775; 24022491; 24041501; 24052255; 24063855; 24067654; 24086147; 24117942; 24174666; 24176981; 24212387; 24225352; 24225948; 24247242; 24383085; 24431460; 24448836; 24457600 amyloid beta (A4) precursor protein Alzpathway: APP-SORL1 association. Source: https://pubmed.ncbi.nlm.nih.gov/16174740/ Ensembl:ENSG00000142192 HGNC:620 HPRD:00100 MIM:104760 Vega:OTTHUMG00000078438 APP Bin Zhao, Yue Liu, Oliver He ALPS1A APO-1 APT1 CD95 FAS1 FASTM TNFRSF6 WEB: http://www.ncbi.nlm.nih.gov/gene FAS Fas cell surface death receptor 355 RP11-399O19.7 10q24.1 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0002377 (EC: IEA); GO_0003014 (EC: IEA); GO_0004871 (EC: TAS, PMID: 10875918); GO_0004872 (EC: NAS, PMID: 7533181); GO_0004888 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10918185); GO_0005634 (EC: IDA); GO_0005737 (EC: IDA); GO_0005829 (EC: NAS, PMID: 7533181); GO_0005886 (EC: IDA); GO_0005886 (EC: IMP); GO_0005886 (EC: TAS); GO_0006461 (EC: TAS, PMID: 10875918); GO_0006915 (EC: IDA, PMID: 9681877); GO_0006915 (EC: TAS); GO_0006919 (EC: TAS); GO_0006924 (EC: IEA); GO_0006925 (EC: IEA); GO_0006927 (EC: IEA); GO_0007165 (EC: TAS, PMID: 9360929); GO_0008625 (EC: IEA); GO_0009636 (EC: IEA); GO_0009897 (EC: IEA); GO_0009986 (EC: IDA); GO_0016021 (EC: IEA); GO_0019724 (EC: IEA); GO_0019900 (EC: IPI, PMID: 7538908); GO_0031264 (EC: IDA, PMID: 11101870); GO_0031265 (EC: IDA); GO_0032464 (EC: IEA); GO_0042802 (EC: IPI); GO_0042981 (EC: NAS, PMID: 7533181); GO_0043065 (EC: IDA); GO_0043065 (EC: IMP); GO_0043066 (EC: IEA); GO_0045060 (EC: IEA); GO_0045121 (EC: IDA); GO_0045619 (EC: IEA); GO_0045637 (EC: IEA); GO_0048536 (EC: IEA); GO_0050869 (EC: IEA); GO_0051260 (EC: IEA); GO_0051384 (EC: IEA); GO_0070062 (EC: IDA); GO_0071260 (EC: IEP, PMID: 19593445); GO_0071285 (EC: IEA); GO_0071455 (EC: IMP); GO_0097049 (EC: IEA); GO_0097190 (EC: TAS); GO_0097191 (EC: IMP); GO_0097192 (EC: IEA); GO_0097527 (EC: IMP, PMID: 16507998); GO_2001239 (EC: TAS); GO_2001241 (EC: IEA) PMID: 1375228; 1385299; 1385309; 1713127; 2469768; 2787530; 7510905; 7514572; 7529798; 7530336; 7533181; 7536190; 7536343; 7538907; 7538908; 7539892; 7540117; 7542559; 7543095; 7575433; 7859281; 8521815; 8524870; 8598453; 8626376; 8648105; 8681376; 8780394; 8864141; 8906799; 8929361; 8940097; 8967952; 8976184; 9002959; 9028321; 9028957; 9039262; 9045686; 9079683; 9082980; 9126929; 9159204; 9199966; 9208847; 9215629; 9223324; 9226175; 9228058; 9247148; 9257699; 9263011; 9267021; 9268734; 9322534; 9325248; 9360929; 9427646; 9475352; 9560245; 9681877; 9721089; 9727492; 9740801; 9751072; 9787134; 9821419; 9835052; 9847311; 9857224; 9920849; 9927496; 9971775; 10068040; 10072505; 10090885; 10200300; 10235259; 10340403; 10462485; 10505674; 10506221; 10535980; 10542291; 10620127; 10625668; 10630977; 10671224; 10706119; 10709732; 10713117; 10799864; 10871852; 10875918; 10918185; 10978533; 11003656; 11034606; 11035039; 11036836; 11048727; 11048730; 11101867; 11101870; 11112409; 11129341; 11177389; 11193028; 11208609; 11298454; 11323689; 11418480; 11436125; 11483955; 11495919; 11550967; 11606059; 11692157; 11733515; 11771526; 11773067; 11779855; 11782802; 11786482; 11786908; 11788891; 11790791; 11809905; 11824955; 11830507; 11836578; 11857317; 11861273; 11864613; 11867183; 11877055; 11891278; 11895550; 11909874; 11920253; 11941452; 11949822; 11961305; 11965496; 11975981; 11986289; 11994542; 12021072; 12032668; 12034188; 12037669; 12040174; 12049185; 12060388; 12060768; 12064832; 12067476; 12096347; 12096925; 12098516; 12107169; 12131184; 12137598; 12139945; 12140383; 12150947; 12163388; 12169207; 12177303; 12185583; 12188927; 12196516; 12198154; 12207331; 12207908; 12220552; 12221075; 12234263; 12244143; 12270344; 12324452; 12372427; 12388693; 12393468; 12393649; 12393889; 12397013; 12414525; 12415011; 12419941; 12452031; 12455036; 12466128; 12477932; 12482410; 12482505; 12485855; 12497631; 12507389; 12513829; 12515395; 12515623; 12516573; 12557947; 12581154; 12583439; 12586732; 12587820; 12604424; 12623840; 12629150; 12646947; 12679613; 12698366; 12699879; 12702723; 12706861; 12710855; 12717632; 12724420; 12742662; 12742739; 12753742; 12757469; 12770553; 12783210; 12788915; 12794152; 12803240; 12824926; 12855571; 12855687; 12867600; 12874203; 12880639; 12883671; 12887920; 12907599; 12923319; 12952224; 12963547; 14506242; 14512182; 14514471; 14530312; 14533029; 14534720; 14557654; 14573612; 14585083; 14594800; 14625033; 14625298; 14625471; 14637155; 14638442; 14644092; 14644197; 14644318; 14647422; 14668794; 14672901; 14676203; 14694156; 14698859; 14714559; 14719092; 14719118; 14724564; 14736971; 14739003; 14739535; 14739941; 14745445; 14759258; 14967838; 14977837; 14981943; 14991945; 15016553; 15019807; 15039424; 15042330; 15054468; 15055260; 15078899; 15138553; 15159312; 15159409; 15160902; 15161716; 15183989; 15203866; 15207703; 15214041; 15215233; 15218339; 15220220; 15238425; 15240787; 15251990; 15277733; 15280387; 15287856; 15289903; 15297424; 15301860; 15345718; 15365741; 15383280; 15390286; 15459302; 15465831; 15467462; 15480430; 15489334; 15492869; 15497017; 15500551; 15502938; 15514680; 15542843; 15556626; 15556941; 15557123; 15563545; 15592292; 15617242; 15632129; 15637757; 15641141; 15645122; 15659383; 15665818; 15670977; 15672026; 15680394; 15688389; 15695771; 15704653; 15723707; 15726829; 15748958; 15786554; 15795317; 15803113; 15806311; 15808689; 15816832; 15818415; 15829968; 15833141; 15838728; 15843521; 15855233; 15858021; 15860671; 15894356; 15907374; 15911745; 15917238; 15929764; 15936090; 15937082; 15938782; 15944736; 15962371; 15963548; 15967797; 15968727; 15972662; 15975999; 15996722; 16000573; 16018969; 16081586; 16087126; 16091761; 16124644; 16129703; 16143308; 16148554; 16157125; 16158329; 16163374; 16169070; 16215672; 16215685; 16255757; 16273638; 16304056; 16306044; 16313826; 16343245; 16344560; 16358967; 16364925; 16368755; 16385451; 16393952; 16403915; 16436054; 16438619; 16441482; 16463650; 16469115; 16472594; 16473667; 16474169; 16507928; 16507998; 16515587; 16524887; 16538171; 16538172; 16643620; 16691186; 16723718; 16736614; 16741989; 16750039; 16765090; 16788566; 16808908; 16820946; 16822901; 16895904; 16899302; 16914910; 16917513; 16921240; 16936193; 16937440; 16948902; 16972019; 16987075; 17000697; 17006606; 17009393; 17014078; 17014925; 17053166; 17056024; 17062728; 17130290; 17135269; 17159907; 17159908; 17161551; 17174268; 17183065; 17194564; 17195092; 17198275; 17203787; 17219051; 17336828; 17376892; 17406980; 17465232; 17485109; 17487740; 17493146; 17504511; 17516614; 17544837; 17545588; 17559541; 17561354; 17564320; 17589525; 17597021; 17598974; 17603079; 17622942; 17657164; 17657791; 17667965; 17684774; 17692455; 17704746; 17704785; 17708363; 17724145; 17762757; 17853317; 17878356; 17891455; 17909299; 17912028; 17912957; 17916181; 17932249; 17938571; 17941899; 17962219; 17962369; 17970696; 17978477; 17982483; 17993614; 17997887; 18000680; 18003704; 18029348; 18045865; 18056484; 18057579; 18068525; 18078642; 18078929; 18088463; 18090928; 18162459; 18174230; 18208868; 18217400; 18220834; 18227168; 18234961; 18243739; 18268284; 18292515; 18302883; 18316328; 18324486; 18328427; 18337305; 18342935; 18361934; 18383830; 18411295; 18422813; 18427836; 18439588; 18441236; 18445624; 18463097; 18473402; 18483392; 18488389; 18494554; 18505906; 18508922; 18508927; 18512812; 18548110; 18552209; 18561948; 18582468; 18588573; 18609513; 18614439; 18635548; 18666137; 18676032; 18679533; 18685642; 18718055; 18727868; 18753860; 18754288; 18757527; 18787411; 18796602; 18800686; 18804468; 18813857; 18818748; 18844072; 18844210; 18851835; 18854777; 18923451; 18948840; 18949391; 18949744; 18972838; 19004284; 19009351; 19010354; 19012493; 19015953; 19019335; 19019483; 19020991; 19037097; 19043361; 19047119; 19067240; 19073786; 19076218; 19077906; 19103758; 19112091; 19118384; 19125371; 19141320; 19141860; 19146781; 19155494; 19161534; 19168581; 19170196; 19173804; 19181929; 19219602; 19225810; 19240174; 19241965; 19262492; 19263494; 19266094; 19270351; 19272297; 19293475; 19298528; 19305072; 19332441; 19336370; 19391241; 19404646; 19458913; 19480241; 19487421; 19509307; 19521670; 19527514; 19538867; 19538884; 19542541; 19561642; 19565204; 19572057; 19573080; 19593445; 19615968; 19625176; 19628789; 19634684; 19653342; 19669200; 19680267; 19692168; 19692467; 19698994; 19716115; 19718569; 19723039; 19726736; 19737931; 19751723; 19758996; 19759548; 19766542; 19773279; 19788921; 19789190; 19798106; 19810143; 19811416; 19812265; 19817952; 19826071; 19890662; 19895798; 19911702; 19913121; 19926197; 19927299; 19937732; 19940360; 19941645; 19950259; 19954064; 19966861; 20012528; 20052288; 20064083; 20074157; 20085233; 20101431; 20106900; 20137575; 20140262; 20164160; 20181888; 20187936; 20193111; 20204402; 20205514; 20219325; 20222173; 20237496; 20301287; 20352431; 20353032; 20359312; 20360470; 20378664; 20380574; 20385987; 20393185; 20394629; 20396760; 20396799; 20408337; 20416077; 20438363; 20438666; 20453000; 20470393; 20501759; 20505730; 20534173; 20547950; 20553075; 20558744; 20568250; 20572163; 20618494; 20620960; 20628086; 20629322; 20638642; 20658220; 20666744; 20673483; 20682001; 20694011; 20726226; 20737708; 20800603; 20802294; 20813889; 20819778; 20822933; 20842669; 20876301; 20934723; 20935634; 20936988; 20947025; 20951677; 20953611; 20959405; 20960177; 20981796; 21036138; 21041692; 21048031; 21049406; 21076068; 21081533; 21087335; 21103345; 21107705; 21120501; 21131755; 21145805; 21167737; 21173302; 21196076; 21233219; 21250890; 21257927; 21271302; 21286777; 21317766; 21321117; 21324892; 21354149; 21359408; 21382479; 21390503; 21430781; 21454681; 21466843; 21468569; 21485506; 21490157; 21516345; 21518761; 21526201; 21526501; 21528407; 21530489; 21549565; 21550977; 21557211; 21557277; 21613217; 21619451; 21625619; 21651830; 21691772; 21706480; 21717192; 21729539; 21741956; 21752354; 21757675; 21762074; 21792914; 21793106; 21803845; 21806408; 21808135; 21852034; 21864388; 21864851; 21869830; 21879377; 21885602; 21906983; 21910009; 21912376; 21917312; 21940365; 21961589; 21963094; 21971214; 21988832; 22027769; 22036455; 22042271; 22065776; 22076446; 22084312; 22095627; 22147197; 22173501; 22182632; 22183068; 22186140; 22194871; 22197557; 22199270; 22207003; 22211869; 22237435; 22252758; 22285488; 22299671; 22331638; 22344564; 22352690; 22357491; 22364882; 22386066; 22398398; 22422199; 22425739; 22431000; 22438247; 22492046; 22499988; 22508480; 22609371; 22622132; 22631677; 22645131; 22649200; 22669972; 22670178; 22677152; 22683265; 22698280; 22702044; 22706245; 22726303; 22752343; 22771321; 22805310; 22806078; 22815944; 22821704; 22842170; 22864571; 22891283; 22898262; 22934709; 22946667; 22983578; 22992806; 23033661; 23045958; 23053964; 23065220; 23114924; 23152563; 23153021; 23166734; 23234803; 23235765; 23240581; 23251661; 23269121; 23280017; 23285481; 23322903; 23326385; 23326448; 23326557; 23327061; 23330016; 23333919; 23338968; 23364796; 23372841; 23392773; 23420824; 23430061; 23434371; 23492187; 23499736; 23524443; 23580232; 23582102; 23582741; 23590971; 23618817; 23619472; 23636796; 23662689; 23667901; 23681795; 23697029; 23762329; 23770605; 23792529; 23846229; 23865866; 23880344; 23894399; 23900676; 23923075; 23932896; 23979975; 24014103; 24043286; 24091673; 24178789; 24331540 Fas cell surface death receptor Ensembl:ENSG00000026103 HGNC:11920 HPRD:00609 MIM:134637 Vega:OTTHUMG00000018701 FAS Bin Zhao, Yue Liu, Oliver He ARH12 ARHA RHO12 RHOH12 WEB: http://www.ncbi.nlm.nih.gov/gene RHOA ras homolog family member A 387 3p21.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0003924 (EC: TAS, PMID: 10436159); GO_0005515 (EC: IPI, PMID: 10051605); GO_0005525 (EC: IEA); GO_0005829 (EC: TAS); GO_0005856 (EC: IEA); GO_0005886 (EC: TAS); GO_0005938 (EC: IDA, PMID: 16103226); GO_0006184 (EC: TAS, PMID: 10436159); GO_0007179 (EC: TAS); GO_0007264 (EC: TAS); GO_0007266 (EC: TAS, PMID: 10436159); GO_0007411 (EC: TAS); GO_0007596 (EC: TAS); GO_0016032 (EC: IEA); GO_0017022 (EC: IPI, PMID: 15644318); GO_0021762 (EC: IEP); GO_0030027 (EC: ISS); GO_0030036 (EC: TAS, PMID: 10436159); GO_0030054 (EC: TAS); GO_0030168 (EC: TAS); GO_0030334 (EC: IMP, PMID: 19934221); GO_0030496 (EC: IEA); GO_0032154 (EC: IEA); GO_0032467 (EC: IMP, PMID: 16103226); GO_0033688 (EC: ISS); GO_0036089 (EC: IDA, PMID: 16103226); GO_0042346 (EC: NAS, PMID: 12761501); GO_0043123 (EC: IEP, PMID: 12761501); GO_0043296 (EC: IDA); GO_0043297 (EC: IMP); GO_0043931 (EC: ISS); GO_0045666 (EC: IMP, PMID: 17488780); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0050770 (EC: TAS); GO_0050771 (EC: TAS); GO_0050772 (EC: TAS); GO_0051056 (EC: TAS); GO_0051496 (EC: IDA, PMID: 15467718); GO_0061383 (EC: ISS); GO_0070062 (EC: IDA, PMID: 19056867); GO_0090307 (EC: IMP, PMID: 19635168) PMID: 1328215; 1556108; 2407642; 3822842; 7835413; 7989340; 8039707; 8125298; 8491184; 8543060; 8571127; 8617235; 8641286; 8662891; 8769096; 8798490; 8816443; 8910519; 9113980; 9121475; 9199174; 9302995; 9354661; 9407060; 9446575; 9490022; 9535835; 9535855; 9545299; 9548756; 9565577; 9582072; 9605859; 9614111; 9635436; 9647788; 9799233; 9804788; 9857026; 10051605; 10066731; 10220378; 10388627; 10436159; 10489445; 10523675; 10526156; 10595511; 10619026; 10713718; 10748207; 10854437; 10896672; 10940294; 10947987; 10948190; 11085924; 11149925; 11157984; 11162552; 11284700; 11311142; 11335720; 11350930; 11368848; 11373293; 11432776; 11560922; 11591790; 11672528; 11689693; 11696353; 11741970; 11751986; 11779461; 11786539; 11788600; 11818523; 11822867; 11830497; 11830597; 11839748; 11839765; 11889037; 11907271; 11909943; 11927263; 11948427; 11998687; 12006984; 12016230; 12062101; 12071848; 12093360; 12115629; 12119292; 12154081; 12169092; 12221077; 12221096; 12244193; 12397214; 12401808; 12423633; 12432077; 12445208; 12446789; 12454018; 12466390; 12477932; 12482610; 12490434; 12515866; 12524425; 12533515; 12534282; 12538863; 12579323; 12584113; 12593858; 12654918; 12692008; 12692556; 12719789; 12748184; 12761501; 12766172; 12773565; 12777804; 12805219; 12808121; 12842009; 12847276; 12857875; 12879077; 12900402; 12938929; 12939257; 12944407; 12951563; 12972426; 12972601; 14506264; 14514689; 14530271; 14581471; 14605490; 14612927; 14644158; 14657501; 14660612; 14749388; 15003991; 15009099; 15016733; 15023524; 15068789; 15069594; 15075243; 15085137; 15096506; 15102021; 15102857; 15125835; 15128850; 15155793; 15184877; 15208091; 15210811; 15298851; 15308673; 15322077; 15331592; 15448013; 15467718; 15475352; 15475381; 15489334; 15530360; 15535843; 15557193; 15574779; 15579505; 15598682; 15611088; 15640525; 15642170; 15643515; 15644318; 15652748; 15659383; 15668138; 15670823; 15710384; 15755723; 15761153; 15766663; 15793564; 15793569; 15809302; 15817453; 15834426; 15843433; 15864301; 15889147; 15890975; 15901767; 15925904; 15963982; 16061799; 16103226; 16105876; 16109481; 16112081; 16118207; 16188938; 16196087; 16215275; 16247472; 16257181; 16308318; 16352658; 16394104; 16397238; 16402387; 16424340; 16427251; 16472676; 16481321; 16496227; 16513651; 16537448; 16540523; 16622418; 16632465; 16644720; 16645187; 16652149; 16681996; 16684954; 16772297; 16776827; 16864657; 16904289; 16978776; 16996686; 17007568; 17018591; 17018860; 17077126; 17086988; 17115030; 17130286; 17142836; 17178865; 17190792; 17197445; 17273773; 17284169; 17300916; 17301291; 17301947; 17310253; 17318188; 17332506; 17335080; 17353931; 17360533; 17446864; 17488622; 17488780; 17492768; 17493936; 17502338; 17507466; 17517067; 17562701; 17572668; 17597401; 17635521; 17636025; 17658517; 17673200; 17702745; 17719543; 17825823; 17855350; 17896152; 17914970; 17940286; 17947237; 17947676; 17951409; 17976533; 18005700; 18005701; 18078809; 18079197; 18088600; 18096806; 18172303; 18182571; 18198190; 18287089; 18287519; 18292502; 18300342; 18314880; 18316594; 18334926; 18356691; 18434237; 18445682; 18458160; 18477564; 18495213; 18509267; 18509476; 18524772; 18541705; 18567581; 18575772; 18593598; 18628484; 18651974; 18653556; 18660502; 18687805; 18688040; 18694745; 18713748; 18721871; 18751372; 18757369; 18757503; 18781093; 18824598; 18827818; 18829495; 18835241; 18844232; 18851832; 18922893; 18923442; 18929667; 18937283; 18948190; 18953413; 18955552; 18983771; 18996344; 18996642; 19015318; 19038009; 19049388; 19056867; 19103606; 19147496; 19147561; 19151751; 19152186; 19173301; 19234490; 19265130; 19293150; 19306108; 19318350; 19372585; 19391109; 19403695; 19421144; 19443661; 19451223; 19470470; 19477269; 19487339; 19499974; 19506078; 19509057; 19527220; 19533666; 19550117; 19573309; 19586902; 19602845; 19620060; 19620624; 19625450; 19635168; 19635823; 19642867; 19644046; 19651782; 19654316; 19680746; 19682162; 19726670; 19752040; 19762715; 19772916; 19773279; 19776349; 19782033; 19787194; 19794400; 19798549; 19805522; 19826000; 19857574; 19911011; 19912238; 19913121; 19934221; 19944695; 19956681; 20006706; 20026602; 20030946; 20041165; 20056178; 20061625; 20068229; 20130732; 20140537; 20195357; 20220547; 20223287; 20236512; 20307617; 20348106; 20360068; 20363740; 20376724; 20383141; 20399237; 20403997; 20416077; 20429915; 20442409; 20457808; 20460433; 20473500; 20499158; 20503409; 20507639; 20547485; 20553488; 20554761; 20558775; 20591975; 20628086; 20628200; 20655307; 20660160; 20682776; 20696764; 20733052; 20801873; 20805359; 20808760; 20811682; 20814828; 20828398; 20856855; 20859068; 20877624; 20886658; 20937815; 20945370; 20971525; 21071443; 21079737; 21087931; 21112276; 21129722; 21130456; 21145500; 21161732; 21186079; 21208644; 21209619; 21212278; 21242305; 21257924; 21258369; 21265091; 21266463; 21273559; 21277858; 21281639; 21303778; 21351730; 21357687; 21390328; 21402695; 21439370; 21451048; 21454543; 21454546; 21475975; 21518791; 21534245; 21574962; 21575498; 21576392; 21600098; 21628952; 21643014; 21667311; 21698469; 21708152; 21739156; 21750647; 21756816; 21757538; 21779788; 21816819; 21858203; 21878647; 21890473; 21898412; 21906983; 21907186; 21917148; 21936715; 21963094; 21983114; 21987572; 21988832; 22001926; 22009749; 22041269; 22049212; 22070920; 22072711; 22087025; 22092654; 22114142; 22120672; 22161021; 22197032; 22226472; 22226621; 22228765; 22241857; 22242598; 22251897; 22275376; 22328514; 22361510; 22363817; 22456196; 22495072; 22500016; 22504159; 22505724; 22575513; 22583359; 22584506; 22593208; 22628549; 22645245; 22655072; 22673622; 22673745; 22699054; 22740689; 22750095; 22774404; 22820501; 22842919; 22854067; 22893699; 22907703; 22939629; 22949615; 22963825; 22984590; 22992742; 23000965; 23042265; 23057787; 23066013; 23070684; 23079622; 23166513; 23176180; 23195957; 23243284; 23283961; 23307872; 23322732; 23324271; 23361851; 23405219; 23418489; 23469924; 23488932; 23493395; 23500462; 23512987; 23521319; 23525486; 23536606; 23570668; 23613866; 23615712; 23620398; 23648482; 23658012; 23720748; 23726972; 23774217; 23828571; 23870313; 23895422; 23940119; 24043311; 24096540; 24178298; 24200678; 24240172; 24250222; 24297045; 24324133; 24333506; 24413734; 24413737 ras homolog family member A Ensembl:ENSG00000067560 HGNC:667 HPRD:01323 MIM:165390 Vega:OTTHUMG00000156838 RHOA Bin Zhao, Yue Liu, Oliver He ATP2A SERCA1 WEB: http://www.ncbi.nlm.nih.gov/gene ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 487 16p12.1 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0005388 (EC: IDA, PMID: 1329967); GO_0005509 (EC: IMP, PMID: 9405806); GO_0005509 (EC: ISS); GO_0005515 (EC: IPI, PMID: 9295312); GO_0005524 (EC: IEA); GO_0005524 (EC: ISS); GO_0005789 (EC: IDA, PMID: 11402072); GO_0005789 (EC: TAS); GO_0005793 (EC: ISS); GO_0006200 (EC: ISS); GO_0006816 (EC: IDA, PMID: 11402072); GO_0006816 (EC: IMP, PMID: 9405806); GO_0006942 (EC: IMP, PMID: 9405806); GO_0007596 (EC: TAS); GO_0008637 (EC: IMP, PMID: 19061639); GO_0016020 (EC: ISS); GO_0016021 (EC: NAS, PMID: 9405806); GO_0016529 (EC: ISS); GO_0016529 (EC: NAS, PMID: 8841193); GO_0031095 (EC: TAS); GO_0031448 (EC: IDA, PMID: 12479237); GO_0031673 (EC: IDA, PMID: 1329967); GO_0031674 (EC: IDA, PMID: 1329967); GO_0032470 (EC: IMP, PMID: 11402072); GO_0032471 (EC: IMP, PMID: 11402072); GO_0033017 (EC: IC, PMID: 8040329); GO_0033017 (EC: TAS, PMID: 11402072); GO_0034220 (EC: TAS); GO_0034704 (EC: IC, PMID: 11402072); GO_0034976 (EC: IMP, PMID: 19061639); GO_0042803 (EC: IPI, PMID: 11402072); GO_0045988 (EC: IMP, PMID: 10914677); GO_0048471 (EC: ISS); GO_0051561 (EC: IMP, PMID: 19061639); GO_0051659 (EC: IMP, PMID: 19061639); GO_0055085 (EC: TAS); GO_0070059 (EC: IMP, PMID: 19061639); GO_0070509 (EC: IMP, PMID: 8040329); GO_0070588 (EC: IDA, PMID: 1329967); GO_0090076 (EC: IDA, PMID: 8841193) PMID: 1329967; 1746562; 2842876; 2936465; 8040329; 8729696; 8825625; 8841193; 8889548; 9295312; 9367679; 9405806; 9575189; 9642673; 10551848; 10914677; 11402072; 11438520; 11526231; 12032137; 12477932; 12479237; 12525698; 12692302; 12975374; 14638697; 14702039; 15071553; 15718407; 15767202; 15972723; 16192278; 16410239; 16642550; 16754798; 16933204; 17010426; 17110338; 17728322; 18947188; 18953100; 19061639; 19079260; 19644701; 21145461; 21576492; 21726808; 21890473; 21906983; 21963094; 22505724; 22609207; 22939629; 23911890 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 Ensembl:ENSG00000196296 HGNC:811 HPRD:00157 MIM:108730 Vega:OTTHUMG00000131760 ATP2A1 Bin Zhao, Yue Liu, Oliver He BBC2 BCL2L8 WEB: http://www.ncbi.nlm.nih.gov/gene BAD BCL2-associated agonist of cell death 572 11q13.1 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0001836 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10949025); GO_0005543 (EC: IMP); GO_0005739 (EC: IDA); GO_0005741 (EC: IDA); GO_0005741 (EC: TAS); GO_0005829 (EC: IDA); GO_0005829 (EC: TAS); GO_0006007 (EC: IEA); GO_0006915 (EC: IDA, PMID: 19667065); GO_0006915 (EC: TAS, PMID: 7834748); GO_0006919 (EC: ISS); GO_0007173 (EC: TAS); GO_0008289 (EC: IDA, PMID: 19667065); GO_0008543 (EC: TAS); GO_0008625 (EC: IEA); GO_0008630 (EC: IEA); GO_0008656 (EC: IDA, PMID: 18402937); GO_0009749 (EC: IEA); GO_0010508 (EC: TAS, PMID: 18309324); GO_0010918 (EC: ISS); GO_0019050 (EC: IEA); GO_0019221 (EC: IEA); GO_0019901 (EC: IPI, PMID: 17270021); GO_0030346 (EC: IEA); GO_0032024 (EC: ISS); GO_0032355 (EC: IEA); GO_0032570 (EC: IEA); GO_0033133 (EC: ISS); GO_0033574 (EC: IEA); GO_0034201 (EC: IEA); GO_0035774 (EC: IEA); GO_0038095 (EC: TAS); GO_0042493 (EC: IEA); GO_0042542 (EC: IEA); GO_0042593 (EC: ISS); GO_0043065 (EC: IDA, PMID: 9388232); GO_0043065 (EC: IMP, PMID: 17289999); GO_0043065 (EC: TAS); GO_0043200 (EC: IEA); GO_0043280 (EC: IDA, PMID: 18402937); GO_0043422 (EC: IEA); GO_0044342 (EC: ISS); GO_0045087 (EC: TAS); GO_0045471 (EC: IEA); GO_0045579 (EC: IEA); GO_0045582 (EC: IEA); GO_0045862 (EC: IDA, PMID: 18387192); GO_0046031 (EC: ISS); GO_0046034 (EC: ISS); GO_0046902 (EC: IMP); GO_0046931 (EC: IDA, PMID: 19667065); GO_0046982 (EC: IEA); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0050679 (EC: IMP, PMID: 19593445); GO_0051384 (EC: IEA); GO_0051592 (EC: IEA); GO_0060139 (EC: IEA); GO_0060154 (EC: IEA); GO_0071247 (EC: IEA); GO_0071260 (EC: IEP, PMID: 19593445); GO_0071316 (EC: IDA, PMID: 18676776); GO_0071396 (EC: IEA); GO_0071456 (EC: IEP); GO_0090200 (EC: IMP, PMID: 17289999); GO_0097190 (EC: TAS); GO_0097191 (EC: IMP, PMID: 18852119); GO_0097192 (EC: IEA); GO_0097193 (EC: IMP, PMID: 18676776); GO_0097193 (EC: TAS); GO_0097202 (EC: IDA, PMID: 18387192); GO_1900740 (EC: TAS); GO_1901216 (EC: IEA); GO_2000078 (EC: ISS); GO_2001244 (EC: TAS) PMID: 7834748; 8929531; 8929532; 9130713; 9305851; 9369453; 9381178; 9388232; 9389483; 9463381; 9651683; 9824152; 9878060; 9973195; 10195903; 10381646; 10407019; 10521512; 10558990; 10579309; 10611223; 10620799; 10811615; 10837486; 10837489; 10880354; 10949025; 10949026; 11077446; 11206074; 11278245; 11410287; 11483855; 11494146; 11500364; 11544290; 11583631; 11689886; 11697890; 11717309; 11739707; 11742726; 11781193; 11839683; 11878929; 11908866; 11994280; 12084714; 12087097; 12115603; 12137781; 12239175; 12376548; 12477932; 12657644; 12754297; 12787561; 12842996; 12897128; 12931191; 12954615; 12965220; 14702039; 14767529; 14967141; 15033904; 15078178; 15131699; 15183529; 15226424; 15231831; 15280438; 15489334; 15574335; 15694340; 15705582; 15721256; 15731037; 15751984; 15767261; 15784622; 15849194; 15901741; 15978696; 15990872; 15998799; 16148027; 16189514; 16297499; 16403219; 16413544; 16445909; 16484005; 16603546; 16697956; 16710454; 16728406; 16767165; 16785131; 16843435; 16847055; 16908594; 16932738; 16949642; 16978419; 17011751; 17110373; 17270021; 17274640; 17287851; 17289999; 17393317; 17404594; 17420275; 17438366; 17446862; 17457084; 17474147; 17499381; 17541305; 17544220; 17557568; 17670745; 17696955; 17696989; 17900801; 17927446; 17979178; 18006502; 18029348; 18165867; 18246127; 18276761; 18309324; 18387192; 18391004; 18402774; 18402937; 18420586; 18449891; 18508762; 18508827; 18568448; 18593990; 18628207; 18636124; 18651163; 18651222; 18676776; 18775810; 18798227; 18832722; 18852119; 18973553; 19168699; 19171933; 19508210; 19587239; 19593445; 19624871; 19641507; 19667065; 19679565; 19730683; 19773546; 19882362; 19895838; 19913121; 20012528; 20043968; 20339252; 20596645; 20618440; 20628086; 20647330; 20691103; 20700721; 20810912; 20855536; 20877624; 20936779; 21076048; 21081150; 21187157; 21302807; 21317286; 21419810; 21444773; 21674599; 21849418; 21900206; 21918885; 21988832; 22011203; 22057915; 22096607; 22172950; 22214866; 22423221; 22464442; 22805310; 22837380; 23135712; 23383273; 23547889; 24255178 BCL2-associated agonist of cell death Ensembl:ENSG00000002330 HGNC:936 HPRD:04409 MIM:603167 Vega:OTTHUMG00000134302 BAD Bin Zhao, Yue Liu, Oliver He BAG-1 HAP RAP46 WEB: http://www.ncbi.nlm.nih.gov/gene BAG1 BCL2-associated athanogene 573 RP11-326F20.2 9p12 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0005057 (EC: TAS, PMID: 8947043); GO_0005515 (EC: IPI, PMID: 19800331); GO_0005634 (EC: IDA); GO_0005737 (EC: IEA); GO_0006915 (EC: IEA); GO_0007166 (EC: TAS, PMID: 8947043); GO_0035556 (EC: TAS, PMID: 8947043); GO_0043066 (EC: TAS, PMID: 8947043); GO_0051087 (EC: IEA); GO_0070389 (EC: IDA, PMID: 12853476) PMID: 7834747; 8125298; 8524784; 8692945; 8812483; 8889548; 8947043; 9305631; 9396724; 9565586; 9582267; 9603979; 9642262; 9679980; 9747877; 9774640; 9873016; 10467399; 10477749; 10671488; 10816573; 10967105; 11076863; 11101523; 11222862; 11231577; 11256614; 11257006; 11278763; 11340068; 11520069; 11676916; 11741305; 11994280; 12049201; 12297498; 12402153; 12421809; 12477932; 12724406; 12845674; 12853476; 12874020; 14517289; 14532969; 14680805; 14702039; 14978028; 15075668; 15169918; 15199607; 15297164; 15309313; 15489334; 15489336; 15538384; 15603737; 15707960; 15831476; 15843891; 15986447; 16042572; 16207813; 16292491; 16381901; 16398049; 16457154; 16482527; 17278878; 17549665; 17657847; 17662274; 17693608; 17700523; 17950682; 17954934; 18029348; 18204076; 18388150; 18413740; 18430249; 18523358; 18684711; 18805052; 18822299; 19060904; 19066611; 19151744; 19229298; 19243896; 19293798; 19317853; 19546472; 19595997; 19778524; 19800331; 19881545; 19913121; 20096920; 20156966; 20237496; 20404511; 20409521; 20628086; 20675402; 20819778; 20855536; 20858459; 21036726; 21157029; 21195059; 21522149; 21809033; 21890473; 21986497; 21988832; 22016818; 22179630; 22439756; 22454210; 22863883; 22939115; 22939629; 23000965; 23049684; 23059827; 23108401; 23178238; 23271418; 23322525; 23493285; 23553841; 23708800; 23852223; 24250222; 24318877 BCL2-associated athanogene Ensembl:ENSG00000107262 HGNC:937 HPRD:03292 MIM:601497 Vega:OTTHUMG00000019766 BAG1 Bin Zhao, Yue Liu, Oliver He BCL2L4 WEB: http://www.ncbi.nlm.nih.gov/gene BAX BCL2-associated X protein 581 19q13.3-q13.4 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0001101 (EC: IEA); GO_0001541 (EC: IEA); GO_0001764 (EC: IEA); GO_0001777 (EC: IEA); GO_0001782 (EC: IEA); GO_0001783 (EC: IDA, PMID: 15214043); GO_0001822 (EC: IEA); GO_0001836 (EC: IDA, PMID: 16199525); GO_0001844 (EC: IEA); GO_0001974 (EC: IEA); GO_0002262 (EC: IEA); GO_0002352 (EC: IEA); GO_0002358 (EC: IEA); GO_0002904 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10753914); GO_0005634 (EC: IMP, PMID: 15102863); GO_0005739 (EC: IDA, PMID: 11912183); GO_0005741 (EC: IBA); GO_0005741 (EC: TAS); GO_0005757 (EC: IDA, PMID: 9843949); GO_0005783 (EC: IDA, PMID: 16424160); GO_0005789 (EC: IDA, PMID: 16424160); GO_0005829 (EC: IDA, PMID: 11912183); GO_0005829 (EC: TAS); GO_0006687 (EC: IEA); GO_0006808 (EC: IEA); GO_0006915 (EC: NAS, PMID: 9920818); GO_0006915 (EC: TAS); GO_0006919 (EC: IDA, PMID: 11912183); GO_0006919 (EC: IMP, PMID: 11350920); GO_0006927 (EC: IMP, PMID: 10739008); GO_0007281 (EC: IEA); GO_0008053 (EC: IDA, PMID: 14769861); GO_0008289 (EC: IDA, PMID: 14522999); GO_0008625 (EC: IC, PMID: 16199525); GO_0008630 (EC: IBA); GO_0008635 (EC: IDA, PMID: 15214043); GO_0008637 (EC: IDA, PMID: 9843949); GO_0009566 (EC: IEA); GO_0009636 (EC: IDA, PMID: 16307838); GO_0009651 (EC: IEA); GO_0010248 (EC: IDA, PMID: 9843949); GO_0010332 (EC: IEA); GO_0015267 (EC: IDA, PMID: 9219694); GO_0016032 (EC: IEA); GO_0021854 (EC: IEA); GO_0021987 (EC: IEA); GO_0030264 (EC: IEA); GO_0032091 (EC: IDA, PMID: 9388232); GO_0032461 (EC: IDA, PMID: 19805544); GO_0032469 (EC: TAS, PMID: 18309324); GO_0032471 (EC: IEA); GO_0032976 (EC: IDA, PMID: 9843949); GO_0033137 (EC: IEA); GO_0033599 (EC: IEA); GO_0034644 (EC: IEA); GO_0035234 (EC: IEA); GO_0042475 (EC: IEA); GO_0042802 (EC: IPI, PMID: 10620504); GO_0042803 (EC: IDA, PMID: 16608847); GO_0042803 (EC: IPI, PMID: 9111042); GO_0043065 (EC: IMP, PMID: 17289999); GO_0043496 (EC: IDA, PMID: 9111042); GO_0043497 (EC: IPI, PMID: 9111042); GO_0043524 (EC: IEA); GO_0043525 (EC: IDA, PMID: 15637643); GO_0043653 (EC: IDA, PMID: 12499352); GO_0045136 (EC: IEA); GO_0046666 (EC: IEA); GO_0046930 (EC: IDA, PMID: 9219694); GO_0046982 (EC: IPI, PMID: 9111042); GO_0048087 (EC: IEA); GO_0048147 (EC: IEA); GO_0048515 (EC: IEA); GO_0048597 (EC: IEA); GO_0048678 (EC: IEA); GO_0048873 (EC: IEA); GO_0051259 (EC: IDA, PMID: 19074440); GO_0051260 (EC: IDA, PMID: 14522999); GO_0051281 (EC: IEA); GO_0051402 (EC: IEA); GO_0051434 (EC: IDA); GO_0051434 (EC: IPI, PMID: 15705586); GO_0051726 (EC: IEA); GO_0051881 (EC: IDA, PMID: 9843949); GO_0060011 (EC: IEA); GO_0060041 (EC: IEA); GO_0060058 (EC: IEA); GO_0060068 (EC: IEA); GO_0070059 (EC: IMP, PMID: 16645094); GO_0070062 (EC: IDA); GO_0070242 (EC: IEA); GO_0071310 (EC: IEA); GO_0072332 (EC: IEA); GO_0090200 (EC: IDA, PMID: 14963330); GO_0097136 (EC: IDA); GO_0097144 (EC: IDA, PMID: 19767770); GO_0097190 (EC: IDA, PMID: 16424160); GO_0097191 (EC: IDA, PMID: 15214043); GO_0097192 (EC: IBA); GO_0097193 (EC: IDA, PMID: 16462759); GO_0097193 (EC: TAS); GO_0097296 (EC: IEA); GO_1900103 (EC: IMP, PMID: 16645094); GO_1901030 (EC: TAS); GO_1902262 (EC: IEA); GO_1902263 (EC: IEA); GO_1902512 (EC: IMP, PMID: 11350920); GO_1990009 (EC: IMP, PMID: 10702418); GO_1990117 (EC: IDA, PMID: 15214043); GO_2001234 (EC: IEA); GO_2001241 (EC: IEA); GO_2001244 (EC: IMP, PMID: 14963330) PMID: 7566098; 7607685; 7834749; 8358790; 8521816; 8580080; 8760290; 8889548; 8961277; 9020077; 9027312; 9111042; 9130713; 9153240; 9219694; 9372935; 9388232; 9449720; 9463381; 9531611; 9565621; 9742125; 9748162; 9824152; 9843949; 9920818; 9988273; 10200447; 10365962; 10381646; 10437917; 10620504; 10620603; 10620799; 10629050; 10702418; 10716992; 10739008; 10753914; 10772918; 10837489; 10854321; 10908576; 10942389; 11060313; 11106734; 11136736; 11161816; 11175251; 11175336; 11251969; 11259440; 11278245; 11283018; 11350920; 11437653; 11571294; 11574543; 11602639; 11642719; 11742726; 11759059; 11759062; 11782443; 11787859; 11839668; 11839683; 11842081; 11850803; 11850816; 11852106; 11867266; 11869962; 11875499; 11894116; 11899739; 11909872; 11911971; 11912124; 11912183; 11922616; 11929871; 11932420; 11943780; 11949842; 11992551; 11994280; 11997495; 12023951; 12025227; 12032841; 12036888; 12058280; 12070030; 12070120; 12082629; 12137781; 12151395; 12161031; 12165421; 12169275; 12176904; 12189556; 12193163; 12214154; 12215338; 12215842; 12270344; 12359369; 12388688; 12389125; 12393866; 12393884; 12408758; 12419244; 12426317; 12439925; 12445631; 12454021; 12477729; 12477932; 12481899; 12490315; 12496485; 12499352; 12510156; 12575534; 12579342; 12583439; 12592374; 12606781; 12732850; 12737446; 12743423; 12749011; 12767928; 12782632; 12808108; 12816867; 12837286; 12839682; 12853473; 12901880; 12907654; 12917444; 12963997; 12970744; 14522999; 14550297; 14559989; 14596892; 14606101; 14612448; 14612938; 14628086; 14631373; 14634023; 14647416; 14647455; 14661970; 14681224; 14698203; 14704000; 14714449; 14716828; 14719078; 14730312; 14752512; 14766748; 14767525; 14769861; 14963330; 14971737; 14980220; 15024076; 15033690; 15037603; 15073604; 15077116; 15096513; 15102863; 15131699; 15148411; 15149158; 15158440; 15214043; 15231068; 15254227; 15258908; 15262986; 15292938; 15298965; 15302859; 15304079; 15314639; 15322047; 15351796; 15375594; 15375604; 15383280; 15388581; 15459197; 15467752; 15484294; 15489334; 15516208; 15555592; 15574335; 15607964; 15613549; 15637055; 15637643; 15638363; 15642728; 15655830; 15657356; 15688029; 15694358; 15705586; 15710329; 15735127; 15735709; 15743033; 15743760; 15757910; 15764647; 15767261; 15770735; 15773546; 15782132; 15806163; 15830715; 15832769; 15843890; 15846375; 15889622; 15893728; 15901672; 15949439; 15962362; 16009130; 16010425; 16085058; 16113678; 16132718; 16139338; 16148027; 16151013; 16172114; 16172118; 16186627; 16199525; 16215676; 16229013; 16235026; 16246184; 16307023; 16307838; 16344548; 16380996; 16410245; 16424160; 16436379; 16443387; 16462759; 16472763; 16479009; 16485142; 16518869; 16538501; 16552754; 16568093; 16572399; 16575548; 16603637; 16608847; 16611260; 16642033; 16645094; 16709574; 16810067; 16830365; 16832704; 16855163; 16874066; 16946732; 16949642; 16987815; 17007374; 17015472; 17015762; 17052454; 17067385; 17074758; 17084966; 17091766; 17097560; 17107772; 17118768; 17140287; 17171827; 17203183; 17203211; 17213822; 17235284; 17274640; 17289842; 17289999; 17335847; 17346710; 17388661; 17390059; 17395004; 17404017; 17426704; 17438366; 17438390; 17486058; 17494694; 17496930; 17499214; 17509221; 17513609; 17519046; 17525161; 17534116; 17535899; 17556360; 17562177; 17575222; 17626754; 17634542; 17635522; 17635912; 17643375; 17666167; 17668322; 17676485; 17686764; 17693666; 17803695; 17823127; 17855051; 17880809; 17897954; 17900801; 17905238; 17911107; 17912641; 17927446; 17927572; 17978676; 17981213; 17990907; 17993285; 17996028; 17997990; 18006502; 18006817; 18006836; 18019411; 18023359; 18029348; 18034190; 18054155; 18059532; 18074738; 18089567; 18158779; 18160666; 18177350; 18178565; 18193434; 18195012; 18211414; 18214681; 18223689; 18240345; 18251703; 18258596; 18259190; 18259191; 18282575; 18299320; 18299329; 18307410; 18309324; 18331646; 18344566; 18362350; 18362892; 18375382; 18390829; 18395515; 18415681; 18415689; 18445700; 18449500; 18453545; 18454316; 18462830; 18472156; 18472157; 18474606; 18481805; 18494554; 18508723; 18511705; 18534994; 18546202; 18563851; 18568448; 18590739; 18590778; 18594472; 18636124; 18642056; 18644472; 18651163; 18651223; 18664350; 18665919; 18670882; 18676372; 18676680; 18692524; 18695676; 18705408; 18705844; 18718060; 18719392; 18727869; 18772168; 18793611; 18812638; 18813857; 18814044; 18818203; 18818304; 18835031; 18840646; 18925695; 18928586; 18928588; 18936968; 18941118; 18948948; 18973553; 18974096; 18979557; 19031258; 19035131; 19054058; 19056676; 19062087; 19074440; 19074885; 19101510; 19118032; 19125733; 19141860; 19148187; 19150424; 19157504; 19170196; 19177010; 19196429; 19221769; 19228953; 19237173; 19247369; 19265193; 19266703; 19278624; 19319745; 19336552; 19351510; 19360919; 19363595; 19376889; 19380879; 19429011; 19439449; 19439472; 19453261; 19463775; 19475409; 19481066; 19494020; 19541585; 19564333; 19573080; 19587033; 19625176; 19629483; 19636580; 19655415; 19657228; 19660860; 19680558; 19692168; 19692349; 19700502; 19723045; 19729672; 19737817; 19745831; 19767770; 19773279; 19801665; 19805544; 19809877; 19812265; 19846939; 19875445; 19880508; 19888426; 19895710; 19898928; 19913121; 19931389; 19937732; 19938958; 19955813; 19956635; 19968986; 20015862; 20034877; 20045442; 20075864; 20101465; 20114030; 20130137; 20140092; 20180421; 20200776; 20300062; 20308427; 20333643; 20340172; 20346360; 20360684; 20382739; 20404718; 20416158; 20423844; 20431057; 20453000; 20485298; 20490654; 20503275; 20561923; 20565851; 20584903; 20627094; 20628086; 20644561; 20652449; 20683843; 20683914; 20723294; 20723427; 20728382; 20732674; 20803149; 20819778; 20822926; 20850011; 20855536; 20877624; 20929130; 20929131; 20942963; 20959405; 20960177; 20966963; 21029589; 21041309; 21042904; 21048031; 21060336; 21067292; 21069436; 21070973; 21090097; 21104343; 21115898; 21122152; 21123558; 21138867; 21139048; 21148306; 21156403; 21159883; 21173168; 21196320; 21199865; 21223758; 21245196; 21289292; 21367852; 21414921; 21458670; 21483469; 21506333; 21521785; 21530645; 21565982; 21567405; 21597469; 21606679; 21642427; 21642428; 21674599; 21695182; 21706237; 21712378; 21717192; 21725926; 21729540; 21746927; 21751259; 21752397; 21778226; 21785112; 21810274; 21819468; 21847364; 21852238; 21861179; 21862870; 21883444; 21887277; 21890473; 21903925; 21906983; 21907236; 21936009; 21947543; 21949851; 21952639; 21953454; 21978892; 22014978; 22015607; 22037145; 22052011; 22053931; 22056880; 22065578; 22067154; 22072718; 22109662; 22141411; 22159712; 22189282; 22198199; 22201672; 22246181; 22262057; 22277657; 22278385; 22292626; 22297694; 22309278; 22366766; 22418443; 22440942; 22442678; 22479585; 22484496; 22524261; 22526391; 22544745; 22552851; 22560721; 22570867; 22590594; 22629415; 22645134; 22668011; 22675938; 22685558; 22707322; 22710714; 22719244; 22729748; 22732402; 22736223; 22745744; 22748563; 22761420; 22785534; 22852863; 22860893; 22892098; 22906710; 22910913; 22926545; 22949938; 22995373; 23000965; 23038985; 23049480; 23064052; 23088735; 23140172; 23151078; 23151600; 23170075; 23213219; 23220614; 23245210; 23283967; 23289213; 23291169; 23295106; 23297497; 23324193; 23329846; 23334076; 23383273; 23389372; 23392123; 23421021; 23421973; 23442864; 23479508; 23479509; 23487455; 23543151; 23553948; 23562578; 23658815; 23682076; 23744079; 23777485; 23788040; 23824909; 23900080; 23900644; 23907458; 23907941; 23908591; 23966164; 24055994; 24074954; 24100034; 24113173; 24161344; 24200861; 24379070 BCL2-associated X protein Ensembl:ENSG00000087088 HGNC:959 HPRD:02498 MIM:600040 Vega:OTTHUMG00000160476 BAX Bin Zhao, Yue Liu, Oliver He CHE1 CHE2 E1 WEB: http://www.ncbi.nlm.nih.gov/gene BCHE butyrylcholinesterase 590 3q26.1-q26.2 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0001540 (EC: NAS, PMID: 11569538); GO_0003824 (EC: NAS, PMID: 11569538); GO_0003990 (EC: IBA); GO_0003990 (EC: ISS); GO_0004104 (EC: IDA, PMID: 19452557); GO_0005576 (EC: NAS, PMID: 14718574); GO_0005576 (EC: TAS); GO_0005615 (EC: IBA); GO_0005641 (EC: IEA); GO_0005788 (EC: IBA); GO_0007271 (EC: IBA); GO_0007612 (EC: IEA); GO_0008285 (EC: IEA); GO_0014016 (EC: IEA); GO_0016020 (EC: IEA); GO_0019695 (EC: IBA); GO_0019899 (EC: NAS, PMID: 11569538); GO_0033265 (EC: IEA); GO_0042493 (EC: IEA); GO_0042802 (EC: IPI); GO_0043279 (EC: IEA); GO_0044267 (EC: TAS); GO_0050783 (EC: TAS, PMID: 8622553); GO_0050805 (EC: IEA); GO_0051384 (EC: IEA); GO_0051593 (EC: IEA); GO_0072562 (EC: IDA) PMID: 1769657; 1769658; 2318303; 2322535; 2339692; 2915989; 3035536; 3067729; 3115973; 3477799; 3542989; 8063698; 8622553; 8680411; 8930175; 9543549; 9673783; 10529218; 11125748; 11436125; 11569538; 11725818; 11738493; 11749053; 11793025; 11848688; 11849755; 11856322; 11856351; 12003252; 12009429; 12044901; 12074828; 12130740; 12387584; 12417112; 12477932; 12668920; 12687586; 12724618; 12811800; 12869558; 12881446; 12901493; 14622273; 14686935; 14718574; 14735258; 14760718; 15060281; 15111428; 15258737; 15386241; 15449725; 15465921; 15489334; 15519745; 15690550; 15696543; 15731585; 15781196; 15802910; 15834019; 15907830; 16020944; 16105444; 16213467; 16278840; 16288482; 16289064; 16298355; 16335952; 16344560; 16429499; 16504521; 16731619; 16788378; 16801396; 16824336; 16909200; 16962996; 16973370; 17116317; 17192624; 17275003; 17318303; 17335779; 17350607; 17410321; 17503475; 17660298; 17690023; 17698511; 17700357; 17701416; 17768338; 17852836; 17917325; 17923322; 17996334; 18075469; 18076380; 18165570; 18237553; 18290843; 18300943; 18322399; 18334913; 18422653; 18457821; 18550040; 18555211; 18640242; 18778798; 18780301; 19006190; 19010318; 19019080; 19056482; 19156168; 19217865; 19383604; 19452557; 19474452; 19481150; 19578796; 19617863; 19685167; 19713000; 19913121; 19956635; 20056567; 20058037; 20122907; 20143968; 20193849; 20308990; 20356562; 20379614; 20399202; 20445134; 20529763; 20538374; 20628086; 20644562; 20677742; 20807286; 20879632; 20883446; 20886866; 21029050; 21402063; 21454498; 21473860; 21493754; 21530486; 21547979; 21576115; 21862451; 21943158; 22040426; 22157615; 22294139; 22331678; 22402324; 22560633; 22750491; 22778864; 22901043; 22917637; 22922115; 22935510; 23000450; 23022600; 23044488; 23063927; 23092211; 23123771; 23419831; 23466605; 23508960; 23689009; 23782236; 24001779; 24125115 butyrylcholinesterase Ensembl:ENSG00000114200 HGNC:983 HPRD:01519 MIM:177400 Vega:OTTHUMG00000158131 BCHE Bin Zhao, Yue Liu, Oliver He BCL1 D11S287E PRAD1 U21B31 WEB: http://www.ncbi.nlm.nih.gov/gene CCND1 cyclin D1 595 11q13 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0000082 (EC: IDA, PMID: 19412162); GO_0000082 (EC: TAS, PMID: 18483258); GO_0000122 (EC: IDA, PMID: 16569215); GO_0000278 (EC: TAS); GO_0000307 (EC: IDA, PMID: 17420273); GO_0000320 (EC: IEA); GO_0001889 (EC: IEA); GO_0001934 (EC: IDA, PMID: 8114739); GO_0003714 (EC: IDA, PMID: 16569215); GO_0004672 (EC: IEA); GO_0005515 (EC: IPI, PMID: 15232106); GO_0005622 (EC: IDA); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005829 (EC: TAS); GO_0005923 (EC: IEA); GO_0006351 (EC: IEA); GO_0006974 (EC: IDA, PMID: 19412162); GO_0007219 (EC: TAS); GO_0007595 (EC: IEA); GO_0008134 (EC: IPI, PMID: 16569215); GO_0010039 (EC: IEA); GO_0010165 (EC: IEA); GO_0010243 (EC: IEA); GO_0010971 (EC: IDA, PMID: 19124461); GO_0016020 (EC: IEA); GO_0016538 (EC: IEA); GO_0017053 (EC: IDA, PMID: 16569215); GO_0019899 (EC: IPI, PMID: 19412162); GO_0019901 (EC: IPI, PMID: 19124461); GO_0030178 (EC: IEA); GO_0030857 (EC: IEA); GO_0030968 (EC: IEA); GO_0031100 (EC: IEA); GO_0031571 (EC: IDA, PMID: 19412162); GO_0032026 (EC: IEA); GO_0032403 (EC: IEA); GO_0033197 (EC: IEA); GO_0033327 (EC: IEA); GO_0033598 (EC: IEA); GO_0033601 (EC: IEA); GO_0042493 (EC: IEP, PMID: 18291362); GO_0042826 (EC: IPI, PMID: 18417529); GO_0043627 (EC: IEA); GO_0045444 (EC: IEA); GO_0045471 (EC: IEA); GO_0045737 (EC: IDA, PMID: 8114739); GO_0051301 (EC: IEA); GO_0051412 (EC: IEA); GO_0051592 (EC: IEA); GO_0060070 (EC: IEA); GO_0060749 (EC: IEA); GO_0070064 (EC: IDA, PMID: 19124461); GO_0070141 (EC: IDA, PMID: 18483258); GO_0071157 (EC: IDA, PMID: 19124461) PMID: 1386335; 1532244; 1535701; 1682919; 1826542; 1827756; 1833066; 1833629; 6610211; 7478582; 7568034; 7665234; 7687458; 7733934; 7739547; 7903056; 7908906; 8058338; 8058751; 8101826; 8114739; 8134134; 8136159; 8159685; 8204893; 8208539; 8259215; 8302605; 8490963; 8643455; 8647086; 8657154; 8662825; 8756624; 8826947; 8867812; 8887674; 8978686; 8999999; 9003781; 9039267; 9050835; 9106657; 9139732; 9150368; 9178893; 9190208; 9228064; 9244350; 9311993; 9372967; 9380698; 9426067; 9626345; 9632134; 9661876; 9736735; 9832502; 9832503; 9837900; 9926939; 10066798; 10202152; 10318892; 10344732; 10353443; 10371345; 10486249; 10491434; 10500095; 10580009; 10581175; 10645009; 10764802; 10766840; 10801854; 10850422; 10908655; 10910956; 10952989; 11042687; 11073968; 11076863; 11126356; 11256614; 11279133; 11311237; 11360184; 11470749; 11593423; 11642719; 11696452; 11698342; 11698641; 11739785; 11739795; 11751903; 11788592; 11793365; 11805292; 11813305; 11815623; 11836555; 11838966; 11860939; 11870667; 11872630; 11884610; 11896626; 11902820; 11923474; 11935308; 11940657; 11948404; 11958128; 11986316; 11992406; 12002755; 12006580; 12007188; 12024041; 12036888; 12036906; 12036934; 12036951; 12048199; 12067972; 12096344; 12097293; 12101670; 12127555; 12138206; 12150453; 12151312; 12164325; 12203362; 12209953; 12231535; 12237776; 12241561; 12364325; 12376514; 12379776; 12383116; 12388769; 12391146; 12394763; 12439750; 12444551; 12455063; 12477932; 12480939; 12515730; 12519773; 12529437; 12539042; 12554669; 12557224; 12569141; 12582032; 12589056; 12594215; 12601350; 12606305; 12607604; 12634633; 12673692; 12676926; 12680219; 12692418; 12694349; 12707028; 12738746; 12743597; 12746453; 12759391; 12761882; 12778072; 12807740; 12808109; 12824903; 12825853; 12867429; 12883688; 12883749; 12894561; 12896908; 12899785; 12914697; 12917336; 12917338; 12921950; 12930597; 12937137; 12955092; 12965081; 12972956; 14530270; 14612904; 14641107; 14645506; 14645576; 14646596; 14657069; 14666635; 14666673; 14666699; 14679024; 14688016; 14689059; 14701845; 14703063; 14720512; 14754892; 14759115; 14764597; 14767060; 14966901; 14981950; 15059606; 15060836; 15063389; 15090460; 15128059; 15133490; 15138714; 15153436; 15172998; 15203873; 15225161; 15226187; 15232106; 15239347; 15245939; 15277517; 15282324; 15297421; 15350626; 15355984; 15375804; 15377668; 15378006; 15485920; 15489334; 15489336; 15498584; 15505422; 15513923; 15538282; 15539430; 15544931; 15545188; 15551329; 15557280; 15557752; 15558026; 15578074; 15580291; 15592430; 15621754; 15652748; 15655836; 15659654; 15668481; 15684604; 15688030; 15695117; 15695403; 15709184; 15713663; 15734847; 15735724; 15754315; 15755896; 15776189; 15791567; 15808510; 15809880; 15811121; 15824172; 15845652; 15856299; 15861516; 15862753; 15863141; 15870300; 15878868; 15893730; 15896460; 15897899; 15900590; 15914210; 15923181; 15943036; 15949570; 15950906; 15951302; 15951563; 15971196; 15981100; 16051426; 16061635; 16082198; 16115225; 16123218; 16131791; 16142313; 16155412; 16163549; 16163738; 16166625; 16172916; 16174239; 16207592; 16226824; 16258726; 16258756; 16273238; 16287839; 16322291; 16328437; 16334487; 16341674; 16343742; 16357142; 16381901; 16399423; 16406195; 16407831; 16436505; 16461912; 16488657; 16490596; 16495921; 16507767; 16508013; 16547504; 16552496; 16568089; 16569215; 16600870; 16601140; 16614707; 16614728; 16616093; 16638786; 16644723; 16645724; 16672066; 16690963; 16691558; 16691626; 16699726; 16705174; 16723714; 16732330; 16758952; 16776827; 16782892; 16783567; 16788380; 16804724; 16815198; 16820873; 16829689; 16832876; 16843438; 16860316; 16865250; 16870553; 16884382; 16912209; 16916940; 16924241; 16940298; 16942622; 16959222; 16980615; 16985050; 17011980; 17018901; 17022831; 17046823; 17053782; 17060721; 17067457; 17070615; 17080657; 17081987; 17090192; 17106256; 17116943; 17129455; 17139501; 17188136; 17198740; 17203162; 17203214; 17205132; 17207971; 17208333; 17240151; 17254966; 17274640; 17278098; 17284370; 17299095; 17308274; 17310991; 17316413; 17334399; 17344214; 17374178; 17393422; 17398034; 17409409; 17420273; 17427198; 17437044; 17438373; 17447856; 17482347; 17486065; 17499716; 17509221; 17517369; 17517622; 17524364; 17525627; 17549378; 17556661; 17561354; 17600882; 17605237; 17606477; 17606765; 17607588; 17616526; 17616699; 17626745; 17629555; 17634024; 17653856; 17684142; 17693985; 17695500; 17698033; 17720094; 17724472; 17804732; 17848143; 17855508; 17868090; 17881732; 17882269; 17901853; 17906980; 17908995; 17912028; 17916995; 17922974; 17923265; 17927591; 17927853; 17934069; 17935714; 17941827; 17960397; 18006686; 18006821; 18019405; 18024283; 18027856; 18043898; 18047954; 18056951; 18061526; 18063576; 18067636; 18079202; 18171527; 18174243; 18180298; 18182398; 18187454; 18194492; 18194538; 18196581; 18197291; 18205772; 18212742; 18226366; 18237245; 18239461; 18240019; 18251939; 18281541; 18284543; 18291362; 18301453; 18306932; 18327210; 18327303; 18341653; 18343791; 18347178; 18349267; 18349392; 18355450; 18355918; 18358634; 18361427; 18367547; 18373498; 18379871; 18381935; 18393977; 18398822; 18404250; 18406353; 18413612; 18413728; 18413773; 18413827; 18417529; 18431519; 18437417; 18445313; 18456656; 18459109; 18467434; 18483258; 18483394; 18484097; 18491248; 18507837; 18514338; 18537972; 18547262; 18548202; 18562319; 18598945; 18604165; 18609126; 18616527; 18618300; 18625744; 18632615; 18640142; 18644870; 18650423; 18665038; 18665077; 18676680; 18677114; 18695042; 18695676; 18703151; 18710938; 18710949; 18713830; 18715616; 18715870; 18753363; 18758380; 18769147; 18787961; 18794045; 18794151; 18798551; 18799029; 18819000; 18822177; 18823025; 18829570; 18839518; 18842998; 18843022; 18844221; 18925698; 18936968; 18942117; 18942709; 18949380; 18950845; 18983468; 18988190; 18991334; 19009649; 19020753; 19034659; 19040567; 19047108; 19055446; 19064572; 19070887; 19071090; 19074853; 19074885; 19075005; 19080374; 19084934; 19086036; 19091404; 19096232; 19106611; 19106744; 19116388; 19124461; 19124506; 19129688; 19134409; 19136653; 19139013; 19142864; 19143767; 19147768; 19152247; 19166930; 19170196; 19183483; 19187116; 19203829; 19237565; 19242061; 19258477; 19287456; 19289374; 19302219; 19303206; 19321861; 19322201; 19324500; 19330026; 19336552; 19373442; 19375306; 19379556; 19386349; 19412162; 19415719; 19430707; 19440933; 19443866; 19448414; 19453261; 19467018; 19470470; 19470724; 19474518; 19475398; 19477949; 19489683; 19499154; 19502783; 19505905; 19525979; 19536092; 19538740; 19549773; 19550124; 19554511; 19556892; 19558863; 19564413; 19572978; 19573080; 19575018; 19578796; 19585495; 19589865; 19602458; 19625176; 19633425; 19634112; 19636701; 19638577; 19666237; 19666944; 19670700; 19679881; 19687314; 19690970; 19692168; 19706803; 19723065; 19724860; 19728335; 19738611; 19750108; 19757306; 19760977; 19773279; 19774638; 19779113; 19780858; 19787783; 19789190; 19795398; 19800042; 19801633; 19801969; 19802676; 19806481; 19821490; 19822419; 19823025; 19823825; 19826048; 19850937; 19883431; 19885547; 19898427; 19900369; 19903334; 19904758; 19915615; 19915977; 19917254; 19919588; 19921577; 19923826; 19933579; 19935879; 19940156; 19941161; 19956635; 19956831; 19967453; 20028857; 20062011; 20067552; 20072652; 20087644; 20101207; 20103831; 20113529; 20137349; 20154722; 20160059; 20172376; 20179208; 20181625; 20204303; 20204402; 20231315; 20232305; 20301636; 20304954; 20306448; 20338923; 20347627; 20359085; 20359118; 20372799; 20373052; 20380574; 20389301; 20392877; 20397048; 20401451; 20404095; 20407865; 20418097; 20426528; 20429623; 20437058; 20443083; 20453000; 20453838; 20459741; 20460515; 20466633; 20473525; 20484017; 20485284; 20503270; 20512928; 20515940; 20540739; 20543468; 20564361; 20575692; 20577923; 20578819; 20581865; 20586028; 20616110; 20618968; 20628002; 20631636; 20631637; 20631638; 20644561; 20662834; 20680537; 20680693; 20683026; 20683061; 20683643; 20699365; 20701069; 20714998; 20723296; 20727381; 20737317; 20801098; 20809334; 20822933; 20837141; 20839920; 20844743; 20856207; 20857402; 20890425; 20924203; 20950152; 20951943; 20971731; 21036743; 21042715; 21044962; 21056029; 21062395; 21079973; 21098327; 21107342; 21116504; 21131888; 21135252; 21139048; 21148318; 21159451; 21161398; 21179427; 21185249; 21187402; 21193919; 21200149; 21212260; 21242960; 21242966; 21254295; 21268129; 21273603; 21281227; 21300445; 21315112; 21315488; 21326383; 21327470; 21331989; 21343394; 21347341; 21385053; 21401699; 21410931; 21438905; 21447152; 21454057; 21455311; 21487939; 21492065; 21497295; 21498736; 21503589; 21517236; 21526487; 21537090; 21537837; 21544737; 21547408; 21548803; 21569306; 21594903; 21606015; 21654808; 21738001; 21745168; 21746927; 21777578; 21778791; 21783402; 21789902; 21799732; 21830375; 21850541; 21867613; 21890746; 21892090; 21906983; 21912938; 21946890; 21952639; 21955753; 21956468; 21963094; 21965784; 21972713; 21987572; 21988832; 21989330; 21989926; 22002566; 22024187; 22037875; 22050898; 22052559; 22065993; 22072615; 22100494; 22102309; 22133292; 22135025; 22150974; 22158041; 22204713; 22231956; 22234583; 22260073; 22261253; 22266466; 22289525; 22296356; 22304571; 22306268; 22307325; 22318732; 22321253; 22322158; 22336657; 22357515; 22369110; 22387541; 22391566; 22399638; 22406359; 22406644; 22451658; 22456513; 22460364; 22467101; 22467868; 22475046; 22484283; 22490843; 22528945; 22534667; 22553812; 22565393; 22581837; 22590809; 22606291; 22629227; 22640743; 22647349; 22647378; 22706868; 22707287; 22711989; 22722256; 22747683; 22760121; 22770229; 22776845; 22790016; 22801439; 22812184; 22814742; 22819905; 22833568; 22853846; 22864797; 22884659; 22884800; 22893700; 22901215; 22905217; 22905260; 22922827; 22926658; 22967707; 22976805; 22982899; 23000965; 23001925; 23020291; 23031786; 23044415; 23060014; 23108396; 23111452; 23125009; 23126531; 23135283; 23144465; 23161911; 23163571; 23201130; 23217712; 23222716; 23226276; 23244103; 23255553; 23261678; 23270726; 23292829; 23300886; 23311506; 23315417; 23322406; 23327593; 23354584; 23383003; 23383271; 23388457; 23390492; 23396251; 23400686; 23455922; 23502783; 23515614; 23525507; 23529990; 23540573; 23543735; 23562784; 23566410; 23568005; 23568006; 23613410; 23625206; 23625573; 23648671; 23653001; 23661346; 23664541; 23670132; 23674142; 23696923; 23707388; 23718855; 23720779; 23731275; 23733133; 23737530; 23741361; 23795354; 23804702; 23852369; 23861098; 23864650; 23873109; 23893383; 23897809; 23898488; 23920145; 23936312; 23949314; 23975835; 23985254; 23991960; 23991964; 24019069; 24060591; 24085301; 24088803; 24119401; 24134204; 24145651; 24282282; 24324055; 24403468 cyclin D1 Ensembl:ENSG00000110092 HGNC:1582 HPRD:01346 MIM:168461 Vega:OTTHUMG00000167877 CCND1 Bin Zhao, Yue Liu, Oliver He Bcl-2 PPP1R50 WEB: http://www.ncbi.nlm.nih.gov/gene BCL2 B-cell CLL/lymphoma 2 596 18q21.3 20140408 9606 18 protein-coding Official from a nomenclature committee GO_0000209 (EC: IDA, PMID: 16717086); GO_0001101 (EC: IEA); GO_0001503 (EC: IEA); GO_0001541 (EC: IEA); GO_0001656 (EC: IEA); GO_0001658 (EC: IEA); GO_0001662 (EC: IEA); GO_0001782 (EC: IEA); GO_0001836 (EC: ISS, PMID: 9843949); GO_0001836 (EC: NAS, PMID: 9027314); GO_0001952 (EC: IEA); GO_0002020 (EC: IDA, PMID: 10620603); GO_0002320 (EC: IEA); GO_0002326 (EC: IEA); GO_0002931 (EC: IEA); GO_0003014 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10837489); GO_0005634 (EC: IDA, PMID: 7546744); GO_0005737 (EC: IDA, PMID: 11530860); GO_0005739 (EC: IDA, PMID: 7896880); GO_0005741 (EC: IDA, PMID: 8402648); GO_0005741 (EC: TAS); GO_0005783 (EC: IDA, PMID: 8402648); GO_0005789 (EC: IEA); GO_0005829 (EC: IEA); GO_0006470 (EC: IEA); GO_0006582 (EC: IEA); GO_0006808 (EC: IEA); GO_0006915 (EC: TAS); GO_0006959 (EC: TAS, PMID: 1908951); GO_0006974 (EC: IMP, PMID: 17875758); GO_0007015 (EC: IEA); GO_0007409 (EC: IEA); GO_0007565 (EC: NAS, PMID: 11530860); GO_0007569 (EC: IEA); GO_0008134 (EC: IEA); GO_0008219 (EC: IDA, PMID: 36599); GO_0008584 (EC: IEA); GO_0008625 (EC: IDA, PMID: 10597216); GO_0008630 (EC: IBA); GO_0008631 (EC: IEA); GO_0009314 (EC: NAS, PMID: 15799693); GO_0009636 (EC: IDA, PMID: 16307838); GO_0009791 (EC: IEA); GO_0010039 (EC: IDA, PMID: 11264898); GO_0010224 (EC: IEA); GO_0010332 (EC: IEA); GO_0010507 (EC: TAS, PMID: 18309324); GO_0010523 (EC: IEA); GO_0010559 (EC: IEA); GO_0014031 (EC: IEA); GO_0014042 (EC: IEA); GO_0014911 (EC: IEA); GO_0015267 (EC: IDA, PMID: 9219694); GO_0016020 (EC: IDA, PMID: 7896880); GO_0016049 (EC: IEA); GO_0016248 (EC: IDA, PMID: 9219694); GO_0016337 (EC: IEA); GO_0018105 (EC: IEA); GO_0018107 (EC: IEA); GO_0021747 (EC: IEA); GO_0022612 (EC: IEA); GO_0022898 (EC: IDA, PMID: 9219694); GO_0030279 (EC: IEA); GO_0030307 (EC: IDA, PMID: 8022822); GO_0030308 (EC: IEA); GO_0030318 (EC: IEA); GO_0030336 (EC: IEA); GO_0030890 (EC: IMP, PMID: 17875758); GO_0031069 (EC: IEA); GO_0031103 (EC: IEA); GO_0031625 (EC: IPI); GO_0031647 (EC: IEA); GO_0031965 (EC: IDA, PMID: 1502141); GO_0032469 (EC: TAS, PMID: 18309324); GO_0032835 (EC: IEA); GO_0032848 (EC: IDA, PMID: 10506221); GO_0033033 (EC: IEA); GO_0033077 (EC: IEA); GO_0033138 (EC: IEA); GO_0033689 (EC: IEA); GO_0034097 (EC: IDA, PMID: 9184696); GO_0035094 (EC: IDA, PMID: 12421819); GO_0035265 (EC: IEA); GO_0035872 (EC: TAS); GO_0040018 (EC: IEA); GO_0042100 (EC: IDA, PMID: 1373874); GO_0042149 (EC: IEA); GO_0042493 (EC: IDA, PMID: 36599); GO_0042493 (EC: IMP, PMID: 17875758); GO_0042542 (EC: IEA); GO_0042802 (EC: IPI, PMID: 18835031); GO_0042803 (EC: IPI, PMID: 9111042); GO_0043029 (EC: IEA); GO_0043066 (EC: IDA, PMID: 10506221); GO_0043066 (EC: IMP, PMID: 17289999); GO_0043085 (EC: IEA); GO_0043209 (EC: IEA); GO_0043375 (EC: IEA); GO_0043496 (EC: IDA, PMID: 9111042); GO_0043497 (EC: IDA, PMID: 9111042); GO_0043524 (EC: IDA, PMID: 7546744); GO_0043565 (EC: IDA, PMID: 12086670); GO_0043583 (EC: IEA); GO_0045069 (EC: IEA); GO_0045087 (EC: TAS); GO_0045636 (EC: IEA); GO_0045930 (EC: IEA); GO_0046671 (EC: IEA); GO_0046902 (EC: ISS, PMID: 9843949); GO_0046930 (EC: IDA, PMID: 9219694); GO_0046982 (EC: IPI, PMID: 9111042); GO_0048041 (EC: IEA); GO_0048536 (EC: IEA); GO_0048538 (EC: IEA); GO_0048546 (EC: IEA); GO_0048589 (EC: IEA); GO_0048599 (EC: IEA); GO_0048743 (EC: IEA); GO_0048753 (EC: IEA); GO_0048873 (EC: IEA); GO_0050853 (EC: IMP, PMID: 17875758); GO_0051384 (EC: IEA); GO_0051402 (EC: TAS, PMID: 16167175); GO_0051434 (EC: IPI, PMID: 9111042); GO_0051607 (EC: IDA, PMID: 10620603); GO_0051721 (EC: IEA); GO_0051881 (EC: ISS, PMID: 9843949); GO_0051902 (EC: TAS, PMID: 9027314); GO_0051924 (EC: IDA, PMID: 8022822); GO_0055085 (EC: IDA, PMID: 9219694); GO_0070059 (EC: IDA, PMID: 15776018); GO_0071310 (EC: IEA); GO_0071456 (EC: IEA); GO_0072593 (EC: IEA); GO_0097192 (EC: IEA); GO_0097193 (EC: TAS); GO_1900740 (EC: TAS); GO_2000134 (EC: IEA); GO_2000811 (EC: IMP, PMID: 15006356); GO_2001234 (EC: IMP); GO_2001240 (EC: IGI, PMID: 8358790); GO_2001243 (EC: IDA, PMID: 11684014); GO_2001244 (EC: TAS) PMID: 36599; 1339299; 1373874; 1453000; 1502141; 1508712; 1908951; 2250705; 2834197; 2875799; 3285301; 3523487; 3924412; 7546744; 7579350; 7593193; 7650367; 7753817; 7772249; 7834748; 7896880; 7929424; 7954800; 8022822; 8050499; 8080725; 8090743; 8183370; 8232588; 8358790; 8402618; 8402648; 8551385; 8668206; 8760290; 8790371; 8910675; 8929532; 8949945; 9027314; 9031086; 9070836; 9109491; 9111042; 9115213; 9119086; 9130713; 9184696; 9219694; 9226175; 9226228; 9305631; 9334338; 9389483; 9395403; 9430630; 9449720; 9463381; 9488477; 9525867; 9561195; 9660918; 9668078; 9727491; 9731710; 9738012; 9765397; 9788433; 9843949; 9852076; 9973195; 10072505; 10075695; 10198631; 10217402; 10329560; 10330179; 10354271; 10417825; 10467396; 10490827; 10506221; 10521466; 10567572; 10597216; 10620603; 10620799; 10622714; 10625696; 10669763; 10677502; 10679027; 10716992; 10807576; 10837489; 10848600; 10871848; 10949025; 11054413; 11060313; 11123279; 11126360; 11158204; 11175251; 11181702; 11206074; 11262395; 11264898; 11278245; 11323417; 11325850; 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24157866; 24240096; 24256571; 24288815; 24293274; 24299314; 24314632; 24395794 B-cell CLL/lymphoma 2 Ensembl:ENSG00000171791 HGNC:990 HPRD:01045 MIM:151430 BCL2 Bin Zhao, Yue Liu, Oliver He BCL-XL/S BCL2L BCLX BCLXL BCLXS Bcl-X PPP1R52 bcl-xL bcl-xS WEB: http://www.ncbi.nlm.nih.gov/gene BCL2L1 BCL2-like 1 598 RP5-857M17.3 20q11.21 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0000910 (EC: IMP); GO_0001541 (EC: IEA); GO_0001701 (EC: IEA); GO_0001836 (EC: IDA, PMID: 9843949); GO_0005515 (EC: IPI, PMID: 10837489); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA); GO_0005737 (EC: IDA); GO_0005739 (EC: IDA); GO_0005741 (EC: IDA, PMID: 19767770); GO_0005741 (EC: NAS, PMID: 12667443); GO_0005741 (EC: TAS); GO_0005743 (EC: IEA); GO_0005759 (EC: IEA); GO_0005813 (EC: IDA); GO_0005829 (EC: IEA); GO_0006897 (EC: IEA); GO_0006915 (EC: TAS); GO_0007093 (EC: IMP); GO_0007281 (EC: IEA); GO_0007283 (EC: IEA); GO_0008283 (EC: IEA); GO_0008284 (EC: IEA); GO_0008584 (EC: IEA); GO_0008630 (EC: IEA); GO_0008637 (EC: TAS, PMID: 9393856); GO_0009566 (EC: IEA); GO_0010507 (EC: TAS, PMID: 18309324); GO_0016021 (EC: IEA); GO_0019050 (EC: IDA, PMID: 15231831); GO_0019901 (EC: IPI); GO_0030054 (EC: IEA); GO_0030672 (EC: IEA); GO_0031965 (EC: IEA); GO_0034097 (EC: IDA, PMID: 9184696); GO_0035872 (EC: TAS); GO_0040007 (EC: IEA); GO_0042802 (EC: IPI, PMID: 15131699); GO_0042803 (EC: IBA); GO_0043065 (EC: IEA); GO_0043066 (EC: IDA); GO_0043066 (EC: IMP, PMID: 17289999); GO_0043524 (EC: IEA); GO_0045087 (EC: TAS); GO_0046898 (EC: IEA); GO_0046902 (EC: IDA, PMID: 9843949); GO_0046982 (EC: IBA); GO_0051402 (EC: IEA); GO_0051434 (EC: IPI, PMID: 15901672); GO_0051881 (EC: IDA, PMID: 9843949); GO_0060154 (EC: IEA); GO_0071230 (EC: IEA); GO_0071312 (EC: IEA); GO_0071480 (EC: IEA); GO_0071839 (EC: IEA); GO_0090005 (EC: IDA); GO_0090201 (EC: IC); GO_0090201 (EC: IDA, PMID: 12667443); GO_0097136 (EC: IDA); GO_0097192 (EC: IBA); GO_0097193 (EC: TAS); GO_0097284 (EC: IEA); GO_1900118 (EC: IDA); GO_1902230 (EC: IDA, PMID: 16608847); GO_2000811 (EC: IMP, PMID: 15006356); GO_2001240 (EC: TAS, PMID: 8358789); GO_2001243 (EC: IDA, PMID: 12011449); GO_2001244 (EC: TAS) PMID: 7540278; 7644501; 7650367; 7834748; 8358789; 8596636; 8692274; 8929532; 9020082; 9027312; 9027313; 9111042; 9130713; 9153240; 9184696; 9192670; 9305851; 9326610; 9334338; 9372935; 9388232; 9389483; 9393856; 9430630; 9435230; 9488720; 9525867; 9539746; 9660918; 9675101; 9727492; 9731710; 9742125; 9765397; 9824152; 9843949; 9973195; 10049775; 10075695; 10195903; 10198631; 10217402; 10330179; 10365962; 10446169; 10467396; 10467399; 10620799; 10625696; 10679027; 10713718; 10716992; 10737788; 10802717; 10807576; 10837489; 10891504; 10949025; 11044452; 11054413; 11060313; 11077446; 11123279; 11126360; 11175750; 11206074; 11278245; 11279541; 11283018; 11342619; 11423909; 11437653; 11463391; 11463392; 11483855; 11494146; 11574549; 11583631; 11696595; 11714801; 11733517; 11739707; 11742726; 11756417; 11780052; 11788897; 11801602; 11815602; 11832478; 11859372; 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21139048; 21148306; 21173168; 21187157; 21203533; 21226954; 21256112; 21277008; 21292770; 21320495; 21339291; 21367852; 21396851; 21399876; 21424121; 21458670; 21527247; 21533126; 21567405; 21589877; 21639858; 21656147; 21659544; 21669490; 21674052; 21674599; 21726118; 21840391; 21852238; 21854985; 21856303; 21863213; 21887277; 21890473; 21900206; 21906983; 21952639; 21971866; 21980434; 21988832; 22009326; 22072718; 22084435; 22098591; 22099018; 22119486; 22127243; 22138435; 22141411; 22158966; 22160868; 22197371; 22211240; 22213163; 22219388; 22235227; 22240664; 22267549; 22354970; 22393362; 22403404; 22433870; 22440396; 22440942; 22454513; 22464442; 22486615; 22515821; 22522453; 22552851; 22589539; 22609401; 22617334; 22627140; 22670675; 22685558; 22686245; 22705850; 22729867; 22732506; 22797576; 22884477; 22892098; 22898820; 22933114; 22949227; 22960132; 23000965; 23013270; 23028682; 23051936; 23064052; 23079612; 23091012; 23171055; 23243017; 23275004; 23292448; 23333404; 23369735; 23392805; 23442864; 23475955; 23519249; 23562578; 23573264; 23708869; 23756231; 23798675; 23802633; 23812727; 23823868; 23887890; 23908595; 23954445; 23960074; 23977882; 24055032; 24091677; 24297914; 24313893 BCL2-like 1 Ensembl:ENSG00000171552 HGNC:992 HPRD:02497 MIM:600039 Vega:OTTHUMG00000032192 BCL2L1 Bin Zhao, Yue Liu, Oliver He ANON2 BULN2 WEB: http://www.ncbi.nlm.nih.gov/gene BDNF brain-derived neurotrophic factor 627 11p13 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0001657 (EC: IEA); GO_0001662 (EC: IEA); GO_0001666 (EC: IEA); GO_0002544 (EC: IEA); GO_0005169 (EC: IEA); GO_0005576 (EC: IEA); GO_0005737 (EC: ISS); GO_0006120 (EC: IEA); GO_0007399 (EC: TAS, PMID: 2236018); GO_0007406 (EC: IEA); GO_0007411 (EC: IEA); GO_0007412 (EC: IEA); GO_0007611 (EC: IEA); GO_0007631 (EC: IEA); GO_0008021 (EC: IEA); GO_0008038 (EC: IEA); GO_0008083 (EC: IEA); GO_0009725 (EC: IEA); GO_0014047 (EC: IEA); GO_0014076 (EC: IEA); GO_0016358 (EC: IEA); GO_0019222 (EC: IEA); GO_0021675 (EC: IEA); GO_0033189 (EC: IEA); GO_0042490 (EC: IEA); GO_0043524 (EC: IEA); GO_0045666 (EC: IEA); GO_0045843 (EC: IEA); GO_0046668 (EC: IEA); GO_0048170 (EC: IEA); GO_0048172 (EC: IEA); GO_0048471 (EC: ISS); GO_0048839 (EC: IEA); GO_0051965 (EC: IDA, PMID: 19036963); GO_0055093 (EC: IEA); GO_0060079 (EC: IEA); GO_0072347 (EC: IEA) PMID: 1339267; 1645620; 1889806; 1889807; 2025430; 2230938; 2236018; 7703225; 7961712; 8174548; 8527932; 8869564; 9118804; 9312147; 9387865; 9519408; 9580557; 9878821; 9990022; 10391209; 10493752; 10760298; 11152678; 11166915; 11214319; 11244490; 11408619; 11782995; 11836300; 11840487; 11855816; 11923430; 11935372; 12008958; 12130635; 12140770; 12140781; 12161822; 12192623; 12358753; 12359171; 12397373; 12477932; 12480128; 12524161; 12531456; 12553913; 12568867; 12694935; 12719654; 12738784; 12742659; 12753507; 12836135; 12842310; 12851636; 12888803; 12890761; 12900521; 12912764; 12921913; 12951204; 14566559; 14582140; 14623369; 14636373; 14642442; 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19944766; 19953912; 19956404; 19958603; 19961866; 19996106; 19997080; 20004415; 20006992; 20013430; 20014955; 20016225; 20022223; 20033742; 20034542; 20037522; 20042999; 20061032; 20067661; 20075215; 20079575; 20085561; 20087404; 20097294; 20098437; 20100784; 20102668; 20112124; 20125193; 20140603; 20141276; 20141627; 20142305; 20142488; 20147969; 20153759; 20156366; 20160224; 20163778; 20167454; 20169377; 20172611; 20172629; 20175187; 20175892; 20193311; 20195291; 20196181; 20201430; 20205668; 20207421; 20213725; 20215397; 20219210; 20220593; 20226536; 20227453; 20230085; 20301600; 20331634; 20334574; 20345896; 20346518; 20350583; 20351714; 20358425; 20395113; 20398943; 20400928; 20410295; 20410875; 20413850; 20418890; 20420877; 20428771; 20430595; 20433887; 20434221; 20436453; 20447730; 20456319; 20463055; 20467874; 20468064; 20478625; 20478633; 20478698; 20482942; 20483468; 20491609; 20491871; 20493546; 20515362; 20515664; 20520848; 20534741; 20537407; 20538960; 20547043; 20553751; 20553817; 20553872; 20556464; 20571754; 20573217; 20574532; 20579509; 20583129; 20589104; 20600926; 20602615; 20613678; 20615547; 20628086; 20631062; 20633049; 20638435; 20648653; 20649532; 20653606; 20655300; 20656764; 20662941; 20662942; 20663924; 20667416; 20667458; 20673758; 20674983; 20674984; 20682308; 20690185; 20691427; 20702703; 20703451; 20708907; 20712903; 20724581; 20726824; 20726825; 20728877; 20733583; 20734064; 20736000; 20736957; 20738025; 20738408; 20800603; 20816195; 20842321; 20843981; 20846878; 20849839; 20854879; 20856249; 20865733; 20874832; 20878119; 20921514; 20921572; 20932956; 20933336; 20935630; 20943059; 20945028; 20946355; 20953813; 20957650; 20959432; 20965453; 20966902; 20970479; 20978454; 21037213; 21039634; 21041608; 21044653; 21047554; 21048129; 21049025; 21049304; 21056046; 21057246; 21063127; 21063237; 21071619; 21081796; 21085492; 21098877; 21103954; 21115199; 21115268; 21116262; 21129438; 21131999; 21133708; 21135555; 21143020; 21167606; 21167764; 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22585743; 22593075; 22596272; 22610920; 22617010; 22626951; 22633192; 22642961; 22652301; 22654603; 22669612; 22679788; 22682508; 22694150; 22695185; 22699449; 22704695; 22708958; 22710963; 22719055; 22720171; 22735491; 22750275; 22766130; 22768299; 22773554; 22803145; 22806912; 22813992; 22815222; 22832849; 22833197; 22842573; 22844024; 22848609; 22856871; 22859933; 22877924; 22880079; 22880108; 22883353; 22886603; 22892716; 22895657; 22901763; 22906736; 22911909; 22940753; 22941316; 22952960; 22963854; 22965830; 22974102; 22989210; 23020799; 23020846; 23022197; 23023098; 23026378; 23034254; 23041465; 23058261; 23058367; 23062292; 23065263; 23077504; 23086941; 23088179; 23103549; 23111884; 23114813; 23123787; 23124710; 23128606; 23132269; 23133609; 23136540; 23137999; 23140671; 23149719; 23152767; 23157339; 23165919; 23168995; 23175149; 23182421; 23184535; 23201631; 23215636; 23221871; 23229156; 23240009; 23245944; 23247064; 23250003; 23253673; 23253771; 23255668; 23258230; 23263460; 23266638; 23269345; 23271640; 23274291; 23277136; 23285275; 23288242; 23303061; 23312562; 23313276; 23318672; 23319002; 23326649; 23333821; 23337827; 23341118; 23357445; 23383270; 23420490; 23422958; 23426664; 23429848; 23431394; 23433505; 23438165; 23451258; 23460828; 23461616; 23469118; 23487199; 23519890; 23532065; 23532066; 23550806; 23563607; 23567599; 23570723; 23576602; 23576701; 23582695; 23593198; 23593393; 23609403; 23619509; 23624487; 23640704; 23643991; 23698315; 23704927; 23733090; 23748016; 23769397; 23775641; 23823988; 23832605; 23835043; 23838134; 23859665; 23874483; 23899746; 23918043; 23923080; 23929745; 23989258; 23995205; 23995212; 24047966; 24141084; 24276217; 24300806; 24523540; 24523553 brain-derived neurotrophic factor Ensembl:ENSG00000176697 HGNC:1033 HPRD:00214 MIM:113505 Vega:OTTHUMG00000178797 BDNF Bin Zhao, Yue Liu, Oliver He FP497 WEB: http://www.ncbi.nlm.nih.gov/gene BID BH3 interacting domain death agonist 637 22q11.1 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0001836 (EC: IDA, PMID: 17052454); GO_0005123 (EC: TAS, PMID: 8918887); GO_0005515 (EC: IPI, PMID: 12624108); GO_0005739 (EC: TAS, PMID: 9727491); GO_0005741 (EC: TAS); GO_0005829 (EC: TAS); GO_0006626 (EC: IEA); GO_0006915 (EC: TAS); GO_0006919 (EC: IEA); GO_0007420 (EC: IEA); GO_0008625 (EC: TAS, PMID: 9727491); GO_0008637 (EC: TAS, PMID: 9727492); GO_0016020 (EC: TAS, PMID: 8918887); GO_0031625 (EC: IEA); GO_0032355 (EC: IEA); GO_0032461 (EC: IDA, PMID: 19074440); GO_0032464 (EC: IDA); GO_0032592 (EC: IEA); GO_0034349 (EC: IEA); GO_0042127 (EC: IEA); GO_0042770 (EC: TAS, PMID: 18309324); GO_0043065 (EC: IMP, PMID: 17289999); GO_0051260 (EC: IEA); GO_0051402 (EC: TAS, PMID: 16167175); GO_0090150 (EC: IDA); GO_0090200 (EC: IGI); GO_0090200 (EC: IMP, PMID: 17289999); GO_0097193 (EC: TAS); GO_1900740 (EC: TAS); GO_1901030 (EC: TAS); GO_1902108 (EC: IEA); GO_2000045 (EC: IEA); GO_2001238 (EC: IMP); GO_2001244 (EC: TAS) PMID: 7774948; 7929347; 8918887; 9463381; 9721221; 9727491; 9727492; 9790773; 10089877; 10364179; 10629050; 10950869; 11085743; 11099414; 11114298; 11399776; 11544326; 11583622; 11583631; 11585909; 11741882; 11790791; 11805084; 11832478; 11929871; 11940658; 11971973; 12000759; 12061801; 12097160; 12193163; 12196516; 12404116; 12419244; 12477932; 12598529; 12624108; 12754217; 12766488; 12804595; 12808108; 12871587; 12934063; 14581476; 14583606; 14702039; 14716828; 14769944; 15024076; 15117953; 15123718; 15146197; 15173176; 15231831; 15323553; 15353804; 15461802; 15489334; 15501827; 15520201; 15574335; 15592455; 15615731; 15637055; 15659383; 15692567; 15694340; 15721256; 15772077; 15809076; 16077201; 16167175; 16172118; 16341674; 16344560; 16380381; 16475813; 16485030; 16697956; 16908521; 16964285; 16987815; 17052454; 17200714; 17226776; 17283187; 17289999; 17308307; 17431792; 17488272; 17534194; 17549073; 17635912; 17666167; 17762183; 17765974; 17855051; 18029348; 18089817; 18165867; 18166654; 18173728; 18195012; 18297401; 18309324; 18317451; 18373075; 18469004; 18593990; 18648372; 18665919; 18723680; 18838202; 18925930; 19029793; 19046991; 19052714; 19074440; 19074885; 19219602; 19233849; 19246452; 19381674; 19423537; 19454696; 19640637; 19641510; 19670908; 19711428; 19820711; 19890662; 19913121; 19918914; 19929986; 20140092; 20187936; 20356928; 20379614; 20392206; 20404718; 20453000; 20628086; 20801175; 20802294; 20855536; 20877624; 21041309; 21060336; 21072056; 21113148; 21139048; 21148306; 21178828; 21223573; 21367852; 21382479; 21613222; 21642428; 21751259; 21856753; 21859891; 21900206; 21906983; 22052011; 22115752; 22130162; 22189507; 22213163; 22246181; 22339673; 22354970; 22393005; 22416135; 22464442; 22860893; 22939629; 22964611; 23019260; 23192964; 23333919; 23352961; 23383273; 23418437; 23604079; 23744079; 23824909; 24074954; 24158446 BH3 interacting domain death agonist Ensembl:ENSG00000015475 HGNC:1050 HPRD:03590 MIM:601997 Vega:OTTHUMG00000150087 BID Bin Zhao, Yue Liu, Oliver He BLR1 CD185 MDR15 WEB: http://www.ncbi.nlm.nih.gov/gene CXCR5 chemokine (C-X-C motif) receptor 5 643 11q23.3 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0004930 (EC: TAS, PMID: 1425907); GO_0005515 (EC: IPI); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 1425907); GO_0006928 (EC: TAS, PMID: 1425907); GO_0006935 (EC: IEA); GO_0006955 (EC: IEA); GO_0007186 (EC: TAS, PMID: 1425907); GO_0016494 (EC: IEA); GO_0032467 (EC: IMP); GO_0042113 (EC: IEA); GO_0048535 (EC: IEA) PMID: 1425907; 7639692; 9463416; 9486651; 11688722; 11714765; 12070001; 12171958; 12324654; 12447991; 12477932; 12578791; 12620646; 14618028; 14763921; 15713799; 15780119; 16225771; 16318584; 16344560; 16888899; 17015714; 17018614; 17652619; 17786442; 18528326; 18577758; 18780835; 19074885; 19228923; 19375853; 19536742; 19610059; 19913121; 19955043; 20412587; 20628086; 20809769; 21399635; 21471443; 21642390; 21750724; 21785430; 21833088; 22607768; 22707196; 22840692; 22913878; 22951725; 23128233; 23189125; 23250934; 23739915; 23807677; 24035365; 24138884 chemokine (C-X-C motif) receptor 5 HGNC:1060 HPRD:03367 MIM:601613 CXCR5 Bin Zhao, Yue Liu, Oliver He ARMD14 CO2 WEB: http://www.ncbi.nlm.nih.gov/gene C2 complement component 2 717 DADB-122G4.1 6p21.3 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0004252 (EC: IEA); GO_0005576 (EC: TAS); GO_0005615 (EC: TAS, PMID: 8621452); GO_0006956 (EC: TAS); GO_0006958 (EC: IEA); GO_0030449 (EC: TAS); GO_0045087 (EC: TAS) PMID: 162484; 978135; 1084023; 1350302; 1531292; 1577763; 1701385; 2091785; 2493504; 2582254; 2949737; 2997031; 3315100; 3546307; 3643061; 6019133; 6149575; 6199794; 6555044; 6922702; 8120386; 8125298; 8175701; 8299689; 8326124; 8621452; 9453398; 9670930; 10072631; 10734221; 10946278; 10946292; 11222683; 11341920; 12477932; 12823772; 12878586; 14702039; 15199963; 15489334; 16335952; 16518403; 16670774; 17482263; 17576744; 18069935; 18174230; 18493315; 18515590; 18541650; 18806293; 18806297; 18936151; 18987644; 19015224; 19117936; 19169232; 19180512; 19197355; 19237749; 19259132; 19336475; 19344414; 19399715; 19423540; 19430225; 19556007; 19661236; 19696172; 19851445; 19913121; 19948975; 20157618; 20205591; 20378180; 20381870; 20385819; 20385826; 20406964; 20417301; 20438785; 20523265; 20628086; 20679960; 20801516; 20888482; 21105107; 21665990; 21764829; 21881993; 22232432; 22273503; 22566634; 22610944; 22705344; 22869612; 23060141; 23233260; 23455636; 23535732; 23577725; 23620142 complement component 2 Ensembl:ENSG00000166278 HGNC:1248 HPRD:08939 MIM:613927 Vega:OTTHUMG00000031190 C2 Bin Zhao, Yue Liu, Oliver He AHUS5 ARMD9 ASP C3a C3b CPAMD1 HEL-S-62p WEB: http://www.ncbi.nlm.nih.gov/gene C3 complement component 3 718 19p13.3-p13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0001798 (EC: IEA); GO_0001934 (EC: IDA, PMID: 15833747); GO_0001970 (EC: IEA); GO_0004866 (EC: IEA); GO_0005102 (EC: TAS, PMID: 9164946); GO_0005515 (EC: IPI, PMID: 11705926); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA); GO_0005886 (EC: TAS); GO_0006631 (EC: IEA); GO_0006954 (EC: IEA); GO_0006955 (EC: TAS, PMID: 4097977); GO_0006956 (EC: TAS); GO_0006957 (EC: TAS); GO_0006958 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10085065); GO_0007186 (EC: TAS, PMID: 9164946); GO_0010575 (EC: IDA, PMID: 16452172); GO_0010828 (EC: IDA, PMID: 15833747); GO_0010866 (EC: IDA, PMID: 10432298); GO_0010884 (EC: IDA, PMID: 9555951); GO_0030449 (EC: TAS); GO_0031715 (EC: IDA, PMID: 15833747); GO_0045087 (EC: TAS); GO_0045745 (EC: IDA, PMID: 15833747); GO_0045766 (EC: IEA); GO_0050766 (EC: IEA); GO_0050776 (EC: TAS); GO_0070062 (EC: IDA); GO_0072562 (EC: IDA) PMID: 162484; 279011; 695691; 1238393; 1323007; 1350678; 1401896; 1531292; 1577777; 1703437; 1717583; 1830068; 1861080; 1976733; 2387584; 2473125; 2579379; 2584723; 2824652; 3052276; 3260670; 3279119; 3421908; 3488995; 3546307; 3871945; 4062888; 4097977; 6175959; 6203109; 6912277; 7512600; 7535292; 7539791; 7590866; 7642209; 7893437; 7911492; 7961791; 8406564; 8416818; 8471312; 8630395; 8648130; 8702752; 8845016; 8943712; 9059512; 9164946; 9291131; 9544576; 9555951; 9596584; 9605165; 9719152; 9988761; 10078261; 10079271; 10085065; 10358196; 10382758; 10432298; 10608878; 10610782; 10622723; 10882776; 10946275; 11058592; 11073102; 11086104; 11342658; 11367533; 11387479; 11513971; 11684127; 11705926; 11773063; 11785295; 11803045; 11813855; 11854358; 11884542; 11896391; 11939578; 11979403; 12006395; 12165538; 12477932; 12511407; 12540846; 12645945; 12679444; 12754519; 12761187; 12816955; 12878586; 12893820; 12942785; 12967641; 14527961; 14563826; 14639503; 14662858; 14702039; 14760718; 15033778; 15090635; 15187133; 15199963; 15241561; 15278436; 15342556; 15381670; 15383607; 15489226; 15590640; 15648851; 15713467; 15713468; 15749882; 15810889; 15833747; 15872081; 16148107; 16148115; 16177781; 16199891; 16263699; 16301317; 16335952; 16339538; 16355111; 16449793; 16452172; 16516157; 16530040; 16570073; 16627066; 16670774; 16809564; 16823297; 16889542; 16893076; 17051150; 17051152; 17051160; 17060630; 17172439; 17322907; 17372315; 17482181; 17498719; 17502296; 17520688; 17634448; 17684013; 17703412; 17762737; 17767156; 17984207; 18039528; 18039777; 18054386; 18061265; 18174230; 18206145; 18247123; 18253759; 18325906; 18356838; 18383369; 18434316; 18456336; 18562232; 18562603; 18566738; 18572187; 18585783; 18596911; 18631248; 18671285; 18682851; 18694577; 18702682; 18755462; 18760301; 18796626; 18802120; 18805911; 18854167; 18936151; 18974840; 19005416; 19015224; 19017934; 19022911; 19028820; 19028829; 19048105; 19112495; 19117936; 19131662; 19164292; 19168221; 19179465; 19196712; 19202148; 19225544; 19234341; 19246358; 19247692; 19258923; 19259132; 19263529; 19265162; 19328844; 19336475; 19344414; 19387462; 19399715; 19407382; 19423540; 19454698; 19457998; 19503104; 19505474; 19549636; 19559392; 19590060; 19661236; 19665237; 19670317; 19680263; 19694644; 19703145; 19767107; 19773279; 19797206; 19823576; 19825847; 19828715; 19834535; 19843088; 19850835; 19861685; 19878567; 19899988; 19913121; 19913840; 19939777; 19948975; 20089077; 20091675; 20104494; 20105190; 20105310; 20109314; 20139276; 20139773; 20157618; 20173020; 20188594; 20237496; 20238042; 20301541; 20378178; 20379614; 20381870; 20385819; 20385826; 20395963; 20406964; 20438785; 20453728; 20498262; 20503287; 20513133; 20523265; 20576771; 20603037; 20628086; 20628624; 20639865; 20644161; 20664795; 20706769; 20807366; 20817881; 20837143; 20841369; 20852386; 20861866; 20862287; 20888482; 20926033; 20926148; 20951140; 21055811; 21085669; 21163532; 21205667; 21270401; 21308746; 21402993; 21404895; 21414106; 21415311; 21435440; 21462136; 21464960; 21501302; 21527715; 21555552; 21566112; 21642543; 21658310; 21664558; 21665990; 21706294; 21733505; 21788512; 21801245; 21813769; 21816153; 21953030; 21966368; 21988832; 22007489; 22089112; 22132894; 22138144; 22145905; 22153860; 22171262; 22174912; 22176838; 22194611; 22228414; 22234447; 22246034; 22250080; 22253322; 22258234; 22264230; 22273503; 22324951; 22361228; 22390383; 22393059; 22415003; 22456601; 22518841; 22542119; 22553783; 22565852; 22635230; 22669319; 22673887; 22705344; 22718507; 22792353; 22851413; 22863782; 22878256; 22909298; 22930722; 22996269; 23028341; 23031360; 23056509; 23068452; 23071281; 23098807; 23134230; 23206327; 23209669; 23233260; 23235567; 23285141; 23337555; 23356914; 23365660; 23385359; 23390291; 23427180; 23455636; 23537682; 23619360; 23628799; 23639844; 23661701; 23719603; 23750785; 23833239; 23878142; 23956345; 23982842; 24239583; 24287422; 24367091 complement component 3 Ensembl:ENSG00000125730 HGNC:1318 HPRD:00400 MIM:120700 Vega:OTTHUMG00000150335 C3 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene C6 complement component 6 729 5p13 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0001701 (EC: IEA); GO_0001970 (EC: IEA); GO_0005515 (EC: IPI, PMID: 17474147); GO_0005576 (EC: TAS); GO_0005579 (EC: IEA); GO_0006956 (EC: TAS, PMID: 2808363); GO_0006958 (EC: IEA); GO_0019835 (EC: IEA); GO_0030449 (EC: TAS); GO_0045087 (EC: TAS); GO_0045766 (EC: IEA) PMID: 1387399; 1672663; 2468158; 2789218; 2808363; 3052276; 3192535; 3764345; 8101442; 8364540; 8512929; 8805625; 9366265; 9472666; 9856498; 10551839; 12477932; 14757862; 15489334; 15845028; 16169070; 16335952; 16344560; 17257682; 17474147; 18842294; 19162005; 19344414; 19423540; 19665237; 19864026; 19913121; 20237496; 20406964; 20438785; 20459687; 20628086; 21704099; 21988832; 22267737; 22288589; 22500023; 23149075; 23750785 complement component 6 C6 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene C7 complement component 7 730 5p13 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0005576 (EC: TAS); GO_0005579 (EC: IEA); GO_0006883 (EC: IEA); GO_0006956 (EC: TAS, PMID: 3335508); GO_0006957 (EC: IEA); GO_0006958 (EC: IEA); GO_0019835 (EC: IEA); GO_0030449 (EC: TAS); GO_0045087 (EC: TAS) PMID: 1387399; 1517503; 1672663; 2792129; 3052276; 3335508; 7523157; 7730625; 7814888; 8345200; 8364540; 8814254; 8871666; 8892662; 9218625; 9856499; 10551839; 10882776; 10886241; 11378347; 12477932; 12595902; 14760718; 15383587; 15489334; 15879120; 15889368; 16335952; 17266113; 18029348; 18842294; 19162005; 19179470; 19221116; 19344414; 19419965; 19423540; 19834535; 19864026; 19913121; 19931914; 20237496; 20406964; 20438785; 20628086; 21881993; 22206826; 23943762 complement component 7 C7 Bin Zhao, Yue Liu, Oliver He CA-I CAB Car1 HEL-S-11 WEB: http://www.ncbi.nlm.nih.gov/gene CA1 carbonic anhydrase I 759 8q21.2 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0004089 (EC: IEA); GO_0005829 (EC: TAS); GO_0006730 (EC: IEA); GO_0008270 (EC: IEA); GO_0015701 (EC: TAS); GO_0044281 (EC: TAS) PMID: 406674; 804171; 827930; 1602151; 1916821; 2121614; 2511043; 3088232; 3104879; 3124707; 4207120; 4217196; 4625868; 4632246; 6781336; 7574487; 7866410; 9879596; 11392054; 11680594; 12009884; 12477932; 14675565; 15342556; 15489334; 15836783; 15837325; 16870440; 17192395; 17314045; 17464559; 18029348; 19536309; 20624682; 21143847; 21900206; 21988832; 22360420; 22416960; 22619369; 22996014; 23557951; 23720494 carbonic anhydrase I Ensembl:ENSG00000133742 HGNC:1368 HPRD:00265 MIM:114800 Vega:OTTHUMG00000164941 CA1 Bin Zhao, Yue Liu, Oliver He CALML2 CAMI CPVT4 DD132 PHKD caM WEB: http://www.ncbi.nlm.nih.gov/gene CALM1 calmodulin 1 (phosphorylase kinase, delta) 801 14q32.11 20140408 9606 14 protein-coding Official from a nomenclature committee PMID: 1332771; 1519061; 1520270; 1544444; 1660262; 1790714; 1872871; 2062825; 2123288; 2161834; 2223880; 2445749; 2455687; 2487274; 2507540; 2853949; 3111527; 3350007; 3472906; 6385987; 6847627; 7490111; 7525583; 7559563; 7593266; 7607248; 7642608; 7836475; 7887964; 7925473; 7947686; 8206911; 8226798; 8312049; 8314583; 8486648; 8573130; 8625412; 8626479; 8639568; 8663089; 8670801; 8756646; 8769426; 8780394; 8824319; 8862395; 8872303; 8900147; 8901523; 9003189; 9009191; 9092566; 9096366; 9115241; 9188503; 9202019; 9278050; 9282777; 9341188; 9362478; 9374536; 9490638; 9512352; 9658102; 9677319; 9681195; 9728925; 9753452; 9774336; 9822657; 9837900; 9923700; 9952395; 10026195; 10026200; 10075657; 10075700; 10088721; 10333484; 10411641; 10416864; 10488094; 10547355; 10625668; 10681496; 10692436; 10747990; 10748158; 10757985; 10816571; 10823944; 10827182; 10852921; 10860555; 10880439; 10893241; 10899953; 11054265; 11072229; 11171103; 11178895; 11248124; 11278607; 11323678; 11395482; 11397791; 11448995; 11457836; 11585916; 11734550; 11736632; 11741295; 11807557; 11811958; 11827172; 11847276; 11953448; 11981030; 11984006; 12006621; 12032157; 12034722; 12051765; 12135876; 12153558; 12202484; 12221128; 12223552; 12358748; 12408866; 12446675; 12475216; 12477932; 12509414; 12556500; 12594225; 12610000; 12626507; 12626508; 12715898; 12724311; 12727204; 12805215; 12808128; 12809501; 12821674; 12901717; 12925680; 14551202; 14594800; 14613930; 14695896; 14960328; 14985437; 15048887; 15087444; 15104175; 15147735; 15161933; 15229223; 15316014; 15494036; 15522886; 15583004; 15632291; 15664518; 15670850; 15746150; 15746172; 15746192; 15806159; 15817490; 15840729; 15851513; 15902271; 15990872; 16013055; 16030015; 16051151; 16051665; 16084495; 16127172; 16154564; 16229872; 16258073; 16299511; 16338416; 16344560; 16359877; 16512683; 16522924; 16613843; 16627785; 16760425; 16799092; 17046994; 17202341; 17314412; 17379601; 17568776; 17569884; 17580302; 17654480; 17696464; 17884685; 17942410; 17975119; 18001530; 18070603; 18178620; 18370588; 18452398; 18553937; 18567582; 18768750; 18940010; 18989758; 19023099; 19034380; 19080622; 19133300; 19322201; 19358819; 19596235; 19614740; 19615732; 19658100; 19667195; 19855925; 19913121; 20012528; 20103772; 20301466; 20468064; 20488189; 20562859; 20618440; 20628086; 20639865; 20705923; 20738160; 20876399; 20946164; 20956522; 21047202; 21102557; 21124984; 21145461; 21150319; 21167176; 21372285; 21439835; 21555518; 21640070; 21664913; 21726808; 21730051; 21799007; 21901608; 21963094; 21988832; 22004035; 22009783; 22009847; 22044025; 22100452; 22266860; 22295092; 22323446; 22342729; 22363329; 22437832; 22451665; 22486744; 22505724; 22588125; 22767601; 22768143; 22779921; 22801425; 22803592; 22856685; 22939629; 22996592; 23019329; 23040497; 23152621; 23159936; 23235156; 23285036; 23300090; 23322042; 23370391; 23388215; 23398456; 23437200; 23438482; 23455922; 23457304; 23552119; 23624269; 23658780; 23662433; 23743201; 23755207; 23760276; 23798571; 23831686; 23838429; 23967355; 24032677; 24088894; 24457600 calmodulin 1 (phosphorylase kinase, delta) Ensembl:ENSG00000198668 HGNC:1442 HPRD:00241 MIM:114180 Vega:OTTHUMG00000171044 CALM1 Bin Zhao, Yue Liu, Oliver He CAMII PHKD PHKD2 WEB: http://www.ncbi.nlm.nih.gov/gene CALM2 calmodulin 2 (phosphorylase kinase, delta) 805 2p21 20140408 9606 2 protein-coding Official from a nomenclature committee PMID: 2223880; 2445749; 3111527; 8076819; 8226798; 8312049; 8314583; 8573130; 8780394; 8862395; 9096366; 9242710; 9278050; 9282777; 9362478; 9658102; 9681195; 9923700; 10075700; 10416864; 10625668; 10692436; 10757985; 10816571; 10823944; 10899953; 11054265; 11072229; 11591728; 11736632; 11741295; 11847276; 11953448; 11981030; 12032157; 12051765; 12153558; 12189141; 12221128; 12477932; 12577052; 14613930; 14702039; 15225611; 15342556; 15632291; 15723066; 16051665; 16127172; 16169070; 16189514; 16229872; 16545345; 17046994; 17189291; 17202341; 17687619; 18370588; 18553937; 19584346; 19913121; 20000738; 20012528; 20198394; 20379146; 20379614; 20628086; 20639865; 20876399; 20956522; 21047202; 21078624; 21139048; 21145461; 21546767; 21565611; 21726808; 21799007; 21890473; 21906983; 21963094; 21987572; 21988832; 22053931; 22323446; 22331908; 22505724; 22633975; 22939629; 23000965; 23349634; 23388215; 23798571 calmodulin 2 (phosphorylase kinase, delta) Ensembl:ENSG00000143933 HGNC:1445 HPRD:00242 MIM:114182 Vega:OTTHUMG00000128850 CALM2 Bin Zhao, Yue Liu, Oliver He CANP2 CANPL2 CANPml mCANP WEB: http://www.ncbi.nlm.nih.gov/gene CAPN2 calpain 2, (m/II) large subunit 824 1q41-q42 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000785 (EC: IEA); GO_0001666 (EC: IEA); GO_0001824 (EC: IEA); GO_0004198 (EC: IBA); GO_0004198 (EC: ISS); GO_0005509 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10639123); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA); GO_0005737 (EC: ISS); GO_0005783 (EC: IDA, PMID: 14559243); GO_0005794 (EC: IDA, PMID: 14559243); GO_0005829 (EC: IDA, PMID: 12150984); GO_0005886 (EC: IDA, PMID: 12150984); GO_0006508 (EC: IBA); GO_0006508 (EC: ISS); GO_0007520 (EC: IEA); GO_0008092 (EC: NAS, PMID: 12150984); GO_0008234 (EC: TAS, PMID: 2209092); GO_0016540 (EC: IEA); GO_0030425 (EC: ISS); GO_0030864 (EC: TAS, PMID: 12150984); GO_0031143 (EC: IDA, PMID: 14559243); GO_0045121 (EC: IDA, PMID: 14559243); GO_0045121 (EC: IDA, Qualifier: colocalizes_with, PMID: 12150984); GO_0046982 (EC: IEA); GO_0051493 (EC: TAS, PMID: 12150984); GO_0051603 (EC: IC, PMID: 12150984); GO_0070062 (EC: IDA, PMID: 19056867); GO_0071230 (EC: ISS); GO_0097038 (EC: IDA, PMID: 14559243) PMID: 1067155; 1527057; 2209092; 2539381; 2852952; 3038169; 8561910; 8900201; 8954122; 9213221; 9337844; 9407132; 9562261; 9873017; 10639123; 10666632; 10671558; 10830966; 10944468; 10978167; 11023826; 11387205; 11483505; 11517928; 11673052; 11853546; 12000759; 12070670; 12130691; 12150984; 12477932; 12665801; 12783889; 14559243; 14688278; 14702039; 14976200; 14980313; 14993287; 15302874; 15471877; 15489334; 15590481; 15817486; 15950654; 16310784; 16344560; 16361262; 16436382; 16530191; 16598790; 16652152; 16816119; 17192410; 17261541; 17359359; 17596297; 17643375; 17650508; 17897354; 18032503; 18239623; 18332219; 18340456; 18568448; 19056867; 19074885; 19422794; 19720936; 19752040; 19756344; 19861418; 19913121; 19946123; 20041182; 20070945; 20150423; 20193680; 20379614; 20453000; 20618160; 20628086; 20729206; 20730561; 20924799; 20962236; 21086148; 21117903; 21139048; 21152086; 21185840; 21374734; 21839844; 21890473; 21906983; 21963094; 22064597; 22335024; 22435971; 22623320; 22629380; 22711986; 22745213; 22863883; 22990118; 23000965; 23140395; 23389291; 23466492; 23538341; 23667531; 23733271; 23940116 calpain 2, (m/II) large subunit Ensembl:ENSG00000162909 HGNC:1479 HPRD:00254 MIM:114230 Vega:OTTHUMG00000037376 CAPN2 Bin Zhao, Yue Liu, Oliver He ICE IL1BC P45 WEB: http://www.ncbi.nlm.nih.gov/gene CASP1 caspase 1, apoptosis-related cysteine peptidase 834 11q23 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0001666 (EC: IEA); GO_0004197 (EC: IBA); GO_0004197 (EC: TAS); GO_0005515 (EC: IPI, PMID: 11374873); GO_0005576 (EC: IEA); GO_0005737 (EC: IBA); GO_0005829 (EC: TAS); GO_0006508 (EC: IDA, PMID: 12888622); GO_0006915 (EC: TAS, PMID: 7876192); GO_0006919 (EC: TAS, PMID: 10799503); GO_0007165 (EC: TAS, PMID: 1373520); GO_0008656 (EC: TAS, PMID: 10799503); GO_0032496 (EC: IEA); GO_0032611 (EC: IEA); GO_0033198 (EC: IEA); GO_0035872 (EC: TAS); GO_0043123 (EC: IEP, PMID: 12761501); GO_0045087 (EC: TAS); GO_0050717 (EC: IEA); GO_0050718 (EC: IEA); GO_0050727 (EC: IBA); GO_0051882 (EC: IEA); GO_0060081 (EC: IEA); GO_0070269 (EC: IEA); GO_0071260 (EC: IEP, PMID: 19593445); GO_0071310 (EC: IDA, PMID: 19158679); GO_0072557 (EC: IBA); GO_0072557 (EC: ISS); GO_0072558 (EC: IDA, PMID: 12191486); GO_0072559 (EC: IDA, PMID: 15030775); GO_0097169 (EC: IDA, PMID: 19158676); GO_0097194 (EC: IBA) PMID: 1321594; 1373520; 1574116; 1919001; 7642516; 7721861; 7797510; 7876192; 8034320; 8035875; 8044845; 8125298; 8861900; 8962078; 8978814; 8999548; 9002959; 9070648; 9115219; 9190289; 9219695; 9250871; 9334240; 9334338; 9435230; 9535906; 9548463; 9593687; 9632733; 9705209; 9705938; 9727491; 9792675; 9804161; 9830039; 9875225; 9894612; 9987822; 9990034; 10069390; 10329646; 10353249; 10438581; 10477277; 10510468; 10660263; 10708425; 10799503; 11085743; 11226410; 11374873; 11390368; 11432859; 11437653; 11438643; 11472070; 11536016; 11684016; 11821383; 11953316; 11967258; 11997061; 12019269; 12096920; 12170183; 12191486; 12215842; 12387869; 12459189; 12459463; 12477932; 12628757; 12692130; 12761501; 12888622; 14584052; 14669344; 15030775; 15039421; 15107016; 15296730; 15326478; 15383541; 15471361; 15489334; 15498465; 15561713; 15749123; 15809717; 16037825; 16087165; 16123779; 16260731; 16286016; 16405550; 16428475; 16575408; 16621994; 16778130; 16780720; 16785446; 16817903; 16903774; 16920334; 17036048; 17173859; 17196042; 17207965; 17303764; 17360653; 17418785; 17477815; 17597823; 17623017; 17703412; 17959595; 18029348; 18209072; 18263705; 18263805; 18304957; 18329368; 18523309; 18550243; 18577712; 18590738; 18799371; 18828051; 18981155; 19013323; 19074885; 19117953; 19141860; 19158676; 19158679; 19258923; 19269008; 19275586; 19382257; 19414860; 19439663; 19573080; 19593445; 19648107; 19737897; 19773279; 19779610; 19825518; 19833722; 19913121; 20038581; 20048342; 20060974; 20170165; 20184726; 20197547; 20402676; 20485444; 20503287; 20628086; 20808838; 20852925; 20855536; 20959405; 21037509; 21048031; 21052690; 21311905; 21320026; 21463955; 21757759; 21792841; 21832064; 21862576; 21862623; 22046355; 22046441; 22195745; 22227487; 22491736; 22537218; 22833538; 22837397; 23021143; 23209292; 23226468; 23236067; 23278288; 23386603; 23508996; 23590971; 23637985; 23703390; 23793845; 23839215; 23884363; 24022484; 24356306 caspase 1, apoptosis-related cysteine peptidase Ensembl:ENSG00000137752 HGNC:1499 HPRD:00977 MIM:147678 Vega:OTTHUMG00000048072 CASP1 Bin Zhao, Yue Liu, Oliver He CASP-2 ICH1 NEDD-2 NEDD2 PPP1R57 WEB: http://www.ncbi.nlm.nih.gov/gene CASP2 caspase 2, apoptosis-related cysteine peptidase 835 7q34-q35 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0001554 (EC: IEA); GO_0003407 (EC: IEA); GO_0004197 (EC: IDA, PMID: 10980123); GO_0005515 (EC: IPI, PMID: 11076957); GO_0005634 (EC: TAS, PMID: 18309324); GO_0005737 (EC: IBA); GO_0005739 (EC: IEA); GO_0005829 (EC: TAS); GO_0006915 (EC: NAS, PMID: 11156409); GO_0006977 (EC: IMP); GO_0007420 (EC: IEA); GO_0007568 (EC: IEA); GO_0008630 (EC: IBA); GO_0008630 (EC: TAS, PMID: 18309324); GO_0016020 (EC: IEA); GO_0016485 (EC: IDA, PMID: 9044836); GO_0019899 (EC: ISS, PMID: 11076957); GO_0019904 (EC: IPI, PMID: 9044836); GO_0035234 (EC: IEA); GO_0043065 (EC: IDA, PMID: 10980123); GO_0043281 (EC: TAS); GO_0043525 (EC: IEA); GO_0048011 (EC: TAS); GO_0071260 (EC: IEP, PMID: 19593445); GO_0097153 (EC: IEA); GO_0097190 (EC: TAS, PMID: 18309324); GO_0097192 (EC: IBA); GO_0097194 (EC: TAS, PMID: 18309324); GO_2001235 (EC: IEA) PMID: 7789948; 8044845; 8087842; 8780721; 8962078; 8985253; 9044836; 9228018; 9261102; 9560245; 9695946; 9792675; 9847074; 10079193; 10329646; 10791974; 10980123; 11076957; 11156409; 11278287; 11313953; 11350957; 11399776; 11425872; 11823470; 11830582; 11832478; 11972030; 12011445; 12065594; 12107826; 12145703; 12193789; 12477715; 12477932; 12584573; 12598307; 12787561; 12837286; 12853948; 12920126; 14584591; 14623896; 14647455; 14701762; 14702039; 14713958; 14716300; 15073321; 15173176; 15262979; 15297885; 15489334; 15500642; 15511269; 15555560; 15590671; 15735701; 15817479; 15843892; 15882978; 16172118; 16193064; 16227610; 16344560; 16360037; 16387548; 16652156; 16701639; 16777994; 16822901; 16843824; 17079734; 17159900; 17195089; 17627033; 17637755; 17902043; 17945178; 18166155; 18238895; 18309324; 18375382; 18413747; 18418048; 18723680; 18840686; 19074885; 19269008; 19322201; 19347032; 19414860; 19453261; 19573080; 19593445; 19604093; 19715609; 19730412; 19738422; 19773279; 19935698; 20143425; 20158568; 20187765; 20208132; 20402676; 20453000; 20819778; 20855536; 20978129; 21051981; 21332795; 21415862; 21475302; 21726810; 21828056; 21900206; 21903589; 21906983; 21940110; 21988832; 22002103; 22077397; 22174370; 22201672; 22396545; 22486813; 22505724; 22531785; 22825847; 23042294; 23404198; 23469978; 23553630; 23568547; 24250222; 24321384 caspase 2, apoptosis-related cysteine peptidase Ensembl:ENSG00000106144 HGNC:1503 HPRD:02800 MIM:600639 Vega:OTTHUMG00000023641 CASP2 Bin Zhao, Yue Liu, Oliver He CPP32 CPP32B SCA-1 WEB: http://www.ncbi.nlm.nih.gov/gene CASP3 caspase 3, apoptosis-related cysteine peptidase 836 4q34 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0001782 (EC: IEA); GO_0001836 (EC: IEA); GO_0004190 (EC: EXP); GO_0004197 (EC: IDA, PMID: 19240112); GO_0004197 (EC: TAS); GO_0004861 (EC: IEA); GO_0005515 (EC: IPI, PMID: 16501604); GO_0005634 (EC: IDA, PMID: 17167422); GO_0005654 (EC: TAS); GO_0005829 (EC: IDA, PMID: 17167422); GO_0005829 (EC: TAS); GO_0005886 (EC: TAS); GO_0006309 (EC: TAS); GO_0006508 (EC: IDA, PMID: 12888622); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0006974 (EC: IEA); GO_0007507 (EC: IEA); GO_0007605 (EC: IEA); GO_0008233 (EC: IDA, PMID: 17167422); GO_0008625 (EC: IEA); GO_0008631 (EC: IEA); GO_0008635 (EC: TAS); GO_0009411 (EC: IEA); GO_0009611 (EC: IEA); GO_0022617 (EC: TAS); GO_0030182 (EC: IBA); GO_0030198 (EC: TAS); GO_0030216 (EC: IBA); GO_0030218 (EC: IDA, PMID: 17167422); GO_0030218 (EC: TAS, PMID: 18309324); GO_0030220 (EC: TAS, PMID: 18309324); GO_0030889 (EC: IEA); GO_0034349 (EC: IEA); GO_0034612 (EC: TAS, PMID: 10521396); GO_0035329 (EC: TAS); GO_0042981 (EC: TAS); GO_0043029 (EC: IEA); GO_0043065 (EC: TAS); GO_0043066 (EC: IGI, PMID: 9353287); GO_0043281 (EC: TAS); GO_0043525 (EC: IEA); GO_0045165 (EC: IEA); GO_0045736 (EC: IEA); GO_0046007 (EC: IEA); GO_0048011 (EC: TAS); GO_0051402 (EC: IEA); GO_0097153 (EC: IMP, PMID: 10921886); GO_0097190 (EC: TAS, PMID: 10521396); GO_0097192 (EC: IEA); GO_0097193 (EC: TAS); GO_0097194 (EC: IDA, PMID: 8689682); GO_0097194 (EC: IMP, PMID: 11350920); GO_0097200 (EC: IMP, PMID: 17559062) PMID: 1067155; 7596430; 7774019; 7983002; 8044845; 8605870; 8626669; 8673606; 8689682; 8696339; 8755496; 8780721; 8804412; 8812467; 8900201; 8943232; 8962078; 8976194; 9021152; 9045680; 9108473; 9115219; 9206994; 9208847; 9219695; 9230442; 9233763; 9235961; 9252332; 9267021; 9278461; 9298992; 9323209; 9326610; 9334214; 9334240; 9334338; 9337844; 9348292; 9351817; 9353287; 9361003; 9367996; 9368003; 9384571; 9395403; 9422780; 9452471; 9525868; 9535906; 9545236; 9548463; 9593687; 9618490; 9624143; 9632733; 9660939; 9671712; 9685336; 9694885; 9705209; 9708895; 9736630; 9751706; 9786869; 9799125; 9811849; 9840926; 9850056; 9857079; 9875225; 9878167; 9894612; 9933635; 9990034; 10022118; 10066732; 10069390; 10082566; 10103059; 10200531; 10205158; 10205159; 10319819; 10364179; 10409750; 10430052; 10432301; 10435619; 10438581; 10454555; 10469173; 10479680; 10490026; 10510468; 10521396; 10556977; 10564664; 10579725; 10602493; 10602513; 10608812; 10611247; 10629060; 10671544; 10672017; 10675528; 10704341; 10708425; 10712510; 10713703; 10734073; 10748026; 10770929; 10777594; 10791974; 10799874; 10821855; 10823823; 10862606; 10896157; 10899937; 10921886; 10926122; 10942389; 10998058; 11002417; 11016947; 11024045; 11042212; 11053413; 11058115; 11076937; 11084335; 11098060; 11106668; 11123279; 11141237; 11149901; 11162250; 11162351; 11170436; 11175261; 11177389; 11222676; 11230124; 11242052; 11248093; 11257230; 11257232; 11261798; 11274152; 11278283; 11278287; 11278424; 11278572; 11278782; 11278797; 11283607; 11313965; 11331419; 11345898; 11350920; 11356849; 11359776; 11387340; 11399776; 11420704; 11423904; 11425872; 11437602; 11438643; 11447297; 11462036; 11470874; 11478781; 11479289; 11500511; 11509621; 11514563; 11517310; 11526478; 11550094; 11551979; 11555640; 11602184; 11675509; 11689006; 11696595; 11741893; 11748221; 11752060; 11752215; 11787859; 11788610; 11795487; 11802788; 11815631; 11825902; 11830582; 11832478; 11840332; 11854437; 11859414; 11866986; 11875078; 11901153; 11904443; 11927604; 11948397; 11960384; 11972398; 11981455; 11988074; 11989976; 11992386; 12004072; 12019321; 12032677; 12036886; 12044963; 12055227; 12070005; 12070657; 12080079; 12095993; 12107159; 12112012; 12118383; 12124386; 12145703; 12149654; 12150947; 12151338; 12169388; 12181128; 12181742; 12186978; 12190962; 12207967; 12210761; 12228224; 12235123; 12297281; 12390838; 12393901; 12397210; 12401855; 12404116; 12425945; 12438416; 12444137; 12477932; 12483536; 12490308; 12511568; 12515825; 12566444; 12576296; 12576443; 12579342; 12581734; 12598529; 12605885; 12606589; 12611892; 12621124; 12624662; 12643601; 12657644; 12677451; 12686427; 12700630; 12700660; 12707329; 12750393; 12750404; 12760639; 12787561; 12788227; 12788938; 12792782; 12804035; 12809603; 12821118; 12824190; 12833566; 12837287; 12854132; 12867600; 12874324; 12888622; 12897143; 14555204; 14570914; 14572611; 14612448; 14623896; 14657946; 14674699; 14678329; 14684629; 14710359; 14764700; 14960581; 14970175; 14971566; 14976035; 14982947; 14991812; 14993250; 15014070; 15015772; 15033720; 15033815; 15041704; 15087450; 15098015; 15153940; 15156398; 15178331; 15179054; 15186778; 15187159; 15200957; 15204919; 15205454; 15220451; 15241180; 15246206; 15254227; 15258591; 15280469; 15345747; 15375594; 15473998; 15489334; 15505416; 15507451; 15542841; 15564512; 15569669; 15569672; 15569692; 15578977; 15599395; 15617521; 15637055; 15638357; 15650747; 15657349; 15657356; 15670787; 15705385; 15706351; 15716280; 15725353; 15735701; 15748158; 15748808; 15767427; 15803189; 15806167; 15843892; 15848173; 15869582; 15935070; 15996160; 16009347; 16080782; 16083554; 16111829; 16120388; 16121124; 16179347; 16203739; 16204230; 16213496; 16227597; 16242324; 16286477; 16300929; 16320828; 16330530; 16337360; 16338743; 16344560; 16382148; 16455648; 16463650; 16480911; 16498457; 16501604; 16505307; 16511342; 16516911; 16520893; 16526059; 16529748; 16530181; 16530191; 16543147; 16567804; 16651613; 16689860; 16716256; 16781734; 16787777; 16791842; 16802364; 16808908; 16835231; 16869888; 16882668; 16884727; 16894574; 16897667; 16931214; 16935258; 16948902; 16949642; 16955788; 16977583; 16979168; 16983089; 17008916; 17013756; 17013758; 17023557; 17038954; 17065568; 17069460; 17071630; 17080552; 17114647; 17118559; 17121821; 17123522; 17124493; 17130234; 17140287; 17141888; 17143787; 17167422; 17172814; 17198755; 17217622; 17219053; 17235653; 17245643; 17261582; 17272816; 17283187; 17291493; 17301822; 17321792; 17324936; 17337451; 17340613; 17364171; 17379327; 17412564; 17413988; 17430778; 17436592; 17437405; 17462862; 17488272; 17495975; 17498346; 17505517; 17525639; 17534194; 17544405; 17559062; 17597071; 17606719; 17606900; 17616526; 17645689; 17653867; 17689858; 17698513; 17721932; 17724022; 17805550; 17823127; 17880920; 17908973; 17928446; 17936584; 17950632; 17967742; 17978580; 17981569; 17983802; 17989718; 18000616; 18029348; 18047842; 18054197; 18055116; 18058802; 18060501; 18074388; 18083346; 18086147; 18088367; 18092356; 18155705; 18155731; 18164959; 18171980; 18209072; 18211414; 18227733; 18256758; 18256791; 18266005; 18296636; 18297401; 18298948; 18300076; 18309324; 18330265; 18379198; 18381704; 18384375; 18415681; 18415689; 18427836; 18439040; 18441516; 18450750; 18473402; 18476631; 18521960; 18551626; 18561948; 18577580; 18585351; 18586680; 18623086; 18652315; 18658137; 18669646; 18676680; 18708163; 18712678; 18723680; 18727869; 18754867; 18759060; 18763039; 18768468; 18814044; 18818379; 18820371; 18821563; 18829519; 18838202; 18844072; 18946722; 18986328; 19013323; 19035131; 19043361; 19046417; 19052714; 19058789; 19074885; 19132366; 19141860; 19157504; 19157506; 19159073; 19170196; 19178812; 19200347; 19204086; 19219602; 19223905; 19236754; 19240112; 19241192; 19244543; 19258326; 19266703; 19269008; 19270727; 19272183; 19275584; 19275586; 19275587; 19281794; 19283487; 19289465; 19299722; 19319745; 19322201; 19351510; 19355923; 19379562; 19404232; 19414860; 19453261; 19458171; 19513559; 19519609; 19531679; 19544333; 19549685; 19550122; 19553679; 19557639; 19559790; 19567200; 19570417; 19573080; 19585117; 19598027; 19604093; 19610261; 19625176; 19626422; 19636556; 19655253; 19655254; 19655415; 19665028; 19692168; 19692467; 19698783; 19698994; 19715609; 19723039; 19724860; 19724907; 19730442; 19738422; 19759058; 19770576; 19770581; 19773279; 19774677; 19784808; 19788069; 19788411; 19807657; 19812265; 19826114; 19838207; 19840460; 19854241; 19878567; 19895210; 19913121; 19925402; 19937139; 19942343; 19956888; 19996122; 19996272; 19996275; 19996278; 20001963; 20012528; 20025478; 20038816; 20041182; 20042134; 20045442; 20060927; 20063052; 20068062; 20072652; 20085765; 20087649; 20101263; 20103643; 20104682; 20142237; 20150439; 20180022; 20198319; 20227371; 20299368; 20307198; 20340172; 20346214; 20383567; 20402676; 20404718; 20423928; 20424172; 20450729; 20453000; 20492341; 20512574; 20530714; 20566630; 20580881; 20598358; 20619728; 20628086; 20628645; 20632819; 20644561; 20661084; 20665667; 20667824; 20683021; 20683843; 20702410; 20722551; 20723300; 20738749; 20801175; 20814064; 20839416; 20855536; 20856198; 20862799; 20919853; 20929126; 20947770; 20950443; 20959405; 20962079; 20966960; 20981869; 21029675; 21048031; 21081164; 21098975; 21099290; 21099299; 21123175; 21123558; 21139048; 21142842; 21148072; 21151026; 21160486; 21178828; 21203962; 21216952; 21223758; 21237154; 21248767; 21255440; 21270757; 21307660; 21317880; 21319273; 21382445; 21441410; 21479362; 21483469; 21483669; 21484410; 21504623; 21506333; 21548803; 21555338; 21561870; 21624464; 21644054; 21644232; 21667042; 21668377; 21671484; 21682651; 21700414; 21706480; 21724551; 21725926; 21729540; 21756903; 21775054; 21785112; 21802116; 21819468; 21827945; 21859712; 21869592; 21875325; 21880013; 21890473; 21914347; 21926353; 21944661; 21959934; 21963094; 21987091; 21988832; 22013052; 22072751; 22094081; 22121772; 22136337; 22147199; 22184067; 22191568; 22216281; 22238643; 22242595; 22298410; 22302483; 22309278; 22320973; 22429811; 22429842; 22482362; 22496955; 22504224; 22541080; 22552851; 22568453; 22607239; 22629415; 22678593; 22683311; 22764223; 22796265; 22815893; 22832123; 22837201; 22844442; 22872644; 22885173; 22912727; 22926545; 22931643; 22939953; 22944165; 22949938; 22951837; 22952982; 22964638; 23000965; 23054082; 23103707; 23122728; 23152053; 23156805; 23170075; 23170789; 23220614; 23221544; 23271051; 23271418; 23295106; 23326121; 23345589; 23384723; 23386603; 23416147; 23421973; 23519117; 23531593; 23545262; 23555267; 23568731; 23591201; 23599180; 23650375; 23658722; 23686572; 23703388; 23708668; 23724505; 23765963; 23775301; 23781587; 23791066; 23846227; 23867824; 23892923; 23894522; 23900644; 23907941; 23949910; 23979166; 24009453; 24129493; 24161344; 24553140 caspase 3, apoptosis-related cysteine peptidase Ensembl:ENSG00000164305 HGNC:1504 HPRD:02799 MIM:600636 Vega:OTTHUMG00000133681 CASP3 Bin Zhao, Yue Liu, Oliver He MCH2 WEB: http://www.ncbi.nlm.nih.gov/gene CASP6 caspase 6, apoptosis-related cysteine peptidase 839 4q25 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0004197 (EC: IBA); GO_0004197 (EC: TAS); GO_0005515 (EC: IPI, PMID: 12888622); GO_0005654 (EC: TAS); GO_0005829 (EC: IDA, PMID: 17167422); GO_0005829 (EC: TAS); GO_0006508 (EC: IDA, PMID: 12888622); GO_0006915 (EC: IBA); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0008234 (EC: TAS, PMID: 7796396); GO_0030855 (EC: IEP); GO_0042802 (EC: IPI) PMID: 7796396; 7983002; 8710882; 8780721; 8812467; 8900201; 8962078; 8978814; 9219695; 9228018; 9298992; 9337844; 9463409; 9593687; 9857079; 9933635; 9990034; 10069390; 10103059; 10205159; 10409650; 10432301; 10438520; 10469173; 10481058; 10655504; 10734073; 10770929; 11016947; 11098060; 11246070; 11262188; 11331782; 11356849; 11387340; 11423904; 11438643; 11463840; 11514563; 11802788; 11832478; 11859414; 11901153; 11953316; 12052891; 12089322; 12145703; 12232792; 12477932; 12888622; 14713958; 15103018; 15200957; 15273717; 15280469; 15321985; 15356202; 15489334; 15500642; 15511269; 15654952; 15735701; 16123779; 16135563; 16169070; 16341674; 16518869; 16948818; 16977583; 17167422; 17337451; 17392160; 18029348; 18155731; 18408014; 18497562; 18723680; 18762957; 18820706; 18946722; 19022247; 19052714; 19219602; 19269008; 19414860; 19573080; 19694615; 19773279; 19897582; 19915487; 20097875; 20332099; 20402676; 20427671; 20437871; 20606168; 20661084; 20682790; 20702410; 20801175; 20855536; 20890311; 21098228; 21111746; 21139048; 21317160; 21621544; 21900206; 21906983; 21918813; 21936563; 21963094; 21988832; 22094081; 22433863; 22505724; 22683611; 22858542; 22891250; 23402898 caspase 6, apoptosis-related cysteine peptidase Ensembl:ENSG00000138794 HGNC:1507 HPRD:03321 MIM:601532 Vega:OTTHUMG00000131914 CASP6 Bin Zhao, Yue Liu, Oliver He CASP-7 CMH-1 ICE-LAP3 LICE2 MCH3 WEB: http://www.ncbi.nlm.nih.gov/gene CASP7 caspase 7, apoptosis-related cysteine peptidase 840 RP11-211N11.6 10q25 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0001836 (EC: IEA); GO_0004190 (EC: IEA); GO_0004197 (EC: IBA); GO_0004197 (EC: TAS); GO_0005515 (EC: IPI, PMID: 11084335); GO_0005634 (EC: IDA, PMID: 17167422); GO_0005654 (EC: TAS); GO_0005737 (EC: TAS, PMID: 8576161); GO_0005829 (EC: IDA, PMID: 17167422); GO_0005829 (EC: TAS); GO_0006508 (EC: IDA, PMID: 12888622); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0007507 (EC: IEA); GO_0007568 (EC: IEA); GO_0008234 (EC: TAS, PMID: 8567622); GO_0008635 (EC: TAS); GO_0009411 (EC: IEA); GO_0043525 (EC: IEA); GO_0097153 (EC: IEA); GO_0097193 (EC: TAS); GO_0097194 (EC: IBA) PMID: 1056466; 7983002; 8125298; 8521391; 8567622; 8576161; 8631895; 8755496; 8780721; 8812467; 8889548; 8962078; 9070923; 9219695; 9228018; 9230442; 9298992; 9323209; 9325343; 9337844; 9384571; 9525868; 9535906; 9593687; 9607320; 9671712; 9850056; 9875225; 9894612; 9922454; 9990034; 10069390; 10082581; 10103059; 10200531; 10318789; 10469173; 10564664; 10675528; 10731697; 10791974; 10862606; 10998058; 11016947; 11024045; 11058599; 11084335; 11170436; 11257230; 11257231; 11257232; 11278572; 11356849; 11359776; 11387340; 11399776; 11420704; 11423904; 11425872; 11448953; 11514563; 11535131; 11555640; 11752425; 11755217; 11802788; 11815631; 11829465; 11832478; 11859414; 11875078; 11904443; 11943137; 12107159; 12145703; 12181742; 12477932; 12586738; 12665508; 12804035; 12824163; 12888622; 12951057; 12970753; 14512414; 14583630; 14584591; 14623896; 14713958; 15033720; 15200957; 15254227; 15489334; 15500642; 15507451; 15511269; 15580265; 15650747; 15735701; 16123041; 16213496; 16339151; 16344560; 16385451; 16498457; 16918502; 17023557; 17094969; 17167422; 17283187; 17337451; 17504820; 17532763; 17697120; 17880920; 17978580; 18072206; 18086147; 18459962; 18521960; 18596415; 18708163; 18723680; 18785314; 19022247; 19052714; 19058873; 19141860; 19219602; 19241192; 19258326; 19269008; 19323650; 19414860; 19531679; 19573080; 19581639; 19604093; 19605487; 19617626; 19655253; 19655254; 19692467; 19698783; 19738422; 19759058; 19770576; 19773279; 19782763; 19826114; 19913121; 19996278; 20159985; 20379614; 20402676; 20404718; 20453000; 20468060; 20566630; 20567846; 20628086; 20661084; 20800603; 20819778; 20855536; 20950443; 20959405; 21044950; 21142842; 21157428; 21484410; 21555521; 21936563; 22184066; 22441531; 22451931; 22548721; 22561518; 22584050; 22863883; 22986525; 23000965; 23190606; 23383273; 23650375; 23765963; 23979166 caspase 7, apoptosis-related cysteine peptidase Ensembl:ENSG00000165806 HGNC:1508 HPRD:03457 MIM:601761 Vega:OTTHUMG00000019076 CASP7 Bin Zhao, Yue Liu, Oliver He ALPS2B CAP4 Casp-8 FLICE MACH MCH5 WEB: http://www.ncbi.nlm.nih.gov/gene CASP8 caspase 8, apoptosis-related cysteine peptidase 841 2q33-q34 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0001525 (EC: IEA); GO_0001841 (EC: IEA); GO_0002020 (EC: IPI); GO_0002224 (EC: TAS); GO_0002756 (EC: TAS); GO_0004197 (EC: IDA, PMID: 19240112); GO_0004197 (EC: TAS); GO_0005164 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10442631); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005739 (EC: IDA); GO_0005741 (EC: TAS); GO_0005815 (EC: IDA); GO_0005829 (EC: IDA, PMID: 17167422); GO_0005829 (EC: TAS); GO_0005856 (EC: TAS, PMID: 10891503); GO_0006508 (EC: IDA, PMID: 12888622); GO_0006915 (EC: IGI, PMID: 17599062); GO_0006915 (EC: IMP); GO_0006915 (EC: TAS); GO_0006919 (EC: TAS); GO_0006921 (EC: TAS); GO_0007507 (EC: IEA); GO_0008233 (EC: IMP, PMID: 17047155); GO_0008234 (EC: TAS, PMID: 8681376); GO_0008625 (EC: IBA); GO_0009409 (EC: IEA); GO_0016032 (EC: IEA); GO_0030101 (EC: TAS, PMID: 18309324); GO_0030225 (EC: TAS, PMID: 18309324); GO_0030690 (EC: IEA); GO_0031264 (EC: IDA, PMID: 11101870); GO_0031265 (EC: IDA, PMID: 11717445); GO_0031625 (EC: IPI, PMID: 15069192); GO_0032025 (EC: IEA); GO_0032355 (EC: IEA); GO_0032496 (EC: IEA); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034612 (EC: IMP, PMID: 10521396); GO_0035666 (EC: TAS); GO_0035872 (EC: TAS); GO_0035877 (EC: IPI, PMID: 11717445); GO_0042110 (EC: TAS, PMID: 18309324); GO_0042113 (EC: TAS, PMID: 18309324); GO_0043005 (EC: IEA); GO_0043123 (EC: IEP, PMID: 12761501); GO_0043123 (EC: IMP, PMID: 12884866); GO_0043124 (EC: IMP, PMID: 17047155); GO_0044297 (EC: IEA); GO_0045087 (EC: TAS); GO_0045121 (EC: IEA); GO_0045471 (EC: IEA); GO_0045651 (EC: IMP, PMID: 17047155); GO_0045862 (EC: IDA, PMID: 18387192); GO_0046677 (EC: IEA); GO_0051291 (EC: IEA); GO_0051603 (EC: IMP, PMID: 10521396); GO_0060715 (EC: TAS, PMID: 18309324); GO_0070243 (EC: IEA); GO_0070423 (EC: TAS); GO_0071260 (EC: IEP, PMID: 19593445); GO_0071407 (EC: IEA); GO_0097153 (EC: IMP); GO_0097190 (EC: IMP, PMID: 11101870); GO_0097190 (EC: TAS); GO_0097191 (EC: IDA); GO_0097193 (EC: TAS); GO_0097194 (EC: IMP); GO_0097199 (EC: IMP, PMID: 11717445); GO_0097202 (EC: IDA, PMID: 18387192); GO_0097284 (EC: IEA); GO_0097342 (EC: IDA); GO_1900740 (EC: TAS); GO_2001238 (EC: IEA); GO_2001239 (EC: TAS) PMID: 170210; 3031469; 7983002; 8521391; 8681376; 8681377; 8755496; 8962078; 9006941; 9027312; 9184224; 9208847; 9219695; 9228018; 9271594; 9289491; 9325248; 9326610; 9334338; 9337844; 9380701; 9535906; 9539746; 9560245; 9575181; 9624166; 9632733; 9721089; 9727491; 9727492; 9763668; 9774341; 9792675; 9804161; 9875225; 9878167; 9931493; 9971775; 9990034; 10069390; 10235259; 10329646; 10432301; 10435619; 10438581; 10442631; 10469173; 10493725; 10508784; 10521396; 10616217; 10708425; 10716992; 10734073; 10860845; 10891503; 10894160; 10911620; 10926122; 10964557; 11000244; 11002417; 11016947; 11048727; 11085743; 11098060; 11101867; 11101870; 11102441; 11161814; 11177389; 11181075; 11260720; 11264300; 11340079; 11387340; 11395500; 11406564; 11420686; 11423904; 11431480; 11437602; 11479289; 11514563; 11555640; 11583996; 11683038; 11684016; 11717445; 11733517; 11734564; 11735112; 11741396; 11741985; 11751056; 11751897; 11752160; 11772515; 11788820; 11832478; 11865194; 11877293; 11917123; 11933563; 11940602; 11965497; 11992615; 12010809; 12021264; 12037669; 12041673; 12052891; 12065591; 12095993; 12096338; 12097160; 12107159; 12107169; 12122017; 12131184; 12170765; 12189238; 12191471; 12196516; 12198154; 12215447; 12218097; 12220669; 12232792; 12353035; 12393901; 12404116; 12438416; 12477932; 12496481; 12496482; 12507932; 12527898; 12598529; 12620239; 12646168; 12668660; 12692130; 12700635; 12700660; 12702723; 12707329; 12721308; 12738800; 12748179; 12750393; 12750404; 12753742; 12754217; 12761501; 12765336; 12804595; 12841868; 12884866; 12887920; 12888622; 12911633; 12912912; 12960156; 13679856; 14522966; 14560027; 14584591; 14625033; 14644092; 14644197; 14684825; 14688019; 14701762; 14713958; 14759258; 14970175; 14982875; 14982947; 14991747; 14993214; 15015772; 15024054; 15034549; 15067048; 15069192; 15111130; 15142380; 15159409; 15205454; 15210716; 15254227; 15262979; 15280356; 15289853; 15369772; 15383280; 15388581; 15389560; 15390286; 15473998; 15476874; 15489334; 15492869; 15507451; 15507484; 15509781; 15531912; 15578977; 15592455; 15592525; 15601643; 15611097; 15637055; 15640164; 15645452; 15650242; 15659383; 15701651; 15717329; 15735701; 15735742; 15746428; 15760909; 15782135; 15815621; 15849201; 15906362; 15956881; 15976052; 16036110; 16135563; 16169070; 16179347; 16179941; 16183855; 16186808; 16193064; 16225956; 16227629; 16242324; 16251207; 16344560; 16374545; 16397500; 16436380; 16446372; 16478725; 16497673; 16528386; 16538383; 16541419; 16556893; 16607283; 16619028; 16633737; 16636047; 16722146; 16733806; 16762833; 16886176; 16920630; 16936772; 16938569; 16951203; 17018785; 17030903; 17047155; 17064406; 17071630; 17159907; 17167422; 17170703; 17182797; 17224200; 17272309; 17283187; 17290218; 17293864; 17314102; 17337451; 17378240; 17436592; 17442709; 17450141; 17488272; 17525260; 17532763; 17534194; 17545522; 17572490; 17585337; 17599062; 17616526; 17623017; 17626072; 17627287; 17653867; 17666167; 17684142; 17726263; 17891485; 17911615; 17932347; 17940865; 18029348; 18045865; 18054197; 18076022; 18086677; 18089778; 18089800; 18097748; 18158779; 18161513; 18216014; 18245485; 18305469; 18309324; 18324486; 18328427; 18343995; 18362937; 18381704; 18387192; 18398042; 18431743; 18455983; 18458084; 18473402; 18483392; 18485876; 18516683; 18563783; 18570872; 18596409; 18603835; 18617900; 18625728; 18632964; 18675369; 18676680; 18676836; 18684943; 18691973; 18716417; 18725521; 18728974; 18776134; 18796435; 18823309; 18823701; 18840411; 18974049; 19001123; 19013323; 19048023; 19048627; 19060883; 19074885; 19094228; 19111387; 19112091; 19115040; 19122169; 19124506; 19125371; 19141860; 19152111; 19160091; 19166881; 19170196; 19176810; 19203830; 19214542; 19214744; 19219602; 19239323; 19240112; 19258216; 19260109; 19269008; 19275584; 19275586; 19276244; 19289465; 19318553; 19343040; 19345995; 19372376; 19373245; 19412632; 19414860; 19427028; 19432816; 19453261; 19470771; 19492233; 19493480; 19521670; 19528225; 19531679; 19542541; 19543235; 19550122; 19573080; 19593445; 19597472; 19617217; 19625176; 19629679; 19644511; 19665028; 19684859; 19692168; 19692467; 19698994; 19710364; 19738422; 19770581; 19773279; 19773432; 19778795; 19795398; 19801665; 19807657; 19812265; 19826114; 19843670; 19852930; 19854135; 19902255; 19913121; 19923319; 19954364; 19996275; 20005201; 20012528; 20013803; 20033750; 20033885; 20044137; 20080300; 20085538; 20086182; 20087649; 20132554; 20143425; 20145138; 20150972; 20176653; 20198319; 20237344; 20301425; 20308068; 20353946; 20356928; 20363033; 20379197; 20398055; 20402676; 20403046; 20404718; 20443055; 20448643; 20453000; 20471133; 20502973; 20554749; 20564345; 20565257; 20572163; 20605201; 20606168; 20613771; 20616437; 20628086; 20644561; 20652397; 20661084; 20671745; 20677014; 20702410; 20724831; 20799830; 20800603; 20802294; 20804486; 20808443; 20811726; 20817393; 20819778; 20825417; 20829884; 20855536; 20870287; 20877624; 20937773; 20951133; 20959405; 20972266; 20978129; 20978178; 21048031; 21072056; 21104989; 21107701; 21135236; 21139048; 21153367; 21157428; 21166494; 21178828; 21183680; 21183955; 21248767; 21282461; 21328377; 21380726; 21396853; 21419663; 21426305; 21436691; 21444671; 21454681; 21458669; 21461653; 21483669; 21487429; 21524651; 21525013; 21538054; 21548803; 21554547; 21569377; 21576355; 21620750; 21628531; 21633787; 21667042; 21669575; 21697465; 21704196; 21714991; 21724551; 21737329; 21751259; 21785112; 21785459; 21801448; 21803845; 21816816; 21819468; 21822306; 21865223; 21868312; 21900206; 21906983; 21979465; 21983787; 21988832; 22010212; 22027693; 22037414; 22056502; 22094081; 22120515; 22160860; 22179575; 22211869; 22253841; 22266862; 22267217; 22274400; 22297296; 22322857; 22339913; 22357491; 22383778; 22408249; 22421964; 22508042; 22513478; 22528489; 22585859; 22588838; 22632162; 22644571; 22659694; 22672670; 22683265; 22683266; 22691345; 22801217; 22806078; 22815944; 22820578; 22843554; 22860893; 22864571; 22922291; 22949938; 22971934; 23071110; 23081800; 23096115; 23142077; 23185580; 23230268; 23244104; 23255602; 23289213; 23306557; 23313206; 23418437; 23434145; 23618862; 23659359; 23751956; 23770605; 23844036; 23921907; 23972990; 23982205; 24021263; 24121507; 24391214 caspase 8, apoptosis-related cysteine peptidase Ensembl:ENSG00000064012 HGNC:1509 HPRD:03459 MIM:601763 Vega:OTTHUMG00000132821 CASP8 Bin Zhao, Yue Liu, Oliver He APAF-3 APAF3 ICE-LAP6 MCH6 PPP1R56 WEB: http://www.ncbi.nlm.nih.gov/gene CASP9 caspase 9, apoptosis-related cysteine peptidase 842 RP11-265F14.3 1p36.21 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0004197 (EC: IBA); GO_0005515 (EC: IPI, PMID: 10206961); GO_0005634 (EC: IEA); GO_0005739 (EC: IEA); GO_0005829 (EC: IDA, PMID: 17167422); GO_0005829 (EC: TAS); GO_0006915 (EC: TAS, PMID: 8663294); GO_0006974 (EC: IDA, PMID: 15657060); GO_0007173 (EC: TAS); GO_0007568 (EC: IEA); GO_0008047 (EC: TAS, PMID: 9390557); GO_0008233 (EC: IDA); GO_0008543 (EC: TAS); GO_0008630 (EC: IMP, PMID: 15657060); GO_0008635 (EC: TAS); GO_0017124 (EC: IDA, PMID: 15657060); GO_0019901 (EC: IDA, PMID: 15657060); GO_0030220 (EC: TAS, PMID: 18309324); GO_0032025 (EC: IEA); GO_0032355 (EC: IEA); GO_0032496 (EC: IEA); GO_0034349 (EC: IEA); GO_0034644 (EC: IDA, PMID: 15657060); GO_0038095 (EC: TAS); GO_0042770 (EC: IDA, PMID: 15657060); GO_0042981 (EC: TAS); GO_0043065 (EC: TAS); GO_0043293 (EC: IDA); GO_0043525 (EC: IEA); GO_0045087 (EC: TAS); GO_0046677 (EC: IEA); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0071549 (EC: IEA); GO_0097193 (EC: TAS); GO_2001020 (EC: IMP, PMID: 15657060) PMID: 1067155; 7983002; 8663294; 8900201; 8962078; 9323209; 9337844; 9390557; 9488720; 9539746; 9545235; 9651578; 9671712; 9812896; 9837928; 9878060; 9890966; 9922454; 9990849; 10070954; 10085063; 10187815; 10206961; 10329646; 10376594; 10384055; 10438581; 10469173; 10671558; 10708425; 11024045; 11069302; 11076957; 11084335; 11113115; 11230124; 11242052; 11248093; 11350957; 11387340; 11390657; 11393657; 11408476; 11423904; 11462036; 11514563; 11734640; 11801602; 11801603; 11803376; 11832478; 11870543; 11905052; 11919192; 11927604; 11948397; 12021264; 12055227; 12095993; 12096338; 12145703; 12147322; 12372609; 12393263; 12393884; 12404116; 12477932; 12566444; 12586738; 12620238; 12620239; 12637514; 12732844; 12749848; 12782307; 12792650; 12804035; 12914932; 12954616; 14512414; 14523016; 14566819; 14634335; 14684629; 14701803; 14747474; 14982875; 14991812; 14993223; 15200957; 15214043; 15220451; 15254227; 15262985; 15273730; 15280366; 15300255; 15473998; 15485395; 15485396; 15489334; 15500642; 15507451; 15578977; 15629764; 15657060; 15657349; 15674327; 15703181; 15725353; 15735701; 15749826; 15767427; 15811855; 15829969; 15935070; 16038259; 16120388; 16181301; 16242324; 16260615; 16287866; 16300929; 16322207; 16337360; 16339151; 16344560; 16480911; 16497673; 16505307; 16505493; 16511342; 16520893; 16687442; 16689829; 16701639; 16710414; 16716256; 16780893; 16895904; 16936772; 16979168; 17030903; 17071630; 17079734; 17140287; 17167422; 17179183; 17207965; 17285546; 17291493; 17299206; 17379327; 17409234; 17437405; 17466630; 17534194; 17626072; 17653867; 17893147; 17899380; 17967742; 18022362; 18054197; 18083711; 18086147; 18202770; 18297401; 18309324; 18381704; 18415681; 18632964; 18676680; 18723680; 18813792; 18814044; 18840411; 19013323; 19016842; 19052714; 19058789; 19074885; 19081073; 19141860; 19153467; 19159073; 19170196; 19183163; 19219602; 19238172; 19269008; 19275583; 19275584; 19275586; 19275587; 19359048; 19412632; 19414860; 19458171; 19465923; 19493480; 19550122; 19573080; 19625176; 19626422; 19655415; 19674438; 19692168; 19692467; 19698783; 19724860; 19741144; 19758996; 19770581; 19773279; 19789190; 19807657; 19826114; 19895210; 19906200; 19913121; 20012528; 20013803; 20022954; 20042134; 20060927; 20071584; 20227371; 20227384; 20340172; 20357690; 20379614; 20402676; 20404718; 20453000; 20490276; 20628086; 20644561; 20650551; 20661084; 20667824; 20800603; 20804486; 20855536; 20887385; 20959405; 20978129; 21045158; 21048031; 21091209; 21117896; 21142842; 21178828; 21266831; 21282934; 21284734; 21297999; 21382445; 21396853; 21461653; 21483669; 21538054; 21555338; 21565459; 21612408; 21622622; 21644232; 21659556; 21724551; 21757755; 21785112; 21827945; 21868008; 21869827; 21944661; 21957492; 21988832; 22086301; 22120515; 22191568; 22219640; 22306364; 22339913; 22552851; 22573662; 22616010; 22629415; 22679284; 22683311; 22926545; 22944165; 22974165; 22981751; 23038270; 23303631; 23383273; 23396972; 23424205; 23430060; 23443079; 23539542; 23566959; 23572523; 23615977; 23637769; 23645041; 23652278; 23678002; 23725396; 23867824; 24121507; 24161344; 24346702 caspase 9, apoptosis-related cysteine peptidase Ensembl:ENSG00000132906 HGNC:1511 HPRD:03756 MIM:602234 Vega:OTTHUMG00000002256 CASP9 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene CAT catalase 847 11p13 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0000302 (EC: IMP, PMID: 16644728); GO_0001657 (EC: IEA); GO_0001666 (EC: IEA); GO_0001822 (EC: IEA); GO_0004046 (EC: IEA); GO_0004096 (EC: IDA, PMID: 16644728); GO_0004096 (EC: TAS); GO_0005102 (EC: IPI); GO_0005758 (EC: IEA); GO_0005764 (EC: IEA); GO_0005777 (EC: IDA, PMID: 18379038); GO_0005778 (EC: ISS); GO_0005782 (EC: TAS); GO_0005783 (EC: IEA); GO_0005794 (EC: IEA); GO_0005829 (EC: IEA); GO_0005886 (EC: IEA); GO_0006144 (EC: TAS); GO_0006195 (EC: TAS); GO_0006641 (EC: IEA); GO_0008203 (EC: IEA); GO_0009060 (EC: IEA); GO_0009650 (EC: IMP, PMID: 16644728); GO_0014068 (EC: IEA); GO_0016209 (EC: IDA, PMID: 10514471); GO_0016684 (EC: ISS); GO_0019899 (EC: IPI, PMID: 16781659); GO_0020027 (EC: IEA); GO_0020037 (EC: IDA, PMID: 10656833); GO_0032088 (EC: IEA); GO_0033197 (EC: IEA); GO_0042697 (EC: IEA); GO_0042744 (EC: IDA, PMID: 18379038); GO_0042803 (EC: IDA, PMID: 10656833); GO_0043066 (EC: IMP, PMID: 16644728); GO_0043231 (EC: IDA); GO_0044281 (EC: TAS); GO_0046872 (EC: IEA); GO_0050661 (EC: IDA, PMID: 10656833); GO_0051092 (EC: IEA); GO_0051262 (EC: IDA, PMID: 10656833); GO_0051289 (EC: IDA); GO_0051781 (EC: IEA); GO_0055086 (EC: TAS); GO_0055093 (EC: IEA); GO_0071363 (EC: IEA) PMID: 1551654; 2268310; 2308162; 2991908; 3755525; 3755526; 3944256; 6252821; 6548744; 7829101; 8282800; 8479912; 9818873; 9848047; 10096042; 10488055; 10514471; 10567208; 10567403; 10656833; 10666617; 10960480; 11106583; 11134921; 11182520; 11313354; 11479740; 11728823; 11729237; 11837458; 11907164; 12032677; 12110367; 12165738; 12231449; 12372460; 12447480; 12468545; 12469627; 12477932; 12487379; 12516882; 12603857; 12606529; 12665801; 12730222; 12777400; 12824748; 12838770; 12950161; 13904105; 14580687; 14710363; 14962975; 14975589; 15125229; 15131792; 15133753; 15182856; 15203188; 15472150; 15489334; 15528999; 15556604; 15705913; 15733034; 15735318; 15774926; 15800961; 15870505; 15934434; 15988600; 16026777; 16047490; 16076760; 16098030; 16192345; 16204228; 16236267; 16298864; 16385446; 16387755; 16424062; 16453382; 16467073; 16482509; 16504657; 16523188; 16554811; 16586065; 16600249; 16630078; 16644728; 16729966; 16773213; 16775184; 16781659; 16868544; 16956821; 17005595; 17053817; 17145829; 17171548; 17209132; 17213227; 17264407; 17548672; 17549373; 17566139; 17567676; 17567781; 17577741; 17601350; 17634480; 17646900; 17693525; 17696155; 17850515; 17879952; 17937824; 18048809; 18171680; 18248894; 18312938; 18353692; 18368408; 18379038; 18415766; 18423055; 18469277; 18483329; 18485895; 18606005; 18634817; 18682580; 18781797; 18930811; 18936436; 18949620; 18977241; 19050255; 19064360; 19092850; 19124506; 19170196; 19172437; 19242068; 19254215; 19255063; 19274593; 19336475; 19341793; 19373626; 19399816; 19409565; 19424819; 19479899; 19497990; 19505917; 19538885; 19584075; 19615732; 19622717; 19625176; 19688952; 19692168; 19705749; 19731237; 19787204; 19855359; 19863340; 19874574; 19896490; 19897513; 19897742; 19902075; 19913121; 19929244; 19949914; 20020532; 20049130; 20078877; 20082261; 20097730; 20105444; 20109103; 20110814; 20178365; 20194081; 20301895; 20416077; 20444272; 20485444; 20494887; 20613769; 20628086; 20643115; 20649881; 20727719; 20732340; 20851292; 20878976; 20923778; 21053180; 21054578; 21054877; 21069346; 21083503; 21109199; 21131394; 21139048; 21179281; 21180245; 21191398; 21295602; 21417634; 21689642; 21799178; 21827848; 21829032; 21832049; 21890473; 21906983; 21921984; 21947853; 21964540; 21968610; 21976670; 21985133; 21985966; 21988832; 22002062; 22058000; 22089180; 22108257; 22167619; 22242279; 22286031; 22465269; 22556393; 22645453; 22736749; 22880027; 22907559; 22939629; 22958044; 22959522; 22970972; 22998821; 23066387; 23098659; 23212700; 23325794; 23340375; 23390647; 23425094; 23461612; 23746122; 23771908; 23773345; 23911407; 23961996 catalase CAT Bin Zhao, Yue Liu, Oliver He BSCL3 CGL3 MSTP085 PPH3 VIP21 WEB: http://www.ncbi.nlm.nih.gov/gene CAV1 caveolin 1, caveolae protein, 22kDa 857 7q31.1 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0000122 (EC: ISS); GO_0000139 (EC: IDA, PMID: 11294831); GO_0000139 (EC: TAS); GO_0000165 (EC: IEA); GO_0000188 (EC: ISS); GO_0001525 (EC: IEA); GO_0001570 (EC: ISS); GO_0001666 (EC: ISS); GO_0001937 (EC: ISS); GO_0001960 (EC: IEA); GO_0002080 (EC: IEA); GO_0002931 (EC: IEA); GO_0003057 (EC: IEA); GO_0005102 (EC: IPI, PMID: 16890161); GO_0005113 (EC: NAS, PMID: 11278759); GO_0005198 (EC: IDA, PMID: 11865038); GO_0005515 (EC: IPI, PMID: 11075810); GO_0005622 (EC: IDA, PMID: 15703204); GO_0005768 (EC: IDA); GO_0005783 (EC: IDA, PMID: 11294831); GO_0005811 (EC: TAS); GO_0005886 (EC: IDA); GO_0005886 (EC: TAS); GO_0005887 (EC: IEA); GO_0005901 (EC: IDA, PMID: 15219854); GO_0005901 (EC: NAS, PMID: 15657086); GO_0005929 (EC: IEA); GO_0005938 (EC: IEA); GO_0006641 (EC: ISS); GO_0006816 (EC: ISS); GO_0006874 (EC: ISS); GO_0006940 (EC: ISS); GO_0007519 (EC: ISS); GO_0007595 (EC: IEA); GO_0007596 (EC: TAS); GO_0008104 (EC: ISS); GO_0009267 (EC: IEP, PMID: 15657086); GO_0010524 (EC: ISS, PMID: 19052258); GO_0015485 (EC: TAS, PMID: 11294831); GO_0016032 (EC: IEA); GO_0016050 (EC: IDA, PMID: 12743374); GO_0016323 (EC: IDA, PMID: 16904002); GO_0016324 (EC: IDA, PMID: 16904002); GO_0016504 (EC: ISS); GO_0019217 (EC: ISS); GO_0019899 (EC: IPI); GO_0019915 (EC: ISS); GO_0030193 (EC: IMP, PMID: 17848177); GO_0030301 (EC: TAS, PMID: 11294831); GO_0030514 (EC: IDA, PMID: 15657086); GO_0030666 (EC: TAS); GO_0030857 (EC: ISS); GO_0030879 (EC: ISS); GO_0031295 (EC: IDA, PMID: 17287217); GO_0031397 (EC: IMP); GO_0031410 (EC: IDA, PMID: 19931615); GO_0032091 (EC: IDA, PMID: 16890161); GO_0032507 (EC: ISS); GO_0032570 (EC: IDA, PMID: 12388746); GO_0032947 (EC: TAS, PMID: 19052258); GO_0033137 (EC: IDA, PMID: 18081315); GO_0033138 (EC: IDA, PMID: 18081315); GO_0033484 (EC: ISS); GO_0042310 (EC: IEA); GO_0042524 (EC: IEA); GO_0042632 (EC: ISS); GO_0042632 (EC: TAS, PMID: 11294831); GO_0043234 (EC: IEA); GO_0043409 (EC: ISS); GO_0043627 (EC: IDA, PMID: 12388746); GO_0044281 (EC: TAS); GO_0045019 (EC: ISS); GO_0045121 (EC: IDA, PMID: 11294831); GO_0045907 (EC: ISS); GO_0046209 (EC: TAS); GO_0046426 (EC: ISS); GO_0048471 (EC: IDA, PMID: 19931615); GO_0048471 (EC: ISS); GO_0048550 (EC: IMP); GO_0048554 (EC: ISS); GO_0050900 (EC: TAS); GO_0050998 (EC: IPI, PMID: 12852865); GO_0050999 (EC: TAS); GO_0051001 (EC: IEA); GO_0051260 (EC: ISS); GO_0051480 (EC: IDA, PMID: 19052258); GO_0051592 (EC: ISS, PMID: 19052258); GO_0051899 (EC: ISS); GO_0052547 (EC: ISS); GO_0055074 (EC: ISS); GO_0060056 (EC: ISS); GO_0070836 (EC: IMP, PMID: 12633858); GO_0071455 (EC: IMP); GO_0072584 (EC: IDA, PMID: 19931615); GO_0090090 (EC: ISS); GO_0090263 (EC: IMP, PMID: 16890161); GO_0097190 (EC: IMP); GO_2000286 (EC: IMP, PMID: 16890161); GO_2000811 (EC: IMP); GO_2001238 (EC: IMP); GO_2001244 (EC: IMP) PMID: 1294831; 1360410; 8058322; 8619474; 8621645; 8632005; 8910295; 8910575; 9110174; 9188442; 9252391; 9361015; 9374534; 9380697; 9553108; 9580552; 9647788; 9662443; 9685399; 9741627; 9801158; 9837809; 9867838; 10066366; 10085129; 10086342; 10087206; 10090765; 10212252; 10218480; 10598578; 10637311; 10675563; 10781589; 10921915; 10980191; 10988071; 11039464; 11075810; 11076863; 11078729; 11102446; 11112773; 11114180; 11238032; 11256614; 11278309; 11278759; 11294831; 11339822; 11425855; 11432874; 11451957; 11498016; 11546661; 11563969; 11563984; 11707266; 11724572; 11748236; 11751885; 11805080; 11845324; 11865038; 11866528; 11915322; 11920460; 11956154; 11980479; 12011038; 12122055; 12138116; 12147258; 12176037; 12185081; 12186899; 12235142; 12354760; 12359771; 12368209; 12372346; 12388423; 12388746; 12401329; 12414512; 12414992; 12429840; 12477932; 12507501; 12529448; 12562842; 12606314; 12633858; 12648214; 12690205; 12694195; 12711000; 12716887; 12730243; 12732636; 12737162; 12743374; 12753742; 12810205; 12813462; 12816877; 12852865; 12888893; 14576164; 14593097; 14612902; 14645548; 14660607; 14665433; 14675200; 14706341; 14707126; 14719121; 14729661; 14963033; 14981899; 15003536; 15064242; 15069532; 15182174; 15190056; 15201341; 15205342; 15219854; 15230350; 15234566; 15234575; 15240128; 15242332; 15263006; 15274335; 15314095; 15334058; 15353589; 15375584; 15458387; 15466865; 15466889; 15485671; 15485672; 15489334; 15489336; 15496150; 15498565; 15504729; 15531587; 15539149; 15590415; 15592455; 15592498; 15657086; 15665033; 15691837; 15703204; 15722199; 15769846; 15782218; 15811424; 15817451; 15948133; 15951569; 15958730; 15968725; 15969750; 16107720; 16202996; 16225848; 16244790; 16251425; 16263077; 16324201; 16328005; 16332692; 16338968; 16344560; 16381901; 16405917; 16407214; 16443388; 16480767; 16501093; 16541313; 16601146; 16601841; 16608879; 16616146; 16617096; 16713605; 16722822; 16723714; 16790997; 16799092; 16807357; 16820915; 16822931; 16850311; 16857240; 16870193; 16877379; 16890161; 16897435; 16904002; 16920641; 16931572; 16951145; 16979166; 17010968; 17014845; 17047056; 17081983; 17111160; 17178917; 17179151; 17190831; 17192395; 17197700; 17200343; 17202321; 17237399; 17245131; 17255364; 17272740; 17284246; 17287217; 17299799; 17314510; 17334644; 17341888; 17359972; 17379346; 17460461; 17478448; 17502619; 17537407; 17556531; 17594718; 17609206; 17615539; 17626097; 17662641; 17671707; 17699771; 17707459; 17713785; 17785436; 17786288; 17803693; 17848177; 17850762; 17851687; 17855368; 17898556; 17906498; 17933968; 17935714; 17936759; 17942630; 17952758; 18053095; 18054388; 18065769; 18081315; 18162583; 18180853; 18203815; 18211975; 18218624; 18237401; 18245088; 18258603; 18282163; 18296864; 18300018; 18301242; 18308897; 18312604; 18332144; 18406871; 18434090; 18437015; 18439424; 18444242; 18458534; 18510854; 18543249; 18561140; 18596970; 18598695; 18635971; 18667513; 18667611; 18676680; 18681962; 18698612; 18759267; 18789131; 18793348; 18802406; 18836420; 18922892; 18923542; 18936967; 18957516; 18985008; 18992284; 18992712; 19002186; 19002697; 19010547; 19015640; 19032226; 19038362; 19052258; 19059381; 19061949; 19104007; 19116988; 19121286; 19123976; 19160064; 19170196; 19219452; 19234134; 19244345; 19250636; 19286607; 19288272; 19342880; 19369293; 19381331; 19386787; 19395651; 19411448; 19411449; 19434519; 19446582; 19475601; 19477952; 19483189; 19483462; 19487814; 19494002; 19499152; 19521982; 19556867; 19581923; 19582878; 19595769; 19609943; 19614762; 19614763; 19620302; 19625176; 19641024; 19679565; 19692168; 19706615; 19716156; 19718657; 19718715; 19759399; 19767411; 19787257; 19801678; 19816600; 19820694; 19828204; 19846513; 19887621; 19893453; 19897728; 19913121; 19930645; 19931615; 19948975; 19960513; 19965594; 20021823; 20031158; 20062060; 20062063; 20127227; 20153318; 20177058; 20187291; 20209490; 20345844; 20346360; 20371787; 20374325; 20392844; 20395445; 20411337; 20427576; 20460433; 20463894; 20543983; 20558341; 20581046; 20605793; 20610713; 20624795; 20628086; 20629037; 20646460; 20700465; 20729193; 20736308; 20810358; 20819483; 20819778; 20826780; 20835238; 20835266; 20842066; 20855565; 20881564; 20923773; 20940300; 20977883; 21039037; 21041450; 21074769; 21098633; 21106507; 21109942; 21133631; 21139048; 21148404; 21152401; 21165568; 21199324; 21246406; 21302621; 21321670; 21335944; 21340433; 21372166; 21373757; 21378366; 21382479; 21416157; 21430048; 21440420; 21445970; 21471610; 21473727; 21514437; 21521946; 21551225; 21584795; 21585620; 21609392; 21611203; 21613355; 21683457; 21690289; 21693152; 21701559; 21704113; 21715681; 21729786; 21761200; 21789897; 21803870; 21804187; 21822278; 21840940; 21841821; 21861625; 21873608; 21882259; 21890473; 21901744; 21906983; 21909981; 21918362; 21925842; 21949119; 21951852; 21965771; 21965789; 21976276; 22038047; 22041584; 22057638; 22072235; 22075971; 22095627; 22127416; 22128235; 22134245; 22142403; 22152020; 22159333; 22194465; 22200856; 22201996; 22215724; 22230296; 22236542; 22238363; 22240009; 22241747; 22275353; 22277251; 22277751; 22287735; 22316086; 22323292; 22353223; 22353809; 22370641; 22378247; 22395498; 22402147; 22411794; 22433870; 22454521; 22474125; 22474227; 22484374; 22502704; 22506673; 22513979; 22528500; 22544366; 22547061; 22547813; 22564243; 22571278; 22575653; 22593443; 22659071; 22674854; 22693251; 22706202; 22730441; 22745744; 22748181; 22772753; 22807396; 22824620; 22883195; 22883991; 22894556; 22898083; 22931092; 22936677; 22939629; 22952906; 23000965; 23004679; 23056496; 23067370; 23114650; 23117935; 23128390; 23139255; 23206456; 23228128; 23262137; 23267770; 23280667; 23283514; 23300727; 23302227; 23333919; 23335559; 23352616; 23383114; 23393366; 23404184; 23428975; 23442759; 23460862; 23463606; 23482776; 23527097; 23580180; 23580232; 23583521; 23598719; 23598720; 23603343; 23606537; 23637463; 23645736; 23653359; 23717204; 23723060; 23723070; 23729330; 23736812; 23742006; 23743525; 23845778; 23894397; 23907124; 23963167; 24089527; 24211445; 24222128; 24572674 caveolin 1, caveolae protein, 22kDa Ensembl:ENSG00000105974 HGNC:1527 HPRD:03028 MIM:601047 Vega:OTTHUMG00000023413 CAV1 Bin Zhao, Yue Liu, Oliver He HIP4 WEB: http://www.ncbi.nlm.nih.gov/gene CBS cystathionine-beta-synthase 875 21q22.3 20140408 9606 21 protein-coding Official from a nomenclature committee GO_0000096 (EC: TAS); GO_0001958 (EC: IEA); GO_0001974 (EC: IEA); GO_0004122 (EC: IDA, PMID: 18776696); GO_0004122 (EC: TAS); GO_0005515 (EC: IPI, PMID: 17087506); GO_0005634 (EC: IDA, PMID: 17087506); GO_0005829 (EC: IDA, PMID: 16780588); GO_0005829 (EC: TAS); GO_0006535 (EC: IEA); GO_0006563 (EC: IDA, PMID: 19010420); GO_0006565 (EC: IDA, PMID: 18776696); GO_0006801 (EC: IEA); GO_0019343 (EC: IEA); GO_0019346 (EC: TAS); GO_0019448 (EC: IDA, PMID: 15520012); GO_0019899 (EC: IPI, PMID: 17087506); GO_0020037 (EC: IDA, PMID: 7929220); GO_0020037 (EC: IMP, PMID: 18776696); GO_0021587 (EC: IEA); GO_0030170 (EC: IDA, PMID: 18776696); GO_0030554 (EC: IEA); GO_0030823 (EC: IEA); GO_0031625 (EC: IPI, PMID: 17087506); GO_0034641 (EC: TAS); GO_0042802 (EC: IPI, PMID: 16189514); GO_0042803 (EC: IDA, PMID: 11483494); GO_0043066 (EC: IEA); GO_0043418 (EC: IDA, PMID: 18776696); GO_0043506 (EC: IEA); GO_0044281 (EC: TAS); GO_0046872 (EC: IEA); GO_0050667 (EC: IDA, PMID: 19010420); GO_0050880 (EC: IEA); GO_0051593 (EC: IEA); GO_0060135 (EC: IEA); GO_0060351 (EC: IEA); GO_0070814 (EC: IDA, PMID: 15520012); GO_0070814 (EC: ISS); GO_0071456 (EC: IEA); GO_0072341 (EC: IDA) PMID: 404147; 681363; 840498; 1301198; 2894761; 7506602; 7564249; 7598711; 7611293; 7635485; 7762555; 7849717; 7903580; 7929220; 7967489; 7981678; 8022826; 8353501; 8528202; 8755636; 8803779; 8990018; 9156316; 9266356; 9361025; 9383285; 9466992; 9590298; 9790750; 9889017; 10215408; 10338090; 10408774; 10434301; 10462600; 10791559; 10830953; 11013450; 11074524; 11149614; 11173483; 11204591; 11292330; 11310576; 11341749; 11359213; 11359462; 11434706; 11457468; 11483494; 11528503; 11575217; 11672761; 11748855; 11758232; 11872884; 12007221; 12015064; 12020105; 12082592; 12124992; 12154064; 12173932; 12180146; 12186157; 12228232; 12269827; 12379655; 12393509; 12413583; 12427542; 12439143; 12477932; 12529702; 12642343; 12649066; 12725044; 12815602; 12855221; 12889841; 14670973; 14977639; 15009965; 15082224; 15228193; 15354395; 15365998; 15489334; 15503105; 15520012; 15544339; 15554031; 15719048; 15748616; 15755387; 15772012; 15889417; 15922487; 15972722; 15975077; 16007597; 16013960; 16115349; 16189514; 16196087; 16205833; 16259797; 16274669; 16328059; 16363792; 16375773; 16422253; 16470595; 16479318; 16505479; 16541333; 16601865; 16709328; 16780588; 16791140; 16792904; 16941496; 16953589; 17035141; 17087506; 17119116; 17160942; 17311259; 17311260; 17319270; 17327360; 17352495; 17436311; 17540596; 17548676; 17553479; 17601350; 17621169; 17686644; 17726616; 17891500; 17956124; 17993766; 18029348; 18060852; 18203168; 18278872; 18398434; 18427977; 18447718; 18454451; 18614746; 18620331; 18622257; 18635682; 18636124; 18676680; 18708589; 18776696; 18781797; 18785313; 18792976; 18799873; 18818748; 18830263; 18839533; 18936436; 18950795; 18977241; 18977990; 18988749; 18992148; 19010420; 19019082; 19019335; 19019492; 19048631; 19064578; 19074437; 19112534; 19161160; 19166826; 19170196; 19238444; 19267073; 19370759; 19424622; 19429038; 19447967; 19493349; 19527514; 19531479; 19559392; 19593657; 19625176; 19657138; 19657388; 19683694; 19692168; 19722721; 19729796; 19737740; 19906435; 19913121; 19948975; 20031554; 20031578; 20056620; 20066033; 20082058; 20140262; 20160465; 20217437; 20237949; 20301697; 20308073; 20346360; 20379614; 20453000; 20458436; 20490928; 20506325; 20544798; 20559280; 20565774; 20601281; 20615890; 20628086; 20634891; 20638879; 20670920; 20707729; 20717043; 20718043; 20737570; 20883119; 20890573; 20939734; 20948192; 21045269; 21055808; 21062078; 21104445; 21139048; 21273695; 21319273; 21417705; 21517828; 21520339; 21564312; 21626167; 21886822; 21890473; 21900206; 21917271; 21957013; 21988832; 22002135; 22069143; 22118674; 22236648; 22253703; 22310774; 22333527; 22353391; 22470444; 22484094; 22512572; 22612060; 22665368; 22738154; 22863883; 22891245; 22977242; 22985361; 23002992; 23117410; 23124209; 23143240; 23152928; 23251661; 23430030; 23718855; 23720494; 23790103; 23824729; 23836652; 23954866; 23981774; 24316487 cystathionine-beta-synthase Ensembl:ENSG00000160200 HGNC:1550 HPRD:01994 MIM:613381 Vega:OTTHUMG00000086834 CBS Bin Zhao, Yue Liu, Oliver He CCN1 CCNA WEB: http://www.ncbi.nlm.nih.gov/gene CCNA2 cyclin A2 890 4q27 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0000079 (EC: IEA); GO_0000086 (EC: TAS); GO_0000278 (EC: TAS); GO_0001939 (EC: IEA); GO_0001940 (EC: IEA); GO_0005515 (EC: IPI); GO_0005634 (EC: IDA, PMID: 16109376); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA); GO_0007067 (EC: IEA); GO_0007095 (EC: TAS, PMID: 1312467); GO_0007265 (EC: IEP, PMID: 9054499); GO_0010389 (EC: IEA); GO_0019901 (EC: IEA); GO_0031100 (EC: IEA); GO_0032355 (EC: IEA); GO_0033762 (EC: IEA); GO_0045893 (EC: IEA); GO_0048146 (EC: IEA) PMID: 1312467; 1387877; 1532458; 1675006; 1830372; 1962755; 1967822; 7553852; 7630397; 7969176; 8024548; 8202514; 8230483; 8253383; 8423786; 8463339; 8475101; 8502485; 8626527; 8626584; 8647086; 8662825; 8684460; 8756328; 8756624; 8798463; 9020058; 9053846; 9054499; 9190208; 9199321; 9244350; 9311993; 9380407; 9566895; 9632134; 9660939; 9660973; 9716181; 9724724; 9820826; 9858587; 9885575; 9889196; 10339564; 10373534; 10486249; 10525536; 10540350; 10559858; 10581175; 10673397; 10679238; 10766737; 10864927; 10871850; 10884347; 10924145; 11113184; 11237594; 11238922; 11259605; 11310559; 11377199; 11598016; 11698641; 11884610; 11896577; 11907280; 11931757; 11940657; 11980909; 11983168; 12006580; 12044161; 12244298; 12439743; 12444551; 12477932; 12501191; 12601350; 12673206; 12676926; 12742823; 12853968; 12857729; 12941338; 12947099; 14579410; 14645522; 14646596; 14656438; 14695896; 14747563; 14749377; 14985333; 14993212; 15050687; 15187102; 15189033; 15199159; 15239650; 15306814; 15355997; 15455144; 15469821; 15489334; 15557281; 15558010; 15601848; 15647383; 15649124; 15649889; 15652749; 15671017; 15674323; 15782160; 15800615; 15800651; 15815621; 15828833; 15890360; 16009130; 16109376; 16123593; 16290148; 16327805; 16344560; 16398674; 16407256; 16540140; 16575904; 16670718; 16708383; 16774918; 16823179; 17001081; 17013808; 17043677; 17208191; 17254966; 17255290; 17316413; 17359356; 17361108; 17445807; 17495531; 17593077; 17636382; 17679094; 17698606; 17868400; 17917837; 18184650; 18246796; 18368381; 18391017; 18471975; 18485873; 18490441; 18572908; 18604603; 18635963; 18667424; 18668132; 18676680; 18829481; 19056339; 19098431; 19170196; 19176011; 19363140; 19483727; 19596857; 19614764; 19615732; 19625176; 19631451; 19671680; 19684852; 19692168; 19703905; 19738611; 19773423; 19822658; 19826003; 19858290; 19864233; 19901524; 20126974; 20133761; 20160477; 20193482; 20360068; 20453000; 20660152; 20733051; 20800603; 20857402; 21046779; 21078875; 21139048; 21145461; 21148318; 21241890; 21264543; 21308745; 21336306; 21447625; 21464733; 21472690; 21596315; 21762277; 21813648; 21858804; 21871181; 21903422; 21906983; 21952639; 21963094; 22158041; 22232705; 22465120; 22711989; 22718829; 22745723; 23028682; 23065011; 23115005; 23160376; 23455922; 23460259; 23602568; 23760262; 24013174; 24101496 cyclin A2 Ensembl:ENSG00000145386 HGNC:1578 HPRD:00453 MIM:123835 Vega:OTTHUMG00000133072 CCNA2 Bin Zhao, Yue Liu, Oliver He CCNB WEB: http://www.ncbi.nlm.nih.gov/gene CCNB1 cyclin B1 891 5q12 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0000079 (EC: IEA); GO_0000082 (EC: TAS); GO_0000086 (EC: TAS); GO_0000278 (EC: TAS); GO_0000922 (EC: IDA, PMID: 18195732); GO_0000942 (EC: IDA, PMID: 18195732); GO_0001556 (EC: IEA); GO_0001701 (EC: IEA); GO_0001933 (EC: IEA); GO_0005113 (EC: IPI, PMID: 11331587); GO_0005515 (EC: IPI, PMID: 10373560); GO_0005634 (EC: IDA, PMID: 11331587); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA); GO_0005813 (EC: IDA, PMID: 12524548); GO_0005829 (EC: TAS); GO_0006461 (EC: IEA); GO_0006468 (EC: IEA); GO_0007077 (EC: TAS); GO_0007080 (EC: IMP, PMID: 18195732); GO_0007283 (EC: IEA); GO_0009612 (EC: IEA); GO_0010629 (EC: IEA); GO_0016020 (EC: IEA); GO_0016301 (EC: IEA); GO_0019901 (EC: IPI, PMID: 12524548); GO_0031145 (EC: TAS); GO_0031442 (EC: IEA); GO_0033129 (EC: IEA); GO_0042246 (EC: IEA); GO_0042493 (EC: IEA); GO_0043148 (EC: IMP, PMID: 18195732); GO_0045931 (EC: IMP, PMID: 18195732); GO_0046680 (EC: IEA); GO_0048565 (EC: IEA); GO_0051437 (EC: TAS); GO_0051439 (EC: TAS); GO_0051726 (EC: TAS); GO_0051987 (EC: IMP, PMID: 18195732); GO_0055015 (EC: IEA); GO_0060045 (EC: IEA); GO_0060623 (EC: IEA); GO_0071174 (EC: IMP, PMID: 18195732); GO_0071283 (EC: IEA); GO_0071398 (EC: IEA); GO_0071407 (EC: IEA); GO_0071456 (EC: IEA) PMID: 1384126; 1386342; 1387877; 1717476; 1828290; 1836978; 2570636; 7474080; 7474100; 7494303; 7666531; 7737117; 7769006; 7799941; 7843284; 7876309; 7903056; 8070405; 8101826; 8397206; 8397207; 8402895; 8463339; 8475101; 8524869; 8662825; 8756624; 8889548; 9001210; 9053846; 9094673; 9244350; 9247342; 9315635; 9499405; 9515786; 9520381; 9560267; 9679058; 9813064; 9885575; 9891079; 9926943; 10339564; 10362260; 10373560; 10395539; 10421840; 10581175; 10716937; 10793135; 10799291; 10864927; 10958988; 10973963; 10995390; 11113184; 11238118; 11242082; 11259605; 11260656; 11278247; 11285280; 11310559; 11331587; 11444800; 11531413; 11559705; 11562349; 11572993; 11598127; 11642719; 11691994; 11732576; 11751633; 11779217; 11809526; 11836499; 11878934; 11960377; 12009577; 12054478; 12068134; 12097298; 12115375; 12124778; 12200597; 12379461; 12397081; 12424202; 12447691; 12468530; 12477932; 12483522; 12515609; 12524548; 12586340; 12612082; 12676926; 12684677; 12738867; 12775724; 12791267; 12839990; 12865421; 14645578; 14701726; 14760118; 14993212; 15016823; 15024056; 15181148; 15215233; 15256223; 15265780; 15489334; 15541388; 15623561; 15635413; 15654331; 15710382; 15749827; 15767402; 15790566; 15916961; 15931389; 15989971; 16009132; 16082198; 16109376; 16142332; 16159883; 16221667; 16226712; 16237118; 16273239; 16275333; 16322753; 16407259; 16474839; 16478538; 16479161; 16557593; 16614707; 16751065; 16784539; 16799550; 16880739; 16921029; 17098733; 17167975; 17242184; 17242210; 17274640; 17327911; 17359284; 17359356; 17360335; 17373649; 17386261; 17388661; 17389604; 17408621; 17431037; 17445807; 17466630; 17472438; 17495531; 17495533; 17513602; 17533373; 17586317; 17598982; 17655707; 17668170; 17679094; 17850284; 17881737; 18048386; 18059335; 18195732; 18281511; 18337751; 18353325; 18372919; 18408012; 18414058; 18445273; 18471975; 18491248; 18591933; 18593994; 18652313; 18671143; 18692784; 18799590; 18820706; 19028417; 19134343; 19162005; 19275580; 19275586; 19293801; 19344781; 19369249; 19458171; 19470724; 19475398; 19505905; 19608149; 19609944; 19614764; 19666607; 19724852; 19738611; 19763267; 19786724; 19820702; 19825974; 19826003; 19855194; 19968870; 20080579; 20095356; 20097574; 20103625; 20126263; 20160477; 20169205; 20171170; 20228808; 20334896; 20360007; 20360068; 20367638; 20368335; 20383333; 20404109; 20412769; 20453000; 20508983; 20526282; 20660152; 20661218; 20733051; 20733055; 20808790; 20810654; 20890132; 20927403; 20937773; 20956543; 20965177; 20974803; 21120602; 21139048; 21145461; 21148318; 21174181; 21241890; 21264543; 21276999; 21336306; 21379580; 21488187; 21489275; 21504622; 21525341; 21569376; 21596315; 21871181; 21890473; 21900495; 21900748; 21906983; 21925791; 21952639; 21963094; 21965721; 22014574; 22024040; 22024133; 22071694; 22137483; 22157815; 22158041; 22163316; 22193957; 22253775; 22266860; 22286100; 22391203; 22482362; 22508987; 22529100; 22532137; 22552851; 22580043; 22682366; 22726437; 22905155; 22939629; 22949227; 22965228; 23007861; 23091007; 23114644; 23239745; 23253261; 23383273; 23455922; 23460259; 23505570; 23602568; 23708605; 23775624; 23791783; 23874748; 23979597; 24145166; 24163370; 24248602; 24250222 cyclin B1 Ensembl:ENSG00000134057 HGNC:1579 HPRD:00454 MIM:123836 Vega:OTTHUMG00000097817 CCNB1 Bin Zhao, Yue Liu, Oliver He CCNE WEB: http://www.ncbi.nlm.nih.gov/gene CCNE1 cyclin E1 898 19q12 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000079 (EC: IEA); GO_0000082 (EC: NAS, PMID: 8207080); GO_0000082 (EC: TAS); GO_0000083 (EC: TAS); GO_0000278 (EC: TAS); GO_0000307 (EC: IEA); GO_0003713 (EC: NAS, PMID: 15572661); GO_0005515 (EC: IPI, PMID: 10330164); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005829 (EC: TAS); GO_0006270 (EC: IEA); GO_0006468 (EC: IMP, PMID: 10500095); GO_0016055 (EC: IEA); GO_0016301 (EC: IEA); GO_0016538 (EC: IEA); GO_0019901 (EC: IEA); GO_0030521 (EC: NAS, PMID: 15572661); GO_0045893 (EC: NAS, PMID: 15572661); GO_0050681 (EC: NAS, PMID: 15572661); GO_0051301 (EC: IEA) PMID: 1388095; 1388288; 1833066; 1833068; 7629134; 7698009; 7739542; 7799941; 8207080; 8230483; 8253383; 8617791; 8618861; 8647086; 8649818; 8662825; 8756624; 8769642; 8833152; 8861947; 8867812; 8891332; 8978686; 9012818; 9053846; 9139732; 9153308; 9190208; 9192873; 9192874; 9218599; 9223324; 9311993; 9380407; 9453249; 9472014; 9525916; 9545286; 9632134; 9660939; 9716181; 9731206; 9819444; 9840927; 9840943; 9885575; 9886493; 9891079; 10202152; 10330164; 10339564; 10359664; 10393546; 10454565; 10486249; 10499591; 10499802; 10500095; 10581175; 10593981; 10751146; 10790373; 10827081; 10851086; 10908655; 10953010; 10995386; 10995387; 11085541; 11132966; 11175348; 11221854; 11237742; 11259605; 11477082; 11533444; 11565033; 11565034; 11733001; 11838966; 11877298; 11884622; 11907280; 11919196; 11940657; 12096339; 12096344; 12101670; 12114499; 12133429; 12444551; 12477932; 12529437; 12533700; 12553912; 12601350; 12607005; 12628165; 12647795; 12676926; 12729791; 12777997; 12778072; 12800980; 12824885; 12839982; 12857729; 13678583; 14536078; 14612403; 14645251; 14701826; 14719078; 14739463; 14965268; 14985333; 14999283; 15004009; 15004027; 15007381; 15024056; 15060836; 15178429; 15191351; 15197178; 15343382; 15364936; 15467469; 15469821; 15489334; 15514162; 15555599; 15557281; 15557791; 15572661; 15611651; 15660127; 15665273; 15670215; 15708847; 15709169; 15800651; 15800668; 15980150; 15980415; 16109376; 16124066; 16191374; 16223725; 16289656; 16322693; 16338364; 16344560; 16391523; 16504183; 16538501; 16582606; 16609025; 16627785; 16740753; 16761619; 16765349; 16799991; 16818231; 16823179; 16912169; 17192413; 17218276; 17254966; 17254967; 17293600; 17298674; 17325036; 17360482; 17361108; 17409409; 17431037; 17434132; 17525332; 17646408; 17661632; 17664332; 17726548; 17822621; 17970072; 18029348; 18047954; 18174243; 18208561; 18276582; 18281541; 18301453; 18344087; 18381935; 18455747; 18507837; 18508766; 18559665; 18607847; 18651214; 18799628; 18799789; 18851830; 18959818; 18977205; 19010853; 19058005; 19064572; 19084516; 19107593; 19111882; 19124506; 19179977; 19236751; 19258477; 19305161; 19318554; 19321444; 19423708; 19454496; 19470470; 19470724; 19505905; 19561641; 19569046; 19574535; 19585504; 19587092; 19603101; 19615252; 19617534; 19621596; 19631451; 19670700; 19713765; 19724860; 19738611; 19787784; 19801544; 19860623; 19925052; 20001501; 20102401; 20107311; 20171175; 20336784; 20385564; 20453000; 20453888; 20465575; 20508983; 20530684; 20530685; 20587660; 20607601; 20837141; 20837705; 20972438; 21048031; 21092281; 21103391; 21148318; 21150326; 21179471; 21241890; 21315112; 21372285; 21458381; 21464733; 21472690; 21515670; 21597324; 21620836; 21746877; 21750416; 21792910; 21918011; 21941773; 21952639; 21965652; 21988832; 22120721; 22158041; 22285861; 22388891; 22441703; 22449977; 22460364; 22484283; 22558078; 22763761; 22763964; 22945645; 22958293; 22959436; 23044415; 23109421; 23185313; 23324395; 23378270; 23383003; 23416081; 23453757; 23455922; 23543735; 23602568; 23625206; 23775012; 23787073; 23900874; 23910095; 23955388; 24026986; 24129577; 24145166; 24218601; 24250222; 24298052; 24370822 cyclin E1 Ensembl:ENSG00000105173 HGNC:1589 HPRD:00455 MIM:123837 Vega:OTTHUMG00000177626 CCNE1 Bin Zhao, Yue Liu, Oliver He CD3-DELTA IMD19 T3D WEB: http://www.ncbi.nlm.nih.gov/gene CD3D CD3d molecule, delta (CD3-TCR complex) 915 11q23 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0003713 (EC: IDA, PMID: 2017177); GO_0004888 (EC: IC, PMID: 9485181); GO_0005737 (EC: NAS, PMID: 1831653); GO_0005886 (EC: TAS); GO_0007166 (EC: IC, PMID: 9485181); GO_0016021 (EC: IEA); GO_0030217 (EC: IDA, PMID: 2017177); GO_0031295 (EC: TAS); GO_0042101 (EC: IDA, PMID: 8176201); GO_0042101 (EC: NAS, PMID: 9485181); GO_0042105 (EC: IEA); GO_0045059 (EC: ISS); GO_0045944 (EC: IDA, PMID: 2017177); GO_0046982 (EC: IPI, PMID: 9485181); GO_0050776 (EC: TAS); GO_0050852 (EC: TAS) PMID: 1372642; 1385321; 1826255; 1831653; 1832084; 1979339; 2017177; 2111780; 2138083; 2540970; 2826124; 2859526; 2939461; 3478717; 3488209; 6095101; 7495730; 7506554; 7517794; 7539755; 7719941; 7774645; 8020575; 8125527; 8145026; 8176201; 8278814; 8621641; 8809126; 9045614; 9263011; 9485181; 9510190; 9582308; 9743208; 10722370; 11048639; 11827988; 12215456; 12410792; 12477932; 12522270; 12604782; 14602880; 15028279; 15144186; 15331598; 15489334; 15489916; 15534202; 15546002; 15592455; 15778375; 16094384; 16407162; 16412509; 16777597; 16822850; 16888097; 17001685; 17023417; 17176095; 17502376; 17632570; 17652306; 17872946; 17923503; 17928336; 18473783; 18541215; 18803280; 18808677; 19056690; 19222422; 19724882; 19726522; 19759518; 19942855; 20012528; 20179761; 20237496; 20478055; 20511557; 20594957; 20660709; 20824090; 21669053; 21669059; 21670311; 21926461; 21984702; 22103833; 22401598; 22505724; 22911005; 23336327 CD3d molecule, delta (CD3-TCR complex) Ensembl:ENSG00000167286 HGNC:1673 HPRD:01730 MIM:186790 Vega:OTTHUMG00000166970 CD3D Bin Zhao, Yue Liu, Oliver He IMD18 T3E TCRE WEB: http://www.ncbi.nlm.nih.gov/gene CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 11q23 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0001772 (EC: IEA); GO_0002669 (EC: IEA); GO_0004888 (EC: NAS, PMID: 9485181); GO_0005057 (EC: TAS, PMID: 1370449); GO_0005515 (EC: IPI, PMID: 11855827); GO_0005886 (EC: IDA, PMID: 11390434); GO_0005886 (EC: TAS); GO_0005887 (EC: NAS, PMID: 9485181); GO_0006461 (EC: NAS, PMID: 9886373); GO_0007166 (EC: NAS, PMID: 12110186); GO_0007169 (EC: TAS, PMID: 8530500); GO_0007172 (EC: TAS, PMID: 8490660); GO_0007186 (EC: TAS, PMID: 8530500); GO_0007584 (EC: IEA); GO_0009897 (EC: IDA, PMID: 11390434); GO_0017124 (EC: IPI, PMID: 12110186); GO_0019901 (EC: NAS, PMID: 12110186); GO_0030159 (EC: NAS, PMID: 9886373); GO_0031295 (EC: TAS); GO_0032729 (EC: IEA); GO_0032753 (EC: IEA); GO_0035556 (EC: TAS, PMID: 1370449); GO_0042101 (EC: IDA, PMID: 8176201); GO_0042101 (EC: NAS, PMID: 9485181); GO_0042102 (EC: IMP, PMID: 12110186); GO_0042105 (EC: IEA); GO_0042110 (EC: NAS, PMID: 12110186); GO_0042608 (EC: NAS, PMID: 11186279); GO_0042981 (EC: NAS, PMID: 12567487); GO_0045060 (EC: IEA); GO_0045086 (EC: IEA); GO_0045879 (EC: IEA); GO_0046641 (EC: IEA); GO_0046982 (EC: IPI, PMID: 9485181); GO_0050731 (EC: IEA); GO_0050776 (EC: TAS); GO_0050850 (EC: IEA); GO_0050852 (EC: TAS); GO_0097190 (EC: IEA) PMID: 1370449; 1385321; 1387664; 1671006; 1832084; 1979339; 2111780; 2138083; 2859526; 3012357; 3267235; 3478717; 7499176; 7500045; 7506554; 7514106; 7517794; 7539755; 7541024; 7699329; 7761456; 7774645; 8125527; 8145026; 8176201; 8366117; 8490660; 8530500; 8621646; 8626450; 8809126; 8906806; 8920877; 9045614; 9120393; 9263011; 9312149; 9378960; 9485181; 9510190; 9582308; 9687533; 9698567; 9743208; 9780176; 9886373; 10373416; 10722370; 11048639; 11115514; 11186279; 11349123; 11390434; 11439187; 11689561; 11827988; 11855827; 12110186; 12410792; 12477932; 12499387; 12522270; 12567487; 12626537; 12734335; 12812314; 14523017; 14757743; 15123239; 15144186; 15342556; 15489334; 15489916; 15534202; 15546002; 15592455; 16094384; 16308105; 16412509; 16461343; 16777597; 17001685; 17023417; 17176095; 17213291; 17507663; 17630354; 17632570; 17652306; 17668204; 17928336; 18473783; 18504423; 18541215; 18555270; 18555888; 18667496; 18808677; 19190244; 19616027; 19724882; 19726522; 19759518; 19913121; 20012528; 20179761; 20237496; 20478055; 20594957; 20628086; 20824090; 21203507; 21669053; 21669059; 21980389; 22401598; 22505724; 22911005; 23166358; 23216707 CD3e molecule, epsilon (CD3-TCR complex) Ensembl:ENSG00000198851 HGNC:1674 HPRD:08923 MIM:186830 Vega:OTTHUMG00000166968 CD3E Bin Zhao, Yue Liu, Oliver He CD3-GAMMA IMD17 T3G WEB: http://www.ncbi.nlm.nih.gov/gene CD3G CD3g molecule, gamma (CD3-TCR complex) 917 11q23 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0004888 (EC: IMP, PMID: 12794121); GO_0005886 (EC: TAS); GO_0005887 (EC: NAS, PMID: 9485181); GO_0006461 (EC: NAS, PMID: 12794121); GO_0007163 (EC: IMP, PMID: 12407027); GO_0007166 (EC: IMP, PMID: 12407027); GO_0015031 (EC: IMP, PMID: 12794121); GO_0030159 (EC: NAS, PMID: 12794121); GO_0031295 (EC: TAS); GO_0038096 (EC: TAS); GO_0042101 (EC: NAS, PMID: 9485181); GO_0042105 (EC: IEA); GO_0042110 (EC: NAS, PMID: 12407027); GO_0042608 (EC: NAS, PMID: 11186279); GO_0045087 (EC: TAS); GO_0046982 (EC: IPI, PMID: 9485181); GO_0050776 (EC: TAS); GO_0050852 (EC: TAS); GO_0070228 (EC: IMP, PMID: 12407027) PMID: 1385321; 1387664; 1535555; 1635567; 1709425; 1826255; 1832084; 1979339; 2111780; 2138083; 2139676; 2540970; 2547833; 2826124; 2944745; 3112151; 3478717; 7506554; 7517794; 7533164; 7539755; 7774645; 8125298; 8125527; 8145026; 8636209; 8809126; 9045614; 9263011; 9485181; 9510190; 9582308; 9743208; 10722370; 11048639; 11186279; 11298321; 11827988; 12374807; 12407027; 12410792; 12477932; 12794121; 15459203; 15489334; 15489916; 15638726; 15778375; 15879122; 16094384; 16344560; 16777597; 16888097; 16888650; 16916653; 17001685; 17023417; 17176095; 17632570; 17652306; 17822534; 17923503; 17928336; 18051367; 18473783; 18541215; 18808677; 18815285; 19056690; 19536290; 19724882; 19726522; 19759518; 19860678; 19898481; 20012528; 20179761; 20237496; 20478055; 20511557; 20594957; 20660709; 20824090; 21669053; 21669059; 21670311; 21764047; 21984702; 22401598; 22482414; 22505724; 22731821; 22911005; 23336327; 23348211; 23590417 CD3g molecule, gamma (CD3-TCR complex) HGNC:1675 HPRD:07037 MIM:186740 CD3G Bin Zhao, Yue Liu, Oliver He CD3-ZETA CD3H CD3Q CD3Z T3Z TCRZ WEB: http://www.ncbi.nlm.nih.gov/gene CD247 CD247 molecule 919 RP11-104L21.1 1q24.2 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0004888 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10704231); GO_0005737 (EC: IDA, PMID: 11390434); GO_0005886 (EC: IDA, PMID: 11390434); GO_0005886 (EC: TAS); GO_0016021 (EC: IEA); GO_0016032 (EC: TAS); GO_0031295 (EC: TAS); GO_0038096 (EC: TAS); GO_0042101 (EC: IDA, PMID: 8176201); GO_0042105 (EC: IEA); GO_0042802 (EC: IPI, PMID: 17055436); GO_0042803 (EC: NAS, PMID: 12110186); GO_0045087 (EC: TAS); GO_0050690 (EC: TAS); GO_0050776 (EC: TAS); GO_0050852 (EC: TAS) PMID: 1385158; 1385321; 1390434; 1454062; 1530920; 1532817; 1717577; 2111780; 2138083; 2138330; 2145165; 2845582; 2974162; 3478717; 3785426; 7514106; 7517794; 7526385; 7528772; 7589084; 7629168; 7680960; 7737297; 7842742; 8125298; 8176201; 8366117; 8409430; 8417118; 8621646; 8626561; 8656061; 8675217; 8760790; 8809126; 8906806; 8977276; 9036949; 9045614; 9047237; 9172452; 9368621; 9448136; 9484780; 9485181; 9510190; 9575182; 9625766; 9677202; 9687533; 9743208; 9880255; 10224289; 10424441; 10449770; 10704231; 10722370; 10799879; 11048639; 11349123; 11353765; 11390434; 11463741; 11525746; 11572860; 11714771; 11827988; 11851345; 11891219; 11916964; 11920499; 11950832; 12100036; 12110186; 12165490; 12176041; 12202152; 12356870; 12420108; 12421992; 12477932; 12522270; 12587826; 12731048; 12734410; 12755691; 12847689; 12902492; 12928398; 14523017; 14526327; 14550268; 14672952; 14715568; 14757743; 14967045; 15084271; 15144186; 15186530; 15274412; 15323357; 15489334; 15489916; 15592455; 15641485; 15659558; 15743765; 15749888; 15879101; 15922712; 16049493; 16094384; 16337488; 16393980; 16454711; 16461343; 16616055; 16672702; 16710414; 17001685; 17054067; 17055436; 17134238; 17134755; 17176095; 17255353; 17464179; 17652306; 17951997; 17997796; 18051367; 18174230; 18178846; 18207249; 18215426; 18438604; 18463433; 18505733; 18714041; 18721908; 18787188; 19064610; 19082633; 19090773; 19201859; 19229850; 19259799; 19422667; 19536175; 19664385; 19710135; 19898481; 20032419; 20118245; 20179761; 20190752; 20237496; 20383147; 20453842; 20637659; 20723304; 21383967; 21474487; 21669053; 21669059; 21750679; 21779181; 21988832; 22004975; 22221142; 22292024; 22294642; 22345473; 22401598; 22505724; 22536368; 22551306; 22798681; 22844345; 22911005; 23057733; 23228155; 23525753; 23861880; 23916875 CD247 molecule Ensembl:ENSG00000198821 HGNC:1677 HPRD:01729 MIM:186780 Vega:OTTHUMG00000034593 CD247 Bin Zhao, Yue Liu, Oliver He CD4mut WEB: http://www.ncbi.nlm.nih.gov/gene CD4 CD4 molecule 920 12p13.31 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0001816 (EC: IEA); GO_0001948 (EC: IPI, PMID: 10922058); GO_0004872 (EC: TAS, PMID: 10413516); GO_0004888 (EC: TAS, PMID: 10358157); GO_0005201 (EC: NAS, PMID: 12444132); GO_0005515 (EC: IPI, PMID: 11113139); GO_0005769 (EC: TAS); GO_0005788 (EC: IEA); GO_0005789 (EC: TAS); GO_0005886 (EC: IDA, PMID: 11390434); GO_0005886 (EC: TAS); GO_0006948 (EC: IDA, PMID: 9166430); GO_0006955 (EC: NAS, PMID: 8512039); GO_0007155 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10358157); GO_0007166 (EC: TAS, PMID: 9780207); GO_0007167 (EC: TAS, PMID: 10358157); GO_0007169 (EC: NAS, PMID: 8512039); GO_0008270 (EC: IDA, PMID: 9668045); GO_0009897 (EC: IDA, PMID: 17213291); GO_0015026 (EC: NAS, PMID: 8512039); GO_0016021 (EC: IEA); GO_0016032 (EC: TAS); GO_0019899 (EC: IPI, PMID: 19333378); GO_0019901 (EC: IPI, PMID: 7486703); GO_0030217 (EC: IDA, PMID: 1533274); GO_0030260 (EC: TAS); GO_0031295 (EC: TAS); GO_0032507 (EC: IDA, PMID: 15128768); GO_0042101 (EC: NAS, PMID: 8512039); GO_0042289 (EC: NAS, PMID: 8512039); GO_0042803 (EC: IDA, PMID: 12444132); GO_0045058 (EC: IDA, PMID: 9551897); GO_0045086 (EC: NAS, PMID: 1901411); GO_0045087 (EC: TAS); GO_0045121 (EC: IEA); GO_0045234 (EC: IDA, PMID: 15128768); GO_0045860 (EC: IDA, PMID: 2118992); GO_0050690 (EC: TAS); GO_0050731 (EC: IEA); GO_0050829 (EC: IEA); GO_0050850 (EC: IEA); GO_0050852 (EC: TAS); GO_0050863 (EC: IDA, PMID: 1533274) PMID: 153; 200; 237459; 1279195; 1280382; 1281202; 1310988; 1348943; 1352879; 1354681; 1354808; 1356673; 1370558; 1370739; 1373203; 1373549; 1374095; 1376134; 1376135; 1378510; 1380099; 1380260; 1381201; 1381203; 1381399; 1382339; 1388715; 1402655; 1425921; 1433512; 1438278; 1457205; 1457207; 1465431; 1472279; 1489581; 1491632; 1493050; 1500858; 1501286; 1501294; 1503822; 1512692; 1520872; 1527858; 1533274; 1535086; 1535787; 1537337; 1543562; 1546447; 1548744; 1548763; 1548769; 1549584; 1551875; 1563094; 1565858; 1567578; 1569213; 1588493; 1592430; 1599754; 1602552; 1605591; 1614536; 1618861; 1622897; 1627247; 1636088; 1639820; 1674549; 1677023; 1678778; 1685857; 1687500; 1690236; 1690832; 1691226; 1691563; 1693676; 1696539; 1697332; 1698804; 1698911; 1698964; 1701030; 1701782; 1702163; 1702842; 1703212; 1706342; 1708753; 1709701; 1710248; 1711033; 1711118; 1713252; 1713692; 1717587; 1717717; 1720590; 1720627; 1720631; 1721822; 1722676; 1724568; 1727475; 1727486; 1727487; 1727497; 1730924; 1732513; 1736938; 1738091; 1742075; 1757107; 1763044; 1810199; 1832782; 1834739; 1845049; 1851800; 1870202; 1870209; 1871120; 1888898; 1889086; 1896455; 1899141; 1901411; 1910691; 1918997; 1931229; 1931230; 1959561; 1967269; 1967280; 1970124; 1970444; 1971526; 1977427; 1978941; 1979339; 1979910; 1983967; 1984054; 1985197; 1985202; 1991970; 1995942; 2006155; 2007979; 2014052; 2015114; 2018763; 2040625; 2040664; 2045792; 2059359; 2062847; 2068099; 2076345; 2078013; 2078408; 2078409; 2082620; 2103853; 2104682; 2107024; 2109100; 2111957; 2115689; 2118992; 2125484; 2136376; 2171457; 2182910; 2187500; 2190096; 2190604; 2190605; 2198840; 2212945; 2214026; 2243375; 2247146; 2251501; 2261984; 2324685; 2325207; 2335819; 2339113; 2341717; 2363051; 2364018; 2374593; 2402498; 2431105; 2431482; 2432599; 2436231; 2437327; 2438696; 2441727; 2441877; 2446880; 2453925; 2461565; 2462895; 2468713; 2475780; 2479005; 2482055; 2523711; 2536098; 2537355; 2538505; 2538547; 2541915; 2543930; 2545918; 2549633; 2549987; 2550671; 2550679; 2555159; 2558637; 2558687; 2559777; 2571187; 2592374; 2821115; 2829022; 2829023; 2830667; 2833917; 2842778; 2845147; 2846691; 2851650; 2986290; 2986291; 2990682; 2990730; 2995487; 3001934; 3006256; 3016552; 3018753; 3023102; 3027168; 3029227; 3038935; 3086883; 3095663; 3118220; 3257102; 3259291; 3260352; 3261864; 3263213; 3304356; 3466790; 3484980; 3495568; 3497054; 3652531; 3682024; 6096719; 7486703; 7494500; 7504739; 7506554; 7515973; 7521897; 7522245; 7529290; 7529735; 7533854; 7537501; 7539035; 7539755; 7541827; 7543586; 7544051; 7545243; 7545244; 7546903; 7562439; 7576913; 7576930; 7589091; 7589092; 7592573; 7594524; 7615007; 7616571; 7618285; 7636191; 7650480; 7676667; 7678271; 7685405; 7686944; 7687306; 7688299; 7688827; 7689324; 7690418; 7690724; 7692037; 7692087; 7693970; 7707502; 7734186; 7737288; 7754236; 7769669; 7769687; 7774645; 7778293; 7821926; 7831289; 7831801; 7832633; 7853478; 7853484; 7867080; 7871751; 7874384; 7897355; 7897356; 7902127; 7903106; 7903128; 7903479; 7904348; 7904351; 7904656; 7906314; 7906657; 7910967; 7913036; 7914230; 7917519; 7935503; 7961587; 7975260; 7982906; 7983750; 8035515; 8043225; 8057354; 8075984; 8091666; 8091684; 8102473; 8104794; 8105835; 8122371; 8124721; 8125527; 8129620; 8139010; 8139011; 8151300; 8151301; 8151774; 8160267; 8168144; 8178478; 8196669; 8212576; 8230446; 8246987; 8262036; 8280475; 8289353; 8331723; 8331733; 8350411; 8356059; 8361381; 8363802; 8369162; 8409933; 8411350; 8416385; 8417177; 8419649; 8419650; 8437224; 8437228; 8437234; 8438588; 8455141; 8460995; 8464887; 8474162; 8497074; 8497077; 8510207; 8510209; 8512039; 8516299; 8547064; 8551569; 8551601; 8551619; 8552983; 8560759; 8560767; 8568275; 8575195; 8599214; 8599229; 8599760; 8599832; 8605026; 8613144; 8615015; 8615021; 8615032; 8627160; 8627264; 8627711; 8629022; 8635586; 8648738; 8649438; 8659106; 8661396; 8661397; 8663408; 8674119; 8674120; 8707350; 8709227; 8723724; 8726523; 8738430; 8760413; 8801439; 8805353; 8806567; 8806575; 8811198; 8827217; 8827218; 8849450; 8862276; 8871625; 8882662; 8887470; 8887682; 8891109; 8892926; 8896248; 8898753; 8906795; 8906796; 8906988; 8924209; 8948487; 8973529; 8976200; 8977179; 8986758; 8995609; 9000083; 9002959; 9036944; 9037057; 9043947; 9049297; 9049413; 9052838; 9074930; 9123823; 9151836; 9166430; 9168119; 9168885; 9185604; 9186786; 9226175; 9261346; 9263011; 9264287; 9269777; 9334377; 9344703; 9349472; 9360974; 9377118; 9417096; 9420225; 9443108; 9445013; 9451022; 9473011; 9499087; 9499113; 9499115; 9525683; 9525894; 9546790; 9548463; 9551897; 9558100; 9573233; 9576954; 9600078; 9600268; 9601645; 9604776; 9614108; 9621091; 9622505; 9632396; 9632631; 9637477; 9641677; 9653051; 9658072; 9658081; 9660940; 9668045; 9696823; 9721247; 9724097; 9739096; 9770524; 9780207; 9811606; 9811611; 9826718; 9862697; 9870313; 9918507; 9923610; 9989602; 10074122; 10089882; 10199403; 10202115; 10208934; 10213312; 10213313; 10233996; 10329539; 10358157; 10364484; 10371171; 10375525; 10375528; 10393974; 10413516; 10430052; 10438529; 10446313; 10451539; 10482576; 10490978; 10505674; 10508188; 10557278; 10558884; 10559275; 10559349; 10562325; 10581250; 10582593; 10589997; 10590121; 10593874; 10600606; 10606089; 10623731; 10623764; 10644351; 10684310; 10738970; 10758170; 10774549; 10776787; 10779509; 10816381; 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15063762; 15078178; 15090827; 15099523; 15109676; 15113900; 15113923; 15113926; 15128768; 15161081; 15166428; 15166429; 15168796; 15180540; 15180541; 15183057; 15194762; 15194768; 15202998; 15215692; 15258189; 15279588; 15279589; 15308718; 15308751; 15317218; 15321703; 15326605; 15340161; 15371410; 15489307; 15489334; 15489916; 15494497; 15542675; 15572157; 15577644; 15585836; 15611114; 15613479; 15616015; 15638726; 15650196; 15660419; 15665647; 15665762; 15714205; 15719026; 15722538; 15729334; 15731180; 15737612; 15748209; 15748900; 15767435; 15767436; 15778371; 15784911; 15797855; 15807900; 15821887; 15823605; 15854903; 15857992; 15857997; 15890908; 15890935; 15893666; 15929700; 15936090; 15956589; 15956605; 15964018; 15972448; 15975620; 15977243; 15983047; 15990565; 15996703; 16002156; 16046522; 16047221; 16091223; 16103167; 16106369; 16116206; 16148047; 16174727; 16185162; 16188969; 16227248; 16282475; 16284180; 16300985; 16309726; 16310238; 16314494; 16315040; 16331979; 16344560; 16354571; 16365153; 16426633; 16439540; 16454711; 16476977; 16497223; 16507315; 16515489; 16611063; 16616288; 16631599; 16684552; 16702010; 16721558; 16736946; 16753228; 16758122; 16762062; 16775320; 16777164; 16796521; 16817962; 16821115; 16829607; 16855325; 16873261; 16886053; 16886061; 16888650; 16951326; 16955142; 16963439; 16979207; 16987062; 17001685; 17005819; 17010381; 17020785; 17030448; 17035237; 17042973; 17053352; 17065205; 17077296; 17082567; 17083721; 17084877; 17121788; 17121803; 17132727; 17144914; 17151103; 17157668; 17158233; 17170457; 17175221; 17180012; 17187670; 17213291; 17234232; 17235436; 17237241; 17239419; 17251298; 17251303; 17252589; 17267500; 17269928; 17292399; 17304105; 17320923; 17328229; 17329339; 17334223; 17344303; 17346169; 17346946; 17360741; 17363727; 17413690; 17462597; 17485285; 17507486; 17522341; 17526486; 17543960; 17586316; 17586321; 17591854; 17599917; 17628860; 17632197; 17632570; 17645467; 17652306; 17652391; 17653867; 17676933; 17686993; 17712998; 17721546; 17726154; 17728240; 17824250; 17825297; 17855336; 17885647; 17888880; 17904606; 17937819; 17947540; 17956985; 17959679; 17975141; 17980430; 18032634; 18035040; 18045872; 18061610; 18078954; 18089681; 18097956; 18156204; 18162176; 18167642; 18187620; 18197116; 18204854; 18205604; 18205925; 18237398; 18242797; 18261176; 18296630; 18310503; 18353949; 18376303; 18377648; 18390744; 18418773; 18432409; 18438604; 18451325; 18468560; 18473783; 18480458; 18500445; 18508887; 18523251; 18524826; 18541215; 18566427; 18579178; 18579609; 18590744; 18619974; 18624812; 18632854; 18668044; 18672082; 18672260; 18676680; 18691022; 18704932; 18713475; 18715908; 18725938; 18786994; 18789977; 18808677; 18833294; 18837996; 18924611; 18976462; 18976975; 18977142; 18987145; 18991615; 19000821; 19004052; 19018669; 19019953; 19020832; 19064722; 19066282; 19103208; 19129443; 19144136; 19146681; 19149577; 19170196; 19170639; 19180463; 19192224; 19196101; 19275586; 19289577; 19301975; 19324886; 19327048; 19333378; 19366992; 19403684; 19439470; 19449444; 19478876; 19492063; 19493998; 19505389; 19535453; 19553323; 19553524; 19556424; 19572057; 19573080; 19596013; 19625176; 19643141; 19664391; 19667946; 19667950; 19671162; 19692168; 19692474; 19692476; 19692480; 19715524; 19734912; 19751272; 19770068; 19773279; 19777054; 19781555; 19798410; 19812686; 19813706; 19843086; 19851458; 19895210; 19917496; 19926478; 19933330; 19944437; 19965434; 20007245; 20012522; 20012528; 20041213; 20051874; 20078884; 20080564; 20088758; 20132229; 20139419; 20162270; 20166763; 20179761; 20186035; 20195464; 20197275; 20201792; 20213609; 20224778; 20227370; 20237496; 20357769; 20380698; 20388015; 20403730; 20420669; 20442859; 20447038; 20448211; 20458450; 20463063; 20463068; 20463957; 20465832; 20494390; 20501362; 20504833; 20507591; 20530479; 20539016; 20558728; 20562332; 20568250; 20570309; 20594957; 20610714; 20622010; 20631314; 20638642; 20659345; 20724730; 20729906; 20730055; 20739067; 20819778; 20826747; 20835359; 20847001; 20858517; 20860805; 20874088; 20880565; 20881088; 20924289; 20930173; 20943653; 20961591; 20974815; 20974843; 20980513; 21041720; 21048031; 21057376; 21060818; 21068258; 21110955; 21134642; 21142701; 21146497; 21152581; 21165790; 21176220; 21177324; 21179414; 21179576; 21193846; 21209878; 21216423; 21249232; 21249500; 21255440; 21257970; 21284901; 21289125; 21310048; 21324454; 21325401; 21346189; 21351734; 21357438; 21357743; 21376048; 21382342; 21411542; 21430066; 21444771; 21465559; 21482738; 21487012; 21491089; 21543478; 21557772; 21593147; 21600899; 21601230; 21607084; 21612582; 21613393; 21625496; 21626027; 21637819; 21651772; 21660189; 21674066; 21697467; 21709158; 21709254; 21715496; 21738584; 21744325; 21750724; 21757642; 21760891; 21763239; 21769486; 21792088; 21800875; 21827143; 21845735; 21849975; 21851958; 21861776; 21875413; 21880749; 21886150; 21900604; 21902583; 21909273; 21917951; 21922073; 21931551; 21949691; 21957314; 21988832; 21994452; 21994772; 22006924; 22013062; 22017399; 22032685; 22069466; 22083481; 22090097; 22103831; 22103832; 22103833; 22103834; 22103836; 22103838; 22117536; 22158072; 22163292; 22163344; 22171785; 22175768; 22209232; 22222210; 22283893; 22284360; 22291690; 22291921; 22301137; 22301152; 22310634; 22329717; 22337266; 22345473; 22357275; 22378925; 22384114; 22404213; 22419808; 22433250; 22437554; 22446965; 22451932; 22466163; 22479399; 22479639; 22482414; 22497421; 22505724; 22524483; 22545156; 22547820; 22551420; 22553332; 22606344; 22624045; 22640559; 22640659; 22672991; 22674993; 22687513; 22696649; 22751485; 22773820; 22797698; 22808111; 22826297; 22844345; 22846998; 22863293; 22908191; 22933284; 22959895; 22980333; 23077246; 23098499; 23151229; 23158993; 23185351; 23225889; 23282736; 23340699; 23364796; 23426363; 23470050; 23691059; 23692566; 23700441; 23729440; 23807677; 23863698; 23923047; 24006463; 24257748 CD4 molecule Ensembl:ENSG00000010610 HGNC:1678 HPRD:01740 MIM:186940 Vega:OTTHUMG00000168514 CD4 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene CD14 CD14 molecule 929 5q31.1 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0001530 (EC: IDA, PMID: 12594207); GO_0001847 (EC: TAS, PMID: 2402637); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0005515 (EC: IPI); GO_0005576 (EC: TAS); GO_0005615 (EC: IEA); GO_0005886 (EC: TAS); GO_0006909 (EC: TAS, PMID: 9548256); GO_0006915 (EC: TAS, PMID: 9548256); GO_0006954 (EC: IEA); GO_0007166 (EC: TAS, PMID: 8798531); GO_0007249 (EC: TAS); GO_0009408 (EC: IEA); GO_0009986 (EC: IEA); GO_0010008 (EC: TAS); GO_0016019 (EC: TAS, PMID: 8798531); GO_0031225 (EC: IEA); GO_0032026 (EC: IEA); GO_0032760 (EC: IDA, PMID: 12594207); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034612 (EC: IEA); GO_0035666 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0045087 (EC: TAS); GO_0045121 (EC: IEA); GO_0045471 (EC: IEA); GO_0045807 (EC: IEA); GO_0050715 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070891 (EC: IDA, PMID: 12594207); GO_0071222 (EC: IDA, PMID: 12594207); GO_0071223 (EC: IDA, PMID: 12594207) PMID: 2402637; 2448876; 2453848; 2462937; 2472171; 2779588; 3385210; 7583357; 8798531; 9142045; 9548256; 9562334; 9655682; 9665271; 10395652; 10575214; 11062291; 11076863; 11083760; 11145656; 11199329; 11257272; 11282774; 11343243; 11489942; 11732288; 11745332; 11779220; 11810121; 11825494; 11841490; 11843056; 11854210; 11876746; 11932927; 11935032; 11985523; 12006789; 12011764; 12067299; 12075251; 12082592; 12101079; 12103253; 12106839; 12117913; 12126249; 12140663; 12171914; 12174084; 12185442; 12196527; 12207338; 12324469; 12404174; 12410798; 12414752; 12417309; 12438323; 12450609; 12477932; 12492251; 12566518; 12580907; 12594207; 12624278; 12663765; 12679473; 12700637; 12731067; 12754215; 12756848; 12757265; 12825176; 12832426; 12853157; 12885845; 12897754; 12911501; 12938192; 12940436; 12942028; 12960274; 14500479; 14508193; 14510720; 14517492; 14517520; 14587643; 14617510; 14624155; 14648231; 14672339; 14673018; 14706103; 14720421; 14739370; 14996480; 15034063; 15039096; 15069085; 15080833; 15081257; 15116260; 15120158; 15132789; 15143473; 15164100; 15166925; 15175649; 15190267; 15207785; 15257175; 15269840; 15273551; 15292769; 15342556; 15356557; 15358661; 15369724; 15373760; 15378299; 15489334; 15489336; 15491315; 15516360; 15520404; 15558232; 15591473; 15599151; 15602630; 15619435; 15640605; 15647432; 15655821; 15670766; 15686783; 15714129; 15741437; 15753758; 15764151; 15777548; 15778383; 15842262; 15854776; 15867866; 15879416; 15932345; 15940135; 15946916; 15966209; 15975149; 16038043; 16046876; 16051275; 16061600; 16085746; 16101942; 16109674; 16137548; 16142747; 16148556; 16159630; 16165702; 16174094; 16174099; 16194368; 16239565; 16246938; 16266379; 16273620; 16273622; 16275943; 16283111; 16290232; 16292464; 16331574; 16335952; 16337421; 16344560; 16368002; 16381901; 16385250; 16386288; 16387800; 16409569; 16427140; 16433727; 16437636; 16443672; 16444757; 16446545; 16467036; 16473828; 16492974; 16509825; 16512634; 16520888; 16538169; 16552356; 16611358; 16614348; 16625214; 16698680; 16706818; 16749413; 16751411; 16785528; 16815140; 16836908; 16848791; 16860318; 16873708; 16879054; 16890863; 16893989; 16916546; 16933467; 16950285; 16950521; 17003960; 17007028; 17030237; 17046070; 17052752; 17056323; 17062130; 17067484; 17075287; 17086894; 17087609; 17098305; 17126402; 17187267; 17196641; 17201240; 17205552; 17207357; 17217435; 17259806; 17264400; 17274987; 17304102; 17309585; 17436151; 17438094; 17448042; 17456337; 17471431; 17511783; 17515856; 17565650; 17600225; 17607003; 17617027; 17653770; 17703412; 17802898; 17846597; 17869646; 17877764; 17877801; 17900622; 17913858; 17916440; 17919709; 17925604; 17934216; 17943182; 17949800; 17982638; 18008256; 18040078; 18056918; 18057002; 18067042; 18157711; 18158110; 18174680; 18180316; 18180796; 18182917; 18288274; 18312481; 18315435; 18320914; 18354240; 18385826; 18414664; 18415752; 18417506; 18425216; 18426570; 18458151; 18495781; 18496988; 18497880; 18519568; 18565258; 18571004; 18580445; 18580477; 18596635; 18606699; 18634146; 18664531; 18666712; 18676680; 18691306; 18714537; 18728522; 18767926; 18774388; 18794053; 18810425; 18818748; 18931892; 18938271; 18951711; 18974840; 18974842; 18987746; 18991094; 19006850; 19010986; 19019335; 19027777; 19028820; 19037967; 19046305; 19056867; 19060757; 19096003; 19131662; 19148143; 19170196; 19189651; 19200604; 19210273; 19222419; 19225544; 19242719; 19247692; 19254290; 19258923; 19263529; 19264973; 19275920; 19318422; 19337058; 19346955; 19360901; 19361972; 19365146; 19390489; 19420105; 19423540; 19433913; 19447482; 19466271; 19468702; 19479237; 19500269; 19508433; 19522765; 19527514; 19536153; 19550115; 19559392; 19572148; 19578796; 19584052; 19595045; 19605672; 19625176; 19674346; 19692168; 19701968; 19729601; 19733948; 19741468; 19758335; 19761511; 19795323; 19799036; 19809507; 19824106; 19829130; 19830784; 19845895; 19847953; 19860589; 19892918; 19913121; 19928913; 19948975; 19997857; 20039305; 20085599; 20092898; 20109306; 20109750; 20113368; 20163933; 20179016; 20207250; 20219985; 20227257; 20302606; 20346360; 20363151; 20364047; 20377740; 20381257; 20384875; 20394509; 20395963; 20398919; 20406964; 20430603; 20430725; 20438785; 20452482; 20463618; 20472010; 20472613; 20485444; 20503287; 20532808; 20536280; 20536507; 20555320; 20579716; 20587312; 20603037; 20608916; 20618347; 20628086; 20636398; 20660791; 20673868; 20677014; 20703737; 20717070; 20723409; 20730440; 20826579; 20832340; 20865702; 20964518; 21039068; 21041645; 21048031; 21052690; 21062235; 21063024; 21079949; 21084593; 21118416; 21172039; 21178007; 21191073; 21209279; 21253969; 21257965; 21277522; 21278688; 21293259; 21303362; 21333644; 21361908; 21389010; 21476947; 21489615; 21498585; 21596674; 21633598; 21700881; 21705839; 21722015; 21740312; 21745379; 21799175; 21808991; 21842127; 21885391; 21905503; 21921097; 21948372; 21988832; 22014346; 22015088; 22056216; 22219617; 22232682; 22260507; 22265692; 22363790; 22376040; 22384567; 22445606; 22482418; 22564189; 22648004; 22697010; 22703766; 22737215; 22808111; 22812245; 22937756; 22961048; 22999728; 23000519; 23009036; 23036097; 23036271; 23046822; 23049772; 23079836; 23101184; 23107636; 23121673; 23146639; 23162014; 23162132; 23194293; 23201091; 23206327; 23264655; 23277403; 23338226; 23371544; 23430250; 23510625; 23537804; 23565226; 23582034; 23589304; 23679818; 23741383; 23762319; 23786414; 23824692; 23880187; 23936239; 24044964; 24077340; 24116867; 24172224 CD14 molecule CD14 Bin Zhao, Yue Liu, Oliver He SIGLEC-3 SIGLEC3 p67 WEB: http://www.ncbi.nlm.nih.gov/gene CD33 CD33 molecule 945 19q13.3 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0004872 (EC: TAS, PMID: 10611343); GO_0005515 (EC: IPI, PMID: 10206955); GO_0005886 (EC: TAS, PMID: 3139766); GO_0005887 (EC: TAS, PMID: 3139766); GO_0007155 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10611343); GO_0007267 (EC: TAS, PMID: 10611343); GO_0008285 (EC: TAS, PMID: 10611343); GO_0009897 (EC: IDA) PMID: 1696442; 3139766; 7505004; 7718872; 8454872; 8702538; 9465907; 10206955; 10556798; 10611343; 11320212; 11774609; 11943481; 11964282; 11970770; 12063025; 12144127; 12477932; 15342556; 15388576; 15454492; 15489334; 15611322; 15676214; 16380601; 17662271; 18051367; 18062779; 18085638; 18331725; 18615103; 18767926; 18794057; 18976728; 19259613; 19275586; 19572148; 20147975; 20237496; 20379614; 21048031; 21081841; 21278227; 21329979; 21348573; 21460840; 21460841; 21906983; 21988832; 21993666; 22167654; 22382309; 23444229; 23623698; 23708142; 23946390 CD33 molecule Ensembl:ENSG00000105383 HGNC:1659 HPRD:01165 MIM:159590 Vega:OTTHUMG00000182891 CD33 Bin Zhao, Yue Liu, Oliver He BDPLT10 CHDS7 FAT GP3B GP4 GPIV PASIV SCARB3 WEB: http://www.ncbi.nlm.nih.gov/gene CD36 CD36 molecule (thrombospondin receptor) 948 7q11.2 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0000122 (EC: IEA); GO_0001954 (EC: IDA, PMID: 17416590); GO_0002224 (EC: TAS); GO_0002474 (EC: TAS); GO_0002479 (EC: TAS); GO_0002576 (EC: TAS); GO_0002755 (EC: TAS); GO_0005041 (EC: IMP, PMID: 10772654); GO_0005041 (EC: TAS, PMID: 9568716); GO_0005794 (EC: IEA); GO_0005886 (EC: IDA); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 9568716); GO_0006629 (EC: NAS, PMID: 7518447); GO_0006898 (EC: IMP, PMID: 10772654); GO_0006898 (EC: TAS, PMID: 9568716); GO_0006910 (EC: IEA); GO_0007155 (EC: IEA); GO_0007166 (EC: IEA); GO_0007263 (EC: IDA, PMID: 17416590); GO_0007596 (EC: TAS); GO_0008035 (EC: IEA); GO_0008289 (EC: IDA, PMID: 10772654); GO_0009897 (EC: IEA); GO_0009986 (EC: IDA, PMID: 10772654); GO_0009986 (EC: ISS); GO_0010744 (EC: IMP, PMID: 10772654); GO_0010886 (EC: IEA); GO_0015911 (EC: IDA, PMID: 17416590); GO_0016020 (EC: TAS, PMID: 2468669); GO_0019915 (EC: IMP, PMID: 10772654); GO_0019934 (EC: IDA, PMID: 17416590); GO_0030168 (EC: TAS); GO_0030169 (EC: IDA, PMID: 10772654); GO_0030194 (EC: IEA); GO_0030301 (EC: ISS, PMID: 12376530); GO_0030666 (EC: TAS); GO_0031092 (EC: TAS); GO_0032735 (EC: IEA); GO_0032755 (EC: IEA); GO_0032760 (EC: IEA); GO_0034134 (EC: TAS); GO_0034142 (EC: TAS); GO_0034381 (EC: ISS, PMID: 12376530); GO_0034383 (EC: IMP, PMID: 10772654); GO_0035634 (EC: IEA); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042590 (EC: TAS); GO_0042953 (EC: IMP, PMID: 10772654); GO_0042953 (EC: TAS, PMID: 9568716); GO_0042992 (EC: IEA); GO_0043123 (EC: IEA); GO_0043277 (EC: IEA); GO_0043410 (EC: IEA); GO_0044130 (EC: IEA); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0044539 (EC: IDA); GO_0045087 (EC: TAS); GO_0045121 (EC: IEA); GO_0045335 (EC: TAS); GO_0050431 (EC: ISS); GO_0050731 (EC: IEA); GO_0050830 (EC: IEA); GO_0055096 (EC: IEA); GO_0060100 (EC: IEA); GO_0060907 (EC: IEA); GO_0070053 (EC: ISS); GO_0070892 (EC: IEA); GO_0071221 (EC: IEA); GO_0071222 (EC: IEA); GO_0071223 (EC: IEA); GO_0071447 (EC: IEA); GO_0071813 (EC: IDA, PMID: 9568716); GO_2000121 (EC: IEA); GO_2000334 (EC: IEA); GO_2000379 (EC: IEA) PMID: 1384492; 1715582; 2468669; 2468670; 2473841; 7503937; 7505064; 7518447; 7521304; 7533783; 7682812; 7686693; 7693034; 7693552; 8467233; 8561798; 8696942; 8798390; 9171348; 9334230; 9555943; 9568716; 10391209; 10487979; 10772654; 10772928; 10772961; 10890433; 11238109; 11377606; 11433350; 11602321; 11668637; 11686358; 11714819; 11718687; 11834946; 11867619; 11872368; 11950861; 12023894; 12031598; 12105195; 12164325; 12169456; 12224819; 12376530; 12477932; 12479587; 12496189; 12506336; 12516552; 12576469; 12598312; 12606036; 12618277; 12664607; 12679131; 12690205; 12716760; 12716848; 12732844; 12801610; 12947091; 12968020; 12971464; 14684613; 14699114; 14702039; 14719070; 14729862; 15048167; 15050739; 15059642; 15064117; 15132977; 15167446; 15221799; 15242332; 15282206; 15339698; 15342556; 15478802; 15489334; 15671915; 15677505; 15735450; 15780035; 15860439; 15897321; 15915335; 15933580; 15978955; 15979077; 16002039; 16037098; 16099393; 16219805; 16263699; 16276419; 16299313; 16344560; 16453284; 16515687; 16556603; 16622019; 16645727; 16670153; 16670819; 16838191; 16870193; 16880211; 16887969; 16908526; 16911630; 16952981; 17067553; 17071479; 17084382; 17311893; 17346709; 17380316; 17412877; 17416590; 17440173; 17496152; 17572512; 17573918; 17581812; 17619827; 17673938; 17710630; 17716309; 17854769; 17888147; 17900273; 17905828; 17924847; 18000176; 18029348; 18035074; 18053692; 18067591; 18263877; 18285332; 18288886; 18299339; 18305138; 18353783; 18441389; 18458151; 18462250; 18497330; 18514070; 18550349; 18558917; 18582374; 18660489; 18671254; 18827892; 18844973; 18981136; 19016618; 19055786; 19065049; 19088437; 19116451; 19136129; 19144874; 19156623; 19175917; 19185504; 19190027; 19203752; 19350111; 19369259; 19403559; 19413744; 19454037; 19489681; 19578796; 19640849; 19667111; 19718657; 19740737; 19864601; 19865095; 19876004; 19893500; 19913121; 19948975; 19996318; 20015873; 20023206; 20037584; 20075072; 20113368; 20139232; 20157514; 20223461; 20333725; 20408759; 20408954; 20414830; 20416077; 20459687; 20485444; 20628086; 20629037; 20637247; 20660057; 20664056; 20684828; 20701912; 20722468; 20935172; 20939828; 20946164; 20947105; 20966904; 20966915; 21091228; 21145461; 21155254; 21203512; 21228269; 21250778; 21262584; 21270117; 21346626; 21378271; 21383152; 21390226; 21437286; 21454644; 21462325; 21478428; 21547502; 21696539; 21727988; 21808142; 21832049; 21835916; 21854984; 21890620; 21949655; 21988832; 22047506; 22050542; 22075538; 22106368; 22113854; 22240721; 22247259; 22275803; 22423221; 22430143; 22558273; 22588808; 22653277; 22687273; 22763563; 22795952; 22869067; 22890011; 22909232; 22993001; 23119050; 23206327; 23213279; 23233532; 23249574; 23427331; 23603908; 23656756; 23726366; 23748423; 23792019; 23817509; 23844572; 23856131; 24009511; 24062612; 24090054; 24284794 CD36 molecule (thrombospondin receptor) Ensembl:ENSG00000135218 HGNC:1663 HPRD:01430 MIM:173510 Vega:OTTHUMG00000155383 CD36 Bin Zhao, Yue Liu, Oliver He CDC2 CDC28A P34CDC2 WEB: http://www.ncbi.nlm.nih.gov/gene CDK1 cyclin-dependent kinase 1 983 10q21.1 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0000082 (EC: TAS); GO_0000083 (EC: TAS); GO_0000086 (EC: TAS); GO_0000165 (EC: TAS); GO_0000186 (EC: TAS); GO_0000187 (EC: TAS); GO_0000226 (EC: TAS); GO_0000278 (EC: TAS); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004672 (EC: NAS, PMID: 9001210); GO_0004674 (EC: IDA, PMID: 19879842); GO_0004693 (EC: IDA, PMID: 11069302); GO_0004693 (EC: TAS); GO_0005515 (EC: IPI, PMID: 10373560); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA); GO_0005739 (EC: TAS, PMID: 19917720); GO_0005815 (EC: IEA); GO_0005829 (EC: TAS); GO_0005876 (EC: IDA, PMID: 11069302); GO_0006260 (EC: TAS); GO_0006281 (EC: TAS); GO_0006461 (EC: IEA); GO_0006915 (EC: IEA); GO_0007067 (EC: IEA); GO_0007077 (EC: TAS); GO_0007095 (EC: IEA); GO_0007098 (EC: TAS, PMID: 19364923); GO_0007173 (EC: TAS); GO_0007264 (EC: TAS); GO_0007265 (EC: TAS); GO_0007344 (EC: TAS); GO_0007411 (EC: TAS); GO_0007569 (EC: IEA); GO_0008286 (EC: TAS); GO_0008353 (EC: IDA, PMID: 12721286); GO_0008543 (EC: TAS); GO_0009636 (EC: IEA); GO_0010628 (EC: IEA); GO_0014038 (EC: TAS, PMID: 17200138); GO_0014070 (EC: IEA); GO_0014075 (EC: IEA); GO_0014823 (EC: IEA); GO_0016477 (EC: TAS, PMID: 17200138); GO_0018105 (EC: IDA, PMID: 19879842); GO_0030261 (EC: IEA); GO_0030332 (EC: IEA); GO_0030496 (EC: IDA, PMID: 11069302); GO_0030544 (EC: IEA); GO_0030855 (EC: IEP); GO_0031100 (EC: IEA); GO_0031145 (EC: TAS); GO_0033160 (EC: IEA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0034501 (EC: IDA, PMID: 18195732); GO_0035173 (EC: IEA); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042493 (EC: IEA); GO_0043066 (EC: IDA, PMID: 11069302); GO_0045087 (EC: TAS); GO_0045471 (EC: IEA); GO_0045740 (EC: IEA); GO_0045931 (EC: IEA); GO_0045995 (EC: TAS); GO_0046686 (EC: IEA); GO_0046688 (EC: IEA); GO_0048011 (EC: TAS); GO_0048678 (EC: IEA); GO_0051403 (EC: TAS); GO_0051437 (EC: TAS); GO_0051439 (EC: TAS); GO_0055015 (EC: IEA); GO_0060045 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070301 (EC: IEA) PMID: 914146; 1310466; 1318195; 1384126; 1388288; 1400350; 1406653; 1425574; 1628647; 1717476; 1748630; 1756735; 1828290; 1916766; 1939057; 2013279; 2183353; 2227411; 2344612; 2473839; 2538242; 2541912; 2570636; 2686978; 3289755; 3553962; 7474080; 7474100; 7494303; 7499230; 7578274; 7590285; 7592773; 7635160; 7666531; 7673335; 7716549; 7724583; 7737117; 7769006; 7790358; 7799941; 7822264; 7876309; 7902715; 7903056; 7925482; 7944411; 7949095; 7969176; 7983050; 8034666; 8051108; 8051175; 8070405; 8084605; 8087847; 8119945; 8125092; 8127873; 8242750; 8325880; 8376365; 8397206; 8397207; 8404858; 8423786; 8428596; 8440392; 8463339; 8475101; 8491187; 8524869; 8548803; 8565853; 8626512; 8626527; 8631817; 8652557; 8662825; 8663071; 8672508; 8806671; 8910336; 9001210; 9053846; 9069267; 9094673; 9109675; 9126608; 9130708; 9141461; 9188632; 9199321; 9235942; 9242535; 9244350; 9247342; 9258347; 9268380; 9271440; 9295339; 9315091; 9315635; 9398320; 9467962; 9515786; 9520381; 9524113; 9525956; 9560267; 9575153; 9585407; 9600099; 9614189; 9668078; 9725910; 9733650; 9753325; 9774639; 9885575; 9891079; 9926943; 9988268; 9990288; 10077596; 10339564; 10359664; 10362260; 10373560; 10383391; 10395539; 10403367; 10497277; 10502411; 10504341; 10524633; 10564259; 10602502; 10636877; 10656688; 10712923; 10716937; 10747892; 10764745; 10766737; 10767298; 10769027; 10793135; 10825186; 10864927; 10884347; 10924145; 10938080; 10958988; 10973963; 11034995; 11069302; 11076863; 11076968; 11113134; 11113184; 11135364; 11136719; 11259605; 11278541; 11278991; 11285280; 11310559; 11326318; 11327730; 11331587; 11395479; 11444800; 11470801; 11504921; 11516829; 11520933; 11531413; 11549262; 11559705; 11574543; 11584018; 11598127; 11683421; 11687586; 11774038; 11779217; 11782384; 11836499; 11861764; 11878934; 11895447; 11901153; 11953320; 11980914; 11986303; 12058066; 12077309; 12107172; 12124778; 12145207; 12151413; 12177195; 12186947; 12190313; 12200623; 12221128; 12361598; 12372621; 12397081; 12407107; 12411508; 12450396; 12468530; 12477932; 12525641; 12551973; 12556484; 12569090; 12569365; 12586835; 12604359; 12612056; 12612082; 12613668; 12648761; 12676926; 12721286; 12742823; 12771130; 12775724; 12791267; 12810701; 12832492; 12839990; 12852856; 12853968; 12881709; 12884029; 12912980; 14499622; 14551205; 14635192; 14645578; 14654553; 14697231; 14993212; 15014043; 15016823; 15024056; 15030318; 15050687; 15070733; 15073847; 15082718; 15125835; 15142377; 15145941; 15147269; 15175024; 15181148; 15215233; 15265780; 15276183; 15311285; 15317660; 15345747; 15367677; 15368451; 15474478; 15489334; 15489336; 15525513; 15525677; 15531913; 15541388; 15578977; 15582998; 15591787; 15592455; 15604258; 15635413; 15662526; 15674323; 15678101; 15725353; 15735702; 15735705; 15767402; 15780175; 15782160; 15790566; 15800651; 15817944; 15888452; 15951569; 15989971; 16009130; 16036217; 16109376; 16118207; 16142332; 16159883; 16192727; 16196087; 16198290; 16205633; 16226712; 16237118; 16247472; 16258277; 16344560; 16354571; 16371510; 16377132; 16381901; 16385451; 16407259; 16427064; 16458891; 16462731; 16465393; 16474839; 16478538; 16519687; 16533053; 16565220; 16629900; 16682949; 16760428; 16784539; 16807237; 16880735; 16880739; 16888198; 16998479; 17011204; 17012222; 17013563; 17043241; 17098733; 17159347; 17171635; 17172867; 17192257; 17200138; 17242184; 17274640; 17327911; 17349584; 17351640; 17359356; 17373700; 17386261; 17419986; 17431037; 17433108; 17466630; 17472438; 17474786; 17488622; 17498878; 17525531; 17540176; 17586317; 17636382; 17679094; 17681274; 17725712; 17906618; 17960875; 18003885; 18025303; 18029348; 18056802; 18069625; 18195732; 18201571; 18230152; 18245089; 18247328; 18271526; 18272572; 18272575; 18329369; 18337751; 18347064; 18356527; 18372919; 18408765; 18434602; 18445273; 18450493; 18457437; 18471975; 18477460; 18480403; 18490441; 18514189; 18550795; 18560763; 18568422; 18593881; 18615582; 18635963; 18655026; 18781797; 18799590; 18950845; 19048596; 19056867; 19061641; 19066288; 19134343; 19158392; 19162005; 19223178; 19275580; 19275583; 19275586; 19275588; 19303298; 19344781; 19364923; 19369249; 19375851; 19454010; 19458171; 19471022; 19473963; 19483727; 19509060; 19615732; 19664338; 19683496; 19687009; 19723060; 19725879; 19737929; 19738201; 19786724; 19789190; 19815027; 19837665; 19879842; 19884882; 19917720; 20062077; 20068230; 20068231; 20126263; 20169205; 20171170; 20181698; 20228808; 20360007; 20360068; 20367638; 20368335; 20368358; 20379221; 20395957; 20404109; 20412769; 20439461; 20444701; 20508983; 20526282; 20581839; 20711190; 20733055; 20739936; 20808790; 20810654; 20890132; 20935635; 20937773; 20956543; 20974803; 20974812; 21041660; 21059642; 21081492; 21081666; 21120602; 21123648; 21131960; 21135039; 21139048; 21148318; 21262764; 21308745; 21319273; 21325631; 21379580; 21406398; 21454540; 21488187; 21489275; 21498573; 21504622; 21522128; 21525341; 21569376; 21659531; 21693764; 21712819; 21743465; 21767532; 21813648; 21840486; 21871177; 21871181; 21875946; 21878504; 21878640; 21887332; 21890473; 21900237; 21900495; 21906983; 21907836; 21918813; 21924351; 21925791; 21951856; 21952639; 21963094; 21987572; 21987589; 21988832; 21998300; 22024133; 22053931; 22071694; 22101338; 22137483; 22158041; 22163316; 22266860; 22268729; 22407595; 22482362; 22496227; 22505724; 22552942; 22580043; 22623428; 22689984; 22718829; 22726437; 22768111; 22784093; 22814604; 22848730; 22863883; 22871736; 22907750; 22939629; 22949227; 22962268; 22965228; 23000965; 23045552; 23264621; 23330000; 23355470; 23383273; 23455152; 23471882; 23518499; 23525902; 23532886; 23543736; 23602568; 23619525; 23667531; 23720738; 23738518; 23775624; 23776131; 23814058; 23824909; 23901111; 23908594; 23921553; 23933584; 23956138; 23958962; 23966160; 23990466; 24101154; 24137814; 24248602; 24250222; 24457600 cyclin-dependent kinase 1 Ensembl:ENSG00000170312 HGNC:1722 HPRD:00302 MIM:116940 Vega:OTTHUMG00000018290 CDK1 Bin Zhao, Yue Liu, Oliver He CDC42Hs G25K WEB: http://www.ncbi.nlm.nih.gov/gene CDC42 cell division cycle 42 998 RP1-224A6.5 1p36.1 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000139 (EC: ISS); GO_0002040 (EC: IEA); GO_0003161 (EC: IEA); GO_0003334 (EC: IEA); GO_0003924 (EC: TAS, PMID: 11035016); GO_0005515 (EC: IPI, PMID: 10051605); GO_0005525 (EC: IEA); GO_0005737 (EC: IDA, PMID: 11260256); GO_0005815 (EC: IEA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 11260256); GO_0005886 (EC: TAS); GO_0006184 (EC: TAS, PMID: 11035016); GO_0007030 (EC: ISS); GO_0007088 (EC: IEA); GO_0007097 (EC: IEA); GO_0007163 (EC: TAS, PMID: 11260256); GO_0007173 (EC: TAS); GO_0007264 (EC: TAS); GO_0007411 (EC: TAS); GO_0007596 (EC: TAS); GO_0010628 (EC: IEA); GO_0010629 (EC: IEA); GO_0016020 (EC: IDA, PMID: 11807099); GO_0019901 (EC: IDA, PMID: 19039103); GO_0019901 (EC: IPI); GO_0021762 (EC: IEP); GO_0030036 (EC: IDA, PMID: 11035016); GO_0030141 (EC: IEA); GO_0030175 (EC: IDA, PMID: 11035016); GO_0030225 (EC: TAS, PMID: 11260256); GO_0030496 (EC: IDA, PMID: 15642749); GO_0030742 (EC: IEA); GO_0031069 (EC: IEA); GO_0031274 (EC: IDA, PMID: 11035016); GO_0031295 (EC: TAS); GO_0031333 (EC: IPI, PMID: 11584266); GO_0031424 (EC: IEA); GO_0031435 (EC: IEA); GO_0031647 (EC: IEA); GO_0031996 (EC: IPI, PMID: 12612085); GO_0032467 (EC: IMP, PMID: 15642749); GO_0033138 (EC: IEA); GO_0034191 (EC: IPI, PMID: 16443932); GO_0034332 (EC: IEA); GO_0034613 (EC: IEA); GO_0035088 (EC: IEA); GO_0035264 (EC: IEA); GO_0038096 (EC: TAS); GO_0042059 (EC: TAS); GO_0042176 (EC: IEA); GO_0042692 (EC: TAS); GO_0042802 (EC: IPI, PMID: 9748241); GO_0043005 (EC: IDA); GO_0043025 (EC: IDA); GO_0043497 (EC: IEA); GO_0043525 (EC: IEA); GO_0043552 (EC: IEA); GO_0045087 (EC: TAS); GO_0045177 (EC: IEA); GO_0045740 (EC: IEA); GO_0045859 (EC: IEA); GO_0046330 (EC: IEA); GO_0046847 (EC: IEA); GO_0048554 (EC: IEA); GO_0048664 (EC: IEA); GO_0051017 (EC: IEA); GO_0051056 (EC: TAS); GO_0051149 (EC: TAS); GO_0051233 (EC: IDA, PMID: 15642749); GO_0051489 (EC: IDA, PMID: 14978216); GO_0051683 (EC: ISS); GO_0051835 (EC: IEA); GO_0051988 (EC: IMP, PMID: 15642749); GO_0060047 (EC: IEA); GO_0060070 (EC: IEA); GO_0060661 (EC: IEA); GO_0060684 (EC: IEA); GO_0060789 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0071338 (EC: IEA); GO_0072384 (EC: ISS); GO_0072686 (EC: IDA, PMID: 15642749); GO_0090135 (EC: IEA); GO_0090136 (EC: IEA); GO_0090316 (EC: IEA); GO_1900026 (EC: IDA, PMID: 11807099) PMID: 1898776; 1956381; 2122236; 2124704; 2496687; 7493928; 7513047; 7547927; 7629060; 7665558; 7738010; 7744004; 8034624; 8107774; 8625410; 8643625; 8670801; 8702968; 8755667; 8756646; 8798539; 8889548; 8943016; 8969170; 8994833; 9032261; 9079650; 9082982; 9113980; 9182573; 9210375; 9220962; 9262406; 9268338; 9338791; 9381982; 9407060; 9418861; 9422512; 9427749; 9490022; 9535835; 9535855; 9582072; 9642115; 9660763; 9705280; 9742969; 9748241; 9760238; 9786927; 9799233; 9822598; 9846874; 9860974; 10051605; 10068673; 10211824; 10320322; 10360578; 10360579; 10366564; 10480361; 10490598; 10551883; 10587647; 10676816; 10684602; 10713100; 10713183; 10724160; 10733591; 10747870; 10749885; 10781580; 10799501; 10799524; 10802735; 10816584; 10818149; 10854437; 10873802; 10934474; 10954424; 10954711; 10967094; 10975523; 11035016; 11090627; 11130076; 11157984; 11162552; 11257000; 11260256; 11278572; 11284700; 11287617; 11331876; 11394904; 11431473; 11432776; 11438723; 11583574; 11584266; 11584276; 11672528; 11696321; 11756552; 11773441; 11807099; 11822867; 11839748; 11884513; 11889037; 11907271; 11943145; 11948177; 11973651; 11998687; 12006984; 12032833; 12093730; 12110184; 12115629; 12172552; 12181570; 12235133; 12270144; 12369824; 12376551; 12421766; 12426222; 12432077; 12446789; 12453877; 12456510; 12477932; 12504591; 12511425; 12538863; 12547822; 12584113; 12595527; 12606577; 12612085; 12650940; 12745076; 12767056; 12769846; 12819203; 12824775; 12857875; 12860998; 12879077; 12887916; 12887922; 12887923; 12900413; 12901880; 12915445; 12928366; 12944407; 12960245; 12960248; 12972601; 14505571; 14530271; 14563854; 14597672; 14656933; 14676191; 14699061; 14701795; 14733946; 14749388; 14970210; 14978216; 15023524; 15075243; 15085137; 15102814; 15121898; 15123659; 15123662; 15133042; 15147912; 15187089; 15194684; 15260990; 15265891; 15287724; 15304341; 15306850; 15355962; 15361624; 15451670; 15472119; 15485837; 15489334; 15616194; 15642749; 15649357; 15652341; 15652748; 15655247; 15713627; 15723050; 15728253; 15735674; 15761153; 15793569; 15803130; 15821030; 15822942; 15824104; 15833843; 15834156; 15864311; 15901767; 15923648; 16169070; 16189514; 16201754; 16204230; 16228294; 16246732; 16253996; 16293614; 16322481; 16356860; 16407834; 16443932; 16678097; 16687395; 16710414; 16849480; 16864657; 16880514; 16930532; 16983070; 17038317; 17074883; 17115031; 17254974; 17300218; 17301947; 17346701; 17353931; 17356711; 17513457; 17513786; 17517067; 17521326; 17538024; 17567985; 17664338; 17693642; 17702745; 17971488; 17976533; 18045877; 18056264; 18056353; 18057010; 18235104; 18245386; 18245474; 18287089; 18319301; 18325348; 18334926; 18348980; 18363964; 18403635; 18432521; 18541383; 18541478; 18541705; 18552504; 18565850; 18575765; 18586681; 18624398; 18628988; 18656530; 18728402; 18835169; 18838868; 18922799; 18937283; 18974134; 19001128; 19039103; 19056867; 19109421; 19273597; 19307303; 19322201; 19356586; 19416857; 19435802; 19454477; 19463088; 19473971; 19561083; 19596003; 19622753; 19635823; 19640983; 19641023; 19667218; 19692568; 19709124; 19710257; 19718053; 19726670; 19752396; 19778949; 19787194; 19819966; 19826000; 19933840; 19934222; 20056178; 20067638; 20086093; 20130240; 20215637; 20403997; 20530489; 20545942; 20631255; 20696164; 20730103; 20806065; 20849862; 20873783; 20936779; 20945370; 21036919; 21048939; 21139048; 21165582; 21167153; 21186079; 21221794; 21240187; 21295525; 21302623; 21311754; 21356349; 21435037; 21454543; 21562048; 21603851; 21613211; 21618528; 21667996; 21685891; 21866627; 21890473; 21900206; 21906983; 21952626; 21963094; 21988832; 22023324; 22053931; 22092654; 22093623; 22126964; 22213037; 22266952; 22318733; 22341450; 22362774; 22385474; 22393238; 22505724; 22589722; 22608513; 22610502; 22683270; 22719838; 22770822; 22796473; 22821962; 22844345; 22863883; 22891260; 22939629; 23000965; 23029280; 23142484; 23148235; 23178712; 23197258; 23295348; 23337504; 23358418; 23455922; 23521319; 23562274; 23583380; 23606532; 23622765; 23625752; 23696594; 23718289; 23884297; 23894465; 23936510; 24025765; 24178298; 24250222; 24256571; 24379416; 24413169 cell division cycle 42 Ensembl:ENSG00000070831 HGNC:1736 HPRD:00309 MIM:116952 Vega:OTTHUMG00000002753 CDC42 Bin Zhao, Yue Liu, Oliver He CD325 CDHN CDw325 NCAD WEB: http://www.ncbi.nlm.nih.gov/gene CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1000 18q11.2 20140408 9606 18 protein-coding Official from a nomenclature committee GO_0005509 (EC: IEA); GO_0005515 (EC: IPI, PMID: 17057644); GO_0005886 (EC: TAS); GO_0005911 (EC: IDA, PMID: 7650039); GO_0005913 (EC: IDA, PMID: 19101069); GO_0005916 (EC: IEA); GO_0007155 (EC: TAS, PMID: 2384753); GO_0007156 (EC: IEA); GO_0007157 (EC: IEA); GO_0008013 (EC: TAS, PMID: 16344550); GO_0014704 (EC: ISS); GO_0016021 (EC: IEA); GO_0016324 (EC: IEA); GO_0016339 (EC: IEA); GO_0016342 (EC: IDA, PMID: 7650039); GO_0016477 (EC: IEA); GO_0019903 (EC: IEA); GO_0030027 (EC: IEA); GO_0034329 (EC: TAS); GO_0034332 (EC: TAS); GO_0042692 (EC: TAS); GO_0043410 (EC: IEA); GO_0045202 (EC: IEA); GO_0045216 (EC: TAS); GO_0045294 (EC: IPI, PMID: 7650039); GO_0045295 (EC: IPI, PMID: 7650039); GO_0048514 (EC: IEA); GO_0051146 (EC: IEA); GO_0051149 (EC: TAS); GO_0090090 (EC: IEA) PMID: 1500442; 1639850; 2216790; 2384753; 7650039; 7731968; 7806582; 7959764; 7995652; 8074697; 9168198; 9199196; 9219219; 9508779; 9542583; 9615235; 9971746; 10662782; 10818391; 10862698; 11058098; 11106648; 11136230; 11329013; 11729199; 11790800; 11821434; 11835406; 11996105; 12057916; 12077367; 12095980; 12151522; 12377785; 12398894; 12438242; 12477932; 12503652; 12531901; 12545205; 12604612; 12615965; 12634428; 12639940; 13678586; 14515347; 14559901; 14625392; 14675278; 15146197; 15153430; 15192701; 15217949; 15252840; 15263022; 15331629; 15355896; 15527101; 15541732; 15648948; 15701645; 15713751; 15731052; 15774907; 15855653; 15923648; 15987741; 16007225; 16091424; 16149052; 16173043; 16212419; 16258702; 16344550; 16344560; 16371504; 16596172; 16675571; 16707106; 16819153; 16969099; 17008425; 17031402; 17057644; 17060906; 17171299; 17178870; 17229887; 17255093; 17348027; 17389597; 17512904; 17646933; 17668445; 17868645; 17944884; 18269586; 18362184; 18414176; 18495274; 18622386; 18801083; 18978678; 18979298; 19033391; 19043453; 19070520; 19101069; 19124205; 19167335; 19190132; 19222093; 19324354; 19339270; 19448425; 19501458; 19530221; 19580633; 19584275; 19898423; 19919954; 20082286; 20116358; 20117462; 20137108; 20139113; 20204300; 20233707; 20308060; 20371349; 20379614; 20388391; 20451421; 20605145; 20630685; 20634891; 20664068; 20735983; 20738806; 20811707; 21042713; 21057494; 21070371; 21080917; 21084302; 21122409; 21123580; 21139048; 21156175; 21176502; 21177868; 21315068; 21315259; 21423153; 21596022; 21777276; 21785870; 21810271; 21828122; 21845495; 21852538; 21855541; 21858092; 21875946; 21890473; 21988832; 21990317; 22040951; 22072429; 22166980; 22275437; 22344255; 22360503; 22365631; 22385354; 22405962; 22490800; 22490896; 22576709; 22615994; 22632162; 22637581; 22767590; 22810307; 22846995; 22888908; 22912891; 22939629; 22976797; 23000965; 23086683; 23240619; 23251661; 23276695; 23290789; 23314748; 23314859; 23321619; 23398382; 23420609; 23438504; 23520479; 23626784; 23626818; 23733927; 23899519; 23900215; 24023788; 24148886; 24227724 cadherin 2, type 1, N-cadherin (neuronal) Ensembl:ENSG00000170558 HGNC:1759 HPRD:00226 MIM:114020 Vega:OTTHUMG00000059940 CDH2 Bin Zhao, Yue Liu, Oliver He CMM3 PSK-J3 WEB: http://www.ncbi.nlm.nih.gov/gene CDK4 cyclin-dependent kinase 4 1019 12q14 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000082 (EC: IMP, PMID: 7603984); GO_0000278 (EC: TAS); GO_0000307 (EC: IDA, PMID: 17420273); GO_0000785 (EC: IDA, PMID: 18827403); GO_0004693 (EC: IDA, PMID: 8114739); GO_0005515 (EC: IPI, PMID: 11896535); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA, PMID: 16109376); GO_0005654 (EC: TAS); GO_0005667 (EC: IEA); GO_0005730 (EC: IDA, PMID: 18827403); GO_0005829 (EC: IDA, PMID: 18827403); GO_0005829 (EC: TAS); GO_0005923 (EC: IEA); GO_0006468 (EC: IDA, PMID: 8114739); GO_0007165 (EC: IEA); GO_0007623 (EC: IEA); GO_0008284 (EC: IMP, PMID: 7603984); GO_0009636 (EC: IEA); GO_0010288 (EC: IEA); GO_0010468 (EC: IMP, PMID: 17420273); GO_0010971 (EC: IDA, PMID: 19124461); GO_0030332 (EC: IPI, PMID: 19124461); GO_0031100 (EC: IEA); GO_0031965 (EC: IDA, PMID: 18827403); GO_0032403 (EC: IEA); GO_0033574 (EC: IEA); GO_0042493 (EC: IGI, PMID: 18291362); GO_0043065 (EC: IEA); GO_0045727 (EC: IEA); GO_0045793 (EC: IEA); GO_0048146 (EC: IMP, PMID: 17420273); GO_0048471 (EC: IEA); GO_0051301 (EC: IEA); GO_0055093 (EC: IEA); GO_0071157 (EC: IDA, PMID: 19124461) PMID: 2948189; 7478582; 7568034; 7603984; 7606365; 7652577; 7739547; 7739548; 8001816; 8078588; 8101826; 8114739; 8139570; 8221695; 8259215; 8275715; 8449399; 8528263; 8619474; 8622677; 8626527; 8647086; 8662825; 8666233; 8703009; 8741839; 8756624; 8805225; 8867812; 8978686; 8999999; 9003781; 9106657; 9110174; 9111314; 9139732; 9150368; 9163429; 9178893; 9190208; 9192850; 9199321; 9228064; 9244350; 9311594; 9311993; 9315635; 9372967; 9380698; 9396813; 9425228; 9464540; 9482104; 9529249; 9545286; 9632134; 9658399; 9716181; 9837900; 9840932; 10022835; 10049762; 10198259; 10202152; 10342870; 10353443; 10359664; 10447003; 10486249; 10491434; 10499802; 10580009; 10585280; 10601020; 10602502; 10639311; 10713676; 10719365; 10748174; 10788489; 10908655; 11120786; 11132966; 11157749; 11254678; 11254741; 11291051; 11310559; 11358847; 11360184; 11395479; 11426564; 11556834; 11668523; 11684017; 11779854; 11828258; 11867521; 11884610; 11896535; 11900540; 11940657; 11971966; 11982759; 12006580; 12036888; 12036906; 12077343; 12082615; 12130539; 12190313; 12357246; 12383116; 12477932; 12509456; 12519773; 12529334; 12531694; 12545164; 12565795; 12601350; 12676926; 12680219; 12684681; 12731669; 12857727; 12949733; 14641107; 14646596; 14647432; 14672406; 14694185; 14701845; 14754892; 15003538; 15004027; 15024701; 15050687; 15065884; 15147269; 15169570; 15169919; 15208653; 15232106; 15241418; 15480536; 15489334; 15505422; 15558030; 15695403; 15761153; 15797629; 15821902; 15860862; 15880589; 15922743; 15998794; 16109376; 16169070; 16189514; 16205633; 16326706; 16413469; 16449650; 16476733; 16582606; 16601140; 16690963; 16758952; 16782892; 16913845; 16949366; 16962592; 16985050; 17015477; 17043357; 17047042; 17053782; 17072968; 17139501; 17205132; 17274640; 17304504; 17334399; 17353931; 17374178; 17409409; 17420273; 17505264; 17517622; 17530187; 17540176; 17556661; 17620599; 17664862; 17881001; 17892862; 17895748; 17909018; 17955473; 18006822; 18023021; 18174243; 18202766; 18281541; 18285702; 18291362; 18361427; 18413728; 18484097; 18507837; 18537972; 18615582; 18624751; 18628440; 18632627; 18636124; 18676680; 18703151; 18710949; 18769160; 18776921; 18781797; 18799615; 18803811; 18823025; 18827403; 18839518; 18850315; 18949380; 19011513; 19040567; 19075005; 19080374; 19124461; 19124506; 19141386; 19143767; 19170196; 19197163; 19225156; 19237555; 19237565; 19238106; 19258477; 19320462; 19320745; 19327170; 19430707; 19447967; 19470470; 19487459; 19556892; 19625176; 19626636; 19634152; 19692168; 19695727; 19737942; 19738611; 19861461; 19890848; 19913121; 19917880; 19935879; 19960406; 20020773; 20100483; 20102411; 20179208; 20196171; 20354191; 20453000; 20534551; 20581865; 20601938; 20618617; 20628086; 20713460; 20736297; 20819778; 20837141; 20842456; 20939487; 20951943; 21042715; 21048031; 21051013; 21053367; 21062975; 21085193; 21099295; 21139048; 21145461; 21148318; 21278246; 21317707; 21325289; 21336260; 21383967; 21412176; 21419342; 21426400; 21455311; 21477379; 21559334; 21593195; 21675959; 21715330; 21777578; 21832049; 21890473; 21900206; 21903422; 21906983; 21952639; 21988832; 22052559; 22053931; 22094256; 22158041; 22289176; 22301498; 22301501; 22315411; 22357515; 22394260; 22418736; 22505724; 22654103; 22733811; 22825724; 22905154; 22939624; 22939629; 23174577; 23292829; 23324348; 23383273; 23384855; 23455922; 23462184; 23469153; 23529275; 23543736; 23602568; 23622515; 23684928; 23707388; 23707559; 23718855; 23737530; 23737759; 23761023; 23776583; 24163379 cyclin-dependent kinase 4 Ensembl:ENSG00000135446 HGNC:1773 HPRD:00447 MIM:123829 Vega:OTTHUMG00000170382 CDK4 Bin Zhao, Yue Liu, Oliver He PSSALRE WEB: http://www.ncbi.nlm.nih.gov/gene CDK5 cyclin-dependent kinase 5 1020 7q36 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0001764 (EC: TAS); GO_0001963 (EC: IEA); GO_0002039 (EC: IEA); GO_0004672 (EC: TAS, PMID: 1639063); GO_0004674 (EC: IDA); GO_0004674 (EC: ISS); GO_0004674 (EC: TAS); GO_0004693 (EC: ISS); GO_0005176 (EC: ISS); GO_0005515 (EC: IPI, PMID: 12223541); GO_0005524 (EC: IEA); GO_0005634 (EC: ISS); GO_0005737 (EC: ISS); GO_0005829 (EC: TAS); GO_0006886 (EC: IEA); GO_0006913 (EC: IEA); GO_0007160 (EC: IEA); GO_0007268 (EC: TAS); GO_0007411 (EC: TAS); GO_0007416 (EC: TAS); GO_0007519 (EC: IEA); GO_0007596 (EC: TAS); GO_0008045 (EC: IEA); GO_0008283 (EC: TAS, PMID: 8090221); GO_0008542 (EC: IEA); GO_0009790 (EC: ISS); GO_0014044 (EC: IEA); GO_0014069 (EC: ISS); GO_0016020 (EC: ISS); GO_0016079 (EC: TAS); GO_0016301 (EC: ISS); GO_0016310 (EC: IDA); GO_0016533 (EC: IEA); GO_0018105 (EC: IDA); GO_0018107 (EC: IEA); GO_0019233 (EC: IEA); GO_0021697 (EC: IEA); GO_0021766 (EC: IEA); GO_0021819 (EC: IEA); GO_0021954 (EC: IEA); GO_0022038 (EC: IEA); GO_0030027 (EC: IEA); GO_0030054 (EC: IEA); GO_0030175 (EC: IEA); GO_0030182 (EC: ISS); GO_0030182 (EC: TAS); GO_0030334 (EC: IEA); GO_0030424 (EC: ISS); GO_0030425 (EC: ISS); GO_0030426 (EC: ISS); GO_0030517 (EC: IEA); GO_0030549 (EC: ISS); GO_0030866 (EC: IEA); GO_0031175 (EC: ISS); GO_0031397 (EC: IEA); GO_0031594 (EC: ISS); GO_0031914 (EC: IEA); GO_0032092 (EC: IEA); GO_0032801 (EC: IEA); GO_0033136 (EC: IEA); GO_0035249 (EC: IEA); GO_0035418 (EC: IEA); GO_0042981 (EC: TAS); GO_0043025 (EC: ISS); GO_0043113 (EC: IEA); GO_0043125 (EC: ISS); GO_0043204 (EC: IEA); GO_0043525 (EC: ISS); GO_0045055 (EC: IEA); GO_0045211 (EC: IEA); GO_0045786 (EC: IEA); GO_0045860 (EC: IEA); GO_0045892 (EC: IMP); GO_0045956 (EC: IEA); GO_0046777 (EC: IEA); GO_0046826 (EC: IEA); GO_0046875 (EC: IEA); GO_0048148 (EC: IEA); GO_0048167 (EC: ISS); GO_0048167 (EC: TAS); GO_0048488 (EC: TAS); GO_0048675 (EC: TAS); GO_0048709 (EC: IDA, PMID: 18042622); GO_0048813 (EC: IEA); GO_0050321 (EC: ISS); GO_0051301 (EC: IEA); GO_0051402 (EC: TAS); GO_0060079 (EC: IEA); GO_0061001 (EC: ISS); GO_0070509 (EC: IEA); GO_0071156 (EC: TAS); GO_0090314 (EC: IEA); GO_2000251 (EC: TAS); GO_2000273 (EC: ISS) PMID: 1181841; 1330687; 1639063; 7566346; 7834371; 7949095; 8090221; 8090222; 8275715; 8702879; 8764598; 8891282; 9013862; 9038181; 9150368; 9199504; 9244350; 9353289; 9396813; 9422379; 9478941; 9545286; 9546672; 9565682; 9596352; 9614189; 9735171; 9771888; 9832145; 10049762; 10500146; 10544291; 10604473; 10683146; 10721722; 10762698; 10884347; 10896159; 10915792; 10936190; 10995546; 11104762; 11113134; 11163260; 11168528; 11181841; 11254741; 11278541; 11311121; 11320080; 11389014; 11483158; 11516829; 11583627; 11604394; 11675505; 11684694; 11733001; 11741927; 11743029; 11784720; 11823425; 11865137; 11882646; 11955625; 12056836; 12064478; 12071639; 12077184; 12084709; 12154070; 12223541; 12226093; 12372285; 12372407; 12387894; 12435421; 12477932; 12491158; 12690205; 12691662; 12765608; 12769842; 12796778; 12824184; 12826674; 12832492; 12832520; 12855954; 12963086; 12970441; 12972605; 14521924; 14704270; 14741103; 15013773; 15030318; 15123618; 15178331; 15342556; 15345747; 15489224; 15489334; 15492003; 15652488; 15741232; 15790807; 15834155; 15890360; 15911879; 15917097; 16327995; 16356933; 16407256; 16413130; 16519508; 16712791; 16862120; 17036052; 17045592; 17060323; 17078951; 17121855; 17145757; 17290217; 17327227; 17419807; 17491008; 17493033; 17581253; 17591690; 17611284; 17713927; 17762160; 17906618; 18042622; 18076569; 18247371; 18326489; 18350355; 18408012; 18460467; 18480410; 18487454; 18490454; 18598350; 18676680; 19001851; 19050041; 19170196; 19343042; 19363486; 19514266; 19514267; 19514268; 19615060; 19625176; 19692168; 19693690; 19700222; 19718565; 19764350; 19822667; 19913121; 19953087; 19960242; 20013135; 20133653; 20213743; 20234188; 20345761; 20354813; 20357208; 20360068; 20379614; 20453000; 20491486; 20516069; 20628086; 20651683; 20673369; 20720012; 20826806; 21044075; 21139048; 21145489; 21163940; 21209322; 21220307; 21289309; 21335063; 21415596; 21435449; 21465480; 21482751; 21600237; 21671254; 21701498; 21712386; 21741478; 21799006; 21825040; 21832049; 21844361; 21890473; 21900206; 21922195; 21924349; 21963094; 21987572; 22078880; 22223639; 22505724; 22547140; 22654103; 22696682; 22753194; 22768111; 22778260; 22829587; 22833568; 22874667; 22899714; 22939629; 22964075; 22990118; 23206597; 23332172; 23362255; 23377270; 23401660; 23455922; 23543736; 23602568; 23728742; 23941877; 24085300; 24091658; 24135281; 24235147 cyclin-dependent kinase 5 HGNC:1774 HPRD:00449 MIM:123831 CDK5 Bin Zhao, Yue Liu, Oliver He CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 WEB: http://www.ncbi.nlm.nih.gov/gene CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1026 6p21.2 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000079 (EC: TAS, PMID: 8242751); GO_0000082 (EC: IDA, PMID: 10208428); GO_0000082 (EC: TAS); GO_0000086 (EC: IMP, PMID: 17553787); GO_0000278 (EC: TAS); GO_0000307 (EC: IDA, PMID: 17420273); GO_0004861 (EC: TAS, PMID: 7958916); GO_0005515 (EC: IPI, PMID: 15232106); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005829 (EC: TAS); GO_0006468 (EC: IDA, PMID: 9106657); GO_0006974 (EC: IMP); GO_0006977 (EC: IDA, PMID: 15149599); GO_0006977 (EC: TAS); GO_0007050 (EC: IDA, PMID: 15149599); GO_0007050 (EC: IMP, PMID: 17553787); GO_0007173 (EC: TAS); GO_0007265 (EC: IEP, PMID: 9054499); GO_0008285 (EC: IDA, PMID: 10208428); GO_0008285 (EC: IMP, PMID: 17553787); GO_0008543 (EC: TAS); GO_0009411 (EC: IEA); GO_0009636 (EC: IEA); GO_0010243 (EC: IEA); GO_0010629 (EC: IEA); GO_0019912 (EC: IDA, PMID: 9106657); GO_0030308 (EC: IDA, PMID: 10208428); GO_0030332 (EC: IEA); GO_0030890 (EC: IEA); GO_0031100 (EC: IEA); GO_0031668 (EC: IMP, PMID: 17553787); GO_0032403 (EC: IEA); GO_0033158 (EC: IEA); GO_0038095 (EC: TAS); GO_0042326 (EC: IDA, PMID: 10208428); GO_0042493 (EC: IEA); GO_0042771 (EC: IEA); GO_0043066 (EC: IEA); GO_0043068 (EC: IEA); GO_0043231 (EC: IDA); GO_0045087 (EC: TAS); GO_0045736 (EC: IEA); GO_0045860 (EC: IDA, PMID: 9106657); GO_0046685 (EC: IEA); GO_0046872 (EC: IEA); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0048146 (EC: IMP, PMID: 17420273); GO_0051412 (EC: IEA); GO_0055093 (EC: IEA); GO_0070557 (EC: IDA, PMID: 18794347); GO_0071479 (EC: IMP); GO_0071850 (EC: IEA); GO_0090398 (EC: IMP, PMID: 15149599); GO_0090400 (EC: TAS); GO_0097193 (EC: TAS, PMID: 9660939); GO_2000278 (EC: IEA); GO_2000379 (EC: IMP) PMID: 7478582; 7478594; 7655464; 7698009; 7753561; 7780738; 7911228; 7958916; 8084608; 8101826; 8125163; 8242751; 8242752; 8259214; 8560263; 8622677; 8641969; 8647134; 8657154; 8662825; 8700517; 8756624; 8807325; 8861913; 8861969; 8891332; 8999999; 9054499; 9106657; 9178907; 9190208; 9218599; 9372966; 9380407; 9396813; 9464540; 9465025; 9467962; 9472014; 9515786; 9545252; 9546435; 9632134; 9658399; 9660939; 9705499; 9716181; 9716736; 9736735; 9798959; 9799125; 9811456; 9822382; 9837900; 9840927; 9840943; 9858585; 9858587; 10022118; 10022926; 10208428; 10323868; 10337545; 10455148; 10486249; 10529385; 10581175; 10679299; 10692450; 10698951; 10710306; 10753973; 10764767; 10828884; 10837373; 10848585; 10858286; 10873631; 10874474; 10878006; 10891505; 10912791; 10918595; 10973963; 11022036; 11076863; 11084299; 11132966; 11175348; 11179504; 11231585; 11254741; 11255227; 11302688; 11313979; 11343236; 11350925; 11389691; 11463845; 11477082; 11498536; 11559705; 11642719; 11684722; 11695244; 11700040; 11733969; 11741909; 11748297; 11751405; 11751903; 11756412; 11762751; 11781193; 11809712; 11815410; 11842244; 11860939; 11872638; 11877274; 11877298; 11877436; 11882322; 11893252; 11896572; 11908736; 11911463; 11931757; 11943869; 11953864; 11956602; 11968052; 11989975; 12015083; 12025230; 12036888; 12046058; 12052868; 12054510; 12054572; 12054658; 12055678; 12058028; 12111504; 12123335; 12138103; 12145325; 12151346; 12151347; 12151395; 12168821; 12204872; 12205674; 12354776; 12359245; 12361598; 12370305; 12379120; 12383116; 12384701; 12388558; 12392301; 12393707; 12396717; 12400017; 12407107; 12412576; 12417334; 12417722; 12429910; 12431783; 12431987; 12434183; 12441075; 12457968; 12459877; 12474524; 12477932; 12485998; 12513833; 12517948; 12519780; 12522211; 12527941; 12531694; 12545156; 12573582; 12599217; 12612054; 12642873; 12644083; 12651158; 12665570; 12665584; 12680256; 12681289; 12690110; 12698196; 12699883; 12705898; 12706118; 12716906; 12727210; 12727815; 12748190; 12771291; 12781424; 12782595; 12800980; 12809883; 12810668; 12820963; 12825853; 12839982; 12841870; 12847090; 12853982; 12855666; 12867429; 12884030; 12885947; 12890637; 12897156; 12930830; 12930846; 12931225; 12936910; 12947099; 12949733; 12963997; 12964161; 12970742; 13678583; 14504476; 14572899; 14574404; 14580260; 14592451; 14597617; 14607331; 14607337; 14628083; 14633995; 14637149; 14642618; 14647439; 14677632; 14702288; 14712207; 14715257; 14719078; 14726710; 14738489; 14744793; 14751560; 14759525; 14761977; 14762439; 14764039; 14981901; 15001356; 15003515; 15014036; 15016552; 15024057; 15033443; 15036662; 15059516; 15060836; 15069711; 15081425; 15082782; 15084259; 15094066; 15107488; 15111320; 15122333; 15142382; 15149599; 15161699; 15169570; 15171713; 15173090; 15179054; 15181148; 15184045; 15184659; 15190207; 15201954; 15201979; 15226418; 15232106; 15240512; 15251435; 15286705; 15291355; 15297421; 15302882; 15309711; 15317660; 15321712; 15340083; 15342418; 15347670; 15367606; 15371422; 15371446; 15378017; 15386430; 15389598; 15456784; 15474507; 15475071; 15489334; 15489336; 15492264; 15497017; 15509808; 15510615; 15528212; 15546622; 15555546; 15557281; 15574338; 15576034; 15580267; 15582998; 15592362; 15598783; 15606307; 15609309; 15616584; 15623356; 15645120; 15647383; 15660129; 15664193; 15665589; 15665816; 15671036; 15674334; 15674341; 15690394; 15694358; 15694838; 15695403; 15708847; 15709169; 15710329; 15716956; 15735102; 15736438; 15738655; 15743033; 15743834; 15746092; 15750619; 15752352; 15753078; 15756520; 15763542; 15764647; 15765097; 15767448; 15776189; 15780936; 15780937; 15798220; 15807891; 15817070; 15819981; 15839202; 15840769; 15856024; 15866118; 15878916; 15880444; 15880942; 15890360; 15893728; 15905168; 15936816; 15942645; 15944261; 15960923; 15964852; 15964998; 15965232; 15972853; 15975933; 15989967; 16009130; 16012716; 16014176; 16054204; 16078010; 16080520; 16081043; 16082198; 16082224; 16091736; 16111738; 16122475; 16135801; 16142303; 16142340; 16149052; 16150942; 16169070; 16182613; 16189514; 16191374; 16199872; 16200730; 16214366; 16226712; 16243918; 16248979; 16254341; 16256947; 16262255; 16276353; 16280359; 16283431; 16287849; 16288006; 16289646; 16343435; 16344056; 16344560; 16364249; 16381901; 16394138; 16432835; 16434701; 16464125; 16474839; 16479163; 16480585; 16507767; 16510448; 16514663; 16533812; 16551699; 16554660; 16580634; 16581770; 16616141; 16678112; 16705171; 16712793; 16718778; 16723699; 16735508; 16765349; 16775840; 16777994; 16782892; 16803887; 16804724; 16804901; 16818630; 16831599; 16835890; 16837471; 16867219; 16951143; 16952553; 16953367; 16964243; 16982699; 17008550; 17014852; 17016640; 17050675; 17054950; 17055654; 17059853; 17062672; 17072949; 17074759; 17079232; 17079872; 17080297; 17080554; 17108107; 17109628; 17115032; 17130157; 17158927; 17172426; 17172832; 17188136; 17203174; 17214516; 17239344; 17273559; 17283049; 17284535; 17286201; 17292858; 17293600; 17293864; 17294043; 17300726; 17303651; 17317670; 17325029; 17337084; 17339230; 17351341; 17371838; 17373842; 17388661; 17409409; 17420273; 17431791; 17438369; 17443496; 17448597; 17460193; 17460194; 17465503; 17477906; 17498252; 17502456; 17513615; 17517622; 17536310; 17553787; 17556661; 17560543; 17585201; 17588519; 17592292; 17595776; 17606716; 17611661; 17616661; 17617120; 17619016; 17627285; 17634558; 17638911; 17641414; 17656367; 17662641; 17671089; 17671689; 17671727; 17679094; 17682292; 17684142; 17686574; 17692879; 17700068; 17721438; 17804869; 17855660; 17873065; 17885207; 17894409; 17911387; 17920036; 17925548; 17937105; 17941827; 17952758; 17972508; 18004740; 18024214; 18025091; 18035504; 18046503; 18049450; 18057010; 18067855; 18071305; 18086887; 18097575; 18156402; 18162471; 18162533; 18166158; 18172194; 18174230; 18174243; 18181833; 18202757; 18203777; 18205772; 18212054; 18215742; 18226366; 18230337; 18243530; 18251939; 18263614; 18278446; 18281511; 18281541; 18292944; 18298387; 18316600; 18334933; 18339845; 18348176; 18353898; 18358634; 18361427; 18374497; 18385383; 18385759; 18386236; 18400748; 18413741; 18427550; 18441278; 18451802; 18456456; 18458079; 18459109; 18463164; 18498065; 18507837; 18508827; 18509005; 18546941; 18559599; 18562088; 18563330; 18583941; 18593937; 18619950; 18632985; 18644983; 18655775; 18664350; 18694622; 18698027; 18703516; 18710616; 18713757; 18719376; 18765563; 18766473; 18782865; 18788572; 18790797; 18791688; 18794347; 18794348; 18798266; 18806827; 18818310; 18823025; 18829543; 18842998; 18850004; 18850315; 18852884; 18923142; 18941111; 18948188; 18949380; 18950845; 18979138; 18981726; 19001415; 19002614; 19033664; 19041685; 19058005; 19064572; 19091404; 19096232; 19102934; 19106607; 19122196; 19124506; 19125693; 19129183; 19134409; 19141585; 19159630; 19161984; 19176223; 19176530; 19177004; 19211566; 19211842; 19221506; 19223555; 19224585; 19237173; 19243472; 19249676; 19258477; 19262578; 19263441; 19269967; 19273588; 19275888; 19276188; 19276356; 19305381; 19321391; 19322021; 19322654; 19329556; 19330811; 19332548; 19339270; 19356250; 19364816; 19367277; 19383287; 19384944; 19407849; 19409758; 19435914; 19452712; 19453261; 19458054; 19465901; 19465904; 19481339; 19487575; 19491257; 19491398; 19502805; 19505915; 19513497; 19528229; 19536092; 19536131; 19538940; 19541625; 19550124; 19557639; 19560419; 19572978; 19578553; 19581932; 19609363; 19626602; 19628749; 19629483; 19635457; 19638413; 19643983; 19657064; 19657726; 19664338; 19667069; 19668373; 19670700; 19672706; 19686092; 19686743; 19692168; 19693773; 19704162; 19713748; 19723065; 19723093; 19723627; 19730150; 19732026; 19738611; 19750108; 19773351; 19789190; 19795398; 19798054; 19802676; 19818775; 19819988; 19820361; 19822666; 19840446; 19855935; 19860623; 19895794; 19910837; 19913121; 19914103; 19921577; 19923826; 19931389; 19935879; 19950226; 19955391; 19956635; 19956888; 19958256; 20006705; 20012529; 20018861; 20025780; 20039273; 20054616; 20062013; 20062063; 20067556; 20071335; 20079711; 20084294; 20086099; 20101223; 20102411; 20112071; 20126416; 20127253; 20139077; 20144199; 20154723; 20160708; 20164022; 20169278; 20179200; 20190802; 20190813; 20190815; 20193371; 20203690; 20204299; 20204303; 20211058; 20219912; 20301197; 20302655; 20303835; 20308078; 20331843; 20347598; 20349127; 20350217; 20351180; 20357201; 20363991; 20369488; 20370687; 20383190; 20388787; 20419447; 20428774; 20433229; 20444901; 20452353; 20453000; 20458559; 20466633; 20495378; 20504375; 20508865; 20510020; 20510146; 20524403; 20544840; 20583115; 20587660; 20598695; 20600642; 20605778; 20606006; 20622899; 20628086; 20644561; 20668328; 20701798; 20702488; 20732856; 20803550; 20813048; 20814747; 20818156; 20844987; 20858736; 20878079; 20890119; 20954283; 20955243; 20966541; 20979563; 21040707; 21046779; 21048031; 21054888; 21076409; 21087528; 21088000; 21098705; 21115898; 21124069; 21127431; 21139048; 21148311; 21165952; 21242961; 21245169; 21262772; 21288367; 21292770; 21308745; 21311948; 21325273; 21325288; 21325480; 21336720; 21342417; 21358637; 21368573; 21383005; 21402054; 21415438; 21415862; 21417953; 21419318; 21430453; 21437722; 21439247; 21443127; 21460037; 21475302; 21478095; 21511729; 21515331; 21526487; 21532626; 21546904; 21552210; 21554918; 21559393; 21561680; 21565979; 21567397; 21575583; 21608063; 21616632; 21628527; 21637851; 21637966; 21642427; 21652709; 21666704; 21677879; 21685936; 21704589; 21709715; 21725088; 21726628; 21729169; 21768776; 21769863; 21780161; 21791360; 21804532; 21820300; 21832049; 21858171; 21870644; 21875573; 21877955; 21887277; 21890473; 21900206; 21903579; 21906983; 21907315; 21918011; 21933447; 21933903; 21938741; 21956786; 21963094; 21976111; 21988832; 22001409; 22002313; 22009857; 22032898; 22101335; 22110135; 22117196; 22135025; 22147197; 22160829; 22172947; 22173494; 22190353; 22199295; 22206000; 22211246; 22214381; 22216119; 22217266; 22227369; 22244827; 22249270; 22262409; 22266309; 22277651; 22291954; 22296117; 22311974; 22320961; 22321971; 22371483; 22383522; 22392074; 22401965; 22427654; 22428663; 22446964; 22449259; 22469187; 22490020; 22503977; 22510560; 22511267; 22511763; 22514271; 22521293; 22547059; 22547681; 22555846; 22615960; 22634755; 22650359; 22662213; 22673765; 22675167; 22683204; 22684370; 22698403; 22711822; 22713239; 22732402; 22735451; 22751124; 22771799; 22797886; 22814028; 22814742; 22820403; 22828875; 22858377; 22859066; 22869584; 22956625; 22964432; 22980580; 22988851; 22995373; 22997714; 23000965; 23007394; 23007395; 23013131; 23026136; 23034899; 23037503; 23066038; 23085750; 23085987; 23128396; 23133524; 23146670; 23153928; 23158659; 23159636; 23160381; 23167335; 23167427; 23169665; 23178572; 23184467; 23187802; 23208500; 23210340; 23211592; 23213251; 23215027; 23219618; 23224600; 23231583; 23236067; 23238566; 23253087; 23255119; 23261596; 23261678; 23271730; 23275116; 23292332; 23306062; 23306186; 23318451; 23324739; 23329847; 23333058; 23349794; 23349842; 23359201; 23375502; 23376845; 23382584; 23383273; 23388456; 23399735; 23449391; 23455922; 23457546; 23458879; 23463857; 23536437; 23555284; 23577194; 23582783; 23590292; 23601845; 23602568; 23603558; 23618860; 23639631; 23645206; 23652278; 23665236; 23684928; 23715767; 23737759; 23745637; 23759594; 23780339; 23807750; 23832541; 23832542; 23856463; 23928864; 23949224; 24027428; 24074410; 24076166; 24082141; 24119401; 24123000; 24134839; 24217248; 24225749; 24244542; 24277930; 24291038; 24379070 cyclin-dependent kinase inhibitor 1A (p21, Cip1) Ensembl:ENSG00000124762 HGNC:1784 HPRD:00298 MIM:116899 Vega:OTTHUMG00000014603 CDKN1A Bin Zhao, Yue Liu, Oliver He ARF CDK4I CDKN2 CMM2 INK4 INK4A MLM MTS-1 MTS1 P14 P14ARF P16 P16-INK4A P16INK4 P16INK4A P19 P19ARF TP16 WEB: http://www.ncbi.nlm.nih.gov/gene CDKN2A cyclin-dependent kinase inhibitor 2A 1029 9p21 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000075 (EC: IMP, PMID: 16243918); GO_0000082 (EC: IDA, PMID: 10208428); GO_0000209 (EC: IDA, PMID: 18305112); GO_0000278 (EC: TAS); GO_0001953 (EC: IMP, PMID: 10205165); GO_0002039 (EC: IPI, PMID: 9529249); GO_0003677 (EC: IEA); GO_0004861 (EC: IDA, PMID: 8259215); GO_0005515 (EC: IPI, PMID: 11278317); GO_0005634 (EC: IDA, PMID: 16243918); GO_0005654 (EC: IDA, PMID: 10360174); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA); GO_0005737 (EC: IDA, PMID: 16243918); GO_0005739 (EC: IEA); GO_0005829 (EC: TAS); GO_0006351 (EC: IEA); GO_0006364 (EC: IEA); GO_0006469 (EC: IMP, PMID: 15582998); GO_0006919 (EC: IMP, PMID: 12082630); GO_0007050 (EC: IDA, PMID: 15149599); GO_0007050 (EC: IMP, PMID: 16243918); GO_0007265 (EC: IEP, PMID: 9054499); GO_0008134 (EC: IPI, PMID: 19057511); GO_0008285 (EC: IDA, PMID: 15149599); GO_0008285 (EC: IMP, PMID: 16243918); GO_0008637 (EC: IMP, PMID: 12082630); GO_0010389 (EC: IMP, PMID: 15582998); GO_0016604 (EC: IDA, Qualifier: colocalizes_with, PMID: 10360174); GO_0019901 (EC: IPI, PMID: 8259215); GO_0030308 (EC: IDA, PMID: 10208428); GO_0030889 (EC: ISS); GO_0031647 (EC: ISS); GO_0031648 (EC: IDA, PMID: 9529249); GO_0032088 (EC: IDA, PMID: 10353611); GO_0033088 (EC: ISS); GO_0033235 (EC: IMP, PMID: 19057511); GO_0034393 (EC: ISS); GO_0035985 (EC: IDA, PMID: 16901784); GO_0035986 (EC: IMP, PMID: 16901784); GO_0042326 (EC: IDA, PMID: 10208428); GO_0043234 (EC: IDA, PMID: 9529249); GO_0043517 (EC: IDA, PMID: 9529249); GO_0044822 (EC: IDA); GO_0045736 (EC: IDA, PMID: 8259215); GO_0045892 (EC: IMP, PMID: 16901784); GO_0045893 (EC: IDA, PMID: 17569660); GO_0045944 (EC: IDA, PMID: 17569660); GO_0046825 (EC: IMP, PMID: 10360174); GO_0048103 (EC: ISS); GO_0050821 (EC: IDA, PMID: 10360174); GO_0051059 (EC: IDA, PMID: 10353611); GO_0051444 (EC: ISS); GO_0055105 (EC: ISS); GO_0070534 (EC: IDA, PMID: 18305112); GO_0071158 (EC: IDA, PMID: 9529249); GO_0090398 (EC: IMP, PMID: 14966292); GO_0090399 (EC: IMP, PMID: 14720514); GO_0097371 (EC: IPI, PMID: 9529249); GO_1902510 (EC: IMP, PMID: 12082630); GO_2000111 (EC: ISS); GO_2000774 (EC: IMP, PMID: 16901784) PMID: 7541708; 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21738007; 21743959; 21747645; 21757289; 21757290; 21777578; 21778791; 21797124; 21799651; 21799732; 21820152; 21830402; 21836494; 21840041; 21843312; 21846774; 21847682; 21849808; 21857254; 21880712; 21893440; 21895773; 21896275; 21912429; 21915115; 21916701; 21920947; 21942715; 21956468; 21968977; 21971053; 21979598; 21983787; 21987080; 21988832; 21990227; 22011452; 22020331; 22025288; 22027748; 22046342; 22047081; 22049925; 22052559; 22067611; 22072122; 22080060; 22080569; 22082146; 22083977; 22095233; 22096510; 22106032; 22119613; 22120712; 22126203; 22134481; 22134685; 22139419; 22154617; 22157933; 22169643; 22174919; 22178423; 22190034; 22192146; 22203921; 22206000; 22212460; 22217548; 22218684; 22221586; 22230750; 22248274; 22261253; 22285491; 22285991; 22287653; 22288845; 22290439; 22292911; 22299207; 22301498; 22310292; 22344043; 22354873; 22354970; 22368299; 22371043; 22378045; 22383580; 22395505; 22395603; 22398292; 22422578; 22429295; 22440936; 22449151; 22450744; 22460425; 22467867; 22483988; 22490850; 22502664; 22509111; 22521293; 22524808; 22534780; 22549447; 22558275; 22561347; 22565003; 22574968; 22576576; 22578565; 22590809; 22590819; 22611935; 22612594; 22619049; 22636603; 22652652; 22667340; 22675168; 22684221; 22705216; 22706276; 22707614; 22724384; 22733129; 22735904; 22738669; 22739067; 22751126; 22772724; 22820083; 22821242; 22841127; 22843877; 22860085; 22860097; 22863883; 22883455; 22889820; 22910419; 22911296; 22923468; 22925370; 22960768; 22966418; 22967446; 22991302; 22994152; 22998186; 23016962; 23023333; 23028987; 23032699; 23034180; 23034738; 23045280; 23065465; 23073540; 23075891; 23086695; 23104006; 23111194; 23128528; 23145162; 23154831; 23158280; 23159155; 23175521; 23178718; 23199516; 23209189; 23218882; 23225431; 23244153; 23259295; 23270897; 23275143; 23277542; 23279822; 23289480; 23301219; 23303449; 23308265; 23310950; 23311322; 23311918; 23315372; 23315417; 23326336; 23343716; 23361049; 23370473; 23371019; 23372805; 23379189; 23384855; 23392000; 23416275; 23423975; 23443045; 23444219; 23444377; 23449888; 23449974; 23455154; 23455922; 23459718; 23462994; 23470568; 23474228; 23497965; 23504555; 23504914; 23508829; 23535729; 23553486; 23558569; 23561647; 23565280; 23577085; 23585871; 23593412; 23600700; 23602568; 23635817; 23640413; 23645774; 23673926; 23686316; 23686572; 23695891; 23703248; 23711066; 23712779; 23721148; 23724131; 23727582; 23736021; 23747016; 23748155; 23771122; 23777425; 23808580; 23818364; 23832541; 23851489; 23861858; 23878395; 23894465; 23900870; 23900873; 23913416; 23916291; 23918540; 23923073; 23945395; 23948183; 23949224; 23996088; 24012816; 24037287; 24046371; 24067370; 24067458; 24081504; 24104554; 24163379; 24344027; 24344258; 24522534 cyclin-dependent kinase inhibitor 2A Ensembl:ENSG00000147889 HGNC:1787 HPRD:02542 MIM:600160 Vega:OTTHUMG00000019686 CDKN2A Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene CDO1 cysteine dioxygenase type 1 1036 5q23.2 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0000096 (EC: TAS); GO_0000097 (EC: TAS, PMID: 12110289); GO_0000098 (EC: TAS); GO_0005829 (EC: TAS, PMID: 12110289); GO_0006534 (EC: TAS, PMID: 12110289); GO_0006954 (EC: TAS, PMID: 12110289); GO_0007595 (EC: IEA); GO_0008198 (EC: IEA); GO_0017172 (EC: ISS); GO_0017172 (EC: TAS); GO_0019448 (EC: IEA); GO_0033762 (EC: IEA); GO_0034641 (EC: TAS); GO_0042412 (EC: IEA); GO_0042412 (EC: TAS, PMID: 12871209); GO_0043200 (EC: IEA); GO_0044281 (EC: TAS); GO_0045471 (EC: IEA); GO_0051384 (EC: IEA); GO_0051591 (EC: IEA); GO_0055114 (EC: TAS, PMID: 12110289) PMID: 7524679; 8835096; 9497919; 11101006; 12110289; 12477932; 12871209; 15302935; 15489334; 17207965; 17327371; 17353931; 18033314; 18976975; 19199799; 20515469; 21139048; 21988832; 22011669; 23028699; 23630167 cysteine dioxygenase type 1 CDO1 Bin Zhao, Yue Liu, Oliver He BPIFF HDLCQ10 WEB: http://www.ncbi.nlm.nih.gov/gene CETP cholesteryl ester transfer protein, plasma 1071 16q21 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0005319 (EC: IDA, PMID: 2833496); GO_0005548 (EC: IDA, PMID: 2833496); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 3104518); GO_0006641 (EC: IDA, PMID: 2833496); GO_0006869 (EC: IDA, PMID: 3818596); GO_0006898 (EC: TAS); GO_0008203 (EC: IDA, PMID: 2833496); GO_0008203 (EC: IMP, PMID: 2586614); GO_0008289 (EC: IDA, PMID: 3818596); GO_0010745 (EC: IC, PMID: 16670775); GO_0010874 (EC: IMP, PMID: 16670775); GO_0015485 (EC: IDA, PMID: 2833496); GO_0015914 (EC: IDA, PMID: 2833496); GO_0017127 (EC: IDA, PMID: 2833496); GO_0017129 (EC: IDA, PMID: 2833496); GO_0030301 (EC: IDA, PMID: 2833496); GO_0031210 (EC: IDA, PMID: 2833496); GO_0031982 (EC: IDA, PMID: 2833496); GO_0034364 (EC: IDA, PMID: 3104518); GO_0034372 (EC: IDA, PMID: 2833496); GO_0034374 (EC: IDA, PMID: 2833496); GO_0034375 (EC: IMP, PMID: 2586614); GO_0042157 (EC: TAS); GO_0042632 (EC: IMP, PMID: 2586614); GO_0043691 (EC: IC, PMID: 7583561); GO_0044281 (EC: TAS); GO_0046470 (EC: IDA, PMID: 2833496); GO_0055088 (EC: IDA, PMID: 3818596); GO_0055091 (EC: IDA, PMID: 2833496); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070328 (EC: IDA, PMID: 2833496) PMID: 1999438; 2215607; 2334701; 2390095; 2586614; 2833496; 3104518; 3446583; 3600759; 3818596; 7583561; 7989465; 8132678; 8408659; 8494888; 8943225; 9305883; 9332354; 9374130; 9712344; 10391209; 11056092; 11096142; 11284423; 11322655; 11341749; 11359462; 11369008; 11398140; 11454014; 11533368; 11575217; 11689220; 11714857; 11730826; 11804197; 11810297; 11872695; 11882335; 11887180; 11888509; 11888533; 11903340; 11915346; 11952809; 11956670; 11996962; 12019635; 12033532; 12037734; 12048136; 12055319; 12070157; 12082592; 12091484; 12104085; 12116231; 12117730; 12164095; 12174215; 12401886; 12409629; 12446192; 12477932; 12482565; 12499392; 12514935; 12518020; 12519368; 12519369; 12544508; 12579494; 12588754; 12601526; 12639975; 12663600; 12669678; 12700892; 12730302; 12771320; 12771549; 12773093; 12791674; 12798569; 12818401; 12818414; 12820950; 12840632; 12871320; 12907677; 12919138; 12951364; 12966036; 14531818; 14559957; 14563342; 14583798; 14660992; 14669156; 14679166; 14687732; 14732872; 14967821; 14998629; 15036597; 15039125; 15053158; 15076187; 15085362; 15098490; 15099350; 15102891; 15138631; 15228446; 15256516; 15339254; 15377415; 15382463; 15450208; 15489334; 15585206; 15589073; 15608561; 15655129; 15696473; 15766738; 15811250; 15840744; 15856070; 15859394; 15864114; 15882786; 15888337; 15896905; 15939053; 15952120; 15955471; 15979432; 15992403; 15996208; 16002074; 16005462; 16030523; 16038892; 16039291; 16049032; 16086925; 16096813; 16098387; 16123327; 16141008; 16159884; 16169070; 16189514; 16205020; 16248996; 16306202; 16306375; 16326978; 16332659; 16335952; 16343038; 16384616; 16420563; 16426594; 16430904; 16522905; 16542392; 16544732; 16553359; 16563399; 16623947; 16670775; 16674961; 16684835; 16763159; 16770077; 16797310; 16822236; 16829344; 16837242; 16855190; 16890925; 16946130; 16986521; 17053273; 17055779; 17097007; 17108362; 17157861; 17160943; 17190939; 17196207; 17237796; 17272756; 17275808; 17287950; 17293475; 17310124; 17311515; 17318300; 17335774; 17440012; 17463246; 17495597; 17503098; 17512305; 17512363; 17519358; 17522050; 17531380; 17555738; 17568242; 17568951; 17587762; 17587768; 17588582; 17615573; 17658505; 17666459; 17700364; 17709636; 17767699; 17785925; 17848121; 17852818; 17855807; 17931083; 17949364; 17970962; 17991668; 17991755; 18033754; 18034366; 18036514; 18056760; 18063597; 18064308; 18164013; 18178167; 18187430; 18193043; 18193044; 18221399; 18239576; 18243217; 18275964; 18279878; 18287799; 18289550; 18354102; 18369235; 18393253; 18454146; 18454345; 18468607; 18494281; 18503096; 18509195; 18513389; 18518852; 18549840; 18560005; 18562803; 18622260; 18636124; 18637884; 18660489; 18665040; 18667902; 18669886; 18676680; 18680734; 18728123; 18787507; 18804459; 18823627; 18835593; 18841571; 18849221; 18851690; 18926541; 18956684; 18957472; 18996102; 19018779; 19038839; 19038848; 19056069; 19056482; 19056867; 19060906; 19060910; 19060911; 19086575; 19099922; 19131637; 19131662; 19140312; 19147676; 19148283; 19155782; 19165812; 19168039; 19170196; 19184337; 19191759; 19193611; 19200546; 19217440; 19242900; 19260141; 19263529; 19273719; 19282272; 19282863; 19285487; 19299407; 19336370; 19341173; 19345354; 19359809; 19360375; 19364639; 19403283; 19417222; 19420105; 19424605; 19428034; 19444232; 19463799; 19471550; 19479237; 19489872; 19491422; 19558216; 19558660; 19564641; 19578796; 19625176; 19641010; 19642912; 19679263; 19689828; 19691831; 19692168; 19728844; 19729601; 19733717; 19764573; 19773416; 19784962; 19810818; 19815603; 19822408; 19850020; 19878569; 19913121; 19926784; 19936222; 19948972; 19948975; 19956635; 19956911; 20006332; 20026784; 20031538; 20031551; 20031564; 20031591; 20059631; 20065167; 20066028; 20068209; 20082485; 20138746; 20139978; 20160193; 20167577; 20195290; 20200605; 20228163; 20370913; 20385819; 20385826; 20394740; 20398902; 20400780; 20403997; 20413122; 20413969; 20421239; 20430392; 20431066; 20452482; 20458649; 20489166; 20494359; 20511482; 20536507; 20565774; 20578904; 20581105; 20602615; 20628086; 20634891; 20673868; 20679960; 20686565; 20691829; 20694148; 20714348; 20717043; 20799898; 20822508; 20835684; 20838585; 20855565; 20864672; 20937151; 21039385; 21062971; 21146168; 21185205; 21252145; 21347282; 21352420; 21354572; 21371711; 21376264; 21380728; 21386085; 21524747; 21591583; 21609439; 21665990; 21689002; 21765051; 21767357; 21816162; 21822774; 21892657; 21899732; 21909109; 21943158; 21982411; 21988832; 22003152; 22056562; 22073289; 22079329; 22122979; 22122993; 22143414; 22234866; 22265126; 22286219; 22339301; 22344176; 22399527; 22403620; 22414273; 22464147; 22464213; 22474067; 22556171; 22584245; 22623978; 22679067; 22729881; 22813404; 22850130; 22854712; 22904275; 22916037; 22928361; 22952570; 23039379; 23083790; 23118302; 23129316; 23157875; 23181436; 23189141; 23312786; 23351584; 23389097; 23455636; 23477743; 23505323; 23522788; 23555584; 23591416; 23620138; 23623643; 23656756; 23676183; 23678159; 23726366; 23758630; 23772784; 23891427; 23950155; 24023260; 24023261; 24078569; 24115030 cholesteryl ester transfer protein, plasma Ensembl:ENSG00000087237 HGNC:1869 HPRD:00325 MIM:118470 Vega:OTTHUMG00000133279 CETP Bin Zhao, Yue Liu, Oliver He HM1 M1 M1R WEB: http://www.ncbi.nlm.nih.gov/gene CHRM1 cholinergic receptor, muscarinic 1 1128 11q13 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0004435 (EC: TAS, PMID: 9614217); GO_0005886 (EC: TAS); GO_0005887 (EC: IEA); GO_0006464 (EC: TAS, PMID: 1411529); GO_0007165 (EC: TAS, PMID: 3443095); GO_0007186 (EC: TAS, PMID: 7925360); GO_0007205 (EC: TAS, PMID: 9603968); GO_0007207 (EC: TAS, PMID: 8139539); GO_0007213 (EC: TAS, PMID: 8139539); GO_0007274 (EC: IEA); GO_0007399 (EC: TAS, PMID: 2739737); GO_0008144 (EC: IEA); GO_0008283 (EC: TAS, PMID: 1905013); GO_0008284 (EC: TAS, PMID: 2739737); GO_0014069 (EC: IEA); GO_0016020 (EC: TAS, PMID: 7925360); GO_0016907 (EC: IEA); GO_0030054 (EC: IEA); GO_0030425 (EC: IEA); GO_0032279 (EC: IEA); GO_0040012 (EC: IEA); GO_0043270 (EC: IGI, PMID: 14657398); GO_0043679 (EC: IEA); GO_0045211 (EC: IEA); GO_0046541 (EC: IEA); GO_0050890 (EC: IEA); GO_0090316 (EC: IEA) PMID: 1411529; 1445347; 1905013; 2336407; 2674717; 2739737; 3037705; 3443095; 3697105; 7925360; 8063729; 8139539; 8190105; 8248499; 8508928; 8938448; 9303164; 9518684; 9603968; 9614217; 10333492; 10336173; 11306684; 11855742; 12049494; 12476323; 12477932; 12694403; 12707929; 12810581; 12851722; 14504414; 14657398; 15086532; 15280370; 15383745; 15452121; 15489334; 16318751; 16328454; 16336219; 16368694; 16406470; 16439611; 16754659; 16874522; 16877267; 16902941; 16931638; 17272726; 17373692; 17415969; 17462859; 17540859; 17655760; 18073210; 18240029; 18249005; 18272392; 18282687; 18317461; 18322150; 18385290; 18454168; 18577758; 18723515; 18790604; 19086053; 19156168; 19183167; 19404243; 19451648; 19753311; 19863190; 19874574; 19913121; 19927300; 20133736; 20146726; 20201926; 20237496; 20467438; 20602615; 20628086; 21203415; 21605442; 21685390; 22117071; 22146060; 22338582; 22391213; 22450048; 22571431; 22865467; 22990911; 23147108; 23423139; 23455440; 23460876; 23604140; 23678982 cholinergic receptor, muscarinic 1 Ensembl:ENSG00000168539 HGNC:1950 HPRD:00338 MIM:118510 Vega:OTTHUMG00000167765 CHRM1 Bin Zhao, Yue Liu, Oliver He BFNC EBN EBN1 NACHR NACHRA4 NACRA4 WEB: http://www.ncbi.nlm.nih.gov/gene CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1137 20q13.33 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0001508 (EC: ISS); GO_0001666 (EC: IDA, PMID: 12189247); GO_0004889 (EC: IDA, PMID: 8906617); GO_0004889 (EC: TAS); GO_0005886 (EC: ISS); GO_0005886 (EC: TAS); GO_0005892 (EC: IDA, PMID: 8906617); GO_0006281 (EC: IMP, PMID: 16332175); GO_0006811 (EC: NAS, PMID: 8906617); GO_0006816 (EC: ISS); GO_0006979 (EC: IMP, PMID: 16332175); GO_0007165 (EC: IDA, PMID: 8906617); GO_0007268 (EC: NAS, PMID: 7550350); GO_0007268 (EC: TAS); GO_0007271 (EC: ISS); GO_0007585 (EC: IEA); GO_0007626 (EC: IEA); GO_0009897 (EC: ISS); GO_0014059 (EC: ISS); GO_0015276 (EC: TAS); GO_0015464 (EC: IDA, PMID: 8906617); GO_0016020 (EC: ISS); GO_0016021 (EC: NAS, PMID: 8906617); GO_0019233 (EC: ISS); GO_0030054 (EC: IEA); GO_0030425 (EC: ISS); GO_0034220 (EC: TAS); GO_0035094 (EC: IDA, PMID: 12189247); GO_0035095 (EC: IMP, PMID: 17955458); GO_0035640 (EC: IEA); GO_0042113 (EC: ISS); GO_0042166 (EC: IC, PMID: 8906617); GO_0042391 (EC: ISS); GO_0043025 (EC: ISS); GO_0045211 (EC: IEA); GO_0050877 (EC: IMP, PMID: 17613539); GO_0050890 (EC: IMP, PMID: 14623738); GO_0051899 (EC: ISS); GO_0060080 (EC: ISS) PMID: 1492743; 1505988; 2351675; 7550350; 7647781; 7721089; 7806245; 8833159; 8889548; 8906617; 8987816; 9009220; 10563623; 11261808; 11352901; 11409698; 11771745; 11780052; 12121305; 12185808; 12189247; 12202488; 12214130; 12477932; 12556914; 12565129; 12663058; 12681012; 12781587; 12782394; 12887442; 12887446; 14623738; 15046869; 15154117; 15717291; 15790597; 15902904; 15944128; 16023355; 16091357; 16174636; 16183856; 16205844; 16238698; 16332175; 16344560; 16407231; 16456787; 16608406; 16636791; 16825297; 16869227; 17226798; 17373692; 17385675; 17488453; 17504247; 17559419; 17590520; 17613539; 17768273; 17948872; 17955458; 17977823; 17981562; 18042647; 18043764; 18226955; 18298895; 18534558; 18691652; 18762859; 18821565; 18937294; 18991851; 19016604; 19020039; 19058789; 19058950; 19059502; 19063970; 19101612; 19156168; 19259974; 19290018; 19300482; 19336370; 19352218; 19429020; 19482438; 19484724; 19498063; 19506906; 19577488; 19620239; 19628475; 19693267; 19698703; 19803686; 19874574; 19896235; 20189461; 20201926; 20231857; 20301348; 20331911; 20493238; 20584212; 20634891; 20649589; 20734064; 20736995; 20881005; 20943775; 21130611; 21203548; 21252231; 21321393; 21343288; 21396349; 21432576; 21445957; 21451042; 21500914; 21593077; 21683344; 21740768; 21753767; 21757735; 21821135; 21900206; 22008229; 22103306; 22118295; 22119468; 22253823; 22359659; 22373960; 22553201; 22722381; 22760121; 22873564; 22947540; 23000369; 23240931; 23349463; 23350800; 23429692; 23437071; 23553665; 23734673; 23843950; 24327142; 24385388 cholinergic receptor, nicotinic, alpha 4 (neuronal) Ensembl:ENSG00000101204 HGNC:1958 HPRD:00333 MIM:118504 Vega:OTTHUMG00000033080 CHRNA4 Bin Zhao, Yue Liu, Oliver He CHRNA7-2 NACHRA7 WEB: http://www.ncbi.nlm.nih.gov/gene CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 1139 15q14 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0000187 (EC: IDA, PMID: 10771023); GO_0001540 (EC: IPI, PMID: 10681545); GO_0001666 (EC: IDA, PMID: 12189247); GO_0001988 (EC: IEA); GO_0004889 (EC: IDA, PMID: 12508119); GO_0005737 (EC: IEA); GO_0005886 (EC: IDA, PMID: 12508119); GO_0005886 (EC: TAS); GO_0005892 (EC: IDA, PMID: 8906617); GO_0006811 (EC: NAS, PMID: 8906617); GO_0006816 (EC: IDA, PMID: 8145738); GO_0006816 (EC: IMP, PMID: 10771023); GO_0006874 (EC: IMP, PMID: 16280133); GO_0006897 (EC: IEA); GO_0007165 (EC: IDA, PMID: 8906617); GO_0007268 (EC: TAS); GO_0007271 (EC: IEA); GO_0007613 (EC: NAS, PMID: 10681545); GO_0008144 (EC: IEA); GO_0008179 (EC: IEA); GO_0008284 (EC: IMP, PMID: 16280133); GO_0008306 (EC: IEA); GO_0009897 (EC: IEA); GO_0014061 (EC: IEA); GO_0014069 (EC: IEA); GO_0015464 (EC: IDA, PMID: 8906617); GO_0015643 (EC: IDA, PMID: 12508119); GO_0016021 (EC: NAS, PMID: 8145738); GO_0016324 (EC: IEA); GO_0017081 (EC: IDA, PMID: 8145738); GO_0019228 (EC: IEA); GO_0019901 (EC: IEA); GO_0030054 (EC: IEA); GO_0030317 (EC: IEA); GO_0030424 (EC: IEA); GO_0030426 (EC: IEA); GO_0032094 (EC: IEA); GO_0032225 (EC: IEA); GO_0032279 (EC: IEA); GO_0032691 (EC: IEA); GO_0032715 (EC: IEA); GO_0032720 (EC: IDA, PMID: 12508119); GO_0032720 (EC: IMP, PMID: 12508119); GO_0035094 (EC: IDA, PMID: 12189247); GO_0035095 (EC: IEA); GO_0042110 (EC: IEA); GO_0042113 (EC: IEA); GO_0042166 (EC: IDA, PMID: 8145738); GO_0042416 (EC: IEA); GO_0042734 (EC: IEA); GO_0042803 (EC: IDA, PMID: 8145738); GO_0043025 (EC: IEA); GO_0043197 (EC: IEA); GO_0043198 (EC: IEA); GO_0045121 (EC: IEA); GO_0045211 (EC: IEA); GO_0045766 (EC: IMP, PMID: 12189247); GO_0048149 (EC: IEA); GO_0050728 (EC: IEA); GO_0050890 (EC: IMP, PMID: 16754836); GO_0050890 (EC: NAS, PMID: 10681545); GO_0051117 (EC: IEA); GO_0060112 (EC: IEA); GO_0097110 (EC: IEA) PMID: 7571003; 8145738; 8188270; 8889549; 8906617; 8996215; 9009220; 9193799; 9782083; 10206225; 10206240; 10336173; 10681545; 10771023; 11150893; 11278378; 11424985; 11455129; 11532536; 11771745; 11803512; 11803513; 11829490; 11840317; 11840567; 11891308; 11891309; 11905992; 12020960; 12049804; 12189247; 12193385; 12214130; 12391028; 12399955; 12431773; 12454998; 12470124; 12477932; 12508119; 12509811; 12549904; 12626641; 12663058; 12748066; 12781587; 12783266; 14569275; 14582144; 14729237; 15046869; 15100704; 15219869; 15226316; 15252450; 15292665; 15465084; 15494367; 15504725; 15531077; 15807899; 15857954; 15896732; 15927954; 16280133; 16307758; 16314871; 16344560; 16417613; 16461803; 16563701; 16754836; 16822928; 16837119; 17012261; 17012698; 17015027; 17113175; 17192639; 17192651; 17241116; 17286584; 17291692; 17335853; 17373692; 17493709; 17498763; 17504249; 17559419; 17573436; 17709503; 17884806; 17920082; 17978319; 17981562; 18057084; 18071042; 18072279; 18073210; 18078695; 18198266; 18302933; 18307030; 18385739; 18387948; 18393235; 18450646; 18471073; 18545269; 18667281; 18691158; 18696274; 18800618; 18854154; 19038445; 19040571; 19058789; 19059502; 19080531; 19086053; 19136953; 19156168; 19181484; 19259974; 19307444; 19351547; 19367581; 19433665; 19462340; 19506073; 19549780; 19587288; 19623583; 19630919; 19631623; 19666073; 19736351; 19808646; 19896235; 19944766; 20006992; 20231857; 20236110; 20309583; 20463630; 20506139; 20518839; 20584212; 20602615; 20660165; 20691427; 20708605; 20720594; 20728875; 20734064; 20736995; 20864676; 20927308; 21047781; 21051662; 21062106; 21073885; 21390272; 21510634; 21550667; 21610071; 21630219; 21718690; 21790533; 21840925; 21861625; 21969082; 21979958; 22009746; 22031302; 22040696; 22052086; 22084248; 22253823; 22270376; 22300029; 22300033; 22336089; 22342972; 22359659; 22420046; 22420048; 22423106; 22441542; 22483691; 22553201; 22556416; 22577141; 22588665; 22614008; 22775350; 22981153; 23022323; 23275563; 23324234; 23325242; 23431157; 23800261; 23802200; 23851693; 24089524; 24297903 cholinergic receptor, nicotinic, alpha 7 (neuronal) HGNC:1960 HPRD:00339 MIM:118511 CHRNA7 Bin Zhao, Yue Liu, Oliver He EFNL3 nAChRB2 WEB: http://www.ncbi.nlm.nih.gov/gene CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1141 RP11-61L14.4 1q21.3 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001508 (EC: IEA); GO_0001661 (EC: IEA); GO_0001666 (EC: IDA, PMID: 12189247); GO_0004889 (EC: IDA, PMID: 8906617); GO_0004889 (EC: TAS); GO_0005886 (EC: TAS); GO_0005892 (EC: IDA, PMID: 8906617); GO_0006811 (EC: NAS, PMID: 8906617); GO_0006816 (EC: ISS); GO_0006939 (EC: ISS); GO_0007165 (EC: IDA, PMID: 8906617); GO_0007268 (EC: TAS); GO_0007271 (EC: ISS); GO_0007601 (EC: ISS); GO_0007605 (EC: ISS); GO_0007612 (EC: IMP, PMID: 15964197); GO_0007613 (EC: IMP, PMID: 15964197); GO_0007626 (EC: ISS); GO_0008144 (EC: IEA); GO_0008306 (EC: ISS); GO_0008542 (EC: IMP, PMID: 15964197); GO_0009897 (EC: ISS); GO_0014059 (EC: ISS); GO_0015276 (EC: TAS); GO_0015464 (EC: IDA, PMID: 8906617); GO_0016021 (EC: NAS, PMID: 8906617); GO_0019233 (EC: ISS); GO_0021562 (EC: ISS); GO_0021631 (EC: ISS); GO_0021771 (EC: ISS); GO_0021952 (EC: ISS); GO_0030054 (EC: IEA); GO_0030890 (EC: ISS); GO_0032225 (EC: ISS); GO_0032226 (EC: IEA); GO_0033603 (EC: ISS); GO_0034220 (EC: TAS); GO_0035094 (EC: IDA, PMID: 12189247); GO_0035095 (EC: IMP, PMID: 17559419); GO_0035176 (EC: ISS); GO_0042053 (EC: ISS); GO_0042113 (EC: ISS); GO_0042166 (EC: IC, PMID: 8906617); GO_0042166 (EC: IMP, PMID: 15964197); GO_0042220 (EC: ISS); GO_0042320 (EC: ISS); GO_0045188 (EC: IEA); GO_0045211 (EC: IEA); GO_0045471 (EC: ISS); GO_0045759 (EC: ISS); GO_0048814 (EC: ISS); GO_0050877 (EC: IMP, PMID: 17900292); GO_0050890 (EC: IMP, PMID: 17559419); GO_0051291 (EC: IEA); GO_0051899 (EC: ISS); GO_0051963 (EC: ISS); GO_0060084 (EC: ISS) PMID: 1397297; 1505988; 2377478; 8906617; 8987816; 9009220; 9921897; 10441742; 10771020; 11054772; 11062464; 11104662; 11261808; 11771745; 11906688; 11952766; 12185808; 12189247; 12202488; 12214130; 12477932; 12663058; 12681012; 15026168; 15033200; 15046869; 15154117; 15489334; 15681842; 15944128; 15964197; 16023355; 16174636; 16183856; 16238698; 16314871; 16407231; 16636791; 16928859; 17192785; 17226798; 17373692; 17385675; 17559419; 17900292; 18043764; 18226955; 18242781; 18534558; 18534914; 18593715; 18762859; 18830724; 18991851; 19058950; 19059502; 19063970; 19086053; 19101612; 19156168; 19259974; 19279256; 19482438; 19620239; 19755656; 19874574; 20231857; 20301348; 20371741; 20413850; 20441771; 20534741; 20574532; 20603624; 20649589; 20677014; 20734064; 20736995; 20854418; 20880607; 20881005; 20923852; 20943775; 21252231; 21287502; 21396349; 21451042; 21536845; 21606948; 21757735; 22359659; 22553201; 23000369; 23429692; 23437071; 23734673 cholinergic receptor, nicotinic, beta 2 (neuronal) Ensembl:ENSG00000160716 HGNC:1962 HPRD:00335 MIM:118507 Vega:OTTHUMG00000037262 CHRNB2 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 1143 hCG_1731645 15q24 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0001508 (EC: IEA); GO_0004889 (EC: TAS, PMID: 11742001); GO_0005886 (EC: TAS); GO_0005887 (EC: IC, PMID: 11742001); GO_0005892 (EC: IDA, PMID: 8906617); GO_0005892 (EC: TAS, PMID: 11742001); GO_0006811 (EC: TAS, PMID: 8906617); GO_0006812 (EC: TAS, PMID: 11742001); GO_0006939 (EC: IEA); GO_0006940 (EC: IEA); GO_0007165 (EC: IDA, PMID: 8906617); GO_0007268 (EC: TAS); GO_0007271 (EC: TAS, PMID: 1330682); GO_0007626 (EC: IEA); GO_0015276 (EC: TAS); GO_0015464 (EC: IDA, PMID: 8906617); GO_0016021 (EC: NAS, PMID: 8906617); GO_0030054 (EC: IEA); GO_0034220 (EC: TAS); GO_0035095 (EC: IEA); GO_0045211 (EC: IEA); GO_0046928 (EC: NAS, PMID: 11742001); GO_0060084 (EC: IMP, PMID: 11450844) PMID: 1330682; 1505988; 1572664; 1689727; 1725184; 2004777; 7571003; 8906617; 8987816; 8996215; 9009220; 9193799; 9203638; 9655874; 9693793; 10336173; 11118490; 11181995; 11450844; 11606319; 11742001; 12150770; 12477932; 12663058; 12783266; 12912995; 15489334; 15742216; 16091357; 16826524; 17373692; 18163978; 18385738; 18385739; 18414406; 18519524; 18618000; 18759969; 18780872; 18996504; 19029397; 19059502; 19086053; 19156168; 19259974; 19429911; 19628475; 19628476; 19671882; 19696770; 19706762; 19859904; 20201926; 20418889; 20426799; 20485328; 20554942; 20584212; 20587604; 20631687; 20685379; 20734064; 20736995; 20808433; 20886544; 21107856; 21168125; 21228559; 21248747; 21343288; 21436384; 21486776; 21646606; 21658281; 21747048; 21917987; 22024278; 22042234; 22042774; 22101982; 22241830; 22336398; 22382680; 22382757; 22438940; 22459873; 22543065; 22945651; 22956269; 23029550; 23061658; 23143843; 23349463; 23458267; 23626818; 23691088; 23729684; 23844051; 23884938; 24085295 cholinergic receptor, nicotinic, beta 4 (neuronal) CHRNB4 Bin Zhao, Yue Liu, Oliver He APO-J APOJ CLI CLU1 CLU2 KUB1 NA1/NA2 SGP-2 SGP2 SP-40 TRPM-2 TRPM2 WEB: http://www.ncbi.nlm.nih.gov/gene CLU clusterin 1191 AAG4 8p21-p12 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0001836 (EC: IC, PMID: 16113678); GO_0002576 (EC: TAS); GO_0005515 (EC: IPI, PMID: 16113678); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 11123922); GO_0005634 (EC: IEA); GO_0005739 (EC: IDA, PMID: 16113678); GO_0005783 (EC: IEA); GO_0005829 (EC: IEA); GO_0006629 (EC: NAS, PMID: 2387851); GO_0006956 (EC: TAS, PMID: 1585460); GO_0006958 (EC: IEA); GO_0007596 (EC: TAS); GO_0009615 (EC: IEP, PMID: 16548883); GO_0016887 (EC: IDA, Qualifier: NOT, PMID: 11123922); GO_0030168 (EC: TAS); GO_0031012 (EC: IDA, Qualifier: colocalizes_with); GO_0031093 (EC: TAS); GO_0031625 (EC: IDA); GO_0031966 (EC: IEA); GO_0032436 (EC: IMP); GO_0032463 (EC: IMP, PMID: 16113678); GO_0034366 (EC: IDA, PMID: 16682745); GO_0042583 (EC: IEA); GO_0043065 (EC: IMP); GO_0043691 (EC: TAS, PMID: 16682745); GO_0045087 (EC: IEA); GO_0048471 (EC: IDA); GO_0050821 (EC: IDA, PMID: 11123922); GO_0051092 (EC: IMP); GO_0051787 (EC: IDA, PMID: 11123922); GO_0051787 (EC: IPI, PMID: 19996109); GO_0051788 (EC: IDA, PMID: 19996109); GO_0061077 (EC: IDA, PMID: 11123922); GO_0070062 (EC: IDA, PMID: 19056867); GO_0072562 (EC: IDA); GO_0097193 (EC: IDA); GO_1902230 (EC: IMP, PMID: 16113678); GO_2000060 (EC: IMP); GO_2001244 (EC: IMP) PMID: 1424805; 1491011; 1551440; 1585460; 1903064; 1924317; 1974459; 2185274; 2387851; 2454950; 2601725; 2721499; 2780565; 2780570; 3154963; 3167096; 7615015; 7626703; 7768901; 8181474; 8292612; 8314591; 8328966; 8345200; 8387101; 8555189; 8634259; 8752142; 8759347; 8843912; 8889548; 9228033; 9336835; 9537999; 10066740; 10219089; 10329371; 10694874; 11123922; 11186422; 11570883; 11714447; 11795992; 11813210; 11892985; 11904161; 11906815; 12082621; 12172907; 12176985; 12200037; 12393179; 12427144; 12429802; 12470829; 12477932; 12551933; 12679903; 12754519; 12824284; 12860995; 12867999; 12882985; 14618611; 14630798; 14702039; 14718574; 14760718; 15033782; 15133840; 15146195; 15158456; 15174051; 15247015; 15252304; 15304052; 15342556; 15389725; 15480429; 15489334; 15492264; 15499376; 15538973; 15591223; 15649646; 15689620; 15791650; 15809754; 15883054; 15925890; 15929184; 15955107; 16113678; 16179938; 16263699; 16331665; 16335952; 16421571; 16464517; 16490286; 16548883; 16675913; 16682745; 16709604; 16709934; 16740002; 16775601; 16806233; 16955214; 17043677; 17048076; 17056579; 17080454; 17148459; 17170699; 17203891; 17224269; 17260971; 17322305; 17407782; 17412999; 17420006; 17451556; 17512083; 17534116; 17535098; 17689225; 17855704; 17872975; 17974975; 18079682; 18082619; 18097679; 18239862; 18378577; 18458059; 18514801; 18542050; 18612545; 18624398; 18649357; 18709641; 18712185; 18714397; 18786636; 18806885; 18813793; 18842294; 19056867; 19118032; 19137541; 19165232; 19166932; 19177010; 19182256; 19220628; 19264665; 19289586; 19344414; 19353783; 19357365; 19391138; 19413638; 19446882; 19535339; 19542874; 19651157; 19664600; 19734902; 19734903; 19757199; 19793084; 19814590; 19878569; 19878770; 19878774; 19879420; 19879421; 19879422; 19879423; 19903339; 19903745; 19935703; 19940549; 19996109; 20000738; 20007348; 20009887; 20019877; 20028970; 20057494; 20058210; 20068069; 20096688; 20195357; 20209083; 20353268; 20360068; 20410100; 20460622; 20497247; 20534741; 20554627; 20570404; 20599866; 20603455; 20614220; 20674675; 20697030; 20738160; 20739100; 20842452; 20847305; 20850846; 20855565; 20873220; 20930273; 21042904; 21043527; 21059989; 21135756; 21163940; 21224044; 21240462; 21242307; 21280673; 21300948; 21347408; 21379329; 21397462; 21422520; 21447104; 21460841; 21460853; 21467232; 21467285; 21505792; 21508640; 21525168; 21527247; 21543606; 21567405; 21573492; 21627779; 21630085; 21633299; 21732348; 21761117; 21824521; 21892414; 21899841; 21900379; 21912625; 21953030; 21953454; 21980627; 21987172; 21988832; 21998749; 22012253; 22013110; 22015308; 22016805; 22068036; 22082661; 22122982; 22130675; 22145905; 22159129; 22166956; 22179788; 22232000; 22234156; 22236192; 22248099; 22258514; 22266332; 22268729; 22274961; 22296908; 22391565; 22402018; 22465014; 22506010; 22532874; 22539578; 22545109; 22569264; 22613415; 22617144; 22647452; 22689054; 22701550; 22795969; 22832520; 22863883; 22889670; 22896337; 22902018; 22906254; 22952074; 22975582; 22981431; 22990118; 23010347; 23051594; 23099883; 23174100; 23201481; 23208459; 23209684; 23276503; 23279642; 23411014; 23416242; 23455922; 23457489; 23538443; 23573206; 23589125; 23602568; 23621580; 23650005; 23673647; 23702390; 23769013; 23770713; 23786771; 23956692; 24073260 clusterin Alzpathway: AmyloidB-CLU dissociation; AmyloidB-CLU association_Brain; AmyloidB-CLU leading to Unknown transportation. Source: https://pubmed.ncbi.nlm.nih.gov/30872998/ Ensembl:ENSG00000120885 HGNC:2095 HPRD:01706 MIM:185430 Vega:OTTHUMG00000102114 CLU Bin Zhao, Yue Liu, Oliver He CD191 CKR-1 CKR1 CMKBR1 HM145 MIP1aR SCYAR1 WEB: http://www.ncbi.nlm.nih.gov/gene CCR1 chemokine (C-C motif) receptor 1 1230 3p21 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0002407 (EC: TAS, PMID: 16621978); GO_0004435 (EC: IDA, PMID: 10734056); GO_0004950 (EC: IDA, PMID: 10660125); GO_0005515 (EC: IPI, PMID: 15001559); GO_0005886 (EC: IDA, PMID: 10660125); GO_0005886 (EC: IMP, PMID: 15001559); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 7505609); GO_0006816 (EC: IDA, PMID: 10734056); GO_0006874 (EC: IDA, PMID: 10734056); GO_0006887 (EC: IDA, PMID: 10734056); GO_0006935 (EC: NAS, PMID: 15474493); GO_0006954 (EC: IEA); GO_0006955 (EC: IDA, PMID: 10734056); GO_0007155 (EC: TAS, PMID: 10910894); GO_0007166 (EC: TAS, PMID: 10770925); GO_0007187 (EC: TAS, PMID: 7505609); GO_0007204 (EC: IDA, PMID: 10734056); GO_0007267 (EC: IDA, PMID: 10734056); GO_0008152 (EC: IDA, PMID: 10734056); GO_0009611 (EC: TAS, PMID: 7505609); GO_0009897 (EC: IDA, PMID: 10706735); GO_0010629 (EC: IMP); GO_0016493 (EC: IDA, PMID: 10734056); GO_0019221 (EC: NAS, PMID: 15474493); GO_0019957 (EC: IPI, PMID: 10660125); GO_0030502 (EC: IMP); GO_0035717 (EC: IPI, PMID: 10660125); GO_0045672 (EC: IMP); GO_0051928 (EC: IDA, PMID: 15764707); GO_0070098 (EC: IDA); GO_0070374 (EC: IMP); GO_0071791 (EC: IPI, PMID: 10660125); GO_0090026 (EC: IDA, PMID: 18587271) PMID: 2834384; 7505609; 7545673; 7594543; 7679328; 7683036; 8011297; 8530354; 8626727; 8631787; 8699119; 9115216; 9143512; 9289016; 9346309; 9558365; 9886417; 10094132; 10202040; 10583963; 10660125; 10702689; 10706735; 10734056; 10770925; 10910894; 11085751; 11110672; 11116158; 11449371; 11470772; 11804551; 11832479; 11920567; 12070001; 12085329; 12270118; 12477932; 12651617; 12763925; 12794150; 14530297; 14595653; 14637022; 14674010; 15001559; 15039444; 15053339; 15103513; 15265234; 15337751; 15474493; 15489334; 15548526; 15764707; 15927850; 15950672; 16182378; 16226254; 16323127; 16621978; 16837468; 16969502; 17135764; 17192849; 17298994; 17336272; 17389578; 17464174; 17558413; 17914560; 18178867; 18240029; 18311140; 18559339; 18577758; 18587271; 18972130; 19017998; 19423540; 19553544; 19603542; 19664396; 19687291; 19693089; 19913121; 20015385; 20056178; 20086017; 20154287; 20190752; 20406964; 20429924; 20438785; 20628086; 20634891; 20802378; 20921899; 21148810; 21942940; 22007486; 22104149; 22650026; 22727097; 22829007; 22842622; 23054685; 23125416; 23217400; 23219091; 23233369; 23276697; 23291587; 24056371 chemokine (C-C motif) receptor 1 Ensembl:ENSG00000163823 HGNC:1602 HPRD:03101 MIM:601159 Vega:OTTHUMG00000133451 CCR1 Bin Zhao, Yue Liu, Oliver He CC-CKR-3 CD193 CKR3 CMKBR3 WEB: http://www.ncbi.nlm.nih.gov/gene CCR3 chemokine (C-C motif) receptor 3 1232 3p21.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0001938 (EC: IEA); GO_0004950 (EC: TAS, PMID: 10415069); GO_0005515 (EC: IPI); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 9302298); GO_0006935 (EC: IEA); GO_0006954 (EC: IEA); GO_0006968 (EC: TAS, PMID: 10713092); GO_0007155 (EC: TAS, PMID: 10201960); GO_0007188 (EC: TAS, PMID: 10201960); GO_0007204 (EC: TAS, PMID: 9302298); GO_0016032 (EC: IEA); GO_0016493 (EC: IEA); GO_0045766 (EC: IMP, PMID: 19525930); GO_0070098 (EC: TAS, PMID: 10415069) PMID: 7594543; 7622448; 8609214; 8631813; 8631926; 8642344; 8674119; 8676064; 8884276; 9005985; 9024664; 9143512; 9182688; 9252350; 9289016; 9302298; 9346309; 9359702; 9419219; 9573273; 9636210; 9653051; 9712872; 9736741; 9765440; 9789057; 10094132; 10201960; 10415069; 10488147; 10514402; 10527858; 10590105; 10642580; 10666479; 10713092; 10877489; 10900353; 10975800; 11001881; 11085751; 11110785; 11115360; 11120849; 11149986; 11196669; 11307756; 11396683; 11449371; 11832479; 11920572; 11991282; 11994538; 12023397; 12079287; 12149192; 12218106; 12393570; 12397598; 12477932; 12654630; 12794150; 12884299; 12902471; 14581140; 14647058; 14702039; 14733956; 15053339; 15086398; 15194768; 15219825; 15476879; 15489334; 15507393; 15580493; 15607028; 15807893; 15857508; 15992849; 16081847; 16174786; 16470129; 16631222; 16712896; 16904155; 16920975; 17041228; 17135764; 17146638; 17672867; 17703412; 17845580; 17983872; 18240029; 18244953; 18311140; 18379861; 18577758; 18636124; 18676680; 18805825; 18974840; 19017998; 19028820; 19131662; 19170196; 19218218; 19247692; 19258923; 19414538; 19423540; 19525930; 19526283; 19542083; 19553323; 19559392; 19625176; 19692168; 19693089; 19714638; 19731977; 20022477; 20056178; 20144207; 20190752; 20220260; 20237496; 20306659; 20364559; 20380698; 20406964; 20438785; 20503287; 20505746; 20603037; 20647273; 20659406; 20726325; 20734064; 20921899; 20923436; 21041734; 21077277; 21143381; 21280323; 21406396; 21660963; 21735070; 21917937; 22086059; 22217447; 22702503; 22829007; 22842622; 23017229; 23054685; 23183094; 23251661; 23291587; 23566847; 23636060; 23643185; 23702389; 23742077; 23955446 chemokine (C-C motif) receptor 3 Ensembl:ENSG00000183625 HGNC:1604 HPRD:03167 MIM:601268 Vega:OTTHUMG00000133484 CCR3 Bin Zhao, Yue Liu, Oliver He CC-CKR-4 CD194 CKR4 CMKBR4 ChemR13 HGCN:14099 K5-5 WEB: http://www.ncbi.nlm.nih.gov/gene CCR4 chemokine (C-C motif) receptor 4 1233 3p24 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0001764 (EC: IEA); GO_0002507 (EC: IEA); GO_0004950 (EC: TAS, PMID: 7642634); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 7642634); GO_0006935 (EC: IEA); GO_0006954 (EC: IEA); GO_0006955 (EC: IEA); GO_0007204 (EC: TAS, PMID: 7642634); GO_0009314 (EC: IEA); GO_0009617 (EC: IEA); GO_0009897 (EC: IEA); GO_0016493 (EC: IEA); GO_0043025 (EC: IEA); GO_0046677 (EC: IEA); GO_0050927 (EC: IEA); GO_0070098 (EC: TAS, PMID: 7642634) PMID: 7642634; 8573157; 8884276; 9169480; 9430724; 9743322; 9933589; 10036181; 10466728; 10754297; 11196669; 11861261; 12070001; 12270118; 12406880; 12429730; 12456591; 12477932; 12485447; 12778466; 14657875; 15187160; 15202833; 15328188; 15489334; 15569983; 15621800; 15857508; 15955100; 17071491; 17117949; 17546636; 18071306; 18240029; 18577758; 18782672; 19106589; 19239991; 19244125; 19261691; 19374191; 19423540; 19903885; 19913121; 19942450; 20148806; 20164417; 20190752; 20237293; 20237496; 20334681; 20364559; 20406964; 20412707; 20438785; 20628086; 20963786; 21443538; 21525208; 21739422; 22490506; 22842622; 23180648; 23644599; 23731651; 24127572 chemokine (C-C motif) receptor 4 HGNC:1605 HPRD:05324 MIM:604836 CCR4 Bin Zhao, Yue Liu, Oliver He CC-CKR-5 CCCKR5 CCR-5 CD195 CKR-5 CKR5 CMKBR5 IDDM22 WEB: http://www.ncbi.nlm.nih.gov/gene CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 3p21.31 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000165 (EC: IEP, PMID: 12032188); GO_0001974 (EC: IEA); GO_0002407 (EC: TAS, PMID: 16621978); GO_0003779 (EC: IDA, PMID: 12421915); GO_0004435 (EC: TAS, PMID: 8663314); GO_0004950 (EC: TAS, PMID: 10201901); GO_0005515 (EC: IPI, PMID: 12421915); GO_0005737 (EC: TAS, PMID: 10415069); GO_0005768 (EC: IDA, PMID: 10679098); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 10393923); GO_0006816 (EC: IDA, PMID: 8699119); GO_0006935 (EC: TAS, PMID: 10741397); GO_0006954 (EC: IEA); GO_0006955 (EC: IEA); GO_0006968 (EC: TAS, PMID: 10201901); GO_0007166 (EC: TAS, PMID: 8639485); GO_0007186 (EC: IMP, PMID: 19523456); GO_0007204 (EC: TAS, PMID: 10201901); GO_0007267 (EC: IDA, PMID: 10679098); GO_0009897 (EC: IDA, PMID: 10679098); GO_0009986 (EC: IDA, PMID: 10521508); GO_0014808 (EC: IDA, PMID: 19523456); GO_0015026 (EC: TAS, PMID: 10469138); GO_0016032 (EC: TAS); GO_0016493 (EC: IDA, PMID: 11278962); GO_0016493 (EC: NAS, PMID: 8639485); GO_0019722 (EC: IDA, PMID: 10679098); GO_0019957 (EC: IPI, PMID: 10679098); GO_0023052 (EC: IEP, PMID: 12032188); GO_0030260 (EC: TAS); GO_0070098 (EC: IDA, PMID: 11278962); GO_0070098 (EC: NAS, PMID: 8639485); GO_0070098 (EC: TAS, PMID: 10201901); GO_0070723 (EC: IMP, PMID: 19523456); GO_0071222 (EC: IEP, PMID: 10679098); GO_0071791 (EC: IPI, PMID: 8699119); GO_0090026 (EC: IEA) PMID: 2183196; 2564392; 2569467; 2834384; 3346208; 3512269; 3960725; 8639485; 8649511; 8649512; 8663314; 8674119; 8699119; 8751444; 8756719; 8805353; 8898753; 8906795; 8906796; 8976200; 8995603; 9020356; 9031325; 9143512; 9184207; 9188565; 9207783; 9256481; 9261346; 9261451; 9289016; 9334377; 9343222; 9353123; 9359654; 9359702; 9362541; 9388201; 9399903; 9420225; 9420238; 9445013; 9446638; 9468473; 9525683; 9576751; 9576954; 9632396; 9636210; 9653051; 9653130; 9765440; 9870313; 9882290; 9882373; 9890944; 9971818; 10029247; 10037796; 10085131; 10089882; 10200301; 10201901; 10229873; 10339592; 10357469; 10364178; 10370370; 10384144; 10393923; 10393974; 10413516; 10415069; 10438703; 10438870; 10446313; 10449282; 10453044; 10465086; 10469138; 10477567; 10477718; 10482561; 10482572; 10487781; 10497246; 10505675; 10521508; 10527688; 10544150; 10555208; 10559284; 10562492; 10574939; 10585143; 10590105; 10590121; 10602038; 10602409; 10606089; 10623731; 10640778; 10644351; 10679098; 10702689; 10725362; 10738970; 10741397; 10751368; 10758170; 10775626; 10801487; 10807185; 10816381; 10820198; 10823934; 10826481; 10872839; 10877489; 10882583; 10888615; 10888639; 10917742; 10938094; 10961858; 10970739; 10985308; 11005830; 11023492; 11023526; 11024154; 11069996; 11072599; 11085751; 11086073; 11115360; 11116158; 11118070; 11125885; 11125899; 11134270; 11141322; 11153675; 11162839; 11175286; 11177400; 11181160; 11188946; 11196681; 11196706; 11238869; 11263244; 11264152; 11264346; 11264367; 11265761; 11274729; 11278567; 11278738; 11278962; 11290759; 11312658; 11313374; 11334429; 11335892; 11336643; 11342415; 11350939; 11354628; 11356952; 11356961; 11356967; 11369664; 11377705; 11385319; 11390601; 11393656; 11397808; 11398114; 11403814; 11413305; 11414813; 11427892; 11429110; 11447384; 11448957; 11449371; 11464139; 11468147; 11470772; 11477473; 11484163; 11485305; 11485615; 11489906; 11500196; 11504955; 11511825; 11517394; 11529558; 11543895; 11559423; 11591716; 11595595; 11596075; 11602715; 11679153; 11679916; 11689632; 11693435; 11694103; 11696224; 11698270; 11698699; 11700073; 11703822; 11709091; 11709782; 11711617; 11727771; 11729511; 11733580; 11734558; 11751947; 11752157; 11756347; 11781692; 11803051; 11809184; 11856781; 11859127; 11860793; 11860823; 11861850; 11861874; 11873082; 11876757; 11877445; 11878912; 11901272; 11920312; 11920324; 11937056; 11958683; 11964548; 11966764; 11966770; 11988632; 11994442; 11994538; 12001056; 12010355; 12023175; 12032188; 12032878; 12036855; 12055576; 12056598; 12065593; 12070001; 12082592; 12085329; 12091904; 12093918; 12131184; 12136242; 12140749; 12163044; 12163614; 12166499; 12169668; 12176010; 12183462; 12200385; 12201365; 12202222; 12215252; 12239139; 12271718; 12355376; 12356205; 12368322; 12377943; 12378793; 12403355; 12403770; 12408990; 12412204; 12413885; 12421915; 12426392; 12426393; 12426633; 12427015; 12429730; 12437612; 12445801; 12447757; 12451219; 12461425; 12462338; 12477875; 12477932; 12490404; 12496074; 12509908; 12514416; 12522035; 12531905; 12532229; 12551992; 12552446; 12555203; 12556692; 12557141; 12571248; 12571520; 12579509; 12584049; 12586555; 12587636; 12599073; 12610055; 12610158; 12612298; 12612937; 12619446; 12634405; 12651900; 12667818; 12680626; 12688247; 12689409; 12692222; 12726730; 12745546; 12751031; 12767984; 12788308; 12798016; 12815099; 12819030; 12829440; 12837756; 12846056; 12853745; 12857973; 12858455; 12865070; 12871111; 12873764; 12873765; 12874407; 12882661; 12884524; 12887913; 12887918; 12913933; 12915585; 12925765; 12960231; 12960247; 12963807; 12964123; 14501804; 14505910; 14517611; 14533004; 14533983; 14576050; 14581567; 14583186; 14597737; 14616291; 14624371; 14636691; 14637022; 14644028; 14645006; 14647058; 14672331; 14673528; 14674010; 14694113; 14697747; 14715575; 14716309; 14742283; 14963124; 14981141; 14982745; 14990703; 15000812; 15001559; 15004773; 15009175; 15016843; 15039132; 15047829; 15076247; 15080861; 15086346; 15086398; 15113926; 15117454; 15124759; 15125257; 15135805; 15140377; 15169555; 15180829; 15181567; 15192272; 15192276; 15215889; 15230854; 15236615; 15242539; 15251452; 15258189; 15279544; 15280786; 15288441; 15301862; 15302103; 15307921; 15308751; 15319853; 15321703; 15331395; 15354329; 15362666; 15385740; 15458467; 15465089; 15479838; 15488313; 15489334; 15500552; 15548261; 15557916; 15566517; 15575507; 15577536; 15585333; 15586413; 15588345; 15591779; 15592455; 15596839; 15602133; 15610230; 15629079; 15639953; 15650194; 15651660; 15708547; 15725749; 15737629; 15754978; 15757671; 15767435; 15767436; 15769362; 15787642; 15793360; 15793370; 15802968; 15807900; 15821335; 15851912; 15854903; 15856455; 15857992; 15863470; 15882964; 15885315; 15890935; 15902300; 15916792; 15932625; 15950936; 15958832; 15962231; 15964018; 15964389; 15972662; 15976369; 15980670; 15980693; 15981170; 15983047; 15985194; 15992849; 16015368; 16034118; 16055130; 16100775; 16118671; 16140745; 16144840; 16157597; 16161154; 16174786; 16179731; 16182378; 16196460; 16206074; 16233918; 16248677; 16249462; 16249700; 16261210; 16270124; 16284527; 16286055; 16300985; 16305685; 16312181; 16314800; 16323127; 16335661; 16344560; 16358723; 16375941; 16378977; 16395252; 16405836; 16418398; 16442182; 16461193; 16476734; 16476981; 16478397; 16480760; 16481131; 16485782; 16501811; 16512757; 16513874; 16524739; 16529059; 16541097; 16545485; 16547971; 16598837; 16614115; 16621960; 16621978; 16631222; 16633049; 16641997; 16672419; 16672549; 16702010; 16703416; 16721228; 16721558; 16764352; 16774544; 16775617; 16807236; 16817962; 16841089; 16847113; 16855620; 16865553; 16872485; 16879946; 16887960; 16888899; 16909455; 16916647; 16937446; 16943294; 16960780; 16963439; 16966601; 16999868; 16999983; 17030448; 17053144; 17053352; 17060059; 17063508; 17067435; 17079285; 17091019; 17094383; 17101151; 17101166; 17112859; 17121788; 17135764; 17145599; 17147503; 17148969; 17166523; 17169533; 17202224; 17207111; 17210123; 17214851; 17237417; 17240189; 17255952; 17257590; 17261788; 17273779; 17301575; 17305874; 17306322; 17328229; 17329448; 17331026; 17331851; 17346133; 17351762; 17355643; 17361671; 17383752; 17411375; 17413295; 17417600; 17426779; 17428349; 17442950; 17445875; 17460174; 17462514; 17465678; 17507467; 17507486; 17511851; 17522201; 17530006; 17560067; 17564248; 17565662; 17582634; 17585540; 17596666; 17604289; 17607321; 17620369; 17625759; 17627030; 17633563; 17640964; 17644519; 17645788; 17653092; 17671738; 17672867; 17675516; 17686153; 17691823; 17703412; 17713445; 17722977; 17786209; 17845302; 17855336; 17855654; 17884183; 17901336; 17909797; 17920529; 17929678; 17952079; 17963165; 17971448; 17971457; 17977968; 17984846; 17989610; 18036244; 18060801; 18076768; 18094161; 18096812; 18097239; 18160142; 18162443; 18179388; 18179389; 18182569; 18189189; 18191728; 18194353; 18195571; 18197127; 18203956; 18205260; 18205925; 18218038; 18230715; 18240029; 18242797; 18255039; 18295459; 18296630; 18311470; 18346864; 18353949; 18353956; 18361062; 18379014; 18386165; 18391751; 18405329; 18436884; 18453587; 18462992; 18468560; 18480458; 18480460; 18490657; 18498240; 18500445; 18511806; 18524826; 18543610; 18577758; 18588983; 18590744; 18611987; 18619974; 18623133; 18629619; 18632580; 18633131; 18648518; 18673537; 18676680; 18689270; 18691022; 18692212; 18706447; 18753930; 18763111; 18776933; 18781860; 18786994; 18814951; 18815295; 18820725; 18845960; 18846999; 18855658; 18923649; 18925934; 18928397; 18941536; 18949389; 18952441; 18972295; 18974840; 18977142; 18989363; 18991615; 19005677; 19017985; 19017998; 19018669; 19028820; 19032065; 19037908; 19050382; 19064579; 19064722; 19098363; 19116725; 19124913; 19129082; 19129457; 19131662; 19143484; 19149577; 19155524; 19170196; 19170639; 19172482; 19196047; 19200444; 19201454; 19212663; 19218218; 19225544; 19247692; 19250219; 19258923; 19260142; 19263529; 19289833; 19297481; 19321618; 19334035; 19339951; 19339953; 19357773; 19389855; 19402700; 19420105; 19433914; 19460331; 19474452; 19476483; 19479237; 19479371; 19506371; 19520154; 19523456; 19535121; 19538721; 19553544; 19559392; 19561149; 19578796; 19585516; 19603542; 19625176; 19625411; 19644155; 19644158; 19669591; 19679608; 19680536; 19692168; 19692476; 19692480; 19700905; 19706316; 19722264; 19729379; 19740335; 19744036; 19744740; 19769961; 19811270; 19811439; 19816596; 19841162; 19864932; 19874552; 19886839; 19894308; 19913121; 19917679; 19950235; 19956635; 19958843; 20018238; 20025530; 20025985; 20038229; 20050936; 20053336; 20068218; 20075058; 20087947; 20107582; 20130232; 20153665; 20169157; 20174557; 20182805; 20190752; 20203694; 20206716; 20220260; 20237496; 20331378; 20334567; 20364409; 20377425; 20378664; 20381825; 20411675; 20420684; 20442634; 20442662; 20453841; 20463745; 20465832; 20503287; 20507591; 20518834; 20530467; 20531015; 20536507; 20570309; 20594957; 20598754; 20603037; 20608170; 20628086; 20628649; 20682662; 20710056; 20729133; 20801883; 20811274; 20842205; 20855251; 20856130; 20861743; 20865789; 20875295; 20921899; 20923564; 20932773; 20969781; 21041313; 21068438; 21084992; 21091093; 21118814; 21132346; 21134114; 21148810; 21152581; 21155586; 21156032; 21188555; 21248683; 21258050; 21280323; 21284403; 21288812; 21288824; 21288827; 21295814; 21325401; 21330910; 21345957; 21349294; 21354457; 21356539; 21362450; 21381021; 21388649; 21396623; 21429204; 21454526; 21465943; 21473821; 21513481; 21525208; 21555814; 21569409; 21573951; 21592988; 21602126; 21634220; 21637819; 21647388; 21655330; 21663455; 21667221; 21671175; 21676905; 21680525; 21696586; 21703201; 21709449; 21715437; 21723943; 21731496; 21739422; 21741662; 21744265; 21760891; 21763489; 21775441; 21789236; 21814863; 21819370; 21820915; 21835796; 21846359; 21859712; 21860345; 21878623; 21886032; 21890375; 21926353; 21926633; 21944757; 21984373; 21984929; 21988832; 22011385; 22024519; 22026334; 22028271; 22044225; 22047989; 22050776; 22069466; 22079021; 22083068; 22085486; 22102307; 22103833; 22103834; 22157596; 22175768; 22218121; 22264071; 22265023; 22282138; 22285384; 22286874; 22292949; 22297516; 22313935; 22314435; 22325341; 22342838; 22348061; 22374185; 22380870; 22392992; 22403408; 22404213; 22416573; 22424737; 22479344; 22496149; 22496885; 22506069; 22537745; 22547820; 22554649; 22554651; 22583417; 22612293; 22637726; 22638733; 22657741; 22665517; 22701041; 22727097; 22728273; 22732432; 22787219; 22808111; 22811524; 22815758; 22818666; 22830600; 22852142; 22862553; 22875513; 22893032; 22908191; 22918850; 22924548; 22933279; 22954962; 22957026; 22957692; 22966075; 22988032; 22994752; 23041556; 23057571; 23077246; 23115275; 23152559; 23185351; 23217182; 23217400; 23235831; 23250822; 23289212; 23298254; 23312573; 23355876; 23454776; 23480650; 23490419; 23493400; 23515570; 23588722; 23594959; 23632061; 23632983; 23643185; 23691059; 23696662; 23753295; 23773920; 23852305; 23856897; 23880174; 23888779; 23903010; 23936229; 23954573; 24030490; 24078580; 24090135; 24128342; 24129241; 24405814 chemokine (C-C motif) receptor 5 (gene/pseudogene) Ensembl:ENSG00000160791 HGNC:1606 HPRD:03223 MIM:601373 Vega:OTTHUMG00000133481 CCR5 Bin Zhao, Yue Liu, Oliver He BN-1 C-C CKR-6 CC-CKR-6 CCR-6 CD196 CKR-L3 CKRL3 CMKBR6 DCR2 DRY6 GPR29 GPRCY4 STRL22 WEB: http://www.ncbi.nlm.nih.gov/gene CCR6 chemokine (C-C motif) receptor 6 1235 6q27 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0002407 (EC: TAS, PMID: 16621978); GO_0004872 (EC: TAS, PMID: 9186513); GO_0004950 (EC: TAS, PMID: 11001880); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 9186513); GO_0006928 (EC: TAS, PMID: 9186513); GO_0006935 (EC: TAS, PMID: 11001880); GO_0006955 (EC: TAS, PMID: 9223454); GO_0006959 (EC: TAS, PMID: 11001880); GO_0006968 (EC: TAS, PMID: 10521347); GO_0007165 (EC: TAS, PMID: 9186513); GO_0007204 (EC: TAS, PMID: 9223454); GO_0016493 (EC: IEA); GO_0045087 (EC: TAS); GO_0070098 (EC: TAS, PMID: 11001880) PMID: 2834384; 8125298; 8886020; 9070937; 9169459; 9186513; 9223454; 9294137; 9294138; 10521347; 11001880; 11164896; 11714836; 11751947; 11994436; 12067311; 12070001; 12081481; 12149255; 12193700; 12477932; 12514792; 12642342; 14574404; 15483227; 15489334; 15591779; 15701269; 15972662; 16095490; 16215992; 16344560; 16621978; 16622267; 16641550; 17075975; 17133360; 17171755; 17562763; 17615381; 18097022; 18218038; 18240029; 18465142; 18577758; 18587394; 18703490; 19233848; 19249008; 19305396; 19324905; 19423540; 19492413; 19539215; 19760754; 19811428; 20022113; 20023216; 20056178; 20068036; 20194631; 20220766; 20334681; 20379614; 20406964; 20438785; 20439195; 20453841; 20453842; 20459729; 20483750; 20511548; 20526339; 20526340; 20570966; 20634891; 20720211; 20872189; 21072187; 21092675; 21102463; 21228329; 21261017; 21300824; 21398606; 21624121; 21724701; 21763254; 21873313; 21912453; 21935436; 21937703; 21949768; 21984702; 22079021; 22092173; 22269120; 22490506; 22732549; 22796894; 22842622; 22859539; 22926920; 23128233; 23306142; 23599932; 23681234; 23758411; 23765988; 23790181; 23850713; 23935994; 23983073 chemokine (C-C motif) receptor 6 Ensembl:ENSG00000112486 HGNC:1607 HPRD:03498 MIM:601835 Vega:OTTHUMG00000016015 CCR6 Bin Zhao, Yue Liu, Oliver He BLR2 CD197 CDw197 CMKBR7 EBI1 WEB: http://www.ncbi.nlm.nih.gov/gene CCR7 chemokine (C-C motif) receptor 7 1236 17q12-q21.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0001768 (EC: IC, PMID: 12729902); GO_0001954 (EC: IC, PMID: 15569314); GO_0002407 (EC: IC, PMID: 15778365); GO_0002408 (EC: IC, PMID: 14592837); GO_0002606 (EC: ISS); GO_0002885 (EC: ISS); GO_0002922 (EC: ISS); GO_0004930 (EC: TAS, PMID: 16621978); GO_0005622 (EC: IDA); GO_0005886 (EC: IDA); GO_0005886 (EC: TAS); GO_0006954 (EC: NAS, PMID: 14592837); GO_0006955 (EC: IEA); GO_0007186 (EC: TAS, PMID: 16621978); GO_0007204 (EC: TAS, PMID: 9153236); GO_0009897 (EC: IEA); GO_0016021 (EC: IEA); GO_0016493 (EC: ISS); GO_0030838 (EC: IC, PMID: 11242036); GO_0031274 (EC: IC, PMID: 11242036); GO_0031529 (EC: IC, PMID: 15569314); GO_0032496 (EC: IEA); GO_0032649 (EC: ISS); GO_0032735 (EC: ISS); GO_0032862 (EC: IC, PMID: 15778365); GO_0034695 (EC: IC, PMID: 14592837); GO_0035757 (EC: IPI, PMID: 9507024); GO_0035758 (EC: IPI, PMID: 9507024); GO_0038115 (EC: IDA, PMID: 9507024); GO_0038116 (EC: IDA, PMID: 9507024); GO_0038117 (EC: IDA, PMID: 9507024); GO_0038121 (EC: IDA, PMID: 9507024); GO_0043123 (EC: IC, PMID: 15059845); GO_0043552 (EC: IC, PMID: 15059845); GO_0045060 (EC: IEA); GO_0045785 (EC: IC, PMID: 15569314); GO_0045860 (EC: IC, PMID: 14592837); GO_0046330 (EC: IC, PMID: 15778365); GO_0050706 (EC: ISS); GO_0050862 (EC: IEA); GO_0051209 (EC: IC, PMID: 14592837); GO_0051491 (EC: IC, PMID: 15569314); GO_0051897 (EC: IC, PMID: 15059845); GO_0070098 (EC: ISS); GO_0070374 (EC: IC, PMID: 12729902); GO_0071731 (EC: IC, PMID: 16249377); GO_0072610 (EC: ISS); GO_0090023 (EC: IDA); GO_0097022 (EC: TAS, PMID: 18379575); GO_0097029 (EC: ISS); GO_2000107 (EC: IC, PMID: 15059845); GO_2000147 (EC: IC, PMID: 15778365); GO_2000510 (EC: ISS); GO_2000522 (EC: ISS); GO_2000525 (EC: ISS); GO_2000526 (EC: ISS); GO_2000547 (EC: ISS) PMID: 2834384; 7488016; 7851893; 8383238; 8889548; 9153236; 9507024; 9585422; 9725259; 9743376; 10607681; 10706668; 10741397; 10861057; 11145663; 11242036; 11359797; 11507220; 11830455; 11861876; 11929789; 11970971; 12023337; 12070001; 12149218; 12477932; 12486098; 12642342; 12673677; 12729902; 12799021; 12851649; 14592837; 14990723; 15034011; 15040017; 15059845; 15073111; 15122702; 15247147; 15265234; 15284247; 15304089; 15489334; 15569314; 15674360; 15743472; 15753377; 15778365; 15867478; 15950936; 15972662; 16115904; 16223574; 16225771; 16249377; 16272303; 16278001; 16278374; 16278415; 16344560; 16494043; 16500130; 16621978; 16690519; 16786131; 16802356; 16857986; 16887149; 17006331; 17032700; 17178876; 17192395; 17431094; 17440035; 17587445; 17687340; 17890452; 18065728; 18166500; 18235009; 18240029; 18310327; 18319253; 18379575; 18437055; 18497951; 18544997; 18577758; 18623114; 18664492; 18696160; 18802075; 19068542; 19074885; 19087620; 19136936; 19196101; 19287948; 19423540; 19513547; 19536265; 19536742; 19540558; 19585516; 19615795; 19731977; 19749090; 19862774; 20029460; 20036791; 20056178; 20150960; 20237496; 20406964; 20438785; 20439195; 20651394; 20811680; 20855251; 20889506; 20889923; 21048031; 21071608; 21081040; 21092675; 21165563; 21165582; 21261017; 21347514; 21464944; 21548969; 21624121; 21680174; 21698152; 21731495; 21735098; 21739164; 21739671; 21953548; 22020953; 22043010; 22158872; 22163030; 22221265; 22251626; 22334704; 22350183; 22438908; 22498742; 22533989; 22619482; 22634622; 22659045; 22718198; 22797918; 22821963; 22842622; 22923218; 22990666; 23028633; 23290307; 23363813; 23449735; 23469143; 23498789; 23519840; 23747721; 23888080; 23922113; 24052640; 24136650; 24138884; 24311382 chemokine (C-C motif) receptor 7 Ensembl:ENSG00000126353 HGNC:1608 HPRD:02588 MIM:600242 Vega:OTTHUMG00000133375 CCR7 Bin Zhao, Yue Liu, Oliver He CC-CKR-8 CCR-8 CDw198 CKRL1 CMKBR8 CMKBRL2 CY6 GPRCY6 TER1 WEB: http://www.ncbi.nlm.nih.gov/gene CCR8 chemokine (C-C motif) receptor 8 1237 3p22 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0004950 (EC: TAS, PMID: 9417093); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 8816377); GO_0006935 (EC: IEA); GO_0006955 (EC: IEA); GO_0007155 (EC: TAS, PMID: 10910894); GO_0007186 (EC: TAS, PMID: 8816377); GO_0007204 (EC: IEA); GO_0015026 (EC: TAS, PMID: 9417093); GO_0016493 (EC: IEA); GO_0070098 (EC: TAS, PMID: 9417093) PMID: 8816377; 8886020; 8977299; 9207005; 9211859; 9417093; 9469461; 9480837; 9521068; 9670926; 10469138; 10540332; 10888633; 10910894; 11007922; 11804551; 12163566; 12477932; 12525579; 12547701; 12551893; 12645948; 12832759; 12967681; 14576057; 15053339; 15489334; 15814739; 15992849; 16631222; 17023422; 17082609; 17558413; 17641040; 17693327; 18240029; 18577758; 19074885; 19423540; 20237496; 20406964; 20438785; 20455898; 21976223; 22479563; 22842622; 23043070; 23363815; 23999500 chemokine (C-C motif) receptor 8 Ensembl:ENSG00000179934 HGNC:1609 HPRD:03497 MIM:601834 Vega:OTTHUMG00000131290 CCR8 Bin Zhao, Yue Liu, Oliver He CNP1 WEB: http://www.ncbi.nlm.nih.gov/gene CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1267 17q21 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000226 (EC: IEA); GO_0003723 (EC: IEA); GO_0004113 (EC: IEA); GO_0005615 (EC: IDA, PMID: 12379507); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005741 (EC: IEA); GO_0005743 (EC: IEA); GO_0005874 (EC: IDA); GO_0005886 (EC: IEA); GO_0005902 (EC: IEA); GO_0007268 (EC: TAS, PMID: 1322358); GO_0007409 (EC: IEA); GO_0007568 (EC: IEA); GO_0008344 (EC: IEA); GO_0009214 (EC: IEA); GO_0009636 (EC: IEA); GO_0021762 (EC: IEP); GO_0030551 (EC: IEA); GO_0031143 (EC: IEA); GO_0032496 (EC: IEA); GO_0035748 (EC: IEA); GO_0035749 (EC: IEA); GO_0042470 (EC: IEA); GO_0046902 (EC: IEA); GO_0048471 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1315529; 1322358; 1360194; 1385234; 2161933; 2164018; 2835044; 2995854; 6328143; 7821789; 8392017; 8921398; 9268698; 10646504; 11156964; 11842207; 11993850; 12379507; 12452325; 12477932; 12643545; 12947117; 14702039; 15489334; 15502338; 15713463; 16103231; 16343930; 16389193; 16891421; 17010574; 17081065; 17150526; 17215244; 17306456; 17964117; 18289148; 18482256; 18496213; 18676363; 19034380; 19056867; 19165527; 19348671; 19508346; 19913121; 20628086; 21139048; 21525035; 21890473; 21906983; 22053931; 22321011; 22473874; 22505724; 22589395; 22678362; 22954668; 23000965; 23032943; 23084924; 23455922; 23667531; 24250222 2',3'-cyclic nucleotide 3' phosphodiesterase Ensembl:ENSG00000173786 HGNC:2158 HPRD:00448 MIM:123830 Vega:OTTHUMG00000133502 CNP Bin Zhao, Yue Liu, Oliver He C3BR C4BR CD35 KN WEB: http://www.ncbi.nlm.nih.gov/gene CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1378 RP11-57I17.1 1q32 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001851 (EC: IDA, PMID: 2972794); GO_0001855 (EC: IDA, PMID: 2972794); GO_0001861 (EC: IDA, PMID: 2972794); GO_0002430 (EC: IDA, PMID: 2972794); GO_0004877 (EC: IDA, PMID: 2972794); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 6910481); GO_0006958 (EC: IEA); GO_0009986 (EC: IDA, PMID: 2972794); GO_0030449 (EC: TAS); GO_0045087 (EC: TAS); GO_0045957 (EC: IDA, PMID: 10531307); GO_0045959 (EC: IDA, PMID: 10531307); GO_0070062 (EC: IDA, PMID: 19056867); GO_1900004 (EC: IDA, PMID: 6910481); GO_1900005 (EC: IDA, PMID: 2972794) PMID: 1670949; 1708808; 1708809; 1827486; 2295627; 2411809; 2478758; 2531419; 2551147; 2564414; 2877046; 2933745; 2951479; 2959289; 2971757; 2972794; 2977721; 2989379; 3014040; 3031685; 3155774; 3156931; 3157763; 3305706; 3736743; 3782802; 4019777; 6115248; 6126949; 6222138; 6223944; 6230413; 6572933; 6910481; 6978375; 7690834; 8245463; 8422437; 9089986; 9230440; 9614933; 9988761; 10382758; 10528197; 10528211; 10531307; 10698335; 10737800; 11120776; 11313284; 11694537; 11884446; 11896343; 11955431; 11981823; 12083416; 12091241; 12477932; 12486610; 12490287; 12773320; 12869997; 14556965; 14635039; 14694201; 15069174; 15072851; 15163541; 15176657; 15381817; 15388259; 15526369; 15529364; 15578041; 15660833; 15728520; 15733500; 15864913; 16133175; 16277654; 16289666; 16360013; 16426237; 16433910; 17207243; 17467802; 17709521; 17999656; 18028942; 18075277; 18182380; 18434253; 18684861; 18709693; 18713965; 18842294; 18929826; 18937792; 18954261; 18954403; 19048480; 19056867; 19131551; 19344414; 19480840; 19578791; 19734903; 19874218; 19906204; 19959855; 20237496; 20379614; 20459687; 20534741; 20538029; 20554627; 20558149; 20558387; 20646210; 20670356; 20674675; 20697030; 20702729; 20739100; 20795311; 20855594; 20889874; 20951238; 21251929; 21300948; 21347408; 21358043; 21391232; 21403675; 21459435; 21460840; 21460841; 21593778; 21659422; 21663961; 21700265; 21726919; 21727667; 21784344; 21839519; 21912625; 21985366; 22015308; 22237765; 22244847; 22262751; 22291609; 22333472; 22343410; 22374251; 22402018; 22539578; 22819390; 22888138; 22952074; 22960360; 22962438; 23022416; 23152904; 23202439; 23376460; 23390291; 23416052; 23440418; 23582656; 23591632; 23650005; 24022490; 24214979 complement component (3b/4b) receptor 1 (Knops blood group) Ensembl:ENSG00000203710 HGNC:2334 HPRD:00398 MIM:120620 Vega:OTTHUMG00000036311 CR1 Bin Zhao, Yue Liu, Oliver He CREB WEB: http://www.ncbi.nlm.nih.gov/gene CREB1 cAMP responsive element binding protein 1 1385 2q34 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0000980 (EC: IDA, PMID: 19861239); GO_0001102 (EC: IPI, PMID: 19861239); GO_0001190 (EC: IDA, PMID: 19861239); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0003700 (EC: IDA, PMID: 8798441); GO_0003705 (EC: IDA, PMID: 19861239); GO_0003712 (EC: TAS, PMID: 8552098); GO_0005515 (EC: IPI, PMID: 10722738); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005667 (EC: IEA); GO_0005719 (EC: IDA, PMID: 19861239); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0006366 (EC: IDA, PMID: 19861239); GO_0006468 (EC: IDA, PMID: 8798441); GO_0007165 (EC: TAS); GO_0007173 (EC: TAS); GO_0007202 (EC: TAS); GO_0007219 (EC: TAS); GO_0007268 (EC: TAS); GO_0007411 (EC: TAS); GO_0007595 (EC: IEA); GO_0008361 (EC: IEA); GO_0008543 (EC: TAS); GO_0010033 (EC: IDA, PMID: 8798441); GO_0010944 (EC: IDA, PMID: 19861239); GO_0016032 (EC: IEA); GO_0021983 (EC: IEA); GO_0033363 (EC: IEA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035497 (EC: IDA, PMID: 19861239); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0040018 (EC: IEA); GO_0042493 (EC: IEA); GO_0045087 (EC: TAS); GO_0045600 (EC: ISS); GO_0045672 (EC: IEA); GO_0045893 (EC: ISS); GO_0045944 (EC: IDA, PMID: 19861239); GO_0046887 (EC: IEA); GO_0046889 (EC: ISS); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0050821 (EC: ISS); GO_0051403 (EC: TAS); GO_0060430 (EC: IEA); GO_0060509 (EC: IEA) PMID: 1386673; 1461747; 1655749; 1831258; 1966745; 2138276; 2142119; 2142528; 2974179; 7505393; 7551568; 7554179; 7565761; 7608156; 7619208; 7621901; 7769693; 7809053; 8381074; 8384217; 8449898; 8552098; 8628277; 8663317; 8688081; 8798441; 8887554; 9388250; 9413984; 9558095; 9671480; 9687510; 9770464; 9786917; 9792677; 9829964; 9873047; 10074179; 10506141; 10567391; 10650954; 10720489; 10722738; 10781615; 10848610; 10866654; 10886376; 10909971; 10945975; 11013247; 11018520; 11046156; 11156964; 11160957; 11175347; 11259575; 11313407; 11377386; 11500364; 11564156; 11572863; 11698596; 11909979; 11988318; 12091337; 12145339; 12162494; 12183445; 12196545; 12198160; 12200150; 12220644; 12235136; 12368293; 12391146; 12391222; 12437352; 12477932; 12519783; 12552083; 12567184; 12622660; 12665587; 12676584; 12690113; 12720543; 12743114; 12773552; 12776737; 12805224; 12829027; 12851637; 14506290; 14523007; 14580193; 14597631; 14597636; 14635195; 14646589; 14702039; 14742439; 14754893; 14761884; 14764597; 14962944; 15073328; 15077295; 15082775; 15153340; 15276183; 15340044; 15454081; 15489334; 15500908; 15579595; 15585582; 15588513; 15615708; 15688015; 15691874; 15691881; 15694837; 15703171; 15733869; 15753290; 15806162; 15837624; 15879136; 15897899; 15901830; 15917247; 15961999; 15964553; 15999345; 16007092; 16134057; 16158061; 16169070; 16207717; 16207795; 16223362; 16227528; 16282323; 16293623; 16306050; 16325578; 16330542; 16339753; 16449647; 16483570; 16598418; 16611888; 16675956; 16799563; 16820098; 16822311; 16896160; 16920714; 16963449; 16978443; 16980615; 17082618; 17169345; 17202341; 17276404; 17289023; 17300755; 17310988; 17389598; 17426037; 17449469; 17455223; 17460549; 17476304; 17507637; 17548750; 17565597; 17565598; 17565599; 17565603; 17573727; 17592483; 17646388; 17661722; 17712720; 17724745; 17727817; 17786359; 17805329; 17822787; 17827388; 17889508; 17909078; 17975014; 18022816; 18024382; 18029348; 18034423; 18070920; 18160048; 18189280; 18191017; 18287226; 18375384; 18396147; 18457359; 18483184; 18485898; 18511806; 18554190; 18599546; 18606955; 18626018; 18660489; 18676828; 18678793; 18713830; 18717645; 18775326; 18792986; 18801732; 18922788; 18930904; 18988190; 19001277; 19070599; 19100722; 19113914; 19136032; 19138976; 19156168; 19164291; 19194961; 19196967; 19199539; 19201889; 19211892; 19223597; 19244110; 19251839; 19279000; 19289467; 19298866; 19340314; 19351775; 19416972; 19426590; 19473990; 19517574; 19531482; 19548263; 19553322; 19561568; 19578717; 19614745; 19632326; 19632997; 19718656; 19762740; 19786833; 19797430; 19815709; 19822084; 19822898; 19842072; 19844206; 19861239; 19874574; 19875824; 19913121; 19956847; 20018896; 20032081; 20033853; 20037212; 20089855; 20097716; 20100571; 20101207; 20136501; 20160059; 20198332; 20198339; 20211142; 20219685; 20237496; 20398657; 20402410; 20403362; 20407090; 20407870; 20447464; 20468064; 20473547; 20498639; 20533262; 20536573; 20541704; 20573984; 20599715; 20624818; 20628086; 20643483; 20682687; 20685939; 20693566; 20805990; 20881124; 20936779; 20943350; 20945072; 20974683; 20979795; 21034562; 21044077; 21075212; 21079758; 21084670; 21139048; 21172805; 21212407; 21215389; 21268077; 21295542; 21315782; 21325281; 21398611; 21483768; 21497119; 21598377; 21644508; 21705328; 21706049; 21734652; 21784978; 21816823; 21832046; 21890473; 21956116; 21988832; 21997693; 21998402; 22027994; 22072831; 22127929; 22180334; 22185778; 22198373; 22219277; 22253425; 22267179; 22271686; 22285928; 22293360; 22294156; 22325466; 22349818; 22383952; 22386572; 22469229; 22505473; 22510762; 22531917; 22539488; 22561749; 22570239; 22574704; 22609331; 22627767; 22669896; 22726539; 22743041; 22787115; 22922957; 22939629; 23000965; 23011268; 23019365; 23020846; 23032945; 23038261; 23049845; 23055509; 23086924; 23100280; 23127979; 23143030; 23168992; 23185366; 23195957; 23213254; 23220172; 23382074; 23382855; 23403511; 23417028; 23462962; 23469012; 23494562; 23504989; 23526216; 23532963; 23537502; 23543137; 23619509; 23661758; 23727510; 23814058; 23838680; 23846693; 23857777; 23894352; 23896026; 23979134; 24041570; 24085294; 24233491; 24250222; 24315104 cAMP responsive element binding protein 1 Ensembl:ENSG00000118260 HGNC:2345 HPRD:00442 MIM:123810 Vega:OTTHUMG00000132936 CREB1 Bin Zhao, Yue Liu, Oliver He CRMP-1 DPYSL1 DRP-1 DRP1 ULIP-3 WEB: http://www.ncbi.nlm.nih.gov/gene CRMP1 collapsin response mediator protein 1 1400 4p16.1 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 15383276); GO_0005737 (EC: IDA); GO_0005815 (EC: IEA); GO_0005819 (EC: IEA); GO_0005829 (EC: TAS); GO_0006139 (EC: TAS, PMID: 8973361); GO_0006208 (EC: IEA); GO_0007399 (EC: TAS, PMID: 8973361); GO_0007411 (EC: TAS); GO_0016812 (EC: IEA); GO_0030425 (EC: IEA); GO_0043025 (EC: IEA) PMID: 8973361; 10048489; 11562390; 12134159; 12477932; 12482610; 12650609; 14702039; 14996858; 15383276; 15489334; 15492864; 16169070; 16344560; 16611631; 17118363; 18029348; 18524846; 18782567; 19019082; 19362386; 19903856; 20087401; 20379614; 20506281; 21078624; 21139048; 21747164; 21900206; 22359051; 22363707; 22798627; 22863883; 23720494; 24250222 collapsin response mediator protein 1 Ensembl:ENSG00000072832 HGNC:2365 HPRD:03913 MIM:602462 Vega:OTTHUMG00000125489 CRMP1 Bin Zhao, Yue Liu, Oliver He CSBP CSBP1 CSBP2 CSPB1 EXIP Mxi2 PRKM14 PRKM15 RK SAPK2A p38 p38ALPHA WEB: http://www.ncbi.nlm.nih.gov/gene MAPK14 mitogen-activated protein kinase 14 1432 RP1-179N16.5 6p21.3-p21.2 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000077 (EC: IEA); GO_0000187 (EC: TAS); GO_0000902 (EC: IEA); GO_0000922 (EC: IEA); GO_0001502 (EC: IEA); GO_0001525 (EC: IEA); GO_0002062 (EC: IEA); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004674 (EC: TAS); GO_0004707 (EC: IDA, PMID: 10330143); GO_0004708 (EC: TAS, PMID: 10706854); GO_0005515 (EC: IPI, PMID: 10601328); GO_0005524 (EC: IEA); GO_0005634 (EC: ISS); GO_0005654 (EC: TAS); GO_0005737 (EC: ISS); GO_0005739 (EC: IEA); GO_0005829 (EC: TAS); GO_0006006 (EC: IEA); GO_0006351 (EC: IEA); GO_0006357 (EC: ISS); GO_0006915 (EC: IEA); GO_0006928 (EC: TAS, PMID: 10912793); GO_0006935 (EC: TAS, PMID: 10706854); GO_0007165 (EC: TAS, PMID: 10706854); GO_0007166 (EC: TAS, PMID: 10706854); GO_0007178 (EC: IEA); GO_0007265 (EC: TAS); GO_0007519 (EC: IEA); GO_0007596 (EC: TAS); GO_0010467 (EC: TAS); GO_0010831 (EC: ISS); GO_0016070 (EC: TAS); GO_0016071 (EC: TAS); GO_0018105 (EC: ISS); GO_0019395 (EC: IEA); GO_0030168 (EC: TAS); GO_0030316 (EC: ISS); GO_0031663 (EC: IEA); GO_0032495 (EC: IEA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035556 (EC: IDA, PMID: 10838079); GO_0035666 (EC: TAS); GO_0035924 (EC: IMP, PMID: 18440775); GO_0038066 (EC: ISS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042307 (EC: IEA); GO_0042692 (EC: TAS); GO_0042770 (EC: IMP); GO_0043536 (EC: IMP, Qualifier: NOT, PMID: 18440775); GO_0045087 (EC: TAS); GO_0045648 (EC: IEA); GO_0045663 (EC: ISS); GO_0045944 (EC: IEA); GO_0048010 (EC: IMP, PMID: 18440775); GO_0048011 (EC: TAS); GO_0051090 (EC: TAS); GO_0051146 (EC: IEA); GO_0051149 (EC: TAS); GO_0051403 (EC: TAS); GO_0051525 (EC: ISS); GO_0070935 (EC: TAS); GO_0071479 (EC: IMP); GO_0090090 (EC: IEA); GO_0090400 (EC: IMP); GO_1901741 (EC: ISS); GO_2000379 (EC: IMP) PMID: 1088347; 7479834; 7535770; 7592979; 7696354; 7716521; 7750576; 7839144; 7914033; 7923354; 7997261; 8083223; 8274451; 8530093; 8548291; 8622669; 8626699; 8650547; 8695800; 8798479; 8846784; 8910361; 8910365; 8917518; 9069290; 9092573; 9095200; 9130707; 9155018; 9162092; 9207092; 9211903; 9235954; 9278512; 9295308; 9297626; 9405468; 9434624; 9465032; 9468497; 9554853; 9628874; 9687510; 9753691; 9753748; 9768359; 9788880; 9792677; 9808624; 9858528; 9878398; 9889198; 10085140; 10206983; 10330143; 10346818; 10348343; 10364159; 10391943; 10415025; 10557092; 10559944; 10581258; 10597297; 10601328; 10644717; 10706854; 10708586; 10727080; 10747897; 10779345; 10805738; 10806207; 10838079; 10849446; 10857861; 10878576; 10884347; 10910078; 10912793; 10942774; 10943842; 10961885; 10978317; 10980603; 11042204; 11042694; 11157753; 11226159; 11259586; 11278395; 11278799; 11279118; 11279232; 11333986; 11344273; 11359773; 11377386; 11387337; 11390380; 11408587; 11416124; 11468147; 11489891; 11495898; 11520933; 11551930; 11551945; 11566021; 11602244; 11604491; 11691836; 11698270; 11741533; 11756422; 11773065; 11777913; 11781324; 11788583; 11788789; 11792706; 11839738; 11847341; 11848686; 11852102; 11866441; 11896401; 11988087; 11994045; 11994493; 11997522; 12009331; 12051955; 12054652; 12067303; 12071847; 12085235; 12089333; 12105188; 12110590; 12126643; 12138194; 12164931; 12170268; 12171600; 12183063; 12200131; 12225289; 12232043; 12239168; 12296996; 12324467; 12370831; 12384504; 12391307; 12403788; 12429732; 12473116; 12477932; 12478662; 12505871; 12509443; 12519482; 12581156; 12589052; 12595530; 12606502; 12631076; 12654092; 12663671; 12665511; 12665801; 12684028; 12697749; 12697810; 12698197; 12702497; 12748288; 12761180; 12775419; 12784337; 12810082; 12819782; 12824191; 12829618; 12855667; 12882963; 12897141; 12933809; 12963847; 13679851; 14499342; 14512875; 14552880; 14563843; 14574404; 14578350; 14586399; 14592977; 14648593; 14660488; 14676314; 14714552; 14715645; 14970175; 14989597; 15111488; 15132952; 15133024; 15170913; 15232685; 15245437; 15246972; 15256218; 15257094; 15273249; 15276183; 15284239; 15292176; 15292225; 15304097; 15304486; 15310753; 15315972; 15319438; 15322009; 15345584; 15375157; 15383283; 15388348; 15489334; 15489375; 15514847; 15516490; 15527495; 15541600; 15542843; 15550393; 15567067; 15569672; 15578697; 15592455; 15592496; 15603708; 15625302; 15629715; 15632082; 15634764; 15642743; 15650392; 15665518; 15668322; 15677464; 15688026; 15692053; 15708845; 15717263; 15728454; 15737629; 15737736; 15753227; 15755725; 15778365; 15784503; 15790570; 15791651; 15797859; 15817653; 15833736; 15843433; 15845648; 15849811; 15851480; 15857981; 15862947; 15894558; 15901830; 15917247; 15919053; 15923648; 15946948; 15950779; 15964514; 15972662; 16014723; 16027723; 16027724; 16081599; 16098034; 16099944; 16111829; 16123320; 16133687; 16135815; 16138080; 16139274; 16153249; 16153436; 16164755; 16169070; 16189514; 16197369; 16214108; 16242072; 16251188; 16256071; 16256948; 16257181; 16278378; 16308312; 16338464; 16342939; 16344056; 16344560; 16351573; 16380078; 16410245; 16410316; 16446363; 16456540; 16456544; 16467496; 16469115; 16478922; 16516911; 16532349; 16538384; 16554354; 16581800; 16613612; 16627995; 16636664; 16645187; 16648477; 16648633; 16683917; 16697418; 16699462; 16699726; 16709866; 16720051; 16751104; 16769768; 16790501; 16814421; 16820791; 16841089; 16843435; 16861915; 16864945; 16869889; 16897667; 16899715; 16912047; 16924234; 16924420; 16927023; 16935849; 16949365; 16951426; 16964394; 16973972; 16982329; 17000004; 17012370; 17028194; 17030506; 17030510; 17030608; 17035228; 17050539; 17054722; 17055984; 17059827; 17081983; 17085432; 17088247; 17107667; 17126905; 17141198; 17142767; 17172861; 17182689; 17188240; 17192257; 17196171; 17202341; 17202865; 17207971; 17219054; 17222367; 17229385; 17234706; 17241234; 17244678; 17255097; 17255949; 17277157; 17284314; 17284589; 17303142; 17303382; 17303384; 17307333; 17316568; 17332506; 17334397; 17341442; 17347580; 17373649; 17380123; 17395714; 17404265; 17406030; 17438131; 17442041; 17443309; 17446930; 17453826; 17464174; 17468755; 17519236; 17524358; 17531530; 17543571; 17548351; 17548358; 17570131; 17583675; 17584736; 17585337; 17597823; 17599408; 17604950; 17611702; 17612563; 17613714; 17616668; 17624368; 17628663; 17652082; 17675521; 17689131; 17698513; 17719653; 17720811; 17724032; 17727817; 17879955; 17888403; 17893873; 17906618; 17906919; 17921324; 17927969; 17928890; 17929017; 17959643; 17959827; 17967130; 17974568; 17979814; 17982102; 17991740; 17996717; 18022596; 18028450; 18036649; 18047584; 18054783; 18055026; 18059487; 18065201; 18086809; 18087676; 18089732; 18093851; 18095520; 18160848; 18165231; 18177491; 18211888; 18218858; 18223258; 18224252; 18231754; 18246004; 18247374; 18252806; 18253836; 18275043; 18276609; 18276761; 18288129; 18288130; 18296636; 18296712; 18314537; 18325348; 18353785; 18358530; 18367666; 18371353; 18372245; 18387958; 18389508; 18395970; 18401529; 18405916; 18411303; 18419748; 18424721; 18424756; 18439424; 18440775; 18451303; 18460190; 18477563; 18478240; 18482988; 18487214; 18487954; 18495129; 18502748; 18541226; 18541673; 18559936; 18563362; 18571150; 18586681; 18607537; 18613029; 18624398; 18625709; 18632968; 18642443; 18660489; 18667601; 18675993; 18678875; 18682391; 18692180; 18695917; 18703508; 18718914; 18723442; 18725314; 18727065; 18727093; 18728014; 18757346; 18758450; 18760861; 18776133; 18799583; 18806262; 18813787; 18814027; 18827744; 18830681; 18854640; 18922473; 18949384; 18949386; 18949619; 18953413; 18953958; 18954908; 18986328; 18987975; 19010591; 19015318; 19023333; 19047046; 19048100; 19073744; 19074436; 19074832; 19088256; 19091131; 19112161; 19124752; 19129540; 19138820; 19152512; 19152916; 19164129; 19192109; 19196344; 19209848; 19214751; 19231233; 19242520; 19251701; 19254690; 19265690; 19267882; 19268365; 19270308; 19280689; 19286308; 19287189; 19289404; 19319478; 19319745; 19324082; 19343039; 19351724; 19362680; 19364817; 19365146; 19371952; 19389701; 19407223; 19418584; 19430204; 19433314; 19448675; 19453261; 19467570; 19468799; 19471022; 19479051; 19482949; 19497411; 19501598; 19506078; 19520742; 19520919; 19528229; 19539632; 19540572; 19543489; 19565356; 19570915; 19571577; 19584293; 19608729; 19628771; 19631608; 19633425; 19635790; 19638579; 19648294; 19656390; 19676104; 19676105; 19692652; 19698994; 19700666; 19706373; 19706521; 19713744; 19723092; 19723095; 19726550; 19727814; 19736361; 19748889; 19781349; 19801633; 19822084; 19828631; 19837302; 19851890; 19862774; 19874574; 19885551; 19885574; 19885589; 19887452; 19893453; 19893488; 19901160; 19906316; 19913121; 19913910; 19915152; 19917608; 19920075; 19940360; 19948725; 19950901; 19996096; 20043086; 20051382; 20053787; 20056178; 20060003; 20066900; 20068037; 20069553; 20070945; 20072629; 20085806; 20086174; 20090955; 20093368; 20155832; 20162623; 20169663; 20171194; 20181932; 20188673; 20212154; 20213747; 20223287; 20231411; 20299663; 20307495; 20339548; 20345761; 20345980; 20347265; 20368287; 20378550; 20379614; 20380698; 20393480; 20396861; 20414969; 20430109; 20432471; 20434230; 20460375; 20462950; 20463961; 20467438; 20473571; 20483734; 20505830; 20511681; 20514473; 20519498; 20525893; 20530479; 20552237; 20558744; 20562859; 20564243; 20564821; 20573801; 20588308; 20610713; 20619728; 20628086; 20629536; 20631726; 20647313; 20660302; 20674992; 20677014; 20682780; 20686359; 20702616; 20729202; 20729213; 20734064; 20736797; 20797629; 20798394; 20799279; 20803566; 20805296; 20825716; 20849923; 20855878; 20871633; 20921877; 20936779; 20945383; 20957493; 20960177; 21044959; 21048031; 21078676; 21085594; 21097678; 21098640; 21121046; 21139048; 21146537; 21152872; 21165580; 21172429; 21174002; 21177868; 21187925; 21195543; 21199725; 21206905; 21210297; 21220911; 21244757; 21262998; 21273059; 21283629; 21286833; 21292162; 21308746; 21321117; 21374592; 21413023; 21429433; 21444723; 21448845; 21498515; 21519792; 21547253; 21567397; 21569377; 21574189; 21575499; 21606198; 21659629; 21675959; 21816217; 21816898; 21858220; 21872446; 21890458; 21890473; 21900206; 21907836; 21908610; 21923922; 21926353; 21948112; 21959016; 21963094; 21982020; 21982916; 21988832; 21992459; 21993219; 22020907; 22020916; 22053010; 22053931; 22056876; 22064321; 22068056; 22073300; 22076613; 22092597; 22095154; 22117196; 22128155; 22138711; 22154358; 22158075; 22164217; 22164285; 22167332; 22226621; 22229442; 22258405; 22266858; 22267390; 22302987; 22307324; 22310643; 22351694; 22357202; 22375047; 22375048; 22407921; 22409248; 22413835; 22447027; 22490020; 22504301; 22506718; 22518842; 22521293; 22521508; 22522454; 22555972; 22572461; 22652417; 22696064; 22696230; 22727776; 22743041; 22763042; 22768308; 22773734; 22774404; 22777388; 22828869; 22843747; 22850347; 22854965; 22863019; 22863883; 22868770; 22875631; 22886009; 22905203; 22931618; 22939629; 22965824; 22983351; 23024367; 23029125; 23038261; 23047944; 23056170; 23079240; 23088735; 23088768; 23109423; 23116132; 23125442; 23152511; 23175675; 23185379; 23206705; 23235200; 23235332; 23258237; 23269672; 23271722; 23308187; 23315073; 23319595; 23331010; 23332156; 23335506; 23354626; 23402824; 23403951; 23416061; 23416140; 23444236; 23446663; 23455922; 23456625; 23474535; 23483889; 23498167; 23507189; 23523631; 23532963; 23546865; 23557259; 23562842; 23579276; 23602274; 23602568; 23615713; 23619266; 23625220; 23640483; 23671282; 23679818; 23685072; 23690655; 23732112; 23734265; 23759594; 23762436; 23771849; 23792164; 23798571; 23799978; 23836902; 23847446; 23859194; 23893408; 23901045; 23916702; 23926106; 23929359; 23932588; 23935096; 23935100; 23993976; 24021264; 24189062; 24257756; 24269888; 24347047 mitogen-activated protein kinase 14 Ensembl:ENSG00000112062 HGNC:6876 HPRD:02619 MIM:600289 Vega:OTTHUMG00000159806 MAPK14 Bin Zhao, Yue Liu, Oliver He CAS CSE1 XPO2 WEB: http://www.ncbi.nlm.nih.gov/gene CSE1L CSE1 chromosome segregation 1-like (yeast) 1434 20q13 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 17719542); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0006611 (EC: TAS, PMID: 9323134); GO_0006915 (EC: TAS, PMID: 7479798); GO_0008262 (EC: TAS, PMID: 9323134); GO_0008283 (EC: TAS, PMID: 7479798); GO_0008536 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 7479798; 8125298; 8639641; 8943292; 8963895; 9323134; 9428644; 9786944; 10331944; 10523667; 11295109; 11310559; 11703094; 11724300; 11780052; 11927559; 12061792; 12477932; 12510150; 12972425; 14718574; 15161933; 15324660; 15489334; 16169070; 16196087; 16786158; 17110338; 17314511; 17719542; 18051367; 18377724; 18425415; 18439902; 18457437; 18781797; 19056867; 19224336; 19471022; 19615732; 19738201; 20016921; 20150437; 20473970; 20734115; 20936779; 21081666; 21139048; 21252943; 21290345; 21319273; 21343306; 21693764; 21890473; 21906983; 21963094; 21983832; 21987572; 22053931; 22110766; 22268729; 22476051; 22586326; 22623428; 22653741; 22678362; 22711543; 22863883; 22939629; 22952058; 22967991; 23000965; 23181366; 23189846; 23455922; 23464991; 23703321; 23806821; 23862649; 23956138; 24250222; 24457600 CSE1 chromosome segregation 1-like (yeast) Ensembl:ENSG00000124207 HGNC:2431 HPRD:03217 MIM:601342 Vega:OTTHUMG00000033046 CSE1L Bin Zhao, Yue Liu, Oliver He CSF-1 MCSF WEB: http://www.ncbi.nlm.nih.gov/gene CSF1 colony stimulating factor 1 (macrophage) 1435 RP11-195M16.2 1p13.3 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001503 (EC: IEA); GO_0001954 (EC: ISS, PMID: 18566389); GO_0002158 (EC: IEA); GO_0003006 (EC: ISS, PMID: 19017797); GO_0005125 (EC: IDA, PMID: 10652277); GO_0005157 (EC: ISS, PMID: 19017797); GO_0005157 (EC: TAS, PMID: 2460758); GO_0005615 (EC: IDA, PMID: 2460758); GO_0005886 (EC: IEA); GO_0006954 (EC: IEA); GO_0008083 (EC: IDA, PMID: 2460758); GO_0008083 (EC: NAS, PMID: 1791839); GO_0008283 (EC: NAS, PMID: 1791839); GO_0008284 (EC: IDA, PMID: 10652277); GO_0008284 (EC: TAS, PMID: 2460758); GO_0010628 (EC: IDA, PMID: 10666185); GO_0010743 (EC: NAS, PMID: 18566389); GO_0010744 (EC: IDA, PMID: 17244792); GO_0016020 (EC: NAS, PMID: 2460758); GO_0016021 (EC: IEA); GO_0030097 (EC: NAS, PMID: 1791839); GO_0030154 (EC: NAS, PMID: 1791839); GO_0030225 (EC: TAS, PMID: 2460758); GO_0030278 (EC: IEA); GO_0030316 (EC: IDA, PMID: 18606301); GO_0030335 (EC: ISS, PMID: 18566389); GO_0032270 (EC: IDA, PMID: 1739124); GO_0032946 (EC: IDA, PMID: 2460758); GO_0040018 (EC: IEA); GO_0042117 (EC: NAS, PMID: 18566389); GO_0042476 (EC: IEA); GO_0042488 (EC: IEA); GO_0042803 (EC: IDA, PMID: 3264878); GO_0043235 (EC: ISS, PMID: 19017797); GO_0045087 (EC: IEA); GO_0045651 (EC: IDA, PMID: 2460758); GO_0045657 (EC: ISS, PMID: 18566389); GO_0045672 (EC: IDA, PMID: 15304486); GO_0045860 (EC: ISS, PMID: 18566389); GO_0046579 (EC: IEA); GO_0048471 (EC: IDA, PMID: 1739124); GO_0048873 (EC: IEA); GO_0060444 (EC: IEA); GO_0060611 (EC: IEA); GO_0060763 (EC: IEA) PMID: 1334406; 1455231; 1531650; 1540160; 1571567; 1733926; 1739124; 1791839; 2145044; 2408759; 2460758; 2660794; 2996129; 3039346; 3259875; 3264877; 3264878; 3493529; 3498652; 3500041; 7696959; 8086034; 8262907; 8336080; 8355686; 8422357; 8804363; 8981357; 9131001; 9147389; 9632647; 10652277; 10666185; 10857771; 11248655; 11297560; 11369790; 11387343; 11739737; 11792569; 11843897; 12032835; 12372416; 12393446; 12411027; 12456016; 12477932; 12501178; 12548211; 12684699; 12749918; 12790839; 12865350; 12890905; 12894871; 12928417; 12929928; 14605992; 14634568; 14654075; 15001836; 15116247; 15256272; 15261158; 15304486; 15358207; 15489334; 15494511; 15576295; 15624698; 15640942; 15728521; 15780937; 15820145; 15866728; 15919699; 15944252; 16204228; 16267391; 16318581; 16320327; 16344560; 16407111; 16673212; 16844084; 16859503; 16951369; 17108334; 17192722; 17243911; 17244792; 17353186; 17355643; 17368603; 17420255; 17431224; 17443671; 17516513; 17532041; 17589498; 17907802; 17916748; 17918257; 17922812; 17967422; 18219369; 18322228; 18435789; 18467591; 18510570; 18566389; 18606301; 18619508; 18632616; 18668547; 18676750; 18708368; 18718581; 18724005; 18751872; 18852899; 18996518; 19004987; 19008293; 19017797; 19196448; 19432671; 19443701; 19453261; 19561083; 19641137; 19711348; 19913121; 19926892; 19950360; 20237496; 20436471; 20452482; 20455868; 20485444; 20504948; 20628086; 20628624; 20673868; 20839008; 20839921; 20869948; 20925194; 21239715; 21481374; 21623375; 21717212; 21791433; 21854753; 21895511; 21938481; 21945122; 22028782; 22052465; 22082370; 22186992; 22365076; 22678116; 23061794; 23233531; 23251661; 23260168; 23285029; 23471483; 23520016; 23684409; 23688065; 23834954; 23924854; 24157873 colony stimulating factor 1 (macrophage) Ensembl:ENSG00000184371 HGNC:2432 HPRD:00388 MIM:120420 Vega:OTTHUMG00000011646 CSF1 Bin Zhao, Yue Liu, Oliver He CS-5 CSHP1 CSL hCS-L WEB: http://www.ncbi.nlm.nih.gov/gene CSHL1 chorionic somatomammotropin hormone-like 1 1444 17q24.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0005179 (EC: NAS, PMID: 2744760); GO_0005575 (EC: ND); GO_0005576 (EC: IEA); GO_0008150 (EC: ND); GO_0046872 (EC: IEA) PMID: 1378436; 1980158; 2744760; 3030680; 8083227; 12370315; 12477932; 19913121; 20628086 chorionic somatomammotropin hormone-like 1 Ensembl:ENSG00000204414 HGNC:2442 HPRD:04623 MIM:603515 Vega:OTTHUMG00000172287 CSHL1 Bin Zhao, Yue Liu, Oliver He CK1 CK1a CKIa HEL-S-77p HLCDGP1 PRO2975 WEB: http://www.ncbi.nlm.nih.gov/gene CSNK1A1 casein kinase 1, alpha 1 1452 5q32 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0000777 (EC: IEA); GO_0004672 (EC: TAS, PMID: 10777483); GO_0004674 (EC: IDA, PMID: 18305108); GO_0005515 (EC: IPI, PMID: 16511560); GO_0005524 (EC: IEA); GO_0005813 (EC: IDA); GO_0005829 (EC: TAS); GO_0005847 (EC: IDA, Qualifier: colocalizes_with, PMID: 18305108); GO_0006468 (EC: IDA, PMID: 18305108); GO_0007067 (EC: IEA); GO_0007165 (EC: NAS, PMID: 10777483); GO_0007166 (EC: TAS, PMID: 10777483); GO_0016055 (EC: IEA); GO_0016607 (EC: IDA, PMID: 18305108) PMID: 1409656; 7559483; 7622570; 7797465; 8050587; 8253806; 8404858; 8972483; 9045708; 9109395; 9360956; 9391750; 9630228; 9765199; 9771888; 10413673; 10617630; 10777483; 10930456; 10961987; 11278595; 11500362; 11583622; 11779193; 11875057; 11884395; 11955436; 12000790; 12062430; 12210746; 12477932; 12820959; 14558941; 14574644; 15003508; 15131121; 15327769; 15489334; 15557340; 15635413; 15687492; 15761153; 16024788; 16061179; 16344560; 16371461; 16511560; 16565220; 16616143; 16753179; 16880514; 16943283; 16959772; 17110929; 17192257; 17318175; 17626781; 17979178; 18067272; 18246126; 18305108; 18411282; 18590726; 18669630; 19050041; 19118383; 19185594; 19244247; 19322201; 19426738; 19531213; 19576224; 19738201; 19759023; 19797085; 19805514; 19875381; 19913121; 20348946; 20360068; 20551178; 20628086; 20647544; 20696773; 21139048; 21179498; 21382349; 21642993; 21890473; 21906983; 21925390; 21963094; 21985131; 21988832; 22017877; 22350414; 22505724; 22623428; 22824801; 22916255; 22939624; 22939629; 23000965; 23028042; 23148689; 23455922; 23580615; 24244405; 24250222 casein kinase 1, alpha 1 Ensembl:ENSG00000113712 HGNC:2451 HPRD:02739 MIM:600505 Vega:OTTHUMG00000163463 CSNK1A1 Bin Zhao, Yue Liu, Oliver He ARMD11 WEB: http://www.ncbi.nlm.nih.gov/gene CST3 cystatin C 1471 20p11.21 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0001540 (EC: IPI, PMID: 18026102); GO_0002020 (EC: IPI, PMID: 6203523); GO_0004866 (EC: IDA, PMID: 15127951); GO_0004869 (EC: IDA, PMID: 6203523); GO_0005515 (EC: IPI, PMID: 15127951); GO_0005576 (EC: IMP, PMID: 18026102); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 18613859); GO_0006952 (EC: IDA, PMID: 6203523); GO_0010466 (EC: IDA, PMID: 6203523); GO_0010703 (EC: IC, PMID: 7890620); GO_0010711 (EC: IEP, PMID: 10545518); GO_0010716 (EC: IEP, PMID: 10545518); GO_0010951 (EC: IDA, PMID: 15127951); GO_0034103 (EC: IEP, PMID: 10545518); GO_0043206 (EC: IGI, PMID: 18026102); GO_0060311 (EC: IMP, PMID: 10545518); GO_0060313 (EC: IEP, PMID: 10545518); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1352269; 1731767; 1996959; 2013314; 2304899; 2363674; 2541223; 2567273; 2689007; 2764935; 2900981; 3495457; 3517880; 6203523; 6283552; 6365094; 6662498; 7890620; 8083219; 8179826; 8486384; 10428479; 10545518; 10993992; 11074789; 11115496; 11276250; 11468325; 11681790; 11711204; 11750287; 11780052; 11815350; 11865157; 12038606; 12101112; 12477932; 12479412; 12483523; 12589965; 12663624; 12670666; 12738401; 12758063; 12787072; 12938144; 14503883; 14672279; 14714581; 14726415; 15013312; 15034766; 15037657; 15086483; 15122877; 15127951; 15174051; 15212828; 15223845; 15336605; 15340161; 15350470; 15479453; 15489334; 15603510; 15719405; 15728313; 15829557; 15832773; 15860739; 15882666; 16005452; 16049933; 16131730; 16170782; 16188386; 16213753; 16386559; 16437581; 16443201; 16446102; 16481598; 16608402; 16612982; 16612983; 16640527; 16713569; 16838182; 16979980; 17130480; 17192785; 17210589; 17310123; 17353786; 17394021; 17470433; 17537416; 17552057; 17636214; 17660266; 17668246; 17718592; 17728092; 17822797; 17826782; 17852800; 17852801; 17901710; 17903292; 17947596; 17963746; 17998865; 18026100; 18026102; 18044340; 18089366; 18187137; 18216060; 18280806; 18307033; 18314113; 18317874; 18319326; 18356552; 18373213; 18376131; 18408364; 18418694; 18454664; 18461289; 18496846; 18508448; 18511756; 18566660; 18594189; 18613859; 18667743; 18674527; 18703370; 18713542; 18804033; 18815241; 18824671; 18830724; 18949742; 18953178; 19056867; 19119287; 19137579; 19151417; 19252175; 19293566; 19357259; 19359536; 19394726; 19403428; 19419268; 19436062; 19446036; 19517296; 19523634; 19585181; 19597297; 19597298; 19601795; 19636441; 19674067; 19741512; 19765773; 19774637; 19808324; 19816197; 19819453; 19861863; 19915865; 19929276; 19938052; 20052346; 20132026; 20157249; 20175878; 20353367; 20383146; 20399428; 20413850; 20447660; 20450259; 20468060; 20482807; 20489688; 20502295; 20534741; 20538834; 20574650; 20576828; 20692472; 20699092; 20802417; 20806899; 20809110; 20849835; 20858959; 20879967; 20880607; 20882990; 20885369; 20921817; 20923994; 20926009; 20980977; 21051748; 21069389; 21094842; 21112096; 21115625; 21143385; 21151566; 21187262; 21198422; 21274315; 21286018; 21315176; 21388623; 21415918; 21470355; 21494031; 21518160; 21577020; 21617716; 21619490; 21697790; 21700821; 21710343; 21723753; 21740322; 21757984; 21782177; 21784814; 21795086; 21852668; 21861242; 21927796; 21928225; 22008011; 22057131; 22057374; 22072023; 22117908; 22139178; 22207347; 22209964; 22228436; 22267378; 22278599; 22287159; 22305809; 22307441; 22315498; 22315970; 22322818; 22349874; 22426688; 22467317; 22474211; 22515481; 22547045; 22622496; 22663994; 22669102; 22674847; 22705926; 22710694; 22809763; 22818840; 22837540; 22844527; 22898924; 22899766; 22947524; 22978689; 23008697; 23026591; 23026592; 23070277; 23089714; 23093662; 23095576; 23111743; 23142864; 23179198; 23194995; 23258794; 23300153; 23306163; 23335043; 23347458; 23383156; 23392363; 23396290; 23414098; 23414447; 23423253; 23429977; 23479071; 23518194; 23519666; 23530579; 23574755; 23594833; 23629649; 23629651; 23698027; 23698074; 23701892; 23706287; 23835667; 23836469; 23849305; 23852792; 24295505 cystatin C Ensembl:ENSG00000101439 HGNC:2475 HPRD:05056 MIM:604312 Vega:OTTHUMG00000032080 CST3 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene CTH cystathionase (cystathionine gamma-lyase) 1491 1p31.1 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000096 (EC: TAS); GO_0000098 (EC: TAS); GO_0004123 (EC: IDA, PMID: 10212249); GO_0004123 (EC: TAS); GO_0005515 (EC: IPI); GO_0005516 (EC: IEA); GO_0005634 (EC: IDA); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0006534 (EC: TAS, PMID: 1339280); GO_0016846 (EC: TAS); GO_0018272 (EC: IDA, PMID: 19019829); GO_0019344 (EC: IDA, PMID: 10212249); GO_0019344 (EC: IEA); GO_0019346 (EC: TAS); GO_0030170 (EC: IDA, PMID: 10212249); GO_0030968 (EC: TAS); GO_0034641 (EC: TAS); GO_0043066 (EC: IEA); GO_0043123 (EC: IEA); GO_0044281 (EC: TAS); GO_0044524 (EC: IMP); GO_0044540 (EC: IMP); GO_0047982 (EC: TAS); GO_0051092 (EC: IEA); GO_0051289 (EC: IPI, PMID: 19019829); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070814 (EC: IDA, PMID: 19019829); GO_0080146 (EC: TAS); GO_2001234 (EC: IEA) PMID: 1339280; 8125298; 10212249; 12477932; 12574942; 15151507; 15347670; 15489334; 16189514; 16710414; 17311259; 18029348; 18476726; 18676680; 18701025; 18849566; 18988749; 19019829; 19048631; 19056867; 19161160; 19170196; 19261609; 19322201; 19324355; 19418582; 19428278; 19531479; 19625176; 19692168; 19850743; 19913121; 19948975; 20175737; 20446008; 20584029; 20628086; 20634891; 20849728; 21139048; 21507721; 21659522; 21886822; 21890473; 21906983; 21963094; 21988832; 22034194; 22310774; 22360859; 22863883; 23393010; 23410520; 23704251; 24025145 cystathionase (cystathionine gamma-lyase) CTH Bin Zhao, Yue Liu, Oliver He CTNNB MRD19 armadillo WEB: http://www.ncbi.nlm.nih.gov/gene CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1499 OK/SW-cl.35 3p21 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000122 (EC: IBA); GO_0000578 (EC: IBA); GO_0000922 (EC: IEA); GO_0001102 (EC: IPI, PMID: 19443654); GO_0001569 (EC: IBA); GO_0001569 (EC: IC); GO_0001658 (EC: IBA); GO_0001701 (EC: IEA); GO_0001702 (EC: IBA); GO_0001708 (EC: IEA); GO_0001711 (EC: IBA); GO_0001764 (EC: IEA); GO_0001837 (EC: TAS, PMID: 14679171); GO_0001840 (EC: IEA); GO_0001889 (EC: IBA); GO_0002052 (EC: IEA); GO_0002053 (EC: IEA); GO_0002089 (EC: IEA); GO_0003136 (EC: IBA); GO_0003266 (EC: IEA); GO_0003337 (EC: IBA); GO_0003682 (EC: IEA); GO_0003690 (EC: IEA); GO_0003700 (EC: IEA); GO_0003713 (EC: IDA, PMID: 11751639); GO_0003713 (EC: IMP, PMID: 12949260); GO_0004871 (EC: NAS, PMID: 10192393); GO_0005198 (EC: IBA); GO_0005515 (EC: IPI, PMID: 10773885); GO_0005634 (EC: IDA, PMID: 10980594); GO_0005654 (EC: TAS); GO_0005667 (EC: IDA, PMID: 11751639); GO_0005737 (EC: IDA, PMID: 11793365); GO_0005813 (EC: IDA, PMID: 18086858); GO_0005829 (EC: IDA, PMID: 10980594); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA); GO_0005911 (EC: IDA, PMID: 19151727); GO_0005912 (EC: IDA, PMID: 16858403); GO_0005913 (EC: IDA, PMID: 10403777); GO_0005915 (EC: IBA); GO_0005916 (EC: IBA); GO_0005938 (EC: IDA, PMID: 19038973); GO_0006351 (EC: IEA); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0007016 (EC: IBA); GO_0007155 (EC: IMP, PMID: 19101069); GO_0007160 (EC: IBA); GO_0007398 (EC: IBA); GO_0007403 (EC: IBA); GO_0007494 (EC: IEA); GO_0008022 (EC: IPI, PMID: 10773885); GO_0008134 (EC: IPI); GO_0008134 (EC: TAS, PMID: 16344550); GO_0008285 (EC: IDA, PMID: 12970740); GO_0009898 (EC: IBA); GO_0009948 (EC: IEA); GO_0009950 (EC: IBA); GO_0009954 (EC: IBA); GO_0010909 (EC: IMP, PMID: 15853773); GO_0014010 (EC: IBA); GO_0016020 (EC: ISS); GO_0016055 (EC: IDA, PMID: 10644691); GO_0016323 (EC: IEA); GO_0016328 (EC: IDA, PMID: 12072559); GO_0016337 (EC: IMP, PMID: 18593713); GO_0016342 (EC: IDA, PMID: 18593713); GO_0019899 (EC: IPI, PMID: 18356165); GO_0019900 (EC: IPI, PMID: 8638126); GO_0019901 (EC: IBA); GO_0019903 (EC: IPI, PMID: 16574648); GO_0021819 (EC: IEA); GO_0022009 (EC: IBA); GO_0030018 (EC: IBA); GO_0030027 (EC: IBA); GO_0030054 (EC: IDA, PMID: 19038973); GO_0030054 (EC: TAS, PMID: 17047063); GO_0030057 (EC: IBA); GO_0030316 (EC: IEA); GO_0030326 (EC: IBA); GO_0030331 (EC: IPI, PMID: 15304487); GO_0030521 (EC: NAS, PMID: 15572661); GO_0030539 (EC: IBA); GO_0030877 (EC: IDA, PMID: 16188939); GO_0030902 (EC: IBA); GO_0030997 (EC: IDA, PMID: 18086858); GO_0031016 (EC: IBA); GO_0031069 (EC: IBA); GO_0031528 (EC: IBA); GO_0031641 (EC: IEA); GO_0032331 (EC: IBA); GO_0032355 (EC: IDA, PMID: 15304487); GO_0032403 (EC: IEA); GO_0032481 (EC: TAS); GO_0032993 (EC: IDA, PMID: 10825188); GO_0033077 (EC: IBA); GO_0033234 (EC: IDA); GO_0034097 (EC: IEA); GO_0034333 (EC: IMP); GO_0034394 (EC: IMP); GO_0034750 (EC: IEA); GO_0035050 (EC: IEA); GO_0035112 (EC: IEA); GO_0035115 (EC: IEA); GO_0035116 (EC: IEA); GO_0035255 (EC: IEA); GO_0035257 (EC: IPI, PMID: 12799378); GO_0035257 (EC: TAS, PMID: 16344550); GO_0035315 (EC: TAS, PMID: 19251162); GO_0036023 (EC: ISS); GO_0042129 (EC: IBA); GO_0042475 (EC: IBA); GO_0042493 (EC: IEP, PMID: 18291362); GO_0042692 (EC: TAS); GO_0042733 (EC: IEA); GO_0043065 (EC: IDA, PMID: 12970740); GO_0043123 (EC: IBA); GO_0043198 (EC: IBA); GO_0043410 (EC: IBA); GO_0043587 (EC: IBA); GO_0044212 (EC: IDA, PMID: 18193033); GO_0044325 (EC: IPI, PMID: 19996314); GO_0044334 (EC: IMP, PMID: 17072303); GO_0044336 (EC: IMP, PMID: 12154096); GO_0045087 (EC: TAS); GO_0045177 (EC: IEA); GO_0045202 (EC: IBA); GO_0045294 (EC: IPI, PMID: 7650039); GO_0045296 (EC: IPI, PMID: 12734196); GO_0045445 (EC: IEA); GO_0045453 (EC: IEA); GO_0045603 (EC: IEA); GO_0045669 (EC: IBA); GO_0045671 (EC: IBA); GO_0045743 (EC: IBA); GO_0045765 (EC: TAS, PMID: 18756595); GO_0045892 (EC: IMP, PMID: 19653274); GO_0045893 (EC: IDA, PMID: 12970740); GO_0045893 (EC: IMP, PMID: 12949260); GO_0045944 (EC: IDA, PMID: 11751639); GO_0045944 (EC: IMP, PMID: 15592430); GO_0046332 (EC: IPI, PMID: 18593713); GO_0046686 (EC: IEA); GO_0048145 (EC: TAS, PMID: 16858403); GO_0048262 (EC: IBA); GO_0048469 (EC: IEA); GO_0048471 (EC: IDA, PMID: 19038973); GO_0048489 (EC: IBA); GO_0048538 (EC: IBA); GO_0048599 (EC: IBA); GO_0048617 (EC: IBA); GO_0048660 (EC: IMP, PMID: 17122440); GO_0048715 (EC: IEA); GO_0050681 (EC: NAS, PMID: 15572661); GO_0050808 (EC: IBA); GO_0051145 (EC: IBA); GO_0051149 (EC: TAS); GO_0051291 (EC: IEA); GO_0060066 (EC: IEA); GO_0060070 (EC: IDA, PMID: 12937339); GO_0060440 (EC: IBA); GO_0060441 (EC: IEA); GO_0060479 (EC: IBA); GO_0060484 (EC: IBA); GO_0060492 (EC: IBA); GO_0060742 (EC: IEA); GO_0060769 (EC: IBA); GO_0060789 (EC: IBA); GO_0060916 (EC: IBA); GO_0061047 (EC: IBA); GO_0061154 (EC: IMP); GO_0061198 (EC: IEA); GO_0061324 (EC: ISS); GO_0070062 (EC: IDA, PMID: 19199708); GO_0070369 (EC: IDA, PMID: 9065401); GO_0070411 (EC: IPI, PMID: 18593713); GO_0070412 (EC: IPI); GO_0070491 (EC: IEA); GO_0070602 (EC: IMP); GO_0071260 (EC: IEA); GO_0071363 (EC: IMP, PMID: 16858403); GO_0071681 (EC: IDA, PMID: 10868478); GO_0071944 (EC: IDA, PMID: 19038973); GO_0072033 (EC: IBA); GO_0072053 (EC: IBA); GO_0072054 (EC: IBA); GO_0072079 (EC: IBA); GO_0072182 (EC: ISS); GO_0090279 (EC: IDA, PMID: 19996314); GO_2000008 (EC: IDA, PMID: 19996314); GO_2000017 (EC: IEA); GO_2001234 (EC: IEA) PMID: 7542250; 7642713; 7650039; 7702605; 7706414; 7736793; 7806582; 7829088; 7876318; 7890674; 7954478; 8227214; 8259519; 8638126; 8663237; 8757136; 8838805; 9054423; 9065401; 9065402; 9110993; 9139698; 9214391; 9233779; 9245795; 9286858; 9294210; 9312064; 9348292; 9405455; 9419974; 9434630; 9482734; 9500465; 9512503; 9521872; 9535896; 9545347; 9566905; 9601641; 9632714; 9734785; 9738936; 9751710; 9762469; 9819408; 9823329; 9843967; 9852041; 9927029; 9971746; 9990852; 10021369; 10023660; 10026156; 10029089; 10037471; 10074433; 10092585; 10187801; 10192393; 10207020; 10228155; 10321728; 10330181; 10330403; 10341227; 10381631; 10391090; 10398436; 10403777; 10435629; 10462524; 10477752; 10488109; 10491393; 10545404; 10620020; 10635315; 10644691; 10655994; 10666372; 10679188; 10681592; 10706604; 10713156; 10748026; 10753743; 10769211; 10772923; 10773885; 10801826; 10806215; 10816572; 10825188; 10837025; 10861224; 10862698; 10868478; 10873669; 10890911; 10896949; 10898789; 10910767; 10947987; 10951583; 10958684; 10966653; 10980594; 10980707; 10987273; 11035789; 11050151; 11080149; 11080158; 11113628; 11136230; 11136974; 11152665; 11157977; 11166179; 11168528; 11179419; 11226248; 11245482; 11251183; 11254878; 11266540; 11274246; 11279024; 11309300; 11348595; 11389839; 11389840; 11401320; 11483589; 11526121; 11527961; 11532957; 11533658; 11590244; 11703283; 11707392; 11712088; 11713475; 11713476; 11716761; 11734550; 11744694; 11747475; 11751639; 11790773; 11792709; 11793365; 11795941; 11818547; 11819825; 11821434; 11826105; 11831984; 11834740; 11835406; 11836379; 11836555; 11839663; 11856748; 11857309; 11877440; 11889072; 11893906; 11916967; 11920497; 11921277; 11929826; 11930117; 11939410; 11940574; 11950845; 11953860; 11955436; 11955446; 11957146; 11960376; 11967263; 11972058; 11973335; 11983685; 12000714; 12000790; 12003790; 12019147; 12027456; 12037680; 12045208; 12051714; 12052822; 12060769; 12061792; 12070348; 12072559; 12077367; 12095414; 12107263; 12111402; 12114015; 12124804; 12127563; 12130512; 12151522; 12154096; 12169098; 12183361; 12189238; 12209953; 12209999; 12219004; 12235125; 12297048; 12297051; 12297840; 12370829; 12377785; 12384561; 12389996; 12398896; 12408824; 12408825; 12413882; 12417602; 12420223; 12421363; 12432063; 12438242; 12446675; 12452049; 12464179; 12466281; 12477932; 12478897; 12482967; 12501215; 12515622; 12531901; 12532436; 12532469; 12554773; 12556497; 12556519; 12571228; 12575848; 12587534; 12588987; 12589056; 12592400; 12603528; 12604612; 12606575; 12606944; 12618757; 12628243; 12634428; 12639940; 12640114; 12657632; 12657639; 12679314; 12692418; 12694354; 12695331; 12700239; 12708483; 12712206; 12727872; 12729800; 12734196; 12737446; 12748295; 12750561; 12771132; 12799378; 12800191; 12805222; 12808048; 12810642; 12820959; 12821935; 12824925; 12830000; 12839684; 12857869; 12861022; 12874278; 12883680; 12907143; 12917489; 12920240; 12927518; 12937339; 12944908; 12949260; 12952940; 12969793; 12970740; 12972427; 14516475; 14520463; 14561767; 14563838; 14567991; 14593076; 14595118; 14600025; 14625392; 14633602; 14637149; 14660579; 14679171; 14702039; 14706341; 14706645; 14742711; 14766232; 14960280; 14977843; 14985333; 14993280; 15003504; 15023525; 15060161; 15064706; 15077166; 15082903; 15102686; 15110721; 15111320; 15123239; 15126105; 15138556; 15149841; 15158448; 15163629; 15190077; 15194432; 15215241; 15221004; 15231748; 15239100; 15254684; 15256534; 15279902; 15289833; 15294866; 15304487; 15327767; 15327768; 15327769; 15331612; 15355978; 15381698; 15381903; 15455387; 15489334; 15492040; 15492215; 15500294; 15514031; 15520370; 15523694; 15525529; 15542433; 15557107; 15572661; 15572674; 15574752; 15588985; 15591320; 15592430; 15654359; 15660698; 15665104; 15668893; 15670774; 15684397; 15694380; 15695815; 15696778; 15698401; 15728254; 15729346; 15735679; 15735746; 15737630; 15768032; 15781969; 15782138; 15790758; 15791567; 15806138; 15811349; 15817486; 15829968; 15829978; 15832407; 15837931; 15843474; 15853773; 15888491; 15896469; 15899904; 15905404; 15916880; 15923648; 15927956; 15958533; 15972952; 15987741; 16007074; 16012954; 16014379; 16038041; 16039586; 16082250; 16084063; 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17129455; 17143299; 17160944; 17168211; 17172473; 17203186; 17208333; 17219201; 17220478; 17220880; 17229887; 17240357; 17241872; 17242406; 17259169; 17283121; 17283138; 17284619; 17289029; 17341890; 17353931; 17360711; 17383052; 17393110; 17393422; 17412698; 17429067; 17454753; 17466258; 17487982; 17502350; 17504383; 17505512; 17507638; 17510365; 17510384; 17513457; 17522055; 17526942; 17551084; 17558858; 17576040; 17579030; 17592150; 17595165; 17601350; 17601559; 17621269; 17637758; 17638895; 17641414; 17663505; 17668445; 17673525; 17676996; 17679465; 17693578; 17710160; 17721184; 17724465; 17764657; 17785436; 17851558; 17852416; 17854061; 17854394; 17875931; 17903198; 17905526; 17908501; 17914096; 17927853; 17927863; 17927878; 17949810; 17950943; 17952864; 17954973; 17956661; 17956664; 17962810; 17976063; 17977597; 17979146; 17979184; 17982235; 17983802; 17983804; 17992121; 17996206; 18006828; 18006853; 18008331; 18029348; 18044981; 18048388; 18059161; 18059173; 18077326; 18078131; 18078366; 18086858; 18087039; 18161931; 18165946; 18193033; 18199649; 18206728; 18215130; 18218837; 18223684; 18223693; 18242184; 18256147; 18258596; 18276111; 18281465; 18282277; 18284543; 18285264; 18287330; 18288545; 18291362; 18295959; 18296023; 18308950; 18309246; 18311776; 18313840; 18315906; 18316097; 18316596; 18320359; 18330089; 18330950; 18334222; 18335551; 18339854; 18347063; 18354482; 18356165; 18376386; 18378692; 18382662; 18384130; 18385740; 18391483; 18397460; 18419788; 18422699; 18439914; 18445113; 18445773; 18455580; 18456656; 18459111; 18460581; 18464243; 18466996; 18485479; 18486530; 18490349; 18490442; 18500270; 18515080; 18538736; 18540944; 18541010; 18552505; 18553167; 18560386; 18563180; 18566211; 18573912; 18579517; 18586027; 18591935; 18592156; 18593713; 18593907; 18593917; 18606139; 18609711; 18611862; 18615589; 18618575; 18619646; 18632669; 18632682; 18632848; 18636547; 18646694; 18647815; 18650423; 18653765; 18655368; 18667832; 18674869; 18676680; 18676739; 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19369584; 19372141; 19379556; 19383367; 19384065; 19389926; 19396152; 19401692; 19407222; 19413886; 19421142; 19423540; 19433865; 19435525; 19440933; 19443654; 19448414; 19448422; 19448592; 19453261; 19457867; 19461076; 19462446; 19475529; 19479054; 19481539; 19487278; 19492080; 19495794; 19498322; 19520846; 19526105; 19534622; 19536331; 19545383; 19556239; 19563778; 19576224; 19582367; 19607815; 19608668; 19609729; 19620634; 19625176; 19628668; 19633358; 19633924; 19635198; 19639172; 19644051; 19650189; 19651607; 19652203; 19653274; 19661031; 19661437; 19664078; 19667122; 19679059; 19679347; 19688824; 19690176; 19692168; 19693690; 19703516; 19703993; 19704056; 19706825; 19711366; 19726098; 19727391; 19728763; 19729480; 19745699; 19751190; 19755524; 19756656; 19777185; 19778269; 19780202; 19781444; 19784072; 19801982; 19810105; 19820688; 19826421; 19846673; 19850036; 19857041; 19887615; 19888426; 19898427; 19898734; 19900369; 19912361; 19913121; 19915524; 19923077; 19924227; 19931509; 19940019; 19941816; 19952356; 19956716; 19958059; 19961258; 19966299; 19966865; 19966869; 19967550; 19996288; 19996314; 20008139; 20012522; 20019092; 20020146; 20026641; 20028853; 20032304; 20033368; 20042714; 20056651; 20061390; 20074550; 20079187; 20086044; 20093106; 20096688; 20097766; 20112731; 20122174; 20123964; 20126258; 20126544; 20128690; 20129645; 20137080; 20143187; 20181957; 20193114; 20195621; 20197769; 20208143; 20210255; 20215423; 20224040; 20227366; 20232357; 20233054; 20236250; 20236666; 20302655; 20332102; 20332116; 20347502; 20348951; 20367250; 20369480; 20372837; 20395444; 20399743; 20406964; 20409609; 20412773; 20419129; 20428811; 20438785; 20439735; 20446815; 20454507; 20459822; 20460486; 20474081; 20491588; 20503246; 20505989; 20508033; 20514474; 20519433; 20519507; 20527231; 20529814; 20529828; 20531388; 20532534; 20533307; 20544848; 20550535; 20561405; 20571128; 20572881; 20580720; 20581239; 20589835; 20596253; 20596624; 20603076; 20603606; 20613673; 20615089; 20625999; 20628086; 20631314; 20631633; 20634891; 20639865; 20644561; 20646434; 20646651; 20660612; 20679491; 20693983; 20696077; 20705583; 20717765; 20736306; 20813688; 20818428; 20837771; 20840015; 20840677; 20840813; 20840866; 20856206; 20862283; 20870744; 20874444; 20886225; 20933443; 20937153; 20937768; 20943078; 20950152; 20959480; 20963515; 20972266; 20974860; 21030215; 21031436; 21047397; 21050342; 21056029; 21057570; 21061181; 21073496; 21076461; 21080917; 21084400; 21108734; 21115917; 21118991; 21122409; 21139048; 21145461; 21151392; 21165564; 21173432; 21179427; 21189258; 21195420; 21196339; 21207157; 21215703; 21225227; 21239045; 21240516; 21254927; 21259057; 21284870; 21292023; 21297666; 21297984; 21299429; 21299609; 21303971; 21317931; 21323417; 21325624; 21331989; 21336184; 21344156; 21350711; 21352379; 21354309; 21355306; 21357396; 21362399; 21368895; 21369691; 21378377; 21383695; 21384147; 21385933; 21391741; 21411632; 21422242; 21447180; 21448924; 21454805; 21457159; 21466614; 21479203; 21494638; 21502434; 21505183; 21506126; 21521850; 21524889; 21527747; 21531001; 21532622; 21538055; 21545903; 21562161; 21565795; 21569306; 21575861; 21577209; 21584489; 21602666; 21610149; 21612684; 21613219; 21617231; 21622533; 21625458; 21638320; 21643019; 21649463; 21661417; 21664290; 21665151; 21670201; 21671177; 21677537; 21678082; 21691299; 21704588; 21726809; 21743491; 21744004; 21747169; 21757651; 21761366; 21764279; 21769465; 21775056; 21781302; 21781452; 21781455; 21792768; 21803632; 21807967; 21821917; 21822311; 21822615; 21832049; 21836063; 21841793; 21849806; 21852086; 21852538; 21858114; 21858154; 21860425; 21875946; 21880956; 21881488; 21881870; 21884207; 21884214; 21890473; 21894439; 21901162; 21906983; 21908588; 21928230; 21935866; 21949247; 21949397; 21952639; 21963094; 21963849; 21965288; 21975680; 21980461; 21986938; 21987572; 21992464; 21993766; 21994129; 21999200; 22007144; 22014042; 22014044; 22017875; 22020335; 22022540; 22023520; 22024040; 22028615; 22034877; 22041457; 22049531; 22053859; 22053931; 22056988; 22080244; 22080605; 22081130; 22083140; 22083958; 22086512; 22093097; 22095489; 22095947; 22099930; 22100495; 22110128; 22110662; 22115830; 22126602; 22133004; 22135721; 22139084; 22142772; 22152854; 22154485; 22155184; 22156527; 22158051; 22158061; 22166221; 22174153; 22180573; 22187462; 22194818; 22198706; 22199277; 22202456; 22209340; 22211293; 22213192; 22221700; 22230368; 22231735; 22232518; 22234184; 22234612; 22241478; 22246236; 22276175; 22281980; 22287118; 22298898; 22298956; 22300273; 22303878; 22304920; 22307379; 22328737; 22333550; 22337891; 22350414; 22369945; 22372443; 22383975; 22391162; 22392736; 22392999; 22406377; 22407433; 22415718; 22425263; 22427053; 22438981; 22454041; 22455883; 22456437; 22458737; 22459450; 22460269; 22466651; 22469663; 22475572; 22494971; 22504420; 22505738; 22507326; 22509309; 22509369; 22516360; 22524844; 22526905; 22535304; 22540002; 22544606; 22550094; 22560296; 22576020; 22576689; 22579815; 22609776; 22613727; 22613765; 22614067; 22622416; 22630347; 22647378; 22653977; 22665063; 22668871; 22674979; 22682247; 22685558; 22692453; 22699938; 22702043; 22704062; 22705350; 22713211; 22715382; 22721621; 22723415; 22728435; 22730322; 22734943; 22739727; 22751121; 22766303; 22766794; 22773696; 22777005; 22800756; 22805760; 22815287; 22823957; 22848100; 22855334; 22864797; 22865883; 22905262; 22908324; 22912335; 22914623; 22915253; 22918686; 22919265; 22938416; 22944692; 22945641; 22946055; 22952611; 22955108; 22956765; 22958082; 23009572; 23020601; 23029025; 23030478; 23032819; 23042269; 23056515; 23065461; 23067217; 23068095; 23068607; 23086933; 23094073; 23099107; 23114888; 23117548; 23138978; 23142810; 23152409; 23159080; 23168683; 23174221; 23208497; 23211630; 23216017; 23220849; 23221384; 23222438; 23233089; 23235344; 23240619; 23243000; 23243217; 23245941; 23246962; 23252868; 23261982; 23268410; 23269799; 23273980; 23274133; 23275444; 23280187; 23292837; 23295859; 23301872; 23302090; 23307470; 23316072; 23317545; 23321667; 23325790; 23333633; 23337059; 23339186; 23349466; 23349811; 23355201; 23375645; 23405266; 23409032; 23437103; 23447569; 23452984; 23483729; 23489693; 23490077; 23499736; 23516071; 23516639; 23525311; 23539445; 23559415; 23559584; 23576562; 23578392; 23582741; 23583404; 23583669; 23592333; 23598517; 23602568; 23603171; 23613467; 23629955; 23640056; 23661344; 23667531; 23671189; 23671587; 23677639; 23690607; 23691015; 23704310; 23707389; 23717499; 23718855; 23727580; 23743566; 23744067; 23767917; 23784889; 23785285; 23787212; 23790492; 23796566; 23811937; 23826417; 23836524; 23840677; 23840886; 23844214; 23844215; 23887712; 23900566; 23913621; 23936352; 23950177; 23954158; 23959799; 23967107; 23983127; 23999248; 24003087; 24011952; 24019458; 24021281; 24042437; 24055345; 24061522; 24071572; 24096034; 24123033; 24127488; 24129577; 24145651; 24157255; 24158438; 24182564; 24255178; 24261884; 24276407; 24317174; 24342833; 24355586; 24413733; 24449884; 24469040; 24501426 catenin (cadherin-associated protein), beta 1, 88kDa Ensembl:ENSG00000168036 HGNC:2514 HPRD:00286 MIM:116806 Vega:OTTHUMG00000131393 CTNNB1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene CTSS cathepsin S 1520 1q21 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001968 (EC: IPI); GO_0002224 (EC: TAS); GO_0002250 (EC: IEP, PMID: 15196205); GO_0002474 (EC: TAS); GO_0002480 (EC: TAS); GO_0004197 (EC: IDA); GO_0005518 (EC: IDA); GO_0005576 (EC: NAS, PMID: 14718574); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA); GO_0005764 (EC: IDA, PMID: 15196205); GO_0006508 (EC: TAS, PMID: 1373132); GO_0006955 (EC: TAS, PMID: 8157683); GO_0019882 (EC: TAS, PMID: 15196205); GO_0019886 (EC: TAS); GO_0022617 (EC: TAS); GO_0030198 (EC: TAS); GO_0030574 (EC: IDA); GO_0034769 (EC: IDA); GO_0036021 (EC: TAS); GO_0042590 (EC: TAS); GO_0043202 (EC: TAS); GO_0043231 (EC: IDA); GO_0043236 (EC: IDA); GO_0043394 (EC: IPI); GO_0045087 (EC: TAS); GO_0051603 (EC: IDA); GO_0097067 (EC: IEP) PMID: 1373132; 1377692; 2044774; 7575468; 7717452; 7890620; 8083219; 8157683; 8706894; 9076588; 9099979; 9143502; 9164868; 9524075; 9545324; 9548757; 9876921; 10395917; 10721671; 10852705; 11115496; 11134363; 11241311; 11435427; 11710834; 11856830; 11884425; 12164923; 12437117; 12477932; 12643447; 12742663; 12748383; 12819022; 14718574; 14966190; 15196205; 15489334; 16140306; 16338279; 16354158; 16394095; 16410454; 16550604; 16710414; 16825321; 16839849; 17075137; 17227755; 17601350; 17622942; 17878156; 18029348; 18410260; 18565099; 18957408; 18977241; 19101991; 19104823; 19336475; 19404922; 19487544; 19553543; 19593952; 19700239; 19849712; 19913121; 19939935; 20045715; 20164293; 20180636; 20356901; 20628086; 20880494; 20881085; 21038029; 21094118; 21112096; 21143385; 21223957; 21250859; 21315176; 21585286; 21756348; 21878432; 21896479; 21967108; 21989182; 22101325; 22365146; 22424724; 22571763; 22730330; 22761382; 22796222; 22844403; 22844527; 22923671; 22952693; 23362198; 23585552; 23707200; 23742758; 23747398; 24335416 cathepsin S CTSS Bin Zhao, Yue Liu, Oliver He ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM WEB: http://www.ncbi.nlm.nih.gov/gene CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1588 15q21.1 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0005506 (EC: IEA); GO_0005783 (EC: IDA); GO_0005789 (EC: TAS); GO_0006694 (EC: TAS, PMID: 2848247); GO_0006703 (EC: TAS); GO_0006805 (EC: TAS); GO_0008202 (EC: TAS); GO_0008209 (EC: IEA); GO_0009055 (EC: TAS, PMID: 2848247); GO_0016020 (EC: TAS, PMID: 2848247); GO_0016125 (EC: TAS); GO_0016712 (EC: TAS, PMID: 1371509); GO_0019825 (EC: TAS, PMID: 2848247); GO_0020037 (EC: IDA, PMID: 19129847); GO_0044281 (EC: TAS); GO_0060736 (EC: IEA); GO_0070330 (EC: IDA, PMID: 19129847) PMID: 1371509; 1472013; 1724289; 1825497; 2040633; 2171939; 2541021; 2691883; 2808431; 2848247; 2973313; 3018730; 3390233; 3653507; 3964273; 7690033; 8090165; 8117272; 8265607; 8477708; 8530621; 9177373; 9211678; 9696881; 10566648; 10837748; 11076863; 11140838; 11181459; 11216915; 11232039; 11256614; 11344237; 11469726; 11571725; 11595700; 11756225; 11826265; 11850203; 11850205; 11850206; 11850208; 11850209; 11850210; 11850219; 11850220; 11850221; 11850222; 11850224; 11850225; 11850230; 11850233; 11850235; 11897504; 11903314; 11904449; 11925378; 11927588; 11935306; 11997208; 12036913; 12053085; 12154211; 12160997; 12161013; 12161505; 12164325; 12204674; 12213901; 12351690; 12370109; 12385014; 12428207; 12451990; 12462076; 12462077; 12466340; 12477932; 12489562; 12517592; 12592380; 12602902; 12606587; 12618873; 12620480; 12639945; 12690088; 12705475; 12720534; 12734209; 12736278; 12759877; 12768436; 12788892; 12839940; 12843146; 12846271; 12864794; 12914527; 12917334; 12944421; 14508827; 14517714; 14580722; 14593077; 14602139; 14631363; 14634838; 14714492; 14715870; 14744739; 14747179; 14973387; 14981949; 14990865; 15046111; 15072827; 15072828; 15074077; 15079018; 15083376; 15083377; 15083380; 15083381; 15126575; 15128046; 15132727; 15177662; 15181061; 15183689; 15199113; 15207764; 15229337; 15241822; 15298966; 15319333; 15330195; 15358790; 15364411; 15449726; 15489336; 15582747; 15583024; 15613678; 15640252; 15668497; 15677755; 15688015; 15695318; 15748828; 15774541; 15788666; 15794932; 15800924; 15802318; 15840311; 15862960; 15862961; 15862962; 15955695; 16019206; 16020944; 16024248; 16039845; 16045239; 16086586; 16103457; 16128984; 16146740; 16199862; 16202920; 16213843; 16232327; 16244490; 16251630; 16251760; 16260521; 16269961; 16287071; 16302261; 16303757; 16306085; 16322405; 16344016; 16344560; 16381901; 16392624; 16395678; 16402077; 16406421; 16418790; 16424004; 16426763; 16467490; 16473000; 16498360; 16498361; 16498363; 16498364; 16541304; 16556483; 16566930; 16595205; 16604491; 16608396; 16621515; 16634644; 16641167; 16648498; 16684355; 16691199; 16723309; 16730930; 16733710; 16739881; 16741831; 16767510; 16782804; 16793950; 16798289; 16850246; 16875543; 16882736; 16894362; 16895991; 16896040; 16930994; 16949385; 16949391; 16964243; 16977255; 16997132; 17004113; 17065579; 17066438; 17118999; 17119036; 17158756; 17167982; 17176215; 17187946; 17216495; 17219197; 17325027; 17331471; 17336977; 17359589; 17372263; 17391072; 17400043; 17404019; 17405842; 17415442; 17482958; 17507620; 17507624; 17517397; 17562079; 17574328; 17584767; 17588204; 17589376; 17595315; 17615053; 17646720; 17657731; 17661084; 17662285; 17678915; 17681675; 17682677; 17687621; 17704407; 17766065; 17827443; 17893373; 17953943; 17962916; 17975727; 17979523; 17989043; 17989068; 18030614; 18048499; 18049890; 18083712; 18086758; 18157729; 18159088; 18163429; 18181018; 18182446; 18199708; 18201819; 18245543; 18274619; 18281655; 18299793; 18305346; 18426832; 18437511; 18445666; 18467089; 18483177; 18483761; 18491956; 18497059; 18501301; 18505907; 18510611; 18512790; 18559914; 18568448; 18593984; 18595017; 18601603; 18614276; 18614591; 18617186; 18622258; 18629629; 18636124; 18667686; 18676680; 18767927; 18817841; 18818748; 18820009; 18822378; 18847535; 18930188; 18941892; 18941913; 18955734; 18962445; 18980759; 19015200; 19019335; 19022561; 19064562; 19064572; 19064581; 19083124; 19093296; 19107851; 19116238; 19124504; 19124506; 19129847; 19137777; 19152063; 19158807; 19159688; 19170196; 19172223; 19174490; 19185610; 19194457; 19240151; 19282383; 19299445; 19324338; 19340622; 19366906; 19389254; 19415745; 19419293; 19438456; 19445691; 19453261; 19469636; 19470632; 19478482; 19491387; 19493871; 19500729; 19505920; 19514368; 19527514; 19549443; 19551860; 19555469; 19556341; 19558171; 19570444; 19573564; 19574343; 19589174; 19591804; 19598235; 19604497; 19625176; 19630952; 19639193; 19692168; 19776291; 19782135; 19789370; 19800002; 19800101; 19805543; 19808095; 19815003; 19818337; 19879925; 19883757; 19896534; 19906189; 19906814; 19913121; 19921206; 19933466; 19952760; 19956635; 19969081; 20004389; 20015405; 20026603; 20030115; 20048079; 20052540; 20053928; 20060879; 20064870; 20072949; 20133979; 20140262; 20144226; 20148360; 20164038; 20164294; 20173016; 20184498; 20186154; 20189936; 20193327; 20200332; 20211687; 20214802; 20231365; 20300828; 20305046; 20346360; 20351196; 20381444; 20385561; 20417295; 20430378; 20432167; 20453000; 20505544; 20526739; 20539301; 20546829; 20586553; 20588246; 20588308; 20628086; 20628746; 20634197; 20655525; 20668023; 20688833; 20716560; 20729390; 20734064; 20797716; 20819792; 20881004; 20881960; 20932310; 20937744; 20960227; 21125383; 21154336; 21170323; 21188138; 21198743; 21217768; 21251330; 21269619; 21282199; 21296134; 21300759; 21319151; 21319995; 21320735; 21356374; 21377485; 21392518; 21392519; 21392520; 21414724; 21479914; 21511357; 21622727; 21676395; 21757507; 21771722; 21807013; 21939764; 21948762; 21952832; 21972004; 22057025; 22079757; 22089263; 22104650; 22106445; 22119029; 22130322; 22160249; 22185650; 22217837; 22237979; 22300440; 22315456; 22320986; 22331461; 22335023; 22384274; 22407818; 22426781; 22448795; 22492871; 22508516; 22511967; 22578533; 22633539; 22634420; 22638611; 22675492; 22731640; 22759564; 22773874; 22843875; 22848710; 22887836; 22889864; 22902617; 22915343; 22982181; 23001776; 23029457; 23085504; 23090135; 23110082; 23116507; 23122578; 23129173; 23178495; 23229009; 23239821; 23253631; 23340254; 23342035; 23350368; 23400010; 23438603; 23456168; 23461365; 23518928; 23540392; 23584792; 23599027; 23625281; 23635391; 23643682; 23661022; 23669293; 23700878; 23727336; 23729401; 23747729; 23748068; 23809139; 23846226; 23873111; 24049095 cytochrome P450, family 19, subfamily A, polypeptide 1 Ensembl:ENSG00000137869 HGNC:2594 HPRD:00488 MIM:107910 Vega:OTTHUMG00000131747 CYP19A1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 1600 RP6-239D12.2 1p32-p31 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0005829 (EC: IEA); GO_0005903 (EC: IEA); GO_0007162 (EC: IEA); GO_0007264 (EC: IEA); GO_0007494 (EC: IEA); GO_0007628 (EC: IEA); GO_0014069 (EC: IEA); GO_0016020 (EC: IEA); GO_0016358 (EC: IEA); GO_0021517 (EC: IEA); GO_0021589 (EC: IEA); GO_0021813 (EC: IEA); GO_0021942 (EC: IEA); GO_0042493 (EC: IEA); GO_0043005 (EC: IEA); GO_0043025 (EC: IEA); GO_0043548 (EC: IEA); GO_0045177 (EC: IEA); GO_0045666 (EC: IEA); GO_0045860 (EC: IEA); GO_0046426 (EC: IEA); GO_0048471 (EC: IEA); GO_0048712 (EC: IEA); GO_0050771 (EC: IEA); GO_0051645 (EC: IEA); GO_0097477 (EC: IEA) PMID: 9716537; 9790777; 9837937; 10373567; 10380922; 10460257; 10827173; 10959835; 11137154; 11279201; 11716507; 11812785; 11967127; 12077184; 12446734; 12477932; 12508107; 12581169; 12606711; 12646221; 12834112; 14578885; 14702039; 14961563; 15062102; 15175076; 15718228; 15883038; 16273093; 16481437; 16951405; 17062576; 17548821; 17974915; 18008369; 18076569; 18089558; 18519826; 19116273; 19853035; 19913121; 20041166; 20379614; 20568118; 20600896; 20628086; 21221998; 21315259; 21453247; 21832049; 22163036; 22394407; 22419519; 22610502; 22815893; 23333377; 23449627; 23568457 Dab, reelin signal transducer, homolog 1 (Drosophila) DAB1 Bin Zhao, Yue Liu, Oliver He DAPK WEB: http://www.ncbi.nlm.nih.gov/gene DAPK1 death-associated protein kinase 1 1612 9q21.33 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0004672 (EC: IDA, PMID: 7828849); GO_0004674 (EC: TAS, PMID: 16756490); GO_0004683 (EC: IDA, PMID: 10629061); GO_0005515 (EC: IPI, PMID: 15616583); GO_0005516 (EC: IDA, PMID: 10629061); GO_0005524 (EC: IDA, PMID: 10629061); GO_0005737 (EC: IEA); GO_0006468 (EC: IDA, PMID: 10629061); GO_0006468 (EC: TAS, PMID: 16756490); GO_0006915 (EC: IGI, PMID: 7828849); GO_0006915 (EC: IMP, PMID: 10629061); GO_0006915 (EC: TAS); GO_0008625 (EC: IEA); GO_0010506 (EC: TAS, PMID: 16756490); GO_0015629 (EC: IDA, PMID: 10629061); GO_0017148 (EC: IDA, PMID: 18995835); GO_0035556 (EC: IDA, PMID: 10629061); GO_0042802 (EC: IPI, PMID: 19180116); GO_0042981 (EC: IBA); GO_0042981 (EC: TAS, PMID: 16756490); GO_0043065 (EC: TAS); GO_0043066 (EC: IEA); GO_0046777 (EC: IDA, PMID: 10629061); GO_0046777 (EC: TAS, PMID: 16756490); GO_0071346 (EC: IDA, PMID: 18995835); GO_0097190 (EC: IMP, PMID: 7828849); GO_1902042 (EC: IEA); GO_2000310 (EC: ISS) PMID: 7828849; 8530096; 8889549; 10629061; 11485996; 11579085; 11809677; 12031912; 12082610; 12351649; 12370243; 12477932; 12708480; 12730201; 12792765; 12820391; 12911633; 14504087; 14530257; 14612952; 14767518; 15001356; 15018706; 15048887; 15146197; 15342556; 15492995; 15616583; 15634757; 15729359; 15809761; 16085644; 16132846; 16142356; 16213824; 16344560; 16756490; 16847012; 16858683; 16951219; 17056602; 17209433; 17244621; 17319784; 17324927; 17324930; 17339337; 17477876; 17523078; 17540169; 17592394; 17683884; 17690039; 17703233; 17868341; 17895359; 17953697; 18026971; 18195017; 18292548; 18336955; 18349282; 18422656; 18425396; 18519826; 18583991; 18799028; 18813964; 18830724; 18974095; 18995835; 19018866; 19094228; 19148529; 19180116; 19196380; 19212339; 19237746; 19259700; 19267229; 19272801; 19395874; 19506903; 19521987; 19627511; 19628771; 19695681; 19712061; 19778817; 19795445; 19878310; 19917631; 19957692; 20005690; 20018188; 20098747; 20103772; 20220139; 20360646; 20379614; 20389280; 20413850; 20471512; 20514412; 20534741; 20574532; 20630662; 20655775; 20677014; 20682398; 20704749; 20811724; 21115918; 21134130; 21139048; 21152427; 21152877; 21159370; 21167819; 21172653; 21176336; 21212658; 21287504; 21302620; 21311567; 21353277; 21497122; 21516484; 21725354; 21749573; 21797120; 21918973; 21922274; 21965790; 21979297; 22087225; 22095288; 22096027; 22116316; 22136354; 22160140; 22230750; 22293537; 22371043; 22420243; 22465880; 22490852; 22490855; 22549447; 22552543; 22610502; 22785394; 22827846; 22988864; 23175185; 23245584; 23275143; 23383130; 23438478; 23478405; 23545262; 23702034; 23800064; 23806751; 24314662 death-associated protein kinase 1 Ensembl:ENSG00000196730 HGNC:2674 HPRD:02902 MIM:600831 Vega:OTTHUMG00000020150 DAPK1 Bin Zhao, Yue Liu, Oliver He ACE1 CD143 DCP DCP1 ICH MVCD3 WEB: http://www.ncbi.nlm.nih.gov/gene ACE angiotensin I converting enzyme 1636 17q23.3 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0001822 (EC: IMP, PMID: 16116425); GO_0001974 (EC: IC, PMID: 1668266); GO_0002003 (EC: TAS); GO_0002005 (EC: IC, PMID: 1668266); GO_0002019 (EC: IC, PMID: 1668266); GO_0003081 (EC: IC, PMID: 1668266); GO_0003779 (EC: IDA, PMID: 16186248); GO_0004175 (EC: IDA, PMID: 15283675); GO_0004180 (EC: IEA); GO_0005515 (EC: IPI, PMID: 16186248); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 15283675); GO_0005768 (EC: IDA, PMID: 17077303); GO_0005886 (EC: IDA, PMID: 16186248); GO_0005886 (EC: TAS); GO_0008144 (EC: IDA, PMID: 1320019); GO_0008217 (EC: ISS); GO_0008237 (EC: IDA, PMID: 1320019); GO_0008237 (EC: ISS); GO_0008241 (EC: IDA, PMID: 1320019); GO_0008241 (EC: ISS, PMID: 11303049); GO_0008270 (EC: IDA, PMID: 12540854); GO_0009897 (EC: IDA, PMID: 9449382); GO_0014910 (EC: ISS); GO_0016021 (EC: IEA); GO_0019229 (EC: IC, PMID: 1668266); GO_0031404 (EC: IDA, PMID: 12540854); GO_0031711 (EC: IPI, PMID: 17077303); GO_0032943 (EC: IC, PMID: 7876104); GO_0042312 (EC: IC, PMID: 4322742); GO_0042447 (EC: IDA, PMID: 7876104); GO_0042447 (EC: ISS, PMID: 11303049); GO_0043171 (EC: IDA, PMID: 4322742); GO_0044267 (EC: TAS); GO_0050482 (EC: IDA, PMID: 17077303); GO_0060218 (EC: IC, PMID: 7876104); GO_0070062 (EC: IDA, PMID: 15326289) PMID: 1316930; 1320019; 1328889; 1338766; 1649623; 1668266; 2547653; 2554286; 2558109; 2849100; 4322742; 7876104; 7977726; 8131300; 8253769; 8541160; 8577943; 8755737; 9013598; 9449382; 9699903; 9916793; 10319862; 10391210; 10748135; 10769174; 10924499; 10969042; 11024215; 11027844; 11029323; 11030378; 11035682; 11036822; 11053482; 11054622; 11071585; 11076943; 11078932; 11079515; 11079661; 11082147; 11084577; 11085286; 11106322; 11106834; 11116112; 11116113; 11121171; 11122103; 11122322; 11124487; 11136175; 11137090; 11142763; 11155292; 11155741; 11168787; 11181802; 11200871; 11204304; 11208361; 11208365; 11208681; 11208755; 11210078; 11213892; 11217909; 11230288; 11231997; 11234416; 11239522; 11244007; 11248758; 11250978; 11256792; 11257269; 11265121; 11273991; 11280044; 11283791; 11286523; 11288810; 11289708; 11300226; 11303049; 11305733; 11311153; 11313676; 11317203; 11328206; 11330506; 11330874; 11341749; 11344227; 11345362; 11352521; 11354635; 11354780; 11354781; 11355019; 11357377; 11359065; 11361058; 11377823; 11381371; 11387483; 11399938; 11401071; 11401115; 11402126; 11408790; 11409168; 11421129; 11422735; 11427204; 11428725; 11431175; 11436125; 11436566; 11437027; 11446493; 11447495; 11459796; 11463587; 11473656; 11474225; 11484170; 11485372; 11485566; 11487079; 11498459; 11501342; 11505631; 11507973; 11509536; 11518842; 11522714; 11522715; 11525534; 11527624; 11531970; 11532108; 11544438; 11545752; 11568114; 11568784; 11569699; 11577832; 11593098; 11596779; 11599244; 11640993; 11665795; 11668351; 11677359; 11688760; 11691520; 11692002; 11696022; 11696658; 11696688; 11699055; 11707217; 11707686; 11711521; 11711524; 11712321; 11713104; 11714857; 11715070; 11718065; 11720769; 11723093; 11728946; 11732226; 11733623; 11737220; 11747437; 11749850; 11756350; 11768721; 11770799; 11773214; 11774217; 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22064901; 22081332; 22082670; 22086840; 22096122; 22099196; 22103580; 22136292; 22144991; 22147663; 22150532; 22151803; 22168210; 22173253; 22183487; 22198647; 22209668; 22214784; 22223701; 22239999; 22245237; 22247001; 22249557; 22264093; 22267728; 22271804; 22277253; 22277254; 22282502; 22307319; 22312901; 22325724; 22330210; 22333273; 22337243; 22339037; 22339243; 22345093; 22345095; 22348891; 22353325; 22380495; 22385293; 22387727; 22392877; 22392878; 22396489; 22405893; 22412018; 22420170; 22425118; 22450333; 22456784; 22480688; 22494836; 22513045; 22523556; 22538550; 22545216; 22554825; 22571796; 22576914; 22607040; 22644634; 22647781; 22648472; 22653650; 22667764; 22679279; 22683751; 22688325; 22693240; 22695028; 22719026; 22723835; 22729880; 22741763; 22745143; 22773337; 22776130; 22800767; 22808171; 22856224; 22874010; 22876137; 22876865; 22878841; 22884917; 22895845; 22938636; 22982912; 22983821; 22996021; 23000565; 23011259; 23030744; 23047907; 23049705; 23053304; 23054361; 23055331; 23056909; 23065219; 23065222; 23079706; 23084549; 23089703; 23090675; 23091417; 23122977; 23137230; 23142987; 23145508; 23151617; 23176367; 23179239; 23190598; 23208948; 23232975; 23235711; 23253410; 23270441; 23272666; 23278516; 23278772; 23281178; 23281417; 23289804; 23299466; 23305118; 23314967; 23317229; 23325447; 23358679; 23359027; 23362199; 23389097; 23391425; 23397151; 23398920; 23401650; 23409414; 23411129; 23413140; 23429214; 23444745; 23455487; 23458876; 23461768; 23469169; 23476055; 23480300; 23493435; 23505911; 23516848; 23540412; 23548421; 23560051; 23561051; 23566835; 23570557; 23603420; 23603844; 23615648; 23615722; 23621089; 23636094; 23650720; 23657604; 23660814; 23661020; 23661462; 23667908; 23691019; 23700157; 23702088; 23730990; 23739345; 23741507; 23745680; 23785786; 23786008; 23828384; 23846111; 23847294; 23860151; 23863317; 23876437; 23880184; 23973719; 23981749; 24003731; 24015270; 24055489; 24058088; 24076353; 24157068; 24168709; 24170657; 24297181; 24308214; 24505896; 24505959 angiotensin I converting enzyme Ensembl:ENSG00000159640 HGNC:2707 HPRD:00108 MIM:106180 Vega:OTTHUMG00000154927 ACE Bin Zhao, Yue Liu, Oliver He PSD95 SAP-90 SAP90 WEB: http://www.ncbi.nlm.nih.gov/gene DLG4 discs, large homolog 4 (Drosophila) 1742 17p13.1 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0002091 (EC: ISS); GO_0005515 (EC: IPI, PMID: 10433268); GO_0005737 (EC: ISS); GO_0005783 (EC: ISS); GO_0005886 (EC: ISS, Qualifier: colocalizes_with); GO_0005886 (EC: TAS); GO_0006461 (EC: IDA, PMID: 15496675); GO_0007165 (EC: TAS, PMID: 10364559); GO_0007204 (EC: ISS); GO_0007268 (EC: TAS); GO_0007399 (EC: TAS, PMID: 9286702); GO_0007411 (EC: TAS); GO_0007612 (EC: TAS, PMID: 9853749); GO_0008021 (EC: ISS); GO_0008022 (EC: IPI, PMID: 7477295); GO_0008328 (EC: ISS, Qualifier: colocalizes_with); GO_0014069 (EC: ISS); GO_0016188 (EC: ISS); GO_0019903 (EC: ISS); GO_0030054 (EC: ISS); GO_0030165 (EC: ISS); GO_0030666 (EC: TAS); GO_0030863 (EC: IDA, PMID: 12151521); GO_0031234 (EC: ISS); GO_0031697 (EC: ISS); GO_0031748 (EC: ISS); GO_0031812 (EC: ISS); GO_0032281 (EC: ISS); GO_0032403 (EC: ISS); GO_0032839 (EC: ISS); GO_0033130 (EC: ISS); GO_0035176 (EC: IEA); GO_0035255 (EC: ISS); GO_0035418 (EC: IDA, PMID: 15496675); GO_0035641 (EC: IEA); GO_0044224 (EC: ISS); GO_0044306 (EC: ISS); GO_0044309 (EC: ISS); GO_0045184 (EC: IDA, PMID: 15496675); GO_0045202 (EC: IDA, PMID: 15496675); GO_0045211 (EC: IDA, PMID: 12151521); GO_0048169 (EC: ISS); GO_0050806 (EC: ISS); GO_0050885 (EC: IEA); GO_0060076 (EC: ISS); GO_0060997 (EC: ISS); GO_0071625 (EC: IEA); GO_0097110 (EC: ISS); GO_0097113 (EC: ISS); GO_0097113 (EC: TAS, PMID: 19914352); GO_0097120 (EC: ISS); GO_0097481 (EC: ISS); GO_2000310 (EC: ISS); GO_2000463 (EC: ISS); GO_2000821 (EC: IEA) PMID: 7477295; 7569905; 8601796; 8615909; 8625413; 8665664; 8755482; 8938729; 9009191; 9024696; 9115257; 9148889; 9182804; 9278515; 9286702; 9286858; 9326658; 9430700; 9459447; 9481670; 9482110; 9502803; 9581761; 9581762; 9756850; 9786987; 9808460; 9853749; 9870942; 9892651; 10026200; 10207009; 10336672; 10341223; 10364559; 10373510; 10433268; 10488080; 10521598; 10527873; 10595517; 10627592; 10648730; 10725395; 10827173; 10839362; 10844022; 10859302; 10939335; 10958799; 10995758; 11029657; 11060025; 11134026; 11140673; 11152698; 11222640; 11274188; 11276111; 11279080; 11279111; 11319238; 11368788; 11440998; 11483650; 11502259; 11506858; 11526121; 11572861; 11679592; 11714708; 11723117; 11744724; 11805122; 11925566; 11937501; 11997254; 12006486; 12067714; 12068077; 12097473; 12151521; 12359873; 12390249; 12419528; 12435606; 12477932; 12531901; 12576483; 12586822; 12597860; 12609736; 12675619; 12682061; 12713445; 12738960; 12815021; 12860415; 12950712; 14622581; 14732708; 14760703; 14960569; 15024025; 15030493; 15317815; 15458844; 15494726; 15496675; 15603740; 15673434; 15978582; 16316992; 16332682; 16466689; 16473877; 16530958; 16637659; 16767099; 16828986; 16964398; 16990550; 16990791; 16990796; 17018285; 17093888; 17164261; 17360663; 17474147; 17474715; 17506933; 17672918; 17854350; 17916412; 18067320; 18308477; 18311135; 18424056; 18570704; 19017653; 19036954; 19118189; 19274064; 19322201; 19483657; 19726651; 19774677; 19913121; 19914352; 20201926; 20628086; 20921115; 21145461; 21151988; 21670103; 21726550; 21756874; 21849550; 21965656; 22001757; 22479202; 22673509; 22709448; 22745667; 22807451; 22809504; 22843680; 23260144; 23691031; 23782696; 23936182 discs, large homolog 4 (Drosophila) Ensembl:ENSG00000132535 HGNC:2903 HPRD:04199 MIM:602887 Vega:OTTHUMG00000134327 DLG4 Bin Zhao, Yue Liu, Oliver He CT154 DMT1 WEB: http://www.ncbi.nlm.nih.gov/gene DMRT1 doublesex and mab-3 related transcription factor 1 1761 9p24.3 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000122 (EC: ISS); GO_0000902 (EC: IEA); GO_0000987 (EC: ISS); GO_0002176 (EC: ISS); GO_0003700 (EC: IEA); GO_0005634 (EC: ISS); GO_0005737 (EC: IEA); GO_0006351 (EC: IEA); GO_0007283 (EC: IEA); GO_0007530 (EC: TAS, PMID: 10332030); GO_0008354 (EC: IEA); GO_0008584 (EC: TAS, PMID: 10332030); GO_0030238 (EC: ISS); GO_0035556 (EC: IEA); GO_0042803 (EC: IEA); GO_0045835 (EC: ISS); GO_0045840 (EC: ISS); GO_0045944 (EC: ISS); GO_0046661 (EC: ISS); GO_0046872 (EC: IEA); GO_0046982 (EC: IEA); GO_0048599 (EC: IEA); GO_0060008 (EC: ISS); GO_0060009 (EC: IEA); GO_0060903 (EC: IEA); GO_2000020 (EC: IEA) PMID: 9490411; 10332030; 10604464; 10857744; 10999792; 11040213; 11252745; 11329013; 12434333; 12477932; 15164053; 15489334; 16617334; 20007774; 20211142; 20379614; 20467438; 20543847; 20596660; 20685758; 21462105; 21551455; 21617256; 22573722; 22899867; 22939835; 23251661; 23303528; 23377640; 23555275; 23666239; 23666240 doublesex and mab-3 related transcription factor 1 Ensembl:ENSG00000137090 HGNC:2934 HPRD:03885 MIM:602424 Vega:OTTHUMG00000019435 DMRT1 Bin Zhao, Yue Liu, Oliver He CRMP-2 CRMP2 DHPRP2 DRP-2 DRP2 N2A3 ULIP-2 ULIP2 WEB: http://www.ncbi.nlm.nih.gov/gene DPYSL2 dihydropyrimidinase-like 2 1808 8p22-p21 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0001975 (EC: IEA); GO_0004157 (EC: TAS, PMID: 8973361); GO_0005515 (EC: IPI, PMID: 16260607); GO_0005739 (EC: IEA); GO_0005829 (EC: IDA); GO_0005829 (EC: TAS); GO_0005874 (EC: IDA, Qualifier: colocalizes_with); GO_0006139 (EC: TAS, PMID: 8973361); GO_0006208 (EC: IEA); GO_0006897 (EC: IMP); GO_0007010 (EC: ISS); GO_0007165 (EC: TAS, PMID: 8973361); GO_0007399 (EC: TAS, PMID: 8973361); GO_0007411 (EC: TAS); GO_0014049 (EC: IEA); GO_0016020 (EC: IDA, Qualifier: colocalizes_with); GO_0019901 (EC: IEA); GO_0021510 (EC: IEA); GO_0021772 (EC: IEA); GO_0030424 (EC: IEA); GO_0030425 (EC: IEA); GO_0030426 (EC: IEA); GO_0042220 (EC: IEA); GO_0042493 (EC: IEA); GO_0043025 (EC: IEA); GO_0045664 (EC: IEA); GO_0048489 (EC: IEA); GO_0070062 (EC: IDA) PMID: 7637782; 8125298; 8640231; 8973361; 10574455; 10757975; 10770920; 10818093; 10956643; 11121447; 11741937; 11771764; 12134159; 12477932; 12482610; 12942088; 12951196; 14702039; 15207709; 15342556; 15489334; 15652488; 15672539; 15858820; 16260607; 16321170; 16344560; 16380905; 16611631; 16964243; 17043677; 17229153; 17500595; 17683481; 18029348; 18203259; 18218617; 18460467; 18583979; 19110265; 19151921; 19235893; 19322201; 19328558; 19405953; 19519308; 19659462; 19666111; 20379614; 20381070; 20414250; 20801876; 21139048; 21271304; 21302347; 21319273; 21521879; 21565611; 21642979; 21694731; 21832084; 21860090; 21890473; 21900206; 21988832; 22227566; 22279220; 22431514; 22443207; 22586326; 22863883; 22954668; 23000965; 23023514; 23185275; 23836888; 24036111; 24133216; 24250222 dihydropyrimidinase-like 2 Ensembl:ENSG00000092964 HGNC:3014 HPRD:03914 MIM:602463 Vega:OTTHUMG00000099439 DPYSL2 Bin Zhao, Yue Liu, Oliver He CRMP-4 CRMP4 DRP-3 DRP3 LCRMP ULIP ULIP-1 WEB: http://www.ncbi.nlm.nih.gov/gene DPYSL3 dihydropyrimidinase-like 3 1809 5q32 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0005615 (EC: ISS); GO_0005829 (EC: ISS); GO_0005829 (EC: TAS); GO_0006208 (EC: IEA); GO_0007411 (EC: TAS); GO_0010976 (EC: ISS); GO_0010977 (EC: ISS); GO_0016812 (EC: IEA); GO_0017124 (EC: ISS); GO_0030027 (EC: ISS); GO_0030336 (EC: ISS); GO_0030426 (EC: ISS); GO_0031941 (EC: ISS); GO_0035374 (EC: ISS); GO_0044297 (EC: ISS); GO_0048678 (EC: ISS); GO_0051017 (EC: ISS); GO_0051219 (EC: IEA); GO_0051260 (EC: ISS); GO_0051491 (EC: ISS); GO_0051764 (EC: ISS); GO_0070382 (EC: ISS, Qualifier: colocalizes_with); GO_0071345 (EC: ISS) PMID: 1602151; 8973361; 9115293; 10664068; 10748015; 10956643; 11771764; 12134159; 12444086; 12477932; 12745088; 15345747; 15933812; 16611631; 17043677; 17081983; 18029348; 20379614; 20543870; 20804502; 20977846; 21044950; 21139048; 21179545; 21319273; 22863883; 23000965; 23568759; 24011394 dihydropyrimidinase-like 3 Ensembl:ENSG00000113657 HGNC:3015 HPRD:03104 MIM:601168 Vega:OTTHUMG00000163437 DPYSL3 Bin Zhao, Yue Liu, Oliver He DVL DVL1L1 DVL1P1 WEB: http://www.ncbi.nlm.nih.gov/gene DVL1 dishevelled segment polarity protein 1 1855 RP5-890O3.5 1p36 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001505 (EC: ISS); GO_0003674 (EC: ND); GO_0004871 (EC: IEA); GO_0005109 (EC: IPI, PMID: 19388021); GO_0005515 (EC: IPI, PMID: 10330181); GO_0005737 (EC: IEA); GO_0005829 (EC: IEA); GO_0005874 (EC: IBA); GO_0005938 (EC: IBA); GO_0006366 (EC: IDA, PMID: 11742073); GO_0006469 (EC: IDA, PMID: 10330181); GO_0007269 (EC: ISS); GO_0007411 (EC: IBA); GO_0007507 (EC: NAS, PMID: 8644734); GO_0007528 (EC: ISS); GO_0010976 (EC: IEA); GO_0016023 (EC: ISS); GO_0016055 (EC: IEA); GO_0016328 (EC: IDA, Qualifier: colocalizes_with); GO_0019899 (EC: IPI, PMID: 15454084); GO_0019901 (EC: IPI, PMID: 19643732); GO_0021915 (EC: IEP, PMID: 8817329); GO_0022007 (EC: IEA); GO_0030136 (EC: IBA); GO_0030177 (EC: IDA, PMID: 11113207); GO_0030424 (EC: IBA); GO_0030425 (EC: IBA); GO_0030426 (EC: IBA); GO_0031122 (EC: IEA); GO_0031410 (EC: IDA, PMID: 11113207); GO_0032091 (EC: IDA, PMID: 19643732); GO_0032436 (EC: IMP); GO_0034504 (EC: IMP, PMID: 10330181); GO_0035176 (EC: IEA); GO_0035372 (EC: IEA); GO_0035556 (EC: IEA); GO_0042802 (EC: IPI, PMID: 10330181); GO_0043025 (EC: IBA); GO_0043113 (EC: ISS); GO_0045202 (EC: IBA); GO_0045202 (EC: ISS); GO_0045893 (EC: IDA, PMID: 12805222); GO_0048365 (EC: IBA); GO_0048668 (EC: IBA); GO_0048675 (EC: IBA); GO_0048813 (EC: IBA); GO_0048813 (EC: ISS); GO_0050808 (EC: ISS); GO_0060026 (EC: IBA); GO_0060070 (EC: IDA, PMID: 11113207); GO_0060071 (EC: IDA, PMID: 12805222); GO_0060134 (EC: IEA); GO_0071340 (EC: IBA); GO_0090103 (EC: IBA); GO_0090179 (EC: IBA); GO_0090263 (EC: IEA) PMID: 8288125; 8644734; 8817329; 8856345; 9192851; 9344861; 9482734; 10330181; 10330403; 10332026; 10428961; 10581192; 10644691; 10806215; 11113207; 11487578; 11742073; 11779461; 11803455; 11818547; 12477932; 12490194; 12533515; 12556519; 12650946; 12805222; 12824876; 12883684; 12941796; 14684739; 14702039; 14747478; 14750955; 15262978; 15342556; 15454084; 15456783; 15852005; 16169070; 16457155; 16621789; 17593335; 18093802; 18162551; 18223681; 18347071; 18632848; 18692936; 18760999; 18976975; 19388021; 19453261; 19465938; 19561074; 19625296; 19643732; 19956716; 20177058; 20227366; 20388731; 20412773; 20439735; 20634891; 20639201; 20846493; 21044957; 21262972; 21900206; 21906983; 21963094; 21988832; 22467858; 22826439; 23836490 dishevelled segment polarity protein 1 Ensembl:ENSG00000107404 HGNC:3084 HPRD:03220 MIM:601365 Vega:OTTHUMG00000003069 DVL1 Bin Zhao, Yue Liu, Oliver He DYRK DYRK1 HP86 MNB MNBH MRD7 WEB: http://www.ncbi.nlm.nih.gov/gene DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1859 21q22.13 20140408 9606 21 protein-coding Official from a nomenclature committee GO_0000278 (EC: TAS); GO_0004672 (EC: TAS, PMID: 8769099); GO_0004674 (EC: ISS); GO_0004712 (EC: IEA); GO_0004713 (EC: ISS); GO_0004715 (EC: IDA, PMID: 9748265); GO_0005515 (EC: IPI, PMID: 14500717); GO_0005524 (EC: IEA); GO_0005634 (EC: ISS); GO_0005654 (EC: TAS); GO_0006468 (EC: ISS); GO_0007399 (EC: TAS, PMID: 8769099); GO_0007623 (EC: ISS); GO_0016607 (EC: ISS); GO_0018105 (EC: IEA); GO_0018107 (EC: ISS); GO_0018108 (EC: IDA, PMID: 9748265); GO_0018108 (EC: ISS); GO_0030529 (EC: IEA); GO_0043518 (EC: ISS); GO_0043621 (EC: ISS); GO_0046777 (EC: ISS); GO_0048156 (EC: ISS); GO_0090312 (EC: ISS) PMID: 8274451; 8769099; 8872470; 8975710; 9037601; 9048932; 9284911; 9503011; 9503019; 9748265; 9784410; 10329007; 10644696; 10830953; 11311120; 11877424; 12138125; 12477932; 12576186; 12799418; 12964950; 14500717; 14593110; 14623875; 15068245; 15068246; 15126119; 15324660; 15369779; 15592455; 15694837; 15778465; 15917294; 16009940; 16242644; 16512921; 16733250; 16919501; 16959772; 17135279; 17145134; 17192257; 17229891; 17294446; 17536841; 17906291; 18005339; 18231969; 18366763; 18405873; 18468476; 18509201; 18658135; 18678649; 18696092; 18729074; 18771760; 19016842; 19081073; 19242551; 19322201; 19383720; 19722700; 19801542; 19995442; 20167603; 20237271; 20456003; 20694148; 20696760; 20940704; 21102440; 21126318; 21135538; 21139048; 21156027; 21156028; 21157379; 21205194; 21215488; 21252229; 21294719; 21364930; 21498570; 21498571; 21637297; 21777625; 21832049; 21878370; 21890473; 21965663; 22110360; 22154664; 22269890; 22354171; 22495309; 22669612; 22765017; 22767602; 22792062; 22876196; 22990118; 23099646; 23124096; 23147510; 23360763; 23382691; 23455922; 23512985; 23602568; 23635774; 24119401 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Ensembl:ENSG00000157540 HGNC:3091 HPRD:09018 MIM:600855 Vega:OTTHUMG00000086657 DYRK1A Bin Zhao, Yue Liu, Oliver He ECE WEB: http://www.ncbi.nlm.nih.gov/gene ECE1 endothelin converting enzyme 1 1889 RP3-329E20.1 1p36.1 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001921 (EC: IMP, PMID: 18039931); GO_0003100 (EC: IC, PMID: 7805846); GO_0004175 (EC: IDA, PMID: 18039931); GO_0004222 (EC: ISS, PMID: 8062389); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005768 (EC: IDA, PMID: 18039931); GO_0005769 (EC: IDA, PMID: 18039931); GO_0005886 (EC: IDA, PMID: 18039931); GO_0007507 (EC: IMP, PMID: 9915973); GO_0009897 (EC: IDA, PMID: 9449382); GO_0010814 (EC: IDA, PMID: 18039931); GO_0010815 (EC: IDA, PMID: 18039931); GO_0010816 (EC: IDA, PMID: 18039931); GO_0016021 (EC: IDA, PMID: 7805846); GO_0016485 (EC: IDA, PMID: 7805846); GO_0016486 (EC: IDA, PMID: 7864876); GO_0017046 (EC: IC, PMID: 7864876); GO_0019229 (EC: IC, PMID: 7805846); GO_0031302 (EC: TAS, PMID: 18039931); GO_0031982 (EC: ISS, PMID: 9449382); GO_0033093 (EC: IDA, PMID: 9710124); GO_0034959 (EC: IDA, PMID: 7805846); GO_0042447 (EC: IDA, PMID: 7864876); GO_0042733 (EC: IMP, PMID: 9915973); GO_0042803 (EC: IPI, PMID: 7805846); GO_0043583 (EC: IMP, PMID: 9915973); GO_0046872 (EC: IEA); GO_0048471 (EC: IDA, PMID: 9710124); GO_0060037 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 7695628; 7805846; 7864876; 8062389; 8530372; 8641140; 8889548; 9253714; 9396733; 9449382; 9595387; 9710124; 9915973; 10438732; 10491078; 10620363; 10833511; 11723113; 11906289; 12011762; 12244060; 12393864; 12464614; 12477932; 12609744; 14597855; 15010576; 15126915; 15146197; 15240857; 15340356; 15342556; 15489334; 15665524; 16023075; 16234608; 16263699; 16289162; 16344560; 16526315; 16531800; 16567585; 16698938; 16710414; 16986361; 17081983; 17264805; 17295044; 17545092; 17592116; 17618613; 17664854; 17701914; 17712175; 17761169; 17897319; 17977716; 18029348; 18039931; 18334739; 18660489; 18781169; 18974277; 18992253; 19056867; 19222484; 19289136; 19531493; 19889475; 19913121; 20037208; 20301612; 20345647; 20346360; 20485444; 20538960; 20558134; 20628086; 20663017; 20725143; 21139048; 21554123; 21777246; 21851036; 21906983; 22027013; 22268729; 22322595; 22416137; 22693153; 22728136; 22731820; 22939629; 22972025; 23022525; 23175834; 23251661; 23283972 endothelin converting enzyme 1 Ensembl:ENSG00000117298 HGNC:3146 HPRD:02690 MIM:600423 Vega:OTTHUMG00000002625 ECE1 Bin Zhao, Yue Liu, Oliver He ARCND3 ET1 HDLCQ7 PPET1 QME WEB: http://www.ncbi.nlm.nih.gov/gene EDN1 endothelin 1 1906 6p24.1 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000122 (EC: IDA, PMID: 19767294); GO_0001516 (EC: IDA, PMID: 9492062); GO_0001569 (EC: IEA); GO_0001666 (EC: IEA); GO_0001701 (EC: IEA); GO_0001821 (EC: IEA); GO_0003100 (EC: IDA, PMID: 2649896); GO_0005125 (EC: IDA, PMID: 19767294); GO_0005179 (EC: IDA, PMID: 10770212); GO_0005515 (EC: IPI); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 10770212); GO_0005737 (EC: IDA, PMID: 12379507); GO_0006885 (EC: IEA); GO_0007166 (EC: IDA, PMID: 1713452); GO_0007186 (EC: IDA, PMID: 17078114); GO_0007204 (EC: IDA, PMID: 1917960); GO_0007205 (EC: IEA); GO_0007267 (EC: IDA, PMID: 12379507); GO_0007507 (EC: IEA); GO_0007585 (EC: IEA); GO_0007589 (EC: IEA); GO_0008284 (EC: IDA, PMID: 17078114); GO_0009953 (EC: IEA); GO_0010259 (EC: IEA); GO_0010460 (EC: IDA, PMID: 2649896); GO_0010595 (EC: TAS, PMID: 8999856); GO_0010613 (EC: IDA, PMID: 12847114); GO_0010870 (EC: IDA, PMID: 17178876); GO_0014032 (EC: IEA); GO_0014065 (EC: IDA, PMID: 17078114); GO_0014824 (EC: IDA, PMID: 8982507); GO_0014824 (EC: TAS, PMID: 1725334); GO_0014826 (EC: IDA, PMID: 9422810); GO_0015758 (EC: IEA); GO_0016049 (EC: IEA); GO_0019229 (EC: IEA); GO_0019233 (EC: IEA); GO_0019722 (EC: IDA, PMID: 10770212); GO_0030072 (EC: IDA, PMID: 10770212); GO_0030185 (EC: IDA, PMID: 16820593); GO_0030195 (EC: TAS, PMID: 16820593); GO_0030335 (EC: IDA, PMID: 9696419); GO_0030593 (EC: IDA, Qualifier: NOT, PMID: 9696419); GO_0030818 (EC: IEA); GO_0031583 (EC: IEA); GO_0031707 (EC: IDA, PMID: 10770212); GO_0031708 (EC: IDA, PMID: 10770212); GO_0032269 (EC: IDA, PMID: 19767294); GO_0032496 (EC: IEA); GO_0033574 (EC: IEA); GO_0034392 (EC: IEA); GO_0035094 (EC: IEA); GO_0035810 (EC: IEA); GO_0035815 (EC: IEA); GO_0042045 (EC: IEA); GO_0042310 (EC: IDA, PMID: 11410113); GO_0042313 (EC: IDA, PMID: 16820593); GO_0042474 (EC: IEA); GO_0042482 (EC: IEA); GO_0042554 (EC: IEA); GO_0043179 (EC: IEA); GO_0043200 (EC: IEA); GO_0043406 (EC: IDA, PMID: 10770212); GO_0043507 (EC: IDA, PMID: 12847114); GO_0045321 (EC: TAS, PMID: 16820593); GO_0045429 (EC: TAS, PMID: 8999856); GO_0045793 (EC: IDA, PMID: 12847114); GO_0045840 (EC: IDA, PMID: 10770212); GO_0045987 (EC: IEA); GO_0046887 (EC: IDA, PMID: 10770212); GO_0046888 (EC: IEA); GO_0048016 (EC: IDA, PMID: 1917960); GO_0048661 (EC: IDA, PMID: 10393673); GO_0051216 (EC: IEA); GO_0051482 (EC: IEA); GO_0051771 (EC: IDA, PMID: 16820593); GO_0051899 (EC: IEA); GO_0051930 (EC: IEA); GO_0060137 (EC: IEA); GO_0060298 (EC: IMP, PMID: 12847114); GO_0060585 (EC: IMP, PMID: 9492062); GO_0070101 (EC: IC, PMID: 17178876); GO_0071347 (EC: IEA); GO_0071356 (EC: IEA); GO_0090023 (EC: IEA) PMID: 1280264; 1422154; 1515112; 1713452; 1725334; 1736987; 1859417; 1864385; 1917960; 2005113; 2018043; 2201681; 2649896; 2659594; 2670930; 2678110; 3282927; 7509919; 7664037; 7773179; 8125160; 8144511; 8450044; 8482849; 8889548; 8982507; 8999856; 9257865; 9284755; 9324057; 9422810; 9453574; 9492062; 9595387; 9696419; 10220569; 10231710; 10334806; 10391210; 10393673; 10438732; 10620363; 10770212; 11179511; 11210078; 11399938; 11410113; 11448123; 11593097; 11601839; 11693192; 11742499; 11751711; 11795667; 11831453; 11858185; 11866544; 11932487; 11934840; 11991554; 11991733; 12009599; 12011762; 12013496; 12068797; 12077518; 12082592; 12087564; 12107733; 12117726; 12137974; 12144123; 12151765; 12189238; 12230494; 12379507; 12446192; 12459174; 12477932; 12508654; 12511547; 12529269; 12557940; 12565798; 12588850; 12620701; 12629276; 12657945; 12695528; 12721154; 12746758; 12750312; 12847114; 12855940; 12861161; 12887757; 12907686; 12941866; 12963677; 12972292; 13680553; 14514737; 14519635; 14523636; 14558091; 14574404; 14578413; 14587645; 14602502; 14634722; 14636060; 14639018; 14660616; 14685288; 14692644; 14733410; 14735061; 14736087; 14763917; 14769714; 15009217; 15041798; 15044479; 15047866; 15073116; 15093707; 15126915; 15139053; 15161426; 15188945; 15194301; 15198485; 15213100; 15224360; 15240857; 15269821; 15319532; 15347673; 15369130; 15466627; 15481145; 15489334; 15505112; 15518541; 15558022; 15568807; 15610525; 15621731; 15623376; 15643502; 15646831; 15652492; 15691296; 15699938; 15702240; 15743480; 15817494; 15818445; 15838269; 15838299; 15838323; 15838328; 15838333; 15838334; 15838336; 15838337; 15838340; 15838344; 15838351; 15838357; 15838368; 15838369; 15838370; 15864745; 15946241; 15946919; 15979050; 15988412; 16002759; 16021085; 16026642; 16076689; 16095497; 16097909; 16098041; 16169070; 16217751; 16234608; 16291872; 16320159; 16336267; 16357176; 16452160; 16466695; 16521405; 16526196; 16531800; 16582543; 16597412; 16648553; 16713569; 16720059; 16754659; 16769575; 16778329; 16809784; 16815566; 16820593; 16864942; 16931893; 16943682; 16947775; 16956834; 16971893; 16982943; 16986361; 17016610; 17016617; 17020466; 17078114; 17122448; 17123690; 17148661; 17178876; 17197385; 17203161; 17221318; 17222082; 17264805; 17274718; 17291632; 17328840; 17335511; 17340622; 17345061; 17353514; 17357073; 17357519; 17395629; 17404040; 17438153; 17444275; 17460393; 17470272; 17497038; 17497041; 17497362; 17505299; 17525706; 17535295; 17549358; 17556493; 17569300; 17575543; 17576235; 17664075; 17664854; 17681742; 17693542; 17701914; 17703412; 17850909; 17855483; 17875064; 17884295; 17893002; 17913962; 17938376; 17960156; 17967707; 17969585; 17996929; 18005077; 18023202; 18025413; 18031458; 18050250; 18063846; 18080871; 18212505; 18260253; 18288492; 18326921; 18346810; 18378042; 18379872; 18390205; 18395679; 18398338; 18401297; 18411415; 18436890; 18441204; 18442814; 18447854; 18463805; 18484695; 18489822; 18550016; 18568290; 18579320; 18579652; 18580062; 18603063; 18623111; 18660489; 18663623; 18676680; 18752143; 18764935; 18772174; 18794727; 18806884; 18809573; 18814847; 18822124; 18923236; 18945274; 18945538; 18953265; 18974277; 18991099; 18991188; 19012521; 19014602; 19046960; 19056482; 19057845; 19073831; 19074885; 19077312; 19086031; 19086263; 19087492; 19103606; 19116719; 19150882; 19170196; 19171135; 19188658; 19188660; 19212702; 19217622; 19225824; 19247692; 19254215; 19258923; 19264973; 19336370; 19358249; 19367425; 19369451; 19371341; 19391127; 19415232; 19416273; 19420105; 19446279; 19460784; 19475602; 19479828; 19520685; 19520754; 19526396; 19527488; 19536618; 19543207; 19558538; 19564455; 19578796; 19592490; 19625176; 19626996; 19634784; 19640695; 19661472; 19672034; 19687345; 19692168; 19717811; 19729965; 19730395; 19764340; 19767294; 19808370; 19862540; 19887561; 19899414; 19907721; 19913121; 19927348; 19948975; 19996987; 20015663; 20016521; 20028935; 20031624; 20051644; 20055532; 20055806; 20082271; 20083228; 20083432; 20091488; 20150570; 20188614; 20204072; 20217138; 20308035; 20339975; 20346360; 20368210; 20370579; 20416077; 20437399; 20452482; 20452970; 20485444; 20495015; 20497976; 20503287; 20537417; 20538124; 20538960; 20559285; 20562228; 20565774; 20572854; 20587610; 20588001; 20594474; 20594999; 20602615; 20608808; 20628086; 20628425; 20628428; 20634595; 20634796; 20634891; 20652766; 20663522; 20664700; 20670842; 20672350; 20673868; 20678167; 20685405; 20707291; 20725135; 20725137; 20725140; 20725141; 20725143; 20728421; 20837776; 20837906; 20873151; 20952631; 20952681; 20971496; 20974279; 21045115; 21059990; 21087804; 21129745; 21169360; 21174590; 21183790; 21208707; 21214096; 21217075; 21219832; 21251377; 21334758; 21356562; 21406182; 21418087; 21445967; 21490504; 21498707; 21498912; 21499502; 21515378; 21531894; 21557930; 21601190; 21637825; 21638248; 21656314; 21659661; 21666117; 21673044; 21677436; 21681744; 21701170; 21701423; 21712053; 21730058; 21741393; 21767690; 21773759; 21777246; 21786569; 21801587; 21801592; 21813388; 21826669; 21851036; 21896842; 21908890; 21932697; 21952518; 21959927; 22006997; 22045428; 22082020; 22113444; 22165675; 22175913; 22232246; 22265324; 22299030; 22321643; 22330820; 22341591; 22377253; 22406080; 22412088; 22415226; 22483689; 22483692; 22503784; 22504006; 22520393; 22525370; 22527528; 22545467; 22552325; 22553998; 22569256; 22580289; 22666926; 22675930; 22727793; 22759779; 22770822; 22796455; 22856221; 22856224; 22869459; 22907118; 22960172; 22965194; 22971991; 22994522; 23002189; 23018104; 23103494; 23142694; 23163519; 23208497; 23227981; 23233754; 23255664; 23273644; 23290569; 23329136; 23344160; 23372172; 23381795; 23401650; 23436272; 23436727; 23457411; 23523690; 23565184; 23643051; 23683481; 23713736; 23720837; 23815989; 23828677; 23832707; 23887640; 23902937; 24015303; 24056654; 24088894; 24184161; 24196534; 24268655 endothelin 1 Ensembl:ENSG00000078401 HGNC:3176 HPRD:07030 MIM:131240 Vega:OTTHUMG00000014266 EDN1 Bin Zhao, Yue Liu, Oliver He HOMG4 URG WEB: http://www.ncbi.nlm.nih.gov/gene EGF epidermal growth factor 1950 4q25 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0000186 (EC: IEA); GO_0001525 (EC: IDA, PMID: 15611079); GO_0002576 (EC: TAS); GO_0005154 (EC: TAS, PMID: 15611079); GO_0005509 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12297050); GO_0005576 (EC: IC, PMID: 9712850); GO_0005576 (EC: TAS); GO_0005615 (EC: IEA); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005886 (EC: IEA); GO_0006260 (EC: TAS, PMID: 9482941); GO_0007165 (EC: TAS); GO_0007171 (EC: TAS, PMID: 9712850); GO_0007173 (EC: TAS); GO_0007262 (EC: ISS); GO_0007596 (EC: TAS); GO_0008083 (EC: IDA, PMID: 15611079); GO_0008284 (EC: IDA, PMID: 15611079); GO_0008543 (EC: TAS); GO_0010800 (EC: IDA, PMID: 16314496); GO_0016021 (EC: IEA); GO_0018108 (EC: IEA); GO_0021940 (EC: IEA); GO_0030168 (EC: TAS); GO_0030297 (EC: TAS, PMID: 9712850); GO_0031093 (EC: TAS); GO_0035413 (EC: IDA); GO_0038095 (EC: TAS); GO_0042059 (EC: TAS); GO_0042327 (EC: IDA, PMID: 15611079); GO_0043388 (EC: ISS); GO_0043406 (EC: IDA, PMID: 15611079); GO_0045087 (EC: TAS); GO_0045741 (EC: IDA, PMID: 15611079); GO_0045741 (EC: TAS, PMID: 9712850); GO_0045840 (EC: IDA, PMID: 15611079); GO_0045893 (EC: IDA, PMID: 16314496); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0048754 (EC: IEA); GO_0051048 (EC: IDA, PMID: 10559227); GO_0060749 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070371 (EC: IDA, PMID: 16314496); GO_0090279 (EC: IDA, PMID: 19996314); GO_0090370 (EC: IEA); GO_1900127 (EC: IDA, PMID: 17324121); GO_2000008 (EC: IDA, PMID: 19996314); GO_2000060 (EC: IEA) PMID: 300079; 1281549; 1334406; 1501243; 1522591; 1639032; 2789514; 2790960; 3486749; 3491360; 6290982; 6382023; 6603475; 7540053; 7558411; 7615511; 7640657; 7730382; 7736574; 8077234; 8123596; 8413296; 8419140; 8639530; 8796265; 8845374; 9188692; 9356464; 9482941; 9544989; 9661876; 9687510; 9712850; 9925763; 10085134; 10199559; 10436156; 10559227; 10567358; 10579352; 10648629; 10734310; 10748174; 10788520; 10913131; 10973965; 11438527; 11751923; 11786904; 11796824; 11823423; 11844511; 11894095; 11896055; 11903419; 11914075; 11925427; 11950840; 11971908; 11994282; 12009575; 12093292; 12138086; 12141529; 12163055; 12163506; 12192610; 12202942; 12218189; 12297050; 12368284; 12388817; 12397374; 12425525; 12477932; 12508124; 12531699; 12540376; 12593796; 12620237; 12637502; 12643788; 12667326; 12672817; 12722480; 12768436; 12788694; 12795334; 12879019; 12954631; 12960147; 14507446; 14520709; 14523024; 14560030; 14614718; 14651960; 14662770; 14665621; 14676838; 15003992; 15063762; 15081423; 15087376; 15129177; 15175028; 15180992; 15183666; 15192046; 15194442; 15252009; 15256384; 15260478; 15272014; 15329330; 15373781; 15373782; 15373802; 15475003; 15481560; 15485655; 15485674; 15488707; 15489334; 15491342; 15509542; 15536154; 15574420; 15611079; 15613483; 15620700; 15622242; 15659382; 15663953; 15675968; 15729146; 15735691; 15748906; 15798095; 15802268; 15837620; 15860930; 15886816; 15901830; 15913871; 15950078; 15950906; 15962011; 15982634; 16019439; 16033767; 16115648; 16134968; 16210470; 16214932; 16248985; 16274239; 16274250; 16282324; 16314496; 16316319; 16332692; 16344560; 16407418; 16407834; 16413767; 16428382; 16436184; 16584205; 16636672; 16691190; 16728406; 16762922; 16788380; 16820871; 16837648; 16847055; 16872636; 16885506; 16939220; 16946702; 16969495; 16979250; 17123472; 17175377; 17204151; 17223314; 17227756; 17311928; 17316357; 17324121; 17334773; 17392355; 17397984; 17433039; 17453000; 17473192; 17479438; 17545148; 17562024; 17567965; 17573555; 17578349; 17612563; 17617058; 17626784; 17634901; 17661145; 17673689; 17762162; 17851837; 17852426; 17897319; 17898861; 17912028; 17940864; 17943082; 17950068; 17962208; 17968796; 17986122; 17991726; 17991733; 18006148; 18036246; 18080773; 18088275; 18094008; 18096367; 18156174; 18167406; 18187620; 18212060; 18271526; 18271972; 18276761; 18292095; 18325497; 18349392; 18365874; 18382118; 18398039; 18434322; 18441095; 18463167; 18467441; 18483390; 18485152; 18487214; 18490463; 18511414; 18519765; 18543351; 18571008; 18583979; 18632979; 18676680; 18722874; 18757521; 18773861; 18813355; 18831963; 18844210; 18990689; 19010984; 19011936; 19014905; 19020743; 19032382; 19056867; 19064572; 19073827; 19074885; 19081071; 19086053; 19087984; 19110611; 19124506; 19127217; 19141999; 19144868; 19167371; 19170196; 19172394; 19179548; 19203995; 19236842; 19319135; 19336395; 19380191; 19388850; 19403524; 19415484; 19453261; 19460345; 19470771; 19484147; 19488063; 19491269; 19492417; 19520791; 19531499; 19544388; 19549686; 19549816; 19592671; 19604397; 19608641; 19619867; 19624835; 19625176; 19634110; 19670348; 19692168; 19708171; 19727227; 19749156; 19817957; 19823871; 19834535; 19840254; 19840943; 19853299; 19880507; 19887603; 19895983; 19896111; 19900104; 19913121; 19920151; 19921131; 19951549; 19953086; 19996314; 20033794; 20036812; 20092031; 20101173; 20108217; 20126978; 20127414; 20157331; 20158379; 20164030; 20169434; 20197289; 20201065; 20201926; 20203692; 20207214; 20303009; 20332099; 20351270; 20362419; 20364107; 20375273; 20379614; 20398806; 20412119; 20418097; 20423485; 20424473; 20429940; 20430735; 20444693; 20453000; 20466569; 20472833; 20482449; 20487573; 20498653; 20514023; 20564212; 20587610; 20598233; 20606012; 20621058; 20628086; 20628624; 20631636; 20634891; 20644561; 20674545; 20690902; 20714325; 20727496; 20727996; 20800603; 20818748; 20819124; 20830310; 20832399; 20851879; 20854793; 20889718; 20963824; 20969541; 21029725; 21048224; 21062739; 21087604; 21099256; 21123997; 21186997; 21187523; 21209099; 21212517; 21224998; 21236296; 21247755; 21273531; 21274378; 21309478; 21358296; 21376205; 21436680; 21439278; 21533003; 21567271; 21678081; 21752154; 21868386; 21872446; 21971700; 21982438; 22022452; 22033246; 22070650; 22087246; 22106858; 22122913; 22129558; 22236006; 22279551; 22293333; 22308022; 22401280; 22403631; 22404757; 22413835; 22416276; 22433566; 22457050; 22479527; 22479638; 22481252; 22493503; 22503865; 22504456; 22505024; 22532606; 22534548; 22574813; 22578596; 22621366; 22668508; 22677173; 22701712; 22721997; 22727668; 22745586; 22773267; 22782629; 22797360; 22829589; 22829952; 22852842; 22914212; 22925500; 22951723; 22990108; 23007402; 23090954; 23188118; 23201894; 23219876; 23229345; 23382691; 23403233; 23419149; 23457387; 23466131; 23542467; 23577098; 23608378; 23631828; 23645212; 23689072; 23711349; 23731208; 23790025; 23843455; 23869217; 23869762; 23899513; 23902938; 23936413; 23963773; 24036907; 24043306; 24045955 epidermal growth factor Ensembl:ENSG00000138798 HGNC:3229 HPRD:00578 MIM:131530 Vega:OTTHUMG00000132044 EGF Bin Zhao, Yue Liu, Oliver He ERBB ERBB1 HER1 PIG61 mENA WEB: http://www.ncbi.nlm.nih.gov/gene EGFR epidermal growth factor receptor 1956 7p12 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0000139 (EC: IEA); GO_0000165 (EC: NAS, PMID: 15542601); GO_0001503 (EC: NAS, PMID: 12925580); GO_0001889 (EC: IEA); GO_0001892 (EC: IEA); GO_0001934 (EC: IDA); GO_0001942 (EC: IEA); GO_0001948 (EC: IEA); GO_0003682 (EC: IDA); GO_0003690 (EC: NAS, PMID: 6325948); GO_0004709 (EC: NAS, PMID: 15542601); GO_0004713 (EC: IDA, PMID: 17115032); GO_0004713 (EC: IMP, PMID: 14702346); GO_0004713 (EC: TAS, PMID: 16076471); GO_0004714 (EC: TAS); GO_0004716 (EC: IEA); GO_0004888 (EC: IDA, PMID: 7736574); GO_0005006 (EC: IDA, PMID: 12435727); GO_0005006 (EC: NAS, PMID: 2790960); GO_0005178 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10026169); GO_0005524 (EC: IEA); GO_0005615 (EC: NAS, PMID: 9103388); GO_0005634 (EC: IDA, PMID: 12828935); GO_0005737 (EC: IDA); GO_0005768 (EC: IDA, PMID: 14702346); GO_0005789 (EC: IEA); GO_0005886 (EC: IDA); GO_0005886 (EC: TAS); GO_0005976 (EC: IEA); GO_0006412 (EC: IEA); GO_0006950 (EC: NAS, PMID: 12828935); GO_0006970 (EC: IEA); GO_0006979 (EC: IEA); GO_0007165 (EC: IDA, PMID: 10572067); GO_0007165 (EC: TAS); GO_0007166 (EC: IDA, PMID: 7736574); GO_0007173 (EC: IDA, PMID: 12435727); GO_0007173 (EC: TAS); GO_0007202 (EC: TAS, PMID: 12435727); GO_0007411 (EC: TAS); GO_0007435 (EC: IEA); GO_0007611 (EC: ISS); GO_0007623 (EC: IEA); GO_0008283 (EC: IDA, PMID: 17115032); GO_0008284 (EC: IDA, PMID: 7736574); GO_0008543 (EC: TAS); GO_0009986 (EC: IEA); GO_0010008 (EC: IEA); GO_0010960 (EC: IEA); GO_0016020 (EC: IDA, PMID: 12435727); GO_0016021 (EC: IEA); GO_0016101 (EC: IEA); GO_0016323 (EC: IDA, PMID: 12646923); GO_0016324 (EC: IEA); GO_0016337 (EC: IMP, PMID: 12435727); GO_0018108 (EC: IDA, PMID: 17115032); GO_0018108 (EC: IMP, PMID: 14702346); GO_0018108 (EC: TAS, PMID: 16076471); GO_0019694 (EC: IEA); GO_0019899 (EC: IPI, PMID: 12009895); GO_0019901 (EC: IEA); GO_0019903 (EC: IPI, PMID: 15899872); GO_0021795 (EC: IEA); GO_0030122 (EC: TAS, Qualifier: colocalizes_with, PMID: 14702346); GO_0030235 (EC: IDA, Qualifier: contributes_to, PMID: 12828935); GO_0030324 (EC: IEA); GO_0030335 (EC: IMP, PMID: 12435727); GO_0031659 (EC: IDA, PMID: 18483258); GO_0031965 (EC: IEA); GO_0032930 (EC: IEA); GO_0033590 (EC: IEA); GO_0033594 (EC: IEA); GO_0035413 (EC: IMP); GO_0035690 (EC: IEA); GO_0038095 (EC: TAS); GO_0042059 (EC: TAS); GO_0042177 (EC: IDA, PMID: 17115032); GO_0042327 (EC: IDA, PMID: 15082764); GO_0042698 (EC: IEA); GO_0042743 (EC: IEA); GO_0042802 (EC: IPI, PMID: 16777603); GO_0043006 (EC: TAS, PMID: 12435727); GO_0043066 (EC: IMP, PMID: 18070883); GO_0043235 (EC: IDA); GO_0043406 (EC: IDA, PMID: 10572067); GO_0043586 (EC: IEA); GO_0045087 (EC: TAS); GO_0045121 (EC: IDA, PMID: 12009895); GO_0045429 (EC: IDA, PMID: 12828935); GO_0045739 (EC: IDA, PMID: 17115032); GO_0045740 (EC: IDA, PMID: 17115032); GO_0045907 (EC: IEA); GO_0045909 (EC: IEA); GO_0045930 (EC: IEA); GO_0045944 (EC: IDA); GO_0046777 (EC: IMP, PMID: 18070883); GO_0046982 (EC: IDA, PMID: 10572067); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0048143 (EC: IEA); GO_0048146 (EC: IEA); GO_0048408 (EC: IEA); GO_0048471 (EC: IEA); GO_0048546 (EC: IEA); GO_0048661 (EC: IEA); GO_0050679 (EC: IDA, PMID: 10572067); GO_0050729 (EC: IEA); GO_0050730 (EC: IMP, PMID: 12435727); GO_0050999 (EC: IDA, PMID: 12828935); GO_0051015 (EC: IDA, PMID: 14702346); GO_0051205 (EC: TAS, PMID: 12435727); GO_0051592 (EC: IEA); GO_0051897 (EC: IMP, PMID: 17655843); GO_0051968 (EC: IEA); GO_0060571 (EC: IEA); GO_0070141 (EC: IDA, PMID: 18483258); GO_0070374 (EC: IDA); GO_0070435 (EC: ISS); GO_0071260 (EC: IEA); GO_0071364 (EC: ISS); GO_0071392 (EC: IDA); GO_0071549 (EC: IEA) PMID: 1281549; 1301150; 1309762; 1322798; 1333047; 1372092; 1382070; 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9447973; 9480911; 9488479; 9506989; 9506992; 9507002; 9528863; 9535896; 9544989; 9556602; 9617486; 9642287; 9658162; 9710451; 9733788; 9737977; 9756944; 9781061; 9815893; 9819414; 9837959; 9843575; 9872323; 9886492; 9890970; 9988678; 10026169; 10049786; 10075741; 10085134; 10086340; 10092522; 10187783; 10347170; 10358079; 10362357; 10369675; 10428778; 10435588; 10508618; 10523301; 10527633; 10558875; 10567358; 10571044; 10572067; 10595738; 10617627; 10618391; 10635327; 10648629; 10675333; 10722725; 10731668; 10734107; 10734310; 10777553; 10788520; 10799548; 10805725; 10806474; 10861448; 10888683; 10889023; 10913131; 10918300; 10918587; 10938113; 10953014; 10969083; 10971656; 10980697; 10985391; 10993906; 11094073; 11114724; 11116146; 11161793; 11172806; 11223155; 11226410; 11239464; 11278868; 11279102; 11286993; 11294897; 11349134; 11370743; 11375397; 11408594; 11432805; 11459228; 11467954; 11470832; 11483589; 11493652; 11500516; 11500850; 11504770; 11506178; 11516622; 11531336; 11533253; 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23404538; 23407558; 23408463; 23410174; 23411345; 23413122; 23416450; 23418353; 23418425; 23419507; 23423768; 23425899; 23429996; 23435217; 23441167; 23443279; 23449277; 23456637; 23457600; 23461856; 23464964; 23465277; 23468578; 23468851; 23470965; 23472148; 23472669; 23477725; 23485129; 23486266; 23486275; 23486338; 23491080; 23494210; 23495083; 23499740; 23513863; 23514946; 23517177; 23520442; 23520446; 23521519; 23525704; 23532252; 23536719; 23540867; 23546020; 23548265; 23548963; 23555046; 23555641; 23558893; 23559009; 23563092; 23564810; 23564819; 23565769; 23569038; 23575413; 23575414; 23581229; 23583406; 23589287; 23590575; 23594562; 23595626; 23599147; 23601297; 23602387; 23608326; 23614656; 23617883; 23620765; 23620784; 23625205; 23628526; 23633480; 23635774; 23636329; 23638794; 23643362; 23644172; 23650389; 23651790; 23653350; 23661635; 23665199; 23668355; 23675485; 23677180; 23685782; 23686431; 23690991; 23693078; 23698466; 23700486; 23704979; 23707073; 23707413; 23710458; 23720781; 23721103; 23722667; 23729361; 23729401; 23731208; 23736812; 23744486; 23744832; 23746767; 23749785; 23754287; 23754386; 23757022; 23758840; 23763474; 23764002; 23764753; 23765179; 23765574; 23771370; 23774213; 23774386; 23780873; 23786162; 23786997; 23787814; 23790025; 23791006; 23791944; 23792604; 23799367; 23799848; 23806066; 23817698; 23822636; 23827764; 23841084; 23844533; 23850692; 23861540; 23866081; 23867504; 23871709; 23880166; 23886169; 23888049; 23892415; 23897813; 23897956; 23903906; 23908594; 23909080; 23909081; 23916913; 23921085; 23927961; 23932319; 23932718; 23938604; 23940030; 23945382; 23945384; 23945389; 23945392; 23948418; 23956138; 23966299; 23966300; 23972990; 23974272; 23986462; 23990774; 23991943; 23991992; 23994953; 23999497; 24002608; 24007863; 24012640; 24014028; 24015256; 24019463; 24034250; 24038070; 24043629; 24046058; 24053674; 24055032; 24058967; 24063894; 24067727; 24075601; 24076656; 24082147; 24091658; 24113009; 24120917; 24135280; 24142702; 24145651; 24170107; 24189400; 24200637; 24211838; 24216759; 24222141; 24222150; 24222153; 24240702; 24253040; 24278442; 24304721; 24369725; 24391216; 24404585; 24413169; 24439929; 24457318; 24510991 epidermal growth factor receptor Ensembl:ENSG00000146648 HGNC:3236 HPRD:00579 MIM:131550 Vega:OTTHUMG00000023661 EGFR Bin Zhao, Yue Liu, Oliver He 4E-BP1 4EBP1 BP-1 PHAS-I WEB: http://www.ncbi.nlm.nih.gov/gene EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1978 8p12 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0000082 (EC: IMP, PMID: 14673156); GO_0002931 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10772338); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0006412 (EC: TAS); GO_0006413 (EC: TAS); GO_0008190 (EC: IEA); GO_0008286 (EC: TAS); GO_0010467 (EC: TAS); GO_0030324 (EC: IEA); GO_0030371 (EC: IDA); GO_0031333 (EC: IEA); GO_0031929 (EC: IDA, PMID: 12150926); GO_0043234 (EC: IEA); GO_0044267 (EC: TAS); GO_0045471 (EC: IEA); GO_0045931 (EC: IMP, PMID: 14673156); GO_0045947 (EC: IDA) PMID: 7651417; 7935836; 8083223; 8521827; 8816458; 8957083; 8975712; 9092573; 9344920; 9405468; 9465032; 9628874; 9806882; 10022874; 10092805; 10198256; 10364159; 10405182; 10608806; 10698949; 10713094; 10753870; 10772338; 10779345; 10942774; 10971657; 11069026; 11114166; 11146653; 11280764; 11438723; 11553333; 11605658; 11691836; 11777913; 11847216; 11865047; 11909977; 12071973; 12080086; 12105188; 12150925; 12150926; 12151318; 12271141; 12477932; 12588975; 12604610; 12618431; 12665511; 12665801; 12747827; 12759354; 12820960; 12912989; 14507920; 14673156; 15066126; 15094042; 15153109; 15178440; 15459249; 15467718; 15489334; 15542544; 15767663; 15809305; 15854902; 15927069; 16098202; 16098514; 16109716; 16169070; 16189514; 16242075; 16271312; 16648488; 16652388; 16715128; 16798736; 16824195; 16837165; 16873412; 16899564; 16983702; 17081983; 17114181; 17200342; 17254965; 17316564; 17353931; 17386266; 17502379; 17601486; 17604271; 17653084; 17693255; 17699757; 17724476; 18029348; 18051367; 18280804; 18337562; 18337751; 18384376; 18439897; 18442140; 18660489; 18668138; 18701920; 18708753; 18722121; 18810319; 18922789; 18957614; 19036825; 19107520; 19211763; 19244480; 19271249; 19336517; 19360336; 19367274; 19428047; 19429661; 19533653; 19541645; 19574449; 19603014; 19648884; 19834456; 19850923; 20090955; 20133758; 20304964; 20372058; 20532202; 20609351; 20621385; 20671708; 21046149; 21067588; 21071439; 21366462; 21460630; 21576371; 21661078; 21750861; 21784851; 21841310; 21900206; 21913890; 21914810; 21922152; 21964297; 22110663; 22142830; 22178476; 22184107; 22216185; 22248270; 22457629; 22493283; 22578813; 22586265; 22641346; 22652449; 22690797; 22918237; 22977662; 23082216; 23100465; 23175522; 23340172; 23451476; 23547259; 23640516; 23707523; 23814053; 24030155; 24211447; 24255178 eukaryotic translation initiation factor 4E binding protein 1 Ensembl:ENSG00000187840 HGNC:3288 HPRD:03746 MIM:602223 Vega:OTTHUMG00000164012 EIF4EBP1 Bin Zhao, Yue Liu, Oliver He EPH EPHT EPHT1 WEB: http://www.ncbi.nlm.nih.gov/gene EPHA1 EPH receptor A1 2041 7q34 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0001525 (EC: IEA); GO_0001954 (EC: IDA, PMID: 19118217); GO_0004672 (EC: IDA, PMID: 12775584); GO_0005005 (EC: IDA, PMID: 19118217); GO_0005524 (EC: IEA); GO_0005887 (EC: IDA, PMID: 19118217); GO_0006469 (EC: IDA, PMID: 19118217); GO_0007166 (EC: IDA, PMID: 19118217); GO_0008284 (EC: IMP); GO_0018108 (EC: IDA, PMID: 12775584); GO_0019901 (EC: IPI, PMID: 19118217); GO_0030335 (EC: IMP); GO_0030336 (EC: IDA, PMID: 19118217); GO_0032314 (EC: IDA, PMID: 19118217); GO_0032862 (EC: IDA, PMID: 19118217); GO_0034446 (EC: IDA, PMID: 19118217); GO_0045766 (EC: IMP); GO_0046777 (EC: IDA, PMID: 19118217); GO_0051496 (EC: ISS) PMID: 2825356; 8755474; 9267020; 9530499; 9576626; 10207129; 10369740; 10502115; 10730216; 11128993; 11256076; 11519828; 12477932; 12775584; 12853948; 14968112; 15146197; 15761153; 15951569; 16344560; 16737551; 16862074; 16964243; 17980912; 18308734; 18566674; 18590698; 18593464; 18728013; 18802966; 18990944; 19011600; 19118217; 19277044; 19525919; 19913121; 19949912; 20043122; 20596523; 20628086; 21042754; 21460840; 21460841; 21503576; 21906983; 22261062; 22362770; 22688511; 22939624; 23030051; 23429488 EPH receptor A1 Ensembl:ENSG00000146904 HGNC:3385 HPRD:01554 MIM:179610 Vega:OTTHUMG00000155894 EPHA1 Bin Zhao, Yue Liu, Oliver He IRE1 IRE1P IRE1a hIRE1p WEB: http://www.ncbi.nlm.nih.gov/gene ERN1 endoplasmic reticulum to nucleus signaling 1 2081 17q24.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000287 (EC: IDA, PMID: 9637683); GO_0004521 (EC: IDA, PMID: 11779465); GO_0004521 (EC: TAS); GO_0004674 (EC: IDA, PMID: 9637683); GO_0004674 (EC: TAS); GO_0005515 (EC: IPI, PMID: 11278723); GO_0005524 (EC: IDA, PMID: 9637683); GO_0005637 (EC: IEA); GO_0005739 (EC: IEA); GO_0005789 (EC: TAS); GO_0006351 (EC: IEA); GO_0006355 (EC: IEA); GO_0006468 (EC: IDA, PMID: 9637683); GO_0006987 (EC: IDA, PMID: 9637683); GO_0006987 (EC: TAS); GO_0007050 (EC: ISS); GO_0019899 (EC: IPI); GO_0030176 (EC: IDA, PMID: 9637683); GO_0030968 (EC: TAS); GO_0042802 (EC: IPI, PMID: 12637535); GO_0044267 (EC: TAS); GO_0046777 (EC: IEA); GO_0070055 (EC: IDA, PMID: 11779465); GO_0070059 (EC: IEA); GO_0090502 (EC: IDA, PMID: 11779465); GO_0090502 (EC: TAS); GO_1900103 (EC: IMP, PMID: 16645094) PMID: 9637683; 10587643; 10650002; 10737800; 11175748; 11278723; 11779465; 11850408; 11897784; 12050113; 12446770; 12477932; 12637535; 12843613; 14702039; 15063770; 15234121; 16107700; 16344560; 16645094; 16680093; 17585877; 17638880; 17951406; 17991856; 18065414; 18242182; 18369366; 18840095; 19135427; 19913121; 20007910; 20013084; 20103773; 20379614; 20447464; 20625543; 20628086; 20702765; 20798350; 20819778; 20965234; 21118962; 21385877; 21482118; 21525936; 21680894; 21954231; 22194594; 22199355; 22219383; 22314839; 22315414; 22419015; 22446326; 22718352; 22787145; 22917505; 23001845; 23041190; 23042294; 23103912; 23110043; 23363253; 23575540; 23598528; 23602568; 23684307; 23748775; 23752693; 23942232; 23950715; 24330607 endoplasmic reticulum to nucleus signaling 1 Ensembl:ENSG00000178607 HGNC:3449 HPRD:04943 MIM:604033 Vega:OTTHUMG00000178879 ERN1 Bin Zhao, Yue Liu, Oliver He ER ESR ESRA ESTRR Era NR3A1 WEB: http://www.ncbi.nlm.nih.gov/gene ESR1 estrogen receptor 1 2099 RP1-130E4.1 6q25.1 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0001046 (EC: IDA, PMID: 15345745); GO_0001547 (EC: IEA); GO_0002064 (EC: IEA); GO_0003682 (EC: IEA); GO_0003700 (EC: NAS, PMID: 12552091); GO_0003707 (EC: TAS, PMID: 10749889); GO_0005496 (EC: ISS); GO_0005515 (EC: IPI, PMID: 10359819); GO_0005634 (EC: IDA, PMID: 15569929); GO_0005654 (EC: TAS); GO_0005794 (EC: IEA); GO_0005886 (EC: IDA, PMID: 15569929); GO_0006338 (EC: NAS, PMID: 12351687); GO_0006351 (EC: TAS, PMID: 2040605); GO_0006355 (EC: NAS, PMID: 3753802); GO_0006367 (EC: TAS); GO_0007165 (EC: TAS, PMID: 10749889); GO_0007200 (EC: ISS); GO_0007204 (EC: ISS); GO_0008013 (EC: IPI, PMID: 15304487); GO_0008134 (EC: IEA); GO_0008209 (EC: IEA); GO_0008270 (EC: IEA); GO_0008584 (EC: IEA); GO_0010467 (EC: TAS); GO_0010629 (EC: IDA); GO_0010863 (EC: ISS); GO_0016020 (EC: NAS, PMID: 11960618); GO_0016021 (EC: IEA); GO_0019899 (EC: IPI, PMID: 12039952); GO_0030235 (EC: NAS, PMID: 12389206); GO_0030284 (EC: NAS, PMID: 3753802); GO_0030518 (EC: ISS); GO_0030520 (EC: NAS, PMID: 3753802); GO_0032355 (EC: IDA, PMID: 15304487); GO_0034056 (EC: IDA, PMID: 15345745); GO_0038052 (EC: IGI, PMID: 18722177); GO_0042802 (EC: IPI, PMID: 11265755); GO_0042981 (EC: IEA); GO_0043124 (EC: IDA, PMID: 16043358); GO_0043433 (EC: IDA, PMID: 10816575); GO_0043627 (EC: IDA, PMID: 11581164); GO_0045429 (EC: IDA); GO_0045944 (EC: IDA, PMID: 15345745); GO_0048146 (EC: IEA); GO_0048386 (EC: IDA, PMID: 15831516); GO_0051000 (EC: IDA); GO_0051091 (EC: IDA, PMID: 10681512); GO_0060065 (EC: IEA); GO_0060068 (EC: IEA); GO_0060523 (EC: IEA); GO_0060527 (EC: IEA); GO_0060687 (EC: IEA); GO_0060745 (EC: IEA); GO_0060749 (EC: IEA); GO_0060750 (EC: IEA); GO_0071392 (EC: ISS) PMID: 1476547; 1567414; 1577818; 1603086; 1779972; 2015052; 2040605; 2247153; 2792078; 3145193; 3753802; 3754034; 7476978; 7539106; 7641693; 7651415; 7838153; 7916651; 7923369; 8090165; 8221895; 8240974; 8308015; 8406468; 8524784; 8541239; 8598193; 8600444; 8600466; 8616895; 8647321; 8887632; 8961262; 9039267; 9058380; 9099865; 9115274; 9121466; 9171229; 9171231; 9192892; 9192902; 9195227; 9222609; 9259327; 9328340; 9338790; 9346901; 9393949; 9395481; 9427757; 9430642; 9448000; 9473491; 9489701; 9528769; 9600906; 9619507; 9627117; 9628876; 9628887; 9632676; 9653119; 9702189; 9710597; 9717844; 9765300; 9773978; 9773983; 9774463; 9774640; 9817600; 9841876; 9849967; 9875847; 9891036; 9892017; 10022127; 10085091; 10207098; 10334989; 10359819; 10428798; 10446910; 10454579; 10480874; 10490106; 10567404; 10598586; 10598587; 10619354; 10620335; 10648597; 10681512; 10706293; 10706618; 10706629; 10707955; 10713182; 10731636; 10737800; 10748020; 10749889; 10760302; 10766163; 10770935; 10816575; 10829018; 10866662; 10872826; 10903152; 10908561; 10938099; 10949034; 10970861; 11003650; 11004670; 11013076; 11014206; 11018265; 11029009; 11032808; 11043578; 11050077; 11050174; 11053406; 11073968; 11092403; 11092404; 11113179; 11113208; 11117529; 11121195; 11127213; 11139535; 11139588; 11140838; 11146623; 11149476; 11165056; 11178989; 11231990; 11239543; 11244506; 11250900; 11265755; 11266503; 11279242; 11316004; 11353774; 11355046; 11358671; 11358960; 11369763; 11376110; 11383910; 11389589; 11397855; 11429412; 11432835; 11435445; 11436125; 11437591; 11458981; 11458983; 11477071; 11481323; 11493692; 11507039; 11525424; 11555647; 11563984; 11564035; 11564893; 11574675; 11581164; 11591700; 11595700; 11595744; 11682624; 11682626; 11689445; 11689696; 11696545; 11704680; 11710886; 11716992; 11720251; 11731608; 11765043; 11773069; 11773441; 11773443; 11773444; 11774719; 11779858; 11782371; 11792840; 11795466; 11798902; 11803451; 11818499; 11818702; 11823467; 11826769; 11836633; 11838047; 11839580; 11844790; 11846326; 11854298; 11857578; 11861507; 11867202; 11867270; 11867769; 11875103; 11886765; 11887032; 11887937; 11894143; 11903314; 11911945; 11914066; 11918216; 11919305; 11922631; 11923430; 11923465; 11925413; 11931763; 11937504; 11938861; 11953755; 11955468; 11959092; 11959119; 11960618; 11971969; 11971975; 11981030; 11984699; 11986316; 11992565; 11997270; 12006396; 12011094; 12014437; 12021179; 12021200; 12031042; 12034840; 12039952; 12040178; 12059984; 12088102; 12088871; 12088878; 12093745; 12093804; 12096841; 12098649; 12100115; 12110951; 12111450; 12112006; 12112198; 12113882; 12115520; 12118371; 12119130; 12119550; 12138116; 12138194; 12145209; 12145334; 12145336; 12147702; 12154211; 12160997; 12167865; 12169981; 12174171; 12174912; 12183765; 12185415; 12193552; 12195069; 12198596; 12200415; 12206920; 12207170; 12207901; 12231116; 12242035; 12270131; 12351687; 12351689; 12374744; 12381474; 12389206; 12398989; 12400015; 12403846; 12412813; 12429765; 12438984; 12446585; 12453411; 12457453; 12466266; 12466272; 12475718; 12475719; 12477541; 12477932; 12479814; 12482846; 12482985; 12496244; 12509901; 12511607; 12515753; 12524070; 12527756; 12535528; 12547192; 12547836; 12552091; 12552233; 12553013; 12554660; 12554766; 12554772; 12556917; 12566449; 12566932; 12568733; 12574216; 12574227; 12576474; 12576490; 12588759; 12594000; 12594813; 12597128; 12605096; 12612060; 12612073; 12612084; 12627470; 12630920; 12639951; 12642782; 12646062; 12650698; 12660241; 12667452; 12682286; 12691862; 12710997; 12711000; 12712467; 12714702; 12718576; 12727987; 12727990; 12733715; 12736255; 12738788; 12740031; 12750288; 12757654; 12770739; 12774124; 12775708; 12781038; 12810552; 12815477; 12817755; 12821935; 12824724; 12837697; 12839940; 12842887; 12847685; 12852830; 12853125; 12855746; 12856811; 12861133; 12873981; 12873984; 12874288; 12878603; 12879219; 12889606; 12891629; 12894229; 12895004; 12895309; 12897156; 12899921; 12914574; 12915669; 12917323; 12917342; 12917706; 12927786; 12943695; 12943696; 12954762; 12961063; 12962497; 12962933; 12969589; 12970748; 13678390; 14499686; 14503979; 14504194; 14505233; 14506618; 14506733; 14508827; 14519529; 14520218; 14521715; 14522892; 14528100; 14528452; 14559803; 14562991; 14563649; 14568562; 14574404; 14600184; 14617632; 14630091; 14634838; 14670179; 14674143; 14675539; 14680815; 14688157; 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24389498; 24449583; 24449868 estrogen receptor 1 Ensembl:ENSG00000091831 HGNC:3467 HPRD:00589 MIM:133430 Vega:OTTHUMG00000016103 ESR1 Bin Zhao, Yue Liu, Oliver He CADTK CAKB FADK2 FAK2 PKB PTK PYK2 RAFTK WEB: http://www.ncbi.nlm.nih.gov/gene PTK2B protein tyrosine kinase 2 beta 2185 8p21.1 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0000165 (EC: IEA); GO_0001556 (EC: IEA); GO_0001666 (EC: IEA); GO_0001954 (EC: IMP, PMID: 18765415); GO_0002040 (EC: ISS); GO_0002315 (EC: ISS); GO_0004713 (EC: TAS, PMID: 8939945); GO_0004715 (EC: IDA, PMID: 7544443); GO_0004871 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10521452); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0005886 (EC: IEA); GO_0005925 (EC: IDA, PMID: 18765415); GO_0005938 (EC: IEA); GO_0006461 (EC: TAS, PMID: 10867021); GO_0006468 (EC: TAS, PMID: 7529876); GO_0006915 (EC: TAS, PMID: 10880513); GO_0006950 (EC: TAS, PMID: 8939945); GO_0006970 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10867021); GO_0007166 (EC: IMP, PMID: 8849729); GO_0007172 (EC: IEA); GO_0007173 (EC: IEA); GO_0007204 (EC: IEA); GO_0007229 (EC: IMP, PMID: 15050747); GO_0008284 (EC: IMP, PMID: 18765415); GO_0008285 (EC: IMP, PMID: 15050747); GO_0008360 (EC: IMP, PMID: 19086031); GO_0009612 (EC: IEA); GO_0009725 (EC: IEA); GO_0009749 (EC: IEA); GO_0010226 (EC: IEA); GO_0010595 (EC: IDA); GO_0010656 (EC: IEA); GO_0010752 (EC: IEA); GO_0010758 (EC: ISS); GO_0010976 (EC: IMP, PMID: 17910947); GO_0014009 (EC: IEA); GO_0014069 (EC: IEA); GO_0018108 (EC: IDA, PMID: 7544443); GO_0030027 (EC: IDA, PMID: 18765415); GO_0030155 (EC: IMP, PMID: 19086031); GO_0030307 (EC: IEA); GO_0030335 (EC: IMP, PMID: 18765415); GO_0030424 (EC: IEA); GO_0030426 (EC: IEA); GO_0030502 (EC: ISS); GO_0030826 (EC: IEA); GO_0030838 (EC: IMP, PMID: 18765415); GO_0031175 (EC: IEA); GO_0032403 (EC: IEA); GO_0032863 (EC: IEA); GO_0032960 (EC: ISS); GO_0033209 (EC: IMP, PMID: 8670418); GO_0042220 (EC: IEA); GO_0042493 (EC: IEA); GO_0042542 (EC: IEA); GO_0042976 (EC: IMP, PMID: 8670418); GO_0043066 (EC: IMP, PMID: 19880522); GO_0043149 (EC: IEA); GO_0043267 (EC: IDA, PMID: 7544443); GO_0043423 (EC: IEA); GO_0043507 (EC: IEA); GO_0043534 (EC: IEA); GO_0043552 (EC: ISS); GO_0045121 (EC: IEA); GO_0045428 (EC: IEA); GO_0045453 (EC: ISS); GO_0045471 (EC: IEA); GO_0045638 (EC: IMP, PMID: 15050747); GO_0045727 (EC: IEA); GO_0045766 (EC: IEA); GO_0045860 (EC: IMP, PMID: 7544443); GO_0046330 (EC: IMP, PMID: 8670418); GO_0046777 (EC: TAS, PMID: 8849729); GO_0048010 (EC: IMP); GO_0048041 (EC: IEA); GO_0048471 (EC: IDA, PMID: 18765415); GO_0050731 (EC: IDA); GO_0050848 (EC: IEA); GO_0051000 (EC: IEA); GO_0051279 (EC: ISS); GO_0051591 (EC: IEA); GO_0051592 (EC: IEA); GO_0070098 (EC: ISS); GO_0070374 (EC: IMP, PMID: 7544443); GO_0071300 (EC: IMP, PMID: 17910947); GO_2000058 (EC: IDA, PMID: 19880522); GO_2000060 (EC: IEA); GO_2000114 (EC: ISS); GO_2000249 (EC: ISS); GO_2000379 (EC: IEA); GO_2000538 (EC: ISS) PMID: 1718748; 7499242; 7529876; 7544443; 7673154; 8497321; 8670418; 8792832; 8798684; 8838818; 8849729; 8889548; 8939945; 8995252; 9020138; 9091579; 9099734; 9104812; 9242628; 9344848; 9362541; 9402324; 9422762; 9442086; 9446638; 9512511; 9545257; 9560226; 9565592; 9621077; 9750131; 9858471; 10022914; 10022920; 10082674; 10194422; 10229084; 10322114; 10329689; 10354709; 10356363; 10518561; 10521452; 10702271; 10708762; 10713673; 10747947; 10769033; 10777553; 10797305; 10821841; 10867021; 10880513; 10961871; 10980697; 11007796; 11036077; 11149930; 11162638; 11238453; 11278472; 11311138; 11337490; 11352632; 11461120; 11478920; 11493697; 11668182; 11683411; 11739373; 11744621; 11751905; 11774117; 11818507; 11820787; 11850124; 11856738; 11916084; 11937718; 12011061; 12063569; 12077257; 12082274; 12096713; 12231407; 12244133; 12354773; 12458207; 12477932; 12486027; 12515814; 12522270; 12576483; 12578912; 12606503; 12626562; 12628756; 12629171; 12771146; 12771190; 12794117; 12844492; 12857973; 12893833; 12933673; 12943720; 12960231; 14585963; 14676843; 14684825; 14729602; 14961028; 14963038; 14969582; 15050747; 15070849; 15105428; 15128501; 15128873; 15213840; 15489334; 15494733; 15499613; 15539082; 15557335; 15585656; 15588985; 15695828; 15717329; 15778498; 15835820; 15881658; 15944312; 15967096; 16055703; 16202977; 16344560; 16421571; 16433632; 16514607; 16751776; 16760434; 16774943; 16783820; 16840719; 16945503; 16949788; 16998626; 17192257; 17205062; 17329398; 17512525; 17537919; 17551499; 17563746; 17581868; 17716864; 17785844; 17906699; 17910947; 17950644; 18029348; 18075463; 18086875; 18198130; 18365874; 18367725; 18390748; 18437915; 18453587; 18507841; 18571765; 18632858; 18667434; 18765415; 18794150; 18832579; 18954908; 19047047; 19086031; 19106639; 19207108; 19358827; 19380485; 19415692; 19458494; 19509258; 19561089; 19661918; 19700666; 19706888; 19718025; 19880522; 19913121; 19919693; 19930834; 20028775; 20056178; 20074345; 20180987; 20215112; 20308428; 20379614; 20381867; 20543098; 20628086; 20688918; 20724588; 20800603; 20842205; 20849950; 20881009; 20946164; 20966971; 21114537; 21357692; 21424732; 21426305; 21533080; 21602932; 21640103; 21666110; 21840393; 21890473; 22023045; 22096562; 22188814; 22190034; 22454420; 22581436; 22745829; 22842493; 22859931; 22922962; 22923218; 22939624; 23142219; 23216754; 23220172; 23259602; 23292187; 23300847; 23302305; 23587524; 23618355; 23922106; 24072693; 24108181; 24176282 protein tyrosine kinase 2 beta Ensembl:ENSG00000120899 HGNC:9612 HPRD:03131 MIM:601212 Vega:OTTHUMG00000102082 PTK2B Bin Zhao, Yue Liu, Oliver He DGPT ERG9 SQS SS WEB: http://www.ncbi.nlm.nih.gov/gene FDFT1 farnesyl-diphosphate farnesyltransferase 1 2222 8p23.1-p22 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0004310 (EC: TAS); GO_0005783 (EC: IDA); GO_0005789 (EC: TAS); GO_0006694 (EC: TAS, PMID: 8474436); GO_0006695 (EC: TAS); GO_0008299 (EC: IEA); GO_0016021 (EC: IEA); GO_0016491 (EC: IEA); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0045338 (EC: IEA); GO_0051996 (EC: IEA) PMID: 7665618; 7685352; 7864626; 8020937; 8294001; 8474436; 10896663; 12477932; 14702039; 15489334; 16169070; 16684881; 17353931; 17483544; 17805225; 18029348; 18350552; 18636124; 18660489; 18676367; 19054015; 19245693; 19470168; 19738201; 19913121; 20031551; 20180986; 20403997; 20554694; 20628086; 20708005; 21139048; 21439984; 21890473; 21906983; 21945151; 21963094; 21987572; 22053931; 22268729; 22505724; 22546838; 22797925; 23000965; 23246001; 23455922; 23557589; 23752268; 23864651; 23956138; 24333579 farnesyl-diphosphate farnesyltransferase 1 Ensembl:ENSG00000079459 HGNC:3629 HPRD:01694 MIM:184420 Vega:OTTHUMG00000090801 FDFT1 Bin Zhao, Yue Liu, Oliver He FPPS FPS WEB: http://www.ncbi.nlm.nih.gov/gene FDPS farnesyl diphosphate synthase 2224 1q22 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0004161 (EC: IEA); GO_0004337 (EC: IEA); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005739 (EC: IEA); GO_0005829 (EC: TAS); GO_0006695 (EC: TAS); GO_0016032 (EC: IEA); GO_0033384 (EC: IEA); GO_0044281 (EC: TAS); GO_0044822 (EC: IDA); GO_0045337 (EC: IEA); GO_0046872 (EC: IEA) PMID: 1968462; 2018485; 2690933; 7584026; 8188698; 9030588; 10620343; 11160603; 11773414; 11785983; 12020352; 12107413; 12477932; 14702039; 15146197; 15342556; 15713990; 16344560; 16650801; 16684881; 16713569; 17198737; 17368768; 17387528; 17963374; 18029348; 18325729; 18327899; 18494934; 18660489; 18687167; 18781797; 19056481; 19060904; 19471022; 19494338; 20191015; 20450493; 20877624; 21139048; 21151198; 21196316; 21890473; 21906983; 21963094; 21987572; 22053931; 22278941; 22338925; 22407328; 22505724; 22863883; 23000965; 23234314; 23277274; 23847096; 23956138; 23998921; 24250222 farnesyl diphosphate synthase Ensembl:ENSG00000160752 HGNC:3631 HPRD:00606 MIM:134629 Vega:OTTHUMG00000013909 FDPS Bin Zhao, Yue Liu, Oliver He FKH1 FKHR FOXO1A WEB: http://www.ncbi.nlm.nih.gov/gene FOXO1 forkhead box O1 2308 13q14.1 20140408 9606 13 protein-coding Official from a nomenclature committee GO_0001078 (EC: IEA); GO_0001568 (EC: IBA); GO_0001659 (EC: ISS); GO_0001678 (EC: ISS); GO_0003682 (EC: ISS); GO_0005515 (EC: IPI, PMID: 11237865); GO_0005634 (EC: IDA, PMID: 11311120); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA, PMID: 11237865); GO_0005739 (EC: ISS); GO_0005829 (EC: ISS); GO_0005829 (EC: TAS); GO_0006473 (EC: ISS); GO_0006915 (EC: IEA); GO_0006974 (EC: ISS); GO_0007173 (EC: TAS); GO_0007389 (EC: IBA); GO_0008286 (EC: ISS); GO_0008301 (EC: IBA); GO_0008543 (EC: TAS); GO_0009267 (EC: ISS); GO_0009790 (EC: IBA); GO_0009888 (EC: IBA); GO_0031018 (EC: TAS); GO_0032873 (EC: IDA, PMID: 19696738); GO_0034599 (EC: ISS); GO_0035947 (EC: IEA); GO_0038095 (EC: TAS); GO_0042127 (EC: IEA); GO_0043066 (EC: IDA, PMID: 10871843); GO_0043565 (EC: IDA, PMID: 12228231); GO_0045087 (EC: TAS); GO_0045444 (EC: ISS); GO_0045599 (EC: ISS); GO_0045722 (EC: IEA); GO_0045892 (EC: ISS); GO_0045893 (EC: IDA, PMID: 10871843); GO_0045944 (EC: IDA, PMID: 10871843); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0051721 (EC: ISS); GO_0070417 (EC: ISS); GO_0071732 (EC: ISS); GO_2000505 (EC: ISS) PMID: 7630639; 7862145; 8275086; 8634710; 8790412; 9479491; 10358014; 10358075; 10783894; 10871843; 10973497; 11030146; 11237865; 11311120; 11353774; 11435445; 11672436; 11735247; 11893744; 11980723; 12039929; 12150827; 12163409; 12228231; 12242297; 12477932; 12482965; 12493691; 12519792; 12560069; 12606503; 12921955; 12960271; 12966085; 13679577; 14664696; 14726521; 15047604; 15057823; 15084259; 15109499; 15140004; 15184910; 15220471; 15342912; 15489334; 15582274; 15613482; 15632117; 15668399; 15688035; 15688409; 15692560; 15778376; 15890677; 15905404; 15987820; 16076959; 16100571; 16123151; 16133873; 16154098; 16282329; 16485043; 16492665; 16497530; 16571842; 16670089; 16690806; 16709600; 16849544; 16885156; 16916907; 16943287; 16950602; 16952014; 16952980; 16964289; 16973122; 16979636; 17030088; 17038621; 17050673; 17077083; 17202144; 17210752; 17218607; 17258205; 17285543; 17404186; 17442120; 17478621; 17490646; 17491598; 17525748; 17555999; 17556536; 17597184; 17599040; 17609436; 17613043; 17638879; 17873969; 17986608; 17993506; 18006475; 18022385; 18029348; 18096667; 18280254; 18301748; 18303411; 18316359; 18356527; 18408765; 18420577; 18483260; 18497882; 18497885; 18612045; 18660489; 18692812; 18713968; 18718910; 18786403; 18787186; 18788887; 18805788; 18815134; 18844239; 18951090; 18988640; 19049975; 19058789; 19075016; 19086408; 19103600; 19141580; 19150739; 19221179; 19233123; 19244250; 19254690; 19281796; 19293131; 19308286; 19321440; 19442434; 19463968; 19483080; 19503105; 19513505; 19535741; 19549905; 19563779; 19574223; 19584310; 19633686; 19675556; 19686743; 19696738; 19727442; 19740748; 19757185; 19772960; 19787258; 19793722; 19887561; 19893043; 19948975; 19953635; 19956688; 20018872; 20033803; 20061393; 20095040; 20125105; 20151947; 20351326; 20353756; 20357092; 20406953; 20412774; 20485516; 20543840; 20682687; 20719862; 20819778; 20868688; 20874444; 20884733; 20933505; 21069157; 21075101; 21116854; 21177767; 21177856; 21179458; 21185807; 21238503; 21298325; 21320536; 21321994; 21373837; 21388494; 21396404; 21423212; 21440011; 21440577; 21442235; 21505104; 21510935; 21539865; 21541992; 21613825; 21655267; 21666686; 21670150; 21696576; 21697492; 21708191; 21747041; 21775495; 21804543; 21993163; 22013015; 22072736; 22089931; 22159921; 22180177; 22197543; 22213032; 22266855; 22315317; 22343918; 22374423; 22389493; 22400069; 22411791; 22417654; 22454413; 22489460; 22515357; 22538365; 22552808; 22569260; 22622204; 22653055; 22675169; 22761423; 22761592; 22821817; 22865884; 22931788; 22992773; 23002242; 23025577; 23029264; 23035900; 23041154; 23059127; 23077062; 23105097; 23142810; 23160481; 23255113; 23263330; 23277279; 23291589; 23381604; 23389878; 23401241; 23460611; 23469153; 23532851; 23574718; 23603247; 23614736; 23615915; 23640897; 23686362; 23721824; 23733015; 23733882; 23748164; 23778262; 23799156; 23803610; 23814486; 23855308; 23865345; 23874926; 23995837; 24145170; 24268349; 24334454; 24374340 forkhead box O1 Ensembl:ENSG00000150907 HGNC:3819 HPRD:00645 MIM:136533 Vega:OTTHUMG00000016775 FOXO1 Bin Zhao, Yue Liu, Oliver He FMRP FRAXA POF POF1 WEB: http://www.ncbi.nlm.nih.gov/gene FMR1 fragile X mental retardation 1 2332 Xq27.3 20140408 9606 X protein-coding Official from a nomenclature committee GO_0003723 (EC: TAS, PMID: 8156595); GO_0003729 (EC: TAS, PMID: 7692601); GO_0005515 (EC: IPI, PMID: 10556305); GO_0005654 (EC: TAS, PMID: 10888599); GO_0005730 (EC: TAS, PMID: 16407062); GO_0005737 (EC: IDA); GO_0005737 (EC: TAS, PMID: 16407062); GO_0005845 (EC: ISS); GO_0007417 (EC: IEA); GO_0010494 (EC: IEA); GO_0042788 (EC: TAS, Qualifier: colocalizes_with, PMID: 12837692); GO_0043197 (EC: IEA); GO_0043198 (EC: IEA); GO_0044822 (EC: IDA); GO_0045202 (EC: IEA); GO_0045947 (EC: ISS); GO_0051028 (EC: IEA); GO_0071598 (EC: IEA) PMID: 1572655; 1710175; 1757956; 1913811; 2988332; 7141005; 7489725; 7633450; 7670500; 7688265; 7692601; 7781595; 7825604; 8069329; 8095365; 8156595; 8348153; 8358432; 8401496; 8401531; 8401578; 8490650; 8504300; 8515814; 8528261; 8668200; 8789445; 9302998; 9375856; 9497258; 9659908; 9829913; 10398250; 10527928; 10556305; 10567518; 10729312; 10888599; 11119302; 11129329; 11142760; 11142761; 11162447; 11256870; 11367701; 11415517; 11438699; 11443541; 11445641; 11545690; 11840495; 11854169; 11897823; 11992259; 12107447; 12112763; 12116230; 12116303; 12147688; 12210320; 12232854; 12378270; 12388589; 12417734; 12477932; 12515381; 12529854; 12594214; 12596051; 12745094; 12810982; 12837692; 12927206; 12950170; 14570712; 14599277; 14746957; 14747503; 14755444; 14993603; 15000256; 15065016; 15096575; 15121898; 15146197; 15175277; 15282548; 15300658; 15303970; 15377638; 15381024; 15381419; 15483045; 15483640; 15563507; 15608041; 15617547; 15629215; 15642922; 15659577; 15696166; 15741991; 15742217; 15805463; 15861180; 15879417; 15929093; 15930016; 15950084; 15956167; 15971024; 16006558; 16049924; 16055059; 16078053; 16117724; 16161415; 16184602; 16271017; 16319129; 16337617; 16361284; 16407062; 16456258; 16500716; 16500891; 16508954; 16636078; 16708166; 16793928; 16819831; 16891414; 16905681; 16907702; 17044853; 17097142; 17101793; 17179750; 17196195; 17283214; 17290448; 17506288; 17548778; 17588953; 17620491; 17674408; 17714511; 17850748; 17881655; 17917121; 17922850; 17932962; 17962727; 17966892; 17978095; 18057083; 18057320; 18074381; 18093976; 18163424; 18165971; 18172867; 18181681; 18211155; 18225979; 18273822; 18310361; 18310677; 18323308; 18357616; 18373410; 18384775; 18384784; 18403614; 18412117; 18413472; 18427356; 18471319; 18472033; 18487560; 18535897; 18553360; 18565783; 18570292; 18583885; 18628788; 18630123; 18632687; 18656952; 18664458; 18687789; 18789568; 18922172; 18973899; 19005212; 19026394; 19041959; 19056494; 19097999; 19105204; 19116286; 19147914; 19155329; 19193898; 19197218; 19204162; 19211207; 19215057; 19235102; 19249802; 19265746; 19273535; 19341325; 19361583; 19367323; 19396385; 19422761; 19436069; 19481741; 19487368; 19525339; 19542082; 19574928; 19574929; 19619908; 19642041; 19712568; 19728537; 19760650; 19764037; 19778484; 19794313; 19796183; 19804849; 19805454; 19806593; 19810826; 19853235; 19863547; 19864489; 19908235; 19927162; 20047076; 20059484; 20082462; 20118148; 20141036; 20149747; 20168238; 20187721; 20221430; 20228389; 20298211; 20301558; 20362512; 20378415; 20398889; 20410144; 20431035; 20435064; 20442204; 20473314; 20537351; 20562859; 20573435; 20597902; 20616364; 20629912; 20727716; 20734064; 20816038; 20843831; 20938029; 20955631; 20961665; 20981777; 21047554; 21116185; 21139048; 21179569; 21182205; 21209411; 21254619; 21254876; 21270637; 21276648; 21295394; 21335413; 21389081; 21427756; 21443343; 21445959; 21478165; 21484870; 21526209; 21554789; 21567456; 21576079; 21596781; 21597380; 21630353; 21639881; 21642970; 21651511; 21723415; 21749915; 21767618; 21775729; 21785977; 21786216; 21818263; 21868366; 21903422; 21909353; 21932336; 21944929; 21969264; 22001913; 22022567; 22080836; 22101959; 22102001; 22118674; 22157911; 22161987; 22207187; 22210492; 22211843; 22235103; 22251309; 22266345; 22351071; 22357842; 22387066; 22430918; 22438971; 22489017; 22493044; 22498846; 22507827; 22528549; 22539853; 22561129; 22568721; 22573456; 22579290; 22581803; 22584570; 22586326; 22619118; 22708486; 22737234; 22797890; 22797925; 22808956; 22811313; 22842191; 22863780; 22880518; 22887750; 22890812; 22903700; 22914733; 22924671; 22963248; 22984553; 22993428; 23009394; 23060046; 23084401; 23111161; 23123760; 23154068; 23211703; 23219959; 23235829; 23298734; 23307923; 23313071; 23356558; 23390134; 23392687; 23504400; 23523717; 23528734; 23537988; 23560306; 23660422; 23731704; 23740716; 23753897; 23760159; 23824909; 23867198; 23874213; 23896050; 24141422; 24207117; 24249225; 24250222; 24289922; 24457600 fragile X mental retardation 1 Ensembl:ENSG00000102081 HGNC:3775 HPRD:02398 MIM:309550 Vega:OTTHUMG00000022606 FMR1 Bin Zhao, Yue Liu, Oliver He FPTA PGGT1A PTAR2 WEB: http://www.ncbi.nlm.nih.gov/gene FNTA farnesyltransferase, CAAX box, alpha 2339 8p11 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0004660 (EC: IDA, PMID: 16893176); GO_0004660 (EC: IDA, Qualifier: contributes_to, PMID: 19228685); GO_0004661 (EC: IDA, PMID: 16893176); GO_0004662 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11687658); GO_0005737 (EC: TAS, PMID: 8599089); GO_0005829 (EC: TAS); GO_0005875 (EC: IDA, PMID: 19228685); GO_0005953 (EC: IDA, PMID: 16893176); GO_0005965 (EC: IDA, PMID: 16893176); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0007179 (EC: TAS, PMID: 8599089); GO_0007603 (EC: TAS); GO_0008017 (EC: IDA, PMID: 19228685); GO_0016056 (EC: TAS); GO_0018343 (EC: IDA, PMID: 16893176); GO_0018344 (EC: IDA, PMID: 16893176); GO_0022400 (EC: TAS); GO_0043014 (EC: IDA, PMID: 19228685); GO_0090044 (EC: IDA, PMID: 19228685); GO_0090045 (EC: IDA, PMID: 19228685) PMID: 1400319; 2217184; 7713879; 8106351; 8175923; 8276393; 8419339; 8494894; 8530343; 8599089; 8830800; 8889548; 8910345; 10676968; 10747914; 10852915; 11313965; 11598000; 11687658; 12036349; 12374986; 12477932; 12825937; 14702039; 15170324; 15451670; 15489334; 16893176; 17192483; 17353931; 18187620; 18406652; 18654987; 19228685; 19841875; 20403997; 21139048; 21906983; 21988832; 22160308; 22863883; 23602568 farnesyltransferase, CAAX box, alpha Ensembl:ENSG00000168522 HGNC:3782 HPRD:00607 MIM:134635 Vega:OTTHUMG00000165279 FNTA Bin Zhao, Yue Liu, Oliver He FRAP FRAP1 FRAP2 RAFT1 RAPT1 WEB: http://www.ncbi.nlm.nih.gov/gene MTOR mechanistic target of rapamycin (serine/threonine kinase) 2475 1p36.2 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000139 (EC: IEA); GO_0001030 (EC: IDA); GO_0001031 (EC: IDA); GO_0001032 (EC: IDA); GO_0001156 (EC: IDA); GO_0001934 (EC: IDA); GO_0001938 (EC: IEA); GO_0004674 (EC: IDA, PMID: 15467718); GO_0004674 (EC: TAS); GO_0005515 (EC: IPI, PMID: 10089303); GO_0005524 (EC: IEA); GO_0005737 (EC: IDA, PMID: 11853878); GO_0005741 (EC: IEA); GO_0005764 (EC: IDA); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005789 (EC: IEA); GO_0005829 (EC: TAS); GO_0005942 (EC: NAS, PMID: 15539461); GO_0005979 (EC: IEA); GO_0006468 (EC: IDA, PMID: 15467718); GO_0006468 (EC: IMP, PMID: 17028174); GO_0006950 (EC: IMP, PMID: 17028174); GO_0007165 (EC: NAS, PMID: 15539461); GO_0007173 (EC: TAS); GO_0007281 (EC: IEA); GO_0007584 (EC: NAS, PMID: 15539461); GO_0008144 (EC: IEA); GO_0008286 (EC: TAS); GO_0008543 (EC: TAS); GO_0010507 (EC: ISS); GO_0010592 (EC: IEA); GO_0010628 (EC: IMP, PMID: 17028174); GO_0010831 (EC: IEA); GO_0012505 (EC: IDA, PMID: 18497260); GO_0016020 (EC: IDA, PMID: 11853878); GO_0016049 (EC: IDA, PMID: 18762023); GO_0016049 (EC: TAS, PMID: 11853878); GO_0016242 (EC: IEA); GO_0016301 (EC: IDA, PMID: 15467718); GO_0016301 (EC: TAS, PMID: 11853878); GO_0016310 (EC: IDA, PMID: 11853878); GO_0016605 (EC: ISS, Qualifier: colocalizes_with); GO_0018105 (EC: IMP); GO_0018107 (EC: IEA); GO_0019904 (EC: IEA); GO_0030163 (EC: TAS, PMID: 11853878); GO_0030838 (EC: IEA); GO_0031295 (EC: TAS); GO_0031529 (EC: IEA); GO_0031669 (EC: ISS); GO_0031929 (EC: IMP, PMID: 15467718); GO_0031931 (EC: IDA, PMID: 15467718); GO_0031931 (EC: IMP); GO_0031932 (EC: IDA, PMID: 15467718); GO_0031998 (EC: IEA); GO_0032095 (EC: IEA); GO_0032314 (EC: IEA); GO_0032956 (EC: IMP, PMID: 15467718); GO_0038095 (EC: TAS); GO_0040007 (EC: NAS, PMID: 15539461); GO_0043022 (EC: IEA); GO_0043200 (EC: IDA, PMID: 18497260); GO_0043610 (EC: IEA); GO_0045087 (EC: TAS); GO_0045727 (EC: IDA, PMID: 18762023); GO_0045792 (EC: IEA); GO_0045859 (EC: IEA); GO_0045945 (EC: IMP); GO_0046777 (EC: IDA, PMID: 15467718); GO_0046889 (EC: IMP, PMID: 18762023); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0050731 (EC: IEA); GO_0051219 (EC: IPI, PMID: 11853878); GO_0051496 (EC: IEA); GO_0051534 (EC: IEA); GO_0051897 (EC: IEA); GO_0070438 (EC: IEA); GO_0071456 (EC: ISS) PMID: 7539137; 7809080; 7822316; 8008069; 8083223; 8660990; 8662507; 9092573; 9099849; 9405468; 9434772; 9465032; 9653645; 10089303; 10200280; 10325225; 10364159; 10567431; 10660304; 10664457; 10698949; 10702316; 10753870; 10779345; 10910062; 10942774; 10971657; 11114166; 11279232; 11287630; 11426320; 11438723; 11602639; 11691836; 11691993; 11729323; 11733037; 11777913; 11853878; 11884412; 11914378; 11930000; 11967149; 12000755; 12030785; 12080086; 12105188; 12145207; 12150925; 12150926; 12172553; 12231510; 12242281; 12271141; 12370290; 12408816; 12477932; 12558800; 12604610; 12665511; 12718876; 12719976; 12747827; 12796477; 12807916; 12813467; 12820960; 12912989; 14578359; 14668532; 14679009; 14729629; 14970221; 15001544; 15004009; 15028555; 15056668; 15066126; 15150271; 15161933; 15218033; 15268862; 15284440; 15292274; 15317677; 15342556; 15388791; 15452223; 15459249; 15467718; 15489334; 15489897; 15496972; 15522880; 15539461; 15576463; 15580312; 15584862; 15604215; 15605414; 15623621; 15624760; 15632115; 15632201; 15657358; 15659381; 15702344; 15708965; 15718470; 15723049; 15755954; 15767663; 15772076; 15796538; 15802268; 15809305; 15843522; 15854902; 15878852; 15896331; 15899889; 15905173; 15953364; 16006564; 16027121; 16049009; 16098202; 16098514; 16099944; 16109716; 16141350; 16183647; 16221682; 16242075; 16282343; 16286006; 16341243; 16354680; 16407298; 16427044; 16452250; 16467080; 16541103; 16543150; 16603397; 16631613; 16652388; 16710414; 16786123; 16798736; 16818690; 16824195; 16837165; 16847060; 16849522; 16870609; 16874098; 16884363; 16912159; 16912980; 16914728; 16915281; 16916907; 16919458; 16922504; 16927414; 16929481; 16954686; 16959214; 16962653; 16963469; 17016437; 17018601; 17028174; 17043309; 17052453; 17075574; 17102641; 17110454; 17114181; 17148679; 17215282; 17253963; 17277771; 17289850; 17318075; 17329400; 17329620; 17351147; 17360675; 17363738; 17372934; 17386266; 17409838; 17461779; 17463046; 17470430; 17482291; 17483438; 17488873; 17545512; 17553806; 17562705; 17562865; 17565979; 17595159; 17604271; 17616684; 17616691; 17631500; 17640392; 17656678; 17683115; 17693255; 17698027; 17721885; 17724079; 17726467; 17889116; 17897319; 17911267; 17914450; 17928295; 17935273; 17942603; 17990907; 17991864; 17993259; 17996122; 18006825; 18048359; 18056791; 18160036; 18215133; 18235224; 18247380; 18250445; 18276609; 18292222; 18337562; 18337751; 18339839; 18339899; 18348264; 18351386; 18372248; 18395956; 18413763; 18423201; 18426977; 18434090; 18483275; 18494264; 18497260; 18505677; 18511708; 18519641; 18548093; 18563337; 18566587; 18570873; 18596736; 18612547; 18622747; 18650380; 18652687; 18658153; 18660489; 18678646; 18697743; 18702307; 18704194; 18715846; 18722121; 18725988; 18757300; 18762023; 18769127; 18769147; 18776922; 18787170; 18794342; 18807177; 18813808; 18824293; 18826385; 18831768; 18842593; 18848473; 18924132; 18925875; 18926585; 18929564; 18945681; 18948269; 18953439; 18980674; 18990449; 19018001; 19019920; 19020722; 19020730; 19054297; 19074768; 19078992; 19090006; 19098000; 19107520; 19107873; 19108833; 19121088; 19145465; 19147678; 19147764; 19147772; 19147966; 19155728; 19164214; 19176054; 19176518; 19176689; 19201859; 19203585; 19203829; 19211835; 19222999; 19223493; 19223902; 19225151; 19225536; 19234517; 19240722; 19244117; 19258318; 19285014; 19293424; 19299575; 19301157; 19321861; 19331815; 19341427; 19357233; 19371356; 19373664; 19402821; 19414743; 19416884; 19446321; 19454477; 19487463; 19489223; 19505958; 19509151; 19535348; 19539012; 19553685; 19553815; 19553991; 19561084; 19564927; 19587219; 19608873; 19615795; 19619545; 19624311; 19648884; 19654299; 19657638; 19679016; 19680556; 19690328; 19698731; 19724909; 19725049; 19726679; 19739122; 19757306; 19771169; 19788500; 19789507; 19789631; 19794149; 19797172; 19815051; 19838215; 19864431; 19875696; 19875983; 19881535; 19889638; 19897009; 19914247; 19935716; 19935854; 19936974; 19949304; 19954658; 19955088; 19956179; 19956839; 19956876; 19956903; 19966861; 20005306; 20009539; 20019839; 20022946; 20030877; 20038818; 20048174; 20053679; 20061787; 20070283; 20080789; 20081105; 20093977; 20133820; 20137118; 20145209; 20150565; 20153512; 20157617; 20160076; 20166697; 20166753; 20169205; 20176935; 20182617; 20190810; 20196784; 20204306; 20207176; 20226010; 20227368; 20232298; 20232305; 20233713; 20236941; 20299603; 20308064; 20335217; 20338061; 20338997; 20339946; 20354165; 20354178; 20360610; 20368287; 20372862; 20375166; 20375271; 20379614; 20381137; 20386866; 20388784; 20395440; 20410302; 20412774; 20424163; 20424326; 20427287; 20427710; 20438709; 20439490; 20447721; 20453000; 20457610; 20459645; 20459775; 20460933; 20479250; 20480226; 20488790; 20491627; 20517583; 20537536; 20542007; 20542987; 20543138; 20562859; 20606252; 20607654; 20622004; 20628002; 20630061; 20656459; 20668229; 20673489; 20679884; 20717925; 20727662; 20727967; 20801936; 20805015; 20805416; 20809949; 20811722; 20811725; 20817788; 20828737; 20837708; 20855840; 20857497; 20861467; 20864032; 20874802; 20884115; 20929525; 20960030; 21033251; 21035469; 21035497; 21040950; 21045808; 21046231; 21048031; 21062981; 21062993; 21071439; 21071597; 21092676; 21095582; 21113813; 21123297; 21139048; 21145759; 21159731; 21170086; 21177249; 21177869; 21199794; 21203441; 21212465; 21223797; 21228927; 21239045; 21242970; 21246613; 21258367; 21264294; 21266827; 21276607; 21277936; 21283628; 21289308; 21290341; 21294052; 21304100; 21307192; 21317285; 21320304; 21321085; 21325052; 21326036; 21329734; 21334199; 21336308; 21360636; 21367918; 21368105; 21372221; 21373201; 21383697; 21412012; 21422248; 21428914; 21428925; 21430254; 21440577; 21444676; 21454807; 21458454; 21460630; 21460850; 21464729; 21471201; 21501360; 21510936; 21512002; 21513566; 21531565; 21532145; 21541441; 21548803; 21555591; 21559457; 21567173; 21576368; 21577328; 21606591; 21609291; 21631271; 21659604; 21665993; 21667012; 21673516; 21681021; 21696297; 21701776; 21702994; 21707707; 21707714; 21718677; 21725971; 21734039; 21738705; 21744334; 21757621; 21763898; 21763970; 21763972; 21768204; 21785113; 21793913; 21795849; 21802763; 21821699; 21822208; 21822266; 21832856; 21837670; 21859551; 21861134; 21874010; 21881486; 21886838; 21887223; 21890410; 21890473; 21898543; 21900206; 21906983; 21914810; 21926965; 21931802; 21933144; 21939655; 21941369; 21943204; 21949121; 21949767; 21949775; 21963299; 21963359; 21965657; 21971509; 21973240; 21980128; 21981924; 21987434; 21987572; 22007913; 22015781; 22017875; 22017876; 22017877; 22024086; 22024166; 22025552; 22029423; 22031597; 22045983; 22053105; 22094587; 22105511; 22127531; 22142830; 22148961; 22199311; 22214661; 22216185; 22223645; 22248270; 22248718; 22253885; 22258093; 22268788; 22285859; 22285861; 22287548; 22320958; 22328503; 22338078; 22339676; 22340595; 22343475; 22343943; 22349822; 22354785; 22356909; 22367541; 22369257; 22399302; 22399812; 22408252; 22409888; 22424946; 22441547; 22452883; 22455872; 22457328; 22457523; 22469187; 22471665; 22483750; 22493283; 22504639; 22505595; 22505724; 22509023; 22509811; 22544753; 22549934; 22556133; 22556409; 22562131; 22570149; 22576015; 22586326; 22595285; 22607554; 22612812; 22619175; 22619737; 22620485; 22627626; 22648906; 22674982; 22685542; 22696419; 22696681; 22729223; 22752785; 22753663; 22761730; 22768106; 22797077; 22813852; 22815832; 22826320; 22833529; 22840496; 22841170; 22863784; 22863883; 22863900; 22871496; 22886792; 22895079; 22895785; 22898570; 22899290; 22902049; 22907398; 22907434; 22920721; 22924455; 22944293; 22952422; 22955108; 22958932; 22960547; 22967500; 22977662; 22983984; 22987636; 22989749; 22990118; 23000302; 23022044; 23027127; 23027611; 23027865; 23035115; 23061800; 23064282; 23080369; 23084634; 23091295; 23095638; 23103253; 23107319; 23110147; 23115234; 23150676; 23160380; 23162107; 23165769; 23167739; 23169238; 23173671; 23178462; 23184942; 23209702; 23216249; 23246968; 23276696; 23277194; 23283505; 23284171; 23291726; 23296986; 23297343; 23297824; 23297825; 23318419; 23322780; 23325216; 23332779; 23337583; 23340270; 23348097; 23363784; 23375848; 23383273; 23395818; 23400783; 23412940; 23416721; 23423739; 23434734; 23440206; 23444213; 23444380; 23451476; 23454121; 23524405; 23524951; 23530221; 23536724; 23541542; 23544944; 23549875; 23555892; 23573198; 23585566; 23592839; 23601218; 23614736; 23623586; 23626817; 23632629; 23636326; 23660068; 23671028; 23684925; 23686362; 23686804; 23691056; 23693095; 23720219; 23722547; 23728790; 23762398; 23773481; 23797151; 23798432; 23828865; 23832540; 23841076; 23863161; 23867512; 23871289; 23872956; 23878245; 23878397; 23883112; 23886172; 23898069; 23911927; 23913957; 23933173; 23953228; 23956138; 23983265; 24011934; 24023300; 24027431; 24067973; 24078802; 24122995; 24164895; 24323026; 24334141; 24457600; 24481845 mechanistic target of rapamycin (serine/threonine kinase) Ensembl:ENSG00000198793 HGNC:3942 HPRD:03134 MIM:601231 Vega:OTTHUMG00000002001 MTOR Bin Zhao, Yue Liu, Oliver He LFTD NBIA3 WEB: http://www.ncbi.nlm.nih.gov/gene FTL ferritin, light polypeptide 2512 19q13.33 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005506 (EC: IDA, PMID: 19923220); GO_0005515 (EC: IPI, PMID: 16169070); GO_0005829 (EC: TAS); GO_0006826 (EC: IEA); GO_0006879 (EC: TAS); GO_0006892 (EC: TAS); GO_0008043 (EC: IDA, PMID: 19923220); GO_0008199 (EC: IEA); GO_0008219 (EC: IEA); GO_0042802 (EC: IPI, PMID: 16169070); GO_0055072 (EC: TAS, PMID: 19923220); GO_0055085 (EC: TAS); GO_0061024 (EC: TAS); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 659425; 2821803; 3000916; 3023856; 3291676; 3754330; 3840162; 3857215; 3858810; 6572903; 6653779; 7492760; 7493028; 7575610; 8041631; 8554925; 8630420; 8636399; 8706699; 8781450; 8864140; 9119260; 9169099; 9196065; 9226182; 9292547; 9414300; 9414313; 9457670; 9526618; 10491119; 10753629; 10759702; 10828006; 11031247; 11252894; 11438811; 11591653; 11783942; 11849230; 12071855; 12199804; 12200611; 12387819; 12401807; 12459518; 12477932; 12646258; 12746423; 14615048; 15099026; 15231747; 15231748; 15390032; 15489334; 15727900; 15835264; 16116125; 16169070; 16189514; 16217041; 16222695; 16252260; 16289162; 16790936; 16822677; 16858508; 17116749; 17459943; 17601350; 17660802; 17761032; 17970701; 18061976; 18160403; 18413574; 18486613; 18586377; 18621011; 18624398; 18665827; 18755684; 18977241; 19056867; 19176363; 19254706; 19318681; 19519778; 19781644; 19787796; 19910193; 19923220; 20088381; 20159981; 20301320; 20345975; 20381070; 20471030; 20689807; 21029774; 21103663; 21139048; 21139976; 21541272; 21555518; 21696736; 21800051; 21906983; 21907119; 22020773; 22117997; 22248276; 22348978; 22359459; 22535864; 22760008; 22863883; 22939629; 23029420; 23080069; 23119080; 23275563; 23300545; 23381919; 23421845; 23463506; 23592921; 23685131; 23699174 ferritin, light polypeptide Ensembl:ENSG00000087086 HGNC:3999 HPRD:00616 MIM:134790 Vega:OTTHUMG00000183332 FTL Bin Zhao, Yue Liu, Oliver He SLK SYN p59-FYN WEB: http://www.ncbi.nlm.nih.gov/gene FYN FYN oncogene related to SRC, FGR, YES 2534 RP1-66H14.1 6q21 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0001764 (EC: IEA); GO_0001948 (EC: IPI, PMID: 16831868); GO_0004713 (EC: EXP); GO_0004713 (EC: TAS); GO_0004715 (EC: NAS, PMID: 7822789); GO_0005515 (EC: IPI, PMID: 10209036); GO_0005524 (EC: IEA); GO_0005634 (EC: IEA); GO_0005739 (EC: IEA); GO_0005768 (EC: IDA, PMID: 15611048); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 12150984); GO_0006468 (EC: NAS, PMID: 7822789); GO_0006816 (EC: NAS, PMID: 7822789); GO_0007173 (EC: TAS); GO_0007411 (EC: TAS); GO_0007596 (EC: TAS); GO_0007612 (EC: TAS, PMID: 1361685); GO_0007631 (EC: TAS, PMID: 8264796); GO_0008360 (EC: IEA); GO_0008543 (EC: TAS); GO_0010629 (EC: IEA); GO_0010976 (EC: IEA); GO_0014069 (EC: IEA); GO_0015631 (EC: IEA); GO_0016032 (EC: TAS); GO_0030168 (EC: TAS); GO_0030900 (EC: IEA); GO_0031295 (EC: TAS); GO_0035556 (EC: TAS, PMID: 1361685); GO_0038095 (EC: TAS); GO_0038096 (EC: TAS); GO_0042177 (EC: IEA); GO_0042493 (EC: IEA); GO_0042608 (EC: IEA); GO_0042609 (EC: IEA); GO_0042610 (EC: IEA); GO_0043548 (EC: IEA); GO_0044325 (EC: IEA); GO_0045087 (EC: TAS); GO_0045121 (EC: IDA, Qualifier: colocalizes_with, PMID: 12150984); GO_0045471 (EC: IEA); GO_0046777 (EC: IEA); GO_0046872 (EC: IEA); GO_0046875 (EC: IPI, PMID: 10498895); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0048813 (EC: IEA); GO_0050690 (EC: TAS); GO_0050798 (EC: IEA); GO_0050852 (EC: IDA, PMID: 7722293); GO_0050900 (EC: TAS); GO_0050966 (EC: IEA); GO_0051428 (EC: IEA); GO_0070851 (EC: IPI, PMID: 16479011); GO_0071375 (EC: IEA); GO_1900182 (EC: IEA); GO_2001240 (EC: IEA) PMID: 82; 119942; 1334406; 1351058; 1361685; 1384720; 1385527; 1387715; 1446976; 1454062; 1530920; 1544885; 1696179; 1699196; 1715582; 1717997; 1985196; 3099169; 3330788; 3526330; 7504057; 7515933; 7516469; 7517401; 7521304; 7525550; 7537495; 7545683; 7565724; 7588629; 7589084; 7589101; 7589480; 7595520; 7642581; 7664083; 7681396; 7682059; 7687536; 7722293; 7760813; 7782294; 7822789; 7859737; 7929439; 8058772; 8104794; 8262983; 8264796; 8294442; 8394019; 8395016; 8483935; 8493579; 8566014; 8621384; 8621719; 8626376; 8626543; 8631859; 8655574; 8662998; 8671590; 8681387; 8756631; 8760790; 8798684; 8805332; 8805554; 8810341; 8883579; 8900205; 8910336; 8961927; 8980254; 8995358; 8995379; 9028946; 9032261; 9038134; 9043947; 9045636; 9047237; 9060467; 9079653; 9091579; 9104812; 9118959; 9121430; 9169421; 9185665; 9188452; 9195899; 9195918; 9196040; 9207119; 9230816; 9252391; 9269777; 9295288; 9311917; 9344703; 9344857; 9351806; 9351809; 9360983; 9366405; 9368621; 9417082; 9425276; 9446569; 9507006; 9531288; 9535845; 9535867; 9553134; 9573028; 9576921; 9603925; 9632142; 9648856; 9670010; 9674711; 9677430; 9687533; 9710204; 9712716; 9741627; 9748251; 9750131; 9756930; 9763511; 9778343; 9799234; 9804857; 9819391; 9822663; 9837776; 9837978; 9846481; 9856337; 9890970; 9892651; 9973379; 10022833; 10089404; 10092522; 10196263; 10209036; 10212213; 10224664; 10229084; 10339567; 10383400; 10435619; 10447714; 10458595; 10482988; 10498895; 10532312; 10544125; 10551884; 10564280; 10570256; 10571044; 10571082; 10586033; 10591186; 10629042; 10636929; 10642173; 10708762; 10733577; 10739664; 10744724; 10764799; 10790433; 10799548; 10804218; 10816433; 10829062; 10858437; 10867021; 10871840; 10872802; 10896916; 10921922; 10945997; 11005864; 11024032; 11075717; 11078745; 11087735; 11121167; 11149959; 11157475; 11158295; 11162638; 11204284; 11239464; 11262396; 11278378; 11278857; 11298344; 11353545; 11356869; 11423543; 11466305; 11483358; 11483655; 11526103; 11536198; 11546790; 11594778; 11598189; 11604131; 11677266; 11684709; 11711534; 11724572; 11739737; 11741599; 11741929; 11744621; 11777936; 11806999; 11820784; 11826099; 11839780; 11943772; 11943848; 11960376; 11983687; 11994282; 12084815; 12089510; 12096713; 12138090; 12150984; 12171928; 12181444; 12218089; 12231245; 12237775; 12244095; 12244174; 12368035; 12370810; 12372285; 12374739; 12408980; 12419528; 12426371; 12431372; 12450793; 12458214; 12471123; 12477932; 12496362; 12509223; 12524444; 12526739; 12529448; 12538589; 12545174; 12558988; 12589038; 12640114; 12660731; 12668668; 12670706; 12695509; 12697812; 12730241; 12753742; 12788081; 12835311; 12846735; 12857875; 12893833; 12917446; 12932824; 12941616; 14506255; 14517306; 14530346; 14574404; 14647465; 14662334; 14675807; 14684825; 14702039; 14757743; 14761954; 14761972; 14965316; 14980517; 14993658; 14999081; 15033366; 15078178; 15082191; 15098360; 15144186; 15169881; 15175272; 15190072; 15206927; 15208330; 15345594; 15345598; 15489334; 15494732; 15514010; 15536091; 15537652; 15556646; 15557120; 15588985; 15611048; 15638726; 15707590; 15708437; 15713745; 15872086; 15925565; 16014719; 16115884; 16145685; 16237174; 16316995; 16344560; 16374509; 16387660; 16400523; 16454711; 16479011; 16503409; 16537602; 16597701; 16713569; 16777849; 16782058; 16818765; 16831868; 16860569; 16882656; 16888650; 16891393; 16899217; 16938345; 16964398; 17129785; 17130124; 17164290; 17189269; 17192257; 17334644; 17417065; 17474147; 17599905; 17701175; 17703099; 17785434; 17943724; 18056706; 18067320; 18089558; 18174230; 18180382; 18267011; 18337055; 18564062; 18628988; 18710921; 18714047; 18842137; 18849153; 18922801; 18978678; 18991950; 19131339; 19258392; 19258394; 19290918; 19330793; 19468241; 19501919; 19542604; 19567819; 19690143; 19711372; 19728795; 19733625; 19805512; 19807924; 19816407; 19913121; 19917775; 19953087; 19955046; 19958149; 19968749; 20012528; 20056178; 20056645; 20151426; 20182632; 20360068; 20506281; 20534535; 20584982; 20628086; 20658524; 20682987; 20855525; 21098700; 21139048; 21298565; 21364031; 21371426; 21480388; 21513984; 21592972; 21642356; 21692989; 21738584; 21749309; 21757751; 21799250; 21881001; 21890473; 21900206; 21952639; 21963094; 21988832; 22161863; 22189847; 22354875; 22403409; 22422068; 22442244; 22447928; 22474169; 22653218; 22689581; 22709448; 22745667; 22833681; 22843238; 22868769; 22939624; 22987042; 23000965; 23077515; 23128233; 23175838; 23188823; 23250004; 23300847; 23438599; 23455924; 23497302; 23606749; 23918783; 24413734 FYN oncogene related to SRC, FGR, YES Ensembl:ENSG00000010810 HGNC:4037 HPRD:00655 MIM:137025 Vega:OTTHUMG00000016305 FYN Bin Zhao, Yue Liu, Oliver He GALNR GALNR1 WEB: http://www.ncbi.nlm.nih.gov/gene GALR1 galanin receptor 1 2587 18q23 20140408 9606 18 protein-coding Official from a nomenclature committee GO_0004966 (EC: IEA); GO_0005515 (EC: IPI); GO_0005886 (EC: TAS); GO_0007189 (EC: IEA); GO_0007194 (EC: IEA); GO_0007204 (EC: IEA); GO_0007218 (EC: TAS, PMID: 7524088); GO_0007586 (EC: TAS, PMID: 8670213); GO_0016021 (EC: IEA); GO_0042923 (EC: IEA) PMID: 2834384; 7524088; 7534460; 8617199; 8670213; 8825658; 9168941; 9367674; 9425310; 9808667; 12477932; 15767248; 15930442; 17083333; 17982695; 18385373; 18577758; 18973137; 19047085; 19086053; 19913121; 20171159; 20201926; 20398908; 20468064; 20628086; 21430647; 21796100; 22859720; 23251661; 23727823 galanin receptor 1 HGNC:4132 HPRD:02657 MIM:600377 GALR1 Bin Zhao, Yue Liu, Oliver He G3PD GAPD HEL-S-162eP WEB: http://www.ncbi.nlm.nih.gov/gene GAPDH glyceraldehyde-3-phosphate dehydrogenase 2597 CDABP0047 12p13 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000226 (EC: ISS); GO_0004365 (EC: ISS); GO_0004365 (EC: NAS, PMID: 3170585); GO_0005515 (EC: IPI, PMID: 11724794); GO_0005634 (EC: ISS); GO_0005737 (EC: IDA); GO_0005737 (EC: ISS); GO_0005811 (EC: IDA, PMID: 14741744); GO_0005829 (EC: ISS); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA); GO_0005975 (EC: TAS); GO_0006006 (EC: TAS); GO_0006094 (EC: TAS); GO_0006096 (EC: IEA); GO_0006096 (EC: TAS); GO_0008017 (EC: ISS); GO_0015630 (EC: ISS); GO_0017148 (EC: IDA); GO_0017148 (EC: IMP, PMID: 15479637); GO_0030529 (EC: IDA, PMID: 15479637); GO_0035605 (EC: ISS); GO_0035606 (EC: ISS); GO_0042802 (EC: IPI); GO_0044281 (EC: TAS); GO_0048471 (EC: IEA); GO_0050661 (EC: IEA); GO_0050821 (EC: ISS); GO_0051287 (EC: IEA); GO_0051402 (EC: ISS); GO_0070062 (EC: IDA, PMID: 11487543); GO_0071346 (EC: IDA, PMID: 15479637); GO_0097452 (EC: IDA, PMID: 15479637) PMID: 957435; 1193541; 1602151; 1924305; 1999197; 2394733; 2793178; 2987855; 3027061; 3170585; 3180054; 3664468; 6095107; 6096136; 6096821; 6499844; 7030790; 7498159; 7880402; 8075252; 8181459; 8451199; 8473906; 8612237; 8619474; 8650074; 8872471; 9110174; 9308888; 9886087; 10097256; 10407144; 10617673; 10897012; 10944468; 11011077; 11157717; 11451542; 11487543; 11488911; 11724794; 11735259; 11846445; 12008025; 12087577; 12121569; 12140138; 12200519; 12381782; 12419855; 12428732; 12477932; 12503091; 12506084; 12553051; 12665801; 12697324; 12753082; 12829261; 12842090; 12842822; 12887926; 12921788; 14515148; 14630908; 14730345; 14741744; 14760703; 15001839; 15047060; 15107835; 15161933; 15199064; 15312048; 15383276; 15479637; 15485821; 15489334; 15507493; 15592455; 15604093; 15628863; 15635413; 15673432; 15680915; 15716040; 15746184; 15769908; 15839736; 15852347; 15907785; 15951807; 15952740; 15976103; 15985219; 16027165; 16037232; 16055720; 16082386; 16139273; 16169070; 16186172; 16196087; 16236267; 16239728; 16263121; 16289162; 16396496; 16474839; 16492755; 16501887; 16510976; 16515701; 16682416; 16713569; 16751257; 16778134; 16799092; 16815975; 16832079; 16892178; 17015754; 17027006; 17081983; 17121833; 17324518; 17353931; 17373842; 17387692; 17456004; 17540579; 17540725; 17553795; 17597534; 17620599; 17955473; 17989880; 18029348; 18163542; 18206965; 18340469; 18362144; 18364388; 18448829; 18552833; 18624398; 18682386; 18708368; 18776186; 18776667; 18781797; 19001379; 19135240; 19156129; 19161537; 19165527; 19338310; 19380743; 19405953; 19430704; 19464723; 19596686; 19605696; 19621076; 19650766; 19738201; 19747091; 19800890; 19805454; 19837666; 19874799; 19940145; 20177150; 20181627; 20381070; 20407807; 20471030; 20610654; 20639865; 20664973; 20707929; 20727968; 20800603; 20849852; 20864222; 20972425; 21044950; 21073742; 21080425; 21110914; 21139048; 21145461; 21151833; 21163940; 21182205; 21236242; 21319273; 21336310; 21338575; 21539808; 21565611; 21749859; 21832049; 21853274; 21890473; 21895736; 21900206; 21906983; 21963094; 21979951; 21987572; 21988832; 22053931; 22079093; 22174317; 22178446; 22189680; 22268729; 22304920; 22350014; 22505724; 22534308; 22536838; 22613203; 22623428; 22789853; 22847419; 22863883; 22939629; 22957700; 22963082; 22964641; 22990118; 23000965; 23027902; 23077236; 23086952; 23091630; 23237566; 23332158; 23348613; 23402259; 23409959; 23428871; 23455922; 23463506; 23527007; 23602568; 23620736; 23645209; 23750785; 23798571; 23956138; 24113185; 24244333; 24457600 glyceraldehyde-3-phosphate dehydrogenase Ensembl:ENSG00000111640 HGNC:4141 HPRD:00713 MIM:138400 Vega:OTTHUMG00000137379 GAPDH Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene GAS1 growth arrest-specific 1 2619 9q21.3-q22 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0002053 (EC: IEA); GO_0005515 (EC: IPI); GO_0005886 (EC: IDA, PMID: 8127893); GO_0007050 (EC: IEA); GO_0007411 (EC: IEA); GO_0008589 (EC: ISS); GO_0010955 (EC: IMP); GO_0012501 (EC: IEA); GO_0016021 (EC: NAS, PMID: 8127893); GO_0021587 (EC: IEA); GO_0021904 (EC: IEA); GO_0030308 (EC: IEA); GO_0035924 (EC: IEP, PMID: 15070677); GO_0042473 (EC: IEA); GO_0042474 (EC: IEA); GO_0042476 (EC: IEA); GO_0042733 (EC: IEA); GO_0042981 (EC: ISS); GO_0043010 (EC: IEA); GO_0043066 (EC: IEA); GO_0045165 (EC: ISS); GO_0045879 (EC: IEA); GO_0045880 (EC: IEA); GO_0045930 (EC: IDA, PMID: 8127893); GO_0045930 (EC: IGI, PMID: 11356029); GO_0046658 (EC: ISS); GO_0048589 (EC: ISS); GO_0048592 (EC: IEA); GO_0048701 (EC: IEA); GO_0050679 (EC: IEA); GO_0050680 (EC: IEA); GO_0060021 (EC: IEA); GO_0060628 (EC: IMP); GO_2001240 (EC: IEA) PMID: 1505026; 7956349; 8127893; 8307588; 8889548; 9466658; 10996315; 11356029; 11572986; 11846389; 11906213; 12477932; 15070677; 15103018; 16551639; 17726382; 18394855; 18981472; 19322201; 19460624; 19638344; 20050020; 20583177; 20628624; 21111449; 21357679; 21842183; 21890473; 21901158; 21971401; 22311470; 22846196; 23254899 growth arrest-specific 1 GAS1 Bin Zhao, Yue Liu, Oliver He 1A GDIL MRX41 MRX48 OPHN2 RABGD1A RABGDIA XAP-4 WEB: http://www.ncbi.nlm.nih.gov/gene GDI1 GDP dissociation inhibitor 1 2664 XX-FW81657B9.1 Xq28 20140408 9606 X protein-coding Official from a nomenclature committee GO_0005092 (EC: TAS, PMID: 7849400); GO_0005093 (EC: ISS); GO_0005096 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11809807); GO_0005737 (EC: IDA); GO_0005794 (EC: IEA); GO_0005829 (EC: TAS); GO_0007165 (EC: TAS, PMID: 7543319); GO_0007264 (EC: TAS); GO_0015031 (EC: IEA); GO_0017137 (EC: IEA); GO_0030496 (EC: IDA, PMID: 15166316); GO_0032482 (EC: ISS); GO_0043005 (EC: IEA); GO_0043234 (EC: IEA); GO_0050771 (EC: ISS); GO_0050790 (EC: ISS); GO_0050790 (EC: TAS, PMID: 7849400); GO_0051056 (EC: TAS); GO_0051592 (EC: IEA); GO_0090315 (EC: IMP) PMID: 1286667; 2115118; 7513052; 7543319; 7585614; 7744738; 7849400; 8175798; 8248200; 8281148; 8491184; 8733135; 8826463; 8836150; 9106537; 9490022; 9620768; 9668174; 9674910; 10751420; 11076863; 11256614; 11583574; 11741295; 11809807; 12198156; 12477932; 12777533; 12802062; 14702039; 15166316; 15292224; 15480879; 15489334; 15489336; 15592455; 15647276; 16344560; 16368544; 16381901; 16596196; 16713569; 17353931; 17568003; 18255255; 18487148; 19570034; 19996123; 20381070; 20562859; 21139048; 21145461; 21319273; 21565611; 21736009; 21890473; 21900206; 21906983; 21963094; 21987572; 22002931; 22053931; 22114354; 22505724; 22586326; 22863883; 22939629; 23000965; 23140504 GDP dissociation inhibitor 1 Ensembl:ENSG00000203879 HGNC:4226 HPRD:02114 MIM:300104 Vega:OTTHUMG00000033293 GDI1 Bin Zhao, Yue Liu, Oliver He HEL-S-46e RABGDIB WEB: http://www.ncbi.nlm.nih.gov/gene GDI2 GDP dissociation inhibitor 2 2665 RP11-318E3.2 10p15 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0005093 (EC: IEA); GO_0005097 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11809807); GO_0005737 (EC: TAS, PMID: 16130169); GO_0005794 (EC: IEA); GO_0005829 (EC: TAS); GO_0007165 (EC: TAS, PMID: 16130169); GO_0007264 (EC: TAS); GO_0015031 (EC: IEA); GO_0016020 (EC: IEA); GO_0044822 (EC: IDA); GO_0051056 (EC: TAS); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 7513052; 7543319; 7585614; 7929030; 8575461; 9434952; 10512627; 10996854; 11771757; 11809807; 12477932; 12493773; 14702039; 15489334; 16009940; 16130169; 16344560; 16385451; 17507299; 18781797; 19056867; 19135240; 19322201; 19570034; 19738201; 20360068; 20562859; 21139048; 21565611; 21890473; 21906983; 21963094; 21987572; 21988832; 22053931; 22505724; 22586326; 22863883; 22939629; 23000965; 23184937; 23727862; 23824909 GDP dissociation inhibitor 2 Ensembl:ENSG00000057608 HGNC:4227 HPRD:02863 MIM:600767 Vega:OTTHUMG00000017607 GDI2 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene GFAP glial fibrillary acidic protein 2670 17q21 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0005178 (EC: IEA); GO_0005200 (EC: IEA); GO_0005737 (EC: IDA, PMID: 12355421); GO_0005829 (EC: TAS); GO_0005882 (EC: IEA); GO_0009611 (EC: IEA); GO_0010625 (EC: IEA); GO_0010977 (EC: IEA); GO_0014002 (EC: IEA); GO_0016020 (EC: IEA); GO_0019900 (EC: IEA); GO_0030198 (EC: IEA); GO_0031102 (EC: IEA); GO_0044297 (EC: IEA); GO_0045109 (EC: IEA); GO_0051580 (EC: IEA); GO_0060020 (EC: IEA); GO_0060291 (EC: IEA); GO_0097449 (EC: IEA) PMID: 1601131; 1602151; 1636374; 1847665; 1918004; 2114109; 2155236; 2163003; 2201025; 2349237; 2740350; 2780570; 7822264; 7842474; 7964717; 8125298; 8318270; 8381971; 8889548; 9099667; 9417904; 9693047; 10510252; 10597774; 11138011; 11379820; 11519482; 11567214; 11587071; 11595337; 11867077; 11891800; 12034796; 12058025; 12084347; 12169273; 12177195; 12355421; 12447932; 12477932; 12581808; 12686604; 12771190; 12837269; 12884016; 12931206; 12944715; 12975300; 14557587; 14702039; 15174051; 15238995; 15284230; 15285794; 15465095; 15469203; 15477559; 15489334; 15519244; 15732097; 15837555; 15839736; 15885920; 15979880; 16147953; 16168593; 16168595; 16189514; 16217707; 16303762; 16344560; 16365790; 16458536; 16507904; 16507909; 16565071; 16773221; 16826512; 16866629; 17008879; 17077296; 17203480; 17318298; 17500595; 17515952; 17590381; 17601350; 17703343; 17805552; 17894839; 17934883; 17981838; 17985264; 18004641; 18054694; 18079314; 18197187; 18239623; 18276609; 18508349; 18685083; 18977241; 19019082; 19034380; 19110265; 19129171; 19170683; 19221847; 19264642; 19283393; 19372295; 19379794; 19405953; 19420941; 19427371; 19444543; 19447584; 19508443; 19521276; 19540848; 19618846; 19647039; 19663312; 19668151; 19686046; 19878567; 19886840; 19888461; 20048155; 20121722; 20301351; 20471030; 20473970; 20578042; 20625342; 20721574; 20849398; 20886841; 20936779; 20942581; 21075782; 21079180; 21197541; 21368691; 21702960; 21756903; 21779366; 21832049; 21876753; 21917775; 21976236; 21987397; 21988832; 22118268; 22206859; 22318658; 22360420; 22410258; 22488673; 22492246; 22797925; 22985558; 23321059; 23364391; 23371454; 23392373; 23418544; 23455922; 23594359; 23624779; 23626774; 23634874; 23743246; 23746601; 23826164; 23827424; 23903069; 24045243 glial fibrillary acidic protein GFAP Bin Zhao, Yue Liu, Oliver He CMSTA1 GFA GFAT GFAT 1 GFAT1 GFAT1m GFPT GFPT1L MSLG WEB: http://www.ncbi.nlm.nih.gov/gene GFPT1 glutamine--fructose-6-phosphate transaminase 1 2673 2p13 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0004360 (EC: IEA); GO_0005829 (EC: TAS); GO_0006002 (EC: IEA); GO_0006042 (EC: IEA); GO_0006048 (EC: IEA); GO_0006048 (EC: TAS); GO_0006112 (EC: TAS, PMID: 1460020); GO_0006488 (EC: TAS); GO_0006541 (EC: IEA); GO_0006987 (EC: TAS); GO_0009744 (EC: IEA); GO_0016051 (EC: IEA); GO_0016597 (EC: IEA); GO_0018279 (EC: TAS); GO_0030246 (EC: IEA); GO_0030968 (EC: TAS); GO_0032869 (EC: IEA); GO_0032922 (EC: ISS); GO_0043687 (EC: TAS); GO_0044267 (EC: TAS); GO_0045719 (EC: IEA); GO_0051289 (EC: IEA); GO_0070062 (EC: IDA) PMID: 1460020; 2037571; 7601477; 7607664; 8144040; 8619474; 9110174; 9519709; 10198162; 10806197; 10997685; 11587069; 11679416; 12477932; 12802498; 14988277; 15308130; 15489334; 15595739; 15613432; 15878746; 16341674; 16344560; 16964243; 17024311; 17081983; 17542649; 17941647; 18781797; 19059404; 19170765; 19322201; 20301347; 20562859; 20845477; 21139048; 21310273; 21890473; 21906983; 21988832; 22053931; 22505724; 22586326; 22863883; 22987706; 23000965; 23569079; 23794683; 24250222 glutamine--fructose-6-phosphate transaminase 1 Ensembl:ENSG00000198380 HGNC:4241 HPRD:00702 MIM:138292 Vega:OTTHUMG00000152666 GFPT1 Bin Zhao, Yue Liu, Oliver He EBP ELNR1 MPS4B WEB: http://www.ncbi.nlm.nih.gov/gene GLB1 galactosidase, beta 1 2720 3p21.33 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0004565 (EC: TAS, PMID: 3143362); GO_0005515 (EC: IPI, PMID: 15498789); GO_0005737 (EC: IDA); GO_0005794 (EC: IDA); GO_0005975 (EC: TAS); GO_0006027 (EC: TAS); GO_0006665 (EC: TAS); GO_0006687 (EC: TAS); GO_0016936 (EC: IEA); GO_0019388 (EC: IEA); GO_0030203 (EC: TAS); GO_0042339 (EC: TAS); GO_0042340 (EC: TAS); GO_0043202 (EC: TAS); GO_0044281 (EC: TAS); GO_0048471 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 110522; 113895; 1353343; 1487238; 1606711; 1907800; 1909089; 1909871; 1928092; 2111707; 2511208; 3084469; 3102233; 3143362; 3921454; 3922758; 6791574; 6807121; 7586649; 7693577; 8125298; 8198123; 8199591; 8213816; 8383699; 8500799; 8670798; 8910459; 8922281; 9203065; 9497360; 9501080; 10338095; 10571006; 10737981; 10839995; 10841810; 10891505; 11511921; 12393180; 12477932; 12515396; 12644936; 14987258; 15365997; 15489334; 15498789; 15714521; 15907791; 16263699; 16314420; 16314480; 16344560; 16538002; 16626397; 16941474; 17309651; 17353931; 17522702; 17661814; 17664528; 18088383; 18217416; 18353697; 18524657; 18704747; 18772331; 18976701; 19056867; 19091613; 19472408; 19769716; 20000738; 20175788; 20379614; 20826101; 20920281; 20947500; 21105107; 21139048; 21321400; 21890473; 21900206; 21906983; 21963094; 21978926; 21988832; 22001501; 22033734; 22128166; 22178079; 22234367; 22268729; 22763966; 22908062; 23042114; 24156116; 24250222 galactosidase, beta 1 Ensembl:ENSG00000170266 HGNC:4298 HPRD:01975 MIM:611458 Vega:OTTHUMG00000155781 GLB1 Bin Zhao, Yue Liu, Oliver He CMC1 G-ALPHA-q GAQ SWS WEB: http://www.ncbi.nlm.nih.gov/gene GNAQ guanine nucleotide binding protein (G protein), q polypeptide 2776 RP11-494N1.1 9q21 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0001501 (EC: IEA); GO_0001508 (EC: IBA); GO_0001664 (EC: IBA); GO_0003924 (EC: IEA); GO_0004871 (EC: IBA); GO_0005096 (EC: IDA, PMID: 15611106); GO_0005515 (EC: IPI, PMID: 18672896); GO_0005525 (EC: IEA); GO_0005737 (EC: TAS, PMID: 9175863); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005834 (EC: IBA); GO_0005886 (EC: TAS); GO_0006469 (EC: IMP); GO_0007189 (EC: IBA); GO_0007202 (EC: TAS, PMID: 8825633); GO_0007215 (EC: IBA); GO_0007507 (EC: IEA); GO_0007596 (EC: TAS); GO_0009791 (EC: IEA); GO_0016322 (EC: IEA); GO_0021884 (EC: IEA); GO_0030168 (EC: TAS); GO_0031234 (EC: IBA); GO_0031683 (EC: IBA); GO_0031965 (EC: IEA); GO_0035412 (EC: IMP); GO_0042711 (EC: IEA); GO_0042733 (EC: IEA); GO_0043547 (EC: IDA, PMID: 15611106); GO_0045634 (EC: IEA); GO_0046872 (EC: IEA); GO_0048066 (EC: IEA); GO_0050821 (EC: IMP); GO_0060158 (EC: IBA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1322796; 1333286; 1851174; 2841328; 7492305; 7629074; 7791744; 7937899; 8188646; 8227063; 8504751; 8552586; 8655576; 8664309; 8825633; 8836152; 8863838; 8923415; 8982657; 9061052; 9152406; 9175863; 9198220; 9238049; 9405622; 9481484; 9488690; 9660808; 9685625; 9700850; 9770463; 10446129; 10488065; 10550060; 10598591; 10633085; 10728414; 11076863; 11118617; 11194358; 11253162; 11278452; 11375483; 11408001; 11443126; 11686331; 11753430; 11812005; 11848441; 11875076; 11895442; 11916537; 11955952; 11981043; 12016230; 12130679; 12193606; 12399457; 12477932; 12496284; 12509430; 12626493; 12629551; 12650852; 12652642; 12670932; 12670961; 12704201; 12711604; 12714438; 12726995; 12748287; 12807915; 12885252; 14561750; 14617636; 14634662; 14702039; 15115661; 15134434; 15251452; 15322542; 15383626; 15466861; 15471870; 15489336; 15611106; 15694379; 15698833; 15735747; 15782186; 15794946; 16038796; 16102047; 16218966; 16381901; 16481068; 16629901; 16650966; 16860758; 16893886; 16995904; 17197445; 17255364; 17307333; 17498700; 17535809; 17552882; 17606614; 17720980; 17846866; 17897319; 18096806; 18240029; 18322150; 18326504; 18424071; 18434368; 18514160; 18577758; 18632858; 18672896; 18719078; 18851832; 18936096; 18989526; 18991294; 19056867; 19074439; 19074441; 19078957; 19332487; 19426503; 19445628; 19551532; 19654573; 19718445; 19903011; 19936769; 20007712; 20133939; 20237586; 20379146; 20399743; 20562673; 20590159; 20631239; 20664004; 20714830; 20805136; 20865267; 21056896; 21072599; 21083380; 21139048; 21304157; 21366456; 21464134; 21487925; 21515378; 21592972; 21906983; 21940795; 21945171; 21963094; 21988832; 22056876; 22253748; 22307269; 22701657; 22710260; 22758774; 22905097; 22939629; 22977135; 23066026; 23159116; 23315865; 23572068; 23572156; 23634288; 23656586; 23665327; 23685997; 23778528; 23884432 guanine nucleotide binding protein (G protein), q polypeptide HGNC:4390 HPRD:02998 MIM:600998 GNAQ Bin Zhao, Yue Liu, Oliver He ASTQTL1 GIG18 cAspAT cCAT WEB: http://www.ncbi.nlm.nih.gov/gene GOT1 glutamic-oxaloacetic transaminase 1, soluble 2805 10q24.1-q25.1 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0000096 (EC: TAS); GO_0004069 (EC: IDA, PMID: 2182221); GO_0004069 (EC: ISS); GO_0004069 (EC: TAS); GO_0004609 (EC: IEA); GO_0005737 (EC: IDA, PMID: 7060339); GO_0005764 (EC: IEA); GO_0005829 (EC: TAS); GO_0005975 (EC: TAS); GO_0006006 (EC: TAS); GO_0006094 (EC: TAS); GO_0006103 (EC: ISS); GO_0006107 (EC: IEA); GO_0006114 (EC: ISS); GO_0006531 (EC: ISS); GO_0006532 (EC: IEA); GO_0006533 (EC: IDA, PMID: 2241899); GO_0006536 (EC: ISS); GO_0006595 (EC: TAS); GO_0008483 (EC: TAS); GO_0008652 (EC: TAS); GO_0019509 (EC: TAS); GO_0019550 (EC: IEA); GO_0019551 (EC: IEA); GO_0030170 (EC: IEA); GO_0031406 (EC: IEA); GO_0032869 (EC: IEP, PMID: 8396422); GO_0034641 (EC: TAS); GO_0043679 (EC: IEA); GO_0044281 (EC: TAS); GO_0047801 (EC: ISS); GO_0051384 (EC: IEP, PMID: 8396422); GO_0055089 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0080130 (EC: IEA) PMID: 225064; 1974457; 2182221; 2225456; 2241899; 2731362; 2777255; 3207426; 6391741; 6397370; 7060339; 8349677; 8396422; 8619474; 9110174; 10360399; 12477932; 12480555; 15164054; 15306699; 15489334; 16169070; 16344560; 16681433; 17623298; 17877759; 17907318; 18242760; 18752324; 19012630; 19056867; 19370784; 19393479; 20029029; 20201926; 20205615; 20499337; 20972737; 21139048; 21750724; 21900944; 21906983; 21963094; 21988832; 22132177; 22242166; 22352690; 22412388; 22863883; 23667618; 24124411 glutamic-oxaloacetic transaminase 1, soluble Ensembl:ENSG00000120053 HGNC:4432 HPRD:00687 MIM:138180 Vega:OTTHUMG00000018882 GOT1 Bin Zhao, Yue Liu, Oliver He KAT4 KATIV mitAAT WEB: http://www.ncbi.nlm.nih.gov/gene GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 2806 16q21 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0004069 (EC: EXP); GO_0004069 (EC: IDA, PMID: 2182221); GO_0004069 (EC: ISS); GO_0005739 (EC: IDA); GO_0005739 (EC: ISS); GO_0005743 (EC: IEA); GO_0005759 (EC: TAS); GO_0005886 (EC: IDA, PMID: 9537447); GO_0005975 (EC: TAS); GO_0006006 (EC: TAS); GO_0006094 (EC: TAS); GO_0006103 (EC: ISS); GO_0006107 (EC: IEA); GO_0006531 (EC: ISS); GO_0006532 (EC: IEA); GO_0006533 (EC: IDA, PMID: 2567216); GO_0006536 (EC: ISS); GO_0008652 (EC: TAS); GO_0015908 (EC: IEP, PMID: 9537447); GO_0016212 (EC: IEA); GO_0019470 (EC: TAS); GO_0019550 (EC: IEA); GO_0019551 (EC: IEA); GO_0030170 (EC: IEA); GO_0034641 (EC: TAS); GO_0044281 (EC: TAS); GO_0044822 (EC: IDA); GO_0045471 (EC: IDA, PMID: 9537447); GO_0070062 (EC: IDA); GO_0080130 (EC: IEA) PMID: 376500; 752471; 2182221; 2567216; 2731362; 2777255; 2899080; 3207426; 3997814; 4052435; 5450376; 6397370; 6930651; 7114792; 7225087; 7559589; 8125298; 8349677; 9537447; 12477932; 12601813; 14702039; 15489334; 16169070; 16212419; 17353931; 17442055; 17728674; 17877759; 18781797; 19305408; 19834535; 20360068; 20877624; 21081666; 21139048; 21223598; 21319273; 21890473; 21900206; 21906983; 21963094; 22713574; 23000965 glutamic-oxaloacetic transaminase 2, mitochondrial Ensembl:ENSG00000125166 HGNC:4433 HPRD:00684 MIM:138150 Vega:OTTHUMG00000133769 GOT2 Bin Zhao, Yue Liu, Oliver He AMF GNPI NLK PGI PHI SA-36 SA36 WEB: http://www.ncbi.nlm.nih.gov/gene GPI glucose-6-phosphate isomerase 2821 19q13.1 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0001525 (EC: IEA); GO_0004347 (EC: TAS); GO_0005125 (EC: IEA); GO_0005615 (EC: IEA); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA); GO_0005975 (EC: TAS); GO_0006006 (EC: TAS); GO_0006094 (EC: TAS); GO_0006096 (EC: IEA); GO_0006096 (EC: TAS); GO_0006959 (EC: TAS, PMID: 3020690); GO_0007599 (EC: TAS, PMID: 7435496); GO_0007611 (EC: IEA); GO_0008083 (EC: IEA); GO_0016866 (EC: IEA); GO_0019242 (EC: IEA); GO_0043005 (EC: IEA); GO_0043154 (EC: IEA); GO_0043524 (EC: IEA); GO_0044281 (EC: TAS); GO_0046185 (EC: IEA); GO_0048029 (EC: IEA); GO_0051156 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 2387591; 2544027; 2547084; 3020690; 3352745; 7435496; 7545951; 7989588; 8499925; 8575767; 8822952; 8822954; 8889548; 9446754; 9616041; 9856489; 10216265; 10727272; 10916680; 11004567; 11264592; 11418246; 11431735; 11688991; 11896391; 11896393; 12054796; 12477932; 12517804; 12527360; 12573240; 12737943; 12783864; 14566819; 14715248; 15034067; 15059907; 15290745; 15369782; 15489334; 15570012; 15576338; 15637053; 15850830; 16009940; 16196087; 16563432; 16949042; 17041899; 17071500; 17690101; 17875708; 17925402; 18029348; 18311788; 18485900; 18781797; 18992137; 19056867; 19064002; 19531650; 19787266; 19801670; 19819066; 20237496; 20360068; 20810510; 20845477; 20849852; 20978190; 21139048; 21252914; 21319273; 21555518; 21890473; 21906983; 21963094; 21970785; 21987572; 22053931; 22261722; 22360420; 22505724; 22939629; 23000965; 23248119; 23773638; 23824909 glucose-6-phosphate isomerase Ensembl:ENSG00000105220 HGNC:4458 HPRD:01394 MIM:172400 Vega:OTTHUMG00000182087 GPI Bin Zhao, Yue Liu, Oliver He CD182 CD183 CKR-L2 CMKAR3 GPR9 IP10-R Mig-R MigR WEB: http://www.ncbi.nlm.nih.gov/gene CXCR3 chemokine (C-X-C motif) receptor 3 2833 Xq13 20140408 9606 X protein-coding Official from a nomenclature committee GO_0001525 (EC: IEA); GO_0001937 (EC: IDA, PMID: 12782716); GO_0002685 (EC: IEA); GO_0004872 (EC: IDA, PMID: 12782716); GO_0004950 (EC: TAS, PMID: 9064356); GO_0005737 (EC: TAS, PMID: 10903743); GO_0005886 (EC: IDA, PMID: 12782716); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 9064356); GO_0006915 (EC: IEA); GO_0006928 (EC: TAS, PMID: 10741397); GO_0006935 (EC: TAS, PMID: 10903763); GO_0006954 (EC: IEA); GO_0007155 (EC: TAS, PMID: 10942362); GO_0007166 (EC: IDA, PMID: 11554781); GO_0007186 (EC: IMP, PMID: 12782716); GO_0007204 (EC: IEA); GO_0008284 (EC: IDA, PMID: 12782716); GO_0009897 (EC: IEA); GO_0010818 (EC: IEA); GO_0016494 (EC: IEA); GO_0016525 (EC: IDA, PMID: 12782716); GO_0019722 (EC: IEA); GO_0019956 (EC: IPI, PMID: 11554781); GO_0019958 (EC: IDA, PMID: 12782716); GO_0030816 (EC: IDA, PMID: 12782716); GO_0043950 (EC: IDA, PMID: 12782716); GO_0045766 (EC: IDA, PMID: 12782716); GO_0045944 (EC: IDA, PMID: 12782716); GO_0050921 (EC: IDA, PMID: 12782716); GO_0051281 (EC: IMP, PMID: 12782716); GO_0071954 (EC: IDA, PMID: 12782716); GO_1900118 (EC: IDA, PMID: 12782716); GO_1900119 (EC: IDA, PMID: 12782716) PMID: 2834384; 8666380; 9064356; 9419219; 9466968; 9625760; 9660793; 10233762; 10393705; 10627472; 10666479; 10741397; 10900358; 10903743; 10903763; 10942362; 11083865; 11134180; 11160352; 11196695; 11554781; 11559369; 11714650; 11739530; 11966764; 11990865; 12016104; 12055238; 12070001; 12097412; 12270371; 12356205; 12425561; 12444109; 12445801; 12477932; 12517959; 12571234; 12688353; 12750173; 12782716; 12819030; 12884299; 12919091; 12953097; 12960247; 12960302; 14578618; 14618028; 14630801; 14657006; 14742268; 15126579; 15150261; 15155273; 15181567; 15254596; 15265234; 15273303; 15328188; 15489334; 15501397; 15518810; 15528361; 15578697; 15687242; 15713799; 15725351; 15808644; 15843529; 15856455; 15879427; 15885315; 16033640; 16034118; 16043121; 16127166; 16243485; 16339779; 16368892; 16455991; 16456020; 16679918; 16733654; 16787707; 16806233; 16847335; 16861617; 16930533; 16934957; 17018607; 17142783; 17142784; 17251291; 17339184; 17363734; 17457216; 17560677; 17615381; 17666357; 17703412; 17912012; 17947699; 18037659; 18174362; 18240029; 18280341; 18291705; 18375741; 18453591; 18485912; 18497951; 18616679; 18689270; 18729739; 18761554; 18798334; 18832436; 18962861; 19017998; 19106589; 19134328; 19232748; 19258923; 19344719; 19380511; 19539215; 19641142; 19703720; 19734217; 19735481; 19758167; 19767105; 19800124; 20041963; 20047517; 20059481; 20079227; 20096889; 20164417; 20185576; 20203286; 20228225; 20237496; 20377416; 20379873; 20429924; 20485444; 20503287; 20529825; 20733031; 20848514; 20855888; 20856926; 20980681; 21051441; 21087446; 21091908; 21148743; 21255008; 21274647; 21303425; 21303517; 21357438; 21426802; 21538345; 21645215; 21739422; 21811993; 21962843; 22079021; 22111598; 22236567; 22262158; 22369302; 22392992; 22401929; 22675496; 22685032; 22689289; 22792160; 22796894; 22798340; 22936405; 23121557; 23158864; 23179902; 23298254; 23600831; 23643635; 24129241; 24135023 chemokine (C-X-C motif) receptor 3 Ensembl:ENSG00000186810 HGNC:4540 HPRD:02936 MIM:300574 Vega:OTTHUMG00000033326 CXCR3 Bin Zhao, Yue Liu, Oliver He GPXD GSHPX1 WEB: http://www.ncbi.nlm.nih.gov/gene GPX1 glutathione peroxidase 1 2876 3p21.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0001659 (EC: IEA); GO_0001885 (EC: IEA); GO_0002862 (EC: IEA); GO_0004602 (EC: IDA, PMID: 12829378); GO_0004602 (EC: TAS); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA); GO_0005739 (EC: IDA, PMID: 10833429); GO_0005759 (EC: TAS); GO_0005829 (EC: TAS); GO_0006144 (EC: TAS); GO_0006195 (EC: TAS); GO_0006641 (EC: IEA); GO_0006749 (EC: IDA, PMID: 12829378); GO_0006982 (EC: IEA); GO_0007568 (EC: IEA); GO_0007605 (EC: IEA); GO_0008430 (EC: IEA); GO_0008631 (EC: IEA); GO_0009410 (EC: IEA); GO_0009609 (EC: IEA); GO_0009636 (EC: IEA); GO_0009650 (EC: IMP, PMID: 17097614); GO_0009749 (EC: IEA); GO_0010269 (EC: IMP, PMID: 12810669); GO_0010332 (EC: IEA); GO_0017124 (EC: IPI, PMID: 12893824); GO_0018158 (EC: IEA); GO_0019369 (EC: TAS); GO_0019372 (EC: TAS); GO_0032355 (EC: IEA); GO_0033599 (EC: IMP, PMID: 16945136); GO_0035094 (EC: IEA); GO_0040029 (EC: IDA, PMID: 16132718); GO_0042311 (EC: IEA); GO_0042542 (EC: IMP, PMID: 12829378); GO_0042744 (EC: IDA, PMID: 15203190); GO_0043066 (EC: IEA); GO_0043154 (EC: IMP, PMID: 12221075); GO_0043295 (EC: IEA); GO_0043403 (EC: IEA); GO_0043523 (EC: IEA); GO_0043534 (EC: IEA); GO_0044281 (EC: TAS); GO_0045444 (EC: IEA); GO_0045454 (EC: IDA, PMID: 12829378); GO_0047066 (EC: IEA); GO_0048741 (EC: IEA); GO_0051450 (EC: IEA); GO_0051593 (EC: IEA); GO_0051702 (EC: IEA); GO_0051897 (EC: IEA); GO_0055086 (EC: TAS); GO_0060047 (EC: IMP, PMID: 14573732); GO_0060055 (EC: IEA); GO_0061136 (EC: IDA, PMID: 12751788); GO_0090201 (EC: IMP, PMID: 12221075); GO_1902042 (EC: IMP, PMID: 12221075); GO_1902176 (EC: IEA) PMID: 1556108; 2307470; 2955287; 2976939; 3658677; 3697069; 8001233; 8125298; 8428933; 9126277; 9501919; 9605859; 10220143; 10652368; 10833429; 10880344; 11103801; 11112379; 11368344; 11823528; 12221075; 12447480; 12470500; 12477932; 12496980; 12531513; 12655278; 12732844; 12751788; 12787913; 12810669; 12829378; 12832449; 12893824; 12893830; 14573732; 14671197; 14744747; 14962293; 14962975; 15125229; 15149466; 15167446; 15192016; 15203190; 15247771; 15295091; 15298967; 15318035; 15331559; 15489334; 15774926; 15829318; 15878749; 15910762; 15946795; 15990458; 16132718; 16230136; 16287877; 16354666; 16413612; 16424062; 16523188; 16538174; 16543247; 16614101; 16615267; 16627788; 16797832; 16868544; 16871233; 16945136; 16956821; 16979635; 17052796; 17097614; 17149600; 17171548; 17275003; 17334644; 17336361; 17526193; 17548672; 17601350; 17625244; 17634480; 17693525; 17825092; 17850515; 18186040; 18267129; 18298806; 18417962; 18449862; 18469277; 18483336; 18541150; 18541588; 18563616; 18600213; 18676680; 18806750; 18853169; 18940188; 18977241; 19012493; 19026164; 19035188; 19056482; 19124506; 19125369; 19161995; 19170196; 19195504; 19195803; 19228881; 19254950; 19285650; 19347979; 19415410; 19423521; 19424819; 19428376; 19428448; 19488773; 19505917; 19527700; 19560448; 19573080; 19578796; 19625176; 19692168; 19705749; 19733578; 19773279; 19819955; 19826042; 19896490; 19913121; 19929244; 19944066; 19946932; 19949914; 19951064; 20041472; 20082261; 20097730; 20109103; 20178852; 20200426; 20219985; 20301895; 20303587; 20306294; 20307617; 20378690; 20441054; 20444272; 20471990; 20477822; 20480816; 20530237; 20578157; 20628086; 20643115; 20644561; 20724907; 20727719; 20802378; 20813000; 20851292; 20852007; 20877264; 20877624; 20878976; 21045266; 21048031; 21052528; 21053180; 21055077; 21087145; 21102463; 21165435; 21185702; 21292323; 21434422; 21586620; 21636625; 21842217; 21852236; 21900206; 21904836; 21921984; 21936966; 21989715; 21993316; 22036626; 22072582; 22167619; 22180033; 22259188; 22448134; 22556393; 22561328; 22645453; 22677746; 22683538; 22699881; 22704671; 22790458; 22843889; 22863883; 22888637; 22890915; 22951908; 22952184; 22964634; 23010849; 23063346; 23073788; 23128233; 23152058; 23212700; 23261989; 23289525; 23518201; 23590304; 23721877; 23725507; 23748877; 23837478; 23975365; 24037914; 24597264 glutathione peroxidase 1 Ensembl:ENSG00000233276 HGNC:4553 HPRD:11749 MIM:138320 Vega:OTTHUMG00000156837 GPX1 Bin Zhao, Yue Liu, Oliver He CLN11 GEP GP88 PCDGF PEPI PGRN WEB: http://www.ncbi.nlm.nih.gov/gene GRN granulin 2896 17q21.32 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0001835 (EC: IEA); GO_0005125 (EC: IEA); GO_0005515 (EC: IPI); GO_0005615 (EC: IEA); GO_0005739 (EC: IEA); GO_0007165 (EC: NAS, PMID: 1542665); GO_0007566 (EC: IEA); GO_0008083 (EC: TAS, PMID: 1542665); GO_0008219 (EC: IEA); GO_0043231 (EC: IDA); GO_0044822 (EC: IDA); GO_0050679 (EC: IEA) PMID: 1417868; 1542665; 1618805; 2268320; 8125298; 8471244; 8471426; 8496151; 8619474; 8912679; 9110174; 9826678; 10079180; 10397269; 10477733; 10715107; 10728698; 11068878; 11549288; 11846389; 12031912; 12477932; 12526812; 12538450; 12588988; 12900424; 12914763; 12931033; 14652816; 14702039; 14977833; 15231748; 15489334; 15569995; 15653695; 16189514; 16533762; 16713569; 16857791; 16862115; 16862116; 16950801; 16983677; 16983685; 17110338; 17157414; 17166276; 17202431; 17210807; 17228326; 17261172; 17266030; 17278999; 17291356; 17345602; 17353379; 17371905; 17383054; 17417739; 17436289; 17439980; 17458552; 17522386; 17572900; 17620546; 17698705; 17826340; 17949857; 17950702; 17984093; 18029348; 18157829; 18166610; 18183624; 18184915; 18192287; 18223198; 18234697; 18245784; 18276110; 18314228; 18322394; 18359860; 18378771; 18392865; 18413467; 18413474; 18442119; 18464284; 18479928; 18543312; 18551524; 18565828; 18593276; 18654987; 18706200; 18723384; 18723524; 18752597; 18768919; 18771956; 18838661; 18848708; 18855025; 18955727; 19012866; 19016491; 19020205; 19049508; 19056610; 19091059; 19101631; 19133655; 19158106; 19179604; 19237611; 19255408; 19321167; 19343720; 19446372; 19473366; 19487464; 19618231; 19625741; 19632744; 19649643; 19730170; 19730171; 19795409; 19847305; 19858458; 19863344; 19864668; 19913121; 19938685; 19940479; 19963041; 20020531; 20028451; 20045477; 20054825; 20061636; 20087814; 20142524; 20142525; 20154673; 20171924; 20197700; 20215705; 20237496; 20301545; 20301601; 20387302; 20463744; 20479936; 20489155; 20570546; 20628086; 20682318; 20711061; 20798611; 20858962; 20884628; 20930269; 20930271; 20933034; 20947212; 20975516; 21047645; 21078624; 21085476; 21087763; 21107132; 21123963; 21178100; 21204008; 21212639; 21224065; 21232819; 21258152; 21263192; 21289198; 21319273; 21393509; 21454553; 21482928; 21645364; 21677378; 21707777; 21753165; 21800185; 21802097; 21813674; 21891865; 21891869; 21892962; 21942715; 21988832; 22032330; 22045426; 22068162; 22088468; 22127750; 22130207; 22176685; 22194816; 22204653; 22268729; 22280948; 22316048; 22338605; 22348647; 22366795; 22397762; 22491866; 22504418; 22505994; 22509390; 22608501; 22623979; 22647257; 22665040; 22761921; 22787763; 22792281; 22797721; 22802426; 22819134; 22859297; 22890097; 22890101; 22945272; 22986778; 23088713; 23158232; 23218900; 23236149; 23317568; 23338682; 23342160; 23364791; 23396349; 23402259; 23409033; 23419701; 23455922; 23476101; 23478307; 23596077; 23609919; 23684369; 23702100; 24005336; 24070898; 24081456; 24163370; 24186875; 24457600 granulin Ensembl:ENSG00000030582 HGNC:4601 HPRD:00733 MIM:138945 Vega:OTTHUMG00000181816 GRN Bin Zhao, Yue Liu, Oliver He EPND FESD GluN2A LKS NMDAR2A NR2A WEB: http://www.ncbi.nlm.nih.gov/gene GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2903 RP11-297M9.2 16p13.2 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0001964 (EC: IEA); GO_0001975 (EC: IEA); GO_0004972 (EC: IBA); GO_0005234 (EC: IBA); GO_0005262 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11937501); GO_0005783 (EC: IEA); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 8768735); GO_0006810 (EC: TAS, PMID: 8768735); GO_0007215 (EC: TAS, PMID: 8768735); GO_0007268 (EC: TAS); GO_0007611 (EC: TAS, PMID: 7816096); GO_0007613 (EC: IEA); GO_0008021 (EC: IEA); GO_0008104 (EC: IEA); GO_0008270 (EC: ISS); GO_0008542 (EC: IEA); GO_0009611 (EC: IEA); GO_0009986 (EC: ISS); GO_0017146 (EC: IDA, PMID: 10480938); GO_0019233 (EC: IEA); GO_0022008 (EC: IEA); GO_0030054 (EC: IEA); GO_0030425 (EC: IBA); GO_0030431 (EC: IEA); GO_0033058 (EC: IEA); GO_0034220 (EC: IBA); GO_0035235 (EC: IBA); GO_0035249 (EC: IBA); GO_0042177 (EC: IEA); GO_0042417 (EC: IEA); GO_0042428 (EC: IEA); GO_0042493 (EC: IEA); GO_0042734 (EC: IEA); GO_0043065 (EC: IEA); GO_0045211 (EC: IBA); GO_0045471 (EC: IDA, PMID: 18445116); GO_0048167 (EC: IEA); GO_0051930 (EC: IEA); GO_0060079 (EC: IEA); GO_0097481 (EC: IEA) PMID: 1350383; 7524031; 7569905; 7695237; 7816096; 8061049; 8139656; 8163463; 8267632; 8563977; 8581564; 8601796; 8615909; 8665664; 8724036; 8768735; 8804048; 8821747; 8822372; 8845955; 8955056; 9231720; 9278515; 9286858; 9480759; 9481670; 9647694; 9651389; 9670010; 9745929; 9892651; 10195142; 10197777; 10336672; 10373510; 10448428; 10458595; 10479680; 10480938; 10555109; 10648730; 10748123; 10846184; 10862698; 10884433; 11104776; 11222640; 11279200; 11478920; 11483648; 11606043; 11675505; 11803122; 11854440; 11937501; 11985816; 12008020; 12068077; 12070168; 12082569; 12127670; 12147342; 12191494; 12391275; 12414113; 12419528; 12477932; 12531901; 12576483; 12697264; 12724619; 12775422; 12815021; 12890763; 12893641; 12923170; 12932824; 12933808; 12956718; 14622581; 14644469; 14699423; 14702039; 14732708; 14966475; 15254094; 15681389; 15742215; 15749123; 15774266; 15830322; 15888440; 16266783; 16476413; 16481105; 16489129; 16637659; 16697675; 16990796; 17011703; 17018562; 17081983; 17105731; 17255096; 17360663; 17433503; 17519952; 17569088; 17922030; 17942280; 17997397; 18029348; 18178157; 18445116; 18570704; 18606955; 18990687; 18991843; 19020013; 19036954; 19058789; 19086053; 19088076; 19156168; 19268276; 19352218; 19526283; 19834457; 19874574; 20041166; 20070378; 20094923; 20148871; 20379614; 20398908; 20448061; 20468064; 20677014; 20848605; 20890276; 21152063; 21371516; 21491143; 21499247; 21507155; 21670103; 21876681; 21883175; 21906983; 21948112; 22004137; 22114277; 22142193; 22486492; 22552781; 22833210; 22851457; 22940423; 23400010; 23453885; 23639431; 23693003; 23847085; 23933818; 23933819; 23933820; 23940648; 24227730 glutamate receptor, ionotropic, N-methyl D-aspartate 2A Ensembl:ENSG00000183454 HGNC:4585 HPRD:00698 MIM:138253 Vega:OTTHUMG00000129721 GRIN2A Bin Zhao, Yue Liu, Oliver He GluN2B MRD6 NMDAR2B NR2B hNR3 WEB: http://www.ncbi.nlm.nih.gov/gene GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2904 12p12 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0001662 (EC: IEA); GO_0001701 (EC: IEA); GO_0001964 (EC: IEA); GO_0001967 (EC: IEA); GO_0004972 (EC: IBA); GO_0005234 (EC: IBA); GO_0005262 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11937501); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 8768735); GO_0006810 (EC: TAS, PMID: 8768735); GO_0007215 (EC: TAS, PMID: 8768735); GO_0007268 (EC: TAS); GO_0007423 (EC: IEA); GO_0007611 (EC: TAS, PMID: 10485705); GO_0007612 (EC: IEA); GO_0007613 (EC: IEA); GO_0008021 (EC: IEA); GO_0008270 (EC: ISS); GO_0009986 (EC: ISS); GO_0014069 (EC: IEA); GO_0016594 (EC: IDA, PMID: 17047094); GO_0017146 (EC: IDA, PMID: 10480938); GO_0030054 (EC: IEA); GO_0030425 (EC: IBA); GO_0034220 (EC: IBA); GO_0035235 (EC: IBA); GO_0035249 (EC: IBA); GO_0043005 (EC: ISS); GO_0045211 (EC: IBA); GO_0045471 (EC: IDA, PMID: 18445116); GO_0048167 (EC: IEA); GO_0048266 (EC: IEA); GO_0050966 (EC: IEA); GO_0060079 (EC: IEA) PMID: 1350383; 7569905; 7695237; 7959773; 7999784; 8139656; 8163463; 8563977; 8581564; 8601796; 8615909; 8665664; 8724036; 8768735; 8780649; 8804048; 8821747; 8822372; 8845955; 8940188; 8955056; 9009191; 9231720; 9278515; 9326658; 9427503; 9481670; 9547169; 9581762; 9620694; 9647694; 9651389; 9670010; 9745929; 9806853; 10197777; 10341223; 10373510; 10381539; 10448428; 10458595; 10479680; 10480938; 10485705; 10488080; 10555109; 10620012; 10748157; 10846184; 10884433; 11024032; 11029657; 11278603; 11306676; 11317224; 11459059; 11483648; 11483655; 11588171; 11606043; 11679592; 11723117; 11799243; 11807413; 11844890; 11937501; 11956967; 11979061; 11997254; 12082569; 12127670; 12147342; 12191494; 12391275; 12414113; 12476325; 12477932; 12524444; 12531901; 12556902; 12650977; 12738960; 12753378; 12775422; 12815021; 12824739; 12857875; 12890763; 12893641; 14573320; 14622581; 14644469; 14662797; 15030493; 15083261; 15180478; 15211626; 15254094; 15489334; 15542698; 15673434; 15721239; 15742215; 15749123; 15812607; 15841096; 15866054; 16120608; 16266783; 16289038; 16380905; 16436603; 16481105; 16489129; 16549338; 16697675; 16766085; 16870468; 16911840; 16990796; 17010153; 17047094; 17224684; 17255096; 17360663; 17506933; 17506987; 17569088; 17620329; 17669510; 17942280; 17962190; 17997397; 18007143; 18068304; 18303265; 18445116; 18583979; 18606955; 18836292; 18976975; 18983893; 18991843; 19005876; 19011431; 19020013; 19036954; 19086053; 19088076; 19095845; 19156168; 19167335; 19192303; 19268276; 19279257; 19324536; 19328558; 19336002; 19350219; 19367581; 19453375; 19523047; 19526283; 19562769; 19591125; 19605943; 19726645; 19734545; 19784770; 19874574; 20175224; 20197096; 20201926; 20347576; 20379614; 20399867; 20421849; 20427279; 20438806; 20464528; 20468064; 20537720; 20537986; 20848605; 20859245; 20882066; 20890276; 20939817; 20945430; 20957330; 21116278; 21491143; 21597037; 21639937; 21670103; 21704719; 21749895; 21753020; 21782286; 21789901; 21827795; 21919190; 21948112; 22114277; 22116950; 22142193; 22326929; 22433450; 22479519; 22484476; 22552781; 22578441; 22610100; 22610502; 22711533; 22742935; 22832729; 22833210; 22833681; 22850629; 22936815; 22940423; 22986046; 23160955; 23201971; 23229837; 23377640; 23840674 glutamate receptor, ionotropic, N-methyl D-aspartate 2B HGNC:4586 HPRD:00697 MIM:138252 GRIN2B Bin Zhao, Yue Liu, Oliver He GCCR GCR GR GRL WEB: http://www.ncbi.nlm.nih.gov/gene NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2908 5q31.3 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0003700 (EC: IEA); GO_0004883 (EC: IEA); GO_0005496 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10364267); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005759 (EC: TAS, PMID: 10887960); GO_0005829 (EC: IEA); GO_0006111 (EC: IEA); GO_0006351 (EC: TAS, PMID: 10887960); GO_0006355 (EC: IDA, PMID: 19141540); GO_0006366 (EC: TAS, PMID: 8621628); GO_0006367 (EC: TAS); GO_0007165 (EC: TAS, PMID: 7769088); GO_0008211 (EC: IEA); GO_0008270 (EC: IEA); GO_0010467 (EC: TAS); GO_0016020 (EC: IEA); GO_0016568 (EC: IEA); GO_0030325 (EC: IEA); GO_0031946 (EC: IEA); GO_0043525 (EC: IEA); GO_0043565 (EC: IEA); GO_0046983 (EC: IEA); GO_0060603 (EC: IEA) PMID: 1152650; 1469072; 1562545; 1612132; 1704018; 1707881; 1865905; 1958537; 2019585; 2026589; 2793174; 2867473; 3597702; 3841189; 6261922; 6266631; 6509026; 6621034; 7254211; 7264103; 7295795; 7491111; 7621901; 7659084; 7683692; 7724608; 7769088; 7796394; 7823959; 7873448; 7877627; 7887964; 8051160; 8089152; 8107808; 8125298; 8157642; 8223438; 8269959; 8288028; 8290595; 8316249; 8341706; 8349631; 8358712; 8358735; 8445027; 8449898; 8530516; 8621522; 8621628; 8645634; 8733011; 8800208; 8863343; 8878484; 8898375; 9038175; 9079630; 9089287; 9115274; 9128241; 9148915; 9150737; 9154805; 9162033; 9195923; 9199329; 9215863; 9261129; 9334248; 9334723; 9348235; 9353307; 9388192; 9426156; 9435432; 9482670; 9528750; 9584182; 9590696; 9603979; 9637764; 9649342; 9671457; 9703718; 9742105; 9817600; 9873044; 9874563; 9915858; 9920895; 9928932; 10066374; 10085091; 10187825; 10359081; 10364267; 10391209; 10430878; 10477749; 10480874; 10490647; 10508170; 10517667; 10518526; 10566686; 10567404; 10601862; 10639135; 10659697; 10688647; 10691735; 10713165; 10713182; 10731636; 10784585; 10848625; 10866662; 10887960; 10898924; 10902803; 10903152; 10903900; 10933727; 10958685; 10995388; 11005817; 11027313; 11080152; 11096094; 11101523; 11117529; 11119758; 11146632; 11152650; 11154266; 11158330; 11162542; 11229437; 11238589; 11250851; 11266503; 11279115; 11287026; 11344238; 11358809; 11358960; 11435610; 11463861; 11555652; 11562347; 11571596; 11589680; 11591700; 11673782; 11689055; 11701741; 11704662; 11708406; 11710540; 11711524; 11739747; 11751894; 11792840; 11812797; 11818365; 11873873; 11932321; 11971959; 11983486; 11996936; 12000743; 12011091; 12039077; 12039962; 12050230; 12093808; 12099703; 12114257; 12114309; 12118039; 12144530; 12145329; 12151000; 12193561; 12208951; 12225995; 12237016; 12237292; 12351458; 12351702; 12361945; 12379213; 12430185; 12444143; 12466272; 12477485; 12477932; 12487626; 12490527; 12552091; 12569182; 12581885; 12595526; 12612067; 12623935; 12634356; 12637494; 12642036; 12686538; 12711001; 12730237; 12738786; 12748280; 12754700; 12773562; 12773573; 12787894; 12805402; 12807506; 12810720; 12843156; 12864802; 12874288; 12902338; 12903052; 12917342; 12920235; 12933681; 12974633; 14521715; 14522952; 14616881; 14617768; 14634838; 14715855; 14733805; 14739255; 14749509; 14764763; 14764810; 14966297; 15016838; 15044598; 15062560; 15142377; 15159550; 15171715; 15212141; 15265776; 15265780; 15276593; 15289446; 15292341; 15372022; 15380361; 15459252; 15462611; 15489334; 15497438; 15501915; 15511603; 15521959; 15531761; 15545613; 15550679; 15557560; 15576061; 15576464; 15590693; 15591061; 15604093; 15611350; 15638722; 15657031; 15698551; 15713213; 15725353; 15746190; 15755863; 15761032; 15769988; 15770078; 15774500; 15784617; 15797250; 15826950; 15832179; 15862824; 15866175; 15870285; 15879558; 15895983; 15916966; 15919839; 15933212; 15941832; 15955845; 15956716; 16083972; 16087666; 16131566; 16134770; 16143103; 16150697; 16189295; 16192984; 16204701; 16216909; 16222046; 16236267; 16239257; 16263717; 16319314; 16362036; 16380507; 16387802; 16423881; 16429131; 16446173; 16450310; 16458268; 16469772; 16523501; 16580345; 16610949; 16610957; 16615046; 16619302; 16621324; 16624805; 16636127; 16638864; 16648810; 16676134; 16684836; 16725041; 16728546; 16740143; 16759008; 16762839; 16806572; 16806906; 16809634; 16849409; 16855182; 16888650; 16890204; 16895953; 16914312; 16971495; 16973758; 16980656; 17003263; 17043312; 17065567; 17070695; 17081986; 17116691; 17133261; 17167179; 17184882; 17185395; 17186943; 17236775; 17239375; 17242171; 17242172; 17291258; 17382897; 17387179; 17392827; 17395275; 17404046; 17407502; 17438138; 17442162; 17455211; 17460547; 17490654; 17496926; 17512111; 17517920; 17522428; 17532759; 17535992; 17540466; 17552871; 17556642; 17559307; 17563720; 17572486; 17592773; 17602195; 17633252; 17633260; 17635946; 17641689; 17681029; 17682054; 17703412; 17704997; 17716631; 17848410; 17853270; 17884810; 17937535; 17951535; 17952860; 17989362; 18028994; 18029348; 18047640; 18079322; 18086889; 18096310; 18156379; 18160712; 18165172; 18182467; 18194492; 18195193; 18219286; 18246526; 18248637; 18269582; 18286599; 18295813; 18331827; 18337589; 18343955; 18362306; 18385010; 18396779; 18398271; 18407829; 18408151; 18417736; 18468809; 18483179; 18502562; 18510611; 18511904; 18515658; 18536531; 18562626; 18583474; 18595687; 18636124; 18660489; 18663733; 18668364; 18728163; 18772142; 18789525; 18801933; 18812484; 18818748; 18822299; 18827003; 18830906; 18838498; 18838540; 18854398; 18945813; 18952539; 18958157; 18983327; 18996102; 19005987; 19007848; 19007849; 19008334; 19019335; 19051288; 19074285; 19086053; 19089807; 19095219; 19100874; 19133972; 19141540; 19146914; 19174530; 19177170; 19183974; 19188741; 19207316; 19222494; 19230884; 19234455; 19234457; 19241242; 19248771; 19258923; 19275580; 19275583; 19275585; 19282465; 19318444; 19322201; 19336230; 19336370; 19339282; 19365399; 19372434; 19373457; 19375647; 19413563; 19429432; 19435830; 19450127; 19450611; 19453261; 19458171; 19463884; 19466222; 19471022; 19484926; 19491387; 19527514; 19545546; 19548263; 19562035; 19564704; 19570036; 19578796; 19586900; 19595997; 19605973; 19621425; 19628874; 19633971; 19646928; 19673019; 19683543; 19691529; 19692572; 19723618; 19758697; 19778524; 19779205; 19782477; 19783104; 19797430; 19801529; 19805480; 19818358; 19841061; 19874574; 19875381; 19875955; 19913032; 19913121; 19940520; 19948975; 20012529; 20015838; 20015871; 20018896; 20032106; 20035271; 20036846; 20093418; 20124551; 20137628; 20140262; 20156337; 20156759; 20170710; 20195357; 20199670; 20211142; 20219685; 20308989; 20335448; 20347598; 20351714; 20371666; 20376328; 20398657; 20399565; 20403506; 20419394; 20438742; 20440229; 20446002; 20448266; 20450542; 20472303; 20484466; 20485444; 20488636; 20503287; 20543003; 20545708; 20547006; 20561560; 20584071; 20602615; 20619282; 20628086; 20634891; 20660302; 20661446; 20680430; 20697295; 20712049; 20716560; 20727199; 20731635; 20733583; 20734064; 20841450; 20843780; 20850457; 20855522; 20861124; 20885351; 21050724; 21078539; 21084380; 21093928; 21113676; 21127044; 21146942; 21147850; 21148795; 21164266; 21169818; 21190962; 21234764; 21354648; 21355091; 21419342; 21438141; 21438768; 21473041; 21474440; 21477816; 21489275; 21511880; 21521257; 21521940; 21527497; 21531081; 21633323; 21641918; 21646426; 21664385; 21693764; 21730049; 21742609; 21750107; 21760925; 21764460; 21788965; 21789663; 21803757; 21853119; 21868756; 21881570; 21883217; 21900206; 21912096; 21930780; 21945289; 21963094; 21971518; 21980503; 21984896; 21988832; 21995950; 22003412; 22008062; 22015776; 22018181; 22032841; 22048965; 22068557; 22083731; 22085474; 22088926; 22174376; 22177699; 22185489; 22205602; 22227972; 22295073; 22357529; 22366879; 22371499; 22425674; 22427805; 22441538; 22444201; 22457708; 22469783; 22487832; 22507373; 22516378; 22516993; 22533504; 22570980; 22576823; 22587663; 22587831; 22592921; 22698871; 22728713; 22771494; 22773829; 22781842; 22798432; 22801563; 22810058; 22812453; 22832351; 22846929; 22848740; 22851186; 22855579; 22863883; 22879541; 22922069; 23028665; 23033538; 23033539; 23046934; 23055001; 23055525; 23068076; 23072594; 23073785; 23123359; 23124618; 23125313; 23127816; 23132854; 23148886; 23151527; 23176645; 23178279; 23196783; 23204024; 23209664; 23212335; 23219223; 23222642; 23228967; 23239753; 23239757; 23290588; 23297131; 23307810; 23325854; 23329746; 23334186; 23355259; 23391271; 23392094; 23393177; 23426617; 23428870; 23435844; 23440419; 23449091; 23493285; 23506845; 23548248; 23566423; 23603102; 23778418; 23814048; 23820903; 23892712; 24097989; 24128430; 24186266; 24316275 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Ensembl:ENSG00000113580 HGNC:7978 HPRD:00679 MIM:138040 Vega:OTTHUMG00000129677 NR3C1 Bin Zhao, Yue Liu, Oliver He FSP GRO1 GROa MGSA MGSA-a NAP-3 SCYB1 WEB: http://www.ncbi.nlm.nih.gov/gene CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2919 4q21 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0005102 (EC: TAS, PMID: 10820279); GO_0005576 (EC: TAS); GO_0005615 (EC: IEA); GO_0006935 (EC: TAS, PMID: 10820279); GO_0006954 (EC: IEA); GO_0006955 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10820279); GO_0007186 (EC: TAS, PMID: 10820279); GO_0007399 (EC: TAS, PMID: 9058825); GO_0008009 (EC: IEA); GO_0008047 (EC: TAS, PMID: 9079638); GO_0008083 (EC: IEA); GO_0008283 (EC: TAS, PMID: 8380167); GO_0008285 (EC: TAS, PMID: 9551928); GO_0030036 (EC: TAS, PMID: 9725262); GO_0035556 (EC: TAS, PMID: 9551928); GO_0043085 (EC: TAS, PMID: 9079638); GO_0060326 (EC: TAS, PMID: 10820279) PMID: 1379593; 1906501; 2129556; 2182761; 2217207; 2655583; 2670560; 2890161; 2909392; 2970963; 3264403; 7561066; 7592830; 7806518; 8089846; 8380167; 8397104; 8550564; 8597869; 8702798; 8940121; 8942852; 9058825; 9079638; 9152234; 9551928; 9725262; 10095777; 10343098; 10437780; 10820279; 10881932; 11023497; 11349045; 11390582; 11470861; 11524231; 11816717; 12012624; 12089333; 12388718; 12477932; 12591113; 12734381; 12744776; 13679391; 14530367; 15133028; 15218300; 15340161; 15489334; 15492419; 15843053; 15896780; 15994316; 16086366; 16098041; 16567391; 16617094; 16712791; 16934308; 16941962; 17022986; 17060621; 17062666; 17096385; 17456471; 17466952; 17581194; 17703315; 17703412; 17999991; 18056965; 18065201; 18211687; 18240029; 18276907; 18283335; 18451219; 18577758; 19103522; 19176759; 19258312; 19258923; 19430878; 19435811; 19549892; 19780053; 19838218; 19906815; 20042592; 20195728; 20237496; 20495539; 20503287; 20621720; 20628624; 20685145; 20702723; 20731665; 21042742; 21075844; 21220697; 21257927; 21343381; 21396766; 21531038; 21820916; 21928244; 21994122; 22030312; 22069268; 22125641; 22129625; 22173151; 22183310; 22251138; 22615136; 22732298; 22770218; 22902060; 22975476; 23027620; 23043537; 23128233; 23198952; 23207068; 23225384; 23269549; 23334998; 23389772; 23444042; 23479735; 23505918; 23519936; 23554905; 23732813; 23815949; 23967336; 24273934; 24600982 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Ensembl:ENSG00000163739 HGNC:4602 HPRD:01119 MIM:155730 Vega:OTTHUMG00000160866 CXCL1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene GSK3A glycogen synthase kinase 3 alpha 2931 19q13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0003073 (EC: ISS); GO_0003214 (EC: ISS); GO_0004674 (EC: IDA, PMID: 11035810); GO_0005515 (EC: IPI, PMID: 16365045); GO_0005524 (EC: IEA); GO_0005829 (EC: TAS, PMID: 11035810); GO_0005977 (EC: IEA); GO_0006468 (EC: IDA, PMID: 11035810); GO_0006987 (EC: TAS); GO_0007173 (EC: TAS); GO_0007399 (EC: IEA); GO_0008286 (EC: ISS, PMID: 18285345); GO_0008543 (EC: TAS); GO_0010905 (EC: IC, PMID: 11035810); GO_0016055 (EC: IEA); GO_0030819 (EC: ISS); GO_0030877 (EC: NAS, PMID: 19759537); GO_0030877 (EC: TAS, PMID: 19366350); GO_0030968 (EC: TAS); GO_0032007 (EC: ISS); GO_0032869 (EC: IMP, PMID: 17569761); GO_0034236 (EC: IPI, PMID: 11035810); GO_0036016 (EC: ISS); GO_0038095 (EC: TAS); GO_0043161 (EC: ISS); GO_0044267 (EC: TAS); GO_0045087 (EC: TAS); GO_0045719 (EC: TAS, PMID: 19366350); GO_0045732 (EC: NAS, PMID: 19759537); GO_0045823 (EC: ISS); GO_0046325 (EC: IMP, PMID: 17569761); GO_0046627 (EC: IMP, PMID: 17569761); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0050321 (EC: TAS, PMID: 19366350); GO_0051348 (EC: IMP, PMID: 17569761); GO_0061052 (EC: ISS); GO_0071879 (EC: ISS); GO_0090090 (EC: TAS, PMID: 19366350); GO_0097192 (EC: ISS); GO_1901030 (EC: ISS); GO_2000077 (EC: TAS, PMID: 19366350); GO_2000466 (EC: TAS, PMID: 19366350); GO_2000467 (EC: ISS) PMID: 7706316; 7715701; 7931292; 8404858; 8524413; 8725894; 9468292; 9735171; 9809441; 10448973; 11035810; 11481324; 11500362; 11509608; 11749387; 11884598; 12054501; 12086949; 12379450; 12477932; 12665592; 12675919; 12761548; 12890758; 14550568; 14563837; 14635195; 14645548; 15057824; 15194499; 15302935; 15324660; 15361837; 15469820; 15489334; 15592455; 15631989; 15678105; 16365045; 16371461; 16446437; 16537926; 16543145; 16543730; 16611631; 16757548; 16806170; 16912034; 16934436; 16984735; 16987514; 17052453; 17139249; 17158447; 17192257; 17325032; 17505062; 17569761; 17609434; 18042454; 18285345; 18450971; 18500637; 18516299; 18826950; 18829575; 18955053; 19131971; 19136008; 19142874; 19156168; 19323791; 19336475; 19366350; 19464003; 19507191; 19656851; 19705135; 19706605; 19759537; 19995607; 20080974; 20113358; 20368287; 20371704; 20541704; 20668436; 20831597; 20920357; 21139048; 21220517; 21255011; 21320285; 21436692; 21576335; 21718540; 21775285; 21890473; 21896753; 22022450; 22065737; 22326953; 22328534; 22384031; 22505724; 22539113; 22539723; 22658458; 22939624; 23000965; 23192081; 23243017; 23352529; 23369789; 23602568; 23621307; 23798682; 23959799 glycogen synthase kinase 3 alpha GSK3A Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene GSK3B glycogen synthase kinase 3 beta 2932 3q13.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000320 (EC: IEA); GO_0001085 (EC: IPI); GO_0001837 (EC: IMP, PMID: 15448698); GO_0001954 (EC: IMP, PMID: 18156211); GO_0002039 (EC: IDA, PMID: 14744935); GO_0004674 (EC: IDA, PMID: 11035810); GO_0004674 (EC: ISS); GO_0005178 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11004522); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005737 (EC: IDA, PMID: 14744935); GO_0005813 (EC: IDA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA); GO_0005977 (EC: IDA, PMID: 8638126); GO_0006349 (EC: IEA); GO_0006468 (EC: IDA, PMID: 11035810); GO_0006611 (EC: IEA); GO_0006983 (EC: IDA, PMID: 14744935); GO_0007173 (EC: TAS); GO_0007411 (EC: TAS); GO_0007520 (EC: IEA); GO_0007623 (EC: ISS); GO_0008013 (EC: IPI, PMID: 8638126); GO_0008543 (EC: TAS); GO_0009887 (EC: IEA); GO_0010226 (EC: IEA); GO_0010614 (EC: IEA); GO_0010800 (EC: IEA); GO_0016301 (EC: IDA, PMID: 15448698); GO_0016301 (EC: TAS); GO_0016477 (EC: IEA); GO_0018105 (EC: IDA, PMID: 11104755); GO_0019901 (EC: IPI, PMID: 18348280); GO_0021766 (EC: IMP, PMID: 19581563); GO_0030010 (EC: IEA); GO_0030426 (EC: IEA); GO_0030529 (EC: IEA); GO_0030877 (EC: IDA, PMID: 16188939); GO_0030877 (EC: TAS, PMID: 19366350); GO_0031333 (EC: IMP, PMID: 16188939); GO_0031334 (EC: IDA, PMID: 8638126); GO_0031625 (EC: IPI); GO_0032091 (EC: IDA, PMID: 16890161); GO_0032092 (EC: ISS); GO_0032855 (EC: IMP, PMID: 18156211); GO_0032886 (EC: IMP); GO_0033138 (EC: IEA); GO_0034236 (EC: IPI, PMID: 11035810); GO_0035255 (EC: IEA); GO_0035372 (EC: IEA); GO_0035556 (EC: IDA, PMID: 14749367); GO_0036016 (EC: ISS); GO_0038095 (EC: TAS); GO_0042493 (EC: IEA); GO_0043025 (EC: IEA); GO_0043066 (EC: IDA, PMID: 14744935); GO_0043197 (EC: IEA); GO_0043198 (EC: IEA); GO_0043407 (EC: IEA); GO_0044027 (EC: IEA); GO_0044337 (EC: IEA); GO_0045087 (EC: TAS); GO_0045121 (EC: IEA); GO_0045444 (EC: IEA); GO_0045719 (EC: TAS, PMID: 19366350); GO_0045732 (EC: IC, PMID: 16188939); GO_0045944 (EC: IEA); GO_0046827 (EC: IDA, PMID: 14744935); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0048156 (EC: IEA); GO_0048168 (EC: IEA); GO_0048471 (EC: IEA); GO_0050321 (EC: IDA, PMID: 14690523); GO_0050774 (EC: IEA); GO_0051059 (EC: IPI, PMID: 15465828); GO_0051534 (EC: IMP, PMID: 9072970); GO_0060070 (EC: IC, PMID: 9601641); GO_0060070 (EC: IDA, PMID: 18787224); GO_0071109 (EC: IMP, PMID: 19581563); GO_0071260 (EC: IEA); GO_0090090 (EC: TAS, PMID: 19366350); GO_0097192 (EC: ISS); GO_1901030 (EC: ISS); GO_2000077 (EC: TAS, PMID: 19366350); GO_2000466 (EC: TAS, PMID: 19366350); GO_2000738 (EC: IEA) PMID: 1181841; 1324914; 1330687; 1333807; 6772446; 7514173; 7566346; 7642555; 7706316; 7980435; 8247524; 8382613; 8404858; 8524413; 8638126; 8764598; 8861947; 8889548; 8999860; 9072970; 9199504; 9271238; 9353289; 9468292; 9482734; 9546672; 9565682; 9566905; 9570753; 9601641; 9731200; 9734785; 9735171; 9736715; 9771888; 9809441; 9819408; 9832145; 9832503; 10074433; 10090741; 10228155; 10330181; 10330403; 10347142; 10428053; 10428961; 10486203; 10488109; 10523816; 10567568; 10581160; 10587587; 10653665; 10671552; 10753899; 10826493; 10910956; 10936190; 10966653; 11004522; 11035810; 11104755; 11152665; 11166179; 11181841; 11251183; 11311121; 11320080; 11425860; 11427888; 11440715; 11481324; 11483158; 11495916; 11500362; 11524435; 11738041; 11781156; 11809746; 11812770; 11818547; 11835406; 11877389; 11903055; 11955436; 11967263; 11980723; 11986994; 12000790; 12048243; 12051714; 12054501; 12063245; 12064478; 12086949; 12095675; 12114015; 12123574; 12130654; 12133000; 12147701; 12162494; 12167628; 12182887; 12183362; 12226093; 12228224; 12244165; 12364325; 12376533; 12379450; 12387894; 12387897; 12417018; 12434148; 12477932; 12511557; 12527198; 12554650; 12566926; 12584189; 12603528; 12663502; 12761178; 12778079; 12794074; 12796505; 12808104; 12819195; 12820959; 12829841; 12871932; 12885254; 12900420; 12927815; 12969793; 14518171; 14520463; 14523002; 14536078; 14550568; 14561750; 14563837; 14612456; 14617795; 14635195; 14636947; 14645548; 14660640; 14690523; 14691449; 14729058; 14729229; 14744935; 14749367; 14985354; 14988008; 14988390; 14991743; 15020233; 15026145; 15073173; 15132987; 15147888; 15178331; 15178691; 15179015; 15231747; 15252116; 15254796; 15302935; 15327769; 15345747; 15351432; 15361837; 15375789; 15379854; 15383283; 15448698; 15456937; 15465828; 15469820; 15470047; 15489334; 15517997; 15522877; 15555766; 15592455; 15609321; 15631989; 15647282; 15652488; 15678105; 15688030; 15719395; 15752768; 15799972; 15824731; 15829978; 15940626; 15942663; 15951569; 15963640; 15981102; 15993040; 16007092; 16009706; 16027724; 16039586; 16043125; 16055726; 16076840; 16107342; 16115820; 16123141; 16141410; 16174773; 16188939; 16198352; 16199882; 16210249; 16247449; 16257959; 16278684; 16282323; 16289845; 16315267; 16341242; 16344560; 16365045; 16371352; 16397405; 16420965; 16421604; 16428445; 16428884; 16462886; 16519508; 16528748; 16537926; 16543145; 16543730; 16551619; 16571670; 16601113; 16611631; 16645641; 16705181; 16753179; 16757548; 16767496; 16787706; 16788573; 16814287; 16861141; 16882987; 16890161; 16893889; 16912034; 16916907; 16934436; 16936772; 16942622; 16951223; 16959574; 16964243; 16981698; 16982692; 16984735; 16987250; 16987514; 17016438; 17028556; 17046823; 17050006; 17052453; 17072303; 17078951; 17081983; 17098228; 17107957; 17139249; 17150190; 17159916; 17160944; 17192257; 17233643; 17241872; 17270183; 17273789; 17283049; 17318175; 17325032; 17353931; 17357145; 17360711; 17368486; 17387146; 17389597; 17434145; 17437043; 17437044; 17438332; 17475833; 17483602; 17486076; 17512525; 17522055; 17562708; 17565981; 17590240; 17609434; 17621172; 17621269; 17628506; 17671694; 17681942; 17697341; 17711861; 17717075; 17908237; 17912008; 17951252; 17972518; 17976739; 17990294; 17991736; 17991738; 18029348; 18045539; 18055457; 18083346; 18156211; 18167338; 18172167; 18178198; 18195729; 18198341; 18201972; 18218855; 18219478; 18221734; 18223684; 18243662; 18252708; 18263590; 18316369; 18316598; 18348280; 18367454; 18391981; 18391982; 18408738; 18437054; 18450971; 18451303; 18500637; 18552505; 18588978; 18593713; 18602000; 18606491; 18615589; 18628988; 18632640; 18632848; 18660489; 18676680; 18687691; 18689794; 18708403; 18768676; 18769147; 18782353; 18786229; 18787224; 18801732; 18804163; 18806775; 18826950; 18829575; 18838540; 18852124; 18852354; 18855532; 18952601; 18955029; 18955053; 18973553; 18991351; 18996102; 18996844; 19003984; 19007860; 19022564; 19038973; 19050253; 19060929; 19061640; 19104043; 19107203; 19116273; 19126544; 19131971; 19142874; 19148484; 19154537; 19156168; 19170196; 19180470; 19188159; 19190323; 19202075; 19237556; 19249679; 19265551; 19274078; 19289791; 19303846; 19321622; 19322201; 19323791; 19366350; 19401395; 19411070; 19429119; 19429245; 19453261; 19454488; 19457211; 19470470; 19472218; 19477245; 19481076; 19501118; 19505532; 19528467; 19557001; 19573950; 19576224; 19581563; 19584164; 19607922; 19625176; 19639192; 19656851; 19657367; 19659461; 19681904; 19682504; 19688630; 19692168; 19698783; 19706605; 19711366; 19713527; 19717166; 19727391; 19751508; 19754670; 19757160; 19797085; 19823589; 19833727; 19841191; 19874574; 19882709; 19903789; 19913121; 19995607; 20007971; 20008284; 20015462; 20031160; 20033742; 20039940; 20080974; 20103767; 20106550; 20110283; 20113358; 20127713; 20128690; 20154711; 20159967; 20160451; 20167573; 20178594; 20190034; 20204404; 20219685; 20226637; 20308328; 20333643; 20351102; 20352103; 20357815; 20368287; 20371704; 20388706; 20399743; 20448354; 20453000; 20454507; 20457218; 20468064; 20484041; 20497256; 20508983; 20510151; 20513428; 20525681; 20531236; 20541704; 20561405; 20562859; 20599907; 20602615; 20605420; 20615469; 20618448; 20628086; 20644561; 20647544; 20648061; 20649541; 20679343; 20682308; 20682768; 20709358; 20800594; 20818790; 20831597; 20848477; 20849862; 20856200; 20864106; 20889919; 20920357; 20934407; 20962236; 21038412; 21061060; 21105670; 21110852; 21115199; 21118991; 21130530; 21139048; 21145761; 21159074; 21160051; 21179545; 21189258; 21204008; 21212533; 21217772; 21228102; 21238544; 21242974; 21254166; 21278490; 21303975; 21310903; 21314327; 21317289; 21328461; 21334395; 21343617; 21422248; 21435461; 21436692; 21441955; 21443865; 21460223; 21471285; 21502811; 21514616; 21527318; 21549170; 21571466; 21609933; 21613824; 21632881; 21661417; 21671254; 21700708; 21725365; 21737790; 21757741; 21790007; 21795403; 21821001; 21832049; 21873331; 21887250; 21890473; 21898401; 21900206; 21910689; 21965288; 21985244; 21988832; 21996267; 22022450; 22039048; 22039301; 22048123; 22087308; 22093618; 22102280; 22140263; 22142472; 22144179; 22179823; 22184106; 22193544; 22201186; 22214783; 22234583; 22243669; 22246236; 22262180; 22262776; 22270359; 22286758; 22349353; 22363707; 22384031; 22413565; 22419096; 22419736; 22455883; 22460328; 22505724; 22509369; 22513362; 22514281; 22534782; 22539113; 22539723; 22577147; 22586270; 22613765; 22658982; 22661511; 22679108; 22682247; 22687243; 22690042; 22692215; 22707636; 22710716; 22732552; 22751928; 22771494; 22773696; 22775567; 22785398; 22810307; 22814751; 22815195; 22824801; 22825252; 22832527; 22832604; 22834106; 22855295; 22863953; 22893788; 22898789; 22910909; 22933777; 22936801; 22939629; 22960426; 22965877; 22970250; 22976805; 22990942; 22999923; 23000965; 23002080; 23010592; 23011797; 23021822; 23023215; 23030648; 23077590; 23085750; 23104438; 23110823; 23160194; 23164673; 23166798; 23184735; 23185275; 23185298; 23192081; 23202730; 23211630; 23243017; 23277198; 23279147; 23288365; 23314850; 23328640; 23349801; 23352529; 23369789; 23379509; 23389291; 23389968; 23402899; 23408424; 23408967; 23413973; 23432902; 23442801; 23455922; 23463670; 23505128; 23507969; 23525328; 23551536; 23559006; 23582741; 23583197; 23598903; 23602568; 23614534; 23615537; 23621307; 23623971; 23628795; 23669633; 23673211; 23729362; 23761130; 23798682; 23818587; 23820376; 23824745; 23824844; 23845472; 23846217; 23851680; 23853095; 23874688; 23880761; 23900020; 23911749; 23959174; 23959799; 23983127; 24001613; 24027432; 24134204; 24142875; 24163370; 24333432; 24427901 glycogen synthase kinase 3 beta GSK3B Bin Zhao, Yue Liu, Oliver He HEL-75 WEB: http://www.ncbi.nlm.nih.gov/gene GSR glutathione reductase 2936 8p21.1 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0004362 (EC: TAS); GO_0005759 (EC: TAS); GO_0005829 (EC: TAS); GO_0006749 (EC: IEA); GO_0009055 (EC: TAS, PMID: 947404); GO_0015949 (EC: TAS); GO_0044281 (EC: TAS); GO_0045454 (EC: IEA); GO_0050660 (EC: IEA); GO_0050661 (EC: IEA); GO_0055086 (EC: TAS); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 302667; 923580; 947404; 2185014; 2306116; 2379581; 3656429; 6822532; 7060551; 7334521; 7663973; 8626496; 8889548; 9151953; 9174360; 9546215; 10708558; 11204445; 11273669; 11710935; 12095224; 12447480; 12477932; 12516882; 12533953; 12630007; 12826156; 12838767; 12838770; 12901426; 14637279; 15149466; 15489334; 15592455; 15978628; 16009940; 16169070; 16236267; 16341674; 16421571; 16424062; 16868544; 17185460; 17206382; 17601350; 18341267; 18638483; 18977241; 19056867; 19124506; 19322201; 19377255; 19527700; 19560448; 19806191; 19896490; 19913121; 20200426; 20379614; 20485444; 20586645; 20628086; 20628807; 20877624; 21139048; 21417634; 21890473; 21906983; 21988832; 22089180; 22863883; 22939629; 22944692; 23000965; 23637325; 23770363; 24250222 glutathione reductase Ensembl:ENSG00000104687 HGNC:4623 HPRD:00704 MIM:138300 Vega:OTTHUMG00000163946 GSR Bin Zhao, Yue Liu, Oliver He GSY GYS WEB: http://www.ncbi.nlm.nih.gov/gene GYS1 glycogen synthase 1 (muscle) 2997 19q13.3 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0004373 (EC: EXP); GO_0004373 (EC: IDA, PMID: 16275910); GO_0005515 (EC: IPI, PMID: 16189514); GO_0005536 (EC: IEA); GO_0005829 (EC: TAS); GO_0005975 (EC: TAS); GO_0005978 (EC: IDA, PMID: 16275910); GO_0005978 (EC: IEA); GO_0005978 (EC: TAS); GO_0006006 (EC: TAS); GO_0007507 (EC: IEA); GO_0016234 (EC: IEA); GO_0019901 (EC: IPI, PMID: 16275910); GO_0044281 (EC: TAS); GO_0061547 (EC: EXP) PMID: 2117608; 2493642; 6772446; 7631777; 7657035; 8062946; 8125298; 8280084; 8449521; 9010351; 9346895; 9628874; 10924520; 11092303; 11147787; 11251056; 11427888; 12411100; 12477932; 12732844; 12870167; 15194499; 15282316; 15342556; 15489334; 15855312; 15955076; 16115820; 16189514; 16275910; 16282323; 17055998; 17137217; 17353931; 17356695; 17928598; 18544618; 18996102; 19339242; 19420105; 19578796; 19615732; 19773279; 19837931; 19913121; 20017397; 20300197; 20384434; 20562859; 20602615; 20628086; 21139048; 21145461; 21832049; 21890473; 21906983; 21963094; 21985244; 21987572; 22403297; 22505724; 22952844; 23000965; 23134486; 23321478; 24049095 glycogen synthase 1 (muscle) Ensembl:ENSG00000104812 HGNC:4706 HPRD:00721 MIM:138570 Vega:OTTHUMG00000150723 GYS1 Bin Zhao, Yue Liu, Oliver He 17b-HSD10 ABAD CAMR DUPXp11.22 ERAB HADH2 HCD2 MHBD MRPP2 MRX17 MRX31 MRXS10 SCHAD SDR5C1 WEB: http://www.ncbi.nlm.nih.gov/gene HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 3028 RP3-339A18.2 Xp11.2 20140408 9606 X protein-coding Official from a nomenclature committee GO_0003857 (EC: EXP); GO_0005515 (EC: IPI, PMID: 18984158); GO_0005737 (EC: TAS, PMID: 9338779); GO_0005739 (EC: ISS); GO_0005743 (EC: IEA); GO_0005759 (EC: TAS); GO_0005783 (EC: IEA); GO_0005886 (EC: TAS, PMID: 9338779); GO_0006629 (EC: TAS, PMID: 9338779); GO_0008033 (EC: IEA); GO_0008709 (EC: TAS, PMID: 9338779); GO_0009083 (EC: TAS); GO_0030283 (EC: IEA); GO_0034641 (EC: TAS); GO_0044281 (EC: TAS); GO_0044822 (EC: IDA); GO_0047015 (EC: IEA) PMID: 8687463; 9061028; 9338779; 9553139; 9671743; 9712734; 9851691; 9890977; 10329704; 10371197; 10600649; 11403151; 11430884; 11559359; 11869808; 12477932; 12696021; 12917011; 14672739; 15087549; 15342248; 15489334; 15665036; 15804423; 16021519; 16148061; 16176262; 16344560; 16899120; 17236142; 17266347; 17500595; 17618155; 17707551; 17917077; 18252223; 18692800; 18765932; 18984158; 19027726; 19343046; 19422801; 19449377; 19601895; 19706438; 19735314; 19738201; 19756307; 20000738; 20059664; 20077426; 20186120; 20638476; 20664630; 21081666; 21139048; 21145461; 21382475; 21890473; 21900206; 21906983; 21907836; 22127393; 22174920; 22217844; 22623428; 22863883; 22939629; 23000965; 23266819; 23667531; 23755257; 23834306 hydroxysteroid (17-beta) dehydrogenase 10 Ensembl:ENSG00000072506 HGNC:4800 HPRD:02223 MIM:300256 Vega:OTTHUMG00000021612 HSD17B10 Bin Zhao, Yue Liu, Oliver He HD IT15 WEB: http://www.ncbi.nlm.nih.gov/gene HTT huntingtin 3064 4p16.3 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0000050 (EC: IEA); GO_0000052 (EC: IEA); GO_0000132 (EC: IMP); GO_0002039 (EC: IPI, PMID: 10823891); GO_0005515 (EC: IPI, PMID: 10823891); GO_0005634 (EC: IDA, PMID: 12783847); GO_0005737 (EC: IDA, PMID: 15064418); GO_0005739 (EC: IEA); GO_0005770 (EC: IDA, PMID: 17704510); GO_0005776 (EC: IDA, PMID: 17704510); GO_0005783 (EC: IDA, PMID: 17704510); GO_0005794 (EC: IDA, PMID: 15837803); GO_0005829 (EC: IDA); GO_0006606 (EC: IEA); GO_0006888 (EC: IEA); GO_0006890 (EC: IMP); GO_0007029 (EC: IEA); GO_0007030 (EC: IMP); GO_0007212 (EC: IEA); GO_0007283 (EC: IEA); GO_0007569 (EC: IEA); GO_0007625 (EC: IEA); GO_0007626 (EC: IEA); GO_0008088 (EC: IEA); GO_0008134 (EC: IBA); GO_0008340 (EC: IEA); GO_0008542 (EC: IEA); GO_0009952 (EC: IEA); GO_0016197 (EC: IEA); GO_0016234 (EC: IEA); GO_0019244 (EC: IEA); GO_0019805 (EC: IEA); GO_0021756 (EC: IEA); GO_0021988 (EC: IEA); GO_0021990 (EC: IEA); GO_0030073 (EC: IEA); GO_0030424 (EC: IDA, PMID: 7748555); GO_0030425 (EC: IDA, PMID: 7748555); GO_0030659 (EC: IDA, PMID: 7748555); GO_0034047 (EC: IMP); GO_0034452 (EC: IPI, PMID: 18922795); GO_0035176 (EC: IEA); GO_0042445 (EC: IEA); GO_0042802 (EC: IPI); GO_0043234 (EC: IDA, PMID: 18922795); GO_0043524 (EC: IEA); GO_0045505 (EC: IDA); GO_0046825 (EC: IMP, PMID: 15654337); GO_0046902 (EC: IEA); GO_0047496 (EC: IMP); GO_0048167 (EC: IEA); GO_0048341 (EC: IEA); GO_0048487 (EC: IDA, PMID: 11870213); GO_0048513 (EC: IBA); GO_0048666 (EC: IEA); GO_0050809 (EC: IEA); GO_0051402 (EC: IEA); GO_0051592 (EC: IEA); GO_0051881 (EC: IEA); GO_0051938 (EC: IEA); GO_0055072 (EC: IEA); GO_2001237 (EC: IMP, PMID: 19240112) PMID: 1302016; 7477378; 7568002; 7647777; 7748555; 7759106; 7774020; 7903579; 7951324; 8162057; 8197474; 8458085; 8612237; 8696339; 8702625; 9079622; 9147654; 9152833; 9454836; 9466992; 9535906; 9599014; 9668110; 9700202; 9778247; 9809064; 10332029; 10353249; 10410676; 10434301; 10441327; 10770929; 10801775; 10823891; 10958656; 10974549; 11008591; 11013077; 11035034; 11063258; 11092755; 11105061; 11121205; 11137014; 11149616; 11172033; 11264541; 11319238; 11379408; 11432963; 11442349; 11461154; 11468270; 11487199; 11595021; 11607033; 11642542; 11738012; 11739372; 11745989; 11788820; 11792860; 11807410; 11839795; 11854752; 11870213; 11906693; 11939977; 11971872; 11973620; 11988536; 12062094; 12135980; 12191472; 12204002; 12354289; 12354780; 12379151; 12393306; 12393793; 12417652; 12427879; 12456676; 12466534; 12477932; 12548366; 12555240; 12569151; 12604778; 12657678; 12682342; 12783847; 12784292; 12799135; 12807877; 12810713; 12824708; 12873381; 12881483; 12881722; 12952868; 12956863; 14527999; 14570710; 14570907; 14572927; 14617779; 14657499; 14713958; 14714490; 14743370; 14978262; 14985437; 15032971; 15064418; 15140195; 15140196; 15163634; 15225551; 15240759; 15261377; 15273431; 15312898; 15316797; 15338298; 15340079; 15351733; 15359012; 15371500; 15383276; 15468075; 15496672; 15603740; 15610167; 15654337; 15689617; 15716522; 15717026; 15809304; 15815621; 15832309; 15837803; 15843398; 15890517; 15911879; 15916486; 15936278; 15951191; 15994095; 15996546; 16006135; 16085648; 16091361; 16115810; 16115812; 16162412; 16169070; 16183657; 16192271; 16204350; 16278683; 16286508; 16324236; 16365166; 16391387; 16417581; 16452635; 16456924; 16473015; 16492755; 16522639; 16595690; 16606912; 16729030; 16777606; 16782707; 16835690; 16968735; 16973623; 17012230; 17098699; 17115386; 17124493; 17126554; 17135277; 17141218; 17151278; 17161366; 17189290; 17201528; 17208201; 17240517; 17276991; 17299753; 17361007; 17403029; 17409200; 17433700; 17500595; 17519223; 17548833; 17603015; 17610899; 17611284; 17660463; 17687393; 17704510; 17708681; 17902043; 17941857; 17947297; 17948889; 17952586; 17975550; 17989880; 18006506; 18029348; 18029446; 18063376; 18065495; 18068007; 18078716; 18091069; 18157708; 18166084; 18255062; 18267960; 18337408; 18380890; 18400894; 18445618; 18504298; 18558632; 18586675; 18632688; 18640989; 18649400; 18651325; 18669659; 18718937; 18772195; 18831068; 18922795; 18981372; 18986984; 18992820; 19018245; 19026253; 19027857; 19039036; 19059613; 19115052; 19130884; 19133136; 19196932; 19204007; 19240033; 19240112; 19249009; 19250382; 19266143; 19268537; 19270310; 19270701; 19289118; 19361448; 19386911; 19451134; 19488402; 19492089; 19498170; 19525941; 19566678; 19628478; 19656852; 19661690; 19667213; 19710014; 19726651; 19748341; 19752198; 19776381; 19915590; 19916101; 19933700; 19969308; 20016493; 20016831; 20018729; 20026071; 20026656; 20056037; 20064390; 20097678; 20126661; 20140226; 20145253; 20154145; 20204693; 20232225; 20301482; 20360314; 20379614; 20417604; 20444706; 20494921; 20531388; 20708032; 20710011; 20800603; 20858895; 20864123; 20864533; 20875859; 21044956; 21087194; 21139048; 21147489; 21169558; 21177255; 21192926; 21209075; 21245084; 21248742; 21257639; 21280221; 21310951; 21315254; 21320997; 21322024; 21336284; 21364626; 21454471; 21458571; 21465263; 21482444; 21501628; 21509658; 21515588; 21518730; 21519949; 21540131; 21566141; 21685499; 21875723; 21887328; 21889504; 21889981; 21890473; 21896647; 21954231; 21968397; 21971427; 21983719; 21984825; 21985783; 21997870; 22011578; 22048026; 22072510; 22100810; 22101303; 22103299; 22110140; 22119730; 22123826; 22162197; 22178474; 22178478; 22179316; 22219281; 22234237; 22235343; 22306231; 22306738; 22337954; 22352297; 22359536; 22375012; 22399227; 22409360; 22422149; 22433867; 22445760; 22505724; 22511757; 22536159; 22556411; 22573320; 22580459; 22623107; 22642889; 22735540; 22801429; 22815947; 22863883; 22891683; 22906125; 22917585; 22974559; 22984513; 23000965; 23012356; 23051704; 23071649; 23115180; 23160193; 23190281; 23225006; 23275563; 23297360; 23300147; 23305455; 23315009; 23319588; 23339311; 23370273; 23383273; 23443539; 23575829; 23583659; 23624566; 23768628; 23774650; 23898200; 23908352; 23966247; 23980182; 24081492; 24196953; 24199621; 24291262; 24314096; 24412307 huntingtin Ensembl:ENSG00000197386 HGNC:4851 HPRD:00883 MIM:613004 Vega:OTTHUMG00000159916 HTT Bin Zhao, Yue Liu, Oliver He ARIA GGF GGF2 HGL HRG HRG1 HRGA MST131 NDF SMDF WEB: http://www.ncbi.nlm.nih.gov/gene NRG1 neuregulin 1 3084 8p12 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0000165 (EC: IEA); GO_0000902 (EC: IEA); GO_0003161 (EC: IEA); GO_0003222 (EC: IDA, PMID: 17336907); GO_0003712 (EC: IDA, PMID: 15073182); GO_0005102 (EC: IPI, PMID: 7514177); GO_0005125 (EC: TAS, PMID: 10372964); GO_0005176 (EC: IEA); GO_0005515 (EC: IPI, PMID: 7592681); GO_0005576 (EC: NAS, PMID: 1348215); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 11389077); GO_0005634 (EC: IEA); GO_0005737 (EC: IEA); GO_0005887 (EC: IEA); GO_0007154 (EC: TAS, PMID: 17432114); GO_0007169 (EC: IDA, PMID: 7514177); GO_0007171 (EC: IDA, PMID: 9553078); GO_0007171 (EC: NAS, PMID: 1348215); GO_0007173 (EC: TAS); GO_0007399 (EC: TAS, PMID: 17432114); GO_0007416 (EC: IEA); GO_0007422 (EC: IEA); GO_0007626 (EC: IEA); GO_0008083 (EC: IDA, PMID: 11389077); GO_0008083 (EC: NAS, PMID: 8096067); GO_0008283 (EC: IDA, PMID: 11389077); GO_0008543 (EC: TAS); GO_0009790 (EC: IEA); GO_0010667 (EC: IDA, PMID: 9553078); GO_0014032 (EC: TAS, PMID: 17432114); GO_0016020 (EC: NAS, PMID: 8096067); GO_0016324 (EC: IDA, PMID: 12646923); GO_0016477 (EC: IEA); GO_0021781 (EC: IEA); GO_0030296 (EC: IDA, PMID: 7556068); GO_0030297 (EC: IC, PMID: 9553078); GO_0030297 (EC: NAS, PMID: 1348215); GO_0030307 (EC: IDA, PMID: 9553078); GO_0030424 (EC: IEA); GO_0030879 (EC: TAS, PMID: 17432114); GO_0030971 (EC: NAS, PMID: 1348215); GO_0031594 (EC: IEA); GO_0038095 (EC: TAS); GO_0038127 (EC: IDA, PMID: 11389077); GO_0042060 (EC: IDA, PMID: 12646923); GO_0042060 (EC: TAS, PMID: 16412517); GO_0042177 (EC: IEA); GO_0043125 (EC: IDA, PMID: 7556068); GO_0043125 (EC: IPI, PMID: 11389077); GO_0043496 (EC: TAS, PMID: 16412517); GO_0043497 (EC: IDA, PMID: 10559227); GO_0043624 (EC: IGI, PMID: 15155732); GO_0045087 (EC: TAS); GO_0045213 (EC: IEA); GO_0045785 (EC: IDA, PMID: 7556068); GO_0045892 (EC: IDA, PMID: 15073182); GO_0046579 (EC: IEA); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0048663 (EC: IEA); GO_0051048 (EC: IDA, PMID: 10559227); GO_0051155 (EC: ISS); GO_0051897 (EC: IEA); GO_0055007 (EC: ISS); GO_0055012 (EC: IDA, PMID: 9553078); GO_0060045 (EC: IDA, PMID: 9553078); GO_0060379 (EC: IDA, PMID: 17336907); GO_0060956 (EC: IDA, PMID: 17336907); GO_0061098 (EC: IDA, PMID: 7556068); GO_2001240 (EC: IDA, PMID: 9553078) PMID: 1348215; 1350381; 7509448; 7514177; 7556068; 7592681; 7689552; 7721889; 7730382; 7782315; 7876250; 7903175; 8062828; 8095334; 8096067; 8125298; 8325659; 8702572; 9168114; 9168115; 9333014; 9342050; 9553078; 9565587; 9685409; 10372964; 10523851; 10537356; 10559227; 10585499; 10597312; 11116142; 11389077; 11555649; 11896060; 12082616; 12145742; 12204892; 12471041; 12477932; 12478479; 12509456; 12528817; 12556556; 12600989; 12646923; 12768307; 12800145; 12808428; 12874607; 14569272; 14632199; 14647391; 14699424; 14702039; 14729827; 14966480; 15007393; 15073182; 15155732; 15159416; 15162166; 15197397; 15219675; 15248869; 15276238; 15303101; 15326116; 15466169; 15489334; 15494726; 15498868; 15527969; 15538186; 15545978; 15584912; 15609326; 15645137; 15703820; 15897877; 15939841; 16082692; 16155362; 16158055; 16189508; 16219117; 16219118; 16249994; 16287046; 16326006; 16344560; 16412517; 16428439; 16442083; 16446404; 16470843; 16483744; 16520822; 16526041; 16618933; 16638076; 16687441; 16690615; 16730337; 16767099; 16825199; 16867224; 16868568; 16891421; 16940976; 17033632; 17072305; 17214955; 17275115; 17300918; 17336907; 17336946; 17366345; 17405926; 17408693; 17432114; 17447867; 17499242; 17503451; 17519028; 17562386; 17565985; 17598910; 17602072; 17631867; 17652086; 17884806; 17901998; 17903296; 17925794; 17941827; 17962208; 18032396; 18159252; 18180429; 18193072; 18198266; 18234478; 18255317; 18282690; 18286587; 18291420; 18395550; 18455303; 18455369; 18466879; 18466881; 18470533; 18494263; 18494554; 18497096; 18516516; 18543275; 18571900; 18583979; 18584117; 18585932; 18606232; 18668031; 18704261; 18714568; 18728681; 18798975; 18799465; 18806920; 19054571; 19058791; 19086053; 19127563; 19148499; 19150438; 19156152; 19184335; 19196962; 19199244; 19229203; 19269083; 19306381; 19328558; 19339916; 19350564; 19367581; 19367584; 19394386; 19439994; 19448847; 19449332; 19497323; 19521112; 19545856; 19556605; 19569180; 19573260; 19575259; 19594860; 19597049; 19626024; 19644050; 19652122; 19659570; 19733651; 19736351; 19782967; 19797898; 19801490; 19802002; 19913121; 19913623; 19937977; 19965935; 19967439; 20036336; 20061032; 20102668; 20182055; 20215529; 20218976; 20227043; 20371257; 20374152; 20379614; 20427670; 20435087; 20472376; 20497232; 20520724; 20526724; 20580130; 20582876; 20625696; 20628086; 20638435; 20671236; 20682778; 20736300; 20800603; 20921115; 20926259; 20927045; 20978455; 21035784; 21041608; 21057508; 21127983; 21234898; 21239627; 21246584; 21247898; 21283760; 21368034; 21371516; 21437657; 21467033; 21512575; 21546767; 21555713; 21576249; 21653853; 21706185; 21716252; 21745728; 21792199; 21840482; 21858616; 21865659; 21965611; 22019858; 22027878; 22042562; 22052506; 22158511; 22183611; 22200588; 22209534; 22216327; 22226049; 22226548; 22249266; 22249457; 22267200; 22350758; 22377709; 22378022; 22378872; 22414959; 22425775; 22467496; 22494484; 22504067; 22520967; 22563075; 22574178; 22590542; 22613991; 22739235; 22790889; 22832904; 22886427; 22891299; 22944276; 22968213; 22974608; 22999558; 23032943; 23035098; 23104879; 23148218; 23213231; 23247143; 23253390; 23301017; 23308187; 23328545; 23360725; 23399902; 23400839; 23408906; 23468880; 23480537; 23489597; 23524320; 23572145; 23590603; 23625463; 23632455; 23739962; 23870195; 23934736; 23937725; 24097984; 24112719 neuregulin 1 Ensembl:ENSG00000157168 HGNC:7997 HPRD:00802 MIM:142445 Vega:OTTHUMG00000163918 NRG1 Bin Zhao, Yue Liu, Oliver He HIF-1A HIF-1alpha HIF1 HIF1-ALPHA MOP1 PASD8 bHLHe78 WEB: http://www.ncbi.nlm.nih.gov/gene HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 3091 14q23.2 20140408 9606 14 protein-coding Official from a nomenclature committee GO_0000989 (EC: IDA); GO_0001076 (EC: IEA); GO_0001077 (EC: IEA); GO_0001525 (EC: IEA); GO_0001666 (EC: IDA, PMID: 11782478); GO_0001666 (EC: IMP, PMID: 12411310); GO_0001755 (EC: IEA); GO_0001837 (EC: ISS, PMID: 18037992); GO_0001892 (EC: IEA); GO_0001922 (EC: IEA); GO_0001938 (EC: IC, PMID: 8756616); GO_0001947 (EC: IEA); GO_0002052 (EC: IEA); GO_0002248 (EC: ISS, PMID: 18037992); GO_0003151 (EC: IEA); GO_0003208 (EC: IEA); GO_0003700 (EC: IDA, PMID: 11782478); GO_0003700 (EC: TAS, PMID: 15261140); GO_0003705 (EC: IDA, PMID: 8387214); GO_0003705 (EC: IDA, Qualifier: contributes_to, PMID: 7539918); GO_0004871 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12004076); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005667 (EC: IPI, PMID: 9576906); GO_0005730 (EC: IDA); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0006089 (EC: IEA); GO_0006355 (EC: IDA, PMID: 11782478); GO_0006879 (EC: IEA); GO_0007165 (EC: IMP, PMID: 12411310); GO_0007219 (EC: TAS); GO_0007595 (EC: IEA); GO_0008134 (EC: IPI, PMID: 7539918); GO_0008542 (EC: IEA); GO_0010468 (EC: IDA, PMID: 18419598); GO_0010573 (EC: IDA, PMID: 12958148); GO_0010575 (EC: IDA, PMID: 8756616); GO_0010575 (EC: IMP, PMID: 18658046); GO_0010634 (EC: ISS, PMID: 18037992); GO_0010870 (EC: IMP, PMID: 17178876); GO_0014850 (EC: IEA); GO_0019896 (EC: IMP, PMID: 19528298); GO_0019899 (EC: IPI, PMID: 11641274); GO_0019901 (EC: IPI); GO_0021502 (EC: IEA); GO_0021987 (EC: IEA); GO_0030502 (EC: IEA); GO_0030949 (EC: IC, PMID: 12958148); GO_0031514 (EC: IEA); GO_0031625 (EC: IPI, PMID: 11641274); GO_0032007 (EC: IEA); GO_0032364 (EC: IDA, PMID: 16956324); GO_0032722 (EC: TAS, PMID: 18370914); GO_0032909 (EC: IMP, PMID: 12411310); GO_0032963 (EC: ISS, PMID: 18037992); GO_0035035 (EC: IPI, PMID: 15261140); GO_0035162 (EC: IEA); GO_0035257 (EC: IPI, PMID: 18658046); GO_0035774 (EC: IEA); GO_0042541 (EC: IEA); GO_0042593 (EC: IEA); GO_0042789 (EC: IC, PMID: 7539918); GO_0042826 (EC: IEA); GO_0043524 (EC: IEA); GO_0043565 (EC: IDA, Qualifier: contributes_to, PMID: 7539918); GO_0043619 (EC: IDA, PMID: 8089148); GO_0044212 (EC: IDA); GO_0045648 (EC: IC, PMID: 1448077); GO_0045766 (EC: IC, PMID: 8756616); GO_0045821 (EC: IC, PMID: 8089148); GO_0045893 (EC: IDA, PMID: 8089148); GO_0045893 (EC: IMP); GO_0045926 (EC: IEA); GO_0045944 (EC: IDA, PMID: 11573933); GO_0045944 (EC: IGI, PMID: 17981124); GO_0046716 (EC: IEA); GO_0046886 (EC: IDA, PMID: 1448077); GO_0046982 (EC: IPI, PMID: 12239177); GO_0046982 (EC: TAS, PMID: 15261140); GO_0048546 (EC: IEA); GO_0051000 (EC: TAS, PMID: 18254728); GO_0051216 (EC: IEA); GO_0051541 (EC: ISS, PMID: 18037992); GO_0051879 (EC: IDA, PMID: 9079689); GO_0060574 (EC: IEA); GO_0061030 (EC: IEA); GO_0061298 (EC: IEA); GO_0061418 (EC: TAS); GO_0061419 (EC: IDA); GO_0061419 (EC: IMP, PMID: 19652095); GO_0070101 (EC: IC, PMID: 17178876); GO_0070244 (EC: IEA); GO_0071347 (EC: IEP, PMID: 12958148); GO_0071456 (EC: IDA, PMID: 11573933); GO_0071456 (EC: IEP); GO_0071456 (EC: TAS); GO_0071542 (EC: IEA); GO_2001054 (EC: IEA) PMID: 1448077; 7539918; 7836384; 8089148; 8107114; 8387214; 8663540; 8753788; 8756616; 8786149; 8816435; 8927054; 9079689; 9235919; 9537326; 9576906; 9653127; 9704006; 9782081; 9822602; 9828130; 9887100; 9923855; 10202154; 10353251; 10425220; 10551817; 10594042; 10640274; 10702253; 10758161; 10777486; 10823831; 10878807; 10903152; 10906065; 10944113; 10950862; 10961998; 10973499; 11006129; 11024059; 11089639; 11226425; 11278891; 11292861; 11292862; 11331613; 11358837; 11382768; 11389899; 11486006; 11504942; 11566883; 11573933; 11593383; 11598268; 11641274; 11707426; 11726537; 11734856; 11739718; 11782478; 11823643; 11852072; 11861398; 11865071; 11868612; 11886167; 11940656; 11943784; 11959977; 11959990; 11971899; 11980639; 11986208; 11992540; 12004076; 12016145; 12042299; 12050673; 12062197; 12080085; 12084725; 12086861; 12099689; 12114320; 12123724; 12124396; 12136249; 12149254; 12154057; 12202863; 12205091; 12207089; 12209691; 12213597; 12213806; 12215445; 12228247; 12237125; 12239177; 12242281; 12296651; 12351678; 12376345; 12401798; 12411310; 12446723; 12451989; 12464182; 12468553; 12477932; 12482756; 12482858; 12485908; 12485909; 12488445; 12538644; 12560087; 12586627; 12586829; 12588875; 12606543; 12606552; 12632503; 12651620; 12670503; 12673675; 12682018; 12697836; 12727858; 12743597; 12761217; 12764143; 12778114; 12781449; 12808024; 12810083; 12821113; 12823854; 12855680; 12858534; 12865501; 12871382; 12876287; 12883692; 12885785; 12900407; 12912907; 12914933; 12914934; 12919954; 12925778; 12937141; 12944107; 12958148; 12966423; 14512791; 14521712; 14523474; 14556007; 14559790; 14600153; 14636255; 14638687; 14645546; 14657004; 14662854; 14671307; 14672622; 14680803; 14680833; 14681237; 14691445; 14699081; 14702039; 14712484; 14726529; 14729605; 14734545; 14742449; 14744756; 14744852; 14757845; 14981919; 15024076; 15024078; 15031145; 15060148; 15062033; 15064771; 15071503; 15082527; 15082785; 15084243; 15084514; 15111179; 15135259; 15135470; 15146197; 15147973; 15154850; 15155569; 15156561; 15160341; 15169887; 15170665; 15175080; 15191555; 15199114; 15199132; 15199161; 15217953; 15240510; 15240563; 15247232; 15252039; 15261140; 15280364; 15280370; 15319539; 15322093; 15328163; 15331549; 15342390; 15342781; 15347669; 15350301; 15374877; 15382039; 15385570; 15388333; 15465032; 15466858; 15474027; 15474452; 15475194; 15479785; 15485863; 15489334; 15489637; 15492789; 15538748; 15543236; 15556623; 15561954; 15598682; 15598882; 15611046; 15611064; 15615775; 15623945; 15629713; 15652751; 15656883; 15665520; 15669079; 15674338; 15696961; 15709180; 15718424; 15721254; 15735682; 15741220; 15750626; 15770733; 15776016; 15780936; 15805230; 15805242; 15809750; 15811877; 15814637; 15831177; 15832512; 15838297; 15838334; 15850830; 15862159; 15862307; 15864753; 15876874; 15878343; 15897903; 15902299; 15935515; 15947089; 15962286; 15964822; 15967109; 15970466; 15978586; 15983061; 15987493; 15987702; 15994306; 16005427; 16007214; 16011198; 16035955; 16046581; 16100168; 16109785; 16110315; 16136272; 16136514; 16139409; 16140212; 16142350; 16144691; 16149050; 16157596; 16161047; 16168127; 16170370; 16189514; 16195397; 16205110; 16208522; 16227395; 16229017; 16229182; 16242072; 16246222; 16253768; 16261165; 16263938; 16278378; 16278385; 16284786; 16288478; 16288748; 16304044; 16331995; 16337862; 16338068; 16341243; 16344560; 16396931; 16407130; 16407835; 16408279; 16421254; 16424018; 16438736; 16452478; 16482104; 16490744; 16506055; 16507982; 16511565; 16515634; 16516166; 16516853; 16533170; 16543236; 16543242; 16543245; 16552335; 16554418; 16555123; 16579968; 16596228; 16611863; 16612574; 16627691; 16629644; 16631533; 16638120; 16682946; 16721291; 16735500; 16736613; 16738327; 16756955; 16760477; 16768548; 16769565; 16775626; 16775835; 16777103; 16779673; 16815840; 16826425; 16826581; 16828081; 16837101; 16847054; 16849522; 16854377; 16865676; 16871792; 16873253; 16883594; 16885164; 16890383; 16899596; 16899602; 16901993; 16920734; 16937436; 16951198; 16951228; 16954218; 16956324; 16969516; 16970912; 16979927; 16998808; 17010341; 17015263; 17015745; 17024177; 17043658; 17045016; 17047048; 17055760; 17060326; 17060462; 17066447; 17067582; 17075581; 17077301; 17097563; 17097641; 17102128; 17102633; 17132228; 17135241; 17143338; 17178876; 17179985; 17189520; 17220880; 17236590; 17237281; 17244529; 17245699; 17268888; 17273746; 17289019; 17289897; 17290185; 17292638; 17294729; 17307335; 17310851; 17320759; 17325032; 17335808; 17336340; 17339318; 17343848; 17360382; 17362638; 17376295; 17382205; 17382325; 17387384; 17400550; 17403672; 17404022; 17407091; 17418410; 17418790; 17418979; 17426247; 17426252; 17437013; 17438103; 17439941; 17442277; 17442736; 17445471; 17451682; 17452775; 17458899; 17461470; 17473988; 17474992; 17477366; 17482131; 17487356; 17488873; 17490410; 17495954; 17502379; 17507435; 17511040; 17519536; 17519789; 17525282; 17532031; 17536453; 17544543; 17545054; 17555795; 17558023; 17562539; 17562866; 17563752; 17568584; 17570486; 17591803; 17592963; 17595907; 17597020; 17606258; 17617866; 17624927; 17634230; 17637739; 17640715; 17650819; 17653093; 17662481; 17666400; 17674038; 17676480; 17684492; 17713282; 17714861; 17718430; 17721610; 17725546; 17726031; 17785433; 17805961; 17822384; 17826745; 17828303; 17848618; 17852557; 17875644; 17881647; 17889387; 17891484; 17893997; 17898080; 17903293; 17916562; 17927572; 17932327; 17938407; 17942596; 17947829; 17956732; 17965024; 17967865; 17967866; 17967880; 17973296; 17978497; 17981124; 17982282; 17984117; 17986458; 17989922; 17990984; 17999410; 18000826; 18006690; 18021370; 18024476; 18024825; 18025805; 18029348; 18030615; 18031949; 18035072; 18037992; 18047470; 18050215; 18050252; 18055454; 18060642; 18062281; 18065728; 18081507; 18083891; 18094421; 18097583; 18154573; 18159247; 18160046; 18163427; 18166158; 18172210; 18172309; 18172354; 18178340; 18184809; 18184961; 18199003; 18209490; 18221327; 18222538; 18225753; 18239067; 18240292; 18246800; 18250065; 18254728; 18256363; 18258605; 18264140; 18269201; 18279708; 18290322; 18292935; 18294451; 18295594; 18297062; 18299578; 18305400; 18307947; 18307948; 18309031; 18313384; 18314489; 18315897; 18323857; 18325389; 18339685; 18342368; 18347341; 18351386; 18354193; 18362831; 18365547; 18370914; 18370960; 18376310; 18381294; 18381358; 18384112; 18385176; 18393939; 18398039; 18411415; 18413745; 18418234; 18419598; 18422279; 18422749; 18424433; 18424783; 18426857; 18440561; 18447926; 18452596; 18459144; 18462799; 18465238; 18473128; 18476562; 18476629; 18476949; 18484090; 18493321; 18506785; 18521687; 18528739; 18533565; 18538669; 18546529; 18551130; 18554951; 18561315; 18563339; 18563715; 18570733; 18574470; 18588890; 18592007; 18593917; 18595517; 18606657; 18617693; 18619649; 18621534; 18630523; 18632605; 18638657; 18641302; 18644974; 18648372; 18655183; 18658046; 18687685; 18694926; 18703592; 18704463; 18713068; 18713836; 18718909; 18720385; 18727515; 18728026; 18762723; 18763582; 18772337; 18775313; 18779379; 18780286; 18781797; 18784753; 18785001; 18787502; 18790175; 18790176; 18792019; 18799519; 18813785; 18832593; 18834862; 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22927657; 22931643; 22932900; 22936443; 22937154; 22945272; 22946054; 22946320; 22948784; 22952674; 22960198; 22964004; 22970168; 22971010; 22977270; 22977664; 22986049; 22991450; 22992985; 23008060; 23013270; 23020605; 23023480; 23028863; 23028920; 23029528; 23030583; 23034156; 23038967; 23042279; 23042446; 23047702; 23052192; 23053140; 23059773; 23059786; 23060442; 23063455; 23065176; 23065205; 23082126; 23084780; 23087365; 23093058; 23097160; 23123196; 23131565; 23142284; 23144021; 23160040; 23160373; 23161568; 23181555; 23185316; 23185562; 23194660; 23196386; 23220088; 23221556; 23225420; 23228635; 23237807; 23246962; 23248117; 23263636; 23266008; 23269488; 23275444; 23303559; 23326384; 23328582; 23331791; 23333658; 23334958; 23335846; 23336375; 23339102; 23342109; 23344526; 23358852; 23368766; 23372804; 23375385; 23375698; 23381944; 23387829; 23388440; 23389731; 23398456; 23401859; 23404377; 23405012; 23409121; 23409769; 23410250; 23413029; 23421024; 23423382; 23445622; 23449350; 23454212; 23456821; 23457305; 23462604; 23467940; 23474946; 23475391; 23476056; 23481058; 23485997; 23492195; 23496980; 23513056; 23517877; 23523960; 23526216; 23526365; 23526997; 23529663; 23530034; 23530843; 23538299; 23541582; 23545606; 23549681; 23550771; 23551342; 23562913; 23563312; 23567513; 23580587; 23581228; 23583797; 23587905; 23588703; 23593116; 23601303; 23611775; 23615397; 23618863; 23623921; 23639975; 23645672; 23649089; 23661177; 23667251; 23671189; 23671581; 23695013; 23704921; 23711352; 23722539; 23723982; 23746844; 23747271; 23749907; 23750001; 23760768; 23764844; 23767832; 23778527; 23785417; 23787140; 23791554; 23792163; 23799043; 23811286; 23836663; 23840432; 23840602; 23857282; 23862672; 23869589; 23870462; 23872148; 23872956; 23879962; 23880665; 23880760; 23886153; 23886154; 23886195; 23886708; 23897427; 23900566; 23911400; 23912593; 23916472; 23924606; 23928864; 23930677; 23935399; 23936170; 23946285; 23950980; 23959876; 23966163; 23979441; 23991975; 23992143; 23999440; 24015760; 24016866; 24033233; 24042437; 24067372; 24071737; 24090974; 24096035; 24127318; 24164895; 24176785; 24195510; 24197448; 24220190; 24232601; 24316222; 24324133; 24333432; 24344197; 24344305; 24374034; 24374892; 24391213; 24434214 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Ensembl:ENSG00000100644 HGNC:4910 HPRD:04517 MIM:603348 Vega:OTTHUMG00000140344 HIF1A Bin Zhao, Yue Liu, Oliver He HLA-DRB WEB: http://www.ncbi.nlm.nih.gov/gene HLA-DRB5 major histocompatibility complex, class II, DR beta 5 3127 hCG_1998957 6p21.3 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000139 (EC: TAS); GO_0002381 (EC: ISS); GO_0002437 (EC: ISS); GO_0002455 (EC: ISS); GO_0005765 (EC: IDA, PMID: 18305173); GO_0005765 (EC: TAS); GO_0005886 (EC: TAS); GO_0006955 (EC: ISS); GO_0009897 (EC: ISS); GO_0012507 (EC: TAS); GO_0016045 (EC: ISS); GO_0019221 (EC: TAS); GO_0019886 (EC: TAS); GO_0030658 (EC: TAS); GO_0030666 (EC: TAS); GO_0030669 (EC: TAS); GO_0031295 (EC: TAS); GO_0031902 (EC: IDA, PMID: 18305173); GO_0032588 (EC: TAS); GO_0032673 (EC: ISS); GO_0032689 (EC: ISS); GO_0035774 (EC: ISS); GO_0042088 (EC: ISS); GO_0042130 (EC: ISS); GO_0042605 (EC: ISS); GO_0042613 (EC: IEA); GO_0050852 (EC: TAS); GO_0051262 (EC: ISS); GO_0060333 (EC: TAS); GO_0070062 (EC: IDA, PMID: 12519789); GO_0071556 (EC: TAS); GO_2001179 (EC: ISS) PMID: 1428007; 1612646; 1869305; 1905983; 1967269; 1970352; 1975801; 1978941; 2023919; 2212675; 2471740; 2511168; 2543930; 2565895; 2846691; 2884201; 2885840; 3015788; 3020127; 3099214; 3129499; 3137159; 3259543; 3371836; 3456344; 3466180; 3476943; 3489470; 3571980; 7512597; 7541827; 7547576; 7602119; 7645219; 7652736; 7734415; 7974469; 8016840; 8026992; 8084338; 8168144; 8168862; 8362413; 8376762; 8450224; 8462990; 8655358; 8864175; 8988548; 9027973; 9079699; 9162096; 9223324; 9226128; 9349614; 9500545; 9777332; 9820607; 9864034; 10551425; 10609818; 10661406; 10703621; 10729169; 11034591; 11048639; 11082515; 11082517; 11118314; 11144300; 11169266; 11181188; 11181995; 11260517; 11380955; 11469465; 11555411; 11704801; 11751963; 11782380; 11798795; 11827988; 11934390; 11972886; 11997714; 12028548; 12121280; 12133402; 12144077; 12144632; 12202216; 12209103; 12230470; 12244309; 12296785; 12358860; 12392858; 12427289; 12477932; 12519789; 12652907; 12694574; 12694577; 12956878; 14508706; 14617041; 14752708; 14989721; 15191532; 15191533; 15245378; 15489916; 15730527; 15784911; 15896200; 15902698; 15982265; 16140993; 16305688; 16405603; 16426242; 16441501; 16566202; 16916662; 16973583; 17106278; 17153701; 17182961; 17207965; 17411376; 17431094; 17507489; 17559577; 17652306; 17910142; 17959659; 18305173; 18520346; 18569076; 18672082; 18713991; 18832704; 18846964; 18945465; 19116923; 19122664; 19223392; 19235017; 19380721; 19449444; 19620308; 19663932; 19770068; 19811438; 20012522; 20193235; 20193583; 20307907; 20394989; 20458337; 20606439; 20639878; 21085635; 21131588; 21297633; 21299892; 21778700; 21906983; 21922073; 22033527; 22493691; 22531795; 22723597; 22808111; 22860026; 22862923; 22888134; 23349640; 23535732; 23850713 major histocompatibility complex, class II, DR beta 5 Ensembl:ENSG00000198502 HGNC:4953 HPRD:09209 MIM:604776 Vega:OTTHUMG00000031027 HLA-DRB5 Bin Zhao, Yue Liu, Oliver He HMG1 HMG3 SBP-1 WEB: http://www.ncbi.nlm.nih.gov/gene HMGB1 high mobility group box 1 3146 RP11-550P23.1 13q12 20140408 9606 13 protein-coding Official from a nomenclature committee GO_0000122 (EC: IMP, PMID: 19158276); GO_0000793 (EC: IDA, PMID: 12925773); GO_0001773 (EC: ISS); GO_0002407 (EC: ISS); GO_0002437 (EC: IEP, PMID: 19841752); GO_0003684 (EC: ISS); GO_0003690 (EC: ISS); GO_0003697 (EC: ISS); GO_0003700 (EC: IDA, PMID: 19223331); GO_0005125 (EC: ISS); GO_0005515 (EC: IPI, PMID: 11748232); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 19841752); GO_0005634 (EC: IDA, PMID: 19223331); GO_0005654 (EC: TAS); GO_0006265 (EC: ISS); GO_0006288 (EC: IDA, PMID: 9600082); GO_0006309 (EC: TAS); GO_0006310 (EC: ISS); GO_0006357 (EC: IDA, PMID: 11748232); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0008134 (EC: IPI, PMID: 19223331); GO_0008301 (EC: IMP, PMID: 19223331); GO_0008301 (EC: ISS); GO_0009986 (EC: IDA, PMID: 19841752); GO_0017053 (EC: IDA, Qualifier: colocalizes_with, PMID: 19158276); GO_0017055 (EC: IDA, PMID: 8006019); GO_0031175 (EC: ISS); GO_0033151 (EC: IDA, PMID: 9166431); GO_0042056 (EC: ISS); GO_0043065 (EC: IDA, PMID: 19800306); GO_0043280 (EC: IDA, PMID: 19800306); GO_0043388 (EC: IDA, PMID: 11748232); GO_0044822 (EC: IDA); GO_0045087 (EC: TAS); GO_0045944 (EC: IDA, PMID: 19223331); GO_0050786 (EC: ISS); GO_0050918 (EC: ISS); GO_0051103 (EC: ISS); GO_0070491 (EC: IPI, PMID: 19223331); GO_2000426 (EC: IEA) PMID: 1909331; 2013279; 2922262; 3697355; 8006019; 8339930; 8366113; 8661151; 8890171; 9036861; 9150946; 9166431; 9472015; 9507007; 9600082; 9628821; 9671457; 9722660; 9812979; 9880542; 10490593; 10531386; 10617144; 10652254; 10962007; 11099378; 11106654; 11246022; 11279268; 11294645; 11299752; 11470162; 11748221; 11748232; 12062430; 12110890; 12149489; 12231511; 12384917; 12456506; 12477932; 12488489; 12517784; 12534345; 12565837; 12591939; 12604365; 12620891; 12665595; 12727838; 12759333; 12785009; 12799451; 12925773; 12935895; 14517071; 14532127; 14534709; 14702039; 14739282; 14999020; 15005629; 15014079; 15130941; 15146429; 15162419; 15201494; 15210788; 15488733; 15489334; 15496585; 15666359; 15733057; 15743787; 15766246; 15793304; 15802534; 15877951; 15915542; 15924431; 15944249; 15994314; 16040616; 16130169; 16169070; 16267105; 16282196; 16570276; 16697213; 16751357; 16802368; 16807371; 16855214; 16916647; 16951227; 16962095; 16966386; 16968820; 16997859; 16997939; 17035340; 17060403; 17142771; 17203009; 17218606; 17346334; 17403666; 17475879; 17502242; 17504981; 17597834; 17610420; 17617154; 17678959; 17895302; 17918013; 17936030; 17958791; 17975708; 17991152; 18029348; 18073062; 18076993; 18160415; 18239618; 18239742; 18250463; 18277058; 18288272; 18294942; 18317568; 18346273; 18354232; 18425372; 18431589; 18441281; 18569640; 18577209; 18599803; 18631454; 18644848; 18655026; 18670905; 18680137; 18682735; 18692049; 18707018; 18715162; 18720262; 18759291; 18768881; 18788635; 18799030; 18822317; 18825489; 18825712; 18846108; 18850631; 18854154; 18949384; 18952078; 18974890; 18984601; 18996119; 19005067; 19009026; 19044016; 19087540; 19139725; 19148477; 19150066; 19151394; 19158276; 19197071; 19201506; 19214652; 19223331; 19247800; 19387923; 19398086; 19417608; 19445369; 19446504; 19451748; 19471022; 19476625; 19505873; 19515846; 19530996; 19533845; 19545550; 19564572; 19571604; 19572890; 19616266; 19639200; 19666121; 19679874; 19726280; 19738201; 19751520; 19777384; 19786934; 19800306; 19811284; 19819342; 19837864; 19841752; 19876719; 19887013; 19930620; 19933377; 19948257; 19962765; 20007974; 20044610; 20110525; 20123074; 20123075; 20123076; 20185963; 20193282; 20195357; 20200191; 20207250; 20231695; 20302902; 20350435; 20360068; 20414834; 20419158; 20430742; 20510002; 20579387; 20622903; 20659154; 20723409; 20799933; 20812762; 20826760; 20844833; 20846416; 20927132; 20936104; 20959471; 20980161; 21042739; 21044333; 21044950; 21052685; 21092200; 21093407; 21099216; 21116278; 21120500; 21139048; 21146549; 21151833; 21163940; 21181308; 21198433; 21211520; 21241404; 21283827; 21303685; 21319273; 21365018; 21366949; 21380479; 21395369; 21435605; 21442152; 21443191; 21457762; 21457800; 21520052; 21532866; 21548924; 21617575; 21617715; 21642542; 21650061; 21656024; 21691146; 21743489; 21752923; 21788990; 21825870; 21860212; 21864037; 21871094; 21890473; 21900206; 21906983; 21914366; 21915243; 21926646; 21940680; 21944254; 21944908; 21947243; 21953322; 21957148; 21958433; 21963094; 21968272; 21989210; 21990362; 22012330; 22020142; 22025513; 22047946; 22102692; 22105604; 22108005; 22110531; 22127462; 22127490; 22189477; 22189943; 22231645; 22237993; 22248244; 22265157; 22275109; 22293756; 22306257; 22331597; 22333024; 22345153; 22348591; 22361176; 22369934; 22370717; 22379092; 22391561; 22394598; 22473704; 22484401; 22496788; 22505724; 22521432; 22544356; 22549180; 22549347; 22552293; 22578261; 22609241; 22623428; 22644337; 22672360; 22696656; 22703527; 22747650; 22750245; 22780932; 22782142; 22842346; 22862965; 22883976; 22884669; 22909167; 22922889; 22928592; 22931605; 22932142; 22939629; 22960399; 22983919; 23000965; 23023232; 23042506; 23055574; 23063560; 23070967; 23118492; 23122444; 23143556; 23157129; 23175347; 23194089; 23204053; 23207101; 23213216; 23228930; 23231044; 23244202; 23255728; 23260004; 23269659; 23269975; 23284878; 23288170; 23317219; 23318458; 23325855; 23328212; 23339448; 23359306; 23384711; 23414695; 23440398; 23447529; 23467607; 23485600; 23549344; 23602568; 23616573; 23628898; 23649808; 23685846; 23691208; 23711070; 23723299; 23727604; 23729200; 23866030; 23883808; 23911608; 23954397; 23964150; 23974442; 24082908; 24133029; 24152844; 24188108; 24200063; 24257755; 24302768 high mobility group box 1 Ensembl:ENSG00000189403 HGNC:4983 HPRD:01228 MIM:163905 Vega:OTTHUMG00000016670 HMGB1 Bin Zhao, Yue Liu, Oliver He LDLCQ3 WEB: http://www.ncbi.nlm.nih.gov/gene HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 3156 5q13.3-q14 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0004420 (EC: IEA); GO_0005515 (EC: IPI); GO_0005778 (EC: IDA, PMID: 17180682); GO_0005783 (EC: IDA, PMID: 17180682); GO_0005789 (EC: TAS, PMID: 2991281); GO_0006695 (EC: TAS); GO_0006743 (EC: IEA); GO_0007568 (EC: IEA); GO_0007584 (EC: IEA); GO_0008299 (EC: IEA); GO_0008542 (EC: IEA); GO_0009790 (EC: IEA); GO_0010664 (EC: IEA); GO_0010666 (EC: IEA); GO_0015936 (EC: IEA); GO_0016021 (EC: IEA); GO_0032874 (EC: IEA); GO_0042282 (EC: IDA, PMID: 2991281); GO_0042803 (EC: IEA); GO_0043407 (EC: IEA); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0045445 (EC: IEA); GO_0045471 (EC: IEA); GO_0045908 (EC: IEA); GO_0048643 (EC: IEA); GO_0048661 (EC: IEA); GO_0050662 (EC: IDA, PMID: 10698924); GO_0051262 (EC: IDA, PMID: 10698924); GO_0061045 (EC: IEA); GO_0061179 (EC: IEA); GO_0070374 (EC: IEA); GO_0070402 (EC: IDA, PMID: 10698924) PMID: 1755834; 1979742; 2369897; 2991281; 2998972; 3308873; 3860301; 3866240; 3896758; 6479432; 6491541; 8028508; 8406993; 9853754; 10391209; 10449533; 10695663; 10698924; 11349148; 11716764; 11894121; 12213890; 12477733; 12477932; 12535518; 12778445; 12803139; 12860252; 12871602; 14556080; 14563840; 14684825; 14697242; 15090540; 15146197; 15199031; 15233402; 15473258; 15489334; 15811249; 16014965; 16054061; 16168377; 16196087; 16515720; 16930778; 17180682; 17284348; 17502376; 17652086; 17681147; 17855807; 17870053; 18024962; 18056971; 18193044; 18261733; 18332269; 18354102; 18459144; 18559695; 18622260; 18660489; 18676680; 18787507; 18802019; 18815589; 18996102; 19053857; 19060906; 19060911; 19067673; 19088433; 19148283; 19170196; 19197348; 19327767; 19336370; 19446537; 19458199; 19460711; 19554360; 19558216; 19625176; 19667110; 19692168; 19773416; 19887822; 19906111; 19913121; 19923996; 19948975; 20031551; 20031582; 20031591; 20145341; 20167577; 20235787; 20388088; 20403997; 20409966; 20413733; 20450896; 20458442; 20540816; 20571754; 20578904; 20602615; 20628086; 20679960; 20686565; 20691829; 20864672; 20935630; 20972250; 21139048; 21145461; 21262914; 21343306; 21355415; 21360500; 21427285; 21433257; 21530605; 21778231; 21799150; 21801748; 21890473; 21906983; 21909109; 21944868; 21963094; 21987572; 22024489; 22053931; 22143767; 22177940; 22505724; 22858685; 23000965; 23223569; 23642566; 23933271; 24025715; 24233489; 24371122 3-hydroxy-3-methylglutaryl-CoA reductase Ensembl:ENSG00000113161 HGNC:5006 HPRD:00836 MIM:142910 Vega:OTTHUMG00000102069 HMGCR Bin Zhao, Yue Liu, Oliver He HMOX1D HO-1 HSP32 bK286B10 WEB: http://www.ncbi.nlm.nih.gov/gene HMOX1 heme oxygenase (decycling) 1 3162 CTA-286B10.6 22q13.1 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0001525 (EC: TAS, PMID: 12239590); GO_0001935 (EC: TAS, PMID: 12239590); GO_0002246 (EC: IMP, PMID: 9884342); GO_0002686 (EC: TAS, PMID: 14525760); GO_0004392 (EC: IDA, PMID: 17915953); GO_0004392 (EC: IMP, PMID: 19556236); GO_0004630 (EC: IEA); GO_0004871 (EC: IMP, PMID: 12761501); GO_0005615 (EC: TAS, PMID: 18307065); GO_0005634 (EC: ISS); GO_0005730 (EC: IEA); GO_0005783 (EC: IDA, PMID: 19556236); GO_0005783 (EC: ISS); GO_0005789 (EC: TAS); GO_0005829 (EC: IEA); GO_0005901 (EC: IEA); GO_0006778 (EC: TAS); GO_0006788 (EC: IDA, PMID: 17915953); GO_0006879 (EC: TAS); GO_0006979 (EC: IMP, PMID: 9884342); GO_0007264 (EC: IEA); GO_0007588 (EC: IC, PMID: 17915953); GO_0008217 (EC: IEA); GO_0008219 (EC: ISS); GO_0008630 (EC: IEA); GO_0010656 (EC: IEA); GO_0014806 (EC: TAS, PMID: 18289072); GO_0016020 (EC: TAS, PMID: 3345742); GO_0019899 (EC: ISS, PMID: 15516695); GO_0020037 (EC: IDA, PMID: 17915953); GO_0031670 (EC: IEA); GO_0032764 (EC: IEA); GO_0034101 (EC: IMP, PMID: 9884342); GO_0034383 (EC: TAS, PMID: 9884342); GO_0035094 (EC: IDA, PMID: 18205746); GO_0035556 (EC: TAS, PMID: 17652371); GO_0042167 (EC: IDA, PMID: 17915953); GO_0042167 (EC: TAS); GO_0042542 (EC: ISS); GO_0042803 (EC: IDA, PMID: 19556236); GO_0043123 (EC: IMP, PMID: 12761501); GO_0043305 (EC: IEA); GO_0043392 (EC: IEA); GO_0043433 (EC: IEA); GO_0043524 (EC: IEA); GO_0043619 (EC: ISS); GO_0043627 (EC: IEA); GO_0044281 (EC: TAS); GO_0045080 (EC: TAS, PMID: 17652371); GO_0045765 (EC: TAS, PMID: 17652371); GO_0045766 (EC: IEA); GO_0045909 (EC: IC, PMID: 17915953); GO_0046872 (EC: IEA); GO_0048661 (EC: IDA, PMID: 17600318); GO_0048662 (EC: IDA, PMID: 17600318); GO_0051090 (EC: ISS); GO_0051260 (EC: IDA, PMID: 19556236); GO_0055072 (EC: IDA, PMID: 17915953); GO_0055072 (EC: IMP, PMID: 9884342); GO_0055085 (EC: TAS); GO_0071243 (EC: IEA); GO_0071276 (EC: IEA); GO_0071456 (EC: IEP, PMID: 12511571); GO_1902042 (EC: IMP, PMID: 18202225) PMID: 2537723; 2911585; 3345742; 7778849; 8034330; 8146161; 8650873; 9884342; 9890653; 10082382; 10467099; 10591208; 10631150; 10952020; 11385506; 11718398; 11727267; 11786534; 11820797; 11829463; 11849436; 11986386; 12086318; 12091240; 12099373; 12117910; 12118938; 12130498; 12133007; 12136229; 12151344; 12153964; 12182912; 12202863; 12207883; 12222997; 12239590; 12376298; 12376363; 12376366; 12377749; 12379283; 12396617; 12397597; 12431619; 12433915; 12469218; 12477932; 12480749; 12493432; 12500973; 12511571; 12566526; 12579334; 12585963; 12626517; 12649161; 12679469; 12690112; 12709566; 12709568; 12709569; 12709590; 12709592; 12716475; 12730098; 12736395; 12761501; 12777398; 12783778; 12805077; 12810075; 12832044; 12842469; 12865654; 12872043; 12891549; 12909459; 12927812; 12927819; 12933701; 12941774; 12947311; 12969148; 13678532; 14521259; 14523007; 14525760; 14529548; 14587309; 14615405; 14635185; 14647439; 14660632; 14683741; 14691581; 14715242; 14726403; 14733911; 14981149; 14988408; 14992466; 15004156; 15024026; 15028349; 15049686; 15064108; 15084931; 15140586; 15161530; 15166181; 15184199; 15233805; 15284058; 15285018; 15297453; 15316927; 15319861; 15336443; 15337692; 15342556; 15365571; 15451051; 15461802; 15465821; 15470195; 15474356; 15516695; 15519649; 15522396; 15525643; 15544924; 15547665; 15581622; 15611319; 15618017; 15629867; 15652505; 15661856; 15688187; 15690204; 15741166; 15763346; 15797262; 15797755; 15805230; 15817713; 15833736; 15834587; 15849554; 15875813; 15878918; 15885363; 15897578; 15899048; 15964514; 16020495; 16100019; 16117883; 16123320; 16154535; 16181102; 16189191; 16210136; 16232329; 16234431; 16249618; 16271489; 16309585; 16309586; 16309588; 16313248; 16319139; 16374439; 16387424; 16399210; 16455537; 16462769; 16474202; 16485041; 16495813; 16530877; 16540907; 16545694; 16582079; 16596642; 16609364; 16620829; 16697692; 16712795; 16724942; 16771696; 16772700; 16783602; 16804400; 16840713; 16849502; 16882737; 16887359; 16923960; 16945925; 16950787; 16951197; 16971418; 16999951; 17003650; 17018578; 17018862; 17020887; 17064313; 17065227; 17079780; 17081983; 17095719; 17203192; 17204476; 17211576; 17216339; 17219054; 17229906; 17244614; 17254481; 17277740; 17295091; 17389623; 17391133; 17400606; 17413033; 17452746; 17467999; 17511591; 17520317; 17526019; 17526500; 17531161; 17541213; 17558910; 17567933; 17600318; 17601350; 17603281; 17620093; 17652371; 17657593; 17667816; 17721824; 17726138; 17823375; 17853070; 17873285; 17883332; 17886034; 17896171; 17915953; 17919491; 17919492; 17927807; 17953374; 17964723; 17971338; 17991645; 18007994; 18042465; 18045827; 18048809; 18050210; 18077487; 18093274; 18174022; 18195184; 18200441; 18201862; 18202225; 18205746; 18216050; 18234118; 18261117; 18272347; 18274635; 18275848; 18289072; 18307065; 18312299; 18332044; 18344023; 18381758; 18390757; 18404535; 18443197; 18459998; 18460015; 18461097; 18483307; 18502573; 18508827; 18515325; 18524839; 18544348; 18550526; 18560362; 18566988; 18576916; 18582925; 18586007; 18587252; 18596041; 18597895; 18620357; 18640487; 18651163; 18665050; 18689604; 18692581; 18757839; 18769149; 18774956; 18786476; 18787101; 18799519; 18804049; 18811919; 18841019; 18845641; 18923065; 18930811; 18957281; 18975324; 18977241; 18981090; 18983509; 19056482; 19120903; 19122175; 19129475; 19133325; 19165391; 19194559; 19236506; 19238116; 19243019; 19243105; 19246912; 19250338; 19255063; 19255829; 19282863; 19289500; 19303319; 19322201; 19325051; 19336475; 19360326; 19371606; 19389234; 19399816; 19422386; 19428335; 19445907; 19457084; 19457866; 19475336; 19484149; 19487598; 19508729; 19522732; 19526221; 19526463; 19536150; 19548360; 19556236; 19578796; 19586801; 19587144; 19590927; 19604147; 19625608; 19669099; 19676145; 19696228; 19777608; 19785642; 19797297; 19808663; 19808972; 19822148; 19850937; 19853072; 19874887; 19879747; 19884647; 19886851; 19895178; 19903700; 19903769; 19910578; 19913121; 19924377; 19925812; 19965783; 20013271; 20020468; 20021945; 20039940; 20049130; 20064636; 20110814; 20121710; 20127796; 20155807; 20170613; 20175935; 20188821; 20190330; 20193368; 20194081; 20223113; 20229611; 20232486; 20299368; 20345481; 20345975; 20346360; 20351094; 20386498; 20395442; 20404253; 20416077; 20430037; 20446774; 20482362; 20485444; 20504881; 20508205; 20509889; 20518850; 20526373; 20580464; 20585394; 20587610; 20597111; 20599261; 20628086; 20633528; 20667089; 20682519; 20689807; 20705711; 20706680; 20708634; 20733275; 20796278; 20811623; 20832528; 20838751; 20846452; 20868356; 20869265; 20934533; 20938987; 21037234; 21044950; 21079975; 21080099; 21081499; 21091076; 21102410; 21113640; 21136273; 21144518; 21148661; 21157922; 21172416; 21174817; 21191307; 21198350; 21206978; 21211285; 21216973; 21233593; 21236443; 21275653; 21296438; 21307400; 21321939; 21354100; 21366594; 21389316; 21412259; 21425334; 21426408; 21454555; 21495030; 21497776; 21502755; 21506927; 21518986; 21525764; 21531452; 21545264; 21552291; 21555518; 21556890; 21576421; 21598088; 21620964; 21646819; 21647550; 21725851; 21729576; 21737788; 21741353; 21742584; 21756955; 21765894; 21781496; 21808062; 21827279; 21833623; 21861350; 21868703; 21889036; 21898994; 21902835; 21906983; 21911884; 21911919; 21945498; 21963094; 21982894; 21987660; 21988832; 21992109; 22048453; 22078849; 22088544; 22095074; 22123460; 22137262; 22138245; 22142473; 22147556; 22155307; 22158875; 22200625; 22203790; 22212955; 22264017; 22271370; 22276118; 22290142; 22302482; 22323644; 22330859; 22338608; 22418244; 22427825; 22438807; 22461696; 22490514; 22503972; 22541814; 22542718; 22545110; 22549002; 22559824; 22573121; 22578468; 22578957; 22579918; 22580187; 22583702; 22587389; 22594519; 22613607; 22630328; 22666428; 22670665; 22682876; 22689053; 22698995; 22750196; 22776971; 22842631; 22843690; 22849380; 22875919; 22879597; 22881289; 22901690; 22939811; 22945906; 22959128; 22966170; 22989377; 23010497; 23046979; 23051580; 23052192; 23055342; 23074199; 23087099; 23090292; 23092328; 23103292; 23114386; 23123430; 23139759; 23150184; 23158494; 23221079; 23226098; 23238643; 23251661; 23255485; 23288142; 23293173; 23324179; 23345623; 23403148; 23403272; 23406266; 23406650; 23412940; 23423194; 23430116; 23437133; 23454680; 23521418; 23526997; 23536693; 23569422; 23571756; 23580430; 23583371; 23602216; 23606537; 23615401; 23617628; 23660665; 23665328; 23671274; 23714423; 23720344; 23725037; 23737527; 23792437; 23840483; 24038461; 24053646; 24109237; 24211270; 24239896 heme oxygenase (decycling) 1 Ensembl:ENSG00000100292 HGNC:5013 HPRD:00782 MIM:141250 Vega:OTTHUMG00000150960 HMOX1 Bin Zhao, Yue Liu, Oliver He HSP70-1B HSP70-2 WEB: http://www.ncbi.nlm.nih.gov/gene HSPA1B heat shock 70kDa protein 1B 3304 DAAP-21F2.7 6p21.3 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0001618 (EC: IEA); GO_0003725 (EC: IDA); GO_0005515 (EC: IPI, PMID: 12853476); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA, PMID: 10205060); GO_0005737 (EC: IDA, PMID: 10859165); GO_0005737 (EC: TAS, PMID: 16130169); GO_0005739 (EC: TAS, PMID: 16130169); GO_0005783 (EC: TAS, PMID: 16130169); GO_0005829 (EC: TAS); GO_0006402 (EC: IDA, PMID: 10205060); GO_0006986 (EC: IDA, PMID: 10859165); GO_0008180 (EC: IDA, Qualifier: colocalizes_with, PMID: 18850735); GO_0008285 (EC: IMP, PMID: 9553041); GO_0010467 (EC: TAS); GO_0016070 (EC: TAS); GO_0016071 (EC: TAS); GO_0016234 (EC: IDA, PMID: 15603737); GO_0016235 (EC: IDA, PMID: 15885686); GO_0016607 (EC: IDA, PMID: 9553041); GO_0030308 (EC: IMP, PMID: 9553041); GO_0030529 (EC: IDA, PMID: 17289661); GO_0031625 (EC: IPI, PMID: 15603737); GO_0042026 (EC: IDA, PMID: 15603737); GO_0043066 (EC: IMP, PMID: 17167422); GO_0043066 (EC: TAS, PMID: 16130169); GO_0044183 (EC: IDA, PMID: 15603737); GO_0044822 (EC: IDA); GO_0045648 (EC: IMP, PMID: 17167422); GO_0047485 (EC: IPI, PMID: 9553041); GO_0048471 (EC: IDA, PMID: 10205060); GO_0051082 (EC: TAS, PMID: 16130169); GO_0070062 (EC: IDA, PMID: 19199708); GO_0072562 (EC: IDA); GO_0090084 (EC: IDA, PMID: 15603737); GO_2001240 (EC: IMP, PMID: 17167422) PMID: 1478667; 1700760; 2538825; 2858050; 2880793; 3019832; 3470951; 3786141; 3931075; 7906708; 9553041; 10205060; 10216320; 10617616; 10859165; 10964507; 11231577; 11533664; 11696222; 11730740; 11779758; 11864979; 11932435; 11971973; 12008944; 12082592; 12207910; 12391142; 12411538; 12477932; 12490434; 12544996; 12691826; 12703993; 12730033; 12832005; 12853476; 12967056; 14506234; 14574404; 14605873; 14656967; 15165109; 15223990; 15232679; 15236755; 15324660; 15489334; 15492215; 15603737; 15671022; 15714129; 15748471; 15885686; 15963462; 15963589; 15992611; 16130169; 16165702; 16169070; 16202503; 16236267; 16275660; 16333988; 16344560; 16441767; 16525348; 16713569; 16804002; 16953332; 16964243; 17081983; 17158748; 17167422; 17289661; 17301649; 17311111; 17314700; 17342744; 17364813; 17428599; 17532782; 17558451; 17582394; 17620599; 17940904; 18191480; 18299791; 18344806; 18478330; 18518860; 18529014; 18551993; 18580445; 18759004; 18813331; 18818748; 18822209; 18844219; 18850735; 18975920; 18987644; 19019335; 19046306; 19085089; 19199708; 19275587; 19287380; 19299493; 19322201; 19335985; 19351530; 19380743; 19439993; 19527514; 19596686; 19626584; 19643584; 19661373; 19731315; 19738201; 19754858; 19759913; 19840767; 19851445; 20012387; 20043082; 20140262; 20207250; 20388090; 20498198; 20568452; 20587610; 20639865; 20692469; 20704535; 20714140; 20876613; 20972266; 21139048; 21145461; 21360678; 21373891; 21471543; 21487019; 21693764; 21738007; 21738476; 21763498; 21890473; 21906983; 21963094; 21970979; 21987572; 21988832; 22037874; 22053931; 22160620; 22268729; 22323290; 22468780; 22505724; 22623428; 22797398; 22834788; 22883735; 22922572; 23000965; 23065205; 23182705; 23184937; 23246001; 23330093; 23349634; 23425104; 23455922; 23490384; 23798571; 23862649; 23874968; 23885119; 24457600 heat shock 70kDa protein 1B Ensembl:ENSG00000204388 HGNC:5233 HPRD:06784 MIM:603012 Vega:OTTHUMG00000031202 HSPA1B Bin Zhao, Yue Liu, Oliver He BIP GRP78 HEL-S-89n MIF2 WEB: http://www.ncbi.nlm.nih.gov/gene HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 3309 9q33.3 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0002576 (EC: TAS); GO_0005509 (EC: TAS, PMID: 16130169); GO_0005515 (EC: IPI, PMID: 11907036); GO_0005524 (EC: IEA); GO_0005634 (EC: IMP, PMID: 11943137); GO_0005783 (EC: IDA, PMID: 16223484); GO_0005783 (EC: IMP, PMID: 11943137); GO_0005783 (EC: TAS, PMID: 16130169); GO_0005788 (EC: TAS); GO_0005789 (EC: TAS); GO_0005793 (EC: IDA, PMID: 15308636); GO_0006200 (EC: ISS); GO_0006983 (EC: IEA); GO_0006987 (EC: TAS); GO_0007596 (EC: TAS); GO_0008180 (EC: IDA, Qualifier: colocalizes_with, PMID: 18850735); GO_0009986 (EC: IEA); GO_0016887 (EC: ISS); GO_0019904 (EC: IPI, PMID: 12411443); GO_0021589 (EC: IEA); GO_0021680 (EC: IEA); GO_0021762 (EC: IEP); GO_0030168 (EC: TAS); GO_0030176 (EC: IDA, PMID: 11181571); GO_0030335 (EC: IMP); GO_0030433 (EC: TAS, PMID: 19816510); GO_0030496 (EC: IDA, PMID: 15166316); GO_0030512 (EC: IEA); GO_0030968 (EC: TAS, PMID: 19816510); GO_0031398 (EC: IEA); GO_0031625 (EC: IPI, PMID: 8666824); GO_0034663 (EC: IDA, PMID: 18400946); GO_0035437 (EC: IMP); GO_0042149 (EC: IDA, PMID: 10085239); GO_0042470 (EC: IEA); GO_0043022 (EC: IEA); GO_0043066 (EC: IMP, PMID: 10760948); GO_0043066 (EC: TAS, PMID: 16130169); GO_0044267 (EC: TAS); GO_0051082 (EC: TAS, PMID: 16130169); GO_0051087 (EC: TAS, PMID: 19816510); GO_0051787 (EC: IDA, PMID: 18400946); GO_0060904 (EC: TAS, PMID: 19816510); GO_0070062 (EC: IDA, PMID: 19056867); GO_0071236 (EC: IEA); GO_0071353 (EC: IEA) PMID: 1480470; 1602151; 1649196; 1900540; 2294010; 2840249; 3087629; 3122216; 7724523; 7878056; 7906708; 7957306; 8020977; 8666824; 9006956; 9150946; 9150948; 9305856; 9409741; 9492298; 9885241; 10049727; 10085239; 10197448; 10397760; 10461883; 10514465; 10588643; 10617616; 10708769; 10760948; 10777498; 10887119; 10906332; 10964507; 10964928; 10970892; 11013075; 11160188; 11162507; 11162551; 11181571; 11294872; 11476899; 11719466; 11751874; 11752154; 11765911; 11790298; 11907036; 11932435; 11943137; 12076252; 12097557; 12194978; 12356756; 12359150; 12383251; 12397072; 12411443; 12471035; 12475965; 12477932; 12480769; 12493773; 12514190; 12516782; 12552023; 12621026; 12637535; 12643545; 12665508; 12713871; 12832005; 12840015; 15009096; 15077298; 15146195; 15150263; 15166316; 15280358; 15308636; 15324660; 15456888; 15489334; 15514946; 15525676; 15618547; 15635413; 15657421; 15664986; 15778089; 15817150; 15899857; 15908432; 15949590; 15952740; 16027165; 16051665; 16130169; 16168956; 16169070; 16182273; 16196087; 16212417; 16223484; 16236267; 16257961; 16282978; 16329989; 16344560; 16400691; 16428306; 16472112; 16488447; 16497268; 16522924; 16543232; 16731524; 16912156; 16912197; 17002502; 17062670; 17081065; 17139257; 17184779; 17215244; 17220478; 17337485; 17380188; 17431395; 17601350; 17620599; 17640713; 17643375; 17670764; 17683050; 17721549; 17725712; 17728248; 17765891; 17805346; 17848573; 17906960; 17931354; 17932454; 17936241; 17942541; 17979178; 17991893; 18022401; 18064632; 18083346; 18192872; 18264092; 18268478; 18278507; 18331622; 18343577; 18400946; 18403493; 18411300; 18457437; 18482745; 18502753; 18556570; 18654987; 18708056; 18708359; 18720263; 18757373; 18776923; 18781276; 18781797; 18790759; 18840615; 18842681; 18850735; 18977241; 19014922; 19017364; 19056867; 19097122; 19103594; 19107326; 19128512; 19135240; 19151922; 19164805; 19165527; 19167051; 19188365; 19193609; 19212831; 19228285; 19236758; 19275587; 19287380; 19296942; 19309398; 19343720; 19380743; 19386345; 19411306; 19421146; 19470730; 19471022; 19482905; 19533686; 19546472; 19596686; 19616278; 19626590; 19632185; 19659607; 19671925; 19674193; 19713465; 19718440; 19722195; 19738201; 19741001; 19765186; 19776128; 19786088; 19815544; 19815549; 19816510; 19823030; 19838160; 19838163; 19842229; 19845896; 19850743; 19875381; 19950238; 20017148; 20020773; 20028516; 20072656; 20082722; 20085233; 20145413; 20171186; 20176102; 20204278; 20208072; 20213805; 20360535; 20371724; 20457808; 20473863; 20473970; 20484513; 20492754; 20497865; 20506407; 20508642; 20525207; 20605795; 20628775; 20651985; 20664690; 20672702; 20720212; 20735358; 20739513; 20936779; 20979610; 21056970; 21080038; 21081666; 21112319; 21118962; 21137052; 21139048; 21145461; 21156321; 21189163; 21199322; 21203488; 21221131; 21252943; 21319273; 21343306; 21374734; 21382870; 21389343; 21418596; 21467168; 21472681; 21479362; 21503958; 21516372; 21565611; 21597391; 21622563; 21642380; 21673190; 21738476; 21745816; 21763498; 21779363; 21800051; 21825151; 21840908; 21853274; 21890413; 21890473; 21903092; 21906983; 21940774; 21947079; 21947694; 21963094; 21965664; 21987572; 21988832; 22004425; 22076227; 22079093; 22146569; 22178446; 22215138; 22234250; 22268729; 22297694; 22306319; 22425662; 22427667; 22430489; 22438978; 22446326; 22460328; 22472071; 22495374; 22505724; 22527697; 22528773; 22536838; 22543280; 22546345; 22564965; 22581315; 22613557; 22627132; 22689054; 22735594; 22751133; 22752300; 22796945; 22801219; 22810585; 22851173; 22855534; 22863883; 22889453; 22912664; 22939629; 22945507; 22963397; 22996014; 23000965; 23056589; 23085757; 23089287; 23097496; 23123197; 23161089; 23182705; 23184937; 23200913; 23220234; 23233672; 23246001; 23277564; 23280503; 23314748; 23318453; 23322163; 23349634; 23363602; 23378021; 23383273; 23398456; 23402259; 23402331; 23416888; 23428871; 23438482; 23455922; 23456958; 23457489; 23470966; 23485528; 23544152; 23569248; 23575540; 23578665; 23703321; 23721263; 23759331; 23760505; 23798571; 23818965; 23862649; 23922175; 23956138; 24030972; 24080088; 24113185; 24113381; 24155957; 24239288; 24244333; 24457600 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Ensembl:ENSG00000044574 HGNC:5238 HPRD:00682 MIM:138120 Vega:OTTHUMG00000020672 HSPA5 Bin Zhao, Yue Liu, Oliver He CPN60 GROEL HLD4 HSP-60 HSP60 HSP65 HuCHA60 SPG13 WEB: http://www.ncbi.nlm.nih.gov/gene HSPD1 heat shock 60kDa protein 1 (chaperonin) 3329 2q33.1 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0001530 (EC: IDA, PMID: 17164250); GO_0002039 (EC: IPI, PMID: 18086682); GO_0002368 (EC: IDA, PMID: 16148103); GO_0002755 (EC: IDA, PMID: 16148103); GO_0002842 (EC: IDA, PMID: 10663613); GO_0003688 (EC: ISS); GO_0003697 (EC: ISS); GO_0003725 (EC: IDA); GO_0005515 (EC: IPI, PMID: 17823127); GO_0005524 (EC: IEA); GO_0005615 (EC: IDA, PMID: 18229457); GO_0005737 (EC: IDA); GO_0005739 (EC: IDA); GO_0005743 (EC: ISS); GO_0005759 (EC: TAS, PMID: 17823127); GO_0005769 (EC: IDA, PMID: 11807771); GO_0005829 (EC: IDA, PMID: 17823127); GO_0005886 (EC: IEA); GO_0005905 (EC: IDA, PMID: 11807771); GO_0006200 (EC: ISS); GO_0006458 (EC: ISS); GO_0006919 (EC: IDA, PMID: 17823127); GO_0006986 (EC: IDA, PMID: 11050098); GO_0009986 (EC: IDA, PMID: 10663613); GO_0016032 (EC: IEA); GO_0016887 (EC: ISS); GO_0019907 (EC: IDA, Qualifier: colocalizes_with, PMID: 11445587); GO_0030135 (EC: IDA, PMID: 11807771); GO_0030141 (EC: ISS); GO_0032727 (EC: IDA, PMID: 17164250); GO_0032729 (EC: IDA, PMID: 17164250); GO_0032729 (EC: ISS); GO_0032733 (EC: IDA, PMID: 16148103); GO_0032735 (EC: IDA, PMID: 17164250); GO_0032755 (EC: IDA, PMID: 16148103); GO_0042026 (EC: IDA, PMID: 11050098); GO_0042100 (EC: IDA, PMID: 16148103); GO_0042110 (EC: IDA, PMID: 15371451); GO_0042113 (EC: IDA, PMID: 16148103); GO_0043032 (EC: IDA, PMID: 17164250); GO_0043065 (EC: IMP, PMID: 17823127); GO_0043066 (EC: IMP, PMID: 17823127); GO_0043234 (EC: IDA); GO_0044822 (EC: IDA); GO_0046696 (EC: IDA, PMID: 17164250); GO_0048291 (EC: IDA, PMID: 16148103); GO_0050821 (EC: IMP, PMID: 18086682); GO_0050821 (EC: ISS); GO_0050870 (EC: IDA, PMID: 16148103); GO_0050870 (EC: ISS); GO_0051082 (EC: IC, PMID: 11050098); GO_0051082 (EC: ISS); GO_0051087 (EC: IPI, PMID: 10205158); GO_0051131 (EC: ISS); GO_0051604 (EC: ISS); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1286669; 1347942; 1516759; 1602151; 1972619; 1980192; 2079031; 2568584; 2907406; 7518175; 7895732; 7907543; 7911805; 8559246; 8671282; 8676499; 8678928; 8689794; 8845058; 8882520; 8976559; 8979276; 9051195; 9150946; 9150948; 9243807; 9724719; 9890926; 10205158; 10205159; 10231001; 10231004; 10326659; 10382997; 10449265; 10467106; 10499815; 10508170; 10632533; 10663613; 10677329; 10731000; 10811634; 10960671; 11050098; 11144526; 11145923; 11230124; 11337467; 11445587; 11488911; 11591125; 11689615; 11777905; 11790298; 11807771; 11860186; 11862386; 11888933; 11898127; 11932435; 12070120; 12105158; 12195124; 12215374; 12218165; 12234937; 12387818; 12406306; 12461076; 12477932; 12483302; 12493773; 12515899; 12552239; 12594256; 12611882; 12665801; 12684064; 12686536; 12768547; 12813381; 12869561; 12890148; 12942564; 12965262; 14500649; 14634555; 14717702; 14968112; 15047060; 15242332; 15249499; 15251360; 15324660; 15371451; 15489334; 15529360; 15546885; 15590416; 15592455; 15618521; 15635413; 15661886; 15763499; 15784682; 15875659; 15879154; 15952740; 15957980; 16009940; 16075307; 16116071; 16130169; 16148103; 16159877; 16196087; 16212417; 16215457; 16236267; 16253146; 16254226; 16320351; 16335966; 16482509; 16705742; 16723087; 16767222; 16843693; 16887805; 16964243; 16978514; 17072495; 17075864; 17110338; 17148442; 17164250; 17174952; 17202307; 17206383; 17314511; 17317785; 17420921; 17420924; 17540176; 17553457; 17584768; 17588138; 17643375; 17670764; 17675567; 17681147; 17823127; 17915559; 17925998; 18029348; 18086682; 18229457; 18240224; 18256040; 18319262; 18320357; 18322079; 18372523; 18399535; 18400758; 18457437; 18458233; 18571143; 18685789; 18692161; 18781797; 18790094; 18815895; 18987317; 19004824; 19008717; 19022255; 19056867; 19106391; 19109096; 19110265; 19132982; 19156129; 19205928; 19207939; 19210880; 19261350; 19264393; 19306954; 19336475; 19338310; 19343720; 19346294; 19369584; 19380743; 19386281; 19423133; 19471022; 19475432; 19565483; 19568603; 19576649; 19635199; 19706612; 19738201; 19764566; 19765186; 19875724; 19913588; 20082317; 20169074; 20186120; 20193073; 20351780; 20362058; 20471030; 20639865; 20686813; 20694586; 20708221; 20806039; 20877624; 20936779; 20947377; 20953657; 20972266; 20978188; 21081666; 21139048; 21145461; 21319273; 21361146; 21497776; 21642380; 21671464; 21717087; 21726808; 21748374; 21832049; 21840382; 21853274; 21890473; 21906983; 21963094; 21987572; 21988832; 22012253; 22079093; 22140545; 22178446; 22258649; 22268729; 22304920; 22315307; 22319627; 22492505; 22505724; 22575645; 22623428; 22751105; 22753410; 22810585; 22847064; 22848686; 22863883; 22882677; 22901435; 22904065; 22931585; 22933632; 22939629; 22944692; 23000965; 23028910; 23077236; 23184937; 23192457; 23246001; 23276948; 23349634; 23357787; 23388486; 23398456; 23424650; 23429486; 23438482; 23455922; 23466130; 23798571; 23807299; 23862649; 24084737; 24113772; 24123003; 24244333; 24250222; 24457600 heat shock 60kDa protein 1 (chaperonin) Ensembl:ENSG00000144381 HGNC:5261 HPRD:00318 MIM:118190 Vega:OTTHUMG00000154463 HSPD1 Bin Zhao, Yue Liu, Oliver He BB2 CD54 P3.58 WEB: http://www.ncbi.nlm.nih.gov/gene ICAM1 intercellular adhesion molecule 1 3383 19p13.3-p13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0001541 (EC: IEA); GO_0001618 (EC: IEA); GO_0001772 (EC: IEA); GO_0001910 (EC: TAS, PMID: 16038038); GO_0001975 (EC: IEA); GO_0002291 (EC: IMP, PMID: 2477710); GO_0002457 (EC: IEA); GO_0002693 (EC: IMP, PMID: 12902516); GO_0004872 (EC: TAS, PMID: 2538243); GO_0004888 (EC: TAS, PMID: 2538243); GO_0005178 (EC: IPI, PMID: 1448173); GO_0005515 (EC: IPI, PMID: 12716892); GO_0005615 (EC: IDA, PMID: 9290466); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 2538243); GO_0007155 (EC: IDA, PMID: 16809613); GO_0007157 (EC: TAS, PMID: 2477710); GO_0007159 (EC: IMP, PMID: 2477710); GO_0007569 (EC: IEA); GO_0008360 (EC: IEA); GO_0009897 (EC: IEA); GO_0010212 (EC: IEA); GO_0010477 (EC: IEA); GO_0014070 (EC: IEA); GO_0019221 (EC: TAS); GO_0022614 (EC: IEP, PMID: 12082081); GO_0030155 (EC: IEA); GO_0030198 (EC: TAS); GO_0030838 (EC: IEA); GO_0031669 (EC: IEA); GO_0032321 (EC: IEA); GO_0033627 (EC: IEA); GO_0034698 (EC: IEA); GO_0042493 (EC: IEA); GO_0043200 (EC: IEA); GO_0045429 (EC: IEA); GO_0045471 (EC: IEA); GO_0045907 (EC: IEA); GO_0046688 (EC: IEA); GO_0046813 (EC: IDA, PMID: 2538243); GO_0050731 (EC: IEA); GO_0050776 (EC: TAS); GO_0050900 (EC: IEP, PMID: 12082081); GO_0051092 (EC: IEA); GO_0051856 (EC: IDA, PMID: 2538243); GO_0051926 (EC: IEA); GO_0060333 (EC: TAS); GO_0061028 (EC: IGI); GO_0070062 (EC: IDA, PMID: 19056867); GO_0071222 (EC: IEA); GO_0071312 (EC: IEA); GO_0071333 (EC: IEA); GO_0071347 (EC: IEA); GO_0071356 (EC: IEA); GO_0071456 (EC: IEA) PMID: 1361527; 1374132; 1448173; 1625472; 1677359; 1680025; 1680698; 1680919; 1683616; 1683685; 1705751; 1712819; 1722744; 1976256; 1983003; 2453850; 2477710; 2538243; 2544880; 2566624; 3257922; 3340213; 3349522; 3871395; 7525451; 7642561; 7794538; 7822297; 7904170; 7913356; 7917519; 8086129; 8095960; 8432525; 8450224; 8557254; 8558011; 8568270; 8821031; 9259284; 9269771; 9290466; 9488691; 9539702; 9539703; 9705328; 9792375; 9865497; 10198043; 10352278; 10391210; 10477700; 10493852; 10562537; 10602408; 10699175; 10985244; 11072593; 11073102; 11250042; 11279101; 11354638; 11361181; 11409120; 11441079; 11469468; 11508575; 11517385; 11716965; 11726228; 11751911; 11776680; 11786177; 11817671; 11831440; 11831864; 11837795; 11838958; 11847011; 11857637; 11877286; 11881155; 11882338; 11893710; 11896203; 11911111; 11914659; 11922836; 11922919; 11929876; 11935152; 11936473; 11953106; 11956618; 11963839; 11983194; 11983205; 12011765; 12020443; 12027924; 12039084; 12082081; 12082592; 12086338; 12095649; 12097408; 12097820; 12117984; 12127369; 12147222; 12172318; 12172576; 12175089; 12181421; 12192299; 12207164; 12208882; 12220988; 12368450; 12370391; 12391099; 12393699; 12402194; 12477764; 12477932; 12480084; 12496412; 12498973; 12506144; 12509902; 12524171; 12526797; 12529420; 12530121; 12533701; 12590979; 12595908; 12600815; 12624779; 12637697; 12645577; 12660163; 12660796; 12673844; 12714373; 12714566; 12715098; 12716892; 12745437; 12768436; 12775419; 12783117; 12783123; 12788528; 12798307; 12808331; 12829919; 12853962; 12871600; 12902516; 12915579; 12918698; 12939654; 12940514; 12946329; 12954625; 12958678; 14504278; 14533030; 14534081; 14550782; 14551606; 14557478; 14572449; 14572618; 14581566; 14605444; 14609725; 14634129; 14643123; 14691297; 14695458; 14714557; 14722298; 14734737; 14737745; 14741380; 14742996; 14763917; 14763979; 14975197; 14984317; 14993495; 15009098; 15013836; 15048650; 15057477; 15059493; 15080580; 15081401; 15094060; 15123348; 15140794; 15169768; 15183063; 15208262; 15210758; 15212674; 15221034; 15246972; 15272865; 15279951; 15290909; 15294853; 15304054; 15308783; 15313174; 15331359; 15331736; 15334673; 15334773; 15342556; 15353596; 15361125; 15379751; 15387368; 15389590; 15448102; 15479832; 15489334; 15545280; 15548573; 15550998; 15560890; 15572059; 15583842; 15593054; 15607204; 15611342; 15650392; 15654951; 15665526; 15666579; 15682683; 15696921; 15713910; 15724813; 15736117; 15756053; 15760456; 15774488; 15800027; 15817812; 15829968; 15831709; 15853902; 15854776; 15864742; 15866119; 15883744; 15886114; 15896355; 15914533; 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17237434; 17255534; 17278022; 17292586; 17309130; 17311092; 17328035; 17334226; 17337890; 17340048; 17361014; 17389327; 17390085; 17397790; 17429072; 17476188; 17497038; 17517105; 17521325; 17531998; 17551301; 17560459; 17564956; 17583675; 17591777; 17591781; 17593226; 17598660; 17607549; 17609265; 17640650; 17657162; 17677000; 17703412; 17704297; 17706337; 17706953; 17708604; 17710630; 17785844; 17786132; 17803991; 17868277; 17873320; 17875742; 17885215; 17891599; 17908278; 17913807; 17942534; 17943642; 17954174; 17956423; 17962597; 17962718; 17963163; 17969524; 17974148; 17977219; 17982228; 17990298; 18028430; 18029348; 18045607; 18057581; 18160848; 18164036; 18186794; 18197885; 18199704; 18200516; 18212564; 18227124; 18230913; 18231758; 18233990; 18243419; 18256065; 18260262; 18284603; 18295170; 18297282; 18322230; 18361930; 18362147; 18363879; 18392953; 18401716; 18403635; 18415799; 18420209; 18422166; 18440309; 18446055; 18454303; 18473826; 18474291; 18486623; 18504269; 18505543; 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19420105; 19423540; 19429776; 19434537; 19449444; 19452711; 19479237; 19483084; 19494354; 19497039; 19500134; 19501575; 19520829; 19524015; 19524923; 19526283; 19540498; 19548631; 19554506; 19559392; 19564823; 19567179; 19573080; 19578796; 19587009; 19587357; 19597294; 19615354; 19625176; 19661147; 19691982; 19692168; 19701669; 19701972; 19710135; 19714575; 19717975; 19724852; 19729601; 19747913; 19764564; 19773279; 19822019; 19825506; 19882756; 19896127; 19898481; 19906207; 19912576; 19913121; 19914206; 19917355; 19922364; 19935876; 19948975; 19949084; 19954409; 20004360; 20056088; 20056178; 20056442; 20083573; 20107176; 20110463; 20118004; 20137698; 20139322; 20151764; 20158572; 20160446; 20164172; 20167578; 20184510; 20187292; 20191078; 20193033; 20217214; 20219985; 20237496; 20304924; 20331378; 20360068; 20360547; 20362293; 20389059; 20405289; 20406964; 20409464; 20409465; 20416077; 20422421; 20430730; 20432452; 20438785; 20445114; 20459645; 20473930; 20485444; 20494378; 20503287; 20508517; 20510872; 20511548; 20529672; 20536507; 20552237; 20566577; 20568250; 20570633; 20574001; 20585554; 20587315; 20588308; 20596527; 20602615; 20603037; 20628086; 20647315; 20662732; 20665551; 20680966; 20681010; 20685094; 20712868; 20714774; 20725844; 20819778; 20837907; 20864106; 20880684; 20890395; 20929696; 20935502; 20940515; 20951945; 21037509; 21039424; 21067572; 21078912; 21102463; 21159528; 21162967; 21171946; 21172429; 21173732; 21183689; 21183871; 21236259; 21270398; 21286024; 21287514; 21328467; 21344487; 21390226; 21391218; 21392767; 21474934; 21487066; 21520070; 21533024; 21536333; 21536861; 21540444; 21542832; 21551251; 21571262; 21590495; 21594636; 21610569; 21628959; 21635548; 21641584; 21658317; 21668410; 21680714; 21717173; 21724992; 21725974; 21798038; 21804483; 21808112; 21816944; 21828047; 21840991; 21843619; 21850260; 21860531; 21871109; 21877251; 21890178; 21895545; 21906983; 21963094; 21972703; 21980389; 21987404; 21988832; 22001052; 22010135; 22015609; 22023772; 22045868; 22059356; 22103402; 22119941; 22183741; 22198381; 22203486; 22209338; 22226621; 22226679; 22234743; 22248682; 22294843; 22324942; 22345292; 22349390; 22378734; 22378736; 22396143; 22404936; 22433250; 22448134; 22463128; 22489699; 22496445; 22497223; 22523428; 22523875; 22525368; 22533155; 22541082; 22552687; 22552879; 22558273; 22560286; 22562265; 22588952; 22591361; 22593994; 22609477; 22609871; 22619799; 22644863; 22646485; 22648254; 22685016; 22697794; 22705151; 22706247; 22707713; 22717098; 22742445; 22763042; 22763828; 22780972; 22782142; 22804504; 22815910; 22905988; 22908191; 22909232; 22972240; 22976263; 22990627; 23039186; 23042271; 23053371; 23053969; 23057424; 23089253; 23095194; 23098564; 23111892; 23128233; 23144497; 23162921; 23178493; 23209327; 23227846; 23232649; 23238746; 23264465; 23297413; 23349778; 23356193; 23364881; 23376231; 23376424; 23383040; 23417849; 23438482; 23438786; 23457623; 23463506; 23493781; 23502765; 23554905; 23558934; 23561648; 23576799; 23581432; 23609612; 23616566; 23625043; 23663325; 23671702; 23677452; 23685129; 23690481; 23726130; 23792525; 23844251; 23906304; 23922493; 23935498; 24077340; 24157824; 24273934; 24282904 intercellular adhesion molecule 1 Ensembl:ENSG00000090339 HGNC:5344 HPRD:00996 MIM:147840 Vega:OTTHUMG00000180403 ICAM1 Bin Zhao, Yue Liu, Oliver He INSULYSIN WEB: http://www.ncbi.nlm.nih.gov/gene IDE insulin-degrading enzyme 3416 RP11-366I13.1 10q23-q25 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0001540 (EC: IEA); GO_0001948 (EC: IPI, PMID: 17055432); GO_0004222 (EC: IDA, PMID: 17051221); GO_0005102 (EC: IPI); GO_0005515 (EC: IPI, PMID: 17715127); GO_0005524 (EC: IDA, PMID: 17613531); GO_0005615 (EC: IDA, PMID: 9830016); GO_0005634 (EC: IDA, PMID: 15285718); GO_0005634 (EC: IDA, Qualifier: NOT, PMID: 18226493); GO_0005737 (EC: IDA, PMID: 18226493); GO_0005739 (EC: IDA, PMID: 15285718); GO_0005777 (EC: IDA, PMID: 9231799); GO_0005782 (EC: IEA); GO_0005829 (EC: IDA, PMID: 15285718); GO_0005886 (EC: IEA); GO_0006508 (EC: IDA); GO_0008270 (EC: IDA, PMID: 17613531); GO_0008286 (EC: NAS, PMID: 3059494); GO_0008340 (EC: IDA, PMID: 18448515); GO_0009986 (EC: IDA, PMID: 17055432); GO_0010815 (EC: IDA, PMID: 17613531); GO_0010992 (EC: IDA); GO_0016032 (EC: IEA); GO_0016887 (EC: IEA); GO_0031597 (EC: IEA); GO_0031626 (EC: IEA); GO_0032461 (EC: IDA, PMID: 9830016); GO_0042277 (EC: IPI); GO_0042447 (EC: IEA); GO_0042803 (EC: IPI, PMID: 17613531); GO_0043130 (EC: IPI); GO_0043559 (EC: IDA, PMID: 17051221); GO_0043559 (EC: IPI); GO_0045861 (EC: IEA); GO_0050435 (EC: IDA, PMID: 17613531); GO_0051260 (EC: IDA, PMID: 17051221); GO_0051289 (EC: IEA); GO_0051291 (EC: IEA); GO_0051603 (EC: IDA, PMID: 9830016); GO_1901142 (EC: IDA, PMID: 18448515); GO_1901143 (EC: IDA, PMID: 9231799) PMID: 758022; 1607078; 1733942; 1743072; 2293021; 3059494; 6401723; 7731996; 8051160; 8077210; 8425612; 9070242; 9231799; 9830016; 10684867; 11145591; 11809755; 12161276; 12477932; 12507914; 12634421; 12716770; 12746301; 12765971; 12850277; 14517947; 14702039; 14755451; 14764804; 15024728; 15088150; 15181249; 15277398; 15277615; 15285718; 15489232; 15590928; 15718037; 15850385; 15858813; 15858821; 15911128; 16344560; 16380485; 16385451; 16511862; 16574064; 16675064; 16876916; 16914266; 17051221; 17055432; 17143514; 17192720; 17192785; 17244626; 17293876; 17463249; 17496198; 17579348; 17601350; 17613531; 17715127; 17804762; 17827400; 17913278; 17953957; 17964527; 17971426; 18212765; 18226493; 18411275; 18426861; 18448515; 18591388; 18618095; 18621727; 18633108; 18719881; 18783335; 18813847; 18977241; 18984664; 18986166; 18996360; 19019493; 19053027; 19082521; 19139842; 19228808; 19239107; 19321446; 19383491; 19396426; 19453261; 19592050; 19592620; 19602701; 19606063; 19622614; 19741166; 19785409; 19794065; 19808678; 19808892; 19809796; 19862325; 19864391; 19864659; 19889475; 19896952; 19913121; 19933996; 20033747; 20082125; 20098734; 20161779; 20178365; 20203524; 20360068; 20362553; 20364150; 20380468; 20384434; 20460429; 20490451; 20581827; 20628086; 20663017; 20703447; 20724036; 20816152; 20877624; 20880607; 20927120; 20971110; 21098034; 21139048; 21185309; 21232820; 21343292; 21731745; 21800051; 21873424; 21890473; 21903422; 21906983; 21963094; 21992747; 22036964; 22053931; 22107728; 22267728; 22502914; 22837378; 22863883; 23000965; 23036584; 23416320; 23525105; 23597493; 23922390; 24250222 insulin-degrading enzyme Ensembl:ENSG00000119912 HGNC:5381 HPRD:00894 MIM:146680 Vega:OTTHUMG00000018759 IDE Bin Zhao, Yue Liu, Oliver He IFG IFI WEB: http://www.ncbi.nlm.nih.gov/gene IFNG interferon, gamma 3458 12q14 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000060 (EC: IDA, PMID: 15604419); GO_0000122 (EC: ISS); GO_0001781 (EC: IEA); GO_0002026 (EC: IEA); GO_0002053 (EC: ISS); GO_0002250 (EC: IBA); GO_0002302 (EC: IEA); GO_0003340 (EC: ISS); GO_0005125 (EC: IBA); GO_0005133 (EC: IEA); GO_0005576 (EC: IDA); GO_0005576 (EC: TAS); GO_0005615 (EC: IBA); GO_0006915 (EC: IGI, PMID: 7828849); GO_0006928 (EC: TAS, PMID: 10477596); GO_0006959 (EC: IBA); GO_0007050 (EC: IDA, PMID: 16942485); GO_0007166 (EC: TAS, PMID: 10477596); GO_0009615 (EC: IDA, PMID: 16280321); GO_0009897 (EC: IEA); GO_0019221 (EC: TAS); GO_0019882 (EC: IEA); GO_0030593 (EC: IEA); GO_0030968 (EC: IEA); GO_0031642 (EC: IEA); GO_0032224 (EC: IEA); GO_0032700 (EC: IDA, PMID: 18501882); GO_0032735 (EC: IDA, PMID: 7605994); GO_0032747 (EC: IDA); GO_0032760 (EC: IEA); GO_0033141 (EC: IDA, PMID: 16280321); GO_0033141 (EC: NAS); GO_0034393 (EC: IDA, PMID: 16942485); GO_0042102 (EC: IEA); GO_0042493 (EC: IEA); GO_0042511 (EC: IDA, PMID: 15604419); GO_0042742 (EC: IEA); GO_0042832 (EC: IEA); GO_0044130 (EC: IEA); GO_0045080 (EC: IEA); GO_0045084 (EC: IEA); GO_0045348 (EC: IEA); GO_0045410 (EC: IEA); GO_0045429 (EC: IDA, PMID: 8383325); GO_0045666 (EC: IEA); GO_0045672 (EC: IDA, PMID: 16220542); GO_0045785 (EC: IEA); GO_0045944 (EC: IEA); GO_0048304 (EC: IEA); GO_0048662 (EC: IDA, PMID: 16942485); GO_0050718 (EC: IEA); GO_0050796 (EC: IDA, PMID: 8383325); GO_0051044 (EC: IDA, PMID: 18373975); GO_0051607 (EC: IEA); GO_0051712 (EC: IDA, PMID: 7544003); GO_0060333 (EC: TAS); GO_0060334 (EC: TAS); GO_0060550 (EC: IDA, PMID: 9282826); GO_0060552 (EC: IDA, PMID: 9282826); GO_0060557 (EC: IDA, PMID: 9282826); GO_0060559 (EC: IDA, PMID: 9282826); GO_0071222 (EC: IEA); GO_0071351 (EC: IEA); GO_0072308 (EC: ISS); GO_0097191 (EC: IDA, PMID: 16942485); GO_2000309 (EC: IDA, PMID: 16220542) PMID: 1400376; 1525157; 1662603; 1708818; 1902591; 1905933; 1905983; 2452186; 2504704; 2514776; 2860101; 3109913; 3139842; 6173769; 6176945; 6180322; 6305337; 6329718; 6427223; 7511078; 7523014; 7526537; 7544003; 7583919; 7587386; 7590734; 7605994; 7617032; 7673114; 7815507; 7818827; 7828849; 7904170; 7941321; 8065455; 8102828; 8188658; 8247028; 8345204; 8383325; 8537091; 8557999; 8598486; 8619916; 8631301; 8648753; 8661419; 8679287; 8706326; 8760410; 8764000; 8765022; 8769094; 8809126; 8974399; 9108403; 9225992; 9282826; 9534962; 9651359; 9658081; 9712080; 9743208; 9916748; 10358150; 10388525; 10438928; 10446807; 10477596; 10775602; 10860730; 10933622; 10986460; 11240951; 11250200; 11266927; 11266928; 11292301; 11298489; 11298547; 11315919; 11316066; 11354638; 11391238; 11404167; 11528517; 11544427; 11544434; 11700035; 11751951; 11755617; 11772518; 11774563; 11781187; 11781192; 11786536; 11796707; 11821159; 11830476; 11831440; 11841489; 11854199; 11854210; 11857052; 11857344; 11861290; 11865054; 11876761; 11900986; 11906646; 11920321; 11936954; 11943142; 11947926; 11953317; 11964313; 11966872; 11970958; 11980899; 11981433; 11984595; 11986281; 11986939; 11991675; 12006410; 12011077; 12020266; 12042661; 12047360; 12050152; 12060750; 12070781; 12084660; 12089333; 12089714; 12097398; 12102661; 12105273; 12162871; 12162874; 12165521; 12170266; 12191570; 12192641; 12203138; 12209087; 12219025; 12223098; 12223516; 12232842; 12239181; 12296868; 12358843; 12366695; 12368207; 12370350; 12370385; 12377943; 12389079; 12393446; 12394188; 12401479; 12420205; 12438348; 12438388; 12441140; 12444137; 12451269; 12471139; 12473063; 12477932; 12479817; 12486605; 12507818; 12526950; 12531694; 12531774; 12533683; 12542496; 12548511; 12552499; 12555203; 12558814; 12579348; 12581491; 12588705; 12590978; 12594832; 12595908; 12609526; 12615834; 12633940; 12645529; 12653164; 12700631; 12727482; 12727483; 12738388; 12750172; 12751024; 12754213; 12761564; 12788307; 12788577; 12794718; 12804771; 12813035; 12818128; 12819637; 12850811; 12851716; 12854077; 12890425; 12909463; 12914676; 12917425; 12928400; 12938195; 12944981; 12960156; 12965263; 12968017; 12975380; 14499500; 14511565; 14514772; 14522096; 14558082; 14566095; 14601649; 14602571; 14607827; 14607900; 14607968; 14625191; 14631168; 14661818; 14675394; 14675398; 14681912; 14688135; 14690454; 14692664; 14694183; 14698136; 14704034; 14734640; 14734771; 14753294; 14872501; 14959851; 14962095; 14969768; 14976609; 14978096; 14988089; 14992891; 14993214; 15004750; 15007355; 15018649; 15019280; 15041164; 15051500; 15066699; 15068623; 15078471; 15115662; 15120189; 15135368; 15162834; 15166131; 15170937; 15182335; 15189946; 15194285; 15200452; 15207246; 15214940; 15215891; 15235581; 15247172; 15251440; 15265425; 15271977; 15297269; 15316224; 15320903; 15322002; 15322007; 15324937; 15327519; 15345584; 15347683; 15361128; 15361241; 15367434; 15372109; 15374002; 15381817; 15390286; 15448160; 15458467; 15462469; 15481145; 15489334; 15498860; 15499631; 15501397; 15511228; 15522880; 15550390; 15556691; 15570643; 15580300; 15585559; 15599305; 15603866; 15604419; 15611657; 15621151; 15624893; 15628695; 15634895; 15638726; 15643599; 15644127; 15652446; 15661939; 15674394; 15675129; 15679925; 15681246; 15681825; 15695523; 15708894; 15709194; 15710386; 15718915; 15725351; 15731046; 15733644; 15737643; 15749687; 15763337; 15773449; 15778222; 15780879; 15784411; 15800938; 15811521; 15815688; 15816837; 15818327; 15841043; 15842590; 15853924; 15858598; 15870936; 15880044; 15890243; 15900487; 15901906; 15905622; 15919929; 15925543; 15931634; 15932621; 15932627; 15935691; 15936090; 15941525; 15944226; 15944319; 15950283; 15969687; 15979955; 15985639; 15992611; 16002423; 16014948; 16024776; 16024856; 16034083; 16051062; 16051377; 16051797; 16085646; 16098562; 16108727; 16115485; 16127458; 16129616; 16148108; 16148152; 16160188; 16166103; 16182624; 16183136; 16200827; 16201318; 16204617; 16210653; 16216674; 16220542; 16232344; 16243534; 16257975; 16263796; 16266858; 16280321; 16302211; 16310045; 16318585; 16323127; 16364177; 16367922; 16375755; 16378074; 16386594; 16391178; 16403098; 16409297; 16410273; 16421220; 16425360; 16427044; 16427155; 16430971; 16433832; 16434471; 16474934; 16476013; 16478776; 16484229; 16487026; 16487180; 16493441; 16504056; 16538877; 16540751; 16567828; 16574426; 16616105; 16621981; 16647017; 16672072; 16678358; 16681592; 16689860; 16690980; 16704689; 16718821; 16720107; 16723718; 16724074; 16730575; 16737571; 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22767256; 22778764; 22784413; 22805115; 22809599; 22814515; 22815836; 22824211; 22826629; 22847200; 22851706; 22880090; 22882906; 22885102; 22896630; 22898392; 22924705; 22932225; 22952667; 22983442; 22983646; 22986484; 22992806; 23028695; 23040881; 23045477; 23061992; 23071273; 23077565; 23101722; 23107828; 23125442; 23128233; 23133532; 23133672; 23139419; 23152883; 23159874; 23179933; 23185315; 23213275; 23223131; 23224615; 23240025; 23243276; 23252864; 23253667; 23255246; 23259293; 23265966; 23271704; 23280240; 23289765; 23295883; 23321919; 23343479; 23349093; 23359533; 23362867; 23378427; 23388331; 23401468; 23404187; 23412855; 23416458; 23449998; 23460743; 23461851; 23462597; 23487038; 23507374; 23582260; 23592910; 23632060; 23638863; 23639073; 23685791; 23692034; 23711712; 23720660; 23737189; 23740952; 23785756; 23786562; 23793505; 23803376; 23806637; 23811275; 23857000; 23874969; 23880295; 23891168; 23901078; 23998448; 24012417; 24055710; 24088808; 24140406; 24313836; 24459820 interferon, gamma Ensembl:ENSG00000111537 HGNC:5438 HPRD:00957 MIM:147570 Vega:OTTHUMG00000169113 IFNG Bin Zhao, Yue Liu, Oliver He IGF-I IGF1A IGFI WEB: http://www.ncbi.nlm.nih.gov/gene IGF1 insulin-like growth factor 1 (somatomedin C) 3479 12q23.2 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0001501 (EC: TAS, PMID: 10448861); GO_0001974 (EC: IEA); GO_0002576 (EC: TAS); GO_0005158 (EC: IPI, PMID: 8452530); GO_0005159 (EC: IPI, PMID: 8452530); GO_0005178 (EC: IDA, PMID: 19578119); GO_0005179 (EC: IDA, PMID: 7188854); GO_0005515 (EC: IPI, PMID: 10766744); GO_0005576 (EC: NAS, PMID: 14718574); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 17119061); GO_0005886 (EC: TAS); GO_0006260 (EC: TAS, PMID: 10766744); GO_0006928 (EC: TAS, PMID: 10766744); GO_0007165 (EC: TAS, PMID: 10448861); GO_0007265 (EC: TAS, PMID: 10848592); GO_0007517 (EC: TAS, PMID: 10448861); GO_0007596 (EC: TAS); GO_0008083 (EC: IEA); GO_0008284 (EC: IDA, PMID: 12746903); GO_0008285 (EC: IEA); GO_0009441 (EC: TAS, PMID: 10448861); GO_0010001 (EC: IEA); GO_0010613 (EC: IDA, PMID: 19654000); GO_0014068 (EC: IDA, PMID: 7688386); GO_0014834 (EC: IDA, PMID: 17531227); GO_0014896 (EC: IMP, PMID: 10191278); GO_0014904 (EC: IDA, PMID: 17531227); GO_0014911 (EC: IDA, PMID: 10766744); GO_0016942 (EC: IC, PMID: 10766744); GO_0021940 (EC: IEA); GO_0030104 (EC: IEA); GO_0030166 (EC: IDA, PMID: 12746903); GO_0030168 (EC: TAS); GO_0030879 (EC: IEA); GO_0031017 (EC: IEA); GO_0031093 (EC: TAS); GO_0032878 (EC: IEA); GO_0033160 (EC: IDA, PMID: 19654000); GO_0034392 (EC: IDA, PMID: 16942485); GO_0035264 (EC: IEA); GO_0035630 (EC: IDA, PMID: 16433617); GO_0040014 (EC: IEP, PMID: 8421089); GO_0042104 (EC: IDA, PMID: 15694994); GO_0042523 (EC: IDA, PMID: 9722506); GO_0043388 (EC: IDA, PMID: 19654000); GO_0043410 (EC: IDA, PMID: 19654000); GO_0043568 (EC: IDA, PMID: 10766744); GO_0044267 (EC: TAS); GO_0045445 (EC: IDA, PMID: 17531227); GO_0045669 (EC: IDA, PMID: 16433617); GO_0045725 (EC: IDA); GO_0045740 (EC: IDA, PMID: 7688386); GO_0045740 (EC: ISS); GO_0045821 (EC: IDA, PMID: 7688386); GO_0045840 (EC: IDA, PMID: 10644978); GO_0045893 (EC: IDA, PMID: 19654000); GO_0045944 (EC: IDA, PMID: 16433617); GO_0046326 (EC: IDA); GO_0046579 (EC: IDA, PMID: 9722506); GO_0048009 (EC: IEA); GO_0048015 (EC: IDA, PMID: 7692086); GO_0048146 (EC: IDA, PMID: 7188854); GO_0048286 (EC: IEA); GO_0048661 (EC: IDA, PMID: 10766744); GO_0048754 (EC: IEA); GO_0048839 (EC: IEA); GO_0050650 (EC: IEA); GO_0050679 (EC: IDA, PMID: 7188854); GO_0050731 (EC: IDA, PMID: 7782332); GO_0051450 (EC: IDA, PMID: 17531227); GO_0051897 (EC: IEA); GO_0060426 (EC: IEA); GO_0060463 (EC: IEA); GO_0060509 (EC: IEA); GO_0060510 (EC: IEA); GO_0060527 (EC: IEA); GO_0060736 (EC: IEA); GO_0060741 (EC: IEA); GO_0060766 (EC: IEA); GO_0070373 (EC: IEA); GO_0070886 (EC: IDA, PMID: 19654000); GO_0090201 (EC: ISS); GO_0097192 (EC: IEA); GO_2000288 (EC: IEA); GO_2001237 (EC: IDA, PMID: 16942485) PMID: 632300; 1147105; 1319992; 1370435; 1372070; 1383255; 1733942; 1791841; 1852007; 2018498; 2036417; 2082190; 2752154; 2935423; 2937782; 2982726; 3002851; 3242681; 3455760; 3683205; 4550398; 6189745; 6358902; 6382022; 7188854; 7511544; 7683646; 7688386; 7692086; 7720641; 7782332; 7916968; 8421089; 8452530; 8495408; 8857020; 8939990; 9138096; 9446566; 9453236; 9497324; 9681507; 9722506; 9722589; 9831081; 9853872; 9857239; 10084601; 10191278; 10205209; 10226805; 10350456; 10381171; 10391209; 10407151; 10448861; 10459853; 10512690; 10644978; 10749889; 10766744; 10823924; 10848592; 11063745; 11161840; 11175789; 11246885; 11319179; 11344214; 11600567; 11735247; 11749962; 11762714; 11768601; 11787050; 11822578; 11825899; 11834727; 11857446; 11858767; 11867942; 11877395; 11877670; 11896491; 11897674; 11903419; 11904589; 11907830; 11909998; 11914023; 11914026; 11924928; 11937187; 11943599; 11953210; 11964397; 11972897; 11988840; 11994280; 11994678; 12005306; 12006706; 12011046; 12011225; 12032677; 12050240; 12062094; 12070137; 12086966; 12095637; 12102164; 12111701; 12115549; 12122101; 12127559; 12135130; 12135360; 12164325; 12175483; 12186542; 12201212; 12213898; 12217887; 12218293; 12236578; 12237896; 12240900; 12356750; 12364325; 12381752; 12388463; 12389335; 12394769; 12397390; 12419777; 12424437; 12477932; 12508915; 12508916; 12508917; 12508918; 12508929; 12508940; 12509920; 12511011; 12519841; 12545204; 12555073; 12562960; 12571183; 12590635; 12590636; 12592062; 12610514; 12612059; 12631341; 12642873; 12679458; 12714114; 12716804; 12716855; 12716875; 12727948; 12729801; 12730416; 12732844; 12734180; 12735930; 12746292; 12746903; 12759337; 12787886; 12791939; 12800944; 12810534; 12842994; 12843178; 12843179; 12843187; 12858577; 12861174; 12865482; 12867429; 12870155; 12891709; 12909598; 12915683; 12919702; 12930919; 12937269; 12937290; 12943991; 12948293; 12949013; 12960100; 12970325; 13130502; 14504195; 14521955; 14557458; 14602779; 14604834; 14605256; 14631161; 14633859; 14647921; 14657423; 14668202; 14673951; 14674122; 14681231; 14684598; 14684690; 14690534; 14691011; 14691340; 14693733; 14697248; 14710345; 14710346; 14710359; 14714750; 14715837; 14718574; 14744783; 14749262; 14757186; 14761840; 14764950; 14961074; 14973173; 15033176; 15033949; 15044591; 15047131; 15049048; 15067513; 15072640; 15082485; 15086466; 15087580; 15090033; 15098919; 15105834; 15134305; 15135045; 15140223; 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24511663 insulin-like growth factor 1 (somatomedin C) Ensembl:ENSG00000017427 HGNC:5464 HPRD:00936 MIM:147440 Vega:OTTHUMG00000149910 IGF1 Bin Zhao, Yue Liu, Oliver He CD221 IGFIR IGFR JTK13 WEB: http://www.ncbi.nlm.nih.gov/gene IGF1R insulin-like growth factor 1 receptor 3480 15q26.3 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0001965 (EC: IEA); GO_0004713 (EC: IDA, PMID: 11162456); GO_0004713 (EC: TAS); GO_0005010 (EC: IDA, PMID: 7679099); GO_0005158 (EC: IDA, PMID: 8452530); GO_0005515 (EC: IPI, PMID: 10026153); GO_0005520 (EC: IDA, PMID: 1846292); GO_0005524 (EC: IEA); GO_0005886 (EC: TAS); GO_0005887 (EC: IC, PMID: 7679099); GO_0005901 (EC: IEA); GO_0006955 (EC: IMP, PMID: 16886151); GO_0007165 (EC: TAS, PMID: 3003744); GO_0007409 (EC: IEA); GO_0007420 (EC: IEA); GO_0008284 (EC: TAS, PMID: 10749889); GO_0008286 (EC: TAS, PMID: 10829031); GO_0010656 (EC: IEA); GO_0014065 (EC: IC, PMID: 7541045); GO_0016020 (EC: IDA, PMID: 8452530); GO_0018108 (EC: IDA, PMID: 11162456); GO_0018108 (EC: TAS); GO_0030010 (EC: IEA); GO_0030238 (EC: IEA); GO_0030335 (EC: IMP, PMID: 12138094); GO_0030879 (EC: IEA); GO_0031017 (EC: IEA); GO_0031994 (EC: IPI, PMID: 8452530); GO_0032467 (EC: IEA); GO_0033197 (EC: IEA); GO_0042802 (EC: IPI, PMID: 11448933); GO_0043005 (EC: IEA); GO_0043066 (EC: IDA, PMID: 12556535); GO_0043231 (EC: IDA, PMID: 8452530); GO_0043235 (EC: IDA); GO_0043410 (EC: IEA); GO_0043548 (EC: IPI, PMID: 7541045); GO_0043559 (EC: IPI, PMID: 8452530); GO_0043560 (EC: IPI, PMID: 7541045); GO_0045740 (EC: IMP, PMID: 12138094); GO_0046328 (EC: IDA, PMID: 12556535); GO_0046777 (EC: IDA, PMID: 11162456); GO_0048009 (EC: IDA, PMID: 7679099); GO_0048015 (EC: IDA, PMID: 7692086); GO_0051262 (EC: IDA, PMID: 1846292); GO_0051291 (EC: IEA); GO_0051389 (EC: IDA, PMID: 12556535); GO_0051897 (EC: IEA); GO_0051898 (EC: IEA); GO_0060740 (EC: IEA); GO_0090031 (EC: IEA) PMID: 1316909; 1711844; 1846292; 1850606; 1851182; 1852007; 2877871; 2948220; 3003744; 3107886; 7541045; 7559507; 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20734064; 20736806; 20800603; 20818434; 20819078; 20837466; 20847162; 20871634; 20881960; 20927124; 20935157; 20940305; 20950153; 20962017; 20976540; 21041409; 21046444; 21047277; 21048031; 21057462; 21075859; 21122407; 21123183; 21124078; 21139048; 21139137; 21147068; 21152401; 21159245; 21177763; 21197570; 21204214; 21212273; 21217522; 21251749; 21258401; 21273178; 21292299; 21304894; 21317933; 21330319; 21338601; 21340542; 21372220; 21388493; 21393993; 21396585; 21402719; 21410323; 21442237; 21447702; 21447712; 21450456; 21471532; 21524684; 21538027; 21546606; 21574055; 21595894; 21611203; 21620944; 21645859; 21654344; 21677036; 21677874; 21685939; 21687694; 21713359; 21728395; 21729677; 21732141; 21748295; 21799000; 21807868; 21811077; 21832049; 21840990; 21845403; 21852217; 21862872; 21866554; 21873172; 21890473; 21908557; 21931726; 21939528; 21943825; 21958043; 21959795; 21963094; 21972777; 21987572; 21988832; 21994939; 22020193; 22020329; 22033326; 22042973; 22044563; 22058336; 22115178; 22115966; 22120672; 22128190; 22130793; 22133293; 22140443; 22146489; 22161861; 22172258; 22179513; 22188815; 22194466; 22218435; 22235273; 22246875; 22261717; 22268729; 22275271; 22285568; 22303694; 22309212; 22325222; 22335030; 22336232; 22339909; 22343486; 22348393; 22354554; 22372631; 22394253; 22406993; 22419550; 22424712; 22438913; 22495974; 22506015; 22508822; 22509025; 22541124; 22555179; 22572840; 22614005; 22623732; 22626974; 22635104; 22682017; 22685298; 22700994; 22710713; 22738321; 22767591; 22777769; 22825921; 22875931; 22879999; 22892600; 22894899; 22909219; 22931894; 22932330; 22935141; 22939624; 22939629; 22972910; 22998174; 23000965; 23056576; 23082760; 23106397; 23109135; 23118311; 23152410; 23188799; 23190452; 23239200; 23250396; 23252569; 23263486; 23266446; 23288662; 23314677; 23331867; 23354097; 23360921; 23365645; 23374155; 23395167; 23402816; 23404184; 23416929; 23418605; 23431408; 23453369; 23460259; 23507142; 23515613; 23526299; 23527719; 23531874; 23539445; 23548939; 23549953; 23564324; 23619944; 23664098; 23675407; 23689439; 23696648; 23704881; 23710710; 23724116; 23730215; 23744486; 23782942; 23792093; 23797814; 23801064; 23814047; 23818948; 23821363; 23831640; 23861377; 23861540; 23867124; 23873272; 23879873; 23899556; 23962053; 23980150; 23990442; 23994953; 24055032; 24135282; 24285539; 24307738 insulin-like growth factor 1 receptor Ensembl:ENSG00000140443 HGNC:5465 HPRD:00932 MIM:147370 Vega:OTTHUMG00000149851 IGF1R Bin Zhao, Yue Liu, Oliver He IKK-beta IKK2 IKKB IMD15 NFKBIKB WEB: http://www.ncbi.nlm.nih.gov/gene IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 3551 8p11.2 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0001782 (EC: IEA); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004672 (EC: IDA); GO_0004674 (EC: TAS); GO_0005515 (EC: IPI, PMID: 10521409); GO_0005524 (EC: IEA); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0006468 (EC: IDA); GO_0006468 (EC: NAS, PMID: 9346484); GO_0006954 (EC: TAS, PMID: 18626576); GO_0007249 (EC: TAS, PMID: 18626576); GO_0007252 (EC: TAS, PMID: 18626576); GO_0008384 (EC: TAS, PMID: 18626576); GO_0008385 (EC: TAS, PMID: 18626576); GO_0009615 (EC: TAS, PMID: 18626576); GO_0009898 (EC: ISS); GO_0010765 (EC: IEA); GO_0019901 (EC: IPI, PMID: 12492477); GO_0032481 (EC: TAS); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035631 (EC: ISS); GO_0035666 (EC: TAS); GO_0035872 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042501 (EC: IDA); GO_0042803 (EC: IDA); GO_0043066 (EC: TAS); GO_0043123 (EC: TAS); GO_0045087 (EC: TAS, PMID: 18626576); GO_0045121 (EC: IEA); GO_0045893 (EC: NAS, PMID: 9346484); GO_0045944 (EC: IDA); GO_0046982 (EC: IDA); GO_0048011 (EC: TAS); GO_0050852 (EC: TAS); GO_0051092 (EC: IDA, PMID: 15790681); GO_0051092 (EC: TAS, PMID: 18626576); GO_0070423 (EC: TAS); GO_0071356 (EC: IDA); GO_2001259 (EC: IEA) PMID: 8601309; 8657102; 9214631; 9252186; 9346241; 9346484; 9346485; 9520446; 9632806; 9689078; 9721103; 9744859; 9751059; 9751060; 9763654; 9813230; 9819420; 9878263; 9891086; 9914500; 10022904; 10195894; 10356400; 10469655; 10485711; 10497169; 10521409; 10713178; 10722755; 10723127; 10733566; 10755617; 10779355; 10783893; 10807933; 10848580; 10962033; 10968790; 10980203; 11002417; 11057907; 11080499; 11096118; 11113112; 11120819; 11158290; 11278268; 11359906; 11429546; 11460167; 11527961; 11585904; 11594795; 11606564; 11777949; 11815618; 11821416; 11830587; 11839743; 11864612; 11945026; 11954826; 11959143; 11971985; 11976329; 12054687; 12070292; 12133833; 12210728; 12244103; 12351658; 12393548; 12411322; 12459277; 12477932; 12482991; 12486103; 12486112; 12492477; 12547194; 12589056; 12612076; 12637324; 12645577; 12657630; 12707358; 12709429; 12842894; 12890679; 12943667; 14514672; 14560022; 14585846; 14585847; 14585990; 14597638; 14625285; 14654787; 14702039; 14715628; 14743216; 14990741; 15084260; 15125834; 15128824; 15140882; 15184390; 15217951; 15218148; 15226300; 15254232; 15276183; 15319427; 15383283; 15389287; 15456791; 15489227; 15489334; 15492226; 15494311; 15564333; 15601829; 15749833; 15761153; 15790681; 15802604; 15808510; 15837793; 15856005; 15856023; 15880043; 15951441; 16024783; 16046471; 16051665; 16082226; 16123045; 16126728; 16135815; 16177806; 16207722; 16267042; 16280329; 16286467; 16291755; 16319058; 16344560; 16365431; 16393995; 16424386; 16497931; 16547522; 16583354; 16603398; 16611882; 16728640; 16840786; 16906147; 16920630; 16938294; 16966325; 16982623; 16989899; 16997282; 16998237; 17000764; 17016640; 17047224; 17079871; 17114296; 17145747; 17182689; 17213322; 17237423; 17244613; 17287217; 17363905; 17363973; 17419715; 17446166; 17466952; 17568778; 17616684; 17684021; 17693255; 17703412; 17891179; 17939994; 17947699; 17962807; 17977820; 17997719; 18029348; 18037881; 18163512; 18180283; 18207244; 18260825; 18266324; 18266467; 18308615; 18316610; 18362886; 18408758; 18411264; 18434448; 18456659; 18490760; 18571841; 18583959; 18600306; 18626576; 18636537; 18657515; 18692471; 18949366; 18952604; 18957422; 18981174; 18990758; 19050262; 19104039; 19109741; 19141566; 19150425; 19196987; 19202066; 19243472; 19258923; 19270264; 19365808; 19422324; 19453261; 19488402; 19526344; 19573080; 19591457; 19594441; 19656241; 19675099; 19716809; 19728335; 19730683; 19773279; 19786027; 19815509; 19818716; 19820708; 19850743; 20005846; 20007573; 20026656; 20051109; 20056178; 20068038; 20098747; 20145131; 20152798; 20164171; 20167598; 20176108; 20331378; 20347815; 20368414; 20371626; 20410276; 20421348; 20434986; 20448038; 20448286; 20449947; 20465575; 20503287; 20529849; 20568250; 20600852; 20614026; 20627395; 20657549; 20693425; 20797629; 20803413; 20856938; 20925653; 20932476; 20933503; 20977779; 21029719; 21048031; 21139048; 21204785; 21220427; 21248029; 21317297; 21331078; 21344388; 21390216; 21399639; 21474709; 21482671; 21575199; 21606193; 21606198; 21670849; 21703539; 21724995; 21784860; 21798539; 21803029; 21810613; 21811235; 21903422; 21911292; 21985298; 21987722; 21988832; 21993219; 22022389; 22099304; 22262057; 22331067; 22511786; 22605335; 22637744; 22766331; 22824620; 22848663; 22863883; 22891964; 22955948; 22990857; 23007157; 23016877; 23017601; 23032264; 23069812; 23090968; 23108365; 23123196; 23178494; 23349803; 23386606; 23453969; 23589370; 23636414; 23732909; 23743204; 23776175; 23776406; 23792959; 23817200; 23872070; 23974204; 23986494; 24127568; 24240172; 24266532; 24369075 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta Ensembl:ENSG00000104365 HGNC:5960 HPRD:04462 MIM:603258 Vega:OTTHUMG00000164092 IKBKB Bin Zhao, Yue Liu, Oliver He IL-1A IL1 IL1-ALPHA IL1F1 WEB: http://www.ncbi.nlm.nih.gov/gene IL1A interleukin 1, alpha 3552 2q14 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0001660 (EC: IEA); GO_0005125 (EC: IMP, PMID: 2989698); GO_0005149 (EC: IEA); GO_0005507 (EC: IDA, PMID: 12746488); GO_0005515 (EC: IPI, PMID: 12746488); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 12746488); GO_0005615 (EC: IMP, PMID: 3493774); GO_0005829 (EC: IDA, PMID: 12746488); GO_0006915 (EC: TAS, PMID: 1924307); GO_0006954 (EC: TAS, PMID: 6209582); GO_0006955 (EC: IEA); GO_0008283 (EC: TAS, PMID: 6209582); GO_0008285 (EC: IDA, PMID: 3493774); GO_0010575 (EC: ISS); GO_0019221 (EC: IMP, PMID: 2989698); GO_0034605 (EC: IDA, PMID: 12746488); GO_0035234 (EC: IEA); GO_0045086 (EC: IMP, PMID: 2989698); GO_0045766 (EC: ISS); GO_0045840 (EC: IMP, PMID: 2989698); GO_0045944 (EC: IEA); GO_0046688 (EC: IDA, PMID: 12746488); GO_0050715 (EC: IDA, PMID: 1739124); GO_0051781 (EC: IEA); GO_0097192 (EC: IEA); GO_2001240 (EC: TAS, PMID: 10748004) PMID: 1548758; 1584804; 1675504; 1739124; 1905933; 1924307; 1993354; 2346741; 2536171; 2635664; 2783369; 2946959; 2989698; 2994016; 3281727; 3485152; 3486405; 3493774; 6209582; 7494249; 7499244; 7511078; 7526541; 7561697; 7566121; 7695626; 7706435; 7815507; 7818827; 7857652; 7878046; 8188271; 8346241; 8370968; 8436814; 8458986; 8621446; 8764000; 8892361; 8938574; 9108403; 9169134; 9185130; 9225992; 9658081; 9820540; 10441334; 10512743; 10625660; 10744718; 10748004; 10854325; 10860666; 10861041; 10953177; 10998424; 11065142; 11079552; 11093146; 11138328; 11145356; 11145836; 11233912; 11241561; 11264025; 11278614; 11350500; 11350506; 11423389; 11427627; 11436125; 11448121; 11453239; 11466363; 11554782; 11574262; 11640949; 11669478; 11703512; 11737511; 11774556; 11774564; 11777547; 11784248; 11790645; 11840488; 11858158; 11895290; 11895546; 11911995; 11921766; 11930657; 11940570; 11956022; 11991668; 11991722; 12028539; 12034804; 12037600; 12047332; 12051868; 12052540; 12052541; 12070246; 12082592; 12089333; 12100571; 12101079; 12102486; 12115161; 12115182; 12140751; 12149413; 12161036; 12164325; 12195069; 12209090; 12210881; 12212456; 12218254; 12220547; 12242547; 12362317; 12370389; 12390476; 12404162; 12425801; 12445219; 12445604; 12453471; 12477932; 12519748; 12528118; 12528119; 12530978; 12558814; 12558933; 12562360; 12598547; 12613995; 12622850; 12626603; 12631337; 12641660; 12651617; 12667716; 12673844; 12702109; 12710950; 12714264; 12729191; 12730545; 12737276; 12742380; 12746420; 12746488; 12749050; 12752101; 12752325; 12759172; 12782964; 12794386; 12801479; 12824054; 12869004; 12874528; 12890860; 12899665; 12901853; 12913118; 12928052; 12928381; 12930304; 12930389; 12931024; 12946945; 12947160; 12974682; 13679381; 14514232; 14533660; 14566095; 14584862; 14612453; 14633625; 14634838; 14639688; 14644395; 14656692; 14664464; 14672899; 14673470; 14674121; 14688369; 14693849; 14705223; 14735144; 14974822; 14983027; 14984963; 14986816; 14997019; 15007345; 15009111; 15036245; 15039285; 15050696; 15068111; 15082121; 15117956; 15130917; 15170937; 15190266; 15201366; 15219382; 15220553; 15238767; 15248873; 15270852; 15308963; 15338333; 15341923; 15351436; 15361128; 15377701; 15381245; 15465625; 15468358; 15476179; 15481145; 15489227; 15489334; 15514971; 15551344; 15561982; 15562658; 15562910; 15563458; 15566952; 15581980; 15587751; 15592292; 15633328; 15638425; 15679580; 15679582; 15694997; 15723707; 15726267; 15727567; 15732864; 15733644; 15737206; 15745939; 15777329; 15797878; 15830637; 15836820; 15854776; 15931231; 15951664; 15954918; 15974847; 15986200; 16021081; 16030091; 16046471; 16078996; 16100774; 16101131; 16106254; 16115908; 16155691; 16159520; 16160188; 16206345; 16226351; 16230423; 16246569; 16268484; 16291395; 16304445; 16317381; 16318580; 16361815; 16369899; 16375755; 16378839; 16384981; 16389181; 16403098; 16410064; 16410066; 16411061; 16428739; 16433908; 16464738; 16478776; 16504015; 16508980; 16510430; 16517748; 16546408; 16564702; 16564703; 16567828; 16573560; 16619041; 16636934; 16684536; 16702372; 16708852; 16719905; 16720107; 16733901; 16788102; 16792821; 16814297; 16842617; 16856121; 16879223; 16885196; 16888077; 16900886; 16905534; 16907768; 16911569; 16918024; 16930778; 16931944; 16934308; 16938461; 16945028; 16961803; 16965524; 16965825; 16971486; 16978691; 17002905; 17012236; 17034724; 17083033; 17138334; 17140155; 17141301; 17149369; 17179726; 17197697; 17205326; 17214636; 17244613; 17257312; 17290104; 17293495; 17309781; 17331078; 17335370; 17335371; 17335373; 17348886; 17353161; 17355643; 17360358; 17369174; 17371964; 17378887; 17388919; 17391495; 17436000; 17440718; 17444587; 17444864; 17448042; 17449468; 17458495; 17460270; 17471097; 17473736; 17477815; 17492470; 17500214; 17507369; 17532232; 17541168; 17549071; 17573384; 17575917; 17584583; 17596594; 17610660; 17621543; 17622713; 17627763; 17638785; 17703412; 17711477; 17716546; 17717316; 17823082; 17889143; 17907045; 17919610; 17926179; 17932347; 17941080; 17948066; 17949817; 17954336; 17960403; 17964974; 17978470; 17986158; 17997719; 18024394; 18038187; 18052703; 18063673; 18085494; 18086816; 18157711; 18158110; 18166103; 18199150; 18211631; 18271063; 18278133; 18284424; 18288454; 18292602; 18306451; 18315433; 18321309; 18322311; 18329368; 18336824; 18361934; 18393655; 18395750; 18416755; 18416756; 18441098; 18469698; 18484169; 18484691; 18496214; 18498295; 18510611; 18576312; 18583979; 18587204; 18607773; 18615092; 18615110; 18624935; 18628242; 18628526; 18631256; 18632425; 18633131; 18666137; 18673406; 18676404; 18676680; 18676870; 18702109; 18708672; 18709454; 18714935; 18716798; 18717723; 18723088; 18760325; 18763028; 18773331; 18787502; 18815552; 18818748; 18821666; 18832862; 18834321; 18838388; 18941541; 18952231; 18971305; 18974840; 18974842; 18976975; 19012493; 19013788; 19019335; 19026558; 19028820; 19035492; 19042953; 19046297; 19053923; 19066720; 19074885; 19076825; 19086955; 19088500; 19099590; 19110536; 19117745; 19131662; 19141488; 19141860; 19155622; 19158434; 19170196; 19180518; 19180798; 19184295; 19188531; 19191034; 19194673; 19204921; 19225544; 19240061; 19247692; 19247983; 19258923; 19263529; 19267917; 19279357; 19280228; 19290009; 19294239; 19307598; 19332120; 19336370; 19336475; 19348329; 19408823; 19431193; 19435817; 19453261; 19470040; 19479237; 19497711; 19505916; 19527514; 19546559; 19559392; 19563289; 19573080; 19594368; 19625176; 19648252; 19658300; 19661089; 19671938; 19680808; 19683555; 19684156; 19692168; 19701653; 19702713; 19708438; 19729601; 19733643; 19738620; 19742166; 19764937; 19773279; 19773451; 19775068; 19786079; 19789190; 19792847; 19805069; 19811432; 19820020; 19844779; 19860911; 19884766; 19889475; 19892918; 19913121; 19917630; 19926874; 19934104; 19948975; 20005085; 20011938; 20027454; 20056178; 20059417; 20059631; 20065999; 20070880; 20080142; 20113359; 20113413; 20116409; 20127018; 20131253; 20140262; 20141484; 20157068; 20169140; 20173430; 20178882; 20182449; 20192980; 20196868; 20200332; 20207250; 20213229; 20217044; 20220089; 20227257; 20237496; 20299682; 20335539; 20347268; 20353565; 20371868; 20400062; 20413850; 20418110; 20427258; 20445556; 20452482; 20453000; 20459687; 20472930; 20490394; 20490891; 20495422; 20503287; 20534741; 20536507; 20536609; 20551628; 20561568; 20565898; 20568250; 20574532; 20594066; 20595916; 20602615; 20603037; 20603050; 20619343; 20628086; 20630038; 20673868; 20677014; 20725607; 20800603; 20811626; 20844546; 20847078; 20848459; 20889944; 20934174; 20940514; 20942594; 20959405; 20961668; 21035110; 21037510; 21048327; 21054222; 21070631; 21086908; 21107309; 21133705; 21154765; 21196890; 21205020; 21235388; 21270123; 21279638; 21311438; 21336718; 21385326; 21393239; 21394384; 21449691; 21509504; 21518761; 21620624; 21621860; 21682548; 21712624; 21768915; 21795706; 21816944; 21847358; 21871094; 21968104; 22083707; 22092925; 22124068; 22143786; 22151432; 22153345; 22177239; 22197408; 22211888; 22216303; 22234841; 22282663; 22285242; 22312160; 22344672; 22348697; 22364598; 22417897; 22513697; 22582837; 22633328; 22675954; 22678894; 22732089; 22795294; 22805136; 22868802; 22879895; 22894561; 22949675; 23018032; 23052182; 23076369; 23100272; 23159404; 23203659; 23216199; 23241110; 23271701; 23289806; 23322030; 23349093; 23395675; 23454256; 23509928; 23527710; 23542780; 23554905; 23592003; 23639700; 23645090; 23723976; 23747396; 23846687; 23900673; 23927441; 24060296; 24062309; 24103372; 24146121; 24265545; 24273934; 24275344; 24313836 interleukin 1, alpha HGNC:5991 HPRD:00988 MIM:147760 IL1A Bin Zhao, Yue Liu, Oliver He IL-1 IL1-BETA IL1F2 WEB: http://www.ncbi.nlm.nih.gov/gene IL1B interleukin 1, beta 3553 2q14 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0000165 (EC: IMP); GO_0000187 (EC: IDA, PMID: 10748004); GO_0001660 (EC: IEA); GO_0001934 (EC: IDA, PMID: 10748004); GO_0001934 (EC: NAS, PMID: 16477012); GO_0002711 (EC: IC, PMID: 1919436); GO_0005125 (EC: IDA, PMID: 1919436); GO_0005125 (EC: IMP, PMID: 2989698); GO_0005149 (EC: NAS, PMID: 1919436); GO_0005576 (EC: IDA); GO_0005576 (EC: NAS, PMID: 1919436); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 12483741); GO_0005615 (EC: IMP, PMID: 3493774); GO_0005829 (EC: TAS); GO_0006915 (EC: TAS, PMID: 9218611); GO_0006954 (EC: IDA, PMID: 10748004); GO_0006954 (EC: NAS, PMID: 1919436); GO_0006955 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10786823); GO_0007267 (EC: TAS, PMID: 2989698); GO_0007566 (EC: TAS, PMID: 16720713); GO_0008285 (EC: IDA, PMID: 3493774); GO_0009743 (EC: IEA); GO_0010575 (EC: IDA, PMID: 12958148); GO_0010575 (EC: ISS); GO_0010829 (EC: ISS, PMID: 16865359); GO_0014805 (EC: NAS, PMID: 16477012); GO_0019221 (EC: IDA, PMID: 10748004); GO_0019904 (EC: IPI, PMID: 16575408); GO_0030141 (EC: IEA); GO_0030213 (EC: IDA, PMID: 15100360); GO_0030593 (EC: IEA); GO_0030730 (EC: IDA, PMID: 19032770); GO_0030949 (EC: IC, PMID: 12958148); GO_0031622 (EC: ISS); GO_0031663 (EC: IDA); GO_0032308 (EC: ISS); GO_0032611 (EC: IEA); GO_0032725 (EC: IDA); GO_0032729 (EC: IDA); GO_0032755 (EC: TAS, PMID: 16865359); GO_0032757 (EC: IDA, PMID: 19524870); GO_0033129 (EC: NAS); GO_0033198 (EC: IEA); GO_0034116 (EC: IDA, PMID: 15100360); GO_0034116 (EC: NAS, PMID: 19281832); GO_0035066 (EC: NAS); GO_0035234 (EC: IEA); GO_0035505 (EC: IDA, PMID: 18390750); GO_0035690 (EC: IDA, PMID: 19158679); GO_0042102 (EC: IDA, PMID: 1919436); GO_0042346 (EC: IDA, PMID: 18390750); GO_0043122 (EC: IDA, PMID: 10748004); GO_0043123 (EC: IEA); GO_0043407 (EC: ISS, PMID: 16865359); GO_0043491 (EC: IMP); GO_0045080 (EC: IEA); GO_0045086 (EC: IMP, PMID: 2989698); GO_0045410 (EC: IEA); GO_0045429 (EC: IDA, PMID: 8383325); GO_0045766 (EC: ISS); GO_0045833 (EC: ISS, PMID: 16865359); GO_0045840 (EC: IMP, PMID: 2989698); GO_0045893 (EC: IDA, PMID: 15100360); GO_0045944 (EC: IEA); GO_0046330 (EC: IEA); GO_0046627 (EC: ISS, PMID: 16865359); GO_0046827 (EC: NAS, PMID: 19281832); GO_0050796 (EC: IDA, PMID: 8383325); GO_0050995 (EC: IDA, PMID: 19032770); GO_0050996 (EC: ISS, PMID: 16865359); GO_0051044 (EC: IDA, PMID: 18373975); GO_0051091 (EC: IDA, PMID: 10748004); GO_0051092 (EC: IDA, PMID: 10383454); GO_0051781 (EC: IEA); GO_0060355 (EC: NAS, PMID: 19281832); GO_0060559 (EC: IDA, PMID: 16720713); GO_0070164 (EC: ISS, PMID: 16865359); GO_0070487 (EC: IDA, PMID: 15100360); GO_0071260 (EC: IEP, PMID: 19593445); GO_0071310 (EC: IDA, PMID: 19158679); GO_0071407 (EC: IDA); GO_0071639 (EC: IDA, PMID: 19524870); GO_0097192 (EC: IEA); GO_2001240 (EC: IDA, PMID: 10748004) PMID: 1548758; 1753956; 1835838; 1837236; 1905933; 1907279; 1918997; 1919001; 1919436; 1993354; 2001363; 2137098; 2372550; 2466831; 2536171; 2585509; 2602367; 2635664; 2898301; 2946959; 2954882; 2989698; 3259176; 3264123; 3281727; 3490654; 3493774; 6083565; 6209582; 7494249; 7511078; 7526541; 7561697; 7642516; 7706435; 7797510; 7815507; 7818827; 7878046; 7981229; 8188271; 8383325; 8432529; 8537091; 8663297; 8764000; 8852605; 8869030; 8892361; 8939574; 9062193; 9108403; 9169134; 9185130; 9218611; 9225992; 9230816; 9288832; 9378998; 9658081; 9714181; 9820540; 10339575; 10358063; 10383454; 10438928; 10512743; 10625660; 10744718; 10746728; 10748004; 10756100; 10779559; 10786823; 10854325; 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21978003; 21988351; 21992747; 21994456; 22003203; 22010855; 22019906; 22021895; 22023756; 22027397; 22059992; 22064385; 22065068; 22068351; 22071871; 22072054; 22073249; 22073367; 22092925; 22095718; 22101739; 22103356; 22108531; 22124068; 22125454; 22126705; 22128229; 22154780; 22155307; 22160471; 22172512; 22173128; 22178859; 22183425; 22195044; 22227487; 22251538; 22266275; 22267217; 22275254; 22280559; 22285242; 22286731; 22311026; 22312160; 22340390; 22341060; 22344672; 22348697; 22349547; 22371121; 22382666; 22384041; 22384091; 22386525; 22389405; 22395218; 22414649; 22417897; 22425603; 22425785; 22449968; 22455686; 22455954; 22466287; 22467534; 22481167; 22487523; 22493010; 22498095; 22503230; 22513786; 22537218; 22540426; 22545750; 22547706; 22568934; 22569251; 22580886; 22596214; 22621205; 22621214; 22629474; 22629855; 22649552; 22673037; 22708826; 22710193; 22714811; 22727020; 22738689; 22739237; 22750393; 22759516; 22763042; 22763186; 22764136; 22768033; 22791816; 22795101; 22795647; 22796164; 22796220; 22796605; 22804923; 22805115; 22808497; 22811570; 22815289; 22818022; 22818222; 22822059; 22829602; 22829643; 22869038; 22878044; 22884582; 22884587; 22894561; 22898394; 22902304; 22904187; 22909148; 22911481; 22923190; 22937208; 22946471; 22947907; 22951596; 22955577; 22960943; 22995155; 22997256; 23006543; 23009887; 23013363; 23018032; 23020284; 23029154; 23052182; 23062767; 23065753; 23079713; 23105097; 23110185; 23169178; 23181791; 23184659; 23192617; 23195019; 23195574; 23199001; 23208827; 23209292; 23209411; 23209664; 23209696; 23210983; 23215648; 23215728; 23216199; 23217179; 23220433; 23226210; 23226468; 23229544; 23233369; 23237500; 23239492; 23241110; 23264411; 23269671; 23276701; 23313749; 23315075; 23317890; 23322904; 23323013; 23328087; 23328930; 23331079; 23349093; 23375040; 23383347; 23386602; 23391392; 23406266; 23417678; 23421536; 23425136; 23437386; 23452206; 23457635; 23459183; 23460134; 23460908; 23472661; 23484124; 23500159; 23508571; 23509682; 23531221; 23536554; 23546865; 23554905; 23555186; 23564444; 23571448; 23592003; 23592910; 23592922; 23610862; 23630220; 23633957; 23643268; 23650922; 23651237; 23654353; 23656735; 23657597; 23659674; 23660804; 23666803; 23680697; 23689297; 23702978; 23704929; 23717664; 23723976; 23726808; 23728092; 23737648; 23740952; 23747396; 23762029; 23773024; 23784458; 23793845; 23821953; 23822621; 23839215; 23840644; 23841472; 23884315; 23884363; 23892591; 23911403; 23927441; 23935506; 23936458; 23963575; 24022484; 24025329; 24035972; 24046015; 24078775; 24081990; 24146121; 24186874; 24265545; 24275344; 24313836; 24314919; 24338609; 24552038; 24611340 interleukin 1, beta Ensembl:ENSG00000125538 HGNC:5992 HPRD:00985 MIM:147720 Vega:OTTHUMG00000131344 IL1B Bin Zhao, Yue Liu, Oliver He IL-3 MCGF MULTI-CSF WEB: http://www.ncbi.nlm.nih.gov/gene IL3 interleukin 3 3562 5q31.1 20140409 9606 5 protein-coding Official from a nomenclature committee GO_0005125 (EC: IEA); GO_0005135 (EC: TAS, PMID: 2544122); GO_0005576 (EC: TAS); GO_0005615 (EC: ISS); GO_0006955 (EC: IEA); GO_0007267 (EC: TAS, PMID: 3497400); GO_0007399 (EC: TAS, PMID: 9736740); GO_0008083 (EC: IEA); GO_0008284 (EC: ISS); GO_0035162 (EC: IDA); GO_0042523 (EC: IDA, PMID: 9722506); GO_0045740 (EC: IDA, PMID: 9722506); GO_0050731 (EC: ISS) PMID: 1833064; 2268499; 2544122; 3127463; 3489530; 3497400; 3497843; 7642615; 7957082; 8018916; 8516290; 8649415; 8676386; 9030599; 9113989; 9209414; 9278420; 9551928; 9629242; 9659156; 9722506; 9736740; 10477722; 10677502; 11179015; 11399510; 11486081; 11700046; 11714768; 11763346; 11861295; 11994280; 12002675; 12055233; 12089333; 12093816; 12135758; 12165512; 12423306; 12477932; 12612065; 12759409; 12855588; 12884288; 12943658; 14551608; 14564341; 14615378; 14628073; 14675189; 14755254; 15060062; 15372022; 15372320; 15489334; 15576295; 15585837; 15878977; 15988318; 16785501; 17179997; 17207965; 17273755; 17362254; 17507237; 17541278; 17624239; 17703412; 18633131; 18676680; 18692472; 18768389; 18804346; 18826654; 18829683; 19074885; 19131452; 19158269; 19170196; 19201898; 19247692; 19258923; 19262575; 19529981; 19578876; 19625176; 19692168; 19730683; 19829692; 19845895; 19913121; 20147630; 20210668; 20237496; 20332709; 20381581; 20424473; 20452482; 20453000; 20472554; 20503287; 20516062; 20628086; 20673868; 20738848; 20800603; 20964623; 21071541; 21102463; 21168724; 21224257; 21262803; 21506110; 21643009; 22321809; 22412388; 22515947; 23024272; 23128233; 23226269; 23726808 interleukin 3 Ensembl:ENSG00000164399 HGNC:6011 HPRD:00987 MIM:147740 Vega:OTTHUMG00000059640 IL3 Bin Zhao, Yue Liu, Oliver He BCGF-1 BCGF1 BSF-1 BSF1 IL-4 WEB: http://www.ncbi.nlm.nih.gov/gene IL4 interleukin 4 3565 5q31.1 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0002227 (EC: IEA); GO_0002296 (EC: IEA); GO_0002674 (EC: IEA); GO_0002677 (EC: IEA); GO_0005125 (EC: IEA); GO_0005136 (EC: TAS, PMID: 11418631); GO_0005515 (EC: IPI, PMID: 10219247); GO_0005615 (EC: TAS, PMID: 11418631); GO_0006935 (EC: TAS, PMID: 10725748); GO_0006955 (EC: TAS, PMID: 3016727); GO_0006968 (EC: TAS, PMID: 10725748); GO_0007565 (EC: IEA); GO_0007584 (EC: IEA); GO_0008083 (EC: NAS, PMID: 11418631); GO_0008203 (EC: ISS, PMID: 11971948); GO_0009897 (EC: IEA); GO_0010155 (EC: IEA); GO_0014070 (EC: IEA); GO_0030183 (EC: TAS, PMID: 11418631); GO_0030890 (EC: ISS); GO_0031296 (EC: IEA); GO_0032733 (EC: IEA); GO_0032736 (EC: IDA, PMID: 19346497); GO_0034097 (EC: IEA); GO_0035745 (EC: IDA); GO_0042092 (EC: TAS, PMID: 11676128); GO_0042102 (EC: ISS); GO_0042104 (EC: IEA); GO_0042325 (EC: ISS); GO_0042493 (EC: IEA); GO_0042523 (EC: IEA); GO_0042832 (EC: IEA); GO_0043031 (EC: IEA); GO_0043066 (EC: ISS); GO_0045019 (EC: IEA); GO_0045064 (EC: IEA); GO_0045080 (EC: IEA); GO_0045189 (EC: TAS, PMID: 11967989); GO_0045191 (EC: TAS, PMID: 11418631); GO_0045348 (EC: ISS); GO_0045471 (EC: IEA); GO_0045582 (EC: IDA); GO_0045671 (EC: ISS); GO_0045892 (EC: IDA, PMID: 18579517); GO_0045893 (EC: IDA, PMID: 18579517); GO_0045944 (EC: ISS); GO_0048295 (EC: ISS); GO_0048304 (EC: ISS); GO_0050776 (EC: ISS); GO_0051091 (EC: IEA); GO_0071288 (EC: IEA); GO_0097028 (EC: IDA); GO_0097192 (EC: IEA); GO_2000320 (EC: IEA); GO_2001237 (EC: IEA) PMID: 1197194; 1346976; 1400355; 1511746; 1567880; 1567881; 1569578; 1609277; 1932028; 1946344; 1993171; 2535858; 3016727; 3257560; 7523014; 7589092; 7664036; 7695626; 7806280; 7963560; 8151703; 8266078; 8516290; 8602263; 8603435; 8609418; 8764000; 9113989; 9130521; 9130652; 9334723; 9799097; 9856950; 10219247; 10438901; 10473513; 10623799; 10710213; 10714547; 10725748; 10753117; 10853974; 11023480; 11035134; 11122213; 11149986; 11167377; 11233912; 11258628; 11258696; 11294568; 11298547; 11315919; 11316066; 11316069; 11320251; 11350513; 11396683; 11418631; 11466338; 11496248; 11502824; 11528525; 11587989; 11676128; 11678851; 11704810; 11728464; 11777980; 11786020; 11811777; 11841848; 11842291; 11872954; 11877044; 11881490; 11886168; 11897522; 11897999; 11907068; 11920312; 11922633; 11930331; 11950517; 11953141; 11960309; 11967989; 11968047; 11971948; 11980568; 11994288; 12020266; 12030894; 12039414; 12063527; 12066847; 12072494; 12082592; 12089714; 12102661; 12105273; 12107748; 12115161; 12121273; 12124654; 12133437; 12144536; 12161424; 12162874; 12165514; 12207324; 12220533; 12358844; 12363051; 12366695; 12368275; 12402189; 12420205; 12426308; 12435565; 12441140; 12442007; 12470598; 12477932; 12479817; 12504082; 12508140; 12508786; 12509382; 12513914; 12515722; 12517954; 12525574; 12542496; 12552499; 12574355; 12578333; 12587822; 12595908; 12600829; 12613995; 12626590; 12660931; 12663328; 12667657; 12687213; 12687247; 12689929; 12694433; 12700447; 12715242; 12738651; 12748907; 12753568; 12813360; 12851716; 12877559; 12884288; 12897746; 12900808; 12902508; 12911786; 12940513; 12944981; 12973929; 14499500; 14503851; 14522096; 14523823; 14530362; 14551608; 14561191; 14568946; 14583474; 14610476; 14634065; 14634100; 14652008; 14654080; 14675394; 14681304; 14688371; 14692664; 14693849; 14697238; 14697936; 14725568; 14729510; 14746805; 14764715; 14767810; 14983029; 14986816; 15001290; 15004182; 15007352; 15013759; 15014952; 15021309; 15041089; 15042002; 15051937; 15057902; 15063762; 15084933; 15086621; 15087090; 15100288; 15122773; 15123681; 15128803; 15163899; 15166131; 15170937; 15177147; 15178889; 15187156; 15191519; 15210741; 15213252; 15215692; 15241348; 15274656; 15292002; 15297269; 15298559; 15322832; 15361128; 15367434; 15373917; 15474066; 15489334; 15501397; 15527169; 15528258; 15563083; 15570643; 15591113; 15592292; 15596681; 15627726; 15644127; 15660235; 15660293; 15661875; 15676220; 15678501; 15679809; 15687724; 15695802; 15713213; 15714203; 15723707; 15733644; 15755291; 15778356; 15811521; 15816837; 15825027; 15869882; 15883744; 15885323; 15900570; 15900573; 15904474; 15919378; 15932621; 15941525; 15951665; 15969687; 15970635; 16001979; 16002690; 16004996; 16034134; 16043936; 16044136; 16046318; 16053729; 16083175; 16083600; 16091861; 16100774; 16164695; 16166103; 16184405; 16190985; 16193177; 16195814; 16215326; 16230423; 16232344; 16249002; 16289646; 16301860; 16313303; 16313681; 16315031; 16334248; 16343431; 16375755; 16380445; 16387595; 16388492; 16403098; 16427155; 16429138; 16429733; 16449530; 16461126; 16466711; 16487180; 16492782; 16511411; 16520888; 16522370; 16544245; 16547227; 16547693; 16551465; 16573560; 16574063; 16596275; 16601843; 16640778; 16681592; 16690518; 16702372; 16707627; 16720107; 16722389; 16750991; 16750993; 16759385; 16810739; 16864907; 16867043; 16877367; 16914241; 16916659; 16929824; 16930576; 16931887; 16938461; 16950634; 16973957; 16987060; 17006724; 17014622; 17015714; 17015735; 17063753; 17097641; 17117487; 17121586; 17133536; 17141086; 17143971; 17148075; 17151125; 17151939; 17152005; 17159260; 17177148; 17203290; 17207024; 17208210; 17209513; 17213232; 17222831; 17237413; 17257312; 17284225; 17291854; 17295710; 17299718; 17303794; 17303923; 17309781; 17311314; 17327605; 17355643; 17369174; 17371990; 17379175; 17388919; 17389011; 17389870; 17405833; 17420820; 17428692; 17433443; 17444864; 17451413; 17454884; 17460561; 17523428; 17524861; 17530998; 17536219; 17540990; 17541280; 17548690; 17563406; 17566759; 17576577; 17623648; 17627763; 17631734; 17640324; 17640674; 17644317; 17653830; 17655693; 17656331; 17662651; 17678726; 17703412; 17714919; 17851828; 17855802; 17882904; 17889143; 17908769; 17914408; 17916404; 17916900; 17937745; 17938902; 17961771; 17968425; 18008330; 18031948; 18042256; 18056382; 18058260; 18064451; 18088017; 18156980; 18165865; 18174230; 18179754; 18179773; 18202702; 18204280; 18206261; 18210751; 18211631; 18230112; 18239807; 18243101; 18251702; 18263811; 18273035; 18273643; 18276105; 18286287; 18294957; 18295676; 18310157; 18322173; 18342537; 18351434; 18371377; 18385759; 18389618; 18394346; 18396027; 18403443; 18410779; 18418228; 18422436; 18425216; 18433468; 18439079; 18441098; 18448485; 18454680; 18455629; 18476609; 18485518; 18497474; 18522869; 18533937; 18538381; 18547691; 18558283; 18566561; 18568448; 18568476; 18574615; 18579517; 18593330; 18596736; 18597704; 18599603; 18610831; 18610832; 18614592; 18624944; 18625055; 18626468; 18628242; 18629290; 18632425; 18633131; 18635180; 18636124; 18641314; 18651887; 18662263; 18674658; 18676680; 18676870; 18682601; 18688110; 18694328; 18696265; 18708672; 18716132; 18776133; 18781131; 18818748; 18834248; 18924208; 18927306; 18931892; 18936436; 18941246; 18955794; 18971287; 18971305; 18974110; 18974840; 19008611; 19013323; 19019335; 19028820; 19050632; 19058298; 19058839; 19066394; 19074885; 19116009; 19117745; 19122650; 19126646; 19129082; 19131452; 19131662; 19141349; 19164348; 19168731; 19169254; 19170196; 19185507; 19190772; 19193442; 19200845; 19222422; 19247692; 19249119; 19251840; 19254294; 19258923; 19261373; 19262574; 19263529; 19264973; 19275586; 19279357; 19332120; 19332998; 19336370; 19346497; 19347053; 19351467; 19370405; 19372547; 19375306; 19382262; 19385959; 19408823; 19409508; 19419769; 19421745; 19426601; 19437232; 19470040; 19479237; 19495883; 19497039; 19505916; 19508433; 19515749; 19521787; 19527514; 19536153; 19541591; 19544559; 19544973; 19552791; 19555572; 19559392; 19566553; 19573080; 19575932; 19578876; 19586918; 19586939; 19594368; 19621989; 19625176; 19657367; 19682920; 19683555; 19692168; 19698128; 19699526; 19706316; 19707465; 19718656; 19718824; 19721012; 19726720; 19735490; 19753334; 19762488; 19772762; 19773279; 19773451; 19799628; 19804407; 19811408; 19817957; 19818512; 19835477; 19840389; 19845895; 19857574; 19860911; 19862939; 19878651; 19882211; 19892918; 19910025; 19913121; 19915002; 19933216; 19938203; 19948975; 19959237; 20003246; 20010912; 20012528; 20016407; 20027321; 20030788; 20039421; 20049266; 20053586; 20056178; 20059579; 20082482; 20093796; 20100010; 20112007; 20121760; 20128416; 20139223; 20140262; 20145925; 20147633; 20177758; 20184663; 20192866; 20213229; 20217044; 20219689; 20222161; 20237496; 20299965; 20304823; 20305143; 20332709; 20349326; 20349753; 20364398; 20367137; 20394509; 20395963; 20403914; 20406299; 20413987; 20416077; 20418110; 20424473; 20442634; 20444155; 20452482; 20453000; 20459687; 20485362; 20503287; 20506498; 20517665; 20524005; 20525402; 20530519; 20533927; 20536507; 20565368; 20568250; 20580039; 20603037; 20603050; 20618516; 20620947; 20628086; 20644561; 20673868; 20703737; 20711808; 20713631; 20716621; 20719954; 20723894; 20726231; 20736038; 20808855; 20811626; 20814620; 20839488; 20852371; 20859068; 20880001; 20921925; 20942272; 20970781; 20980261; 21048327; 21054877; 21061265; 21067483; 21071541; 21085635; 21086908; 21106245; 21106524; 21111725; 21127885; 21191414; 21195738; 21198753; 21211660; 21268015; 21270410; 21276216; 21323696; 21354455; 21460743; 21471214; 21478113; 21501388; 21611195; 21636115; 21640045; 21644211; 21645924; 21646796; 21658970; 21690322; 21713407; 21729106; 21749213; 21755390; 21771210; 21788379; 21799768; 21819409; 21846818; 21857939; 21890374; 21900165; 21913997; 21966389; 21989417; 22045834; 22053598; 22087298; 22092872; 22104567; 22142023; 22143036; 22156341; 22157213; 22170601; 22174091; 22214155; 22226971; 22227092; 22249152; 22358381; 22365405; 22366824; 22387551; 22406175; 22441356; 22484241; 22484276; 22512783; 22521249; 22528336; 22538865; 22574929; 22583827; 22594992; 22615205; 22652416; 22675249; 22705603; 22805022; 22805115; 22824342; 22875803; 22884982; 22892939; 22921153; 22942430; 22986179; 22992805; 22997428; 23070918; 23087426; 23107766; 23110190; 23124025; 23128233; 23185315; 23222300; 23234779; 23245479; 23259293; 23276701; 23306429; 23333893; 23334651; 23376457; 23394902; 23398789; 23454622; 23511027; 23527200; 23527710; 23559861; 23572437; 23576103; 23591975; 23644020; 23651591; 23654077; 23668806; 23685257; 23694808; 23756167; 23756192; 23766027; 23768103; 23797532; 23831512; 23844087; 23883285; 23913957; 23923066; 23924473; 23935100; 23936398; 23958647; 23964553; 23983153; 24406619; 24510574 interleukin 4 Ensembl:ENSG00000113520 HGNC:6014 HPRD:00989 MIM:147780 Vega:OTTHUMG00000059724 IL4 Bin Zhao, Yue Liu, Oliver He CD124 IL-4RA IL4RA WEB: http://www.ncbi.nlm.nih.gov/gene IL4R interleukin 4 receptor 3566 582J2.1 16p12.1-p11.2 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0002532 (EC: IEA); GO_0004913 (EC: TAS, PMID: 2307934); GO_0005057 (EC: TAS, PMID: 2307934); GO_0005515 (EC: IPI, PMID: 10219247); GO_0005615 (EC: IEA); GO_0005887 (EC: TAS, PMID: 2307934); GO_0006955 (EC: TAS, PMID: 2307934); GO_0007165 (EC: TAS, PMID: 2307934); GO_0030728 (EC: IEA); GO_0035556 (EC: TAS, PMID: 2307934); GO_0035771 (EC: TAS, PMID: 2307934); GO_0042127 (EC: IEA); GO_0042832 (EC: IEA); GO_0043032 (EC: IEA); GO_0043235 (EC: IDA); GO_0043560 (EC: RCA, PMID: 19641626); GO_0043627 (EC: IEA); GO_0045626 (EC: IEA); GO_0045630 (EC: IEA); GO_0090197 (EC: IEA) PMID: 1617647; 1679753; 2114443; 2278997; 2307934; 7518439; 7538655; 7721895; 7775445; 8101483; 8124718; 8125298; 8222329; 8266076; 8266078; 8599766; 8609418; 8624803; 8804422; 8816495; 8891114; 8910586; 8916957; 8954948; 9070874; 9190938; 9392697; 9515586; 9545332; 9620765; 9651359; 9670964; 9697832; 9761767; 10201973; 10219247; 10233717; 10341317; 10358772; 10369419; 10390422; 10421786; 10486269; 10493829; 10590262; 10652211; 10677312; 10809862; 10856136; 11035134; 11164908; 11233912; 11285129; 11354638; 11491529; 11513543; 11528525; 11544427; 11678851; 11709756; 11714803; 11773030; 11786020; 11801567; 11811777; 11922633; 11991671; 12020266; 12047364; 12047365; 12082592; 12100043; 12115161; 12133952; 12133990; 12171893; 12207328; 12242343; 12401728; 12420205; 12422339; 12442007; 12454749; 12459556; 12477932; 12508140; 12558814; 12594065; 12743452; 12748907; 12753568; 12871855; 12897746; 12900808; 12940513; 12960323; 12973929; 14523823; 14615367; 14745651; 14984008; 15005726; 15007345; 15007352; 15021309; 15057902; 15122773; 15161635; 15170937; 15194285; 15298559; 15356556; 15361128; 15367225; 15479272; 15497451; 15521376; 15526032; 15564773; 15566952; 15660293; 15661890; 15712015; 15733644; 15737301; 15842262; 15969687; 15981567; 16024651; 16046318; 16100774; 16169070; 16184405; 16189667; 16226465; 16264039; 16280132; 16313303; 16313681; 16344560; 16387595; 16403098; 16503977; 16538488; 16551465; 16600026; 16613701; 16625214; 16640778; 16646030; 16681592; 16699452; 16750991; 16757160; 16842617; 16867043; 16914241; 16917945; 16938461; 16950281; 16961803; 17001290; 17006724; 17045041; 17083349; 17091279; 17115186; 17121586; 17143971; 17152005; 17170387; 17179726; 17201240; 17209513; 17257312; 17258448; 17284225; 17291854; 17303794; 17315188; 17362266; 17420820; 17444864; 17523428; 17536219; 17548690; 17586032; 17600229; 17627763; 17688234; 17703412; 17714919; 17823973; 17889143; 17900677; 17901851; 17988330; 18006935; 18031948; 18095154; 18179773; 18243101; 18263811; 18389618; 18425216; 18433792; 18448485; 18538381; 18547691; 18576348; 18610831; 18610832; 18625055; 18628242; 18632425; 18633131; 18636124; 18674658; 18676680; 18691306; 18715339; 18773331; 18774776; 18781131; 18809513; 18813073; 18818748; 18849614; 18927306; 18931892; 18936436; 18957266; 18974840; 19011907; 19019335; 19028820; 19074885; 19109239; 19117745; 19131662; 19170196; 19258923; 19263529; 19264973; 19279357; 19332120; 19382262; 19408823; 19414811; 19420105; 19421745; 19447482; 19470040; 19479237; 19505916; 19508433; 19515749; 19527514; 19531027; 19544559; 19548368; 19555572; 19559392; 19573080; 19590686; 19594368; 19625176; 19641626; 19657898; 19674346; 19683555; 19692168; 19729601; 19739012; 19773279; 19773451; 19783684; 19819209; 19860911; 19862939; 19863607; 19913121; 19956098; 20002627; 20040389; 20072140; 20085599; 20128416; 20140262; 20163933; 20176658; 20213229; 20219689; 20237496; 20298583; 20299965; 20378664; 20394509; 20416077; 20417488; 20424473; 20444266; 20452482; 20453000; 20459687; 20484924; 20503287; 20517665; 20536507; 20568250; 20603037; 20603050; 20628086; 20654748; 20673868; 20703737; 20716621; 20729386; 20811626; 21054877; 21061265; 21070662; 21071541; 21211370; 21251883; 21362618; 21489615; 21497535; 21536546; 21729106; 21733492; 21734400; 21906983; 21913997; 21918367; 22045834; 22059556; 22075330; 22087298; 22098734; 22119518; 22170601; 22261806; 22317767; 22355322; 22369735; 22376040; 22441356; 22484276; 22541248; 22633285; 22705603; 22764749; 22891178; 22902050; 22997428; 23066418; 23217179; 23376457; 23383283; 23395224; 23480403; 23525950; 23527710; 23543769; 23663500; 23784081; 23817569; 23883285; 23924473; 23979976; 23983153; 24251647; 24510574 interleukin 4 receptor Ensembl:ENSG00000077238 HGNC:6015 HPRD:00990 MIM:147781 Vega:OTTHUMG00000097015 IL4R Bin Zhao, Yue Liu, Oliver He BSF2 HGF HSF IFNB2 IL-6 WEB: http://www.ncbi.nlm.nih.gov/gene IL6 interleukin 6 3569 7p21 20140409 9606 7 protein-coding Official from a nomenclature committee GO_0001781 (EC: IDA, PMID: 7595060); GO_0002384 (EC: IDA, PMID: 2444978); GO_0002384 (EC: TAS, PMID: 12832423); GO_0002446 (EC: IC, PMID: 16034137); GO_0002548 (EC: IC, PMID: 10510402); GO_0002675 (EC: IDA, PMID: 2444978); GO_0002690 (EC: IC, PMID: 16034137); GO_0005125 (EC: IDA, PMID: 3023045); GO_0005125 (EC: NAS, PMID: 10443688); GO_0005138 (EC: IPI, PMID: 12829785); GO_0005138 (EC: IPI, Qualifier: contributes_to, PMID: 12829785); GO_0005138 (EC: NAS, PMID: 1883960); GO_0005515 (EC: IPI, PMID: 11238858); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 10443688); GO_0005896 (EC: IDA, PMID: 12829785); GO_0006469 (EC: IEA); GO_0006953 (EC: TAS, PMID: 12832423); GO_0006954 (EC: IDA, PMID: 10443688); GO_0006959 (EC: IC, PMID: 3491322); GO_0007568 (EC: IEA); GO_0008083 (EC: IDA, PMID: 12643274); GO_0008284 (EC: IDA, PMID: 2261637); GO_0008284 (EC: IMP, PMID: 18719127); GO_0008285 (EC: IEA); GO_0008360 (EC: IEA); GO_0009408 (EC: IEA); GO_0009409 (EC: IEA); GO_0009612 (EC: IEA); GO_0009897 (EC: IEA); GO_0010574 (EC: IDA, PMID: 8557680); GO_0010888 (EC: NAS, PMID: 16464856); GO_0016049 (EC: IEA); GO_0019221 (EC: IDA, PMID: 12643274); GO_0030168 (EC: TAS, PMID: 7831669); GO_0031000 (EC: IEA); GO_0031018 (EC: ISS, PMID: 18719127); GO_0031175 (EC: IMP, PMID: 3264880); GO_0031667 (EC: IEA); GO_0032494 (EC: IEP, PMID: 16034137); GO_0032496 (EC: IEA); GO_0032722 (EC: IDA, PMID: 10510402); GO_0032722 (EC: IMP, PMID: 16034137); GO_0032755 (EC: IDA, PMID: 10510402); GO_0032868 (EC: IEA); GO_0032966 (EC: IDA, PMID: 12419823); GO_0033138 (EC: IDA, PMID: 7508917); GO_0033160 (EC: IEA); GO_0042102 (EC: IDA, PMID: 3130269); GO_0042493 (EC: IEA); GO_0042517 (EC: IDA, PMID: 12643274); GO_0042832 (EC: IEA); GO_0043065 (EC: IDA, PMID: 9949178); GO_0043066 (EC: IDA, PMID: 7595060); GO_0043154 (EC: IEA); GO_0043200 (EC: IEA); GO_0043410 (EC: IDA, PMID: 12419823); GO_0045079 (EC: ISS); GO_0045188 (EC: IEA); GO_0045429 (EC: IEA); GO_0045454 (EC: IEA); GO_0045599 (EC: NAS, PMID: 16464856); GO_0045630 (EC: IEA); GO_0045666 (EC: IEA); GO_0045669 (EC: TAS, PMID: 12372336); GO_0045721 (EC: IEA); GO_0045727 (EC: IDA, PMID: 16732314); GO_0045740 (EC: IEA); GO_0045765 (EC: IC, PMID: 8557680); GO_0045893 (EC: IDA, PMID: 7749983); GO_0045944 (EC: IDA, PMID: 17324931); GO_0046427 (EC: IDA, PMID: 12419823); GO_0046677 (EC: IEA); GO_0046716 (EC: IEA); GO_0046849 (EC: IEA); GO_0046888 (EC: IEA); GO_0048635 (EC: IEA); GO_0048661 (EC: IDA, PMID: 10510402); GO_0050679 (EC: IEA); GO_0050710 (EC: IEA); GO_0050731 (EC: IDA, PMID: 7508917); GO_0050829 (EC: IEP, PMID: 16034137); GO_0050830 (EC: IEP, PMID: 16034137); GO_0050871 (EC: IDA, PMID: 3491322); GO_0051024 (EC: IDA, PMID: 3491322); GO_0051091 (EC: IDA, PMID: 7749983); GO_0051092 (EC: IDA, Qualifier: NOT, PMID: 12419823); GO_0051384 (EC: IDA, PMID: 10443688); GO_0051592 (EC: IEA); GO_0051602 (EC: IEA); GO_0051607 (EC: IDA, PMID: 3023045); GO_0051897 (EC: IEA); GO_0051971 (EC: IEA); GO_0060445 (EC: IEA); GO_0060664 (EC: IEA); GO_0070091 (EC: ISS, PMID: 18719127); GO_0070102 (EC: IDA, PMID: 12552091); GO_0070301 (EC: IDA, PMID: 19168699); GO_0070374 (EC: IEA); GO_0072540 (EC: ISS); GO_1901215 (EC: IEA); GO_2000366 (EC: IC, PMID: 17324931); GO_2000676 (EC: TAS, PMID: 18719127) PMID: 1113021; 1291290; 1346976; 1610348; 1656094; 1883960; 1918997; 2037043; 2261637; 2444978; 2472117; 2610854; 2680567; 2788034; 2789513; 2829354; 2906047; 3023045; 3130269; 3264880; 3266463; 3279116; 3294161; 3320204; 3491322; 3500852; 3538015; 3758081; 7494249; 7508917; 7511078; 7511596; 7523444; 7526541; 7536422; 7553888; 7595060; 7656270; 7693046; 7704970; 7749983; 7803268; 7815507; 7831669; 7851440; 7986583; 8018916; 8086129; 8113688; 8179923; 8190832; 8206884; 8247028; 8510564; 8555185; 8557680; 8764000; 8806809; 8938574; 9094636; 9108403; 9118960; 9159484; 9169458; 9225992; 9378998; 9658081; 9671211; 9792375; 9927325; 9949178; 10358063; 10388525; 10415019; 10443688; 10510402; 10657672; 10671302; 10775602; 10777583; 10925276; 10964543; 11028446; 11040178; 11054276; 11072134; 11072751; 11116068; 11145851; 11167813; 11196676; 11196678; 11199329; 11204808; 11212160; 11224491; 11233912; 11238858; 11266856; 11266927; 11266928; 11267084; 11282548; 11312376; 11315919; 11316066; 11342474; 11354638; 11355017; 11371414; 11391238; 11397324; 11404167; 11448119; 11485024; 11500818; 11517385; 11520812; 11544427; 11544434; 11544437; 11557672; 11574109; 11640949; 11687509; 11689614; 11692078; 11703956; 11713964; 11716039; 11728144; 11733366; 11751408; 11758653; 11774563; 11777983; 11781191; 11788581; 11792588; 11794009; 11801594; 11818668; 11820460; 11847482; 11849463; 11853279; 11855786; 11858187; 11862386; 11884027; 11884029; 11884401; 11884403; 11889177; 11895465; 11902285; 11906646; 11914754; 11918227; 11919083; 11922913; 11949822; 11950481; 11950697; 11956023; 11959895; 11960393; 11961304; 11966578; 11981433; 11983287; 11984595; 11988246; 11988625; 11990931; 11992567; 12000745; 12012622; 12027404; 12031914; 12032172; 12036196; 12038454; 12047360; 12050565; 12051396; 12067898; 12070032; 12080442; 12082590; 12082592; 12086705; 12089333; 12089714; 12091348; 12095061; 12096924; 12096927; 12107724; 12110411; 12114287; 12117737; 12117921; 12117953; 12121679; 12133353; 12140751; 12149213; 12150965; 12151314; 12164325; 12165085; 12176919; 12183057; 12185451; 12187073; 12198224; 12200114; 12201209; 12202945; 12214260; 12215823; 12217290; 12218157; 12219016; 12220549; 12226829; 12232842; 12235153; 12239630; 12240899; 12297113; 12297725; 12352619; 12359225; 12359431; 12370346; 12370360; 12370503; 12371985; 12372336; 12382118; 12383455; 12391243; 12392859; 12393446; 12393542; 12393699; 12394188; 12396456; 12412787; 12413693; 12419823; 12430875; 12431817; 12445202; 12445803; 12451269; 12453469; 12468916; 12472176; 12477932; 12482836; 12483530; 12491092; 12493411; 12495721; 12507818; 12509497; 12517591; 12517814; 12519862; 12526950; 12540635; 12552091; 12553555; 12554901; 12558814; 12559950; 12560330; 12560873; 12571160; 12574335; 12574550; 12584029; 12585340; 12589429; 12590978; 12591385; 12592380; 12594059; 12595908; 12606524; 12615367; 12618859; 12626585; 12629515; 12633940; 12634650; 12637697; 12643274; 12647840; 12651071; 12653788; 12657090; 12660820; 12660878; 12663465; 12664314; 12668153; 12668157; 12681965; 12690205; 12694213; 12709682; 12713584; 12714254; 12714267; 12716337; 12719374; 12720537; 12727482; 12727794; 12727841; 12727948; 12727959; 12736743; 12737276; 12742994; 12743452; 12745542; 12746914; 12748876; 12754410; 12756345; 12757654; 12760309; 12768442; 12770686; 12771987; 12789531; 12790760; 12792728; 12794182; 12796383; 12799618; 12802423; 12810629; 12811627; 12815949; 12818128; 12819039; 12828754; 12829659; 12829785; 12830005; 12832117; 12832326; 12832423; 12839942; 12840146; 12843190; 12843357; 12846758; 12850808; 12853948; 12857677; 12857678; 12870175; 12871882; 12876073; 12883476; 12888915; 12897342; 12900415; 12901869; 12919773; 12923493; 12926107; 12928051; 12928784; 12932839; 12934185; 12937023; 12938195; 12940515; 12944981; 12945076; 12952969; 12958150; 12960275; 12960348; 12967650; 12969979; 12970232; 13678786; 14508181; 14508221; 14512079; 14514772; 14521945; 14522096; 14523169; 14523823; 14532843; 14557255; 14557477; 14557872; 14563376; 14566095; 14566255; 14568951; 14582815; 14585094; 14586325; 14604894; 14607690; 14625191; 14633738; 14634582; 14634584; 14643032; 14644408; 14654926; 14656692; 14657427; 14675394; 14676217; 14680981; 14684705; 14688371; 14691340; 14709647; 14711458; 14718574; 14733913; 14735187; 14739370; 14739540; 14748439; 14756669; 14872501; 14967376; 14969768; 14970177; 14981536; 14990346; 14997289; 15001458; 15005726; 15005841; 15015143; 15016829; 15019283; 15021309; 15025214; 15028733; 15030461; 15034082; 15036420; 15041164; 15041717; 15041721; 15044662; 15050298; 15051507; 15057902; 15070705; 15070960; 15072962; 15075299; 15083368; 15086488; 15100309; 15100312; 15104679; 15105457; 15118287; 15120188; 15120189; 15121272; 15135265; 15135368; 15152368; 15153787; 15154666; 15158360; 15166129; 15167972; 15170937; 15171792; 15172007; 15172469; 15180970; 15180973; 15189946; 15193488; 15193763; 15194285; 15194822; 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21518763; 21520044; 21520052; 21526159; 21527852; 21530175; 21535154; 21535317; 21536090; 21540553; 21546767; 21547256; 21559372; 21562768; 21565862; 21586579; 21591973; 21592994; 21594636; 21595886; 21600698; 21611774; 21619709; 21619877; 21620438; 21621860; 21623995; 21626471; 21632260; 21639625; 21640816; 21645137; 21656745; 21658317; 21664423; 21668366; 21681687; 21684758; 21689404; 21697747; 21700657; 21702700; 21708999; 21709158; 21712995; 21714933; 21716327; 21729562; 21740541; 21752694; 21757719; 21757746; 21762913; 21767605; 21769475; 21771210; 21773651; 21776298; 21778161; 21795706; 21801267; 21802729; 21811961; 21811986; 21813290; 21833041; 21833517; 21843047; 21845403; 21845872; 21845926; 21851175; 21854184; 21858117; 21863560; 21870243; 21875833; 21876502; 21880216; 21881374; 21881585; 21886773; 21889771; 21898505; 21898706; 21898993; 21900165; 21902578; 21911244; 21912394; 21913828; 21919032; 21921047; 21923250; 21925926; 21929671; 21931651; 21933586; 21935443; 21938724; 21952248; 21953462; 21954831; 21957581; 21959016; 21961943; 21965736; 21966220; 21967801; 21976712; 21977994; 21982018; 21983734; 21984125; 21989726; 21995322; 21995333; 21996739; 22000300; 22004976; 22010855; 22012292; 22015309; 22015454; 22018243; 22019000; 22019436; 22021612; 22023383; 22024650; 22025890; 22027148; 22030312; 22030478; 22035595; 22046434; 22048241; 22052387; 22053612; 22055894; 22068677; 22068875; 22070971; 22072054; 22072539; 22075267; 22078452; 22082020; 22084439; 22105366; 22107760; 22113576; 22113815; 22115178; 22117975; 22119941; 22122521; 22132241; 22133543; 22135153; 22140472; 22150003; 22155094; 22156348; 22158046; 22159219; 22171160; 22171994; 22174866; 22180363; 22187702; 22192353; 22194466; 22196489; 22203929; 22203932; 22205395; 22209080; 22228719; 22229879; 22230324; 22234866; 22242132; 22243796; 22252554; 22261689; 22265273; 22272811; 22289556; 22296202; 22296277; 22301094; 22301607; 22303451; 22304944; 22306454; 22324945; 22330622; 22334615; 22337942; 22349830; 22350281; 22357713; 22362117; 22364742; 22365967; 22366404; 22367386; 22369948; 22382666; 22385075; 22386866; 22386961; 22387051; 22389450; 22403134; 22407921; 22410655; 22417709; 22417897; 22420891; 22421411; 22422499; 22425021; 22426116; 22426177; 22426431; 22427231; 22427564; 22427681; 22428468; 22431998; 22434029; 22436412; 22441019; 22445549; 22452603; 22452847; 22457277; 22457856; 22459738; 22462419; 22466975; 22468900; 22473756; 22475215; 22479352; 22481167; 22486303; 22491065; 22496403; 22496888; 22503230; 22507133; 22508062; 22513191; 22516897; 22521547; 22531363; 22531887; 22532634; 22532637; 22539302; 22552350; 22553973; 22554382; 22562290; 22563871; 22565057; 22569438; 22571276; 22575724; 22577092; 22579111; 22579472; 22580582; 22580886; 22583691; 22586157; 22592039; 22595649; 22615316; 22616715; 22617158; 22617683; 22634718; 22642105; 22644871; 22647735; 22648519; 22667128; 22672862; 22673037; 22677780; 22677919; 22681487; 22686131; 22687336; 22688021; 22692705; 22695063; 22696056; 22698992; 22701584; 22710869; 22711534; 22711691; 22714907; 22726456; 22728071; 22734797; 22739041; 22739042; 22740511; 22743617; 22752116; 22753384; 22761193; 22761857; 22763042; 22763101; 22769440; 22773460; 22782910; 22796263; 22808178; 22810465; 22814248; 22814515; 22818022; 22819248; 22819326; 22819759; 22836752; 22843654; 22843899; 22849850; 22867712; 22869038; 22872134; 22883217; 22883518; 22894740; 22895491; 22904305; 22906998; 22908985; 22921280; 22923190; 22923236; 22924939; 22927445; 22931953; 22948743; 22956742; 22964303; 22968454; 22976070; 22977256; 22977658; 22982189; 22983646; 22984080; 22984233; 22986484; 22990627; 23009764; 23013217; 23013513; 23018032; 23019398; 23022409; 23025692; 23027872; 23027890; 23034889; 23036532; 23038213; 23043537; 23044206; 23052480; 23052692; 23056300; 23058014; 23058031; 23062767; 23065424; 23071313; 23073774; 23078005; 23078984; 23086036; 23087143; 23088295; 23092922; 23097096; 23100065; 23116190; 23117246; 23118848; 23124416; 23124693; 23136553; 23136554; 23136556; 23142265; 23154434; 23158132; 23159256; 23159283; 23161179; 23166328; 23168096; 23168996; 23175672; 23177780; 23178494; 23180271; 23185547; 23190106; 23195133; 23197841; 23198942; 23204162; 23206733; 23207068; 23219526; 23224211; 23225885; 23227240; 23232337; 23233117; 23236659; 23242654; 23246692; 23250823; 23251686; 23255681; 23257175; 23262029; 23265967; 23269580; 23272057; 23276493; 23276701; 23281720; 23289913; 23298711; 23300019; 23303450; 23311694; 23320781; 23322593; 23322904; 23326472; 23332218; 23336844; 23344094; 23347173; 23348396; 23349093; 23349310; 23350010; 23357299; 23357300; 23363979; 23364322; 23369187; 23371411; 23375410; 23377045; 23378274; 23378460; 23380741; 23389820; 23392112; 23399848; 23408619; 23411129; 23415255; 23421536; 23423626; 23425215; 23428306; 23441314; 23444260; 23461479; 23461851; 23470607; 23470916; 23478175; 23480455; 23484124; 23487197; 23489698; 23490068; 23490413; 23498057; 23505291; 23506572; 23509207; 23510010; 23510983; 23517877; 23524623; 23525184; 23536722; 23538947; 23555579; 23555719; 23559389; 23561329; 23564454; 23564789; 23567762; 23569034; 23582441; 23582716; 23591770; 23593036; 23593346; 23601055; 23616277; 23617681; 23619188; 23622344; 23625043; 23630220; 23632023; 23633489; 23633491; 23637318; 23637926; 23638863; 23639700; 23648010; 23651237; 23654074; 23657600; 23658720; 23665320; 23666170; 23674845; 23701120; 23735697; 23737648; 23743311; 23746176; 23748363; 23756867; 23761639; 23762476; 23762858; 23766379; 23770252; 23774701; 23776669; 23777202; 23784949; 23785756; 23791019; 23792529; 23807226; 23815102; 23819403; 23821953; 23828679; 23832741; 23844163; 23884764; 23889749; 23893709; 23910616; 23913484; 23921153; 23928667; 23929842; 23933386; 23936495; 23953057; 23953866; 23954444; 23954871; 23968978; 23969696; 24032723; 24043651; 24044580; 24051035; 24077340; 24078775; 24114793; 24120137; 24136650; 24152848; 24186266; 24200066; 24243972; 24265545; 24294778; 24299316; 24308236; 24314919; 24340926; 24409674; 24434384; 24547612 interleukin 6 Ensembl:ENSG00000136244 HGNC:6018 HPRD:00970 MIM:147620 Vega:OTTHUMG00000023178 IL6 Bin Zhao, Yue Liu, Oliver He CD126 IL-6R-1 IL-6RA IL6Q IL6RA IL6RQ gp80 WEB: http://www.ncbi.nlm.nih.gov/gene IL6R interleukin 6 receptor 3570 1q21 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0002384 (EC: TAS, PMID: 12832423); GO_0002446 (EC: IC, PMID: 16034137); GO_0002548 (EC: IC, PMID: 10510402); GO_0002690 (EC: IC, PMID: 16034137); GO_0002690 (EC: TAS, PMID: 15100312); GO_0004897 (EC: IMP, Qualifier: contributes_to, PMID: 12643274); GO_0004915 (EC: IDA, Qualifier: contributes_to, PMID: 2261637); GO_0005138 (EC: IPI, Qualifier: contributes_to, PMID: 12829785); GO_0005515 (EC: IPI, PMID: 11238858); GO_0005576 (EC: IDA, PMID: 12748171); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 12419823); GO_0005886 (EC: TAS); GO_0005896 (EC: IDA, PMID: 12829785); GO_0006953 (EC: TAS, PMID: 12832423); GO_0008284 (EC: IDA, PMID: 2261637); GO_0008284 (EC: IMP, PMID: 18719127); GO_0009986 (EC: IEA); GO_0010536 (EC: IDA, PMID: 12419823); GO_0016323 (EC: IEA); GO_0016324 (EC: IDA, PMID: 16034137); GO_0019221 (EC: IDA, PMID: 2261637); GO_0019899 (EC: IPI, PMID: 12748171); GO_0019981 (EC: IPI, PMID: 12829785); GO_0031018 (EC: IC, PMID: 18719127); GO_0031018 (EC: IMP, PMID: 18719127); GO_0032717 (EC: IEP, PMID: 16034137); GO_0032722 (EC: IDA, PMID: 10510402); GO_0032755 (EC: IDA, PMID: 10510402); GO_0032966 (EC: IDA, PMID: 12419823); GO_0034097 (EC: IDA, PMID: 2261637); GO_0042517 (EC: IMP, PMID: 12643274); GO_0042803 (EC: IPI, PMID: 12633863); GO_0043410 (EC: IDA, PMID: 12419823); GO_0045669 (EC: TAS, PMID: 12372336); GO_0048661 (EC: IDA, PMID: 10510402); GO_0050731 (EC: IDA, PMID: 11884403); GO_0050829 (EC: IEP, PMID: 16034137); GO_0050830 (EC: IEP, PMID: 16034137); GO_0051092 (EC: IDA, Qualifier: NOT, PMID: 12419823); GO_0070102 (EC: IMP, PMID: 12643274); GO_0070119 (EC: IPI, PMID: 12643274); GO_0070120 (EC: IMP, PMID: 12643274); GO_0097191 (EC: TAS, PMID: 15100312) PMID: 1281789; 1381187; 1872801; 1889804; 2112585; 2157217; 2261637; 2529343; 2788034; 3136546; 8056053; 8125298; 8265649; 8428753; 8450224; 8467812; 8889549; 9169421; 9927325; 10066782; 10462375; 10510402; 10777583; 10785334; 10982829; 11017875; 11238858; 11884403; 12002769; 12008038; 12079407; 12372336; 12412787; 12414855; 12419823; 12445803; 12461182; 12472176; 12477932; 12553038; 12553555; 12574959; 12633863; 12643274; 12748171; 12748876; 12789531; 12829785; 12832423; 12857602; 12917504; 14557255; 14592826; 14718574; 15041717; 15063602; 15100312; 15166129; 15213442; 15284182; 15297310; 15306846; 15456942; 15489334; 15561970; 15562008; 15579373; 15625895; 15641051; 15816827; 15837717; 15857508; 15895091; 16034137; 16127269; 16270750; 16372246; 16557588; 16710414; 16731080; 16794539; 16817825; 16899024; 16912152; 16973585; 17151125; 17160948; 17310346; 17313958; 17346257; 17357077; 17519976; 17570254; 17619842; 17652155; 17671508; 17703412; 17898129; 17903307; 17908769; 17984249; 18065760; 18276608; 18320358; 18439548; 18464913; 18490707; 18508242; 18538149; 18543249; 18676680; 18719127; 18781131; 18784373; 18818748; 18852330; 18853133; 18971377; 18980999; 19019335; 19026125; 19088723; 19124510; 19170196; 19258923; 19277666; 19280716; 19336475; 19396608; 19406470; 19420002; 19422646; 19453261; 19495883; 19503017; 19505916; 19527514; 19567438; 19573080; 19625176; 19633828; 19665805; 19671870; 19692168; 19713205; 19733878; 19773279; 19773451; 19790045; 19877065; 19913121; 19914334; 19926672; 19966016; 20017315; 20026129; 20031577; 20083667; 20140262; 20145925; 20157327; 20159251; 20186139; 20197062; 20237496; 20379614; 20438838; 20452482; 20453000; 20463041; 20484876; 20503287; 20551110; 20568250; 20599261; 20600579; 20628086; 20661738; 20673868; 20698883; 20727736; 20800603; 20811626; 20823887; 20839491; 20856253; 20951753; 20974296; 21159831; 21173340; 21196890; 21220034; 21229891; 21255427; 21282511; 21295508; 21300955; 21401300; 21490132; 21496483; 21515913; 21700295; 21748280; 21813064; 21835044; 21846873; 21851175; 21879314; 21907864; 21968316; 21981268; 21989726; 22072558; 22079540; 22128229; 22133618; 22209080; 22295972; 22319020; 22421339; 22449275; 22552503; 22554704; 22642608; 22742541; 22761857; 22911828; 22984080; 23073775; 23078005; 23094986; 23242610; 23375120; 23428306; 23564454; 23582566; 23582716; 23593036; 23648090; 23658720; 23677452; 23902164; 23935104; 23969696; 24032723; 24152848 interleukin 6 receptor Ensembl:ENSG00000160712 HGNC:6019 HPRD:01000 MIM:147880 Vega:OTTHUMG00000036073 IL6R Bin Zhao, Yue Liu, Oliver He CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 WEB: http://www.ncbi.nlm.nih.gov/gene IL8 interleukin 8 3576 4q13-q21 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0001525 (EC: TAS, PMID: 11483765); GO_0002237 (EC: IDA, PMID: 19912257); GO_0005153 (EC: IPI, PMID: 1840701); GO_0005515 (EC: IPI, PMID: 10880251); GO_0005576 (EC: TAS); GO_0005615 (EC: IEA); GO_0006928 (EC: TAS, PMID: 10820279); GO_0006935 (EC: TAS, PMID: 12782716); GO_0006954 (EC: TAS, PMID: 11483765); GO_0006955 (EC: IEA); GO_0006987 (EC: TAS); GO_0007050 (EC: IDA, PMID: 11564821); GO_0007165 (EC: TAS, PMID: 10820279); GO_0007186 (EC: TAS, PMID: 8381837); GO_0008009 (EC: TAS, PMID: 12782716); GO_0008285 (EC: TAS, PMID: 9551928); GO_0019722 (EC: TAS, PMID: 11877327); GO_0030155 (EC: IDA, PMID: 2007144); GO_0030593 (EC: IGI, PMID: 11564821); GO_0030968 (EC: TAS); GO_0031623 (EC: IDA, PMID: 10734056); GO_0034976 (EC: IDA); GO_0035556 (EC: IDA, PMID: 10734056); GO_0042119 (EC: TAS, PMID: 11483765); GO_0044267 (EC: TAS); GO_0044344 (EC: IEP, PMID: 9407497); GO_0045091 (EC: IDA, PMID: 11483765); GO_0045744 (EC: IDA, PMID: 10734056); GO_0048566 (EC: IEP); GO_0050930 (EC: IGI, PMID: 11564821); GO_0071222 (EC: IDA, PMID: 19912257); GO_0071347 (EC: IEP, PMID: 9407497); GO_0071356 (EC: IEP, PMID: 9407497); GO_0090023 (EC: TAS, PMID: 1699135) PMID: 1281554; 1391327; 1639201; 1673289; 1699135; 1840701; 1895676; 1988949; 2005614; 2007144; 2145175; 2170450; 2182630; 2184886; 2200751; 2212672; 2456256; 2523801; 2555418; 2648135; 2648569; 2655583; 2659722; 2663993; 2664463; 2681204; 2834384; 2953813; 3057503; 3223947; 3260265; 3279957; 3322281; 3480540; 7673721; 7695626; 8077676; 8081002; 8381837; 8626516; 8631339; 8662698; 8663179; 8702798; 8995686; 9141135; 9323208; 9363947; 9378998; 9407497; 9464567; 9510190; 9551928; 9659156; 9828130; 9921412; 10343098; 10361232; 10368283; 10376933; 10491366; 10620615; 10707023; 10734056; 10764593; 10775602; 10820279; 10823949; 10880251; 10881932; 10929056; 10982368; 10985244; 10985253; 11023497; 11069235; 11083887; 11160671; 11226151; 11328384; 11483765; 11509627; 11564821; 11756416; 11784713; 11814358; 11854210; 11855786; 11868823; 11876744; 11877327; 11884401; 11884459; 11888846; 11896938; 11910304; 11911801; 11940655; 11950481; 11956621; 11960393; 11964077; 11966578; 11973337; 11978786; 11989790; 11999552; 12021366; 12027404; 12033786; 12034575; 12039947; 12055238; 12055326; 12056817; 12060853; 12067976; 12081586; 12089333; 12090473; 12091490; 12093676; 12096924; 12096927; 12100025; 12101072; 12115500; 12117737; 12117926; 12117969; 12117995; 12123753; 12126643; 12133438; 12139952; 12149127; 12150710; 12151316; 12151344; 12163591; 12164325; 12165085; 12169092; 12169272; 12186702; 12186913; 12187073; 12195386; 12223528; 12225945; 12239630; 12359770; 12364441; 12366401; 12370346; 12382118; 12384994; 12388718; 12388959; 12391099; 12393171; 12410798; 12415593; 12453441; 12477932; 12480084; 12485855; 12496258; 12502445; 12513912; 12520365; 12524080; 12529421; 12530093; 12533683; 12543081; 12547728; 12548717; 12565901; 12573991; 12576442; 12584113; 12586630; 12594001; 12594058; 12615831; 12626597; 12628493; 12632066; 12633940; 12634636; 12637525; 12646250; 12653788; 12654635; 12654834; 12660426; 12662377; 12702497; 12707271; 12720537; 12727029; 12729795; 12738388; 12744776; 12748056; 12748173; 12777373; 12782302; 12782716; 12792476; 12797546; 12802400; 12818188; 12820969; 12839933; 12839942; 12849706; 12850808; 12855659; 12857601; 12870115; 12871882; 12876073; 12898436; 12898448; 12901801; 12902511; 12909591; 12919697; 12933891; 12952969; 12960242; 13129857; 14500465; 14500470; 14500479; 14530367; 14550286; 14578856; 14604894; 14623984; 14625302; 14630611; 14634582; 14634584; 14641180; 14645117; 14657869; 14669337; 14672330; 14675394; 14676125; 14688120; 14711052; 14714557; 14718619; 14725568; 14729508; 14730209; 14756945; 14767470; 14977935; 15001458; 15021975; 15022458; 15039334; 15047831; 15057743; 15063730; 15069060; 15072962; 15077296; 15079071; 15085176; 15096327; 15102084; 15120188; 15133028; 15143062; 15146413; 15152368; 15158775; 15169673; 15178568; 15178703; 15181190; 15194816; 15196572; 15203561; 15203565; 15208657; 15208668; 15209388; 15214047; 15218164; 15220553; 15222686; 15265021; 15271933; 15273081; 15280021; 15280372; 15292066; 15297389; 15300588; 15302608; 15321994; 15321998; 15331599; 15337758; 15342208; 15356171; 15356575; 15358661; 15364108; 15379213; 15385484; 15453805; 15454487; 15469436; 15481145; 15489227; 15489334; 15494311; 15496610; 15498828; 15514971; 15521010; 15528384; 15529362; 15531763; 15534087; 15541716; 15542429; 15556942; 15564333; 15569594; 15579374; 15579377; 15579481; 15583145; 15585560; 15585673; 15591054; 15598788; 15607204; 15607368; 15609321; 15613411; 15615716; 15627645; 15630185; 15630732; 15641067; 15650393; 15650394; 15652404; 15652492; 15659384; 15661856; 15664665; 15667946; 15679580; 15701651; 15708897; 15710978; 15731050; 15746434; 15760459; 15760676; 15784717; 15803062; 15805227; 15828019; 15831558; 15845475; 15845476; 15845864; 15854776; 15862344; 15866212; 15894298; 15897801; 15902922; 15914533; 15917409; 15945132; 15962221; 15972644; 15976103; 15976326; 15979992; 15987860; 15989802; 16004996; 16007706; 16029496; 16038881; 16038986; 16039610; 16052590; 16085794; 16088182; 16096323; 16098041; 16098254; 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24273918; 24284797; 24313836; 24344010 interleukin 8 Ensembl:ENSG00000169429 HGNC:6025 HPRD:00909 MIM:146930 Vega:OTTHUMG00000151316 IL8 Bin Zhao, Yue Liu, Oliver He C-C C-C-CKR-1 CD128 CD181 CDw128a CKR-1 CMKAR1 IL8R1 IL8RA IL8RBA WEB: http://www.ncbi.nlm.nih.gov/gene CXCR1 chemokine (C-X-C motif) receptor 1 3577 2q35 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0002407 (EC: TAS, PMID: 16621978); GO_0004918 (EC: IDA, PMID: 10734056); GO_0004930 (EC: TAS, PMID: 8381837); GO_0004950 (EC: TAS, PMID: 1840701); GO_0005886 (EC: TAS); GO_0006935 (EC: TAS, PMID: 10725748); GO_0006954 (EC: TAS, PMID: 10725748); GO_0007166 (EC: IDA, PMID: 10734056); GO_0007186 (EC: TAS, PMID: 8381837); GO_0016020 (EC: TAS, PMID: 10725748); GO_0016021 (EC: IEA); GO_0019959 (EC: IPI, PMID: 11564821); GO_0031623 (EC: IDA, PMID: 10734056); GO_0038112 (EC: IDA, PMID: 10734056); GO_0070098 (EC: TAS, PMID: 1840701) PMID: 1303245; 1379593; 1427896; 1840701; 2834384; 7527448; 7650389; 7829970; 7868904; 7929358; 8077663; 8195702; 8316840; 8381837; 8384312; 8486366; 8500355; 8662698; 8702798; 8903513; 9260277; 9692902; 9843397; 10368283; 10570306; 10593335; 10725748; 10734056; 10843722; 11007922; 11196695; 11397869; 11564821; 12002274; 12055238; 12077146; 12239185; 12442335; 12477932; 12535747; 12576754; 12628493; 12651900; 12870115; 14688334; 14713106; 15028716; 15133028; 15265017; 15292066; 15454487; 15489334; 15545821; 15556942; 15579377; 15598788; 15618253; 15641067; 15764156; 15772681; 15793866; 15815621; 15902300; 15946947; 16098254; 16205979; 16406804; 16411061; 16500343; 16621978; 16679868; 16897191; 16950632; 16987681; 17026468; 17169533; 17204468; 17207897; 17295203; 17296422; 17360650; 17361014; 17596666; 17604950; 17672867; 17786197; 17876799; 17996233; 18025257; 18059279; 18240029; 18577758; 18667484; 18676680; 18676870; 18818748; 19012493; 19019335; 19118103; 19151925; 19401689; 19423540; 19505916; 19527514; 19573080; 19585580; 19625176; 19634663; 19681642; 19692168; 19735481; 19773279; 19773451; 19890050; 19913121; 20016196; 20016852; 20044480; 20089160; 20237496; 20406964; 20438785; 20452482; 20453000; 20628086; 20630874; 20811626; 21036625; 21042230; 21048114; 21297633; 21323370; 21452410; 21555225; 21749879; 21915051; 21988832; 21989491; 22019593; 22024025; 22051099; 22076427; 22088968; 22152684; 22171941; 22174157; 22242662; 22262769; 22325052; 22482416; 22489883; 22563025; 22626766; 22763101; 22904195; 22936990; 23086146; 23128233; 23349885; 23396733; 23470693; 23525041; 23904157; 23912333; 24161763 chemokine (C-X-C motif) receptor 1 Ensembl:ENSG00000163464 HGNC:6026 HPRD:00908 MIM:146929 Vega:OTTHUMG00000133108 CXCR1 Bin Zhao, Yue Liu, Oliver He CD182 CDw128b CMKAR2 IL8R2 IL8RA IL8RB WEB: http://www.ncbi.nlm.nih.gov/gene CXCR2 chemokine (C-X-C motif) receptor 2 3579 2q35 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0002407 (EC: TAS, PMID: 16621978); GO_0002438 (EC: IEA); GO_0004871 (EC: IDA, PMID: 10438939); GO_0004918 (EC: IDA, PMID: 10820279); GO_0005515 (EC: IPI); GO_0005622 (EC: IDA, PMID: 10878382); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 10438939); GO_0006935 (EC: IDA, PMID: 10725748); GO_0006954 (EC: TAS, PMID: 9725262); GO_0006968 (EC: IDA, PMID: 10725748); GO_0007165 (EC: IDA, PMID: 10820279); GO_0007166 (EC: IDA, PMID: 10734056); GO_0007200 (EC: IDA, PMID: 10438939); GO_0007204 (EC: IEA); GO_0008284 (EC: IDA, PMID: 10438939); GO_0009986 (EC: IDA, PMID: 10878382); GO_0010666 (EC: IEA); GO_0016020 (EC: IDA, PMID: 10725748); GO_0016494 (EC: IDA, PMID: 10878382); GO_0019959 (EC: IPI, PMID: 1840701); GO_0030593 (EC: IDA, PMID: 10820279); GO_0030901 (EC: IEA); GO_0031623 (EC: IDA, PMID: 10734056); GO_0033030 (EC: IEA); GO_0038112 (EC: IDA, PMID: 10820279); GO_0042119 (EC: IDA, PMID: 10878382); GO_0042629 (EC: IDA, PMID: 9725262); GO_0043117 (EC: IEA); GO_0045766 (EC: IEA); GO_0070098 (EC: IDA, PMID: 10878382); GO_0072173 (EC: IEA); GO_0090023 (EC: IEA) PMID: 1303245; 1379593; 1427896; 1840701; 1891716; 2834384; 7512557; 7829970; 7929358; 8036519; 8194768; 8195702; 8294449; 8316840; 8384312; 8550564; 8626516; 8662698; 8702798; 8940121; 9058825; 9079638; 9260277; 9464567; 9651375; 9692902; 9725262; 9843397; 10438939; 10593335; 10688807; 10725748; 10734056; 10820279; 10878382; 10881932; 10943863; 11007922; 11023990; 11138777; 11170396; 11196695; 11278485; 11397869; 11435493; 11524231; 11751889; 11818437; 12164325; 12176324; 12239185; 12442335; 12453441; 12477932; 12496258; 12606476; 12620646; 12628493; 12633567; 12870115; 12888558; 12975484; 14713106; 14967163; 15004234; 15028716; 15063762; 15265017; 15358660; 15364949; 15452121; 15454487; 15479720; 15489334; 15545821; 15598788; 15618253; 15626158; 15630732; 15772681; 15793866; 15946947; 16086366; 16098254; 16260092; 16272353; 16344560; 16406804; 16411061; 16621978; 16679868; 16702372; 16793206; 16897191; 16987681; 16990258; 17003486; 17142783; 17204468; 17272812; 17295203; 17360650; 17435771; 17604950; 17630697; 17672867; 17703412; 17709521; 17939034; 17949231; 17996233; 18025257; 18199703; 18208820; 18240029; 18244953; 18292390; 18307412; 18462836; 18555777; 18577758; 18633131; 18676870; 18755694; 18780829; 18852457; 19010874; 19012493; 19026125; 19035451; 19057948; 19067586; 19118103; 19147552; 19151925; 19155217; 19170196; 19258923; 19401689; 19423540; 19435808; 19435811; 19549892; 19573080; 19585580; 19634663; 19750480; 19773279; 19887480; 19890050; 19904283; 19913121; 20005738; 20016196; 20016852; 20018298; 20044480; 20056178; 20070156; 20089160; 20140262; 20237496; 20406964; 20419088; 20429924; 20438785; 20452482; 20453000; 20468071; 20485444; 20503287; 20505188; 20519647; 20540789; 20568250; 20580690; 20628086; 20630874; 20635912; 20673868; 20802378; 21036625; 21042230; 21106938; 21297633; 21343381; 21441140; 21555225; 21670971; 21749879; 21876773; 21915051; 21948388; 21989491; 22076427; 22088968; 22117410; 22152684; 22171941; 22203670; 22231733; 22242662; 22274915; 22325052; 22389383; 22482416; 22617157; 22626766; 22763041; 22763101; 22850671; 22885102; 22893608; 22904195; 22986777; 23023221; 23029099; 23128233; 23204236; 23293110; 23389772; 23403077; 23470693; 23479735; 23548249; 23615182; 23758411; 23912333; 23972657; 24161763 chemokine (C-X-C motif) receptor 2 Ensembl:ENSG00000180871 HGNC:6027 HPRD:00907 MIM:146928 Vega:OTTHUMG00000133107 CXCR2 Bin Zhao, Yue Liu, Oliver He CSIF GVHDS IL-10 IL10A TGIF WEB: http://www.ncbi.nlm.nih.gov/gene IL10 interleukin 10 3586 RP11-262N9.1 1q31-q32 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0002237 (EC: IDA, PMID: 17449476); GO_0002740 (EC: IDA, PMID: 10443688); GO_0002875 (EC: IEA); GO_0002904 (EC: IDA, PMID: 9184696); GO_0005125 (EC: NAS, PMID: 10443688); GO_0005141 (EC: NAS, PMID: 1847510); GO_0005615 (EC: IDA, PMID: 10443688); GO_0006954 (EC: IDA, PMID: 10443688); GO_0007253 (EC: NAS, PMID: 10975994); GO_0007267 (EC: IC, PMID: 1847510); GO_0008083 (EC: NAS, PMID: 1371884); GO_0010468 (EC: IDA, PMID: 9184696); GO_0014823 (EC: IEA); GO_0014854 (EC: IEA); GO_0030097 (EC: TAS, PMID: 11244051); GO_0030183 (EC: NAS, PMID: 8228801); GO_0030595 (EC: TAS, PMID: 9405662); GO_0030886 (EC: IEA); GO_0030889 (EC: IDA, PMID: 9184696); GO_0032689 (EC: IEA); GO_0032695 (EC: IEA); GO_0032715 (EC: IDA, PMID: 10443688); GO_0032720 (EC: IEA); GO_0032800 (EC: IDA, PMID: 10443688); GO_0032868 (EC: IEA); GO_0034465 (EC: IEA); GO_0042092 (EC: TAS, PMID: 11244051); GO_0042100 (EC: NAS, PMID: 8228801); GO_0042130 (EC: NAS, PMID: 14971032); GO_0042493 (EC: IEA); GO_0042536 (EC: IEA); GO_0042742 (EC: IEA); GO_0043066 (EC: NAS, PMID: 8312229); GO_0044130 (EC: IEA); GO_0045019 (EC: IEA); GO_0045191 (EC: NAS, PMID: 8228801); GO_0045347 (EC: TAS, PMID: 11244051); GO_0045348 (EC: IEA); GO_0045355 (EC: NAS, PMID: 9637497); GO_0045893 (EC: IDA, PMID: 7749983); GO_0045944 (EC: IEA); GO_0050715 (EC: IDA, PMID: 10443688); GO_0051045 (EC: IDA, PMID: 18383040); GO_0051091 (EC: IDA, PMID: 7749983); GO_0051384 (EC: IDA, PMID: 10443688); GO_0051930 (EC: IEA); GO_0060670 (EC: IEA); GO_0071222 (EC: NAS, PMID: 14971032); GO_0071392 (EC: IEA) PMID: 1121048; 1350294; 1371884; 1847510; 2173142; 7511078; 7527834; 7547951; 7553888; 7590988; 7591871; 7695626; 7749063; 7749983; 7759550; 7815507; 8037735; 8228801; 8248239; 8312229; 8364028; 8402911; 8499633; 8590020; 8764000; 8881045; 8897595; 8898665; 8910398; 9043871; 9096366; 9108403; 9143942; 9162098; 9184696; 9225992; 9234486; 9312047; 9334723; 9405662; 9463379; 9534962; 9637497; 9658081; 9689103; 9743208; 9788463; 10064624; 10089566; 10231374; 10443688; 10542212; 10714547; 10775602; 10807185; 10975994; 10985253; 11023480; 11023665; 11044099; 11087201; 11121048; 11137132; 11160847; 11163082; 11168433; 11192323; 11196656; 11196688; 11196718; 11212157; 11223972; 11230752; 11233912; 11238636; 11244051; 11260510; 11266927; 11266928; 11267084; 11271474; 11292301; 11294564; 11298547; 11307152; 11315919; 11316066; 11316069; 11354638; 11391238; 11404167; 11436536; 11441115; 11477472; 11478505; 11485736; 11493351; 11496247; 11517440; 11528523; 11544427; 11544434; 11544437; 11640949; 11689215; 11715070; 11717514; 11737614; 11740730; 11745479; 11758730; 11777537; 11792123; 11805149; 11820460; 11821159; 11828010; 11829538; 11833470; 11838849; 11852287; 11857058; 11869683; 11881827; 11883743; 11896938; 11906646; 11908705; 11919157; 11920312; 11922883; 11928840; 11929132; 11943322; 11952921; 11953141; 11953994; 11956022; 11960393; 11964134; 11964300; 11970958; 11986609; 11991675; 11994432; 12011375; 12020266; 12028020; 12039409; 12042661; 12047360; 12050565; 12060853; 12067976; 12069178; 12069391; 12078789; 12089333; 12089714; 12093676; 12095061; 12095128; 12097418; 12100571; 12100575; 12101075; 12104048; 12115622; 12117955; 12119553; 12121678; 12121679; 12124654; 12133353; 12133517; 12145682; 12151439; 12160736; 12164325; 12164877; 12165551; 12170266; 12189567; 12190181; 12197884; 12202153; 12203138; 12207099; 12207325; 12207353; 12209037; 12215823; 12219016; 12220553; 12220699; 12223518; 12232842; 12233881; 12239181; 12270545; 12370394; 12377950; 12389080; 12390476; 12392859; 12393426; 12393603; 12393699; 12394188; 12404162; 12420205; 12423294; 12438341; 12438348; 12438424; 12438965; 12444143; 12447749; 12451269; 12458048; 12477767; 12477932; 12486603; 12493739; 12495723; 12496396; 12496489; 12507818; 12509628; 12525572; 12526950; 12531774; 12534553; 12535204; 12538698; 12540792; 12544990; 12548511; 12554901; 12558814; 12578333; 12581488; 12590978; 12591385; 12594817; 12595905; 12595908; 12599058; 12609526; 12615834; 12616343; 12618859; 12626585; 12627487; 12631183; 12633940; 12640314; 12651071; 12654092; 12662377; 12663757; 12667161; 12668613; 12671741; 12676754; 12687213; 12687247; 12688341; 12700072; 12700599; 12705485; 12707018; 12709682; 12714267; 12714269; 12727335; 12727482; 12730860; 12738388; 12738467; 12743452; 12746253; 12746914; 12756345; 12761561; 12761564; 12765479; 12778475; 12782719; 12787424; 12788307; 12788980; 12791310; 12791313; 12791314; 12792880; 12799024; 12799207; 12802400; 12813360; 12818128; 12823999; 12824008; 12825869; 12826153; 12826369; 12828754; 12847677; 12847896; 12850811; 12851716; 12861049; 12864989; 12867583; 12909463; 12925485; 12926133; 12934185; 12938145; 12938195; 12940515; 12942209; 12944981; 12944983; 12945076; 12946990; 12959221; 12967650; 12971465; 13129651; 14512909; 14514772; 14522096; 14523823; 14550257; 14551598; 14562641; 14563376; 14566095; 14567558; 14572794; 14583474; 14585195; 14592815; 14597210; 14616291; 14625191; 14629328; 14630401; 14631168; 14638775; 14642153; 14646574; 14647192; 14657427; 14669219; 14675398; 14679088; 14682393; 14697748; 14697935; 14698136; 14701701; 14701704; 14722888; 14730222; 14742283; 14744383; 14746814; 14746878; 14748015; 14756669; 14872501; 14959851; 14969768; 14971032; 14978075; 14994383; 14999688; 15001471; 15007355; 15016829; 15021309; 15036247; 15039132; 15041164; 15042002; 15057267; 15057902; 15066699; 15070757; 15072702; 15078471; 15084933; 15085177; 15086488; 15100460; 15102771; 15104679; 15116066; 15120189; 15122773; 15122797; 15127646; 15129234; 15131577; 15135368; 15142213; 15144570; 15152368; 15155645; 15161508; 15170937; 15179129; 15180472; 15187110; 15188059; 15189946; 15191519; 15194284; 15194285; 15200436; 15200452; 15207246; 15212825; 15214940; 15221281; 15223609; 15223612; 15225432; 15235132; 15246967; 15247007; 15247172; 15265021; 15271933; 15288631; 15292002; 15292362; 15295621; 15304673; 15306847; 15316224; 15316663; 15325405; 15325406; 15340161; 15345120; 15345504; 15346339; 15351436; 15361124; 15361128; 15367225; 15368517; 15374585; 15381182; 15388260; 15452323; 15458467; 15462469; 15465816; 15466015; 15481145; 15485815; 15488737; 15497451; 15527169; 15530917; 15534100; 15547296; 15551142; 15561982; 15562761; 15566952; 15573087; 15579372; 15579481; 15581980; 15592292; 15596839; 15599305; 15599664; 15602175; 15603866; 15603899; 15607028; 15611648; 15621151; 15622443; 15643599; 15644127; 15650893; 15652446; 15659329; 15661939; 15663746; 15663966; 15674653; 15678510; 15682481; 15686588; 15690532; 15693804; 15694997; 15709194; 15711248; 15714121; 15718915; 15723707; 15728515; 15733644; 15747244; 15748779; 15749884; 15755291; 15761493; 15763337; 15772682; 15773449; 15780075; 15780879; 15784411; 15787640; 15800006; 15803357; 15809210; 15810889; 15811521; 15814696; 15814743; 15815688; 15815689; 15818327; 15837194; 15838798; 15841043; 15842590; 15843082; 15845862; 15848524; 15857508; 15863393; 15871134; 15884119; 15886526; 15894515; 15900488; 15901906; 15907845; 15910294; 15914210; 15915323; 15918171; 15919371; 15919456; 15925543; 15927351; 15927856; 15931634; 15932621; 15933064; 15933743; 15937090; 15940038; 15941525; 15951665; 15956545; 15964392; 15978325; 15979955; 15985167; 15990800; 15993715; 16008678; 16014616; 16024856; 16030091; 16030322; 16034145; 16038043; 16043753; 16043936; 16043989; 16051275; 16059673; 16076299; 16078336; 16083174; 16084491; 16091126; 16098562; 16100774; 16109775; 16114018; 16120761; 16122836; 16133175; 16148556; 16160188; 16162776; 16163478; 16164695; 16165702; 16171432; 16173237; 16182624; 16183136; 16184405; 16193177; 16202743; 16226734; 16230423; 16232344; 16243534; 16247433; 16249504; 16256199; 16259956; 16276011; 16279907; 16284379; 16287542; 16287924; 16305644; 16313808; 16323127; 16323614; 16331571; 16341266; 16343245; 16361810; 16362796; 16364177; 16375755; 16378074; 16378687; 16380445; 16389181; 16396704; 16403098; 16411061; 16412052; 16413199; 16424284; 16425360; 16429138; 16433832; 16435103; 16441483; 16449530; 16460885; 16461080; 16464746; 16481285; 16489646; 16493441; 16507146; 16522370; 16523426; 16525502; 16537004; 16537707; 16540751; 16547227; 16551363; 16566641; 16567828; 16570020; 16573560; 16573780; 16579847; 16584395; 16585075; 16600026; 16611358; 16618781; 16635219; 16638698; 16644716; 16672066; 16672072; 16672419; 16681592; 16690414; 16690518; 16698276; 16698426; 16699450; 16699452; 16702372; 16702858; 16707559; 16712948; 16720107; 16720211; 16722148; 16723241; 16730575; 16759385; 16762155; 16780675; 16781761; 16785496; 16803619; 16803995; 16803996; 16804000; 16807647; 16809636; 16815316; 16820326; 16820919; 16824070; 16824159; 16826368; 16842617; 16850164; 16859503; 16859504; 16861661; 16861684; 16863661; 16867043; 16872712; 16883528; 16889540; 16895750; 16905295; 16907941; 16908746; 16911685; 16920714; 16924108; 16930778; 16931134; 16933851; 16938461; 16940525; 16943796; 16945026; 16949747; 16959027; 16961803; 16962335; 16971956; 16973274; 16978071; 16984283; 16987066; 17003778; 17005410; 17006334; 17006724; 17015714; 17015751; 17041236; 17049666; 17051272; 17052299; 17052682; 17070109; 17083041; 17092253; 17097497; 17103073; 17107380; 17113632; 17122782; 17132891; 17133531; 17138053; 17138064; 17141301; 17145371; 17145373; 17152005; 17163451; 17173255; 17178344; 17178764; 17182240; 17188628; 17198275; 17202341; 17204399; 17207568; 17208210; 17209781; 17213232; 17215337; 17215862; 17220333; 17225142; 17230494; 17237407; 17237722; 17238853; 17241871; 17257312; 17261758; 17261759; 17263806; 17304105; 17307204; 17310845; 17314689; 17321603; 17321902; 17326156; 17331973; 17335372; 17336597; 17338374; 17351514; 17353161; 17355643; 17369174; 17373677; 17376198; 17380193; 17380888; 17388919; 17389013; 17389235; 17393023; 17407084; 17408400; 17412916; 17413867; 17420099; 17428673; 17431682; 17438520; 17444587; 17444864; 17448042; 17449476; 17454884; 17460178; 17463301; 17470530; 17483704; 17487426; 17490670; 17496310; 17498265; 17509455; 17510437; 17511783; 17522354; 17524861; 17530721; 17537769; 17543146; 17544514; 17544674; 17544800; 17546224; 17548183; 17552041; 17553352; 17559370; 17559576; 17565648; 17568575; 17572155; 17574964; 17576577; 17587429; 17587715; 17592300; 17597660; 17605296; 17607501; 17612762; 17617027; 17618436; 17627763; 17634568; 17640058; 17640324; 17645476; 17645589; 17652887; 17653830; 17654453; 17656331; 17665434; 17674321; 17678726; 17684137; 17686006; 17688234; 17689273; 17690160; 17690329; 17700165; 17703177; 17703412; 17704111; 17706223; 17711410; 17714919; 17716348; 17716608; 17717744; 17724799; 17761309; 17762971; 17763324; 17763336; 17804501; 17825889; 17845635; 17846855; 17869646; 17875118; 17875573; 17884957; 17889143; 17903648; 17908769; 17916230; 17917921; 17919702; 17923267; 17929139; 17932439; 17938902; 17945537; 17947295; 17960405; 17961177; 17965799; 17968299; 17974504; 17979488; 17980158; 17981284; 17983270; 17988266; 17990180; 17999153; 18023359; 18023521; 18024395; 18039196; 18041006; 18042256; 18049335; 18054497; 18056366; 18056971; 18057536; 18071035; 18071881; 18080762; 18086767; 18090276; 18093240; 18093541; 18093884; 18158121; 18163209; 18164040; 18165865; 18171291; 18173702; 18174230; 18174250; 18184461; 18191118; 18192685; 18199828; 18200504; 18201362; 18208460; 18212693; 18216090; 18218037; 18221542; 18230105; 18234565; 18234854; 18235016; 18239807; 18242340; 18249038; 18267346; 18271063; 18273643; 18283248; 18284424; 18286551; 18292506; 18299793; 18303205; 18304876; 18307517; 18310311; 18311435; 18312596; 18315435; 18318911; 18325328; 18337305; 18341210; 18347814; 18353715; 18361934; 18362084; 18362887; 18363812; 18366487; 18375254; 18382869; 18383040; 18383862; 18384906; 18387831; 18391721; 18391751; 18392953; 18393655; 18397303; 18400189; 18405249; 18408074; 18414898; 18416756; 18424735; 18424756; 18427872; 18430198; 18436572; 18436829; 18439592; 18440625; 18444945; 18447856; 18448485; 18456270; 18457043; 18479293; 18479302; 18485518; 18490728; 18490762; 18493769; 18502564; 18510721; 18512809; 18522869; 18523359; 18534084; 18538381; 18539537; 18541226; 18551071; 18554409; 18559596; 18560870; 18569989; 18576303; 18579697; 18582197; 18583979; 18589089; 18593434; 18597405; 18609361; 18612930; 18614592; 18616700; 18619701; 18627514; 18628242; 18628251; 18632425; 18633131; 18633332; 18633768; 18636124; 18638093; 18640487; 18641355; 18651178; 18665050; 18665932; 18668392; 18674658; 18676680; 18676870; 18680515; 18683035; 18687423; 18692180; 18703108; 18705845; 18707865; 18725394; 18753053; 18760861; 18781131; 18792803; 18793860; 18794066; 18796448; 18797896; 18798072; 18805892; 18815552; 18818748; 18819899; 18826950; 18832862; 18836448; 18843277; 18845324; 18923248; 18924213; 18930197; 18931463; 18936436; 18937577; 18945465; 18950592; 18952289; 18953879; 18956675; 18962896; 18972133; 18972297; 18974840; 18974842; 18976327; 18996999; 18997484; 18997828; 19001136; 19004675; 19005292; 19009622; 19011628; 19012493; 19013323; 19013788; 19019335; 19021042; 19026560; 19027043; 19028820; 19031431; 19034880; 19038787; 19039953; 19050632; 19055487; 19056482; 19058854; 19058987; 19064572; 19065724; 19066394; 19071030; 19074885; 19077731; 19082598; 19084429; 19086955; 19087313; 19089920; 19097982; 19099482; 19109192; 19110537; 19111610; 19117745; 19118909; 19124156; 19124506; 19126646; 19127455; 19131662; 19132772; 19145440; 19153889; 19157224; 19164257; 19170196; 19176318; 19183122; 19184348; 19196047; 19200845; 19201467; 19201880; 19208551; 19210299; 19210338; 19222424; 19225544; 19228651; 19237018; 19237638; 19238444; 19239428; 19244371; 19246943; 19247692; 19249119; 19258635; 19258923; 19259799; 19264973; 19267370; 19272082; 19272636; 19274101; 19275586; 19276283; 19279357; 19282863; 19284443; 19290853; 19295315; 19295440; 19295541; 19299022; 19300393; 19307576; 19308651; 19319950; 19321591; 19332120; 19334424; 19336263; 19336370; 19336475; 19337556; 19341387; 19347053; 19348329; 19349988; 19358670; 19365081; 19372622; 19375306; 19375805; 19376105; 19383027; 19383626; 19385959; 19386798; 19389111; 19401389; 19401395; 19401628; 19407822; 19408823; 19409109; 19412539; 19413695; 19415548; 19419334; 19420105; 19427781; 19430480; 19437115; 19437232; 19450147; 19458621; 19470040; 19474090; 19477525; 19478959; 19479237; 19480854; 19481774; 19481975; 19488421; 19495883; 19497711; 19501525; 19505916; 19505919; 19508433; 19527514; 19528258; 19534595; 19541591; 19543506; 19544559; 19552724; 19552919; 19555400; 19559392; 19561105; 19562463; 19565483; 19570392; 19573080; 19576194; 19578796; 19578817; 19579695; 19581835; 19585232; 19586841; 19591971; 19594368; 19596995; 19604093; 19608017; 19608431; 19614971; 19617629; 19620304; 19621425; 19621989; 19625176; 19625651; 19644155; 19652739; 19656776; 19658300; 19661010; 19661089; 19667950; 19669876; 19673019; 19683555; 19692168; 19692203; 19698128; 19698145; 19700159; 19700502; 19700864; 19706920; 19711225; 19733878; 19737632; 19738620; 19740314; 19744138; 19748989; 19753334; 19758163; 19758192; 19759281; 19760027; 19762082; 19762555; 19766898; 19771178; 19773279; 19773451; 19778488; 19779724; 19781301; 19782084; 19786281; 19796538; 19798061; 19802007; 19805095; 19811408; 19813110; 19817985; 19819209; 19821803; 19822020; 19823053; 19838195; 19852851; 19856416; 19860911; 19861958; 19882211; 19889024; 19889076; 19889475; 19890236; 19892918; 19895848; 19907653; 19908064; 19908237; 19912737; 19913121; 19915572; 19917162; 19934104; 19936625; 19938203; 19939284; 19948975; 19956635; 19957794; 19958312; 19996617; 19996656; 20001857; 20010527; 20012528; 20014019; 20015215; 20016407; 20016783; 20017308; 20018615; 20030788; 20032313; 20037209; 20042578; 20042580; 20044609; 20047977; 20051670; 20052801; 20059417; 20061995; 20070620; 20070836; 20072143; 20080912; 20082482; 20082647; 20083555; 20087644; 20087693; 20087947; 20089329; 20097948; 20102414; 20107186; 20138641; 20144201; 20145925; 20148913; 20150436; 20150742; 20163933; 20171114; 20176734; 20177758; 20178529; 20181890; 20184663; 20188863; 20189706; 20190550; 20191326; 20191386; 20195402; 20195716; 20196868; 20200511; 20202139; 20204402; 20207250; 20207982; 20213229; 20217044; 20227257; 20227772; 20228669; 20228798; 20228799; 20232770; 20233508; 20236506; 20236616; 20237496; 20299965; 20302034; 20305143; 20306684; 20335604; 20337945; 20339193; 20339966; 20349753; 20356901; 20359252; 20363151; 20367137; 20369436; 20370995; 20371920; 20378550; 20378664; 20381257; 20384861; 20385468; 20388088; 20388104; 20393813; 20395963; 20399512; 20404426; 20410487; 20413987; 20416077; 20418110; 20419805; 20421626; 20424473; 20424554; 20424918; 20430716; 20431935; 20438703; 20445748; 20447254; 20448110; 20452482; 20453000; 20454933; 20457266; 20459687; 20463618; 20470442; 20471133; 20472930; 20473875; 20477882; 20482524; 20484443; 20484876; 20485362; 20485444; 20486195; 20490277; 20490891; 20503287; 20509889; 20518833; 20518842; 20519163; 20523065; 20525402; 20527514; 20529592; 20530519; 20531015; 20536507; 20536548; 20551628; 20553628; 20558465; 20561040; 20564140; 20565774; 20567520; 20568250; 20570082; 20571871; 20576226; 20578820; 20587610; 20588103; 20588308; 20589076; 20591588; 20592893; 20595152; 20602615; 20603037; 20603050; 20617924; 20618176; 20622753; 20622878; 20622879; 20625422; 20628086; 20628373; 20638860; 20640364; 20644561; 20646924; 20650298; 20659236; 20661303; 20661604; 20662694; 20671651; 20673868; 20711808; 20714960; 20716621; 20720222; 20722024; 20723894; 20725607; 20732366; 20735825; 20737205; 20798845; 20804371; 20805562; 20807264; 20809522; 20809684; 20811626; 20825427; 20825636; 20830806; 20835611; 20838432; 20839488; 20860222; 20861424; 20863526; 20879862; 20880001; 20880267; 20880745; 20881642; 20883321; 20884746; 20889146; 20889800; 20922456; 20927126; 20934598; 20934961; 20942272; 20952070; 20953818; 20957732; 20970781; 20976276; 21030268; 21037509; 21040915; 21048327; 21052690; 21054877; 21055074; 21055733; 21057561; 21057730; 21061265; 21067483; 21067752; 21068755; 21076061; 21086908; 21088899; 21090240; 21098222; 21102463; 21107607; 21107665; 21123382; 21131395; 21135123; 21138342; 21160051; 21168854; 21183270; 21191065; 21205466; 21211963; 21215074; 21215285; 21216474; 21223691; 21227406; 21238445; 21239715; 21240493; 21254836; 21255795; 21267581; 21281983; 21297633; 21300911; 21303362; 21309719; 21314735; 21316985; 21317876; 21323660; 21328800; 21332458; 21339768; 21354456; 21357266; 21357402; 21358669; 21359250; 21372199; 21398611; 21398617; 21402594; 21406270; 21413929; 21424183; 21426411; 21439624; 21440743; 21455338; 21463487; 21466366; 21467695; 21468030; 21468579; 21478113; 21481602; 21508509; 21518800; 21519827; 21526166; 21527907; 21532858; 21549291; 21553228; 21558138; 21560494; 21567173; 21595995; 21609779; 21621860; 21624746; 21626471; 21641950; 21642542; 21658228; 21658363; 21669226; 21688665; 21689404; 21699407; 21721376; 21724486; 21725623; 21729106; 21730023; 21744325; 21756510; 21757655; 21764596; 21767236; 21777343; 21779975; 21786452; 21791113; 21792878; 21808111; 21812905; 21816135; 21829393; 21830424; 21839042; 21858117; 21861711; 21862302; 21863566; 21863628; 21869490; 21873118; 21876975; 21878338; 21901441; 21902578; 21909800; 21910858; 21917128; 21918473; 21923667; 21925952; 21926547; 21931651; 21936714; 21940055; 21968303; 21972680; 21986577; 21998459; 22010076; 22019000; 22032897; 22033829; 22038351; 22048455; 22050548; 22057691; 22057973; 22058059; 22070668; 22075762; 22077544; 22079540; 22081333; 22082370; 22092594; 22095765; 22100578; 22105495; 22116520; 22122951; 22123389; 22129927; 22140263; 22140472; 22144535; 22156547; 22157213; 22158873; 22160576; 22168225; 22172723; 22174866; 22176654; 22182686; 22184725; 22187388; 22189417; 22189756; 22205204; 22205395; 22213066; 22219323; 22225835; 22235320; 22239992; 22263663; 22279662; 22287022; 22288916; 22298356; 22307790; 22311038; 22323454; 22325340; 22335769; 22347492; 22350281; 22356904; 22358381; 22366404; 22371646; 22378604; 22387064; 22390924; 22393278; 22410761; 22416256; 22424164; 22425021; 22425265; 22427230; 22436502; 22442690; 22445549; 22466287; 22475179; 22484198; 22484241; 22487811; 22494514; 22503116; 22507621; 22520513; 22529524; 22535664; 22537067; 22537751; 22544931; 22547702; 22547705; 22549091; 22556042; 22565155; 22566507; 22572643; 22575708; 22578382; 22580886; 22582500; 22586040; 22592039; 22592860; 22594912; 22595646; 22628023; 22634719; 22644143; 22653776; 22655468; 22664006; 22673037; 22677268; 22678905; 22681958; 22682876; 22685028; 22687336; 22698805; 22710869; 22711892; 22715992; 22732092; 22740130; 22749664; 22753934; 22753938; 22763734; 22768144; 22784413; 22788775; 22795294; 22796266; 22805022; 22812212; 22812241; 22818022; 22825546; 22835429; 22835835; 22848356; 22850906; 22851691; 22859398; 22859944; 22880107; 22886309; 22897390; 22902304; 22911481; 22924705; 22931953; 22932817; 22940633; 22966128; 22972930; 22981868; 22986179; 22989497; 23013217; 23013641; 23017230; 23020144; 23021880; 23027536; 23028907; 23029361; 23034167; 23046616; 23046617; 23053983; 23062006; 23062580; 23069299; 23071313; 23073467; 23075771; 23079832; 23086275; 23088578; 23094074; 23095823; 23096091; 23118878; 23125413; 23128233; 23143946; 23149083; 23152883; 23159283; 23166328; 23168096; 23185315; 23192326; 23207823; 23209731; 23210681; 23220432; 23225254; 23232337; 23235789; 23237063; 23237776; 23251077; 23265747; 23272193; 23273903; 23273955; 23276701; 23294711; 23299779; 23300021; 23300769; 23325892; 23326478; 23334981; 23335974; 23343479; 23349310; 23355741; 23357299; 23363891; 23376084; 23379624; 23380741; 23415626; 23416458; 23430974; 23432860; 23438682; 23444260; 23449984; 23450495; 23453286; 23460834; 23485354; 23485538; 23485736; 23488731; 23498167; 23525950; 23541976; 23544075; 23556339; 23562725; 23570798; 23574339; 23582441; 23583365; 23591975; 23595519; 23602200; 23602201; 23607333; 23613317; 23623844; 23638863; 23640160; 23640982; 23645090; 23654353; 23663047; 23663500; 23668806; 23679256; 23690289; 23711712; 23712703; 23716201; 23720844; 23723980; 23725154; 23725178; 23733877; 23743567; 23749933; 23752129; 23752604; 23762097; 23768819; 23772925; 23777202; 23797738; 23798430; 23814099; 23818986; 23834952; 23838435; 23846686; 23875023; 23880295; 23880623; 23886125; 23897063; 23898109; 23901045; 23910644; 23936042; 23990628; 24015034; 24042116; 24043893; 24067460; 24077340; 24130510; 24174668; 24216477; 24327156; 24340926; 24379064 interleukin 10 Ensembl:ENSG00000136634 HGNC:5962 HPRD:00495 MIM:124092 Vega:OTTHUMG00000036386 IL10 Bin Zhao, Yue Liu, Oliver He AGIF IL-11 WEB: http://www.ncbi.nlm.nih.gov/gene IL11 interleukin 11 3589 19q13.3-q13.4 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005125 (EC: IEA); GO_0005142 (EC: NAS, PMID: 2145578); GO_0005576 (EC: IC, PMID: 2145578); GO_0005615 (EC: IEA); GO_0005737 (EC: IEA); GO_0007267 (EC: IC, PMID: 2145578); GO_0008083 (EC: IDA, PMID: 2145578); GO_0008284 (EC: IDA, PMID: 2145578); GO_0030183 (EC: NAS, PMID: 2145578); GO_0030219 (EC: NAS, PMID: 2145578); GO_0033138 (EC: IDA, PMID: 7508917); GO_0043410 (EC: IDA, PMID: 7508917); GO_0045444 (EC: NAS, PMID: 1828438); GO_0045944 (EC: IDA, PMID: 7508917); GO_0046888 (EC: IDA, PMID: 7867561); GO_0050731 (EC: IDA, PMID: 7508917) PMID: 1292471; 1386338; 1828438; 2145578; 7499280; 7508917; 7670098; 7867561; 8383296; 8913282; 8940087; 10026196; 10504396; 10725745; 10948192; 11940481; 12005542; 12032273; 12197884; 12477932; 12486609; 12569176; 12584029; 12629504; 12740032; 12760902; 12819039; 14734714; 15004839; 15025215; 15121272; 15307108; 15377473; 15381181; 15389536; 15489334; 15504551; 15543003; 15613426; 15614128; 15784719; 16149067; 16189514; 16614887; 16709613; 16759877; 16964382; 17000646; 17295091; 17325843; 17332920; 17702845; 17703412; 17713553; 18204920; 18433382; 18490653; 18941632; 18987331; 19121317; 19213836; 19223152; 19251839; 19258923; 19548631; 19647472; 19716605; 19801577; 19913506; 20008143; 20360315; 20503287; 20553623; 20640990; 20712807; 21042281; 21138838; 21155043; 21442077; 21443102; 21485496; 21688123; 21741611; 21840908; 21986128; 21995459; 22168497; 22180059; 22205539; 22253262; 22289923; 22393310; 22433466; 22457856; 22523320; 22568077; 22595646; 22614117; 22644863; 22707562; 22727646; 23027619; 23226926; 23307318; 23311882; 23317891; 23340433; 23549086; 23639700; 23813214; 24036113; 24219324; 24297922 interleukin 11 Ensembl:ENSG00000095752 HGNC:5966 HPRD:00980 MIM:147681 Vega:OTTHUMG00000180789 IL11 Bin Zhao, Yue Liu, Oliver He CLMF IL-12A NFSK NKSF1 P35 WEB: http://www.ncbi.nlm.nih.gov/gene IL12A interleukin 12A 3592 3q25.33 20140409 9606 3 protein-coding Official from a nomenclature committee GO_0001916 (EC: IDA, PMID: 1674604); GO_0002860 (EC: IDA, PMID: 7903063); GO_0005125 (EC: IDA, Qualifier: contributes_to, PMID: 1674604); GO_0005125 (EC: TAS, Qualifier: contributes_to, PMID: 1673147); GO_0005143 (EC: NAS, PMID: 1674604); GO_0005515 (EC: IPI, PMID: 10899108); GO_0005615 (EC: IDA, PMID: 16456693); GO_0005737 (EC: IEA); GO_0006955 (EC: TAS, PMID: 9789052); GO_0007050 (EC: IDA, PMID: 16942485); GO_0008083 (EC: IDA, Qualifier: contributes_to, PMID: 1674604); GO_0008083 (EC: NAS, Qualifier: contributes_to, PMID: 1673147); GO_0009615 (EC: IEP, PMID: 16548883); GO_0010224 (EC: IDA, PMID: 8992506); GO_0016477 (EC: IDA, PMID: 7903063); GO_0032496 (EC: IDA, PMID: 7605994); GO_0032700 (EC: IDA, PMID: 16482511); GO_0032729 (EC: IDA, PMID: 11114383); GO_0032816 (EC: IDA, PMID: 1674604); GO_0034393 (EC: IDA, PMID: 16942485); GO_0042102 (EC: IEA); GO_0042163 (EC: IEA); GO_0042520 (EC: IDA, PMID: 12372421); GO_0042832 (EC: IEA); GO_0043514 (EC: IDA, PMID: 11114383); GO_0043514 (EC: NAS, PMID: 14718574); GO_0045513 (EC: IPI, PMID: 9342359); GO_0045582 (EC: IEA); GO_0045785 (EC: IDA, PMID: 7903063); GO_0045954 (EC: IDA, PMID: 2204066); GO_0046982 (EC: IPI, PMID: 1674604); GO_0048662 (EC: IDA, PMID: 16942485); GO_0050671 (EC: IDA, PMID: 1674604); GO_0050830 (EC: IEP, PMID: 1357073); GO_0051135 (EC: IDA, PMID: 19088061); GO_0097191 (EC: IDA, PMID: 16942485) PMID: 934235; 1350290; 1357073; 1358798; 1673147; 1674604; 2204066; 7516408; 7527811; 7605994; 7695626; 7867080; 7903063; 8557999; 8648753; 8700208; 8760829; 8992506; 9108403; 9158092; 9225992; 9334723; 9342359; 9516412; 9603732; 9616161; 9671213; 9712080; 9789052; 10089131; 10320373; 10352291; 10899108; 11087201; 11114383; 11751963; 11940489; 12117904; 12213961; 12242445; 12270766; 12358856; 12370346; 12372421; 12444143; 12472178; 12477932; 12542496; 12558814; 12576336; 12633940; 12672403; 12719551; 12911539; 12944981; 14566095; 14597672; 14629328; 14660053; 14675394; 14718574; 14764743; 14962816; 15051764; 15087447; 15142381; 15170937; 15331709; 15356557; 15361128; 15448160; 15489234; 15643599; 15741223; 15780175; 15810889; 15817944; 15863393; 15937086; 15956545; 15963597; 16230423; 16456693; 16482511; 16544245; 16548883; 16573560; 16702372; 16754651; 16803996; 16862120; 16885196; 16938461; 16942485; 16961803; 17002904; 17007011; 17062130; 17077296; 17152005; 17225924; 17236132; 17257312; 17304101; 17361014; 17431094; 17444864; 17461482; 17509455; 17553352; 17564777; 17586317; 17627763; 17640324; 17653830; 17671745; 17703412; 17846855; 17881511; 17922692; 17947455; 18050195; 18092318; 18159163; 18190588; 18260379; 18300344; 18311140; 18385764; 18413324; 18417583; 18419254; 18554158; 18566447; 18588867; 18606709; 18628242; 18632425; 18633131; 18671862; 18672993; 18676680; 18717726; 18773331; 18805825; 18972297; 18976327; 19012493; 19013323; 19031096; 19073967; 19074885; 19088061; 19117745; 19118071; 19126646; 19144161; 19148899; 19170196; 19200845; 19230467; 19234184; 19253530; 19258923; 19275586; 19297619; 19299334; 19332120; 19339796; 19376105; 19408823; 19454678; 19458352; 19470040; 19505916; 19508433; 19516896; 19525953; 19543959; 19566870; 19573080; 19594368; 19625176; 19646340; 19692168; 19693089; 19710469; 19773279; 19789190; 19797506; 19798410; 19879194; 19885559; 19913121; 19950173; 19956842; 20012528; 20027291; 20054003; 20060272; 20061784; 20082482; 20190752; 20213229; 20231901; 20237496; 20331378; 20350312; 20372811; 20418110; 20446002; 20452482; 20453000; 20485444; 20503287; 20521253; 20544370; 20551083; 20555355; 20568250; 20581146; 20603050; 20628086; 20634089; 20639880; 20647273; 20673868; 20714168; 20716621; 20818961; 20881642; 20960273; 21044109; 21086908; 21145044; 21177981; 21285006; 21387004; 21397857; 21399635; 21402701; 21513752; 21518507; 21518761; 21606320; 21689404; 21833088; 21878338; 22005588; 22011063; 22038227; 22040814; 22133036; 22438968; 22581790; 22614250; 22655069; 22656398; 22691562; 22734699; 22819329; 22940148; 23053983; 23065210; 23154182; 23285065; 23291587; 23297419; 23377640; 23388728; 23619469; 23657466; 23717436; 23734222; 23752604; 23755218; 24273881 interleukin 12A Ensembl:ENSG00000168811 HGNC:5969 HPRD:01193 MIM:161560 Vega:OTTHUMG00000158942 IL12A Bin Zhao, Yue Liu, Oliver He LCF NIL16 PRIL16 prIL-16 WEB: http://www.ncbi.nlm.nih.gov/gene IL16 interleukin 16 3603 15q26.3 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0005125 (EC: IEA); GO_0005615 (EC: IEA); GO_0005634 (EC: IDA); GO_0005737 (EC: IDA); GO_0005886 (EC: IDA); GO_0006351 (EC: IEA); GO_0006355 (EC: IEA); GO_0006955 (EC: TAS, PMID: 9144227); GO_0016032 (EC: IEA); GO_0030595 (EC: IEA); GO_0050930 (EC: IEA) PMID: 1851800; 6729885; 7615501; 7910967; 8125298; 8599832; 8609984; 8977168; 9144227; 9271307; 9422780; 9699630; 9743378; 9990060; 10343113; 10438516; 10477592; 10479680; 11032842; 11714796; 11937573; 11999883; 12191564; 12450396; 12477932; 12620798; 12923170; 14657881; 14702039; 14705216; 14718574; 14734747; 14755377; 15175077; 15187155; 15253385; 15342983; 15383572; 15560757; 15619436; 15682385; 15784111; 15820794; 15886011; 16144798; 16177102; 16178875; 16189514; 16271292; 16344560; 16375755; 16387589; 16447204; 16455991; 17221335; 17303923; 17537415; 17551575; 17576577; 17577790; 17703412; 18006695; 18029348; 18097041; 18264096; 18394967; 18446062; 18633131; 18676870; 18768901; 18821565; 19060904; 19066394; 19073878; 19074885; 19232499; 19240061; 19258923; 19298795; 19460752; 19476022; 19758567; 19773451; 19789190; 19906316; 19913121; 20079227; 20237496; 20503287; 20529140; 20578037; 20628086; 20662556; 20800603; 20802378; 20811626; 20878214; 21036918; 21071540; 21094786; 21214401; 21267712; 21447961; 21703255; 22019522; 22080865; 22745469; 22923025; 22939228; 23020666; 23241166; 23252864; 23455924; 23881440; 23894370; 24200060 interleukin 16 Ensembl:ENSG00000172349 HGNC:5980 HPRD:04329 MIM:603035 Vega:OTTHUMG00000144186 IL16 Bin Zhao, Yue Liu, Oliver He IGIF IL-18 IL-1g IL1F4 WEB: http://www.ncbi.nlm.nih.gov/gene IL18 interleukin 18 3606 11q22.2-q22.3 20140409 9606 11 protein-coding Official from a nomenclature committee GO_0000165 (EC: IMP); GO_0001525 (EC: IDA, PMID: 11466388); GO_0005125 (EC: TAS, PMID: 11598150); GO_0005576 (EC: TAS, PMID: 11598150); GO_0005615 (EC: IEA); GO_0005829 (EC: TAS); GO_0006954 (EC: IDA); GO_0006955 (EC: TAS, PMID: 8999896); GO_0007267 (EC: TAS, PMID: 9792649); GO_0010628 (EC: IEA); GO_0030101 (EC: IEA); GO_0030155 (EC: IDA, PMID: 11477102); GO_0030431 (EC: ISS, PMID: 11506998); GO_0031663 (EC: IDA); GO_0032725 (EC: IDA); GO_0032729 (EC: IDA, PMID: 19088061); GO_0032740 (EC: IDA, PMID: 16482511); GO_0032819 (EC: IDA, PMID: 19088061); GO_0034105 (EC: IC, PMID: 16482511); GO_0042033 (EC: TAS, PMID: 11598150); GO_0042088 (EC: IDA, PMID: 8766574); GO_0042092 (EC: TAS, PMID: 11905033); GO_0042094 (EC: TAS, PMID: 10653850); GO_0042095 (EC: TAS, PMID: 10227975); GO_0042104 (EC: IDA, PMID: 10000000); GO_0042231 (EC: TAS, PMID: 10227975); GO_0042253 (EC: TAS, PMID: 10653850); GO_0042346 (EC: IEA); GO_0050729 (EC: IC, PMID: 16482511); GO_0051142 (EC: IDA, PMID: 19088061); GO_0071407 (EC: IDA) PMID: 7477296; 8666798; 8766574; 8999548; 8999896; 9108085; 9325300; 9334240; 9693051; 9792649; 10000000; 10227975; 10460493; 10639148; 10653850; 10681439; 11466388; 11477102; 11506998; 11598150; 11714750; 11714826; 11770036; 11781190; 11790772; 11798931; 11805151; 11855785; 11888846; 11894141; 11895335; 11905033; 11907126; 11920321; 11936774; 11958300; 11960649; 12096920; 12105209; 12149432; 12172382; 12207348; 12366781; 12377944; 12381835; 12387830; 12390326; 12401730; 12424620; 12438388; 12456593; 12472176; 12472673; 12477932; 12482935; 12517977; 12527894; 12571842; 12572878; 12594843; 12616343; 12654091; 12679613; 12738632; 12748489; 12759422; 12788305; 12794718; 12796418; 12819633; 12847274; 12857602; 12858406; 12874316; 12911784; 12938205; 12941729; 12947340; 14504095; 14556808; 14561165; 14581397; 14584052; 14605444; 14617033; 14630085; 14640907; 14660053; 14662834; 14679107; 14697936; 14709415; 14718574; 14725568; 14734463; 14738910; 14764217; 14960579; 14991611; 14998974; 15005726; 15104599; 15140035; 15212675; 15225625; 15230817; 15277983; 15302292; 15308504; 15326478; 15327523; 15358638; 15371332; 15463896; 15471361; 15489334; 15555533; 15581980; 15585330; 15643599; 15644127; 15645140; 15646011; 15663745; 15674367; 15710458; 15728489; 15731584; 15753257; 15760905; 15786533; 15789055; 15802534; 15806006; 15816833; 15826815; 15842270; 15860738; 15860756; 15863395; 15894108; 15896202; 15927856; 15932380; 15955098; 15963597; 16024007; 16043644; 16049975; 16051062; 16052331; 16053025; 16059673; 16061751; 16078996; 16084898; 16186395; 16215941; 16243298; 16260350; 16266857; 16273766; 16306550; 16306764; 16306765; 16315783; 16316892; 16325763; 16339124; 16358956; 16373926; 16405895; 16406079; 16406656; 16420594; 16424284; 16428475; 16433722; 16433859; 16443795; 16482511; 16492204; 16493047; 16514436; 16516851; 16556702; 16563174; 16571086; 16584830; 16621994; 16635219; 16647017; 16650813; 16671950; 16738942; 16759385; 16767839; 16772281; 16780720; 16806233; 16820919; 16827865; 16839849; 16842597; 16883062; 16903774; 16909454; 16943580; 16948912; 16971411; 16979683; 17001321; 17016692; 17027359; 17055358; 17072982; 17075246; 17077020; 17117487; 17142727; 17192354; 17222831; 17225121; 17225924; 17235324; 17237446; 17252172; 17262717; 17299019; 17301041; 17336309; 17343316; 17355643; 17361200; 17364073; 17373930; 17396252; 17399992; 17445542; 17461482; 17487222; 17517100; 17517876; 17530707; 17586702; 17597334; 17597823; 17605864; 17610422; 17611614; 17611643; 17611971; 17625598; 17626902; 17658666; 17666338; 17671745; 17674327; 17683383; 17687255; 17688413; 17691022; 17703412; 17708609; 17765248; 17767553; 17845300; 17851127; 17851835; 17854431; 17893261; 17907957; 17919265; 17922692; 17948066; 17951325; 17959666; 17962365; 17964972; 17965486; 17981284; 17984243; 17988833; 18024284; 18043444; 18050195; 18050226; 18064631; 18092318; 18093181; 18160214; 18160936; 18163476; 18165223; 18178861; 18200581; 18225542; 18225563; 18235016; 18237555; 18250135; 18279187; 18286551; 18287807; 18295214; 18295340; 18297714; 18307517; 18336908; 18359638; 18386818; 18391570; 18399311; 18433937; 18442334; 18464913; 18484687; 18504197; 18514203; 18514661; 18520705; 18523012; 18538088; 18555694; 18562922; 18566306; 18594952; 18599493; 18628791; 18632660; 18662786; 18678419; 18683145; 18684981; 18685607; 18706445; 18773860; 18777510; 18780764; 18781864; 18803662; 18818748; 18818761; 18819819; 18821674; 18835036; 18853133; 18922682; 18930181; 18937548; 18940019; 18949051; 18983635; 19016763; 19019335; 19031096; 19036565; 19064572; 19073159; 19074166; 19074885; 19077897; 19088061; 19091595; 19092166; 19097518; 19102398; 19110334; 19126646; 19131059; 19138654; 19152241; 19176284; 19178691; 19200605; 19208460; 19229765; 19230467; 19236760; 19247692; 19258923; 19263242; 19265133; 19265174; 19285156; 19288449; 19309308; 19339355; 19342689; 19347053; 19387647; 19390575; 19394601; 19403407; 19420105; 19443970; 19453784; 19455410; 19466545; 19469892; 19470251; 19473509; 19508433; 19509137; 19527514; 19538326; 19550095; 19553661; 19573080; 19581111; 19584085; 19593889; 19605669; 19622039; 19633236; 19637196; 19638090; 19638429; 19639049; 19642044; 19657406; 19669125; 19669363; 19684151; 19687159; 19692203; 19699611; 19712260; 19740312; 19745201; 19757044; 19758166; 19773279; 19789190; 19796548; 19811440; 19816189; 19817957; 19865096; 19879772; 19900154; 19907017; 19913121; 19954659; 19961286; 19961892; 20003764; 20017708; 20056178; 20060272; 20061784; 20083555; 20096599; 20097272; 20137369; 20140262; 20140691; 20150558; 20169140; 20186552; 20216908; 20227257; 20227263; 20233133; 20237496; 20304021; 20306652; 20306665; 20331838; 20331879; 20339966; 20340055; 20349123; 20350254; 20374388; 20399512; 20412718; 20414054; 20416077; 20418295; 20423837; 20424918; 20441695; 20452482; 20478055; 20482998; 20485444; 20490717; 20490891; 20522205; 20525402; 20530519; 20538124; 20545903; 20558561; 20565717; 20568250; 20586818; 20617584; 20627039; 20628086; 20673868; 20689079; 20725807; 20735470; 20797704; 20818961; 20824296; 20885390; 20960175; 20964873; 20971720; 21035858; 21061265; 21118329; 21120501; 21126942; 21139048; 21145535; 21149337; 21149398; 21224476; 21225442; 21239711; 21241672; 21249128; 21264805; 21273776; 21288140; 21321938; 21323571; 21323573; 21334074; 21336086; 21356600; 21382268; 21393015; 21394384; 21395662; 21398142; 21418456; 21418867; 21421008; 21437204; 21440322; 21448661; 21464751; 21470492; 21481392; 21484426; 21487696; 21510800; 21526496; 21532063; 21538928; 21571262; 21611751; 21636628; 21656327; 21661419; 21672342; 21681500; 21710494; 21723753; 21733366; 21742406; 21742843; 21802664; 21832842; 21836143; 21836147; 21840518; 21842238; 21864160; 21867627; 21876975; 21906983; 21922295; 21943853; 21963094; 21965503; 21969001; 21988832; 22008665; 22015107; 22058412; 22125454; 22135309; 22136483; 22141572; 22149501; 22226490; 22228436; 22289535; 22307326; 22325058; 22347372; 22364914; 22373801; 22386125; 22462419; 22468101; 22484385; 22489883; 22493490; 22515481; 22518072; 22531046; 22537138; 22537218; 22587568; 22595646; 22596175; 22613414; 22639237; 22664470; 22678894; 22686311; 22723447; 22749533; 22811364; 22825306; 22837141; 22840759; 22863216; 22883217; 22900713; 22913567; 22945280; 22980562; 22996386; 23000965; 23018032; 23023653; 23027874; 23028054; 23056251; 23073298; 23075512; 23085113; 23121308; 23132931; 23137633; 23153245; 23171362; 23178856; 23207179; 23214284; 23232703; 23238919; 23242610; 23257837; 23269628; 23276493; 23298491; 23302036; 23327592; 23403235; 23419721; 23433789; 23459183; 23499732; 23522322; 23526823; 23546966; 23557801; 23587914; 23603311; 23632060; 23656272; 23675517; 23702484; 23702978; 23707237; 23723976; 23741523; 23746337; 23793845; 23794112; 23883285; 23885403; 23888552; 23901078; 23904224; 23938462; 24331389 interleukin 18 Ensembl:ENSG00000150782 HGNC:5986 HPRD:02976 MIM:600953 Vega:OTTHUMG00000167006 IL18 Bin Zhao, Yue Liu, Oliver He IDDM1 IDDM2 ILPR IRDN MODY10 WEB: http://www.ncbi.nlm.nih.gov/gene INS insulin 3630 11p15.5 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0000165 (EC: IDA, PMID: 11278339); GO_0002020 (EC: IPI); GO_0002674 (EC: IDA, PMID: 11443198); GO_0005158 (EC: IDA, PMID: 7556975); GO_0005158 (EC: IPI, PMID: 8452530); GO_0005159 (EC: IPI, PMID: 8452530); GO_0005179 (EC: IC, PMID: 9667398); GO_0005179 (EC: IMP, PMID: 381941); GO_0005179 (EC: NAS, PMID: 14986111); GO_0005515 (EC: IPI, PMID: 9388210); GO_0005576 (EC: IC, PMID: 7556975); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 9667398); GO_0005788 (EC: TAS); GO_0005796 (EC: TAS); GO_0006006 (EC: IEA); GO_0006112 (EC: TAS); GO_0006355 (EC: NAS, PMID: 12881524); GO_0006521 (EC: IMP, PMID: 3553851); GO_0006953 (EC: IDA, PMID: 14739855); GO_0007186 (EC: IDA, PMID: 9092559); GO_0007267 (EC: IC, PMID: 7556975); GO_0008284 (EC: IDA, PMID: 17925406); GO_0008286 (EC: TAS); GO_0014068 (EC: IDA, PMID: 7688386); GO_0015758 (EC: IDA, PMID: 14615391); GO_0022898 (EC: IDA, PMID: 14615391); GO_0030307 (EC: NAS, PMID: 11742412); GO_0030335 (EC: ISS, PMID: 12138094); GO_0031018 (EC: TAS); GO_0031904 (EC: TAS); GO_0031954 (EC: ISS, PMID: 3518947); GO_0032148 (EC: IDA, PMID: 8702995); GO_0032270 (EC: IMP, PMID: 3553851); GO_0032460 (EC: IDA, PMID: 9830016); GO_0032880 (EC: IDA, PMID: 14615391); GO_0033861 (EC: IDA, PMID: 11443198); GO_0034774 (EC: TAS); GO_0042060 (EC: IDA, PMID: 9498508); GO_0042177 (EC: IDA, PMID: 15185208); GO_0042593 (EC: IMP, PMID: 381941); GO_0042802 (EC: IPI); GO_0043410 (EC: IDA, PMID: 11500939); GO_0044267 (EC: TAS); GO_0044281 (EC: TAS); GO_0045429 (EC: NAS, PMID: 14615391); GO_0045597 (EC: NAS, PMID: 11742412); GO_0045721 (EC: NAS, PMID: 11742412); GO_0045725 (EC: IDA, PMID: 17925406); GO_0045740 (EC: IDA, PMID: 7688386); GO_0045818 (EC: IMP, PMID: 381941); GO_0045821 (EC: IDA, PMID: 7688386); GO_0045821 (EC: IMP, PMID: 381941); GO_0045840 (EC: IDA, PMID: 10644978); GO_0045861 (EC: IMP, PMID: 3553851); GO_0045908 (EC: NAS, PMID: 12946932); GO_0045909 (EC: NAS, PMID: 14744991); GO_0045922 (EC: IMP, PMID: 1184755); GO_0046326 (EC: IDA, PMID: 14615391); GO_0046628 (EC: IDA, PMID: 7688386); GO_0046631 (EC: IDA, PMID: 10604997); GO_0046889 (EC: NAS, PMID: 11742412); GO_0050708 (EC: IDA, PMID: 15591776); GO_0050709 (EC: IDA, PMID: 14739855); GO_0050715 (EC: IDA, PMID: 15473891); GO_0050731 (EC: IDA, PMID: 11278339); GO_0050796 (EC: TAS); GO_0050995 (EC: NAS, PMID: 11742412); GO_0051000 (EC: NAS, PMID: 12135947); GO_0051092 (EC: IDA, PMID: 19727662); GO_0051897 (EC: IDA, PMID: 11500939); GO_0055089 (EC: IMP, PMID: 1184755); GO_0060266 (EC: IDA, PMID: 11443198); GO_0060267 (EC: IDA, PMID: 9092559); GO_0090277 (EC: TAS, PMID: 11387233); GO_0090336 (EC: TAS, PMID: 11387233); GO_1902176 (EC: NAS, PMID: 16604263); GO_2000252 (EC: IDA, PMID: 17957153) PMID: 195962; 381941; 503234; 1184755; 1406615; 1433291; 1601997; 1646635; 1851182; 1959628; 2036420; 2196279; 2271664; 2550426; 3470784; 3511099; 3518947; 3537011; 3553851; 4019786; 4443293; 4698553; 4698555; 4803504; 5101771; 5560404; 6243748; 6248962; 6253909; 6312455; 6351842; 6382002; 6424111; 6927840; 7027261; 7350438; 7477119; 7556975; 7688386; 7716547; 7773291; 7818556; 8358440; 8421693; 8452530; 8496180; 8524413; 8702995; 8971927; 9092559; 9141561; 9235985; 9388210; 9498508; 9631292; 9667398; 9773776; 9830016; 10084601; 10383393; 10497219; 10604997; 10644978; 10909971; 10938588; 10966857; 10969839; 11101842; 11140838; 11145591; 11278339; 11347740; 11376336; 11387233; 11398136; 11443198; 11500939; 11502799; 11511079; 11606170; 11738155; 11739440; 11742412; 11779231; 11779865; 11800057; 11866509; 11912547; 11937112; 11953210; 11978629; 12021212; 12029093; 12032154; 12047362; 12051853; 12072386; 12079889; 12086926; 12101177; 12111440; 12133430; 12135947; 12138094; 12182905; 12186542; 12189018; 12364457; 12378388; 12392301; 12404181; 12441313; 12477932; 12479880; 12529491; 12589110; 12610512; 12620428; 12624089; 12631734; 12637980; 12639765; 12654724; 12660731; 12709672; 12715715; 12721156; 12750767; 12803245; 12821730; 12881524; 12930990; 12946932; 12952878; 13658959; 14426955; 14551916; 14607844; 14615391; 14616883; 14633852; 14647005; 14651526; 14657411; 14659752; 14671163; 14671189; 14671204; 14679083; 14693412; 14707040; 14715866; 14739855; 14744991; 14749349; 14979729; 14986111; 15028719; 15046555; 15047631; 15070567; 15095040; 15111508; 15126243; 15161800; 15163889; 15170498; 15185208; 15194403; 15220197; 15220214; 15230641; 15237706; 15240646; 15265780; 15277396; 15305767; 15342556; 15351621; 15367890; 15473891; 15489334; 15529622; 15538935; 15561961; 15581831; 15583859; 15589123; 15591776; 15610006; 15613433; 15616007; 15632182; 15678496; 15684637; 15699505; 15705595; 15705917; 15792832; 15834700; 15880482; 15889096; 15919610; 15920061; 15922332; 15928253; 15929679; 15936461; 15949705; 15956217; 15956745; 15983206; 16006430; 16025255; 16025839; 16081366; 16123374; 16246845; 16251897; 16276008; 16307231; 16344718; 16344925; 16362283; 16380501; 16390390; 16418171; 16497805; 16519889; 16531418; 16552513; 16595598; 16604263; 16608900; 16614815; 16629714; 16691379; 16731532; 16731859; 16736556; 16741735; 16751187; 16799400; 16800793; 16835468; 16866381; 16868061; 16885156; 16949073; 16951936; 16996478; 17011062; 17011566; 17051221; 17052889; 17053071; 17065334; 17068290; 17103462; 17105729; 17116217; 17127405; 17130532; 17157312; 17192475; 17192483; 17242212; 17279313; 17284223; 17291451; 17299081; 17310371; 17311896; 17327422; 17327454; 17337306; 17341563; 17342078; 17344504; 17348446; 17416760; 17433504; 17437081; 17461431; 17464100; 17468256; 17471492; 17473382; 17479246; 17487982; 17497031; 17506723; 17513702; 17520407; 17553505; 17554260; 17586504; 17616349; 17620332; 17632545; 17652220; 17667841; 17675047; 17698984; 17700581; 17726611; 17805200; 17828388; 17846745; 17855560; 17890489; 17898179; 17901401; 17914103; 17920639; 17923791; 17925406; 17937736; 17957153; 17972051; 17993259; 18029081; 18029348; 18039179; 18039812; 18040865; 18057381; 18070774; 18072146; 18077505; 18083784; 18085551; 18090240; 18093308; 18157793; 18162506; 18171712; 18192540; 18198306; 18198311; 18211635; 18216377; 18220656; 18279373; 18283245; 18283256; 18283260; 18284601; 18292987; 18294642; 18305020; 18307789; 18310307; 18375961; 18388898; 18404969; 18417529; 18441389; 18451997; 18483566; 18520331; 18582564; 18620562; 18660489; 18662362; 18692115; 18716398; 18719673; 18834984; 18839133; 18840770; 18853485; 18940880; 18951876; 18981553; 18983503; 18996102; 19000139; 19000992; 19020323; 19025443; 19037607; 19051206; 19052261; 19064572; 19073905; 19073967; 19094425; 19115062; 19141582; 19146426; 19152242; 19188433; 19188609; 19190820; 19214176; 19247282; 19249902; 19321435; 19321436; 19321446; 19324891; 19336408; 19338578; 19367319; 19430480; 19434426; 19445897; 19463742; 19466592; 19491387; 19556358; 19578600; 19578796; 19602055; 19680231; 19683528; 19688775; 19709092; 19727662; 19742322; 19767753; 19769745; 19778377; 19785038; 19833889; 19845278; 19885595; 19898946; 19913026; 19913121; 19935854; 19948072; 19950226; 20007936; 20033399; 20034470; 20054344; 20098959; 20106974; 20119675; 20133622; 20133841; 20138117; 20142200; 20190549; 20203524; 20208155; 20226046; 20232313; 20301620; 20332111; 20345871; 20357092; 20357430; 20361993; 20378605; 20391195; 20455999; 20468064; 20535137; 20564319; 20566319; 20587420; 20607677; 20628086; 20628762; 20647273; 20655470; 20679359; 20724178; 20734064; 20738396; 20739464; 20805278; 20808760; 20849903; 20863361; 20938745; 21036154; 21054880; 21059249; 21073664; 21094141; 21193298; 21193618; 21203453; 21203503; 21251282; 21281583; 21302286; 21308844; 21336277; 21352425; 21361910; 21412422; 21427225; 21437235; 21442164; 21448434; 21454690; 21454697; 21462967; 21473587; 21507316; 21544516; 21559376; 21566073; 21574953; 21592955; 21646299; 21660954; 21707690; 21711374; 21724851; 21813805; 21816162; 21823539; 21829393; 21832049; 21867683; 21871813; 21887289; 21900206; 21906630; 21911493; 22003494; 22005517; 22033917; 22065208; 22065581; 22068552; 22082268; 22095122; 22132167; 22132232; 22167125; 22167126; 22193626; 22229322; 22235272; 22242132; 22253890; 22290178; 22297303; 22307032; 22315413; 22319034; 22357962; 22359667; 22378730; 22379117; 22383948; 22393448; 22403629; 22465905; 22468791; 22547909; 22567146; 22577092; 22718751; 22739332; 22748134; 22751690; 22763970; 22883454; 22918957; 22940118; 22949029; 22950808; 22957706; 22967498; 22967500; 22972030; 22982989; 23018458; 23043361; 23050777; 23092880; 23133528; 23223446; 23227203; 23275337; 23289766; 23302862; 23321478; 23347689; 23348915; 23357976; 23405181; 23410103; 23428413; 23443243; 23447530; 23460020; 23463541; 23484124; 23510797; 23531221; 23584706; 23600561; 23624892; 23648896; 23697264; 23718986; 23796517; 23820621; 23886629; 23911422; 23933688; 23936387; 23980258; 24022479; 24036112; 24184209; 24283070; 24479346 insulin Ensembl:ENSG00000254647 HGNC:6081 HPRD:01455 MIM:176730 Vega:OTTHUMG00000009558 INS Bin Zhao, Yue Liu, Oliver He SHIP SHIP-1 SHIP1 SIP-145 hp51CN p150Ship WEB: http://www.ncbi.nlm.nih.gov/gene INPP5D inositol polyphosphate-5-phosphatase, 145kDa 3635 2q37.1 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0004445 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10382761); GO_0005829 (EC: TAS); GO_0006644 (EC: TAS); GO_0006661 (EC: TAS); GO_0006796 (EC: TAS, PMID: 8769125); GO_0006915 (EC: IEA); GO_0007165 (EC: TAS, PMID: 8769125); GO_0007596 (EC: TAS); GO_0008340 (EC: IEA); GO_0009968 (EC: IEA); GO_0016020 (EC: IEA); GO_0016064 (EC: IEA); GO_0017124 (EC: IEA); GO_0030889 (EC: IEA); GO_0034594 (EC: IEA); GO_0035556 (EC: IEA); GO_0043065 (EC: IEA); GO_0043647 (EC: TAS); GO_0044281 (EC: TAS); GO_0045409 (EC: IEA); GO_0045579 (EC: IEA); GO_0045648 (EC: IEA); GO_0045656 (EC: IEA); GO_0045659 (EC: IEA); GO_0045671 (EC: IEA); GO_0045779 (EC: IEA); GO_0046856 (EC: IEA); GO_0050777 (EC: IEA); GO_0050852 (EC: TAS); GO_0050900 (EC: TAS); GO_0051425 (EC: IEA) PMID: 8643691; 8654924; 8723348; 8769125; 8874179; 9058707; 9108392; 9110989; 9148918; 9341117; 9422771; 9531585; 9918857; 10194451; 10229804; 10350061; 10382761; 10660611; 10704825; 10733577; 10748054; 10822173; 10875931; 10900203; 11071635; 11157475; 11247302; 11287610; 11402314; 11443118; 11692111; 11714803; 11724799; 12024011; 12029088; 12217402; 12393695; 12421919; 12477932; 12829595; 12882960; 14688341; 14702039; 14993273; 15090612; 15166241; 15184070; 15470047; 15492005; 15604218; 15644415; 15735664; 15944314; 15953601; 16038794; 16406061; 16428799; 16619039; 16682172; 16818760; 17342744; 17371259; 17657219; 19041431; 19380743; 19473701; 19641183; 19682241; 19839650; 19880507; 19890474; 19913121; 19954644; 20041145; 20304029; 20331378; 20379614; 20628086; 20697350; 20972266; 21155837; 21275903; 21378990; 21402888; 21622861; 21695085; 21864674; 21906983; 22249254; 22267732; 22412388; 22575191; 22706086; 22815893; 22820502; 23128233; 23154388; 23998585; 24095650; 24302498; 24391219; 24522920 inositol polyphosphate-5-phosphatase, 145kDa Ensembl:ENSG00000168918 HGNC:6079 HPRD:09033 MIM:601582 INPP5D Bin Zhao, Yue Liu, Oliver He CD220 HHF5 WEB: http://www.ncbi.nlm.nih.gov/gene INSR insulin receptor 3643 19p13.3-p13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000187 (EC: IMP, PMID: 17001305); GO_0001934 (EC: IDA, PMID: 7556070); GO_0003007 (EC: IMP, PMID: 7693131); GO_0004713 (EC: IDA, PMID: 8496180); GO_0004713 (EC: IMP, PMID: 7537849); GO_0004716 (EC: IDA, PMID: 6849137); GO_0005009 (EC: IDA, PMID: 6849137); GO_0005159 (EC: IDA, PMID: 8452530); GO_0005515 (EC: IPI, PMID: 10500481); GO_0005524 (EC: IDA, PMID: 6849137); GO_0005525 (EC: IDA, PMID: 9092559); GO_0005886 (EC: IC, PMID: 6849137); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 9092559); GO_0005899 (EC: IMP, PMID: 15069075); GO_0005901 (EC: IDA, PMID: 15182363); GO_0005975 (EC: IEA); GO_0006355 (EC: IMP, PMID: 12881524); GO_0007186 (EC: IDA, PMID: 9092559); GO_0008284 (EC: IC, PMID: 11500939); GO_0008284 (EC: IDA, PMID: 17925406); GO_0008286 (EC: IDA, PMID: 6849137); GO_0008286 (EC: TAS); GO_0010008 (EC: TAS); GO_0016020 (EC: IDA, PMID: 8452530); GO_0018108 (EC: IDA, PMID: 8496180); GO_0019087 (EC: IMP, PMID: 17001305); GO_0023014 (EC: IDA, PMID: 6849137); GO_0030238 (EC: IEA); GO_0030335 (EC: IMP, PMID: 12138094); GO_0031017 (EC: IEA); GO_0031994 (EC: IPI, PMID: 8452530); GO_0031995 (EC: IPI, PMID: 12138094); GO_0032147 (EC: IMP, PMID: 9819385); GO_0032148 (EC: IDA, PMID: 7556070); GO_0032869 (EC: IDA, PMID: 8440175); GO_0042169 (EC: IPI, PMID: 8276809); GO_0042593 (EC: IMP, PMID: 7693131); GO_0043235 (EC: IDA); GO_0043410 (EC: IMP, PMID: 11500939); GO_0043548 (EC: IPI, PMID: 7537849); GO_0043559 (EC: IDA, PMID: 8440175); GO_0043559 (EC: IPI, PMID: 8452530); GO_0043560 (EC: IPI, PMID: 7493946); GO_0045429 (EC: IMP, PMID: 10747347); GO_0045725 (EC: IDA, PMID: 17925406); GO_0045740 (EC: IMP, PMID: 12138094); GO_0045821 (EC: IMP, PMID: 7693131); GO_0045840 (EC: IMP, PMID: 11500939); GO_0045995 (EC: IMP, PMID: 7693131); GO_0046326 (EC: IDA, PMID: 3518947); GO_0046326 (EC: NAS, PMID: 11001060); GO_0046777 (EC: IDA, PMID: 6849137); GO_0046777 (EC: IMP, PMID: 7537849); GO_0048639 (EC: IMP, PMID: 7693131); GO_0051290 (EC: IDA, PMID: 1898103); GO_0051425 (EC: IPI, PMID: 7559478); GO_0051897 (EC: IMP, PMID: 11500939); GO_0060267 (EC: IDA, PMID: 9092559); GO_0070062 (EC: IDA); GO_0071363 (EC: IEA) PMID: 185872; 1304913; 1314826; 1315125; 1321126; 1321605; 1324934; 1331107; 1373652; 1472036; 1563582; 1607067; 1607076; 1644241; 1648089; 1657953; 1730625; 1890161; 1898103; 1956339; 1963473; 1971035; 1986371; 1993068; 2002058; 2040394; 2121734; 2168397; 2210055; 2211730; 2280779; 2365819; 2369896; 2460770; 2479553; 2538124; 2544997; 2544998; 2550426; 2566545; 2573522; 2777789; 2806055; 2834824; 2842060; 2859121; 2983222; 2986535; 3101064; 3109943; 3166375; 3283938; 3447155; 3518947; 3546306; 3680248; 6849137; 7028018; 7479769; 7493946; 7512963; 7529876; 7535775; 7537849; 7538143; 7556070; 7559478; 7592607; 7613486; 7626603; 7657032; 7693131; 7794689; 7806540; 7815442; 7836419; 7860063; 7895674; 7906861; 7926007; 7929343; 7935368; 7953556; 7983039; 7997262; 8027066; 8082780; 8096518; 8101305; 8114715; 8135823; 8188715; 8242067; 8243830; 8276809; 8288049; 8314008; 8326490; 8347587; 8385099; 8388389; 8390949; 8419945; 8432414; 8440175; 8452530; 8454633; 8458533; 8463287; 8463311; 8496180; 8504096; 8513978; 8557631; 8603569; 8621530; 8626379; 8636294; 8639568; 8662806; 8692915; 8702728; 8826975; 8890729; 8900242; 8912646; 8916919; 9006901; 9083103; 9092546; 9092559; 9121430; 9122188; 9175790; 9195949; 9197239; 9199575; 9249867; 9299395; 9312016; 9355745; 9398630; 9428692; 9446569; 9449692; 9492017; 9506989; 9507031; 9524259; 9658397; 9703342; 9710204; 9722981; 9741627; 9742218; 9748281; 9756945; 9819385; 9819414; 10026153; 10084586; 10196204; 10340378; 10437794; 10443650; 10453981; 10482988; 10500481; 10594240; 10598578; 10615944; 10635327; 10650943; 10733238; 10747347; 10764799; 10803466; 10805733; 10816433; 10830280; 10871840; 10896916; 10921922; 10978177; 11001060; 11071852; 11075717; 11094073; 11158333; 11208515; 11232039; 11260230; 11266508; 11279102; 11289049; 11342531; 11374898; 11401470; 11409918; 11500939; 11506178; 11551902; 11604231; 11606564; 11694516; 11726652; 11735220; 11781100; 11866509; 11875066; 11994298; 11997497; 12023989; 12031977; 12031982; 12107746; 12112020; 12125099; 12138094; 12153558; 12193537; 12237455; 12237775; 12270939; 12420346; 12456798; 12468540; 12477518; 12477932; 12493740; 12504111; 12538626; 12560330; 12575209; 12612081; 12613967; 12634852; 12654724; 12660731; 12665574; 12711007; 12730241; 12732844; 12734206; 12738810; 12850828; 12878213; 12881524; 12970295; 14551916; 14568990; 14690593; 14693412; 14722023; 14729945; 15031295; 15061947; 15069075; 15114529; 15161766; 15169905; 15182363; 15192089; 15205474; 15233842; 15240646; 15337529; 15485753; 15498182; 15514089; 15522217; 15563471; 15581831; 15582274; 15588985; 15590636; 15629149; 15632081; 15664450; 15694368; 15708546; 15715521; 15735664; 15738637; 15745246; 15767667; 15799978; 15862945; 15924147; 15938783; 15951569; 16084832; 16127460; 16137651; 16314505; 16382134; 16434550; 16473310; 16510536; 16582879; 16761106; 16806206; 16814253; 16831875; 16946708; 16962112; 17001305; 17078079; 17102568; 17159996; 17201797; 17221153; 17229154; 17275003; 17325037; 17340225; 17344070; 17348446; 17374711; 17416760; 17434141; 17445799; 17475934; 17556377; 17563065; 17563366; 17577576; 17620296; 17658524; 17854350; 17855343; 17914103; 17925406; 17957771; 17965293; 18048361; 18249389; 18318661; 18348886; 18455362; 18535540; 18556968; 18616667; 18660489; 18676680; 18693051; 18708119; 18711691; 18716398; 18767165; 18785179; 18828733; 18834871; 18925540; 18991400; 18996102; 19047369; 19051206; 19064572; 19135752; 19139090; 19167335; 19170196; 19170714; 19211708; 19219452; 19246519; 19326042; 19387820; 19406747; 19459609; 19541767; 19560451; 19575708; 19578796; 19625176; 19654240; 19688022; 19692168; 19720790; 19815552; 19817984; 19835884; 19898946; 19913121; 19926323; 19948975; 19950604; 19996272; 20009360; 20068229; 20200332; 20339196; 20348418; 20360006; 20360068; 20416077; 20421297; 20468064; 20493471; 20521171; 20568733; 20602615; 20620597; 20624623; 20628086; 20634197; 20674666; 20734064; 20849815; 20855565; 20857837; 20881960; 20971123; 21082232; 21113646; 21123448; 21139137; 21177763; 21204696; 21300347; 21318406; 21346174; 21410323; 21441570; 21487008; 21524684; 21535266; 21602145; 21645371; 21680660; 21838706; 21869538; 21906983; 21908557; 21913804; 21963094; 21987572; 21988832; 22017372; 22046260; 22081023; 22082268; 22099628; 22132154; 22140443; 22140505; 22161861; 22189999; 22278432; 22278734; 22318726; 22404968; 22438913; 22466604; 22493691; 22505724; 22534794; 22541124; 22590634; 22629383; 22705438; 22768670; 22775283; 22825921; 22879999; 22885925; 22971162; 22974441; 22982059; 23018458; 23059533; 23190452; 23251408; 23263486; 23302862; 23303383; 23348915; 23363253; 23386514; 23395167; 23408906; 23602568; 23633480; 23666741; 23697264; 24078630 insulin receptor Ensembl:ENSG00000171105 HGNC:6091 HPRD:00975 MIM:147670 Vega:OTTHUMG00000181992 INSR Bin Zhao, Yue Liu, Oliver He ACO3 IRP2 IRP2AD WEB: http://www.ncbi.nlm.nih.gov/gene IREB2 iron-responsive element binding protein 2 3658 15q25.1 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0003723 (EC: IDA, PMID: 7983023); GO_0003723 (EC: TAS, PMID: 9924025); GO_0005515 (EC: IPI, PMID: 19762596); GO_0005737 (EC: NAS, PMID: 7983023); GO_0005739 (EC: IEA); GO_0005829 (EC: IEA); GO_0006417 (EC: IEA); GO_0006782 (EC: IEA); GO_0006826 (EC: TAS, PMID: 9924025); GO_0006879 (EC: IEA); GO_0007568 (EC: IEA); GO_0009791 (EC: IEA); GO_0010040 (EC: IEA); GO_0030316 (EC: IEA); GO_0030350 (EC: TAS, PMID: 9924025); GO_0032526 (EC: IEA); GO_0034101 (EC: IEA); GO_0046872 (EC: IEA); GO_0050892 (EC: IEA); GO_0051539 (EC: IEA); GO_0071456 (EC: IEA) PMID: 1421965; 2172968; 7489724; 7523370; 7622457; 7983023; 9560204; 9924025; 11783942; 12192037; 12200453; 12465072; 12477932; 12629548; 12855587; 12888568; 14673166; 15057521; 15146197; 15777842; 15938636; 16503547; 16914832; 17200797; 17604281; 17613866; 17760563; 17822790; 18574241; 18582596; 19223469; 19762596; 19762597; 19800047; 20173748; 20405006; 20587604; 20587610; 20656943; 20877624; 21139048; 21320324; 21558272; 21832049; 21890473; 21906983; 21963094; 21987572; 21988832; 22079093; 22080838; 22093897; 22331484; 22356581; 22461431; 22505724; 22863883; 22914670; 23000965; 23251661; 23741361; 24285726 iron-responsive element binding protein 2 Ensembl:ENSG00000136381 HGNC:6115 HPRD:08858 MIM:147582 Vega:OTTHUMG00000143861 IREB2 Bin Zhao, Yue Liu, Oliver He HIRS-1 WEB: http://www.ncbi.nlm.nih.gov/gene IRS1 insulin receptor substrate 1 3667 2q36 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0002053 (EC: IEA); GO_0004871 (EC: IEA); GO_0005068 (EC: ISS); GO_0005080 (EC: ISS); GO_0005158 (EC: IPI, PMID: 7493946); GO_0005159 (EC: IPI, PMID: 7541045); GO_0005515 (EC: IPI, PMID: 11018022); GO_0005634 (EC: ISS); GO_0005737 (EC: ISS); GO_0005829 (EC: TAS); GO_0005886 (EC: TAS); GO_0005899 (EC: ISS); GO_0005901 (EC: IDA, PMID: 15182363); GO_0007165 (EC: TAS, PMID: 1311924); GO_0007173 (EC: TAS); GO_0008284 (EC: NAS, PMID: 17925406); GO_0008286 (EC: IDA, PMID: 16516141); GO_0008286 (EC: IMP, PMID: 16814735); GO_0008286 (EC: IPI, PMID: 7537849); GO_0008286 (EC: TAS); GO_0008543 (EC: TAS); GO_0010468 (EC: IEA); GO_0010907 (EC: IMP, PMID: 16814735); GO_0014065 (EC: IDA, PMID: 7782332); GO_0016042 (EC: IEA); GO_0030335 (EC: IEA); GO_0030879 (EC: IEA); GO_0032000 (EC: IMP, PMID: 16814735); GO_0032868 (EC: IDA, PMID: 16516141); GO_0032869 (EC: IMP, PMID: 16814735); GO_0034504 (EC: IEA); GO_0038095 (EC: TAS); GO_0042169 (EC: ISS); GO_0042593 (EC: TAS, PMID: 16814735); GO_0043231 (EC: ISS); GO_0043434 (EC: ISS); GO_0043491 (EC: IEA); GO_0043548 (EC: IPI, PMID: 16043515); GO_0043548 (EC: ISS); GO_0043552 (EC: ISS); GO_0045087 (EC: TAS); GO_0045725 (EC: IMP, PMID: 16814735); GO_0045725 (EC: NAS, PMID: 17925406); GO_0046326 (EC: IMP, PMID: 16814735); GO_0046627 (EC: ISS); GO_0046628 (EC: ISS); GO_0046676 (EC: IDA, PMID: 15572028); GO_0048009 (EC: IPI, PMID: 7541045); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0060397 (EC: TAS); GO_2001275 (EC: IDA, PMID: 7493946) PMID: 1311924; 1381348; 1648180; 7488107; 7493946; 7499194; 7499365; 7537849; 7541045; 7542745; 7559478; 7559507; 7782332; 7935368; 7935386; 8020946; 8104271; 8175658; 8240352; 8349691; 8388384; 8491186; 8505282; 8513971; 8524391; 8530377; 8536716; 8550573; 8557683; 8599766; 8621530; 8621590; 8626379; 8626671; 8631859; 8633037; 8662806; 8723689; 8732688; 8776723; 8810325; 9111084; 9174053; 9202037; 9295312; 9312143; 9415396; 9422753; 9492017; 9748281; 9756938; 9792713; 9822703; 9837978; 9843575; 10026153; 10082579; 10206679; 10411883; 10417350; 10455176; 10497255; 10660596; 10669726; 10679027; 10722755; 10843189; 10854852; 10856136; 11006284; 11018022; 11035789; 11063744; 11120660; 11147812; 11162588; 11172806; 11208867; 11287026; 11287630; 11289056; 11317670; 11522686; 11579209; 11604231; 11606564; 11694888; 11739394; 11775217; 11781100; 11872698; 11874945; 11877394; 11912194; 11969417; 11978177; 12006586; 12031982; 12107745; 12107746; 12167717; 12173038; 12213887; 12220227; 12228220; 12351658; 12354757; 12358865; 12370850; 12409308; 12414625; 12417588; 12475767; 12477526; 12477932; 12493740; 12510059; 12524443; 12554758; 12560071; 12565902; 12588284; 12606535; 12624099; 12660731; 12679424; 12730242; 12732844; 12763374; 12765939; 12783867; 12819898; 12821935; 12843189; 12910680; 12933652; 12934392; 12960006; 14511371; 14559999; 14583092; 14602724; 14604996; 14633864; 14642408; 14668342; 14671192; 14693412; 14707024; 14966273; 14968112; 14988278; 15001544; 15003536; 15044323; 15069075; 15127203; 15155816; 15161794; 15182363; 15209769; 15222685; 15240653; 15247132; 15308584; 15316008; 15318176; 15324660; 15364919; 15474880; 15489334; 15514089; 15516986; 15522123; 15561965; 15561966; 15572028; 15581831; 15582274; 15588985; 15590636; 15592455; 15604215; 15629149; 15634339; 15636429; 15665022; 15678496; 15705377; 15759454; 15778465; 15781195; 15802620; 15849359; 15926113; 15940190; 15965906; 15985484; 16020478; 16030120; 16037106; 16043515; 16084882; 16127460; 16128672; 16129678; 16129690; 16131083; 16230374; 16233930; 16273093; 16284438; 16284649; 16354680; 16367885; 16418171; 16448675; 16489531; 16516141; 16522427; 16582879; 16603055; 16648810; 16734387; 16752222; 16814735; 16914728; 16970908; 17020651; 17030605; 17030631; 17044098; 17046546; 17051426; 17068339; 17075427; 17081983; 17124363; 17179152; 17222321; 17222824; 17276034; 17279354; 17332342; 17360977; 17361103; 17374994; 17416760; 17443311; 17446166; 17459875; 17465001; 17570749; 17575262; 17591841; 17638892; 17640984; 17647275; 17719609; 17721511; 17721885; 17827156; 17827393; 17868644; 17898946; 17905199; 17908691; 17914103; 17925406; 18059035; 18208559; 18216326; 18222120; 18264722; 18285345; 18305032; 18316360; 18398029; 18498745; 18521741; 18611262; 18615395; 18615538; 18642444; 18660489; 18676680; 18710329; 18716398; 18729074; 18834857; 18851963; 18952604; 18992148; 18992263; 18996102; 19035139; 19038974; 19053277; 19117011; 19124510; 19140314; 19170196; 19259821; 19261680; 19328476; 19375584; 19391107; 19418728; 19420105; 19447894; 19453261; 19557384; 19561084; 19578796; 19625176; 19639489; 19671924; 19692168; 19716569; 19730683; 19734900; 19803812; 19843326; 19843521; 19913121; 19924529; 19926323; 19953087; 19956100; 20012307; 20170352; 20176643; 20207740; 20210696; 20229450; 20351777; 20363874; 20384434; 20416077; 20416304; 20437058; 20437825; 20452482; 20453000; 20490451; 20538960; 20540360; 20540670; 20571754; 20581827; 20602615; 20628086; 20634197; 20663861; 20673868; 20682687; 20685959; 20686565; 20730618; 20738937; 20824664; 20855565; 20977583; 21139048; 21204696; 21289241; 21325637; 21353221; 21454638; 21464990; 21465511; 21569802; 21612394; 21645940; 21666240; 21677657; 21700086; 21706003; 21706016; 21832049; 21850561; 21852217; 21917432; 21939528; 22187946; 22205343; 22266116; 22323484; 22348058; 22457523; 22479202; 22523112; 22558377; 22575725; 22576021; 22581228; 22589738; 22617042; 22664743; 22729394; 22759779; 22766331; 22824790; 22935141; 22974441; 22994406; 23000965; 23045529; 23048032; 23073384; 23147115; 23201159; 23221578; 23251408; 23353623; 23396401; 23400783; 23418314; 23460019; 23478262; 23583389; 23604317; 23606743; 23615405; 23659870; 23697264; 23708959; 23720771; 23754948; 23770097; 23818951; 23940030; 23965929; 24250222; 24550499; 24616100 insulin receptor substrate 1 Ensembl:ENSG00000169047 HGNC:6125 HPRD:00943 MIM:147545 Vega:OTTHUMG00000133179 IRS1 Bin Zhao, Yue Liu, Oliver He JTK10 THCYT3 WEB: http://www.ncbi.nlm.nih.gov/gene JAK2 Janus kinase 2 3717 9p24 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000186 (EC: IEA); GO_0004672 (EC: NAS, PMID: 9670957); GO_0004713 (EC: EXP); GO_0004713 (EC: ISS); GO_0004713 (EC: TAS); GO_0004715 (EC: IEA); GO_0005102 (EC: IPI, PMID: 11201744); GO_0005131 (EC: ISS); GO_0005143 (EC: ISS); GO_0005515 (EC: IPI, PMID: 11679576); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA, PMID: 10502458); GO_0005737 (EC: IDA, PMID: 10502458); GO_0005829 (EC: TAS); GO_0005856 (EC: IEA); GO_0005901 (EC: ISS); GO_0006468 (EC: TAS, PMID: 9670957); GO_0006915 (EC: ISS); GO_0006919 (EC: ISS); GO_0006928 (EC: TAS, PMID: 9670957); GO_0007165 (EC: ISS); GO_0007167 (EC: ISS); GO_0007186 (EC: IEA); GO_0007204 (EC: IEA); GO_0007259 (EC: TAS, PMID: 9670957); GO_0007260 (EC: ISS); GO_0007262 (EC: ISS); GO_0007498 (EC: TAS, PMID: 9590174); GO_0007596 (EC: TAS); GO_0008022 (EC: IEA); GO_0008284 (EC: IEA); GO_0008285 (EC: ISS); GO_0008631 (EC: IEA); GO_0009755 (EC: IEA); GO_0010811 (EC: IDA, PMID: 10925297); GO_0014068 (EC: ISS); GO_0016363 (EC: IEA); GO_0018108 (EC: ISS); GO_0019221 (EC: IDA, PMID: 8609418); GO_0019221 (EC: ISS); GO_0019221 (EC: TAS); GO_0019901 (EC: IDA, PMID: 10925297); GO_0020037 (EC: IDA); GO_0022408 (EC: IEA); GO_0030041 (EC: NAS, PMID: 10925297); GO_0030154 (EC: ISS); GO_0030218 (EC: ISS); GO_0030335 (EC: IEA); GO_0031103 (EC: IEA); GO_0031702 (EC: IEA); GO_0031904 (EC: TAS); GO_0031959 (EC: IEA); GO_0032024 (EC: IEA); GO_0032496 (EC: ISS); GO_0032516 (EC: IEA); GO_0032731 (EC: IEA); GO_0032760 (EC: ISS); GO_0033130 (EC: IEA); GO_0033160 (EC: IEA); GO_0033194 (EC: IEA); GO_0033209 (EC: IDA, PMID: 8609418); GO_0034050 (EC: IEA); GO_0034612 (EC: IDA, PMID: 8609418); GO_0035401 (EC: IDA, PMID: 19783980); GO_0035409 (EC: IDA, PMID: 19783980); GO_0035556 (EC: ISS); GO_0035722 (EC: IDA, PMID: 7528775); GO_0042169 (EC: IPI, PMID: 9727029); GO_0042393 (EC: IDA, PMID: 19783980); GO_0042503 (EC: IEA); GO_0042506 (EC: IEA); GO_0042508 (EC: IEA); GO_0042517 (EC: ISS); GO_0042523 (EC: ISS); GO_0042977 (EC: ISS); GO_0043065 (EC: IEA); GO_0043388 (EC: IEA); GO_0043392 (EC: ISS); GO_0043524 (EC: IEA); GO_0043548 (EC: IEA); GO_0043560 (EC: IEA); GO_0045121 (EC: ISS); GO_0045429 (EC: IEA); GO_0045597 (EC: IEA); GO_0045822 (EC: IEA); GO_0046677 (EC: IDA, PMID: 16280321); GO_0046777 (EC: ISS); GO_0048008 (EC: IEA); GO_0050727 (EC: IDA, PMID: 10925297); GO_0050729 (EC: IEA); GO_0050731 (EC: ISS); GO_0050867 (EC: IEA); GO_0051091 (EC: IEA); GO_0051428 (EC: IEA); GO_0051770 (EC: ISS); GO_0060333 (EC: TAS); GO_0060334 (EC: TAS); GO_0060396 (EC: IDA, PMID: 10925297); GO_0060397 (EC: ISS); GO_0060397 (EC: TAS); GO_0060399 (EC: ISS); GO_0061180 (EC: ISS); GO_0070671 (EC: IDA, PMID: 7528775); GO_0097191 (EC: ISS); GO_0097296 (EC: ISS); GO_2001235 (EC: IEA) PMID: 1581631; 1848670; 7499845; 7500025; 7514165; 7527392; 7528775; 7530656; 7534285; 7535773; 7540178; 7543024; 7559603; 7657660; 7673114; 7690989; 7746328; 7775438; 7812050; 7889566; 7925280; 8041779; 8063815; 8343951; 8493579; 8536716; 8608603; 8609418; 8611693; 8617237; 8626374; 8631301; 8631962; 8639815; 8657151; 8702385; 8756581; 8876196; 8912646; 8943354; 8950973; 8995399; 9012831; 9038232; 9047382; 9111318; 9126968; 9133424; 9162069; 9169451; 9178903; 9202126; 9202403; 9211920; 9326218; 9343427; 9344848; 9355737; 9363897; 9388212; 9446644; 9452495; 9473212; 9484840; 9492017; 9510175; 9516124; 9553131; 9553136; 9573010; 9575217; 9590174; 9618263; 9632636; 9670957; 9689060; 9727029; 9837922; 10026141; 10064597; 10198225; 10205168; 10224114; 10358079; 10374881; 10421843; 10455112; 10455176; 10477722; 10502458; 10506573; 10531356; 10551884; 10586060; 10635327; 10692450; 10747872; 10757801; 10772872; 10809230; 10842184; 10842319; 10872802; 10872831; 10882725; 10899310; 10918061; 10918587; 10925297; 10938266; 10954736; 10979953; 11087817; 11152457; 11163768; 11201744; 11208867; 11278610; 11278738; 11294897; 11313464; 11314018; 11350938; 11373296; 11413148; 11430697; 11438544; 11440634; 11493922; 11585385; 11591716; 11593427; 11679576; 11694501; 11698276; 11713228; 11731619; 11779507; 11818507; 11839738; 11875116; 11923474; 11934902; 11940567; 11940572; 11971965; 12007403; 12023369; 12023981; 12106016; 12207328; 12223098; 12244095; 12351625; 12370296; 12370803; 12441334; 12456798; 12456871; 12477932; 12478664; 12538627; 12540842; 12551917; 12552091; 12576423; 12626508; 12637327; 12668872; 12777975; 12817007; 12960006; 14500680; 14522994; 14551204; 14551213; 14565954; 14968112; 14978237; 14982882; 15121872; 15143187; 15143188; 15156153; 15164053; 15198092; 15284024; 15322115; 15358195; 15475610; 15514089; 15604419; 15611059; 15615703; 15666812; 15676212; 15677497; 15688010; 15767667; 15781101; 15793561; 15805263; 15821101; 15837627; 15858187; 15860661; 15863514; 15923602; 15927298; 15985214; 15985544; 15988755; 16034466; 16079889; 16084028; 16084495; 16091753; 16135792; 16174768; 16197451; 16204151; 16247455; 16257269; 16257270; 16273093; 16280321; 16293597; 16304380; 16365288; 16369984; 16373657; 16420986; 16424865; 16434490; 16434499; 16442619; 16497804; 16502590; 16503548; 16537803; 16557239; 16563504; 16572198; 16572200; 16598306; 16598312; 16603627; 16609991; 16617322; 16620973; 16627272; 16632470; 16728702; 16741247; 16757685; 16762626; 16769584; 16772604; 16804112; 16828865; 16831057; 16847321; 16849644; 16868251; 16871275; 16873677; 16877349; 16885051; 16886215; 16888614; 16904848; 16912864; 16923108; 16926301; 16929538; 16930139; 16932338; 16954506; 16959222; 16959246; 16982687; 16987804; 16990759; 16990780; 17012261; 17027227; 17045648; 17052978; 17054914; 17057021; 17068151; 17077140; 17105449; 17110452; 17111143; 17151700; 17169814; 17190855; 17198871; 17229651; 17229652; 17237409; 17249502; 17262192; 17263783; 17266061; 17267906; 17296581; 17296594; 17307838; 17315023; 17344140; 17344916; 17356406; 17363731; 17376889; 17379742; 17389152; 17389763; 17392820; 17403204; 17408106; 17426257; 17439832; 17440677; 17440984; 17443220; 17452518; 17460706; 17474147; 17476275; 17476276; 17488346; 17507997; 17507998; 17509995; 17540852; 17546465; 17565041; 17573918; 17577920; 17581610; 17596137; 17597810; 17611555; 17611562; 17613428; 17625156; 17625603; 17625606; 17625610; 17625612; 17639043; 17643100; 17652621; 17689208; 17703302; 17703412; 17706283; 17707884; 17712047; 17726017; 17727557; 17761748; 17761766; 17764814; 17764815; 17849060; 17851549; 17851561; 17851851; 17854308; 17873518; 17875526; 17881638; 17914411; 17919086; 17920754; 17920755; 17949475; 17961178; 17972958; 17976519; 17982107; 17983808; 17984312; 17989398; 18000612; 18003935; 18006699; 18032883; 18035697; 18040685; 18045059; 18055011; 18055983; 18056003; 18059483; 18059484; 18079740; 18079966; 18081705; 18089573; 18092959; 18094555; 18158285; 18160670; 18165278; 18166783; 18166784; 18180923; 18195094; 18200037; 18216297; 18216871; 18223181; 18230964; 18239666; 18245540; 18250227; 18262227; 18270328; 18271926; 18291525; 18292125; 18294066; 18296848; 18297515; 18297539; 18301309; 18306358; 18308368; 18321571; 18326042; 18327418; 18328559; 18336541; 18343999; 18365193; 18380984; 18380991; 18398736; 18398895; 18409076; 18410451; 18426677; 18450736; 18455791; 18461004; 18464114; 18466967; 18482053; 18496561; 18503583; 18503828; 18508766; 18515659; 18519514; 18519816; 18521518; 18523665; 18528646; 18538168; 18551750; 18555525; 18566540; 18575049; 18575865; 18587010; 18587394; 18594780; 18600099; 18600100; 18600104; 18606683; 18612101; 18612778; 18616510; 18616871; 18632151; 18638010; 18641024; 18644434; 18657084; 18681311; 18692472; 18701405; 18709972; 18715806; 18720212; 18723264; 18728027; 18754026; 18755984; 18760472; 18766271; 18768782; 18769447; 18771702; 18775810; 18776170; 18781401; 18790796; 18796251; 18802948; 18805579; 18820995; 18829483; 18829531; 18838204; 18841497; 18843287; 18927438; 19003996; 19004076; 19005480; 19017763; 19042918; 19046316; 19047681; 19068216; 19074058; 19074061; 19074595; 19077438; 19080518; 19088723; 19093167; 19099657; 19105231; 19105233; 19117597; 19118011; 19120350; 19120368; 19129688; 19135773; 19136931; 19144660; 19151782; 19151790; 19153190; 19167335; 19167611; 19174256; 19175989; 19176031; 19176988; 19180571; 19181784; 19187074; 19190168; 19196872; 19208099; 19215672; 19223541; 19225136; 19229050; 19229983; 19234114; 19234192; 19234487; 19235016; 19236446; 19236761; 19249008; 19252176; 19254349; 19258483; 19258923; 19259051; 19261614; 19269737; 19273837; 19277418; 19287004; 19287382; 19287384; 19287385; 19293402; 19293426; 19299003; 19327411; 19328546; 19329339; 19336736; 19336760; 19344365; 19349617; 19350131; 19351817; 19364823; 19372714; 19375649; 19395028; 19430293; 19440215; 19446748; 19462461; 19464057; 19466975; 19470474; 19474426; 19489438; 19491085; 19500139; 19503632; 19508864; 19521067; 19531676; 19540590; 19541820; 19543316; 19544471; 19549360; 19549384; 19549399; 19549471; 19549988; 19559071; 19562618; 19562620; 19571317; 19572087; 19582452; 19589925; 19595684; 19603346; 19604093; 19604233; 19608683; 19609284; 19616600; 19629639; 19643476; 19657484; 19690956; 19698218; 19704259; 19705431; 19730683; 19734476; 19741199; 19744331; 19760754; 19772888; 19773259; 19778528; 19783980; 19799086; 19801665; 19824900; 19834108; 19847198; 19847199; 19861958; 19865112; 19877761; 19880761; 19887489; 19900702; 19903679; 19913121; 19915573; 19922437; 19929856; 19939582; 19941738; 19942343; 19950698; 19951533; 19965641; 19965650; 19965680; 20008300; 20029191; 20051435; 20061559; 20072651; 20098747; 20104275; 20109474; 20113830; 20124516; 20126644; 20128689; 20133898; 20139093; 20145151; 20151976; 20153505; 20160166; 20162546; 20171768; 20182460; 20194236; 20196786; 20203004; 20214695; 20228799; 20304805; 20304997; 20331577; 20331734; 20331763; 20336349; 20353823; 20359349; 20363735; 20379614; 20387251; 20388777; 20410924; 20417861; 20422415; 20422486; 20425335; 20425393; 20425802; 20434300; 20472827; 20472853; 20473593; 20483636; 20485371; 20489052; 20503246; 20503287; 20508616; 20520633; 20536350; 20548334; 20551270; 20556390; 20588308; 20594592; 20601445; 20615083; 20616539; 20621061; 20621720; 20627814; 20628086; 20628145; 20629097; 20631743; 20650526; 20652971; 20660330; 20667821; 20670476; 20678218; 20681956; 20691622; 20692135; 20705770; 20724918; 20728437; 20730051; 20807819; 20811399; 20861460; 20870899; 20880116; 20884719; 20888389; 20890078; 20943775; 20962278; 20962850; 20966521; 20966544; 20974963; 20980339; 21034166; 21036157; 21042281; 21068102; 21072187; 21074499; 21075308; 21082983; 21102463; 21119685; 21127060; 21138524; 21151131; 21157140; 21160067; 21169835; 21173100; 21180092; 21183952; 21198321; 21212285; 21224469; 21232003; 21235771; 21245760; 21247487; 21248298; 21273266; 21281225; 21297633; 21316606; 21325169; 21326037; 21333372; 21335558; 21347402; 21350094; 21364191; 21376394; 21382349; 21395632; 21406183; 21418908; 21421540; 21423214; 21435189; 21474922; 21484303; 21490132; 21497883; 21499015; 21502425; 21509655; 21517823; 21518725; 21537335; 21539404; 21552144; 21562050; 21569067; 21572044; 21594892; 21617012; 21620963; 21633165; 21645282; 21653937; 21660494; 21666141; 21674578; 21685469; 21685897; 21689637; 21744327; 21749449; 21750318; 21752468; 21785463; 21785467; 21786333; 21789226; 21789382; 21791467; 21798133; 21804321; 21831733; 21841788; 21859430; 21860020; 21864276; 21867614; 21885612; 21890200; 21893442; 21907792; 21912393; 21913828; 21926964; 21941370; 21953826; 21964291; 21965659; 21982959; 21988832; 22001278; 22006129; 22025110; 22035745; 22041356; 22050790; 22051730; 22065112; 22065597; 22087308; 22088920; 22109574; 22126101; 22142461; 22150289; 22161498; 22168550; 22171994; 22178881; 22185674; 22197451; 22203033; 22203487; 22205606; 22219326; 22223824; 22226123; 22251709; 22262778; 22269120; 22278696; 22286129; 22300941; 22304488; 22310976; 22313642; 22319590; 22323454; 22325365; 22334222; 22342841; 22364960; 22368272; 22369852; 22383244; 22384256; 22392353; 22397670; 22401280; 22405821; 22418850; 22461650; 22467227; 22469236; 22489043; 22523564; 22524513; 22555824; 22561633; 22565617; 22569900; 22583424; 22584586; 22592401; 22608575; 22613974; 22613986; 22641564; 22642932; 22682226; 22684105; 22696908; 22706669; 22712764; 22718845; 22722988; 22735740; 22743278; 22748021; 22762550; 22779686; 22801367; 22818858; 22820988; 22847163; 22869151; 22890406; 22898600; 22929973; 22935703; 22960131; 22987449; 23000965; 23031663; 23042399; 23047905; 23054641; 23062104; 23065274; 23108098; 23111066; 23111067; 23116358; 23121980; 23123718; 23128233; 23129323; 23130336; 23157224; 23160466; 23188718; 23193966; 23207989; 23213945; 23253862; 23266558; 23300178; 23301855; 23313484; 23337930; 23349688; 23360357; 23372669; 23376640; 23393003; 23406773; 23420150; 23430670; 23469088; 23478800; 23483208; 23531921; 23535062; 23555782; 23594705; 23622344; 23633193; 23633544; 23639951; 23652352; 23666689; 23667855; 23676499; 23677069; 23696637; 23711493; 23717640; 23818941; 23827351; 23838182; 23860450; 23863170; 23907460; 23920124; 23941832; 23984931; 23986553; 24068492; 24084459; 24085768; 24114793; 24250222; 24280222; 24416790; 24469040; 24511651 Janus kinase 2 Ensembl:ENSG00000096968 HGNC:6192 HPRD:00993 MIM:147796 Vega:OTTHUMG00000019490 JAK2 Bin Zhao, Yue Liu, Oliver He AP-1 AP1 c-Jun WEB: http://www.ncbi.nlm.nih.gov/gene JUN jun proto-oncogene 3725 1p32-p31 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000228 (EC: TAS, PMID: 10918580); GO_0000980 (EC: IDA, PMID: 19861239); GO_0001077 (EC: IEA); GO_0001102 (EC: IPI, PMID: 19861239); GO_0001190 (EC: IC, PMID: 19861239); GO_0001525 (EC: IEA); GO_0001774 (EC: IEA); GO_0001836 (EC: IEA); GO_0001889 (EC: IEA); GO_0001938 (EC: IEA); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0003151 (EC: IEA); GO_0003677 (EC: TAS, PMID: 2825349); GO_0003690 (EC: IEA); GO_0003700 (EC: IDA, PMID: 9732876); GO_0003705 (EC: IC, PMID: 19861239); GO_0003705 (EC: IDA, PMID: 2833704); GO_0003713 (EC: IDA, PMID: 2833704); GO_0005100 (EC: IDA, PMID: 11804590); GO_0005515 (EC: IPI, PMID: 10327051); GO_0005654 (EC: TAS); GO_0005667 (EC: IEA); GO_0005719 (EC: IDA, PMID: 19861239); GO_0005829 (EC: IEA); GO_0007179 (EC: IDA, PMID: 9732876); GO_0007184 (EC: IDA, PMID: 9732876); GO_0007568 (EC: IEA); GO_0007612 (EC: IEA); GO_0007623 (EC: IEA); GO_0008134 (EC: IPI, PMID: 16007074); GO_0008285 (EC: IEA); GO_0009314 (EC: IEA); GO_0009612 (EC: IEA); GO_0017053 (EC: IEA); GO_0030224 (EC: IEA); GO_0031103 (EC: IEA); GO_0031953 (EC: IEA); GO_0032321 (EC: IDA, PMID: 11804590); GO_0032496 (EC: IEA); GO_0034097 (EC: IEA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035026 (EC: IEA); GO_0035497 (EC: IDA, PMID: 19861239); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042493 (EC: IEA); GO_0042542 (EC: IEA); GO_0043392 (EC: IDA, PMID: 14645924); GO_0043524 (EC: IEA); GO_0043525 (EC: IEA); GO_0043922 (EC: IDA, PMID: 2833704); GO_0043923 (EC: IDA, PMID: 2833704); GO_0044212 (EC: IDA, PMID: 14645924); GO_0044822 (EC: IDA); GO_0045087 (EC: TAS); GO_0045657 (EC: IEA); GO_0045740 (EC: IEA); GO_0045892 (EC: IDA, PMID: 2833704); GO_0045893 (EC: IDA, PMID: 2833704); GO_0045944 (EC: IC, PMID: 19861239); GO_0045944 (EC: IDA, PMID: 2833704); GO_0048146 (EC: IEA); GO_0048661 (EC: IEA); GO_0051090 (EC: TAS); GO_0051365 (EC: IEA); GO_0051403 (EC: TAS); GO_0051591 (EC: IEA); GO_0051726 (EC: IEA); GO_0051899 (EC: IEA); GO_0060395 (EC: IDA, PMID: 9732876); GO_0070412 (EC: IPI, PMID: 9732876); GO_0071277 (EC: IEA); GO_0071837 (EC: IEA) PMID: 1310896; 1448082; 1516134; 1631061; 1651323; 1827203; 1922387; 2138276; 2320002; 2825349; 2833704; 3194415; 7623830; 7642615; 7662174; 7666555; 7690421; 7738014; 7816143; 7823959; 7848298; 7957556; 8001819; 8027667; 8087846; 8108109; 8137421; 8224842; 8302594; 8380166; 8387155; 8397339; 8440710; 8464713; 8480425; 8557686; 8570175; 8586671; 8617242; 8621542; 8621941; 8622660; 8628277; 8649793; 8654373; 8662824; 8663380; 8663478; 8733011; 8763994; 8798722; 8816797; 8816798; 8837781; 8846788; 8945519; 8974016; 8985011; 9020136; 9030721; 9129988; 9154808; 9155018; 9160889; 9207092; 9211894; 9223324; 9235954; 9334186; 9346889; 9374537; 9405416; 9443941; 9445037; 9468519; 9488446; 9510247; 9545246; 9566900; 9575168; 9621077; 9628874; 9642216; 9659924; 9670954; 9671405; 9681824; 9685505; 9692890; 9732876; 9774977; 9786917; 9808624; 9837938; 9872330; 9973222; 10026157; 10027715; 10188588; 10196196; 10207054; 10220381; 10327051; 10330159; 10346818; 10357819; 10388555; 10393177; 10419510; 10421840; 10428834; 10478848; 10488148; 10490605; 10490649; 10497212; 10506225; 10509564; 10523647; 10567391; 10567404; 10581001; 10620019; 10637231; 10644332; 10747973; 10766246; 10777532; 10788439; 10799874; 10847592; 10878360; 10903323; 10903862; 10913197; 10918580; 10962563; 10973489; 11022789; 11053448; 11090181; 11108663; 11254713; 11260070; 11274169; 11278277; 11278395; 11278640; 11278891; 11287617; 11306568; 11316804; 11331419; 11331585; 11371641; 11397794; 11431474; 11432833; 11448159; 11477071; 11479302; 11551904; 11641401; 11689449; 11704680; 11708771; 11738026; 11739718; 11801649; 11804590; 11823437; 11867732; 11877416; 11891228; 11891317; 11903046; 11909859; 11912197; 11914583; 11948398; 11956220; 11980644; 11983170; 12034730; 12052834; 12052862; 12077347; 12080089; 12087103; 12089333; 12091339; 12119282; 12145210; 12165517; 12167088; 12183893; 12185592; 12186939; 12228228; 12324474; 12419228; 12419805; 12437352; 12441106; 12446585; 12477932; 12485413; 12547826; 12554755; 12592382; 12600818; 12615916; 12618758; 12628923; 12676957; 12682910; 12692226; 12697749; 12700665; 12775419; 12788955; 12796506; 12798298; 12799614; 12805554; 12815619; 12853483; 12875982; 12909593; 12949493; 12954631; 12963547; 12963725; 12963995; 13130464; 14500675; 14506227; 14511403; 14517282; 14522952; 14530285; 14532268; 14572659; 14612408; 14630807; 14633987; 14638681; 14645224; 14645924; 14652666; 14654548; 14667575; 14675752; 14701799; 14701856; 14739464; 14973137; 15001576; 15034932; 15044437; 15087451; 15158360; 15175153; 15191540; 15226448; 15240010; 15249231; 15258149; 15262961; 15271374; 15276183; 15299005; 15302867; 15302935; 15314183; 15314185; 15319445; 15333603; 15334056; 15351693; 15378002; 15383523; 15385474; 15469925; 15480426; 15489334; 15507668; 15514030; 15528994; 15530430; 15544846; 15546613; 15550679; 15579469; 15586248; 15590691; 15626733; 15642950; 15654976; 15674337; 15677475; 15688015; 15696159; 15701643; 15702969; 15706351; 15708845; 15718494; 15746191; 15749833; 15806162; 15840658; 15863510; 15867431; 15870692; 15894171; 15897893; 15922298; 15923621; 15923644; 15936718; 15941782; 15944151; 15958389; 15991283; 15994313; 15994960; 16001969; 16007074; 16007099; 16023595; 16023596; 16045761; 16049073; 16055710; 16123044; 16140218; 16157600; 16158054; 16166642; 16179804; 16199533; 16223572; 16236267; 16243842; 16253992; 16266514; 16285957; 16289409; 16291755; 16303762; 16328781; 16341687; 16343055; 16361535; 16380075; 16410250; 16434970; 16478997; 16511568; 16533805; 16549498; 16569633; 16569638; 16571680; 16582099; 16586042; 16611996; 16620772; 16676006; 16690925; 16702224; 16710414; 16714286; 16740711; 16786139; 16824735; 16844113; 16880509; 16887814; 16895791; 16901904; 16905771; 16911523; 16916642; 16928756; 16928824; 16951171; 16980310; 16980615; 16983342; 17009014; 17056544; 17074809; 17082780; 17085440; 17088247; 17097050; 17101801; 17110928; 17121851; 17130130; 17182846; 17189706; 17215518; 17235455; 17237388; 17237407; 17283040; 17283046; 17296604; 17314269; 17317669; 17363973; 17390236; 17401435; 17403042; 17438848; 17440114; 17466952; 17495958; 17506864; 17510314; 17538020; 17588603; 17592138; 17634427; 17636030; 17637753; 17639289; 17651785; 17652081; 17658605; 17672916; 17681951; 17702894; 17703412; 17704768; 17761353; 17804415; 17845581; 17875713; 17908424; 17914574; 17920329; 17940019; 17952113; 17968316; 17978573; 18003900; 18032824; 18062835; 18065414; 18073204; 18097055; 18165900; 18171671; 18172215; 18174157; 18180292; 18180316; 18192274; 18234454; 18239671; 18253836; 18262488; 18281687; 18302882; 18304423; 18316037; 18316603; 18322962; 18347071; 18351441; 18352974; 18384814; 18410487; 18414033; 18429822; 18435914; 18443042; 18443043; 18445313; 18448277; 18467434; 18485515; 18487146; 18494816; 18497564; 18515365; 18543249; 18570890; 18572021; 18597608; 18600430; 18617512; 18619508; 18621151; 18644981; 18646516; 18650425; 18653452; 18653705; 18664273; 18671972; 18692129; 18708361; 18716056; 18725194; 18757369; 18775869; 18805449; 18823944; 18838675; 18844221; 18845538; 18922473; 18923650; 18931081; 18936204; 18940179; 18950845; 18952102; 18957410; 18957422; 18985028; 18992165; 19015316; 19018257; 19020743; 19022561; 19028685; 19035162; 19064921; 19080373; 19105933; 19123467; 19131506; 19156129; 19164581; 19165171; 19166930; 19176525; 19193763; 19206162; 19215067; 19219074; 19231233; 19238531; 19249008; 19258923; 19270716; 19281909; 19306295; 19334540; 19343052; 19357699; 19358752; 19384981; 19433309; 19435822; 19471022; 19495976; 19499154; 19513521; 19527717; 19528235; 19531482; 19578717; 19591174; 19595408; 19616043; 19653276; 19654329; 19656241; 19701800; 19714312; 19723051; 19734233; 19734545; 19738058; 19758340; 19758438; 19782465; 19787273; 19794957; 19795388; 19806201; 19811296; 19818398; 19837979; 19841138; 19859790; 19860880; 19861239; 19874574; 19878434; 19885545; 19898747; 19910471; 19910486; 19913121; 19919900; 19921846; 19937141; 19937979; 19939924; 19944700; 19959471; 19965873; 20012528; 20042607; 20044606; 20051654; 20053993; 20074357; 20093361; 20093369; 20102411; 20133937; 20137127; 20170659; 20185758; 20193273; 20195357; 20198339; 20203690; 20222112; 20225236; 20227498; 20232342; 20304822; 20306472; 20331627; 20331972; 20331980; 20333648; 20353950; 20353996; 20371606; 20376080; 20395206; 20410304; 20430872; 20432452; 20448330; 20459032; 20479273; 20479762; 20482821; 20483790; 20503287; 20505831; 20507572; 20508969; 20510020; 20511396; 20519498; 20531301; 20543003; 20554528; 20557936; 20590529; 20607803; 20619956; 20628086; 20628624; 20665665; 20680410; 20683948; 20688351; 20697347; 20698984; 20732415; 20837772; 20852630; 20936779; 20939893; 20942798; 20943203; 20952681; 20955203; 20976196; 20977688; 21030269; 21034562; 21081043; 21081472; 21106530; 21106746; 21134350; 21139048; 21145111; 21148792; 21196933; 21212516; 21268080; 21289643; 21338584; 21349840; 21350237; 21357535; 21360282; 21364631; 21381700; 21393476; 21397653; 21410405; 21417953; 21439937; 21451046; 21454713; 21496208; 21511059; 21518489; 21526160; 21530485; 21555589; 21559334; 21565167; 21570970; 21607373; 21617575; 21617851; 21640141; 21647439; 21675959; 21685329; 21693764; 21697091; 21699750; 21703547; 21732343; 21739277; 21743958; 21745629; 21799768; 21801875; 21814482; 21822357; 21829441; 21835421; 21835891; 21860413; 21862593; 21872498; 21890473; 21895606; 21937452; 21972703; 21988832; 21989944; 22001392; 22002117; 22051934; 22077140; 22083952; 22092038; 22110360; 22119392; 22132731; 22139817; 22176144; 22189957; 22235337; 22239235; 22265050; 22266871; 22271085; 22271878; 22307329; 22327296; 22328508; 22331067; 22354960; 22384197; 22384232; 22394497; 22399296; 22417306; 22429882; 22438909; 22450687; 22484283; 22508041; 22512945; 22570239; 22597534; 22675553; 22685373; 22688014; 22719067; 22749179; 22771387; 22791811; 22797068; 22801218; 22843696; 22853846; 22860098; 22869147; 22879913; 22911824; 22926518; 22933572; 22966201; 22974165; 22981541; 22988241; 23027969; 23028371; 23041974; 23047699; 23135283; 23153494; 23163821; 23182717; 23223231; 23226410; 23236059; 23269699; 23300800; 23331079; 23339184; 23362975; 23382074; 23437118; 23454483; 23467542; 23523566; 23546882; 23562910; 23580428; 23583295; 23602568; 23608488; 23614275; 23615400; 23624934; 23625009; 23625206; 23661758; 23665382; 23669365; 23671702; 23678002; 23682787; 23686163; 23690655; 23720779; 23747343; 23749999; 23762330; 23770289; 23814048; 23818969; 23832539; 23844083; 23906792; 23929433; 23942796; 24027432; 24113186 jun proto-oncogene Ensembl:ENSG00000177606 HGNC:6204 HPRD:01302 MIM:165160 Vega:OTTHUMG00000008376 JUN Bin Zhao, Yue Liu, Oliver He IPOA5 NPI-1 RCH2 SRP1 WEB: http://www.ncbi.nlm.nih.gov/gene KPNA1 karyopherin alpha 1 (importin alpha 5) 3836 3q21 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000018 (EC: TAS, PMID: 8052633); GO_0005515 (EC: IPI, PMID: 12011095); GO_0005634 (EC: IDA); GO_0005634 (EC: ISS); GO_0005643 (EC: TAS, PMID: 8052633); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0006309 (EC: TAS); GO_0006607 (EC: TAS, PMID: 7754385); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0008139 (EC: TAS, PMID: 7754385); GO_0008565 (EC: IEA); GO_0016032 (EC: TAS); GO_0019058 (EC: TAS); GO_0019221 (EC: TAS); GO_0030425 (EC: ISS); GO_0042307 (EC: ISS); GO_0075733 (EC: TAS) PMID: 1631159; 1985200; 2064827; 7494303; 7559393; 7585960; 7604027; 7745752; 7754385; 7831767; 7859280; 7892216; 8041734; 8041786; 8052633; 8105392; 8529100; 8551560; 8552640; 8619474; 8631802; 8659115; 8692858; 8707840; 8777717; 8876228; 9008157; 9020149; 9102465; 9110174; 9261351; 9275210; 9282826; 9303297; 9366553; 9436978; 9463369; 9548947; 9557700; 9562972; 9582382; 9593140; 9603322; 9695948; 9817747; 9918876; 10366569; 10473610; 10523667; 10525473; 10748034; 10772949; 10860744; 10888652; 10888660; 10951564; 10964507; 11032817; 11035935; 11060446; 11152524; 11278458; 11389849; 11682607; 11824786; 11904219; 11927559; 12011095; 12048190; 12368302; 12414950; 12477932; 12504543; 12610148; 12740372; 12783858; 12861017; 14600264; 14702039; 15037073; 15057270; 15142377; 15231748; 15342649; 15489334; 15731250; 15942031; 16135813; 16298512; 16344560; 16439554; 16698996; 16713569; 17304248; 17344301; 17353931; 17411366; 17643375; 17928350; 17938174; 17981117; 18238777; 18707546; 19001869; 19066626; 19118899; 19270695; 19338763; 19412186; 19596235; 19615732; 19801544; 19803398; 19889762; 19961612; 20015032; 20193720; 20360068; 20406804; 20705733; 20974480; 21139048; 21145461; 21209321; 21252943; 21307607; 21318276; 21326825; 21385873; 21890473; 21906983; 21963094; 21987768; 21988832; 22110766; 22130666; 22174317; 22321063; 22399302; 22422068; 22500989; 22509482; 22770219; 22778253; 22863883; 22939629; 22990118; 23000965; 23425335; 23602568; 23752268; 24163370; 24250222; 24269683 karyopherin alpha 1 (importin alpha 5) Ensembl:ENSG00000114030 HGNC:6394 HPRD:02819 MIM:600686 Vega:OTTHUMG00000159487 KPNA1 Bin Zhao, Yue Liu, Oliver He IMB1 IPO1 IPOB Impnb NTF97 WEB: http://www.ncbi.nlm.nih.gov/gene KPNB1 karyopherin (importin) beta 1 3837 17q21.32 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000060 (EC: TAS, PMID: 7615630); GO_0005515 (EC: IPI, PMID: 11311162); GO_0005634 (EC: IDA); GO_0005635 (EC: IDA); GO_0005643 (EC: TAS, PMID: 7627554); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0006309 (EC: TAS); GO_0006606 (EC: IDA, PMID: 15964792); GO_0006607 (EC: TAS, PMID: 7627554); GO_0006610 (EC: IDA, PMID: 9687515); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0008139 (EC: TAS, PMID: 7627554); GO_0008270 (EC: TAS, PMID: 7615630); GO_0008536 (EC: IEA); GO_0008565 (EC: IEA); GO_0016032 (EC: TAS); GO_0019058 (EC: TAS); GO_0019221 (EC: TAS); GO_0019899 (EC: IPI); GO_0019904 (EC: IPI, PMID: 11984006); GO_0031965 (EC: IDA); GO_0044281 (EC: TAS); GO_0044822 (EC: IDA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0071782 (EC: IDA); GO_0075733 (EC: TAS) PMID: 1631159; 1985200; 7559393; 7615630; 7627554; 8105392; 8576188; 8617226; 8617227; 8692944; 8896452; 8909533; 9045717; 9102465; 9135132; 9144189; 9214382; 9261175; 9275187; 9275210; 9323134; 9366553; 9398662; 9405152; 9430704; 9435235; 9436978; 9463369; 9562972; 9582382; 9621063; 9670026; 9687515; 9817747; 9891055; 9891056; 10037787; 10202161; 10209022; 10228156; 10353244; 10366569; 10367892; 10397761; 10473610; 10523667; 10525473; 10668806; 10749866; 10772949; 10779340; 10811646; 10822175; 10846168; 10860744; 10888652; 10929717; 10944119; 10951564; 10965137; 11024021; 11032817; 11035935; 11257130; 11266456; 11278458; 11283257; 11297531; 11310559; 11311162; 11323423; 11389849; 11401507; 11751052; 11971900; 11984006; 12011095; 12062430; 12095920; 12135354; 12176322; 12368302; 12414950; 12477932; 12504010; 12551970; 12614157; 12764225; 12783858; 12894213; 13679510; 14600264; 14718574; 15037768; 15047060; 15194443; 15231748; 15282309; 15297880; 15342649; 15383276; 15388255; 15489334; 15494309; 15572412; 15795315; 15851029; 15864302; 15870280; 15889150; 15964792; 16115628; 16196087; 16226712; 16314522; 16344560; 16354571; 16380377; 16552725; 16704975; 16982803; 17053781; 17110338; 17148452; 17172643; 17314511; 17370265; 17537211; 17573780; 17596301; 17609381; 17620599; 17643375; 17646395; 17661632; 17855385; 17916694; 17938174; 18028944; 18029348; 18051367; 18162579; 18238777; 18258596; 18398821; 18445273; 18655775; 18854154; 19056867; 19117056; 19149558; 19156129; 19275582; 19322201; 19454010; 19596686; 19738201; 19765186; 19801544; 19884259; 19925438; 20015032; 20085707; 20360068; 20462248; 20547757; 20603015; 20639865; 20658144; 20711181; 20811636; 21081666; 21139048; 21145461; 21209321; 21278340; 21319273; 21321119; 21326825; 21401918; 21625522; 21630149; 21832065; 21890473; 21900206; 21906983; 21963094; 21965294; 21987572; 22020938; 22053931; 22125623; 22145905; 22174317; 22178446; 22190364; 22222486; 22268729; 22321063; 22355797; 22415091; 22417684; 22422068; 22442722; 22500989; 22509482; 22586326; 22623428; 22863883; 22939629; 22952844; 22990118; 23000965; 23012356; 23022380; 23184937; 23246001; 23277564; 23438482; 23444224; 23455922; 23538446; 23557333; 23602568; 23798571; 23862649; 23874389; 23956138; 24132643; 24457600 karyopherin (importin) beta 1 HGNC:6400 HPRD:04114 MIM:602738 KPNB1 Bin Zhao, Yue Liu, Oliver He IPOA6 SRP6 WEB: http://www.ncbi.nlm.nih.gov/gene KPNA5 karyopherin alpha 5 (importin alpha 6) 3841 RP3-412I7.4 6q22.1 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 15057270); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0006607 (EC: TAS, PMID: 9395085); GO_0008565 (EC: IEA); GO_0019221 (EC: TAS) PMID: 1631159; 2064827; 7494303; 7566098; 7585960; 7745752; 7859280; 8041734; 8041786; 8105392; 8529100; 8551560; 8552640; 8659115; 8876228; 9008157; 9275210; 9282826; 9303297; 9366553; 9395085; 9463369; 9548947; 9557700; 9562972; 9593140; 9603322; 9918876; 10366569; 10525473; 10860744; 10888652; 10964507; 11035935; 11278458; 11389849; 11904219; 12368302; 12414950; 12477932; 12610148; 12740372; 15037073; 15057270; 16713569; 16919237; 17207965; 17411366; 17643375; 17981117; 19961612; 20015032; 20406804; 21145461; 21326825; 21460395; 21890473; 21906983; 22509482; 22939629 karyopherin alpha 5 (importin alpha 6) Ensembl:ENSG00000196911 HGNC:6398 HPRD:05179 MIM:604545 KPNA5 Bin Zhao, Yue Liu, Oliver He CD223 WEB: http://www.ncbi.nlm.nih.gov/gene LAG3 lymphocyte-activation gene 3 3902 12p13.32 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0003823 (EC: TAS, PMID: 1692078); GO_0004888 (EC: IEA); GO_0007166 (EC: IEA); GO_0009897 (EC: IEA); GO_0016021 (EC: IEA); GO_0042289 (EC: IDA, PMID: 9159144); GO_0045085 (EC: IEA); GO_0045954 (EC: IEA); GO_0050868 (EC: IEA) PMID: 1380059; 1692078; 8097522; 9159144; 9382927; 9634475; 9780176; 10545478; 11592063; 11937541; 12477932; 12775570; 12825348; 14644131; 15674389; 16519819; 16757686; 17020785; 18322184; 19773279; 20228263; 20237496; 20331378; 20385810; 20421648; 20568250; 21441454; 23261718 lymphocyte-activation gene 3 Ensembl:ENSG00000089692 HGNC:6476 HPRD:01077 MIM:153337 Vega:OTTHUMG00000169197 LAG3 Bin Zhao, Yue Liu, Oliver He LSK YT16 p56lck pp58lck WEB: http://www.ncbi.nlm.nih.gov/gene LCK lymphocyte-specific protein tyrosine kinase 3932 RP4-675E8.4 1p34.3 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000242 (EC: IDA, PMID: 7513706); GO_0000242 (EC: ISS); GO_0001772 (EC: IDA); GO_0001948 (EC: IPI, PMID: 14625311); GO_0003823 (EC: IEA); GO_0004713 (EC: EXP); GO_0004713 (EC: IDA, PMID: 214242); GO_0004713 (EC: ISS); GO_0004713 (EC: TAS); GO_0004715 (EC: IEA); GO_0004722 (EC: IDA, PMID: 8506364); GO_0004722 (EC: ISS); GO_0005515 (EC: IPI, PMID: 10209036); GO_0005524 (EC: IEA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 12150984); GO_0005886 (EC: TAS); GO_0006468 (EC: IDA, PMID: 214242); GO_0006882 (EC: IEP, PMID: 11739864); GO_0006882 (EC: ISS); GO_0006919 (EC: IDA, PMID: 16116473); GO_0006919 (EC: ISS); GO_0007173 (EC: TAS); GO_0007568 (EC: IEA); GO_0007596 (EC: TAS); GO_0008022 (EC: IPI, PMID: 16245368); GO_0008543 (EC: TAS); GO_0009612 (EC: IEA); GO_0010043 (EC: IEA); GO_0010628 (EC: IEA); GO_0016032 (EC: TAS); GO_0016311 (EC: IDA, PMID: 8506364); GO_0016311 (EC: ISS); GO_0019901 (EC: IPI, PMID: 8618896); GO_0019903 (EC: IPI); GO_0030097 (EC: NAS, PMID: 12884910); GO_0030139 (EC: IEA); GO_0030168 (EC: TAS); GO_0030217 (EC: IMP, PMID: 1579166); GO_0030217 (EC: ISS); GO_0031295 (EC: TAS); GO_0032403 (EC: IEA); GO_0038095 (EC: TAS); GO_0042169 (EC: IPI, PMID: 7852312); GO_0042169 (EC: ISS); GO_0042493 (EC: IDA, PMID: 16116473); GO_0042493 (EC: ISS); GO_0042523 (EC: IEA); GO_0042542 (EC: IEA); GO_0042609 (EC: IPI, PMID: 7486703); GO_0042610 (EC: IPI, PMID: 2470098); GO_0042802 (EC: IPI, PMID: 17118402); GO_0043548 (EC: IPI, PMID: 7504174); GO_0045087 (EC: TAS); GO_0045121 (EC: IDA, PMID: 12150984); GO_0045121 (EC: ISS); GO_0045588 (EC: IEA); GO_0046777 (EC: IEA); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0050690 (EC: TAS); GO_0050852 (EC: TAS); GO_0050853 (EC: IEA); GO_0050862 (EC: NAS, PMID: 12614355); GO_0050870 (EC: IDA, PMID: 8943371); GO_0050870 (EC: ISS); GO_0050900 (EC: TAS); GO_0051117 (EC: IPI, PMID: 15671290); GO_0051209 (EC: ISS); GO_0051249 (EC: NAS, PMID: 7852312); GO_0070062 (EC: IDA); GO_0070474 (EC: IEA); GO_2001244 (EC: IMP, PMID: 16116473); GO_2001244 (EC: ISS) PMID: 214242; 1351058; 1382070; 1385527; 1491632; 1500851; 1535086; 1535787; 1548763; 1579166; 1622897; 1638019; 1709155; 1850098; 1988541; 2014052; 2040625; 2047859; 2115123; 2470098; 2558056; 2787474; 2835736; 2850479; 3257410; 3265417; 3489486; 3493153; 7486703; 7494315; 7495859; 7504174; 7512963; 7513045; 7513706; 7522245; 7539035; 7539106; 7539724; 7543024; 7545683; 7657660; 7680610; 7682059; 7690989; 7774645; 7831289; 7852312; 7853525; 7859737; 7871751; 7896837; 7961936; 8020561; 8062594; 8077654; 8086341; 8104794; 8114715; 8139546; 8246987; 8258691; 8262984; 8294442; 8405050; 8473339; 8506364; 8551220; 8576115; 8576267; 8618896; 8626429; 8626543; 8626561; 8636141; 8648738; 8650207; 8663450; 8671590; 8692915; 8702662; 8794306; 8797825; 8798643; 8798764; 8864141; 8870842; 8871625; 8879209; 8883579; 8887682; 8900205; 8910285; 8939988; 8943371; 8945479; 8995379; 9020138; 9032261; 9036944; 9038134; 9043947; 9045636; 9047237; 9075929; 9091579; 9092949; 9121430; 9123823; 9169414; 9178760; 9178909; 9195899; 9257837; 9269777; 9312162; 9341123; 9341793; 9344703; 9403695; 9446569; 9461588; 9488700; 9573028; 9621091; 9624175; 9664084; 9685404; 9687533; 9705913; 9710204; 9712716; 9741627; 9751747; 9778343; 9788619; 9790917; 9792645; 9880255; 9973379; 9973453; 9989602; 10208934; 10209036; 10214954; 10229084; 10318843; 10330160; 10358157; 10364375; 10383400; 10422873; 10430626; 10447714; 10449731; 10455176; 10482988; 10488096; 10544125; 10553045; 10574931; 10617656; 10636863; 10642173; 10652356; 10669745; 10733577; 10748115; 10764799; 10790433; 10799545; 10799874; 10799879; 10816433; 10825200; 10858437; 10880360; 10896916; 10918587; 10921922; 10975838; 11048639; 11067948; 11075717; 11278465; 11278738; 11294838; 11294897; 11298344; 11351273; 11369760; 11381116; 11389730; 11431473; 11525746; 11572860; 11591716; 11739864; 11741599; 11741929; 11741956; 11827988; 11839738; 11854499; 11855827; 11904433; 12007789; 12036857; 12055221; 12100025; 12150984; 12171035; 12181444; 12186560; 12237775; 12359715; 12370810; 12401726; 12429743; 12468540; 12477932; 12485116; 12496362; 12527887; 12538589; 12560083; 12565834; 12570875; 12589038; 12614355; 12628756; 12637327; 12645944; 12660731; 12697812; 12732664; 12734017; 12746907; 12755691; 12817007; 12835311; 12837766; 12884910; 12899942; 12923183; 14500983; 14523017; 14534291; 14583609; 14592831; 14610044; 14623872; 14625311; 14688329; 14699120; 14702039; 14757743; 14766232; 14965316; 14993658; 15016553; 15047060; 15078178; 15085197; 15096483; 15144186; 15163734; 15186530; 15199125; 15263807; 15322115; 15331563; 15371598; 15489916; 15536084; 15554700; 15638726; 15641485; 15671290; 15687496; 15696170; 15707590; 15743820; 15751964; 15784897; 15867154; 15870274; 15892963; 15958529; 15967991; 15976924; 15980863; 16099425; 16107303; 16116473; 16185072; 16195219; 16219325; 16245368; 16257509; 16274251; 16293614; 16339550; 16344560; 16354835; 16374509; 16446405; 16461343; 16474166; 16600997; 16740747; 16769579; 16806069; 16818765; 16860758; 16888650; 16899217; 16938345; 17005671; 17008721; 17078813; 17118402; 17266559; 17382937; 17586321; 17632570; 17652306; 17897955; 17897956; 17910071; 17932036; 17998336; 18029348; 18030346; 18067320; 18314490; 18424699; 18473783; 18541536; 18683785; 18714047; 18792408; 18854243; 18991294; 19010391; 19019957; 19050260; 19109140; 19149577; 19167335; 19168706; 19192391; 19201754; 19201869; 19343496; 19439470; 19592652; 19776125; 19850743; 19912576; 20007709; 20012528; 20035083; 20040600; 20056178; 20064523; 20098747; 20237292; 20300113; 20305788; 20360068; 20372794; 20379614; 20421494; 20538612; 20541955; 20555418; 20594957; 20729329; 20835359; 20842205; 20971076; 21152094; 21234523; 21266711; 21453975; 21508261; 21738584; 21757751; 21819973; 21834013; 21900206; 21917715; 21952639; 21983898; 22034844; 22034845; 22123847; 22345475; 22378744; 22422068; 22457183; 22505724; 22537596; 22613726; 22674786; 22802418; 22863785; 22939624; 23202272; 23931554; 23946459; 24227778; 24231767 lymphocyte-specific protein tyrosine kinase Ensembl:ENSG00000182866 HGNC:6524 HPRD:01080 MIM:153390 Vega:OTTHUMG00000007463 LCK Bin Zhao, Yue Liu, Oliver He FH FHC LDLCQ2 WEB: http://www.ncbi.nlm.nih.gov/gene LDLR low density lipoprotein receptor 3949 19p13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0001523 (EC: TAS); GO_0001948 (EC: IPI, PMID: 10571240); GO_0005041 (EC: IDA, PMID: 6091915); GO_0005509 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12221107); GO_0005764 (EC: IDA, PMID: 15166224); GO_0005769 (EC: IDA, PMID: 15166224); GO_0005770 (EC: IDA, PMID: 17461796); GO_0005794 (EC: IDA, PMID: 17461796); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 6327078); GO_0005905 (EC: IDA, PMID: 15166224); GO_0006629 (EC: TAS, PMID: 10827173); GO_0006897 (EC: TAS, PMID: 12671190); GO_0006898 (EC: TAS); GO_0007603 (EC: TAS); GO_0008203 (EC: IEA); GO_0009897 (EC: IDA, PMID: 15166224); GO_0009986 (EC: IDA, PMID: 17461796); GO_0010008 (EC: TAS); GO_0010867 (EC: ISS); GO_0010899 (EC: ISS); GO_0015914 (EC: ISS); GO_0016032 (EC: IEA); GO_0030169 (EC: IEA); GO_0030229 (EC: IDA, PMID: 8626535); GO_0030299 (EC: IMP, PMID: 17142622); GO_0030301 (EC: IMP, PMID: 17142622); GO_0030669 (EC: TAS); GO_0034362 (EC: IEA); GO_0034383 (EC: IMP, PMID: 17142622); GO_0042157 (EC: TAS); GO_0042159 (EC: IEA); GO_0042632 (EC: IMP, PMID: 17142622); GO_0043235 (EC: IDA); GO_0044281 (EC: TAS); GO_0070508 (EC: ISS) PMID: 221835; 226968; 1301956; 1446662; 1464748; 1609792; 1634609; 1734722; 1757095; 1833771; 1867200; 1978682; 1999337; 2318961; 2352257; 2544509; 2569482; 2570157; 2726768; 2760198; 2760205; 2777800; 2805380; 2831865; 2837085; 2855802; 2901412; 2920733; 2988123; 3005267; 3012527; 3020025; 3104336; 3198114; 3263645; 3343347; 3549308; 3627182; 3815525; 3866240; 3924410; 3955657; 6091915; 6129958; 6291781; 6299582; 6326146; 6327078; 7550239; 7573037; 7578052; 7581403; 7583548; 7603991; 7635461; 7635482; 7649546; 7649549; 7718019; 7822276; 8096412; 8141835; 8168830; 8182149; 8300609; 8347689; 8462973; 8555255; 8626535; 8664907; 8740918; 8889549; 9016531; 9026534; 9104431; 9143924; 9222758; 9254862; 9259195; 9262405; 9265653; 9555943; 9654205; 9678702; 9733438; 9744476; 9788750; 9837937; 9852677; 10090484; 10206683; 10330445; 10380922; 10391209; 10422803; 10447263; 10571240; 10660340; 10827173; 10832106; 10882754; 10884290; 10906332; 10933493; 11050659; 11100124; 11149418; 11157985; 11173876; 11194026; 11247302; 11257257; 11298688; 11317192; 11317361; 11332639; 11453971; 11462246; 11524740; 11668627; 11668640; 11702052; 11737238; 11848618; 11849659; 11851376; 11857755; 11860839; 11916007; 11923121; 11923123; 11933210; 11947895; 11986215; 11997513; 12002911; 12009418; 12031600; 12036962; 12042130; 12048680; 12052488; 12055704; 12072496; 12082592; 12113284; 12121347; 12149270; 12165956; 12169628; 12189808; 12209363; 12221107; 12235180; 12414836; 12417285; 12442279; 12459547; 12464675; 12473254; 12473547; 12477932; 12485531; 12492446; 12493918; 12522687; 12544508; 12551936; 12562867; 12615904; 12671190; 12705331; 12716819; 12730724; 12746448; 12754519; 12810610; 12820708; 12873747; 12898587; 12901493; 12944120; 12947119; 12969990; 12975003; 14508510; 14550622; 14557872; 14568562; 14615367; 14616764; 14624402; 14739284; 14746139; 14756670; 14967814; 14993243; 15015036; 15068387; 15100232; 15133863; 15135251; 15144588; 15166224; 15172466; 15241806; 15286151; 15321837; 15321838; 15321839; 15359125; 15477777; 15489334; 15526154; 15546598; 15556092; 15585340; 15592455; 15630635; 15637307; 15665085; 15677715; 15689450; 15701167; 15741231; 15754974; 15795426; 15797858; 15823276; 15823280; 15823288; 15842735; 15863833; 15864114; 15888448; 15890894; 15899484; 15931608; 15936313; 16014965; 16015283; 16020744; 16092059; 16129683; 16159606; 16179341; 16183066; 16205024; 16257961; 16259478; 16286607; 16289238; 16335952; 16341674; 16344560; 16378661; 16389549; 16459141; 16465405; 16596945; 16608402; 16627557; 16650578; 16741934; 16750665; 16770077; 16792510; 16796766; 16806138; 16806233; 16809787; 16825289; 16828076; 16837242; 16870193; 16907851; 16920108; 16927291; 17044844; 17079229; 17090611; 17094996; 17142622; 17156886; 17170699; 17196209; 17223614; 17234631; 17239995; 17273844; 17277381; 17328821; 17335829; 17347910; 17399720; 17435765; 17445538; 17452316; 17461796; 17473053; 17517690; 17531953; 17539906; 17566095; 17607901; 17625505; 17706090; 17709443; 17766366; 17784784; 17784865; 17855807; 17889283; 17898945; 17905649; 17935672; 17964958; 17988659; 18006500; 18028451; 18065781; 18097620; 18193043; 18193044; 18206115; 18210030; 18243212; 18247305; 18261733; 18288382; 18296645; 18307033; 18317771; 18331356; 18343813; 18354102; 18355452; 18369154; 18376126; 18400033; 18513389; 18622260; 18635818; 18660489; 18660751; 18669884; 18676680; 18677035; 18685438; 18701038; 18714375; 18718593; 18757057; 18799458; 18847225; 18851860; 18936517; 18940289; 19007590; 19020990; 19056482; 19060906; 19060910; 19060911; 19062533; 19073363; 19081415; 19081568; 19087220; 19131662; 19141871; 19148283; 19148831; 19170196; 19196236; 19198609; 19208450; 19222187; 19224862; 19263529; 19318025; 19319977; 19322023; 19336370; 19336475; 19361455; 19367093; 19371225; 19411563; 19467224; 19479237; 19491387; 19520913; 19533020; 19538517; 19578796; 19583244; 19589204; 19625176; 19656773; 19667110; 19674976; 19692168; 19706701; 19717150; 19729601; 19751943; 19773416; 19811272; 19843101; 19887822; 19888660; 19906111; 19913121; 19936222; 19948739; 19948975; 19956635; 20019594; 20030366; 20031551; 20045108; 20049331; 20059631; 20065615; 20089850; 20129366; 20129369; 20144596; 20145306; 20163833; 20167577; 20172854; 20217239; 20232416; 20236128; 20308432; 20371611; 20403997; 20413733; 20416077; 20428891; 20452591; 20485444; 20498851; 20506408; 20506643; 20536507; 20538126; 20565774; 20571754; 20599862; 20602615; 20615707; 20628086; 20628808; 20634891; 20663204; 20679960; 20686565; 20691829; 20702785; 20703241; 20714348; 20734064; 20738937; 20810930; 20864672; 20962452; 20971364; 20972250; 21115573; 21139048; 21149300; 21294679; 21345210; 21377952; 21378990; 21418584; 21418831; 21457052; 21461956; 21462887; 21473855; 21511053; 21538688; 21606463; 21685362; 21692990; 21722902; 21734303; 21757058; 21763412; 21765216; 21775114; 21777527; 21829380; 21872251; 21876443; 21909108; 21909109; 21925044; 21935675; 21943158; 21947084; 21963094; 21988832; 21990180; 22003152; 22010136; 22024489; 22059152; 22074827; 22081141; 22091758; 22109552; 22128165; 22129472; 22153697; 22160468; 22190034; 22257824; 22275303; 22278734; 22286219; 22311046; 22323290; 22353362; 22378787; 22388943; 22390909; 22417841; 22425645; 22487947; 22509010; 22544571; 22554600; 22597534; 22621231; 22698793; 22716248; 22826357; 22848640; 22875854; 22910581; 22916037; 22968135; 23021490; 23022896; 23105118; 23135270; 23155708; 23162007; 23297366; 23369702; 23380588; 23382078; 23400816; 23509406; 23510778; 23535506; 23564733; 23588940; 23589850; 23593297; 23669246; 23675525; 23726366; 23733886; 23746537; 23754288; 23788249; 23957925; 24025248; 24042129; 24046328; 24144304; 24158514; 24404629; 24450200 low density lipoprotein receptor Ensembl:ENSG00000130164 HGNC:6547 HPRD:06091 MIM:606945 Vega:OTTHUMG00000171935 LDLR Bin Zhao, Yue Liu, Oliver He GAL1 GBP WEB: http://www.ncbi.nlm.nih.gov/gene LGALS1 lectin, galactoside-binding, soluble, 1 3956 22q13.1 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0001948 (EC: IEA); GO_0002317 (EC: IEA); GO_0004871 (EC: IMP, PMID: 12761501); GO_0005515 (EC: IPI, PMID: 10369126); GO_0005578 (EC: IEA); GO_0005615 (EC: IDA); GO_0005622 (EC: IDA); GO_0005634 (EC: IEA); GO_0005737 (EC: TAS, PMID: 16130169); GO_0006915 (EC: IEA); GO_0007165 (EC: IMP, PMID: 12761501); GO_0009986 (EC: IEA); GO_0010812 (EC: IEA); GO_0010977 (EC: IEA); GO_0016936 (EC: IEA); GO_0030395 (EC: IEA); GO_0031012 (EC: IDA, Qualifier: colocalizes_with); GO_0031012 (EC: ISS, Qualifier: colocalizes_with); GO_0031295 (EC: IEA); GO_0033555 (EC: IEA); GO_0034120 (EC: IEA); GO_0042493 (EC: IEA); GO_0042803 (EC: IEA); GO_0042981 (EC: TAS, PMID: 16130169); GO_0043123 (EC: IMP, PMID: 12761501); GO_0043236 (EC: IEA); GO_0044822 (EC: IDA); GO_0045445 (EC: IEA); GO_0048678 (EC: IEA); GO_0071333 (EC: IEA); GO_0071407 (EC: IEA) PMID: 1602151; 1713454; 1988031; 1996404; 2383549; 2719646; 2719964; 2910856; 3020551; 3065332; 3611046; 7501023; 7750127; 7795414; 7821789; 7869048; 8063692; 8432540; 8449510; 8872948; 9264263; 9572443; 9683529; 10369126; 10425546; 10490978; 10591208; 10642604; 10764829; 10950114; 11076863; 11146440; 11256614; 11522829; 11709720; 11846886; 11850528; 11937561; 12008046; 12125737; 12271131; 12477932; 12527107; 12615972; 12665801; 12761501; 12810474; 12823983; 12853445; 14507657; 14550305; 14612929; 14617626; 14693917; 14769876; 15050916; 15297883; 15461802; 15489334; 15489336; 15556936; 15556941; 15663199; 15690107; 15778371; 15862866; 15910247; 15929990; 15972675; 16033063; 16051185; 16130169; 16247730; 16381901; 16388708; 16530434; 16636291; 16751364; 16785517; 16818733; 16940423; 17043243; 17110462; 17177840; 17182582; 17269744; 17304502; 17353931; 17390012; 17438085; 17523619; 17535296; 17537433; 17603562; 17616672; 17649808; 17880528; 17884770; 17984174; 18007053; 18028978; 18223683; 18258591; 18292532; 18315601; 18431251; 18519761; 18570123; 18581052; 18624398; 18630998; 18633135; 18662664; 18671640; 18691335; 18791848; 18796645; 18802059; 18824694; 18838383; 18947333; 18991278; 19011096; 19032754; 19064001; 19103599; 19116313; 19125585; 19128029; 19148478; 19155496; 19171142; 19225046; 19287070; 19287997; 19363525; 19412433; 19454697; 19471022; 19492862; 19506091; 19520156; 19550395; 19561030; 19635795; 19688976; 19730683; 19738201; 19860718; 19886821; 19898636; 19900702; 19913121; 20006954; 20053628; 20157731; 20177845; 20200618; 20332322; 20360068; 20363255; 20399482; 20525878; 20549082; 20570633; 20592339; 20596638; 20628086; 20644118; 20657665; 20728947; 20816214; 20828557; 20873803; 21113146; 21122983; 21139048; 21147166; 21150319; 21191065; 21292557; 21372130; 21378323; 21385934; 21391228; 21397408; 21505194; 21514365; 21614093; 21632118; 21689853; 21724180; 21747316; 21779348; 21780106; 21807362; 21880716; 21880749; 21890473; 21897333; 21906983; 21963094; 21986812; 21998324; 22022970; 22028908; 22081313; 22155450; 22156919; 22167721; 22174828; 22267483; 22271227; 22285770; 22291012; 22353504; 22373585; 22383798; 22386573; 22432916; 22447203; 22456341; 22524424; 22546645; 22561438; 22583806; 22609846; 22623428; 22689223; 22692729; 22696230; 22716213; 22777171; 22785208; 22844466; 22863883; 22884463; 22936677; 22939629; 22939954; 22942212; 23000965; 23002109; 23022198; 23027923; 23113677; 23121677; 23124203; 23142379; 23223580; 23359172; 23389289; 23402259; 23431236; 23444403; 23510298; 23599627; 23681112; 23862649; 23929302; 23956138; 24211210 lectin, galactoside-binding, soluble, 1 Ensembl:ENSG00000100097 HGNC:6561 HPRD:01040 MIM:150570 Vega:OTTHUMG00000150661 LGALS1 Bin Zhao, Yue Liu, Oliver He HDLCQ12 HL HTGL LIPH WEB: http://www.ncbi.nlm.nih.gov/gene LIPC lipase, hepatic 3990 15q21-q23 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0004620 (EC: TAS, PMID: 3244012); GO_0004806 (EC: IDA, PMID: 182536); GO_0005615 (EC: IDA, PMID: 2839510); GO_0006633 (EC: IDA, PMID: 182536); GO_0008201 (EC: IEA); GO_0008203 (EC: IEA); GO_0019433 (EC: IDA, PMID: 182536); GO_0030169 (EC: ISS); GO_0034185 (EC: ISS); GO_0034364 (EC: IEA); GO_0034372 (EC: IDA, PMID: 8640403); GO_0034373 (EC: TAS, PMID: 2839510); GO_0034374 (EC: IMP, PMID: 3244012); GO_0034375 (EC: IMP, PMID: 3244012); GO_0034382 (EC: TAS, PMID: 9685400); GO_0034638 (EC: TAS, PMID: 2839510); GO_0042632 (EC: IMP, PMID: 1883393); GO_0043691 (EC: IC, PMID: 14531818); GO_0070328 (EC: IMP, PMID: 1883393) PMID: 182536; 1301939; 1671786; 1883393; 2324091; 2447084; 2605236; 2828141; 2839510; 3244012; 3692485; 7721852; 8640403; 8865179; 8865180; 9645503; 9685400; 10391209; 10660332; 11171287; 11181756; 11322655; 11427182; 11427226; 11454011; 11512679; 11533368; 11752456; 11916946; 11947893; 11968086; 11971936; 12006918; 12082592; 12116231; 12235167; 12354428; 12364471; 12364543; 12403660; 12417924; 12477932; 12514935; 12544508; 12547874; 12642787; 12689525; 12691171; 12700335; 12777470; 12777476; 12798568; 12818414; 12860265; 12883629; 12964943; 12966036; 14531818; 14557872; 14564687; 14585761; 14608050; 14615390; 14630921; 14650352; 14657196; 14679168; 14709367; 14967812; 14985399; 15099346; 15126514; 15135251; 15135253; 15156410; 15205216; 15292235; 15292318; 15304509; 15379569; 15608561; 15656877; 15657615; 15721010; 15755868; 15817871; 15821100; 15855254; 15941898; 15949705; 15961789; 15979432; 15983229; 15983323; 16005462; 16030523; 16038892; 16039291; 16077949; 16115483; 16122151; 16141008; 16153627; 16164573; 16205020; 16316842; 16324926; 16330034; 16338252; 16343038; 16419358; 16427731; 16449872; 16542392; 16554020; 16570154; 16603721; 16770077; 16793047; 16822236; 16879193; 16928730; 17080261; 17137217; 17157861; 17175070; 17222414; 17234195; 17318300; 17327141; 17342071; 17390085; 17399967; 17406067; 17428321; 17440012; 17537154; 17568951; 17700364; 17855807; 17919884; 18001531; 18059528; 18084291; 18160998; 18164013; 18193043; 18193044; 18249219; 18275964; 18354102; 18364377; 18413186; 18468200; 18510853; 18513389; 18592285; 18599739; 18622260; 18636124; 18641720; 18660489; 18675312; 18676680; 18724972; 18758746; 18927546; 18978678; 18996102; 19034316; 19043545; 19052449; 19056482; 19060906; 19060910; 19060911; 19088157; 19101670; 19131662; 19136429; 19148283; 19155102; 19155782; 19170196; 19263529; 19285487; 19336370; 19350521; 19367320; 19420105; 19428034; 19429860; 19479237; 19489872; 19528346; 19534808; 19558527; 19578796; 19625176; 19656773; 19689828; 19691831; 19692168; 19695855; 19729601; 19734193; 19773416; 19783858; 19810818; 19876004; 19878569; 19913121; 19936222; 20031551; 20125193; 20139978; 20160193; 20167577; 20186155; 20222961; 20373033; 20384434; 20385819; 20385826; 20400780; 20403997; 20430392; 20444273; 20452482; 20492333; 20536507; 20565774; 20595410; 20602615; 20628086; 20634891; 20673868; 20679960; 20682687; 20686565; 20691829; 20822508; 20851298; 20855565; 20864672; 20888482; 21139980; 21189265; 21252145; 21261091; 21352420; 21371711; 21386085; 21447678; 21548985; 21665990; 21750705; 21943158; 21960661; 21986251; 21988832; 22047520; 22073289; 22262398; 22286219; 22294764; 22359512; 22385360; 22399527; 22449147; 22464213; 22916037; 22935046; 23144319; 23181436; 23222517; 23251661; 23281178; 23343765; 23348725; 23351562; 23455636; 23457133; 23505323; 23535033; 23874450; 24023260 lipase, hepatic Ensembl:ENSG00000166035 HGNC:6619 HPRD:01058 MIM:151670 Vega:OTTHUMG00000132632 LIPC Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene LOX lysyl oxidase 4015 5q23.2 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0001568 (EC: IEA); GO_0004720 (EC: IEA); GO_0005507 (EC: IEA); GO_0005515 (EC: IPI, PMID: 19570982); GO_0005576 (EC: TAS); GO_0005581 (EC: IEA); GO_0005615 (EC: IEA); GO_0005634 (EC: IEA); GO_0006464 (EC: TAS, PMID: 1685472); GO_0030198 (EC: TAS); GO_0030199 (EC: IEA); GO_0030324 (EC: IEA); GO_0042060 (EC: IEA); GO_0042493 (EC: IEA); GO_0048251 (EC: IEA); GO_0048545 (EC: IEA) PMID: 1352776; 1357535; 1683640; 1685472; 2863189; 2874833; 3120785; 6127904; 6144680; 6147899; 6912069; 7706256; 7902322; 8082810; 8100215; 8442432; 8636146; 9111998; 10391127; 11642359; 11675877; 11807790; 11916256; 12101112; 12452073; 12477932; 12577300; 12686141; 12750963; 12820424; 15110773; 15137057; 15146197; 15273433; 15374948; 15489334; 15609325; 15843371; 16023247; 16251195; 16344560; 16357151; 16440329; 16533769; 16642001; 17395448; 17616686; 17673218; 17849172; 18566459; 18764858; 19020742; 19029090; 19087518; 19111879; 19394199; 19406911; 19526206; 19570982; 19583806; 19654310; 19661442; 19667273; 19724858; 19816945; 20026874; 20146053; 20179655; 20379614; 20453000; 20498644; 20689807; 20717923; 20812961; 20929399; 20956321; 21215756; 21239473; 21282564; 21306648; 21318022; 21532881; 21536655; 21546528; 21565611; 21575462; 21612403; 21740577; 21995629; 22438909; 22533780; 22722997; 22767499; 22824984; 22883193; 22948781; 22966818; 22994786; 23165370; 23188504; 23262025; 23267843; 23357697; 23400010; 23413043; 23413430; 23494965; 23530115; 23545606; 23560895; 23619422; 23667531; 23886186; 24113189; 24167568 lysyl oxidase LOX Bin Zhao, Yue Liu, Oliver He HDLCQ11 LIPD WEB: http://www.ncbi.nlm.nih.gov/gene LPL lipoprotein lipase 4023 8p22 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0001523 (EC: TAS); GO_0004465 (EC: IDA, PMID: 3973011); GO_0004465 (EC: ISS, PMID: 10727238); GO_0004620 (EC: ISS, PMID: 10727238); GO_0004806 (EC: IDA, PMID: 12573449); GO_0004806 (EC: ISS, PMID: 10727238); GO_0005102 (EC: IPI, PMID: 10085125); GO_0005515 (EC: IPI); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 12573449); GO_0005886 (EC: IEA); GO_0006633 (EC: IC, PMID: 3973011); GO_0006633 (EC: IDA, PMID: 182536); GO_0006633 (EC: ISS); GO_0006641 (EC: ISS, PMID: 10727238); GO_0006644 (EC: ISS, PMID: 10727238); GO_0007603 (EC: TAS); GO_0008201 (EC: IDA, PMID: 12573449); GO_0009409 (EC: IEA); GO_0009986 (EC: IEA); GO_0010744 (EC: IC, PMID: 12573449); GO_0010886 (EC: IMP, PMID: 12573449); GO_0010890 (EC: IMP, PMID: 12573449); GO_0017129 (EC: IEA); GO_0019432 (EC: IEA); GO_0019433 (EC: IDA, PMID: 182536); GO_0019433 (EC: ISS); GO_0031012 (EC: IEA); GO_0031225 (EC: IEA); GO_0034185 (EC: IPI, PMID: 15178420); GO_0034361 (EC: IEA); GO_0034371 (EC: IC, PMID: 3973011); GO_0034372 (EC: IDA, PMID: 3973011); GO_0034372 (EC: ISS); GO_0042157 (EC: TAS); GO_0042493 (EC: IEA); GO_0042627 (EC: IEA); GO_0044281 (EC: TAS); GO_0070328 (EC: IGI, PMID: 17018885) PMID: 182536; 1281473; 1371284; 1400331; 1406652; 1479292; 1511985; 1521525; 1537564; 1576758; 1598907; 1619366; 1639392; 1674945; 1702428; 1730727; 1731801; 1737848; 1752947; 1907278; 1969408; 1975597; 2010533; 2038366; 2110364; 2121025; 2243796; 2294743; 2340307; 2349938; 2536938; 2701938; 3355847; 3515966; 3692485; 3823907; 3973011; 7510694; 7592875; 7647785; 7686151; 7713910; 7753827; 7806969; 7818530; 7906986; 7989348; 8096693; 8125298; 8135797; 8144523; 8288243; 8301230; 8308035; 8325986; 8449037; 8486765; 8567671; 8956048; 9183545; 9298816; 9374130; 9401010; 9430364; 9519338; 9662394; 9719626; 10085125; 10391209; 10660334; 10727238; 11073182; 11096142; 11126401; 11132601; 11140837; 11171287; 11194013; 11205691; 11229437; 11284423; 11316129; 11341749; 11395037; 11427211; 11441189; 11484171; 11500192; 11533368; 11534394; 11579204; 11593500; 11605530; 11680797; 11683775; 11702052; 11702219; 11711487; 11714857; 11714860; 11730816; 11796707; 11796709; 11834518; 11852057; 11893776; 11893778; 11897170; 11899831; 11921083; 11947965; 11996946; 12042669; 12044583; 12082592; 12107736; 12117735; 12133533; 12133567; 12164879; 12174215; 12208477; 12226739; 12230584; 12370850; 12408999; 12446192; 12477932; 12483461; 12501246; 12514935; 12544508; 12573449; 12636935; 12647273; 12655575; 12679477; 12687649; 12690214; 12701046; 12704407; 12708905; 12732844; 12740382; 12746411; 12747600; 12755701; 12777470; 12782148; 12793009; 12818414; 12862202; 12865761; 12866915; 12876415; 12889841; 12905705; 12915220; 12919138; 12964943; 12966036; 14553962; 14564687; 14570890; 14580156; 14580165; 14581156; 14660566; 14669227; 14693718; 14702039; 14764824; 14967813; 14984315; 14988233; 14988305; 15019539; 15051515; 15060087; 15076187; 15115692; 15127290; 15135251; 15155715; 15178420; 15189363; 15202783; 15221136; 15253101; 15256516; 15257172; 15270617; 15292370; 15292372; 15331147; 15356086; 15386377; 15489334; 15543643; 15545743; 15562208; 15608561; 15637076; 15657615; 15696473; 15699916; 15721013; 15749185; 15764642; 15793775; 15795426; 15802535; 15857159; 15858619; 15878772; 15896905; 15928243; 15939061; 15961789; 15979432; 15994321; 16013913; 16015281; 16029634; 16030523; 16086925; 16106048; 16122151; 16132104; 16135440; 16141008; 16142021; 16168296; 16169070; 16179346; 16195478; 16205020; 16253639; 16256241; 16343038; 16344560; 16353345; 16357806; 16364275; 16369102; 16378107; 16416313; 16418216; 16419488; 16430904; 16431216; 16446009; 16449872; 16451134; 16460718; 16466345; 16517593; 16519597; 16534528; 16542392; 16544732; 16552397; 16630553; 16635607; 16651467; 16702309; 16741292; 16755277; 16763159; 16770077; 16776623; 16799404; 16813599; 16822320; 16829344; 16837242; 16840197; 16864937; 16894468; 16896939; 16926441; 16928730; 16965549; 16989840; 17001213; 17006673; 17018885; 17029199; 17032721; 17058522; 17072956; 17093291; 17130180; 17137217; 17157861; 17163816; 17244606; 17291198; 17299085; 17299379; 17311894; 17318300; 17328917; 17342071; 17347923; 17356047; 17374417; 17428620; 17436307; 17463246; 17473385; 17476032; 17484619; 17487735; 17517063; 17533471; 17535427; 17555736; 17560523; 17562973; 17568951; 17587400; 17615573; 17620184; 17644777; 17652898; 17653444; 17662793; 17681919; 17700364; 17705673; 17706445; 17717288; 17721767; 17726453; 17727701; 17761930; 17803213; 17848837; 17855807; 17903299; 17919884; 17939375; 17997385; 18020971; 18068174; 18175800; 18187430; 18187620; 18193043; 18193044; 18193046; 18223635; 18242618; 18275685; 18275964; 18321693; 18325076; 18336668; 18354102; 18449420; 18454146; 18494281; 18513389; 18534873; 18535540; 18590804; 18596051; 18603820; 18616755; 18619685; 18635818; 18636124; 18649389; 18660489; 18676680; 18681781; 18693040; 18724972; 18821565; 18823627; 18922999; 18927546; 18985010; 18986377; 18996102; 19004026; 19018513; 19028676; 19034041; 19034316; 19052449; 19060906; 19060910; 19060911; 19099922; 19131662; 19148283; 19155782; 19167106; 19170196; 19185650; 19191728; 19207029; 19246456; 19254215; 19259048; 19295657; 19299407; 19335919; 19336370; 19336475; 19340428; 19357293; 19367093; 19367320; 19368142; 19403283; 19420105; 19428034; 19471043; 19479237; 19489872; 19501493; 19534808; 19542565; 19556723; 19558660; 19563912; 19578796; 19584682; 19596235; 19602472; 19625176; 19629056; 19642912; 19656773; 19664517; 19689828; 19692168; 19709746; 19729601; 19766899; 19772655; 19773416; 19780863; 19783858; 19818126; 19834535; 19875996; 19878569; 19884647; 19888660; 19899640; 19910634; 19913121; 19936222; 19948975; 19956635; 20031538; 20031551; 20031591; 20075597; 20092038; 20099167; 20108206; 20139978; 20150529; 20160193; 20167577; 20228263; 20235787; 20301485; 20347446; 20350420; 20385819; 20400780; 20403997; 20410100; 20416077; 20421589; 20429872; 20430250; 20430392; 20452482; 20506644; 20536507; 20538960; 20565774; 20571754; 20581395; 20588308; 20595410; 20596061; 20602615; 20616609; 20628086; 20634891; 20650961; 20657596; 20673868; 20679960; 20686565; 20691829; 20693566; 20694148; 20712903; 20714348; 20836743; 20855565; 20864672; 20926921; 20929345; 20943490; 21044743; 21060192; 21127884; 21139048; 21145461; 21146168; 21159338; 21162862; 21193198; 21252145; 21252727; 21385844; 21386085; 21398697; 21419757; 21448664; 21478160; 21499891; 21508119; 21518912; 21621348; 21722517; 21816453; 21832049; 21840003; 21854610; 21862952; 21909109; 21943158; 21966368; 21978733; 21980507; 21988832; 22018640; 22078753; 22095987; 22101375; 22123668; 22171074; 22239554; 22244040; 22286219; 22368174; 22399527; 22541364; 22729917; 22772754; 22773878; 22810051; 22820186; 22828442; 22916037; 23008484; 23056264; 23089926; 23320821; 23344322; 23377670; 23478142; 23505323; 23614796; 23623643; 23661675; 23726366; 23735640; 23761384; 23880163; 23902956; 24004859; 24009459; 24023261; 24121499; 24308220; 24340925 lipoprotein lipase Ensembl:ENSG00000175445 HGNC:6677 HPRD:01999 MIM:609708 Vega:OTTHUMG00000036645 LPL Bin Zhao, Yue Liu, Oliver He A2MR APOER APR CD91 IGFBP3R LRP LRP1A TGFBR5 WEB: http://www.ncbi.nlm.nih.gov/gene LRP1 low density lipoprotein receptor-related protein 1 4035 12q13.3 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0001523 (EC: TAS); GO_0002020 (EC: IEA); GO_0004872 (EC: TAS, PMID: 10880251); GO_0005509 (EC: ISS); GO_0005515 (EC: IPI, PMID: 17326667); GO_0005634 (EC: IEA); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005768 (EC: IEA); GO_0005886 (EC: TAS); GO_0005887 (EC: ISS); GO_0005905 (EC: IEA); GO_0006898 (EC: IEA); GO_0007205 (EC: IEA); GO_0007568 (EC: IEA); GO_0007603 (EC: TAS); GO_0008203 (EC: IEA); GO_0008283 (EC: IEA); GO_0010875 (EC: ISS); GO_0014912 (EC: ISS); GO_0030136 (EC: IEA); GO_0030178 (EC: ISS); GO_0030425 (EC: IEA); GO_0030666 (EC: TAS); GO_0032370 (EC: ISS); GO_0032374 (EC: ISS); GO_0032403 (EC: IDA, PMID: 8626514); GO_0032429 (EC: ISS); GO_0032956 (EC: ISS); GO_0034185 (EC: IDA, PMID: 2779654); GO_0034185 (EC: IPI, PMID: 18635818); GO_0035909 (EC: ISS); GO_0042157 (EC: IEA); GO_0042953 (EC: NAS, PMID: 3266596); GO_0042954 (EC: NAS, PMID: 3266596); GO_0043025 (EC: IEA); GO_0043235 (EC: IDA); GO_0043277 (EC: ISS); GO_0043524 (EC: IEA); GO_0044822 (EC: IDA); GO_0051222 (EC: IEA); GO_0070325 (EC: IC, PMID: 18635818); GO_0097242 (EC: TAS, PMID: 19098903); GO_2000587 (EC: ISS) PMID: 1281473; 1374383; 1377168; 1423505; 1464627; 1502153; 1698775; 1702392; 1718973; 2112085; 2548950; 2597675; 2779654; 3266596; 7508685; 7510694; 7534747; 7543026; 7721852; 7775583; 7961982; 7989348; 8307199; 8546712; 8626514; 8703036; 8806749; 9045712; 9045716; 9051770; 9252371; 9295345; 9782078; 9804823; 9820815; 9837937; 10318830; 10471328; 10514495; 10608878; 10632583; 10652313; 10747918; 10772929; 10827173; 10880251; 11006321; 11076057; 11100124; 11158305; 11247302; 11248808; 11279011; 11359936; 11421580; 11436125; 11479307; 11560994; 11600564; 11705989; 11720768; 11729193; 11823454; 11854294; 11861214; 11867643; 11907044; 11931574; 11992244; 12069755; 12169628; 12194978; 12212791; 12393177; 12394648; 12402342; 12412500; 12417024; 12473559; 12477932; 12522143; 12522212; 12531796; 12555245; 12637503; 12672816; 12713657; 12732394; 12750160; 12789267; 12793904; 12807892; 12821648; 12857755; 12888553; 12960961; 14585398; 14593097; 14597676; 14645246; 14699139; 14702039; 14739301; 14980518; 14991768; 15001579; 15044004; 15048651; 15131125; 15135046; 15226301; 15231748; 15264223; 15272003; 15288502; 15294142; 15328156; 15591119; 15634227; 15647823; 15705569; 15705932; 15749709; 15769472; 15772078; 15800028; 15863833; 15925094; 15944146; 16040006; 16088940; 16102056; 16167883; 16175004; 16328515; 16335952; 16362633; 16402284; 16407289; 16459332; 16567404; 16606588; 16697011; 16697675; 16751776; 16807059; 16821592; 16839343; 16929535; 16956829; 17012232; 17124247; 17155964; 17203175; 17258834; 17326667; 17360663; 17570828; 17620659; 17694066; 17709443; 17711877; 17889283; 17897319; 17908054; 17942912; 17974965; 18037995; 18156630; 18166789; 18194421; 18231792; 18277139; 18281370; 18288927; 18317248; 18321860; 18373737; 18381291; 18489712; 18635818; 18648652; 18653767; 18683150; 18685438; 18706476; 18834984; 18940800; 18941243; 18990694; 19008962; 19036715; 19036954; 19098903; 19105203; 19176371; 19251705; 19299462; 19336475; 19383717; 19393132; 19420105; 19439404; 19446849; 19615732; 19631509; 19664312; 19665999; 19684401; 19795391; 19815552; 19823686; 19885591; 19913121; 19948975; 19968964; 20048078; 20101615; 20167577; 20205790; 20220145; 20381197; 20468060; 20472562; 20535486; 20558745; 20568118; 20610799; 20628086; 20637261; 20644732; 20685197; 20686565; 20716178; 20826454; 20869432; 20980003; 21054788; 21078624; 21139048; 21165580; 21212259; 21325077; 21383009; 21391865; 21408136; 21454812; 21471105; 21496869; 21518850; 21610072; 21650223; 21666692; 21671167; 21676498; 21676865; 21946350; 21951552; 21966368; 21968187; 22027013; 22034896; 22055160; 22072275; 22081071; 22238606; 22268729; 22298529; 22347399; 22392894; 22412921; 22427881; 22454511; 22467855; 22534531; 22683712; 22711991; 22817990; 22819221; 22822085; 22873206; 22914594; 22967844; 23064555; 23166318; 23167255; 23186781; 23228658; 23241409; 23264627; 23284291; 23386606; 23386614; 23404896; 23425335; 23498137; 23640058; 23675525; 23755898; 23793025; 23898049; 23922991; 23936774; 23959870; 24054777; 24072693; 24126057; 24129569; 24139096 low density lipoprotein receptor-related protein 1 Ensembl:ENSG00000123384 HGNC:6692 HPRD:00138 MIM:107770 Vega:OTTHUMG00000044412 LRP1 Bin Zhao, Yue Liu, Oliver He ADCAD2 WEB: http://www.ncbi.nlm.nih.gov/gene LRP6 low density lipoprotein receptor-related protein 6 4040 12p13.2 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0001702 (EC: IBA); GO_0001843 (EC: IBA); GO_0001933 (EC: IMP, PMID: 16365045); GO_0001947 (EC: IEA); GO_0002053 (EC: IEA); GO_0003344 (EC: IBA); GO_0005041 (EC: IDA, PMID: 16263759); GO_0005102 (EC: IPI, PMID: 14739301); GO_0005109 (EC: IPI, PMID: 11029007); GO_0005515 (EC: IPI, PMID: 11029007); GO_0005769 (EC: IDA, Qualifier: colocalizes_with, PMID: 16890161); GO_0005783 (EC: IEA); GO_0005794 (EC: IDA, Qualifier: colocalizes_with, PMID: 16890161); GO_0005886 (EC: IDA, PMID: 16263759); GO_0005901 (EC: IDA, Qualifier: colocalizes_with, PMID: 16890161); GO_0006469 (EC: IMP, PMID: 16365045); GO_0007204 (EC: IEA); GO_0007268 (EC: IBA); GO_0009880 (EC: IBA); GO_0009952 (EC: IBA); GO_0009986 (EC: IDA, PMID: 12897152); GO_0014029 (EC: IDA, PMID: 11029007); GO_0014033 (EC: IDA, PMID: 11029007); GO_0016021 (EC: IEA); GO_0016055 (EC: IDA, PMID: 16263759); GO_0016055 (EC: IMP, PMID: 11029007); GO_0016337 (EC: IEA); GO_0017147 (EC: IPI, PMID: 11029007); GO_0019210 (EC: IMP, PMID: 16365045); GO_0019534 (EC: IMP, PMID: 16564009); GO_0019534 (EC: IMP, Qualifier: NOT, PMID: 18350154); GO_0021587 (EC: IBA); GO_0021794 (EC: IBA); GO_0021795 (EC: IEA); GO_0021861 (EC: IEA); GO_0021874 (EC: IEA); GO_0021943 (EC: IEA); GO_0021987 (EC: IBA); GO_0030278 (EC: IBA); GO_0030326 (EC: IBA); GO_0030901 (EC: IBA); GO_0030917 (EC: IBA); GO_0031410 (EC: IDA, PMID: 16890161); GO_0034185 (EC: IBA); GO_0034392 (EC: IMP, PMID: 15271658); GO_0035115 (EC: IEA); GO_0035116 (EC: IEA); GO_0035261 (EC: IBA); GO_0036342 (EC: IEA); GO_0042074 (EC: IEA); GO_0042475 (EC: IBA); GO_0042733 (EC: IEA); GO_0042803 (EC: IPI, PMID: 12897152); GO_0042813 (EC: IBA); GO_0043025 (EC: IBA); GO_0043065 (EC: IEA); GO_0043235 (EC: IBA); GO_0043434 (EC: IEA); GO_0044332 (EC: IDA, PMID: 11029007); GO_0044335 (EC: IC, PMID: 11029007); GO_0044340 (EC: IC, PMID: 15271658); GO_0045202 (EC: IBA); GO_0045598 (EC: IBA); GO_0045599 (EC: IEA); GO_0045778 (EC: IEA); GO_0045780 (EC: IEA); GO_0045787 (EC: IMP, PMID: 15271658); GO_0045893 (EC: IMP, PMID: 18215320); GO_0045944 (EC: IDA, PMID: 12857724); GO_0046849 (EC: IBA); GO_0048596 (EC: IBA); GO_0050680 (EC: IEA); GO_0051091 (EC: IDA, PMID: 14739301); GO_0051593 (EC: IEA); GO_0060021 (EC: IBA); GO_0060026 (EC: IBA); GO_0060059 (EC: IBA); GO_0060070 (EC: IDA, PMID: 12121999); GO_0060070 (EC: IMP, PMID: 18215320); GO_0060284 (EC: IEA); GO_0060325 (EC: IBA); GO_0060349 (EC: IBA); GO_0060444 (EC: IBA); GO_0060535 (EC: IBA); GO_0060596 (EC: IEA); GO_0061310 (EC: IEA); GO_0061324 (EC: IEA); GO_0071397 (EC: IMP, PMID: 16890161); GO_0071542 (EC: IEA); GO_0071901 (EC: IDA, PMID: 19107203); GO_0071936 (EC: IDA, PMID: 11029007); GO_0090009 (EC: IBA); GO_0090118 (EC: IBA); GO_0090244 (EC: IBA); GO_0090245 (EC: IBA); GO_0090263 (EC: IDA, PMID: 11448771); GO_1901998 (EC: IMP, PMID: 16564009); GO_2000055 (EC: IDA, PMID: 15908424); GO_2000149 (EC: IEA); GO_2000151 (EC: IEA); GO_2000162 (EC: IEA); GO_2000164 (EC: IEA); GO_2000166 (EC: IEA); GO_2000168 (EC: IEA) PMID: 8889549; 9704021; 10036184; 11029007; 11357136; 11448771; 11742004; 12121999; 12477932; 12581525; 12857724; 12897152; 14702039; 14739301; 15035989; 15084453; 15271658; 15342556; 15469977; 15489334; 15516984; 15908424; 16263759; 16355283; 16365045; 16384981; 16513652; 16543246; 16564009; 16815997; 16890161; 16989816; 17326769; 17332414; 17376403; 17517621; 17569865; 17698587; 17765217; 17804805; 18077588; 18083125; 18215320; 18350154; 18362152; 18378904; 18406176; 18493104; 18502762; 18505732; 18524778; 18606139; 18676680; 18717822; 18762581; 18772438; 18838381; 18948618; 18981475; 19015224; 19107203; 19170196; 19293931; 19339249; 19453261; 19477926; 19625176; 19667113; 19692168; 19711366; 19801552; 19833493; 19881541; 19898734; 19910923; 19913121; 20053636; 20057906; 20093360; 20128690; 20137080; 20194742; 20227366; 20351274; 20388731; 20390408; 20460648; 20543981; 20628086; 20676368; 20846389; 20926594; 20974802; 21139048; 21245321; 21397183; 21536646; 21887268; 21906983; 21944579; 21963094; 21984209; 22000855; 22000856; 22128165; 22372892; 22393312; 22490400; 22570728; 22575959; 22589387; 22606268; 22645275; 22682247; 22696217; 22871567; 22899650; 22907437; 23000965; 23077088; 23218566; 23302227; 23306204; 23395167; 23638027; 23666756; 23703864; 23754096; 23811937; 23870195; 23959799; 23987510 low density lipoprotein receptor-related protein 6 Ensembl:ENSG00000070018 HGNC:6698 HPRD:04617 MIM:603507 Vega:OTTHUMG00000168540 LRP6 Bin Zhao, Yue Liu, Oliver He AU CD239 LU MSK19 WEB: http://www.ncbi.nlm.nih.gov/gene BCAM basal cell adhesion molecule (Lutheran blood group) 4059 19q13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0004888 (EC: TAS, PMID: 7777537); GO_0005055 (EC: IMP, PMID: 16236823); GO_0005886 (EC: TAS, PMID: 9166867); GO_0005887 (EC: TAS, PMID: 7777537); GO_0007155 (EC: TAS, PMID: 7954395); GO_0007160 (EC: IMP, PMID: 16236823); GO_0007165 (EC: TAS, PMID: 7777537); GO_0009897 (EC: IC, PMID: 16236823); GO_0043236 (EC: IMP, PMID: 16236823); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 2907851; 3810828; 7777537; 7954395; 8781446; 8889548; 9166867; 9192786; 9642222; 11133776; 11319237; 12244066; 12477932; 12493773; 12754519; 14641871; 14755370; 15238148; 15278364; 15342556; 15489334; 15790807; 16236823; 16335952; 16584446; 17087659; 17638854; 18067501; 18302987; 18510579; 18514010; 18635166; 18815288; 18972067; 19056867; 19065527; 19201739; 19667067; 20370913; 20562314; 20566895; 20655789; 21139048; 21434869; 21858073; 22404936; 22941965; 23001842; 23125034; 23160466; 23168236; 23192594; 23406016; 23421542; 24036115 basal cell adhesion molecule (Lutheran blood group) Ensembl:ENSG00000187244 HGNC:6722 HPRD:00197 MIM:612773 Vega:OTTHUMG00000180838 BCAM Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene MAOB monoamine oxidase B 4129 RP1-201D17__B.1 Xp11.23 20140408 9606 X protein-coding Official from a nomenclature committee GO_0005739 (EC: IDA); GO_0005740 (EC: TAS, PMID: 7063850); GO_0005741 (EC: TAS); GO_0005743 (EC: IEA); GO_0006805 (EC: TAS); GO_0008131 (EC: TAS); GO_0009055 (EC: TAS, PMID: 8602220); GO_0009636 (EC: IEA); GO_0010044 (EC: IEA); GO_0010269 (EC: IEA); GO_0014063 (EC: IEA); GO_0016021 (EC: IEA); GO_0021762 (EC: IEP); GO_0032496 (EC: IEA); GO_0042493 (EC: IEA); GO_0042803 (EC: IEA); GO_0044281 (EC: TAS); GO_0045471 (EC: IEA); GO_0045964 (EC: IEA); GO_0050660 (EC: IEA); GO_0051412 (EC: IEA) PMID: 1432104; 2023912; 3387449; 3540317; 4016087; 4687789; 6951409; 7063850; 7499273; 8060341; 8316221; 8515265; 8602220; 8613523; 8665924; 8889548; 9045087; 9596006; 10653595; 11049757; 11171904; 11295131; 11396715; 11753429; 11761322; 11861643; 11956220; 12011284; 12098640; 12136060; 12360111; 12428723; 12465073; 12477932; 12563176; 12732844; 12763335; 12777388; 12815660; 12815741; 12825788; 12855685; 12913124; 12963742; 14659989; 14697881; 14743364; 14962671; 15024015; 15027868; 15028609; 15057517; 15211623; 15247489; 15261699; 15355491; 15461973; 15589121; 15694196; 15699372; 15710600; 15753616; 15772651; 15862518; 15921854; 15955630; 16129825; 16344560; 16366596; 16427095; 16455660; 16484337; 16610949; 16674552; 16807522; 17044053; 17270484; 17289152; 17427196; 17449559; 17628790; 17640790; 17885758; 17918234; 17938636; 18092818; 18205889; 18270970; 18327668; 18405071; 18430257; 18553363; 18832861; 19053775; 19058789; 19086053; 19156168; 19221690; 19268543; 19455600; 19506579; 19598235; 19657584; 19693267; 19789505; 19863190; 19874574; 19913121; 19956754; 20022119; 20127808; 20461808; 20467438; 20479760; 20485326; 20589923; 20603187; 20628086; 20648649; 20734064; 21075085; 21177257; 21359973; 21610556; 21781348; 21786798; 21906983; 21971000; 21971001; 21978362; 21978760; 21988832; 22270014; 22414661; 22974659; 23054588; 23093014; 23319194; 23474901 monoamine oxidase B MAOB Bin Zhao, Yue Liu, Oliver He DDPAC FTDP-17 MAPTL MSTD MTBT1 MTBT2 PPND TAU WEB: http://www.ncbi.nlm.nih.gov/gene MAPT microtubule-associated protein tau 4137 17q21.1 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000226 (EC: IDA, PMID: 1057175); GO_0001764 (EC: IEA); GO_0005200 (EC: TAS, PMID: 2498079); GO_0005515 (EC: IPI, PMID: 10987820); GO_0005829 (EC: TAS); GO_0005874 (EC: IEA); GO_0005875 (EC: TAS, PMID: 10747907); GO_0005886 (EC: IDA, PMID: 8522593); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0007628 (EC: IEA); GO_0008017 (EC: IDA, PMID: 1918161); GO_0008088 (EC: IEA); GO_0010506 (EC: IGI, PMID: 19074461); GO_0017124 (EC: IPI, PMID: 9763511); GO_0019899 (EC: IPI, PMID: 12888622); GO_0019901 (EC: IEA); GO_0030424 (EC: IDA, PMID: 8642405); GO_0030426 (EC: IDA, PMID: 8642405); GO_0031113 (EC: NAS, PMID: 1057175); GO_0031116 (EC: IDA, PMID: 1421571); GO_0032387 (EC: IEA); GO_0034185 (EC: IPI, PMID: 7566652); GO_0034399 (EC: IDA, PMID: 19157893); GO_0045298 (EC: IDA, PMID: 8642405); GO_0045773 (EC: IDA, PMID: 1389180); GO_0047497 (EC: IEA); GO_0048675 (EC: IEA); GO_0048699 (EC: NAS, PMID: 8522593); GO_0060632 (EC: IEA); GO_0071813 (EC: IPI, PMID: 7972031) PMID: 1057175; 1181841; 1330687; 1389180; 1420178; 1421571; 1512244; 1713721; 1723470; 1915258; 1918161; 2123288; 2484340; 2495000; 2498079; 2516729; 2833519; 3111527; 3131773; 6304075; 6743699; 7566346; 7566652; 7567473; 7684835; 7706316; 7931292; 7936241; 7972031; 8522593; 8546229; 8620924; 8631898; 8632146; 8642405; 8910513; 8999860; 9147408; 9199504; 9326300; 9353289; 9512010; 9546672; 9565682; 9614189; 9629852; 9636220; 9641683; 9689133; 9735171; 9736630; 9736786; 9763511; 9771888; 9789048; 9832145; 9836646; 9922135; 9973279; 10090741; 10208578; 10214944; 10374757; 10391244; 10393977; 10412802; 10464279; 10489057; 10514099; 10534245; 10604746; 10737616; 10747907; 10762698; 10767321; 10802785; 10822460; 10840038; 10899436; 10899937; 10987820; 11071507; 11089577; 11104762; 11117541; 11117542; 11117553; 11162250; 11166961; 11181841; 11220749; 11255441; 11264299; 11278002; 11303757; 11311121; 11313338; 11391737; 11456301; 11585254; 11601501; 11641718; 11698154; 11698390; 11706972; 11812770; 11826099; 11831025; 11831556; 11837744; 11852060; 11861703; 11889249; 11891833; 11906000; 11912108; 11921059; 11939896; 11958849; 11959122; 11959919; 11971081; 11971082; 11988340; 12000767; 12032355; 12056929; 12070658; 12082079; 12112079; 12144513; 12176984; 12177374; 12198126; 12212558; 12220379; 12226093; 12231446; 12325083; 12368187; 12368474; 12387894; 12387897; 12435421; 12464279; 12470988; 12473774; 12476321; 12477932; 12492138; 12505985; 12509859; 12527113; 12565146; 12573250; 12590615; 12629248; 12641733; 12649279; 12678504; 12710929; 12714745; 12756133; 12765608; 12796837; 12811584; 12826737; 12847166; 12853572; 12872001; 12883828; 12888622; 12911634; 12925374; 12932819; 12937143; 12963086; 12975285; 14503643; 14517953; 14523627; 14572459; 14594945; 14595660; 14600827; 14612456; 14615799; 14627651; 14636947; 14660557; 14697667; 14702039; 14730711; 14761950; 14769047; 14769048; 14962978; 14963027; 14966169; 14967043; 14991810; 14991828; 14991829; 14993287; 14993907; 14999081; 15004327; 15009664; 15020716; 15034924; 15053964; 15075227; 15083285; 15096589; 15106853; 15115761; 15121898; 15126504; 15140937; 15178931; 15178932; 15178951; 15198676; 15201350; 15228591; 15228592; 15240881; 15249677; 15266787; 15283964; 15293277; 15297935; 15302935; 15345747; 15356202; 15365985; 15372253; 15376481; 15385569; 15447663; 15459824; 15464261; 15475684; 15477533; 15489334; 15509534; 15525651; 15532542; 15542598; 15546861; 15570502; 15596612; 15627775; 15638805; 15652510; 15671021; 15721985; 15732111; 15733856; 15746184; 15750210; 15765246; 15792962; 15795929; 15822905; 15823045; 15823754; 15848182; 15855160; 15855649; 15869817; 15878580; 15882073; 15904919; 15940384; 15950767; 15953362; 15963640; 15963990; 15973541; 15975068; 15994305; 15997419; 16000144; 16005901; 16014719; 16020737; 16023860; 16042549; 16114883; 16115884; 16125396; 16129700; 16143467; 16157753; 16165272; 16176937; 16182262; 16195395; 16221853; 16225961; 16226718; 16226838; 16240366; 16246844; 16251138; 16275660; 16315267; 16362633; 16362832; 16364302; 16365047; 16371011; 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18662339; 18668363; 18671940; 18679696; 18702695; 18725924; 18765933; 18768919; 18771816; 18785640; 18803399; 18803648; 18803694; 18805362; 18806919; 18830724; 18841019; 18843496; 18848323; 18854867; 18925637; 18930114; 18930955; 18940799; 18946722; 18948254; 18971445; 18985386; 18991351; 18992292; 18992725; 19001166; 19010781; 19011737; 19022385; 19039589; 19057915; 19070646; 19074461; 19090983; 19091059; 19112391; 19126401; 19153649; 19155101; 19157893; 19158426; 19165922; 19190923; 19221889; 19224617; 19226187; 19232747; 19236926; 19240967; 19255408; 19264130; 19273536; 19304664; 19307538; 19308965; 19324008; 19356824; 19365643; 19371722; 19401603; 19429119; 19433664; 19450558; 19450659; 19478088; 19491104; 19498037; 19517062; 19523877; 19524111; 19525898; 19527721; 19540327; 19542604; 19542619; 19549281; 19558713; 19559700; 19560101; 19573950; 19591849; 19625749; 19647741; 19654187; 19665462; 19667268; 19681044; 19684401; 19686388; 19691919; 19693433; 19695742; 19700222; 19730170; 19730171; 19736351; 19749420; 19766248; 19768372; 19770469; 19775775; 19782075; 19786698; 19794916; 19812213; 19826005; 19858456; 19879020; 19889475; 19895707; 19897570; 19912324; 19914360; 19915575; 19919107; 19923278; 19926863; 19936237; 19938685; 19940479; 19943189; 19959468; 19961883; 20004218; 20005921; 20020531; 20045477; 20061629; 20070850; 20085902; 20097445; 20133017; 20133804; 20143409; 20157246; 20159774; 20171924; 20193038; 20219685; 20236174; 20301387; 20301402; 20301678; 20357768; 20359515; 20375017; 20377816; 20379729; 20415586; 20437541; 20460118; 20466727; 20466736; 20471030; 20473135; 20473510; 20478262; 20498436; 20513372; 20520830; 20538372; 20538373; 20544828; 20549384; 20553310; 20561037; 20571215; 20574532; 20579400; 20599474; 20599975; 20606400; 20615469; 20620663; 20650958; 20658984; 20658986; 20658988; 20658994; 20658995; 20658996; 20660113; 20663882; 20665688; 20678071; 20678073; 20678074; 20679343; 20683187; 20708332; 20711061; 20711177; 20720012; 20800603; 20805224; 20805522; 20837015; 20837363; 20838030; 20838929; 20847421; 20862329; 20869593; 20876472; 20881758; 20921222; 20921227; 20926667; 20927324; 20927385; 20930301; 20951764; 20974297; 21044948; 21044986; 21054681; 21058943; 21061060; 21062361; 21062741; 21062914; 21063069; 21073671; 21081103; 21085657; 21098287; 21098973; 21123557; 21127069; 21131359; 21135556; 21157033; 21157379; 21159074; 21176711; 21181298; 21210655; 21212533; 21243369; 21276080; 21281813; 21288907; 21292315; 21320871; 21321341; 21325519; 21327254; 21333649; 21339331; 21340680; 21342021; 21342022; 21343338; 21343707; 21344240; 21348938; 21367856; 21367866; 21368381; 21388338; 21391235; 21397051; 21403021; 21425343; 21435449; 21439371; 21442128; 21450369; 21450370; 21482827; 21489655; 21489990; 21492964; 21498513; 21504113; 21504133; 21510936; 21530001; 21550980; 21555518; 21555603; 21558644; 21568901; 21575385; 21577325; 21604267; 21613474; 21613482; 21638028; 21666499; 21670401; 21677375; 21685912; 21692989; 21694458; 21698260; 21705366; 21714002; 21738487; 21753165; 21753175; 21755018; 21763357; 21763469; 21807765; 21811019; 21816655; 21822709; 21825215; 21839061; 21841250; 21841253; 21846727; 21849646; 21854751; 21860086; 21860087; 21881826; 21888627; 21898123; 21907761; 21910444; 21911695; 21919991; 21931162; 21934536; 21934724; 21942206; 21943955; 21945393; 21949350; 21966400; 21969238; 21976528; 21978388; 21980472; 21983102; 21985244; 22002427; 22002658; 22022446; 22027014; 22039514; 22039833; 22057275; 22085312; 22102449; 22104010; 22109955; 22116524; 22127750; 22159117; 22170881; 22174735; 22176350; 22177996; 22193445; 22213792; 22214313; 22221882; 22229117; 22232001; 22233767; 22235112; 22236337; 22269004; 22272245; 22291015; 22291217; 22294156; 22303461; 22304362; 22310385; 22312444; 22337826; 22343013; 22344634; 22359235; 22366795; 22366796; 22367970; 22396417; 22401494; 22403409; 22406198; 22419736; 22460328; 22461630; 22464332; 22490326; 22492994; 22496370; 22504418; 22504419; 22504420; 22521809; 22530600; 22532069; 22535953; 22539343; 22556362; 22561167; 22565157; 22595371; 22595621; 22613722; 22615831; 22637478; 22648764; 22659094; 22668776; 22677170; 22699846; 22701727; 22723018; 22764226; 22767602; 22797329; 22802095; 22819391; 22833681; 22862303; 22862741; 22867711; 22910909; 22911817; 22927204; 22936006; 22940644; 22941973; 22952452; 22965877; 22975846; 22976542; 22984603; 23001634; 23012332; 23019339; 23028730; 23034520; 23036273; 23041958; 23043292; 23047372; 23053136; 23064258; 23085090; 23087208; 23105105; 23114515; 23129775; 23154429; 23157676; 23160422; 23225000; 23234879; 23237806; 23247080; 23254634; 23264626; 23269837; 23271055; 23276384; 23317568; 23332171; 23332172; 23338682; 23340677; 23362255; 23396350; 23418567; 23423488; 23443659; 23446558; 23458258; 23475578; 23475817; 23479202; 23487739; 23499461; 23507417; 23515417; 23528367; 23554879; 23576620; 23583980; 23585562; 23585566; 23621301; 23624859; 23631819; 23640887; 23659998; 23664753; 23666174; 23684085; 23715095; 23717682; 23721814; 23789343; 23798682; 23824268; 23827424; 23900411; 23943618; 23999428; 24063855; 24072703; 24081456; 24089520; 24163366; 24212387; 24225352; 24250222; 24251416; 24256615 microtubule-associated protein tau Ensembl:ENSG00000186868 HGNC:6893 HPRD:01142 MIM:157140 Vega:OTTHUMG00000168833 MAPT Bin Zhao, Yue Liu, Oliver He MAT MATA1 SAMS SAMS1 WEB: http://www.ncbi.nlm.nih.gov/gene MAT1A methionine adenosyltransferase I, alpha 4143 RP11-36D19.2 10q22 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0000096 (EC: TAS); GO_0004478 (EC: IEA); GO_0005524 (EC: IEA); GO_0005829 (EC: TAS); GO_0006520 (EC: TAS, PMID: 1772450); GO_0006556 (EC: IEA); GO_0006730 (EC: IEA); GO_0006805 (EC: TAS); GO_0032259 (EC: TAS); GO_0034641 (EC: TAS); GO_0044281 (EC: TAS); GO_0046872 (EC: IEA) PMID: 1056281; 1683972; 1772450; 3812486; 7213623; 7271238; 7560086; 8314764; 8393662; 8770875; 9042912; 9175157; 9482646; 10677294; 12477932; 15164054; 15489334; 15935930; 16341674; 16385451; 18500573; 19048631; 19161160; 19913121; 20146079; 20201926; 20335551; 20628086; 20634891; 20675163; 21185701; 21678410; 21813468; 21890473; 21906983; 22270009; 22318685; 22807109; 22939629; 22951388; 23000965; 23241961; 23425511 methionine adenosyltransferase I, alpha Ensembl:ENSG00000151224 HGNC:6903 HPRD:02013 MIM:610550 Vega:OTTHUMG00000018613 MAT1A Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene MBP myelin basic protein 4155 18q23 20140408 9606 18 protein-coding Official from a nomenclature committee GO_0002020 (EC: IEA); GO_0005515 (EC: IPI, PMID: 17064692); GO_0005634 (EC: IEA); GO_0005886 (EC: IEA); GO_0006955 (EC: TAS, PMID: 7504278); GO_0007268 (EC: TAS, PMID: 2434243); GO_0007417 (EC: TAS, PMID: 2434243); GO_0008366 (EC: TAS, PMID: 2434243); GO_0009636 (EC: IEA); GO_0019911 (EC: IEA); GO_0021762 (EC: IEP); GO_0033269 (EC: IEA); GO_0042552 (EC: IEA); GO_0043025 (EC: IEA); GO_0043218 (EC: IEA); GO_0050771 (EC: IEA); GO_0061024 (EC: IEA) PMID: 1689270; 2413024; 2414074; 2425357; 2426402; 2427738; 2434243; 2437795; 2442403; 2449425; 2466844; 2467009; 2472816; 4099924; 4108501; 4924231; 5128665; 6083474; 6201481; 7504278; 7544282; 7574672; 7665586; 7685161; 8170997; 8375396; 8537403; 8544862; 8647104; 8786845; 8798720; 8846788; 8889548; 9020143; 9136767; 9155018; 9207191; 9628874; 9782128; 9792705; 9873047; 10339476; 10346818; 10371216; 10383403; 10390541; 10523312; 10708586; 10910078; 10947953; 10958680; 10980603; 11080454; 11120354; 11124993; 11152681; 11258664; 11295122; 11402450; 11500515; 11570821; 11641781; 11683387; 11864968; 11875070; 11940329; 11964256; 12101123; 12237860; 12377379; 12429732; 12477932; 12618862; 12760422; 12939427; 12955071; 12965257; 14530346; 14579272; 14594813; 14702039; 14702098; 14714495; 14743429; 15009677; 15147269; 15328539; 15380617; 15489334; 15728454; 15791647; 15797222; 15870294; 15927069; 16079912; 16216881; 16269541; 16387849; 16412431; 16441258; 16712791; 16713569; 16842822; 16871440; 16900754; 17064692; 17081983; 17259179; 17260967; 17331951; 17351112; 17415991; 17584768; 17599067; 17622942; 17690840; 17706965; 17823288; 17906618; 18067995; 18284662; 18543229; 18663124; 18713991; 18720029; 18802067; 19014520; 19034380; 19053745; 19110265; 19154657; 19293155; 19372141; 19385666; 19423540; 19468823; 19570024; 19663312; 19690890; 19692707; 19826009; 19910486; 19950581; 20212043; 20406964; 20438785; 20471030; 20629634; 20807757; 21203542; 21312222; 21315177; 21551065; 21601398; 21609718; 21673997; 21806997; 21860087; 21898163; 22258479; 22496821; 22538354; 22542401; 22705344; 22888134; 22890910; 22939629; 22968126; 23166209; 23264040; 23315809; 23510371; 23520443; 23524951; 23726766 myelin basic protein MBP Bin Zhao, Yue Liu, Oliver He C5DELq14.3 DEL5q14.3 WEB: http://www.ncbi.nlm.nih.gov/gene MEF2C myocyte enhancer factor 2C 4208 5q14.3 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0000122 (EC: IMP, PMID: 18079734); GO_0000165 (EC: IDA, PMID: 9858528); GO_0000165 (EC: IMP, PMID: 11160896); GO_0000977 (EC: IDA, PMID: 8455629); GO_0000981 (EC: ISS); GO_0000983 (EC: IDA, PMID: 8455629); GO_0000987 (EC: IEA); GO_0001046 (EC: IEA); GO_0001077 (EC: IDA, PMID: 15486975); GO_0001568 (EC: ISS); GO_0001649 (EC: ISS); GO_0001782 (EC: ISS); GO_0001947 (EC: ISS); GO_0001958 (EC: ISS); GO_0001974 (EC: ISS); GO_0002062 (EC: ISS); GO_0002224 (EC: TAS); GO_0002467 (EC: ISS); GO_0002634 (EC: ISS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0003138 (EC: ISS); GO_0003139 (EC: ISS); GO_0003151 (EC: ISS); GO_0003185 (EC: ISS); GO_0003211 (EC: ISS); GO_0003677 (EC: IDA, PMID: 11744164); GO_0003680 (EC: IDA, PMID: 15486975); GO_0003682 (EC: IEA); GO_0003700 (EC: IDA, PMID: 16043483); GO_0003705 (EC: IEA); GO_0005515 (EC: IPI, PMID: 15486975); GO_0005634 (EC: IDA, PMID: 11744164); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA, PMID: 8455629); GO_0006915 (EC: IEA); GO_0006959 (EC: ISS); GO_0007399 (EC: TAS, PMID: 8455629); GO_0007507 (EC: IEP, PMID: 10458488); GO_0007507 (EC: ISS); GO_0007507 (EC: NAS, PMID: 15486975); GO_0007517 (EC: TAS, PMID: 8455629); GO_0007519 (EC: ISS); GO_0007521 (EC: ISS); GO_0007611 (EC: ISS); GO_0009615 (EC: IEP); GO_0010613 (EC: IEA); GO_0010628 (EC: IDA); GO_0010629 (EC: ISS); GO_0010694 (EC: ISS); GO_0014033 (EC: ISS); GO_0014898 (EC: IEA); GO_0014902 (EC: IEP, PMID: 8455629); GO_0016607 (EC: IDA, PMID: 18079734); GO_0021542 (EC: IEA); GO_0030017 (EC: IEA); GO_0030182 (EC: IEP, PMID: 8455629); GO_0030182 (EC: ISS); GO_0030220 (EC: ISS); GO_0030224 (EC: IEA); GO_0030279 (EC: IDA, PMID: 17696759); GO_0030318 (EC: ISS); GO_0030501 (EC: ISS); GO_0030890 (EC: ISS); GO_0033197 (EC: IEA); GO_0033613 (EC: IPI, PMID: 11160896); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035198 (EC: IDA); GO_0035666 (EC: TAS); GO_0035690 (EC: ISS); GO_0035984 (EC: ISS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042100 (EC: ISS); GO_0042692 (EC: TAS); GO_0042826 (EC: IEA); GO_0043234 (EC: IDA, PMID: 15486975); GO_0043524 (EC: ISS); GO_0044212 (EC: ISS); GO_0045087 (EC: TAS); GO_0045652 (EC: ISS); GO_0045663 (EC: IMP, PMID: 9770491); GO_0045666 (EC: ISS); GO_0045669 (EC: ISS); GO_0045893 (EC: IDA, PMID: 11744164); GO_0045944 (EC: IDA, PMID: 15486975); GO_0045944 (EC: IMP, PMID: 11160896); GO_0046982 (EC: IPI, PMID: 9858528); GO_0048011 (EC: TAS); GO_0048643 (EC: IMP, PMID: 9770491); GO_0048666 (EC: ISS); GO_0048703 (EC: IEA); GO_0050680 (EC: IEA); GO_0050853 (EC: ISS); GO_0051145 (EC: ISS); GO_0051149 (EC: TAS); GO_0051403 (EC: TAS); GO_0055012 (EC: ISS); GO_0060021 (EC: IEA); GO_0060025 (EC: ISS); GO_0060045 (EC: ISS); GO_0060297 (EC: IEA); GO_0060536 (EC: IEA); GO_0061333 (EC: ISS); GO_0071222 (EC: ISS); GO_0071277 (EC: ISS); GO_0071300 (EC: IEA); GO_0071333 (EC: IEA); GO_0071374 (EC: IDA, PMID: 17696759); GO_0071498 (EC: ISS); GO_0071560 (EC: IDA, PMID: 9770491); GO_0071837 (EC: IEA); GO_0071864 (EC: IEA); GO_0072102 (EC: ISS); GO_0072160 (EC: ISS); GO_0090073 (EC: ISS); GO_2000111 (EC: ISS); GO_2000727 (EC: IDA, PMID: 9857019); GO_2000987 (EC: ISS); GO_2001013 (EC: ISS); GO_2001016 (EC: IDA) PMID: 7679508; 8455629; 8548800; 8575763; 8575784; 8663403; 8900141; 8948587; 9001254; 9069290; 9384584; 9418854; 9748305; 9753748; 9770491; 9798649; 9857019; 9858528; 10082551; 10330143; 10458488; 10523670; 10737771; 10790371; 10805738; 11160896; 11279209; 11486037; 11504882; 11535832; 11554755; 11744164; 11792813; 11809751; 12061776; 12130539; 12135755; 12376544; 12477932; 12659851; 12709441; 12861002; 15084602; 15140898; 15276183; 15340086; 15342556; 15486975; 15561718; 15743821; 15743823; 15831463; 15834131; 15923648; 15964851; 16043483; 16469744; 16478538; 16504037; 16510869; 17611778; 17696759; 17903302; 18029348; 18067759; 18079734; 18332106; 18463162; 18588859; 18660489; 18950845; 19011954; 19065516; 19093215; 19453261; 19553684; 19592390; 19720801; 19751190; 19801982; 19828686; 19913121; 20211142; 20333642; 20412115; 20513142; 20610535; 20628086; 20709755; 20881960; 20936779; 21060863; 21481790; 21533022; 21652706; 21849497; 21890473; 21901155; 21906983; 21988832; 22073279; 22139419; 22275376; 22363514; 22449245; 22504420; 22670137; 22718505; 22798246; 22997707; 23001426; 23174904; 23226416; 23382706; 23389741; 23400010; 23402836; 23468913; 23572186; 23776548; 24008018; 24290359 myocyte enhancer factor 2C Ensembl:ENSG00000081189 HGNC:6996 HPRD:02809 MIM:600662 Vega:OTTHUMG00000162634 MEF2C Bin Zhao, Yue Liu, Oliver He GIF GLIF MMIF WEB: http://www.ncbi.nlm.nih.gov/gene MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 4282 22q11.23 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0001516 (EC: IDA, PMID: 12782713); GO_0002906 (EC: IEA); GO_0004167 (EC: IDA, PMID: 17526494); GO_0005102 (EC: IPI, PMID: 12782713); GO_0005125 (EC: IDA, PMID: 12782713); GO_0005126 (EC: IPI, PMID: 17045821); GO_0005515 (EC: IPI, PMID: 12681488); GO_0005576 (EC: IDA, PMID: 12782713); GO_0005615 (EC: IEA); GO_0005737 (EC: IEA); GO_0006954 (EC: IEA); GO_0007166 (EC: IDA, PMID: 12782713); GO_0007569 (EC: IEA); GO_0008283 (EC: IDA, PMID: 12782713); GO_0009986 (EC: IDA, PMID: 12782713); GO_0010629 (EC: IDA, PMID: 10562313); GO_0010739 (EC: IDA, PMID: 17045821); GO_0019752 (EC: IDA, PMID: 12782713); GO_0030330 (EC: IEA); GO_0030890 (EC: IDA, PMID: 12782713); GO_0031666 (EC: IEA); GO_0032269 (EC: IEA); GO_0033033 (EC: IEA); GO_0033138 (EC: IDA, PMID: 17045821); GO_0042056 (EC: IDA, PMID: 19602265); GO_0042327 (EC: IDA, PMID: 12782713); GO_0043030 (EC: NAS, PMID: 12782713); GO_0043066 (EC: IDA, PMID: 12782713); GO_0043406 (EC: IEA); GO_0043518 (EC: IDA, PMID: 17045821); GO_0045087 (EC: IEA); GO_0048146 (EC: IDA, PMID: 12782713); GO_0050178 (EC: IDA, PMID: 16285950); GO_0050715 (EC: IDA, PMID: 19602265); GO_0050731 (EC: IDA, PMID: 17045821); GO_0050918 (EC: IDA, PMID: 19602265); GO_0061078 (EC: IEA); GO_0061081 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070207 (EC: IPI, PMID: 17526494); GO_0070374 (EC: IDA, PMID: 12782713); GO_0071157 (EC: IDA, PMID: 10562313); GO_0090238 (EC: IEA); GO_0090344 (EC: IDA, PMID: 10562313); GO_1902166 (EC: IDA, PMID: 17045821); GO_2000343 (EC: IEA) PMID: 1286669; 2552447; 3917866; 7558020; 7679497; 7683862; 7947826; 8188240; 8234256; 8289313; 8601455; 8610159; 8643551; 8647256; 8766818; 8988336; 9002552; 9006339; 9027512; 10334104; 10353846; 10562313; 11089976; 11170644; 11259268; 11508429; 11875000; 11920501; 11978887; 11985788; 11997397; 12009356; 12032852; 12070782; 12109441; 12126556; 12180727; 12186913; 12218292; 12218308; 12235522; 12355488; 12402212; 12445161; 12477932; 12480958; 12507885; 12576459; 12607777; 12612911; 12615835; 12626594; 12631237; 12665801; 12667094; 12681488; 12738641; 12740374; 12746913; 12782713; 12796500; 12822893; 12847682; 12965208; 14502271; 14551601; 14581488; 14607690; 14736878; 14760795; 14962818; 15018649; 15065001; 15146413; 15146431; 15170913; 15216464; 15231747; 15286457; 15292349; 15304087; 15308783; 15461802; 15472203; 15489334; 15545061; 15545824; 15576462; 15585204; 15585220; 15592455; 15612021; 15630728; 15659324; 15757663; 15800984; 15815686; 15820792; 15838879; 15910495; 15910597; 16000172; 16051683; 16085663; 16115023; 16133063; 16169070; 16179637; 16189514; 16200611; 16205314; 16220288; 16224818; 16243796; 16247506; 16285950; 16314470; 16314559; 16317091; 16369812; 16385258; 16388506; 16488392; 16527487; 16538639; 16677407; 16709839; 16724072; 16767681; 16780713; 16807115; 16820919; 16839849; 16854377; 16861224; 16872482; 16893895; 16929348; 17005573; 17029206; 17045821; 17075815; 17108334; 17142775; 17166737; 17172590; 17181929; 17206642; 17215861; 17224449; 17353931; 17435771; 17438452; 17438455; 17495357; 17526494; 17541237; 17559578; 17591062; 17592555; 17620429; 17658526; 17706208; 17709373; 17712545; 17728788; 17763209; 17786285; 17854804; 17854909; 17869648; 17906677; 17912466; 18034423; 18037272; 18054247; 18060744; 18074864; 18078632; 18081874; 18097599; 18165264; 18171527; 18171602; 18177450; 18228042; 18235500; 18239193; 18242614; 18261992; 18270460; 18356846; 18362243; 18426738; 18466513; 18469521; 18474653; 18490733; 18493321; 18502749; 18618071; 18676531; 18677096; 18680514; 18684922; 18710704; 18720262; 18795803; 18815136; 18832726; 18842989; 18852457; 18853133; 18930766; 19009023; 19038405; 19056867; 19062717; 19081768; 19109179; 19155217; 19157791; 19167373; 19170716; 19188484; 19196797; 19260777; 19299454; 19317738; 19346297; 19376177; 19394321; 19406662; 19417556; 19423540; 19428548; 19454686; 19464392; 19475570; 19591577; 19601712; 19602265; 19644855; 19665027; 19720544; 19723024; 19724898; 19726058; 19737008; 19738201; 19747950; 19759012; 19762145; 19773451; 19776019; 19776337; 19799813; 19829123; 19913121; 19938192; 19941661; 19950249; 20038293; 20085845; 20127054; 20149326; 20178462; 20193596; 20200619; 20203087; 20233515; 20237496; 20303284; 20346241; 20369477; 20380014; 20382217; 20383199; 20406964; 20438785; 20439102; 20447688; 20448056; 20452482; 20460119; 20467327; 20471506; 20499270; 20534506; 20546256; 20573157; 20598902; 20621719; 20628086; 20646540; 20673868; 20805296; 20807568; 20811626; 20829434; 20847814; 20861157; 20863520; 20872800; 20878093; 20944103; 20980171; 21030269; 21045753; 21071513; 21087445; 21106938; 21139048; 21162929; 21169549; 21208809; 21209875; 21269946; 21281800; 21283538; 21283592; 21319273; 21360573; 21401926; 21417823; 21512965; 21515791; 21553324; 21575460; 21607559; 21607712; 21623990; 21641401; 21684012; 21725855; 21750916; 21773885; 21792010; 21817065; 21823060; 21848392; 21852299; 21875883; 21890178; 21890473; 21906983; 21942715; 21963094; 21988832; 21990375; 22001757; 22007254; 22053931; 22079264; 22099602; 22127710; 22166284; 22174124; 22206839; 22271573; 22302395; 22327470; 22415145; 22430150; 22449335; 22451332; 22461895; 22505724; 22543583; 22609310; 22611320; 22623428; 22649515; 22676646; 22693633; 22742858; 22759564; 22782901; 22810585; 22813781; 22820623; 22883521; 22892326; 22893706; 22898393; 22909194; 22927777; 22939113; 22939629; 22949182; 22952837; 22988252; 23000965; 23023114; 23028743; 23043599; 23050964; 23060578; 23064787; 23068083; 23125447; 23179933; 23207293; 23246423; 23272137; 23354841; 23383040; 23402792; 23403077; 23410506; 23411097; 23451183; 23497377; 23523092; 23526214; 23537651; 23552723; 23707797; 23770720; 23776208; 23794947; 23882081; 24003215; 24039418; 24151396; 24194192; 24273891 macrophage migration inhibitory factor (glycosylation-inhibiting factor) HGNC:7097 HPRD:01091 MIM:153620 MIF Bin Zhao, Yue Liu, Oliver He CALLA CD10 NEP SFE WEB: http://www.ncbi.nlm.nih.gov/gene MME membrane metallo-endopeptidase 4311 3q25.2 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0001822 (EC: IEP); GO_0002003 (EC: TAS); GO_0004175 (EC: IDA, PMID: 15283675); GO_0004175 (EC: IMP, PMID: 2531377); GO_0004222 (EC: IMP, PMID: 2521388); GO_0005515 (EC: IPI, PMID: 17342744); GO_0005737 (EC: IDA); GO_0005886 (EC: IDA); GO_0005886 (EC: TAS); GO_0005887 (EC: NAS, PMID: 2521388); GO_0005903 (EC: IDA); GO_0006508 (EC: IDA); GO_0006518 (EC: ISS); GO_0008021 (EC: ISS); GO_0008270 (EC: IDA, PMID: 8168535); GO_0016021 (EC: NAS, PMID: 2968607); GO_0019233 (EC: ISS); GO_0030424 (EC: ISS); GO_0030425 (EC: ISS); GO_0042277 (EC: ISS); GO_0044267 (EC: TAS); GO_0044306 (EC: ISS); GO_0045202 (EC: ISS); GO_0046449 (EC: IMP); GO_0050435 (EC: ISS); GO_0070062 (EC: IDA, PMID: 19056867); GO_0071345 (EC: IDA); GO_0071492 (EC: IDA); GO_0071493 (EC: IDA); GO_0090399 (EC: IEP) PMID: 1660144; 2201681; 2417254; 2521237; 2521388; 2528730; 2531377; 2612455; 2736261; 2968607; 2971756; 2972276; 2984462; 2994530; 3157879; 3162217; 7532408; 8003005; 8168535; 8631021; 8687431; 8943850; 9232196; 9247159; 9313778; 9659899; 9857225; 10669592; 11104793; 11140838; 11170145; 11367540; 11849775; 11906289; 12070597; 12087466; 12102663; 12105192; 12140380; 12150966; 12203213; 12387451; 12393702; 12447961; 12477932; 12485446; 12527400; 12529960; 12657655; 12754344; 12754519; 12785004; 14550292; 14673956; 14739539; 14747736; 14749444; 14767532; 14968440; 15047060; 15100223; 15205682; 15217945; 15283675; 15286660; 15294904; 15464186; 15469471; 15489334; 15502805; 15548496; 15578072; 15668537; 15720419; 15785408; 15860464; 15870909; 15945081; 16123216; 16226260; 16344560; 16400325; 16652149; 16700740; 16722930; 16857799; 16877296; 16900210; 16900384; 16940054; 16943769; 16948517; 16984256; 17101991; 17207277; 17220478; 17294442; 17296585; 17335564; 17342744; 17363457; 17591969; 17662271; 17712175; 17845760; 17876294; 17885484; 17906676; 17928142; 17953966; 18042078; 18092952; 18182043; 18292286; 18370954; 18393807; 18518902; 18539150; 18545147; 18602473; 18605079; 18619643; 18806483; 19019493; 19047112; 19056867; 19057576; 19127446; 19152193; 19196432; 19250583; 19287335; 19288202; 19326964; 19437324; 19448593; 19515046; 19575892; 19606063; 19656156; 19661328; 19752720; 19787248; 19816087; 19817893; 19864659; 19897485; 19925052; 19948975; 19961253; 20014550; 20051779; 20051780; 20061637; 20079015; 20105452; 20175824; 20184665; 20204382; 20376800; 20390424; 20459800; 20468064; 20506111; 20546336; 20574156; 20663017; 20685603; 20711432; 20716621; 20856894; 20858953; 20886092; 20947507; 20957047; 21052031; 21076839; 21225496; 21315759; 21365649; 21425402; 21499231; 21515054; 21585282; 21609487; 21651905; 21666788; 21677537; 21681600; 21775056; 21804528; 21835428; 21877416; 21883368; 21963094; 21988858; 21989348; 22006372; 22014058; 22183801; 22257901; 22261707; 22272689; 22286396; 22300665; 22371247; 22384224; 22410801; 22417750; 22464152; 22492182; 22572771; 22767595; 22880404; 22898766; 22994707; 23063927; 23065018; 23138928; 23219141; 23339695; 23348903; 23356903; 23509938; 23566254; 23752268; 23838604 membrane metallo-endopeptidase Ensembl:ENSG00000196549 HGNC:7154 HPRD:00392 MIM:120520 Vega:OTTHUMG00000158455 MME Bin Zhao, Yue Liu, Oliver He CLG4 CLG4A MMP-II MONA TBE-1 WEB: http://www.ncbi.nlm.nih.gov/gene MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 4313 16q13-q21 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0001525 (EC: IEA); GO_0001666 (EC: IEA); GO_0001955 (EC: IEA); GO_0001957 (EC: IEA); GO_0004222 (EC: IEA); GO_0004252 (EC: TAS); GO_0005515 (EC: IPI); GO_0005576 (EC: TAS); GO_0005578 (EC: IEA); GO_0005615 (EC: IDA, PMID: 18492766); GO_0005634 (EC: IEA); GO_0005739 (EC: IEA); GO_0005886 (EC: IEA); GO_0006508 (EC: TAS, PMID: 2834383); GO_0007566 (EC: IEA); GO_0008270 (EC: IEA); GO_0022617 (EC: TAS); GO_0030017 (EC: IEA); GO_0030198 (EC: TAS); GO_0030574 (EC: TAS); GO_0044267 (EC: TAS); GO_0060325 (EC: IEA); GO_0060346 (EC: IEA); GO_0071230 (EC: IEA) PMID: 1460022; 1846313; 1851724; 2071140; 2158484; 2162831; 2834383; 7523391; 7583664; 7683678; 7694569; 7782289; 7935812; 7947821; 7998967; 8549817; 8663297; 8663332; 8692946; 8862926; 9119036; 9148753; 9182583; 9343394; 9344465; 9438380; 9640131; 9699154; 9737711; 9853262; 9933646; 10196161; 10356396; 10419448; 10551873; 10652000; 10652271; 10900205; 10947989; 10986281; 10991943; 11114309; 11134507; 11168762; 11179305; 11220743; 11368514; 11382769; 11420387; 11431697; 11485914; 11571304; 11598182; 11728453; 11748988; 11756567; 11762702; 11782389; 11790786; 11792711; 11824472; 11833938; 11839588; 11844598; 11854622; 11889208; 11895494; 11918086; 11920503; 11928808; 11928813; 11929863; 11935310; 11948127; 11956628; 11961384; 12007723; 12023034; 12029498; 12032297; 12034345; 12039803; 12077518; 12085233; 12087091; 12103254; 12115722; 12122099; 12147229; 12147339; 12149192; 12193399; 12194986; 12198653; 12225805; 12235151; 12371906; 12372458; 12374789; 12376362; 12393408; 12393872; 12431239; 12438229; 12439941; 12451991; 12470034; 12471459; 12473650; 12475252; 12477932; 12479097; 12486137; 12522578; 12559990; 12569569; 12586836; 12587534; 12589095; 12601782; 12602913; 12614934; 12615834; 12632066; 12632084; 12642591; 12651627; 12657623; 12676736; 12684625; 12753080; 12764090; 12810672; 12832446; 12845641; 12861074; 12873995; 12878157; 12879005; 12880418; 12914776; 12939660; 12952836; 12967855; 12970394; 12970724; 14500349; 14519487; 14520690; 14580155; 14583471; 14604886; 14614057; 14644155; 14644777; 14661256; 14666611; 14679018; 14694003; 14697951; 14710472; 14713104; 14732714; 14744781; 14766248; 14871985; 14973177; 14981939; 14982725; 14983226; 14990702; 14990972; 14996438; 15004438; 15009703; 15015767; 15051038; 15056834; 15067014; 15102849; 15146192; 15165255; 15201662; 15241180; 15248212; 15248826; 15250832; 15254682; 15255544; 15265790; 15271946; 15277330; 15280384; 15280448; 15317806; 15317818; 15351863; 15375490; 15381707; 15449075; 15475447; 15485653; 15489233; 15489334; 15492291; 15522165; 15541021; 15557756; 15567754; 15569994; 15604254; 15609121; 15609318; 15609323; 15616792; 15621117; 15632190; 15637056; 15651999; 15665288; 15665394; 15672417; 15691365; 15731163; 15743799; 15754118; 15756447; 15820246; 15831360; 15841469; 15866216; 15878967; 15885317; 15904490; 15911696; 15929171; 15944607; 15949313; 15955221; 15955448; 15955449; 15983226; 15998676; 15998788; 16005367; 16018746; 16023005; 16023011; 16042227; 16082623; 16083752; 16097959; 16134528; 16142392; 16142692; 16146757; 16158251; 16168111; 16188099; 16188574; 16213873; 16260653; 16275157; 16306050; 16308106; 16313894; 16338908; 16339461; 16341461; 16344560; 16356191; 16359987; 16361361; 16364202; 16379022; 16407830; 16413616; 16414983; 16424893; 16425263; 16438723; 16453304; 16456793; 16458924; 16476613; 16510149; 16551362; 16575904; 16585124; 16615109; 16647062; 16718267; 16718824; 16722933; 16728425; 16739355; 16755991; 16772717; 16776850; 16778129; 16803520; 16829143; 16840178; 16884384; 16888681; 16891619; 16894529; 16897078; 16919028; 16940985; 16961137; 16967187; 16987162; 17000679; 17008230; 17012225; 17029196; 17033924; 17065436; 17067460; 17070879; 17071711; 17081126; 17088079; 17088321; 17089188; 17099140; 17109104; 17151781; 17175151; 17177839; 17178858; 17181997; 17182940; 17188706; 17189319; 17203213; 17203468; 17205957; 17208328; 17217338; 17226791; 17236757; 17237723; 17243139; 17258390; 17265493; 17289174; 17299802; 17299841; 17314270; 17320450; 17326127; 17335808; 17350093; 17357514; 17363400; 17364896; 17367869; 17374529; 17377415; 17383306; 17384031; 17409012; 17429393; 17435175; 17437609; 17448043; 17473191; 17486447; 17487426; 17488654; 17493172; 17493602; 17516913; 17540340; 17541305; 17545513; 17546628; 17559909; 17563705; 17564313; 17570740; 17589947; 17593815; 17607721; 17611666; 17613170; 17616173; 17623663; 17624083; 17624726; 17638886; 17640671; 17650671; 17653824; 17660250; 17661346; 17666398; 17671679; 17678975; 17680282; 17699594; 17706116; 17706812; 17718386; 17725804; 17786346; 17845054; 17851253; 17876296; 17879021; 17886098; 17893005; 17893430; 17901377; 17908800; 17923814; 17943549; 17949555; 17950725; 17958893; 17962725; 17972522; 17981679; 17986062; 18000234; 18025061; 18029348; 18031543; 18035073; 18035727; 18038907; 18042068; 18045645; 18049448; 18052707; 18062285; 18063683; 18069632; 18070420; 18081721; 18088350; 18091353; 18093986; 18155181; 18160708; 18166633; 18172354; 18177474; 18177649; 18182154; 18185989; 18187184; 18194849; 18205826; 18208802; 18210196; 18214299; 18217401; 18220784; 18236174; 18251742; 18253117; 18256065; 18265895; 18283635; 18288638; 18288718; 18291374; 18292822; 18292932; 18295959; 18298353; 18308831; 18314110; 18329693; 18330957; 18332090; 18332634; 18337444; 18340378; 18359774; 18366007; 18378414; 18398039; 18400453; 18424416; 18425389; 18426670; 18431027; 18438431; 18444803; 18455130; 18462748; 18468407; 18469019; 18472160; 18473733; 18477480; 18483282; 18492766; 18496568; 18498066; 18506186; 18543216; 18552985; 18560213; 18575776; 18579756; 18580857; 18593949; 18597705; 18611410; 18618693; 18627313; 18636124; 18641922; 18644390; 18644862; 18651826; 18652765; 18653973; 18663625; 18664479; 18665467; 18670324; 18683733; 18692810; 18701818; 18707587; 18711060; 18712166; 18713744; 18714566; 18757369; 18773430; 18782525; 18784838; 18802398; 18802702; 18805052; 18814268; 18818748; 18829111; 18829229; 18835646; 18852494; 18937938; 18940384; 18946196; 18950008; 18971037; 18971427; 18974156; 19007982; 19019335; 19020757; 19022775; 19088110; 19088827; 19094228; 19100442; 19101987; 19105397; 19109975; 19116140; 19117773; 19121849; 19122458; 19124506; 19132754; 19134348; 19141395; 19159011; 19165813; 19176371; 19188819; 19189315; 19191857; 19196101; 19199380; 19212830; 19221481; 19223381; 19236750; 19241124; 19243899; 19248107; 19249761; 19266599; 19274436; 19281093; 19286653; 19287959; 19288452; 19295411; 19303106; 19324884; 19330734; 19331801; 19332048; 19337556; 19338750; 19345347; 19358835; 19360430; 19386107; 19391484; 19395678; 19426551; 19438747; 19445018; 19448672; 19449375; 19454611; 19455469; 19459623; 19460733; 19464975; 19465902; 19466389; 19469865; 19477063; 19484988; 19507256; 19515587; 19523650; 19523958; 19525975; 19527514; 19528914; 19529860; 19546837; 19551542; 19551856; 19560452; 19562509; 19574670; 19575173; 19577357; 19578796; 19580633; 19581306; 19594729; 19610062; 19615732; 19617223; 19617714; 19625121; 19637058; 19643940; 19653001; 19671357; 19682073; 19687355; 19698156; 19700865; 19709349; 19716817; 19723042; 19723139; 19724860; 19724922; 19731823; 19760465; 19780834; 19786072; 19787626; 19789190; 19814619; 19816602; 19820359; 19821096; 19853299; 19861308; 19874467; 19875168; 19875755; 19885578; 19887570; 19889076; 19901964; 19903768; 19903858; 19913121; 19921476; 19930715; 19939245; 19954064; 19956847; 19995403; 19995435; 19997654; 20003765; 20021962; 20021964; 20031158; 20044778; 20064641; 20071690; 20082877; 20091096; 20100617; 20110530; 20113256; 20129576; 20133364; 20138860; 20140262; 20145123; 20160036; 20175118; 20195229; 20207476; 20211062; 20211065; 20216978; 20219012; 20222942; 20230421; 20233617; 20305284; 20333791; 20346360; 20353950; 20360147; 20364697; 20372784; 20375027; 20381119; 20382120; 20394501; 20404912; 20416077; 20432471; 20435584; 20450704; 20452482; 20453000; 20453486; 20455995; 20473759; 20482566; 20484597; 20485444; 20501419; 20501425; 20510080; 20514432; 20514437; 20514447; 20529817; 20541540; 20563853; 20565774; 20576603; 20586027; 20587546; 20590473; 20600798; 20616161; 20616708; 20625418; 20625691; 20628086; 20628624; 20634891; 20646497; 20646600; 20652762; 20654108; 20654122; 20672350; 20673868; 20685029; 20717917; 20724289; 20725135; 20730428; 20730561; 20808730; 20811691; 20843706; 20845079; 20855151; 20864363; 20887714; 20889295; 20921293; 20932173; 20936527; 20936699; 20937816; 20948207; 20963502; 20970160; 20977637; 21041295; 21041693; 21045016; 21048031; 21053100; 21086628; 21103065; 21104439; 21104440; 21116502; 21142815; 21145461; 21147512; 21148629; 21151391; 21165404; 21174062; 21174909; 21193558; 21205070; 21206012; 21212676; 21228795; 21229878; 21248144; 21261731; 21264536; 21265099; 21276823; 21277149; 21307882; 21316839; 21331614; 21334717; 21336947; 21343160; 21344498; 21349701; 21359202; 21378341; 21393869; 21397857; 21401309; 21418186; 21421877; 21427648; 21432777; 21437624; 21453685; 21454822; 21461859; 21463121; 21471148; 21478099; 21483125; 21489023; 21503582; 21515251; 21516345; 21524920; 21526499; 21531813; 21541352; 21541674; 21565179; 21569377; 21574189; 21575462; 21576412; 21590355; 21611838; 21612407; 21620625; 21620672; 21624249; 21624510; 21627988; 21630198; 21637818; 21641389; 21656154; 21661398; 21667117; 21681346; 21687932; 21694463; 21705840; 21707819; 21712445; 21721010; 21722821; 21723775; 21734530; 21735328; 21745270; 21750404; 21756063; 21760911; 21764444; 21777461; 21782323; 21784671; 21794897; 21813640; 21820153; 21839835; 21842128; 21857898; 21858102; 21858104; 21880183; 21889192; 21901248; 21908153; 21909361; 21924036; 21928345; 21938405; 21956669; 21957576; 21958210; 21965295; 21968416; 21969874; 21989104; 21993452; 22006368; 22010139; 22020421; 22024074; 22030137; 22072145; 22082680; 22094096; 22110735; 22117411; 22169692; 22199296; 22200256; 22200661; 22200690; 22200710; 22204652; 22212960; 22227305; 22237453; 22252755; 22286800; 22288519; 22289521; 22291969; 22302011; 22303700; 22309692; 22323339; 22327101; 22327326; 22336124; 22342364; 22349830; 22374248; 22391064; 22396544; 22402435; 22406112; 22428754; 22448134; 22451655; 22455335; 22460086; 22472880; 22490679; 22490851; 22493443; 22509276; 22513045; 22513785; 22515887; 22519916; 22522455; 22527932; 22527933; 22531681; 22532131; 22534113; 22534634; 22546345; 22550139; 22551568; 22577146; 22580443; 22590832; 22591362; 22618590; 22634718; 22642972; 22646815; 22651889; 22652796; 22659470; 22669775; 22672240; 22684547; 22694915; 22707264; 22727191; 22783577; 22785600; 22820140; 22835601; 22836342; 22846578; 22848537; 22863019; 22865631; 22876575; 22883193; 22883459; 22898815; 22901190; 22931588; 22936257; 22938472; 22951829; 22959677; 22960198; 22964525; 22968857; 22985025; 23005037; 23006733; 23013132; 23038275; 23043936; 23057632; 23059760; 23064462; 23093058; 23096596; 23098370; 23100088; 23107277; 23107342; 23114726; 23134156; 23136827; 23146278; 23158991; 23164104; 23166329; 23171686; 23184003; 23201304; 23205572; 23220260; 23232575; 23242659; 23254288; 23257253; 23261429; 23264224; 23271497; 23271813; 23273944; 23280016; 23292837; 23306155; 23313298; 23320481; 23333895; 23343958; 23349885; 23357697; 23364396; 23375518; 23378725; 23381805; 23384723; 23387827; 23388341; 23388475; 23390835; 23395821; 23412981; 23424616; 23428182; 23440286; 23465389; 23494562; 23498792; 23510467; 23510472; 23516489; 23544610; 23557756; 23559867; 23566884; 23577575; 23588386; 23613407; 23623988; 23637955; 23650722; 23651923; 23660954; 23661021; 23661254; 23663265; 23673111; 23676485; 23685894; 23696025; 23696797; 23705892; 23716178; 23725476; 23736018; 23737137; 23763335; 23766685; 23768069; 23773714; 23791966; 23793312; 23796708; 23807209; 23814095; 23814098; 23817219; 23819399; 23832737; 23847438; 23852912; 23855590; 23870474; 23886165; 23897811; 23915070; 23915071; 23922934; 23936390; 24037915; 24047437; 24062440; 24067484; 24122234; 24164447; 24297171; 24335416; 24344010; 24374173; 24479343; 24479348 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) Ensembl:ENSG00000087245 HGNC:7166 HPRD:00386 MIM:120360 Vega:OTTHUMG00000133202 MMP2 Bin Zhao, Yue Liu, Oliver He CHDS6 MMP-3 SL-1 STMY STMY1 STR1 WEB: http://www.ncbi.nlm.nih.gov/gene MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) 4314 11q22.3 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0004222 (EC: IEA); GO_0005509 (EC: IEA); GO_0005576 (EC: TAS); GO_0005578 (EC: IEA); GO_0005615 (EC: TAS, PMID: 3360803); GO_0006508 (EC: TAS, PMID: 3360803); GO_0008270 (EC: IEA); GO_0022617 (EC: TAS); GO_0030198 (EC: TAS); GO_0030334 (EC: IEA); GO_0030574 (EC: TAS); GO_0071230 (EC: IEA) PMID: 2383557; 2605216; 2785989; 3030290; 3360803; 3477804; 7523391; 7656014; 7694569; 7998967; 8125298; 8216228; 8486377; 8535233; 8662692; 8740360; 8921407; 8957070; 9083493; 9148753; 9288970; 9548733; 9558113; 9733482; 9737711; 9760240; 9792098; 9827994; 9873489; 9888835; 10419448; 10422833; 10543949; 10639284; 10669564; 10877850; 10922468; 10947989; 10967118; 10986281; 11116068; 11297453; 11327577; 11375993; 11380116; 11438501; 11485914; 11546917; 11751414; 11824472; 11827795; 11836255; 11841344; 11841844; 11977998; 11982752; 11988625; 12009331; 12034345; 12034715; 12054564; 12054629; 12071839; 12103254; 12124858; 12149192; 12204805; 12205736; 12229968; 12230559; 12364729; 12385578; 12432557; 12473595; 12477932; 12477941; 12485468; 12572877; 12634064; 12651627; 12727228; 12736398; 12750310; 12761889; 12784383; 12810672; 12821236; 12832381; 12834347; 12837283; 12866026; 12867428; 12876636; 12880418; 12952836; 13129650; 14712311; 14715248; 14718574; 14984923; 14998290; 15009479; 15033492; 15070833; 15084374; 15094779; 15102660; 15142265; 15161710; 15172469; 15194213; 15203551; 15234427; 15274394; 15288468; 15290728; 15308783; 15312099; 15319295; 15319302; 15337261; 15342709; 15355616; 15383690; 15389640; 15467919; 15474069; 15489334; 15528217; 15529384; 15546966; 15610507; 15640153; 15665388; 15667946; 15701845; 15716694; 15748780; 15757531; 15763339; 15788677; 15823277; 15863497; 15879464; 15894268; 15944607; 15955221; 15972662; 15993717; 16080875; 16082623; 16088212; 16100452; 16102106; 16158251; 16202315; 16238676; 16278009; 16302209; 16311244; 16323393; 16356191; 16405530; 16424284; 16430740; 16516860; 16532917; 16615041; 16629857; 16677108; 16739355; 16802342; 16822591; 16871440; 16899023; 16904077; 16905683; 16919028; 16935611; 16937230; 16972019; 16972255; 16972994; 16984617; 16998253; 17000679; 17000887; 17003494; 17024375; 17027562; 17033924; 17058024; 17065356; 17077200; 17125518; 17137622; 17145822; 17151781; 17178858; 17181997; 17182940; 17198194; 17207965; 17316652; 17316907; 17319946; 17320799; 17373931; 17381556; 17383306; 17434489; 17436000; 17471097; 17473191; 17502998; 17530713; 17537400; 17543900; 17559909; 17564313; 17589947; 17607721; 17617834; 17617837; 17664256; 17669621; 17672933; 17703334; 17710450; 17719307; 17763214; 17763953; 17765638; 17875574; 17893005; 17901377; 17911432; 17919326; 17922906; 17929133; 17942123; 17958893; 17975717; 18006768; 18007247; 18028894; 18029348; 18035073; 18063811; 18076359; 18077489; 18091353; 18172013; 18212480; 18220784; 18225577; 18234553; 18237197; 18262287; 18275497; 18303200; 18308831; 18342317; 18363112; 18426080; 18445105; 18469698; 18485900; 18496696; 18513389; 18541955; 18566588; 18571835; 18573993; 18606478; 18609140; 18619594; 18634015; 18636124; 18674944; 18674955; 18760468; 18801353; 18810583; 18818437; 18818748; 18830194; 18974705; 19005290; 19008710; 19019335; 19019896; 19042922; 19056482; 19064570; 19065524; 19100060; 19131662; 19132754; 19155066; 19159011; 19165649; 19180518; 19212832; 19221176; 19238444; 19245826; 19263529; 19268777; 19275880; 19279308; 19293200; 19318431; 19321798; 19336475; 19337798; 19376102; 19381070; 19432148; 19435861; 19438845; 19479237; 19504098; 19507017; 19507256; 19508478; 19522160; 19527514; 19551141; 19559392; 19576586; 19578796; 19585142; 19614693; 19628284; 19643940; 19664242; 19678938; 19690958; 19729601; 19731200; 19762026; 19770597; 19778329; 19786072; 19789190; 19834535; 19836620; 19843588; 19892918; 19906289; 19913121; 19923455; 19948975; 19949639; 20009418; 20031604; 20038976; 20082876; 20092902; 20113256; 20142115; 20204402; 20211321; 20215736; 20302034; 20346360; 20359947; 20360864; 20374310; 20385826; 20435584; 20436380; 20437586; 20452482; 20453000; 20455995; 20467172; 20472558; 20483790; 20484597; 20485444; 20538124; 20541269; 20574775; 20584750; 20587546; 20609072; 20609440; 20616161; 20616708; 20622166; 20628086; 20628624; 20630073; 20640910; 20654099; 20655856; 20672350; 20673868; 20707923; 20708412; 20731042; 20740392; 20802378; 20822909; 20827277; 20832538; 20853681; 20873121; 20935575; 20936527; 20942234; 20948207; 20959880; 21037509; 21044079; 21048031; 21103065; 21108787; 21111627; 21113741; 21134112; 21150162; 21183746; 21187770; 21190865; 21206012; 21212676; 21219546; 21227015; 21228692; 21232745; 21244504; 21247370; 21277817; 21321996; 21330369; 21336947; 21345293; 21357403; 21431945; 21443102; 21451793; 21454617; 21454822; 21481333; 21601886; 21667159; 21707906; 21753786; 21770773; 21782982; 21802713; 21853476; 21867693; 21871427; 21872914; 21900582; 21917825; 21925226; 21935932; 21948134; 22027013; 22057989; 22089392; 22092736; 22114952; 22121090; 22122951; 22134873; 22175304; 22184093; 22204652; 22207289; 22210296; 22222271; 22241750; 22265821; 22278305; 22314025; 22441965; 22455335; 22457004; 22515887; 22531699; 22587600; 22628530; 22671570; 22730240; 22776467; 22786680; 22819245; 22832961; 22836729; 22862420; 22868188; 22888638; 22890115; 22922035; 22927007; 22965799; 22975753; 23043898; 23100088; 23108733; 23123160; 23128460; 23328930; 23343931; 23357697; 23377317; 23409137; 23412981; 23483952; 23509928; 23522322; 23548063; 23564449; 23575435; 23608488; 23637955; 23696797; 23705892; 23707809; 23769926; 23794948; 23872201; 23922934; 23926017; 23934131; 23978194; 24338609 matrix metallopeptidase 3 (stromelysin 1, progelatinase) Ensembl:ENSG00000149968 HGNC:7173 HPRD:01703 MIM:185250 Vega:OTTHUMG00000048254 MMP3 Bin Zhao, Yue Liu, Oliver He CLG4B GELB MANDP2 MMP-9 WEB: http://www.ncbi.nlm.nih.gov/gene MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 4318 20q11.2-q13.1 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0001501 (EC: IEA); GO_0001503 (EC: IEA); GO_0004222 (EC: IDA, PMID: 16192646); GO_0005515 (EC: IPI, PMID: 16512877); GO_0005518 (EC: TAS, PMID: 2251898); GO_0005576 (EC: TAS); GO_0005578 (EC: IEA); GO_0005615 (EC: IDA, PMID: 2251898); GO_0006508 (EC: IDA, PMID: 2551898); GO_0007566 (EC: IEA); GO_0008270 (EC: TAS, PMID: 2251898); GO_0022617 (EC: TAS); GO_0030198 (EC: TAS); GO_0030225 (EC: TAS, PMID: 2251898); GO_0030574 (EC: TAS); GO_0042802 (EC: IPI); GO_0043065 (EC: IEA); GO_0050900 (EC: IEA); GO_0051549 (EC: IMP, PMID: 17704059) PMID: 1281792; 1371271; 1400481; 1645657; 1653055; 1653238; 1851724; 1932376; 2158484; 2251898; 2551898; 7669817; 7694569; 7762981; 7896811; 8012988; 8216228; 8426746; 8568270; 8691515; 8978762; 9261109; 9268487; 9344465; 9360944; 9378998; 9578462; 9590175; 9789069; 9878537; 10095777; 10339412; 10389762; 10419448; 10580107; 10598806; 10636480; 10642956; 10644727; 10652271; 10706134; 10796887; 10859319; 10900205; 10988146; 11023497; 11081634; 11134254; 11168762; 11179305; 11279011; 11410119; 11468147; 11486009; 11546917; 11557670; 11576356; 11606713; 11675412; 11688724; 11708786; 11742492; 11756567; 11780052; 11781819; 11813159; 11827795; 11827968; 11830485; 11833938; 11839588; 11839746; 11854622; 11875051; 11876767; 11890521; 11916008; 11920503; 11920505; 11935310; 11940298; 11956628; 11958288; 11971760; 11978564; 11986939; 11994547; 11999552; 12004062; 12029498; 12034345; 12050187; 12051944; 12054499; 12062817; 12063180; 12077439; 12081477; 12082590; 12082592; 12084167; 12103254; 12105194; 12126625; 12127674; 12183836; 12193399; 12205736; 12208863; 12219015; 12231534; 12235127; 12235151; 12356580; 12372334; 12376362; 12398893; 12414663; 12431239; 12431981; 12437116; 12443715; 12444074; 12452001; 12464265; 12471459; 12477932; 12479097; 12479099; 12559990; 12569569; 12586837; 12587534; 12589095; 12606037; 12612199; 12615834; 12626459; 12642591; 12651627; 12663332; 12668489; 12671895; 12704537; 12712078; 12717622; 12717827; 12724312; 12727228; 12728308; 12745093; 12750540; 12753719; 12769333; 12789238; 12791318; 12810681; 12811828; 12824186; 12830465; 12847101; 12850503; 12861851; 12865405; 12866035; 12874388; 12879005; 12880418; 12914776; 12921631; 12947332; 12949792; 12950257; 12952836; 12958623; 12960156; 12960961; 12967855; 12970724; 14500349; 14520690; 14550288; 14550924; 14551878; 14561155; 14581136; 14605329; 14607966; 14624478; 14633819; 14644158; 14661062; 14661256; 14675172; 14676438; 14681642; 14687896; 14697951; 14705229; 14719079; 14744773; 14766231; 14767860; 14963289; 14973177; 14981939; 14982353; 14983226; 14990702; 15009705; 15015767; 15022328; 15033492; 15034761; 15064242; 15067014; 15070833; 15075244; 15084374; 15085249; 15094060; 15105396; 15118287; 15122332; 15123665; 15131051; 15132991; 15146197; 15165255; 15169910; 15191941; 15201662; 15204835; 15212936; 15214991; 15223247; 15239215; 15241180; 15247301; 15248826; 15254682; 15256791; 15265790; 15271946; 15277439; 15288392; 15311942; 15313474; 15316122; 15327032; 15328199; 15356679; 15363817; 15363818; 15384859; 15385524; 15449075; 15465610; 15489334; 15498369; 15522165; 15528190; 15531749; 15531921; 15536155; 15541021; 15556929; 15557756; 15565457; 15569994; 15583828; 15585220; 15604254; 15609121; 15609318; 15628723; 15642145; 15652414; 15672417; 15691353; 15748780; 15754326; 15754388; 15760647; 15760679; 15797648; 15800029; 15809093; 15820246; 15823277; 15824107; 15824527; 15826319; 15831558; 15834245; 15848174; 15855236; 15863510; 15866216; 15885317; 15888067; 15896974; 15904490; 15924675; 15935515; 15944607; 15947272; 15949868; 15952124; 15955221; 15956726; 15998676; 16005367; 16023005; 16026590; 16042227; 16054858; 16061701; 16061852; 16061858; 16080811; 16082623; 16083752; 16086239; 16097959; 16100452; 16102725; 16114056; 16126934; 16133529; 16135959; 16140265; 16155381; 16158251; 16159601; 16166639; 16168399; 16177394; 16179285; 16191301; 16192641; 16192646; 16202218; 16213873; 16237750; 16246065; 16248458; 16248506; 16260653; 16267613; 16272296; 16278009; 16280123; 16288746; 16291395; 16301860; 16313894; 16331612; 16338908; 16339461; 16356191; 16359987; 16372907; 16395864; 16405530; 16413616; 16426593; 16429190; 16432074; 16455621; 16456793; 16463672; 16467043; 16469801; 16476613; 16512877; 16514055; 16516857; 16528670; 16551853; 16574900; 16585124; 16596205; 16615041; 16615109; 16619037; 16631427; 16638593; 16643654; 16652230; 16670311; 16672230; 16674956; 16676616; 16678588; 16690896; 16700817; 16709939; 16718267; 16720051; 16722933; 16732316; 16733654; 16736997; 16739355; 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23085464; 23091417; 23100088; 23104504; 23107277; 23107342; 23110201; 23114726; 23122824; 23123160; 23128233; 23134156; 23136157; 23146278; 23150684; 23151854; 23170789; 23175213; 23176145; 23179648; 23182966; 23183822; 23190621; 23201304; 23213753; 23221126; 23229548; 23232575; 23238437; 23240894; 23249715; 23252412; 23257253; 23257658; 23258534; 23263825; 23264211; 23269605; 23271730; 23273944; 23288142; 23292863; 23295196; 23303633; 23306155; 23307113; 23313298; 23317273; 23320481; 23326131; 23328249; 23341882; 23343958; 23349885; 23350235; 23353996; 23356642; 23372434; 23373240; 23375032; 23377317; 23387490; 23387827; 23388475; 23390835; 23401127; 23401274; 23409137; 23441116; 23454149; 23456480; 23476138; 23490413; 23504993; 23509357; 23510467; 23510472; 23516489; 23525277; 23525523; 23526143; 23536722; 23544610; 23547785; 23550278; 23554968; 23555986; 23557756; 23559867; 23566884; 23570558; 23575435; 23580092; 23601700; 23606791; 23615401; 23617547; 23637955; 23639553; 23650722; 23657566; 23660954; 23661254; 23663265; 23673111; 23679245; 23681803; 23696797; 23696833; 23697266; 23708302; 23715826; 23725476; 23742776; 23762835; 23768069; 23770289; 23770367; 23792205; 23793312; 23794948; 23801886; 23805466; 23807209; 23807291; 23814095; 23819814; 23824974; 23825535; 23829879; 23847438; 23870474; 23886165; 23897811; 23901237; 23908067; 23922934; 23936495; 23987197; 23991961; 23993112; 24025248; 24039251; 24065232; 24067484; 24072693; 24075964; 24099107; 24099425; 24122234; 24136650; 24141084; 24174628; 24210229; 24291031; 24297171; 24326842; 24330623; 24335416; 24344010; 24344026; 24374173; 24479343; 24479348 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) Ensembl:ENSG00000100985 HGNC:7176 HPRD:00387 MIM:120361 Vega:OTTHUMG00000033044 MMP9 Bin Zhao, Yue Liu, Oliver He SL-2 STMY2 WEB: http://www.ncbi.nlm.nih.gov/gene MMP10 matrix metallopeptidase 10 (stromelysin 2) 4319 11q22.3 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0004222 (EC: IEA); GO_0005509 (EC: IEA); GO_0005576 (EC: TAS); GO_0005578 (EC: IEA); GO_0005615 (EC: TAS, PMID: 2844164); GO_0006508 (EC: TAS, PMID: 2844164); GO_0008270 (EC: IEA); GO_0022617 (EC: TAS); GO_0030198 (EC: TAS); GO_0030334 (EC: IEA); GO_0030574 (EC: TAS) PMID: 1874716; 2369069; 2605216; 2844164; 7632822; 7694569; 8003069; 8125298; 8144618; 8349617; 8631328; 8921407; 9042108; 9261109; 9427548; 9578462; 9662124; 10419448; 10472874; 10986281; 12477932; 15095982; 15288123; 15371548; 15375490; 15489334; 15944607; 16054593; 16331256; 16516860; 16580524; 17009259; 17543340; 17695449; 18035073; 18427549; 18617643; 19317417; 19489686; 19601983; 19695094; 19762781; 19913121; 19921252; 19935709; 20215736; 20219015; 20432469; 20452482; 20453000; 20484597; 20584750; 20587546; 20628086; 20673868; 20936527; 21925226; 21998657; 22022614; 22104553; 22121946; 22427646; 22492089; 22524815; 22545096; 22821423; 23098370; 23412934; 23535732; 23742289; 24255036; 24327153 matrix metallopeptidase 10 (stromelysin 2) Ensembl:ENSG00000166670 HGNC:7156 HPRD:01704 MIM:185260 Vega:OTTHUMG00000168083 MMP10 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene MPO myeloperoxidase 4353 17q23.1 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0001878 (EC: IEA); GO_0002149 (EC: IEA); GO_0002679 (EC: IEA); GO_0003682 (EC: TAS, PMID: 2829220); GO_0004601 (EC: IDA, PMID: 10772654); GO_0005615 (EC: IDA, PMID: 10772654); GO_0005634 (EC: TAS, PMID: 2829220); GO_0005739 (EC: IEA); GO_0005764 (EC: TAS, PMID: 8621627); GO_0006952 (EC: TAS, PMID: 8621627); GO_0006979 (EC: TAS, PMID: 2903767); GO_0007568 (EC: IEA); GO_0008201 (EC: IDA, PMID: 11907569); GO_0009612 (EC: IEA); GO_0019430 (EC: IEA); GO_0020037 (EC: IEA); GO_0030141 (EC: IDA, PMID: 11907569); GO_0032094 (EC: IEA); GO_0032496 (EC: IEA); GO_0034374 (EC: IDA, PMID: 10772654); GO_0042582 (EC: IDA, PMID: 2981589); GO_0042744 (EC: IDA, PMID: 10772654); GO_0043066 (EC: TAS, PMID: 10801811); GO_0044130 (EC: IEA); GO_0046872 (EC: IEA); GO_0050832 (EC: IEA); GO_0055114 (EC: IDA, PMID: 10772654); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1320128; 1334087; 1703177; 2154223; 2444596; 2552418; 2820530; 2829220; 2884926; 2903767; 2981589; 3029127; 3031585; 3654979; 7530510; 7809065; 7840679; 7904599; 8037771; 8078496; 8142659; 8383257; 8390465; 8530055; 8621627; 8718890; 9097926; 9175709; 9354683; 9637725; 10766826; 10772654; 10777476; 10801811; 10828600; 11087769; 11090610; 11147929; 11161635; 11179831; 11423389; 11434421; 11705390; 11774269; 11794452; 11811524; 11813987; 11840286; 11861298; 11895912; 11907569; 11943609; 11956078; 11960308; 11981455; 11986950; 12027420; 12052532; 12057865; 12089442; 12111688; 12135010; 12164325; 12209361; 12355548; 12393699; 12397651; 12432558; 12460800; 12477932; 12496042; 12496043; 12515618; 12565898; 12606047; 12694338; 12707270; 12729191; 12773517; 12782337; 12792137; 12800195; 12810834; 12818404; 12861032; 12915675; 12946561; 12950060; 12952835; 12969520; 14580687; 14617020; 14626895; 14646692; 14668325; 14716779; 14729580; 14730210; 14761515; 14972011; 15006595; 15023809; 15031357; 15068388; 15108282; 15159316; 15184258; 15196853; 15199549; 15203186; 15222689; 15255951; 15299090; 15304260; 15331175; 15350145; 15379210; 15492293; 15504976; 15507752; 15507753; 15507754; 15507759; 15507760; 15507769; 15507770; 15507771; 15536330; 15538122; 15600254; 15661916; 15705913; 15714076; 15718477; 15734083; 15829318; 15850382; 15884126; 15885363; 15894800; 15901995; 15911707; 15967795; 15996936; 16084535; 16107886; 16148002; 16157195; 16170238; 16195240; 16221222; 16267254; 16289072; 16297214; 16326702; 16335952; 16385446; 16430221; 16476719; 16484808; 16497665; 16504169; 16543247; 16606792; 16641309; 16732739; 16740002; 16758302; 16829688; 16844322; 16883063; 16901848; 16956579; 17017121; 17042493; 17119198; 17145829; 17149600; 17159117; 17161406; 17178637; 17209550; 17259657; 17304047; 17337886; 17355643; 17381162; 17424838; 17428572; 17438335; 17440118; 17451207; 17479404; 17483704; 17521322; 17549373; 17582430; 17595772; 17601350; 17613595; 17650507; 17701359; 17704068; 17726014; 17767014; 17855424; 17869258; 17875305; 17885617; 17896805; 17922231; 17925548; 17980933; 18042261; 18051367; 18177875; 18205184; 18214807; 18237195; 18258609; 18271379; 18273043; 18280811; 18296681; 18314009; 18322643; 18331758; 18340529; 18344624; 18359301; 18435917; 18440308; 18441517; 18447907; 18452102; 18466756; 18505072; 18617697; 18632753; 18636124; 18642288; 18662591; 18667997; 18676680; 18676870; 18778866; 18784359; 18836923; 18854777; 18930040; 18976975; 18977241; 19012698; 19030913; 19031316; 19056867; 19059911; 19081093; 19126404; 19129321; 19138806; 19140875; 19147137; 19162321; 19170196; 19201174; 19237222; 19255063; 19255975; 19322015; 19339270; 19345674; 19362143; 19410253; 19420105; 19423521; 19423540; 19479063; 19490915; 19505917; 19524564; 19538950; 19543083; 19544176; 19556446; 19578796; 19589271; 19593802; 19608745; 19614918; 19622717; 19625176; 19626395; 19641039; 19646343; 19651119; 19651670; 19692168; 19726691; 19729473; 19729601; 19731237; 19735726; 19752340; 19758957; 19761988; 19788922; 19789190; 19814685; 19816870; 19822138; 19828014; 19857655; 19857676; 19877306; 19878569; 19897513; 19902075; 19913121; 19916937; 19963114; 19995403; 20007081; 20026093; 20032816; 20043647; 20064972; 20080069; 20091863; 20136960; 20146436; 20158910; 20201999; 20228064; 20237496; 20301340; 20305551; 20332087; 20332596; 20360068; 20364045; 20364135; 20399194; 20406964; 20413430; 20418356; 20437850; 20438785; 20485444; 20536280; 20568015; 20592714; 20598694; 20628086; 20636397; 20643115; 20644561; 20646231; 20651370; 20663217; 20673159; 20673504; 20677014; 20714866; 20732340; 20848159; 20933108; 20951227; 20974672; 20974816; 21126969; 21176345; 21204009; 21292302; 21327394; 21331575; 21407237; 21461569; 21540635; 21657847; 21674360; 21699462; 21739466; 21779191; 21792769; 21795425; 21827295; 21856025; 21880315; 21880720; 21884783; 21907168; 21917261; 21934609; 21950958; 21967851; 22014237; 22094928; 22097722; 22126566; 22140557; 22145905; 22219194; 22264587; 22331023; 22352991; 22355012; 22427832; 22462773; 22465269; 22659527; 22703762; 22739978; 22802447; 22902565; 22912422; 22949765; 22959522; 22985908; 23016839; 23066164; 23124356; 23167629; 23268804; 23306200; 23342893; 23364307; 23436245; 23532856; 23535901; 23537682; 23583798; 23620142; 23624305; 23666398; 23691142; 23707661; 23734221; 23746122; 23773345; 23832536; 23840365; 23893381; 23908111; 23943394; 23979979; 24035742 myeloperoxidase MPO Bin Zhao, Yue Liu, Oliver He MST TST2 WEB: http://www.ncbi.nlm.nih.gov/gene MPST mercaptopyruvate sulfurtransferase 4357 LL22NC01-146D10.4 22q13.1 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0004792 (EC: IEA); GO_0005739 (EC: IEA); GO_0009440 (EC: TAS, PMID: 9070219); GO_0009636 (EC: TAS, PMID: 9070219); GO_0016784 (EC: IEA); GO_0030054 (EC: IEA); GO_0043005 (EC: ISS); GO_0045202 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070814 (EC: ISS) PMID: 1953758; 9070219; 10591208; 12477932; 14702039; 15461802; 15489334; 16545926; 18029348; 19056867; 19615732; 19695240; 20446008; 20877624; 21906983; 21963094; 22505724; 22939629; 23000965; 23698001 mercaptopyruvate sulfurtransferase Ensembl:ENSG00000128309 HGNC:7223 HPRD:11896 MIM:602496 Vega:OTTHUMG00000150543 MPST Bin Zhao, Yue Liu, Oliver He PMSR WEB: http://www.ncbi.nlm.nih.gov/gene MSRA methionine sulfoxide reductase A 4482 8p23.1 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0005634 (EC: IEA); GO_0005739 (EC: IEA); GO_0006464 (EC: TAS, PMID: 10452521); GO_0006555 (EC: TAS, PMID: 10452521); GO_0006979 (EC: IEA); GO_0008113 (EC: IEA); GO_0016020 (EC: IEA); GO_0030091 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 8622914; 10452521; 12039877; 12477932; 12693988; 14759519; 15199188; 15489334; 15680232; 16162094; 16257642; 16364291; 16480945; 17601350; 17784942; 17943184; 18506707; 18845237; 18977241; 19056867; 19085252; 19237503; 19430479; 19542914; 19557161; 19747232; 19844733; 19913121; 20368336; 20379614; 20421936; 20452100; 20617525; 20628086; 20689807; 20703240; 20724581; 20877624; 20937881; 21079812; 21139048; 21674055; 21679298; 21890473; 22438829; 22634633; 22657383; 22688191; 22867795; 23049088; 23244167; 23415806; 23568457; 24250222 methionine sulfoxide reductase A Ensembl:ENSG00000175806 HGNC:7377 HPRD:03152 MIM:601250 Vega:OTTHUMG00000090517 MSRA Bin Zhao, Yue Liu, Oliver He COI MTCO1 WEB: http://www.ncbi.nlm.nih.gov/gene MT-CO1 mitochondrially encoded cytochrome c oxidase I 4512 20140408 9606 MT protein-coding Official from a nomenclature committee PMID: 7219534; 10508508; 11345519; 11849212; 12140182; 14607829; 14759509; 15036329; 15308583; 15931342; 16002321; 16335786; 16671096; 16740593; 17341490; 17357124; 17559347; 17893145; 18204294; 18251004; 18484665; 18624398; 18705313; 18718066; 19050702; 19147801; 19267350; 19570036; 19758471; 20301403; 20301411; 20301595; 20301607; 20382059; 20936779; 21139048; 21301321; 21389643; 21621438; 21988832; 22252130; 22356826; 22419111; 22927926; 22972377; 22990118; 23030649; 23088713; 23509693; 23712756; 24333447 cytochrome c oxidase subunit I HGNC:7419 MIM:516030 COX1 Bin Zhao, Yue Liu, Oliver He COII MTCO2 WEB: http://www.ncbi.nlm.nih.gov/gene MT-CO2 mitochondrially encoded cytochrome c oxidase II 4513 20140408 9606 MT protein-coding Official from a nomenclature committee PMID: 7219534; 10194136; 10508508; 11849212; 12031622; 12115729; 12732844; 14607829; 15254227; 15282306; 15308583; 15316498; 15931342; 15965049; 16288875; 17353931; 17500595; 17578348; 17616393; 17619138; 17727817; 17916073; 18224252; 18261751; 18294142; 18314621; 18409190; 18509181; 19050702; 19066432; 19133256; 19295170; 19336478; 19738201; 19758471; 19771519; 19840943; 20034753; 20117988; 20186120; 20301403; 20301411; 20354817; 20401641; 20471030; 20645029; 20934379; 20936779; 20960565; 21069476; 21092633; 21139048; 21301321; 21319273; 21417982; 21424030; 21625016; 21734188; 21782872; 21809666; 21813027; 21840784; 21849808; 21854221; 21857970; 21858104; 21858117; 21890473; 21907277; 21957142; 21984126; 21988832; 22145905; 22170686; 22234093; 22241583; 22252130; 22262461; 22419111; 22487732; 22588264; 22748678; 22870593; 22990118; 23177619; 24061460 cytochrome c oxidase subunit II HGNC:7421 MIM:516040 COX2 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 4524 RP11-56N19.4 1p36.3 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001666 (EC: IEA); GO_0004489 (EC: TAS); GO_0005829 (EC: TAS); GO_0006520 (EC: TAS, PMID: 7647779); GO_0006766 (EC: TAS); GO_0006767 (EC: TAS); GO_0008015 (EC: TAS, PMID: 7647779); GO_0009086 (EC: IEA); GO_0033274 (EC: IEA); GO_0035999 (EC: IEA); GO_0042493 (EC: IEA); GO_0043005 (EC: IEA); GO_0044281 (EC: TAS); GO_0046500 (EC: IEA); GO_0046655 (EC: TAS); GO_0050660 (EC: IEA); GO_0050661 (EC: IEA); GO_0050667 (EC: IDA); GO_0051593 (EC: IEA); GO_0070555 (EC: IEA); GO_0072341 (EC: IDA) PMID: 7647779; 7726158; 7920641; 7951330; 8895734; 8940272; 9545395; 9545406; 9680386; 9719624; 9781030; 10536004; 10679944; 10791559; 11018168; 11022077; 11024398; 11025596; 11048629; 11054348; 11056246; 11058711; 11062308; 11073851; 11074490; 11074524; 11080594; 11084577; 11085290; 11092508; 11094304; 11096266; 11096270; 11098041; 11101473; 11108898; 11118403; 11121176; 11122096; 11124649; 11128675; 11133719; 11142765; 11146461; 11150582; 11155296; 11157318; 11161947; 11168435; 11169021; 11170082; 11170083; 11177206; 11186937; 11197244; 11204578; 11204591; 11228493; 11252530; 11257266; 11257267; 11259808; 11268732; 11274015; 11274424; 11281306; 11282795; 11287760; 11292330; 11295130; 11299748; 11303187; 11303694; 11307798; 11309278; 11310576; 11319193; 11320983; 11323021; 11328206; 11330536; 11336184; 11341749; 11342344; 11342450; 11343335; 11349190; 11359462; 11360806; 11385320; 11386855; 11388660; 11395038; 11397354; 11418485; 11420199; 11423453; 11424140; 11426488; 11427218; 11431185; 11434083; 11436125; 11440783; 11443546; 11451544; 11454529; 11457468; 11464627; 11470464; 11471199; 11480782; 11484165; 11487538; 11494235; 11506076; 11507973; 11509014; 11522740; 11523237; 11531629; 11532106; 11555700; 11558898; 11562338; 11568114; 11569694; 11575217; 11583306; 11584084; 11589919; 11590551; 11592436; 11592445; 11605019; 11669477; 11672761; 11673296; 11680544; 11684547; 11692002; 11692165; 11696022; 11710708; 11711225; 11712321; 11714857; 11718053; 11721146; 11722155; 11734671; 11736945; 11738073; 11738277; 11739968; 11744407; 11744804; 11747974; 11749660; 11751445; 11758232; 11768721; 11776159; 11781870; 11794822; 11801474; 11806787; 11807890; 11807892; 11813127; 11815318; 11821270; 11823591; 11828266; 11843038; 11851723; 11860783; 11860891; 11870335; 11872199; 11872884; 11880124; 11889073; 11904614; 11913566; 11920232; 11925474; 11927833; 11928564; 11929966; 11933257; 11935469; 11938441; 11940092; 11943942; 11947914; 11950428; 11953142; 11961379; 11963567; 11979347; 11981642; 11993593; 12011160; 12013675; 12015064; 12015164; 12020105; 12027572; 12032275; 12033523; 12036535; 12038037; 12038776; 12039122; 12042167; 12042168; 12042290; 12042673; 12045051; 12049191; 12049616; 12052604; 12060127; 12080391; 12081832; 12082592; 12083967; 12087901; 12095808; 12097536; 12097662; 12107847; 12111380; 12115343; 12122980; 12123235; 12123675; 12133463; 12138370; 12143122; 12146133; 12154064; 12164325; 12165282; 12170465; 12180000; 12180076; 12180146; 12186157; 12187094; 12187113; 12194796; 12196500; 12196644; 12204804; 12214149; 12215845; 12218328; 12221667; 12232679; 12237638; 12356186; 12356947; 12364720; 12370778; 12380673; 12382154; 12384649; 12387655; 12400059; 12411076; 12413583; 12417280; 12419832; 12421498; 12428084; 12430180; 12431255; 12433726; 12439143; 12442281; 12446192; 12453860; 12454577; 12468767; 12469051; 12471611; 12473175; 12477932; 12480755; 12488908; 12496052; 12499324; 12514663; 12518110; 12522558; 12522678; 12529699; 12534444; 12540022; 12547903; 12560354; 12560871; 12570104; 12574198; 12576444; 12589326; 12590185; 12590188; 12590948; 12594357; 12600862; 12602921; 12605391; 12612987; 12614926; 12615788; 12618331; 12618332; 12623486; 12642343; 12644913; 12648076; 12649066; 12649184; 12651974; 12654508; 12661370; 12666851; 12667409; 12672676; 12672677; 12673279; 12673582; 12674333; 12679134; 12681883; 12684695; 12687650; 12689549; 12690011; 12690212; 12694231; 12705333; 12707953; 12709363; 12713146; 12716294; 12718576; 12724616; 12730409; 12730410; 12730722; 12738509; 12738713; 12746418; 12747590; 12747593; 12747601; 12757770; 12766148; 12775885; 12776270; 12784029; 12784186; 12796044; 12796225; 12797455; 12797595; 12801615; 12807760; 12810988; 12816682; 12826168; 12827651; 12833177; 12844196; 12855225; 12855226; 12871600; 12875914; 12877902; 12879654; 12883704; 12883749; 12889841; 12891167; 12897091; 12899665; 12901511; 12901638; 12907815; 12911562; 12914571; 12915598; 12923155; 12923861; 12927690; 12928053; 12928694; 12939653; 12949355; 12951177; 12956845; 12958073; 12964809; 12975018; 13678724; 14499487; 14504916; 14508198; 14521457; 14535593; 14556201; 14560345; 14569745; 14572159; 14572619; 14578131; 14580166; 14580229; 14581802; 14585765; 14585902; 14586640; 14594111; 14597244; 14603192; 14604831; 14607573; 14608052; 14608109; 14613740; 14614398; 14616766; 14632302; 14634838; 14638877; 14642003; 14644077; 14644226; 14647408; 14650352; 14652285; 14652356; 14656021; 14656945; 14660985; 14669168; 14669613; 14677097; 14677182; 14679361; 14688016; 14688536; 14693836; 14698652; 14704292; 14706682; 14716779; 14717963; 14727014; 14728017; 14734201; 14735580; 14737040; 14739536; 14742985; 14746952; 14763962; 14767907; 14973091; 14973104; 14977639; 14981981; 14994919; 15002923; 15003888; 15004488; 15007309; 15009479; 15010895; 15022402; 15033038; 15033905; 15040829; 15041282; 15044114; 15046559; 15051606; 15053827; 15054400; 15054427; 15059157; 15059614; 15060097; 15063140; 15068389; 15073531; 15073633; 15075078; 15076187; 15082892; 15091001; 15096570; 15097012; 15103709; 15109703; 15110890; 15111988; 15114595; 15114606; 15117811; 15121372; 15123333; 15126006; 15126103; 15130349; 15135249; 15135689; 15136061; 15138617; 15146197; 15150439; 15151507; 15154859; 15159311; 15161007; 15163465; 15171737; 15184272; 15192249; 15193960; 15198953; 15201366; 15207432; 15210385; 15214944; 15216546; 15217535; 15219943; 15221800; 15223011; 15224376; 15226090; 15226189; 15231125; 15231206; 15231747; 15244514; 15259035; 15272569; 15280126; 15286469; 15289170; 15289817; 15293282; 15298954; 15300362; 15301724; 15301885; 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22044028; 22052259; 22056717; 22074251; 22084413; 22084937; 22094326; 22101856; 22103601; 22103678; 22104130; 22106923; 22108397; 22116453; 22126575; 22126580; 22128864; 22132838; 22138544; 22144047; 22146089; 22147263; 22153546; 22154679; 22175539; 22175540; 22176285; 22187009; 22189445; 22193458; 22194208; 22197386; 22203923; 22209973; 22215214; 22217364; 22218157; 22222489; 22230335; 22237773; 22241680; 22265089; 22277556; 22277790; 22283972; 22286863; 22292644; 22296361; 22296369; 22303578; 22311035; 22313097; 22327825; 22329245; 22342879; 22350268; 22354693; 22361411; 22370724; 22373582; 22375042; 22375693; 22377704; 22377705; 22385294; 22386772; 22418991; 22424391; 22425007; 22440940; 22441130; 22450905; 22453148; 22457816; 22470444; 22475273; 22479380; 22486600; 22492374; 22498705; 22507617; 22512572; 22513795; 22524826; 22524840; 22528331; 22528943; 22533155; 22536880; 22536935; 22540831; 22554825; 22555977; 22576904; 22576927; 22594584; 22628232; 22642106; 22647417; 22653243; 22660520; 22664498; 22668858; 22669161; 22676332; 22688557; 22690662; 22706675; 22711309; 22713864; 22719222; 22721898; 22729883; 22739363; 22747749; 22762524; 22770603; 22773907; 22775456; 22782530; 22789065; 22799306; 22799374; 22807619; 22810649; 22813657; 22832733; 22842321; 22846211; 22847888; 22853296; 22856671; 22868813; 22875508; 22882325; 22885990; 22890010; 22890827; 22897803; 22901166; 22901193; 22901194; 22901202; 22902176; 22914556; 22917961; 22918664; 22924497; 22928696; 22933837; 22938410; 22938427; 22938732; 22940147; 22940753; 22943282; 22947400; 22959498; 22982411; 22992775; 22992862; 22997914; 23010533; 23029458; 23036708; 23039890; 23042008; 23054000; 23056029; 23056169; 23057736; 23061880; 23070908; 23076983; 23089924; 23090267; 23095111; 23095199; 23098468; 23098496; 23098497; 23098510; 23103710; 23107469; 23108747; 23123730; 23128422; 23145891; 23155246; 23161188; 23167392; 23174406; 23183238; 23183616; 23184002; 23186985; 23201418; 23201630; 23207285; 23217001; 23225055; 23227261; 23227498; 23229495; 23230240; 23237779; 23238545; 23244112; 23247802; 23255668; 23270270; 23273201; 23276705; 23285018; 23285094; 23285280; 23288205; 23289804; 23295071; 23298970; 23300023; 23314385; 23314883; 23318463; 23329275; 23336575; 23342883; 23346007; 23346725; 23353103; 23357458; 23359274; 23385809; 23391848; 23392576; 23393023; 23395424; 23401650; 23407049; 23422951; 23428159; 23429214; 23430981; 23431363; 23437053; 23444906; 23450474; 23456769; 23457501; 23458174; 23458876; 23459165; 23460600; 23463763; 23484733; 23489792; 23490201; 23508410; 23523621; 23526309; 23534584; 23534726; 23534741; 23536781; 23542077; 23544272; 23547211; 23547829; 23548428; 23578207; 23593147; 23608654; 23626689; 23631288; 23642756; 23649653; 23652803; 23659764; 23679298; 23685257; 23687437; 23692062; 23695205; 23697869; 23698160; 23725631; 23731042; 23736036; 23749065; 23760328; 23765760; 23772168; 23774147; 23811028; 23812728; 23819405; 23824729; 23827456; 23828072; 23838799; 23846111; 23846816; 23856949; 23858518; 23865383; 23874907; 23876493; 23897558; 23900311; 23901246; 23914427; 23915182; 23916622; 23933414; 23936976; 23954866; 23954881; 23983171; 24014085; 24014284; 24023349; 24063603; 24103477; 24130171; 24132589; 24140489; 24268703; 24308218; 24334125; 24341140; 24498831; 24522021; 24605633 methylenetetrahydrofolate reductase (NAD(P)H) MTHFR Bin Zhao, Yue Liu, Oliver He MTND1 WEB: http://www.ncbi.nlm.nih.gov/gene MT-ND1 mitochondrially encoded NADH dehydrogenase 1 4535 20140408 9606 MT protein-coding Official from a nomenclature committee PMID: 6402020; 7219534; 10508508; 11418099; 12100083; 12111463; 12133550; 12618962; 12670626; 12756609; 14580860; 14671420; 14680844; 14759509; 15038995; 15108120; 15110773; 15265369; 15466014; 15505787; 15533721; 15696471; 15860916; 15952130; 15975594; 16060290; 16137960; 16335786; 16414144; 16604388; 16759180; 16784756; 16828917; 16884381; 17035175; 17045122; 17200023; 17429906; 17434142; 17454741; 17562939; 17619138; 17684475; 17717444; 18082471; 18194667; 18239645; 18486613; 18502698; 18504678; 18513491; 18590963; 18679013; 18701018; 18709563; 19050702; 19066432; 19199242; 19199265; 19276764; 19324017; 19487983; 19527690; 19555656; 19758471; 19822128; 20137661; 20176558; 20197120; 20211276; 20301353; 20301403; 20301411; 20643099; 21139048; 21329181; 21625124; 21852384; 21988832; 22079202; 22241583; 22517755; 22653752; 22990118; 23464625; 23530560 NADH dehydrogenase, subunit 1 (complex I) HGNC:7455 MIM:516000 ND1 Bin Zhao, Yue Liu, Oliver He LRBP MK MVLK POROK3 WEB: http://www.ncbi.nlm.nih.gov/gene MVK mevalonate kinase 4598 12q24 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0004496 (EC: IDA, PMID: 1377680); GO_0004496 (EC: IMP, PMID: 10369261); GO_0004496 (EC: TAS); GO_0005524 (EC: IEA); GO_0005777 (EC: IDA, Qualifier: NOT, PMID: 14730012); GO_0005829 (EC: IDA, PMID: 14730012); GO_0005829 (EC: TAS); GO_0006695 (EC: IDA, PMID: 1377680); GO_0006695 (EC: TAS); GO_0008299 (EC: IDA, PMID: 14680974); GO_0019287 (EC: IEA); GO_0042802 (EC: IPI, PMID: 16189514); GO_0044281 (EC: TAS); GO_0050728 (EC: IMP, PMID: 16732551) PMID: 1356376; 1377680; 6255462; 8302606; 9146921; 9325256; 9392419; 9464248; 10369261; 10369262; 10401001; 10417275; 11111075; 11313768; 11313769; 12444096; 12477733; 12477932; 12634869; 14680974; 14702039; 14730012; 14749336; 15037710; 15188372; 15489334; 15536479; 16189514; 16234278; 16732551; 16806233; 17213252; 17978300; 18029348; 18193043; 18302342; 18494797; 18512793; 18660489; 18941711; 19060906; 19148283; 19487539; 19605566; 20159775; 20160193; 20194276; 20430392; 20677014; 20686565; 20714348; 20814828; 20864672; 20972250; 21044950; 21124859; 21139048; 21147848; 21430599; 21548022; 22038276; 22159817; 22271696; 22863883; 22939629; 22983302; 23834120; 24064360; 24084495 mevalonate kinase Ensembl:ENSG00000110921 HGNC:7530 HPRD:02015 MIM:251170 Vega:OTTHUMG00000169256 MVK Bin Zhao, Yue Liu, Oliver He NEDD-8 WEB: http://www.ncbi.nlm.nih.gov/gene NEDD8 neural precursor cell expressed, developmentally down-regulated 8 4738 14q12 20140408 9606 14 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 15988528); GO_0005634 (EC: IEA); GO_0005829 (EC: TAS); GO_0006357 (EC: IEA); GO_0006464 (EC: TAS, PMID: 9694792); GO_0006508 (EC: TAS, PMID: 9694792); GO_0006511 (EC: TAS, PMID: 9353319); GO_0007179 (EC: TAS); GO_0008104 (EC: IEA); GO_0009653 (EC: TAS, PMID: 9694792); GO_0014070 (EC: IEA); GO_0031625 (EC: IPI, PMID: 15694336); GO_0045116 (EC: IDA, PMID: 10500095); GO_0070062 (EC: IDA) PMID: 1378265; 8395831; 8889548; 9353319; 9694792; 9790970; 9857030; 10207026; 10217437; 10318914; 10500095; 10585493; 10587588; 10597293; 10713156; 10772955; 10828074; 11024059; 11027288; 11181995; 11259415; 11585840; 11675391; 11953428; 12215427; 12477932; 12481031; 12504025; 12554766; 12565873; 12646924; 12730221; 12740388; 12759363; 12816948; 14564014; 14673145; 14676825; 14690597; 14702039; 14757770; 15060148; 15107402; 15242646; 15489334; 15567417; 15694336; 15775960; 15988528; 16111684; 16169070; 16177058; 16196087; 16503656; 16620772; 16735510; 16861300; 16877356; 16964240; 16979187; 16980297; 16998474; 17098746; 17119158; 17132228; 17192413; 17206147; 17220875; 17318178; 17332328; 17353931; 17369817; 17438373; 17440617; 17543862; 17546054; 17549501; 17609381; 17660949; 17935801; 18096514; 18173839; 18247557; 18264111; 18274552; 18323857; 18627766; 18652489; 18723677; 18789977; 18805092; 18826954; 18851830; 19245792; 19281774; 19295130; 19328766; 19471022; 19615732; 19713960; 19784069; 20029837; 20101219; 20190741; 20554519; 20596523; 20603103; 20688984; 20847044; 20850415; 21119685; 21139048; 21145461; 21169563; 21193393; 21252943; 21316600; 21399617; 21474709; 21693764; 21765416; 21822215; 21887275; 21890473; 21906983; 21963094; 21987572; 22004789; 22069333; 22081073; 22095636; 22190034; 22268729; 22271254; 22370482; 22388932; 22405651; 22466964; 22474075; 22502714; 22505724; 22537386; 22573887; 22584050; 22612509; 22691497; 22767593; 22836579; 22863883; 22895816; 22939629; 22959436; 23000965; 23001041; 23105008; 23118980; 23175788; 23201271; 23209320; 23246961; 23267066; 23290524; 23300442; 23394999; 23401859; 23539442; 23554956; 23776465; 23812220; 23824602; 23936405; 24019527; 24076655; 24130483 neural precursor cell expressed, developmentally down-regulated 8 Ensembl:ENSG00000129559 HGNC:7732 HPRD:04412 MIM:603171 Vega:OTTHUMG00000029325 NEDD8 Bin Zhao, Yue Liu, Oliver He CAS-L CAS2 CASL CASS2 HEF1 WEB: http://www.ncbi.nlm.nih.gov/gene NEDD9 neural precursor cell expressed, developmentally down-regulated 9 4739 RP1-49G10.1 6p25-p24 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000922 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11827972); GO_0005634 (EC: IEA); GO_0005737 (EC: TAS, PMID: 9584194); GO_0005794 (EC: IEA); GO_0005819 (EC: TAS, PMID: 9584194); GO_0005925 (EC: IEA); GO_0005938 (EC: IEA); GO_0007010 (EC: NAS, PMID: 11827972); GO_0007067 (EC: IEA); GO_0007155 (EC: IEA); GO_0007165 (EC: TAS, PMID: 8668148); GO_0007229 (EC: NAS, PMID: 11827972); GO_0030027 (EC: IEA); GO_0040008 (EC: IEA); GO_0051017 (EC: NAS, PMID: 11827972) PMID: 8668148; 8879209; 9020138; 9162067; 9295052; 9360983; 9366405; 9405482; 9497377; 9498705; 9584194; 9748319; 9820532; 10455189; 10490968; 10502414; 10508479; 10692442; 10808124; 10866674; 11054566; 11118211; 11438665; 11782456; 11827972; 12189134; 12477932; 12517963; 12522270; 12847683; 15051726; 15144186; 15144564; 15231748; 15342556; 15376324; 15489334; 15592516; 16184168; 16344118; 16344560; 16352661; 16394104; 17604723; 17703068; 17908996; 18063669; 18465784; 18579580; 18585997; 18624398; 19103205; 19275884; 19417561; 19539609; 19648964; 20068165; 20379614; 20413850; 20428794; 20430066; 20498643; 20534741; 21059344; 21139048; 21145356; 21317929; 21399483; 21765937; 21829474; 21832049; 21906983; 22061964; 22174851; 22328516; 22447485; 22732573; 22810897; 22869051; 22963925; 23037767; 23074285; 23086683; 23247867; 23355420; 24439227 neural precursor cell expressed, developmentally down-regulated 9 Ensembl:ENSG00000111859 HGNC:7733 HPRD:11888 MIM:602265 Vega:OTTHUMG00000014255 NEDD9 Bin Zhao, Yue Liu, Oliver He NFNS VRNF WSS WEB: http://www.ncbi.nlm.nih.gov/gene NF1 neurofibromin 1 4763 17q11.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000165 (EC: ISS); GO_0001649 (EC: ISS); GO_0001656 (EC: ISS); GO_0001666 (EC: ISS); GO_0001889 (EC: ISS); GO_0001937 (EC: IMP, PMID: 16648142); GO_0001938 (EC: IEA); GO_0001952 (EC: ISS); GO_0001953 (EC: IEA); GO_0005099 (EC: IDA, PMID: 1568247); GO_0005515 (EC: IPI, PMID: 11356864); GO_0005634 (EC: ISS, PMID: 1550670); GO_0005737 (EC: IBA); GO_0005737 (EC: ISS, PMID: 1550670); GO_0006469 (EC: ISS); GO_0007154 (EC: ISS); GO_0007265 (EC: ISS); GO_0007406 (EC: ISS); GO_0007420 (EC: ISS); GO_0007422 (EC: ISS); GO_0007507 (EC: ISS); GO_0007519 (EC: IEA); GO_0008429 (EC: IDA, PMID: 17187824); GO_0008542 (EC: ISS); GO_0008625 (EC: IEA); GO_0014044 (EC: ISS); GO_0014065 (EC: ISS); GO_0016525 (EC: IEA); GO_0021510 (EC: ISS); GO_0021897 (EC: ISS); GO_0021915 (EC: IEA); GO_0021987 (EC: ISS); GO_0022011 (EC: ISS); GO_0030036 (EC: ISS); GO_0030198 (EC: ISS); GO_0030199 (EC: ISS); GO_0030325 (EC: ISS); GO_0030336 (EC: IMP, PMID: 16648142); GO_0030424 (EC: IDA, PMID: 1550670); GO_0030425 (EC: IDA, PMID: 1550670); GO_0031210 (EC: IDA, PMID: 17187824); GO_0031235 (EC: IBA); GO_0032228 (EC: IEA); GO_0032318 (EC: IMP, PMID: 1570015); GO_0032320 (EC: IDA, PMID: 2121371); GO_0032320 (EC: IMP, PMID: 16648142); GO_0032320 (EC: ISS); GO_0035021 (EC: IEA); GO_0042060 (EC: ISS); GO_0042992 (EC: ISS); GO_0043065 (EC: ISS); GO_0043407 (EC: ISS); GO_0043409 (EC: IMP, PMID: 16648142); GO_0043409 (EC: ISS); GO_0043473 (EC: ISS); GO_0043525 (EC: ISS); GO_0043535 (EC: IMP, PMID: 17404841); GO_0045124 (EC: ISS); GO_0045671 (EC: IEA); GO_0045685 (EC: ISS); GO_0045762 (EC: ISS); GO_0045765 (EC: IMP, PMID: 17404841); GO_0046580 (EC: IBA); GO_0046929 (EC: IEA); GO_0048147 (EC: ISS); GO_0048169 (EC: IEA); GO_0048485 (EC: ISS); GO_0048593 (EC: ISS); GO_0048712 (EC: IEA); GO_0048715 (EC: ISS); GO_0048745 (EC: ISS); GO_0048844 (EC: ISS); GO_0048853 (EC: ISS); GO_0050890 (EC: IMP, PMID: 17299016); GO_1902043 (EC: IEA); GO_2001241 (EC: IEA) PMID: 1302608; 1329097; 1339276; 1457041; 1550670; 1568247; 1570015; 1662505; 1715669; 1719426; 1745350; 1757093; 1783401; 1923522; 1937470; 2114220; 2116237; 2121370; 2121371; 2125369; 2134734; 2491776; 7519874; 7570581; 7633431; 7633452; 7649559; 7686513; 7774960; 7874161; 7903661; 7904209; 7959746; 7981679; 7981724; 8069310; 8081387; 8176268; 8317503; 8417346; 8544190; 8602361; 8619474; 8628317; 8664912; 8807336; 8825042; 8825634; 8834249; 8836031; 8931693; 9002664; 9003501; 9101300; 9110174; 9150739; 9298829; 9300663; 9529361; 9639526; 9668168; 9706718; 10220149; 10336779; 10553997; 10607834; 10625171; 10712197; 10721668; 10862698; 11140831; 11258625; 11356864; 11704931; 11727199; 11727265; 11735023; 11748857; 11751683; 11754043; 11857752; 11896214; 11896613; 11934389; 12073021; 12077339; 12095621; 12152785; 12191989; 12199909; 12368469; 12387455; 12438263; 12477932; 12483293; 12522551; 12552569; 12566521; 12660952; 12707950; 12730209; 12746402; 12807981; 12872266; 12963615; 13679444; 13680360; 14647436; 14722914; 14988005; 15096131; 15146197; 15146469; 15233998; 15302935; 15342556; 15371411; 15389774; 15520408; 15523626; 15523642; 15583390; 15627836; 15735964; 15767669; 15944227; 15988004; 15999204; 16005615; 16081245; 16083285; 16116616; 16138909; 16169856; 16199547; 16344560; 16374483; 16380919; 16405917; 16467218; 16470740; 16479075; 16565220; 16644864; 16648142; 16741618; 16773574; 16813595; 16830335; 16835260; 16835897; 16908010; 16914719; 16944271; 16944272; 17036045; 17053831; 17096025; 17102080; 17160901; 17187824; 17200120; 17216419; 17295913; 17299016; 17353900; 17404841; 17426081; 17514731; 17563086; 17581973; 17668375; 17726231; 17876295; 17880527; 17914445; 17960768; 17999360; 18021924; 18055911; 18086893; 18172006; 18183042; 18212816; 18214791; 18215124; 18218617; 18316778; 18331998; 18407053; 18484666; 18485440; 18503770; 18511569; 18546366; 18592002; 18802710; 18948576; 19041782; 19048115; 19061981; 19120036; 19142971; 19144660; 19215943; 19220708; 19221814; 19238080; 19291764; 19292874; 19351817; 19417008; 19449407; 19601812; 19650418; 19718661; 19773259; 19845691; 19913121; 19940123; 20002172; 20006588; 20015894; 20052761; 20082856; 20124472; 20129251; 20160012; 20160346; 20164853; 20301288; 20358387; 20379614; 20422842; 20428205; 20435627; 20442305; 20503322; 20505189; 20513137; 20543202; 20571392; 20587590; 20602485; 20624961; 20628086; 20655465; 20680410; 20687928; 20725927; 20927530; 21048031; 21089070; 21139048; 21142935; 21157378; 21199919; 21236316; 21244408; 21278392; 21280148; 21283084; 21337692; 21365283; 21478499; 21551249; 21674567; 21728811; 21732117; 21782795; 21890473; 21903422; 21931722; 21963094; 22015770; 22096509; 22105171; 22108604; 22125493; 22190464; 22207399; 22240541; 22241097; 22250039; 22293200; 22294457; 22354384; 22399775; 22412049; 22488919; 22573716; 22581253; 22585738; 22586326; 22700876; 22751498; 22807134; 22837079; 22925204; 22945628; 22962301; 22965642; 22965773; 23000965; 23010473; 23047742; 23077663; 23082153; 23135915; 23145129; 23165953; 23171796; 23222849; 23244495; 23288408; 23292448; 23312374; 23335975; 23437333; 23455922; 23460398; 23481210; 23528211; 23583712; 23624750; 23668869; 23906300; 23947441; 24249802; 24250222; 24255178 neurofibromin 1 Ensembl:ENSG00000196712 HGNC:7765 HPRD:01203 MIM:613113 Vega:OTTHUMG00000132871 NF1 Bin Zhao, Yue Liu, Oliver He NRF2 WEB: http://www.ncbi.nlm.nih.gov/gene NFE2L2 nuclear factor, erythroid 2-like 2 4780 2q31 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0000785 (EC: IEA); GO_0001102 (EC: IPI); GO_0003677 (EC: IDA, PMID: 18554677); GO_0003700 (EC: IEA); GO_0005515 (EC: IPI, PMID: 16888629); GO_0005634 (EC: IDA); GO_0005737 (EC: IDA); GO_0005813 (EC: IDA); GO_0005829 (EC: IDA); GO_0005886 (EC: IDA); GO_0006366 (EC: TAS, PMID: 7937919); GO_0010499 (EC: IDA, PMID: 19424503); GO_0016567 (EC: IDA, PMID: 15983046); GO_0019904 (EC: IPI, PMID: 11256947); GO_0030194 (EC: IEA); GO_0030968 (EC: IEA); GO_0036003 (EC: IMP); GO_0043161 (EC: IDA, PMID: 15983046); GO_0043565 (EC: IEA); GO_0045944 (EC: IMP, PMID: 18202225); GO_0045995 (EC: IEA); GO_0070301 (EC: IMP); GO_0071356 (EC: IMP, PMID: 18202225); GO_0071499 (EC: IMP); GO_1902176 (EC: IMP); GO_2000121 (EC: IEA); GO_2000352 (EC: IMP); GO_2000379 (EC: IEA) PMID: 7868116; 7937919; 9150357; 9872330; 9887101; 10419538; 10510468; 10747902; 10930400; 11013233; 11035812; 11256947; 11274184; 11439354; 11683914; 11909699; 12020345; 12084617; 12084707; 12145307; 12198130; 12360409; 12370194; 12435735; 12441344; 12446695; 12477932; 12490281; 12506115; 12556532; 12805554; 12947090; 14517290; 14517554; 14529549; 14565864; 14585973; 14612418; 14985350; 15020583; 15282312; 15358217; 15367669; 15379550; 15475350; 15489334; 15525690; 15572695; 15601839; 15734732; 15870285; 15901726; 15917227; 15917255; 15923610; 15944151; 15964514; 15983046; 15985429; 16000310; 16006525; 16038408; 16092930; 16123320; 16137655; 16177082; 16220540; 16308312; 16314513; 16325767; 16339837; 16344560; 16478829; 16507366; 16545679; 16551616; 16551619; 16716189; 16790425; 16790436; 16857669; 16888629; 16923960; 16950787; 16951152; 17020408; 17065227; 17077087; 17109620; 17143558; 17145701; 17234762; 17259171; 17384144; 17462537; 17562481; 17603223; 17606720; 17609210; 17636022; 17673673; 17726138; 17822364; 17822677; 17875642; 17875699; 17925401; 17982693; 18029348; 18036733; 18038766; 18049112; 18074351; 18097597; 18156441; 18162601; 18172853; 18202225; 18238777; 18240569; 18241676; 18261463; 18316592; 18353146; 18358244; 18372916; 18387606; 18404535; 18413364; 18417180; 18424257; 18434303; 18444152; 18467642; 18537816; 18554677; 18556627; 18566336; 18566994; 18572023; 18585411; 18613373; 18613447; 18622263; 18692501; 18756969; 18757741; 18802114; 18813798; 18829555; 18838122; 18846238; 18981090; 18981988; 19138946; 19158945; 19182219; 19254160; 19272177; 19273602; 19321346; 19345732; 19417020; 19424503; 19478192; 19484125; 19489739; 19538980; 19558496; 19560419; 19573594; 19575798; 19576171; 19608619; 19614772; 19618868; 19643729; 19668370; 19669099; 19671143; 19706542; 19715681; 19720220; 19720622; 19723058; 19751820; 19808663; 19821532; 19822148; 19844581; 19844776; 19889935; 19901266; 19920073; 19934254; 19948975; 19967722; 20011043; 20026169; 20027226; 20053997; 20061377; 20062840; 20064547; 20064636; 20068043; 20089859; 20103708; 20118824; 20142043; 20175229; 20175230; 20175231; 20175232; 20185790; 20196834; 20211142; 20216230; 20229611; 20232342; 20309604; 20347035; 20368435; 20378532; 20395535; 20418481; 20421418; 20421815; 20427290; 20428777; 20440267; 20446765; 20446773; 20446774; 20452971; 20452972; 20463144; 20484052; 20486933; 20507872; 20511222; 20516531; 20534738; 20534903; 20595649; 20599909; 20608163; 20623181; 20644561; 20647061; 20655719; 20664557; 20673799; 20681784; 20682644; 20707922; 20718723; 20805158; 20805228; 20806931; 20864537; 20887713; 20932318; 20956535; 21051083; 21062981; 21107315; 21127061; 21144518; 21172416; 21196497; 21205897; 21211285; 21211512; 21212410; 21216956; 21228930; 21248763; 21249230; 21251164; 21262351; 21270272; 21277289; 21278237; 21320471; 21357422; 21367536; 21382013; 21383067; 21402726; 21412259; 21422597; 21443946; 21482715; 21487034; 21489257; 21514635; 21524888; 21596795; 21622902; 21638050; 21651857; 21670314; 21676886; 21693764; 21725920; 21734707; 21747966; 21756955; 21799005; 21812759; 21816220; 21842204; 21861350; 21868703; 21875324; 21883218; 21897267; 21906983; 21926171; 21943684; 21949655; 21964605; 21969819; 21988832; 21990354; 22001310; 22005287; 22005302; 22010800; 22016591; 22033923; 22042007; 22048642; 22051934; 22078454; 22089114; 22095074; 22120303; 22125611; 22130023; 22142473; 22188542; 22201269; 22207702; 22213475; 22215675; 22227268; 22245129; 22272327; 22275372; 22279539; 22302998; 22310733; 22314914; 22331464; 22364041; 22370642; 22378150; 22387177; 22445099; 22448038; 22459801; 22460831; 22492997; 22493435; 22513881; 22528837; 22547061; 22558124; 22575091; 22593043; 22594577; 22609006; 22614957; 22645602; 22648520; 22668754; 22672594; 22684020; 22691366; 22693272; 22703534; 22716961; 22749810; 22751928; 22767273; 22791762; 22793650; 22798149; 22804935; 22806321; 22836768; 22851183; 22872865; 22874821; 22901367; 22901690; 22940790; 22942279; 22943825; 22951256; 22964297; 22964583; 22964642; 23023193; 23043106; 23045018; 23046979; 23052169; 23056183; 23056222; 23056578; 23061798; 23066931; 23076395; 23077289; 23089668; 23108405; 23117207; 23165982; 23176750; 23188707; 23244425; 23247010; 23255485; 23259779; 23266269; 23275004; 23276910; 23281314; 23284002; 23305850; 23314856; 23353771; 23365135; 23382044; 23390006; 23403272; 23404377; 23448276; 23454680; 23485615; 23496811; 23499316; 23526214; 23535360; 23536959; 23543742; 23545629; 23557336; 23558695; 23559007; 23563091; 23572560; 23580430; 23583297; 23612120; 23614276; 23622008; 23637463; 23645672; 23648389; 23650051; 23658110; 23661758; 23667609; 23673813; 23686862; 23689140; 23697596; 23699174; 23708697; 23718983; 23722832; 23727018; 23734777; 23766517; 23788642; 23793039; 23857252; 23857982; 23880293; 23887691; 23921124; 23930677; 23933386; 23936010; 23937621; 23938463; 23954767; 23986495; 24011591; 24015256; 24030461; 24035498; 24053646; 24055888; 24059022; 24130096; 24140708; 24211276; 24298019; 24311782; 24323028; 24512214 nuclear factor, erythroid 2-like 2 Ensembl:ENSG00000116044 HGNC:7782 HPRD:02732 MIM:600492 Vega:OTTHUMG00000133620 NFE2L2 Bin Zhao, Yue Liu, Oliver He EBP-1 KBF1 NF-kB1 NF-kappa-B NF-kappaB NFKB-p105 NFKB-p50 NFkappaB p105 p50 WEB: http://www.ncbi.nlm.nih.gov/gene NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 4790 4q24 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0000122 (EC: IC, PMID: 16938301); GO_0000122 (EC: IMP, PMID: 19881551); GO_0000975 (EC: IDA, PMID: 17426251); GO_0000976 (EC: IDA, PMID: 18718911); GO_0001071 (EC: IDA, PMID: 17426251); GO_0001818 (EC: IEA); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0003690 (EC: IEA); GO_0003700 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10023675); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005739 (EC: IDA); GO_0005829 (EC: TAS); GO_0006366 (EC: TAS, PMID: 1992489); GO_0006915 (EC: IEA); GO_0006954 (EC: TAS, PMID: 1992489); GO_0006979 (EC: IEA); GO_0008134 (EC: IDA, PMID: 18270204); GO_0009617 (EC: IEA); GO_0010744 (EC: IC, PMID: 16938301); GO_0010884 (EC: IC, PMID: 16938301); GO_0010956 (EC: IDA, PMID: 15243130); GO_0010957 (EC: IC, PMID: 15243130); GO_0031072 (EC: IEA); GO_0031293 (EC: TAS); GO_0032269 (EC: IC, PMID: 16938301); GO_0032375 (EC: IC, PMID: 16938301); GO_0032481 (EC: TAS); GO_0033256 (EC: TAS, PMID: 16938301); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042803 (EC: IEA); GO_0043066 (EC: TAS, PMID: 10811897); GO_0044212 (EC: IDA, PMID: 16938301); GO_0045083 (EC: IEA); GO_0045087 (EC: TAS); GO_0045893 (EC: IDA, PMID: 17426251); GO_0045893 (EC: IMP); GO_0045893 (EC: NAS, PMID: 8096091); GO_0045944 (EC: IEA); GO_0046688 (EC: IEA); GO_0048011 (EC: TAS); GO_0050728 (EC: IEA); GO_0050852 (EC: TAS); GO_0051092 (EC: TAS); GO_0071260 (EC: IEP, PMID: 19593445); GO_0071347 (EC: IEP, PMID: 12958148); GO_0090263 (EC: IMP); GO_1900127 (EC: IDA, PMID: 17324121) PMID: 1505523; 1508666; 1518839; 1527859; 1583734; 1612589; 1992489; 2017258; 2050119; 2108863; 2203531; 2234062; 2497520; 7494249; 7651415; 7690421; 7692236; 7694229; 7729429; 7739549; 7742037; 7788295; 7800480; 7823959; 7830764; 7838536; 7859743; 7862168; 7891711; 7933095; 7957556; 8087845; 8096091; 8113688; 8139561; 8151786; 8178481; 8196632; 8207793; 8246997; 8255759; 8290595; 8319912; 8423996; 8428580; 8441377; 8550813; 8615004; 8621941; 8627654; 8628291; 8631829; 8642313; 8649779; 8676466; 8692272; 8709193; 8717528; 8724035; 8746784; 8790371; 8798655; 8814265; 8825636; 8834464; 8870842; 8887676; 8997639; 9094628; 9110146; 9135156; 9218802; 9223487; 9235945; 9250404; 9252186; 9278385; 9315679; 9334723; 9368006; 9468519; 9510190; 9525916; 9529257; 9535861; 9556555; 9560267; 9566873; 9566883; 9572494; 9584180; 9621091; 9722548; 9730685; 9738011; 9792375; 9809067; 9837938; 9865693; 9865694; 9895331; 9950430; 9990852; 10023675; 10075655; 10207088; 10225209; 10235509; 10357819; 10362352; 10384093; 10393859; 10400814; 10426996; 10446807; 10469655; 10480634; 10498867; 10562553; 10580107; 10625680; 10635328; 10644332; 10644726; 10646849; 10671224; 10704334; 10723127; 10775602; 10777532; 10799874; 10811897; 10835356; 10847592; 10856288; 10928981; 10931834; 10969074; 10970863; 11020244; 11036073; 11044099; 11094166; 11158290; 11160671; 11241736; 11278695; 11297557; 11299302; 11313474; 11356851; 11385624; 11418662; 11425860; 11468175; 11511100; 11522182; 11526476; 11579140; 11590148; 11607785; 11696595; 11704662; 11739381; 11756416; 11779220; 11819787; 11827962; 11830587; 11830590; 11833470; 11859566; 11880271; 11931769; 11942414; 11943214; 11953428; 11959143; 11970949; 11971907; 11972054; 11976329; 11980335; 11983170; 12019209; 12021045; 12032828; 12032830; 12040437; 12052823; 12057007; 12058256; 12067898; 12077118; 12077347; 12086956; 12089148; 12091382; 12115625; 12122011; 12133438; 12135603; 12145210; 12150710; 12150997; 12166787; 12167619; 12173051; 12181421; 12195699; 12198114; 12203044; 12230568; 12237108; 12244126; 12296854; 12297126; 12297724; 12297725; 12365017; 12388747; 12393603; 12396456; 12406554; 12419805; 12427593; 12428105; 12431991; 12433922; 12444143; 12444202; 12470471; 12471041; 12473373; 12477932; 12482504; 12482669; 12482991; 12485413; 12488445; 12495677; 12496256; 12496485; 12496486; 12538487; 12574335; 12592338; 12594215; 12594338; 12604365; 12606501; 12606947; 12618429; 12620896; 12623850; 12637324; 12644014; 12646168; 12646204; 12667451; 12673201; 12676577; 12693954; 12699902; 12700228; 12709429; 12711606; 12715098; 12727023; 12738634; 12743697; 12743709; 12748173; 12767057; 12771144; 12771929; 12783888; 12820969; 12821113; 12829026; 12832450; 12839942; 12843241; 12855659; 12857898; 12859994; 12860389; 12867284; 12871932; 12872153; 12878172; 12883671; 12884915; 12914931; 12917325; 12919943; 12921778; 12944982; 12947093; 12952968; 12958148; 12958623; 12958678; 12960163; 12963997; 12966099; 12972430; 12972607; 12972622; 12973300; 13679070; 13680285; 14530285; 14534291; 14550290; 14558943; 14561767; 14570916; 14572449; 14573617; 14576361; 14578856; 14581467; 14585847; 14593105; 14597672; 14613970; 14624448; 14625285; 14625298; 14645533; 14647412; 14657027; 14662860; 14663476; 14676829; 14678988; 14679201; 14679213; 14684616; 14685242; 14689584; 14690596; 14691449; 14697238; 14715628; 14729568; 14737065; 14739303; 14743216; 14743471; 14744759; 14747545; 14760757; 14769797; 14963043; 14966375; 15013753; 15016307; 15020601; 15039334; 15043934; 15044484; 15047705; 15053878; 15056731; 15063762; 15068390; 15073126; 15073170; 15078930; 15084608; 15087454; 15090542; 15093615; 15102862; 15103018; 15130920; 15137059; 15142381; 15143182; 15147743; 15169888; 15173174; 15175625; 15178248; 15179048; 15184376; 15184390; 15187159; 15188354; 15190178; 15203187; 15208298; 15217951; 15218148; 15226292; 15226448; 15238257; 15241416; 15242768; 15243130; 15251447; 15252018; 15254772; 15257133; 15258149; 15276183; 15280372; 15280531; 15297971; 15310755; 15314185; 15315758; 15319438; 15327770; 15337758; 15345718; 15351720; 15358208; 15364309; 15373762; 15383283; 15383523; 15389633; 15457532; 15459191; 15466412; 15467918; 15469820; 15471861; 15477018; 15485865; 15486815; 15489334; 15494311; 15496460; 15498932; 15501771; 15514680; 15521376; 15522218; 15528271; 15532722; 15535802; 15543947; 15545823; 15550679; 15561713; 15563086; 15564333; 15569630; 15569997; 15578154; 15591054; 15591119; 15597152; 15601829; 15610077; 15618021; 15618216; 15623625; 15627743; 15638726; 15640523; 15642694; 15642734; 15647756; 15650392; 15650393; 15650394; 15653692; 15657065; 15661045; 15670752; 15677444; 15678501; 15687488; 15688415; 15694363; 15701651; 15713218; 15713234; 15718492; 15722350; 15722553; 15725353; 15725474; 15727562; 15735699; 15735750; 15743789; 15746262; 15746428; 15757899; 15767394; 15780175; 15799966; 15802604; 15809302; 15811852; 15817944; 15827086; 15829968; 15830705; 15869598; 15870177; 15876358; 15894171; 15905616; 15905705; 15920558; 15922296; 15940251; 15941782; 15944151; 15951441; 15955209; 15964798; 15964800; 15972330; 15972853; 15979574; 15979856; 15982633; 15991283; 16001969; 16004996; 16005433; 16029077; 16039990; 16039994; 16044154; 16046401; 16046415; 16079148; 16081580; 16082226; 16087150; 16088959; 16105840; 16108830; 16116232; 16123212; 16142329; 16142871; 16155293; 16167336; 16199137; 16203728; 16204234; 16206345; 16207722; 16210649; 16212965; 16219794; 16223733; 16234240; 16236134; 16237100; 16243842; 16258173; 16260783; 16266460; 16270046; 16280329; 16285952; 16288847; 16289658; 16291755; 16299251; 16299518; 16303162; 16305395; 16306043; 16306601; 16308565; 16313306; 16318585; 16319921; 16319923; 16325763; 16341093; 16364464; 16380507; 16387424; 16397577; 16397579; 16407234; 16408727; 16410801; 16410802; 16410803; 16418290; 16424045; 16429131; 16429138; 16436380; 16439988; 16441485; 16452479; 16455661; 16465659; 16476711; 16485028; 16490783; 16491128; 16497967; 16498458; 16504042; 16513645; 16514159; 16519794; 16519819; 16528384; 16543241; 16554660; 16569657; 16571778; 16601113; 16616657; 16624823; 16630341; 16631615; 16635909; 16644866; 16651450; 16651613; 16678126; 16680372; 16684768; 16690938; 16697675; 16709572; 16722389; 16728660; 16740634; 16740744; 16751281; 16756716; 16757480; 16769768; 16771709; 16774937; 16778171; 16799643; 16804398; 16804400; 16816390; 16820889; 16822500; 16835229; 16840782; 16840786; 16857678; 16879221; 16891304; 16893890; 16906147; 16907704; 16912315; 16914552; 16919057; 16919536; 16926151; 16927804; 16928771; 16938301; 16951147; 16973832; 16979873; 16979925; 16980310; 16984419; 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23843455; 23861985; 23869088; 23880092; 23887394; 23900863; 23908590; 23911423; 23921373; 23935876; 23942618; 23954632; 23969028; 23982206; 24008839; 24027435; 24035972; 24041570; 24045046; 24048682; 24054986; 24065232; 24067962; 24077340; 24097561; 24098051; 24099783; 24109220; 24109241; 24113181; 24145029; 24145431; 24152244; 24175631; 24258200; 24270572; 24282904; 24297735; 24316229; 24321067; 24352326; 24367071; 24368180; 24436266; 24510559 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Ensembl:ENSG00000109320 HGNC:7794 HPRD:01238 MIM:164011 Vega:OTTHUMG00000161080 NFKB1 Bin Zhao, Yue Liu, Oliver He Beta-NGF HSAN5 NGFB WEB: http://www.ncbi.nlm.nih.gov/gene NGF nerve growth factor (beta polypeptide) 4803 1p13.1 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000186 (EC: TAS); GO_0005057 (EC: IEA); GO_0005163 (EC: IPI, PMID: 14985763); GO_0005576 (EC: TAS); GO_0005615 (EC: IEA); GO_0005768 (EC: TAS); GO_0005796 (EC: TAS); GO_0006954 (EC: IEA); GO_0007169 (EC: TAS); GO_0007202 (EC: TAS); GO_0007264 (EC: TAS); GO_0007265 (EC: TAS); GO_0007422 (EC: IEA); GO_0007613 (EC: IEA); GO_0008083 (EC: IEA); GO_0008344 (EC: IEA); GO_0008625 (EC: IDA, PMID: 14985763); GO_0009314 (EC: IEA); GO_0009612 (EC: IEA); GO_0010193 (EC: IEA); GO_0010628 (EC: IMP, PMID: 16153003); GO_0019233 (EC: IEA); GO_0031954 (EC: IEA); GO_0032455 (EC: TAS); GO_0032496 (EC: IEA); GO_0035094 (EC: IEA); GO_0042493 (EC: IEA); GO_0043065 (EC: TAS); GO_0043066 (EC: TAS); GO_0043281 (EC: TAS); GO_0043434 (EC: IEA); GO_0043524 (EC: IEA); GO_0045666 (EC: IEA); GO_0045773 (EC: IEA); GO_0045786 (EC: TAS); GO_0046928 (EC: IEA); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0048812 (EC: IDA, PMID: 17724343); GO_0050770 (EC: TAS); GO_0050772 (EC: TAS); GO_0051091 (EC: IEA); GO_0051384 (EC: IEA); GO_0051388 (EC: IEA); GO_0051402 (EC: IEA); GO_0051602 (EC: IEA); GO_0097190 (EC: TAS); GO_0097192 (EC: IEA); GO_2000648 (EC: IEA); GO_2000675 (EC: IEA) PMID: 1383421; 1692298; 2025430; 2374737; 2906326; 3871525; 6327169; 6330750; 6648531; 6688123; 7789166; 7806500; 8178451; 8615794; 8808283; 8895847; 9069267; 9182757; 9252186; 9351801; 9575168; 9915784; 10022904; 10322959; 10391209; 10490030; 10629055; 10681572; 10708862; 10712923; 10764727; 10806167; 11157096; 11244088; 11278287; 11487608; 11520933; 11729324; 11738045; 11830582; 11877300; 11935372; 12205295; 12371150; 12376548; 12397373; 12453472; 12477932; 12531456; 12676754; 12676795; 12787561; 12787574; 12900521; 12918708; 12925217; 14587217; 14708938; 14960584; 14970904; 14976160; 14985763; 15128850; 15131306; 15258592; 15361847; 15489334; 15523689; 15544837; 15681836; 15710408; 15721744; 15829579; 16079148; 16153003; 16215275; 16284401; 16313302; 16319926; 16546643; 16630834; 16710414; 16741963; 16786155; 16832412; 16839849; 16919030; 16939974; 16997282; 17081983; 17192954; 17335080; 17487982; 17638883; 17673289; 17703412; 17724343; 17850422; 17854142; 17881264; 17893397; 17905097; 17992191; 18068123; 18179783; 18191449; 18199526; 18203754; 18221326; 18280641; 18300262; 18305571; 18349121; 18420729; 18438945; 18596692; 18635195; 18727839; 18763222; 18780967; 18810245; 18830907; 18922682; 18922683; 19023688; 19038326; 19038341; 19054925; 19063739; 19076929; 19086053; 19120874; 19169037; 19177265; 19183217; 19221293; 19258923; 19264868; 19399531; 19403065; 19475530; 19490633; 19560628; 19598235; 19626992; 19639490; 19649262; 19651702; 19668232; 19695094; 19758188; 19844736; 19874574; 19934806; 19945432; 19950533; 19957796; 19958603; 20119692; 20219210; 20233324; 20360245; 20375017; 20398908; 20503287; 20518854; 20542022; 20680101; 20854189; 20863878; 20881126; 20889312; 20923384; 20978020; 21047631; 21085492; 21153361; 21217078; 21294249; 21321391; 21358750; 21378097; 21387003; 21397006; 21429417; 21596795; 21621608; 21673280; 21693611; 21768088; 21826717; 21893340; 22036954; 22040304; 22105621; 22192858; 22251933; 22272270; 22301435; 22330829; 22411587; 22454143; 22517242; 22537619; 22625872; 22703891; 22731611; 22804708; 22932111; 22948388; 22948508; 22954667; 23028581; 23034254; 23086522; 23091165; 23095849; 23128606; 23234779; 23535911; 23542336; 23561736; 23574818; 23608378; 23637956; 23778138; 23869086; 23989259 nerve growth factor (beta polypeptide) Ensembl:ENSG00000134259 HGNC:7808 HPRD:08874 MIM:162030 Vega:OTTHUMG00000011880 NGF Bin Zhao, Yue Liu, Oliver He CD271 Gp80-LNGFR TNFRSF16 p75(NTR) p75NTR WEB: http://www.ncbi.nlm.nih.gov/gene NGFR nerve growth factor receptor 4804 17q21-q22 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0004871 (EC: TAS, PMID: 3022937); GO_0004872 (EC: TAS, PMID: 3022937); GO_0004888 (EC: TAS, PMID: 1846035); GO_0005035 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11756426); GO_0005576 (EC: TAS); GO_0005654 (EC: TAS); GO_0005768 (EC: TAS); GO_0005829 (EC: TAS); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 3022937); GO_0006886 (EC: ISS); GO_0007411 (EC: IEA); GO_0007417 (EC: IEA); GO_0008625 (EC: IEA); GO_0009986 (EC: ISS); GO_0010468 (EC: IEA); GO_0016048 (EC: IEA); GO_0017137 (EC: ISS); GO_0021675 (EC: IEA); GO_0031069 (EC: IEA); GO_0031293 (EC: TAS); GO_0031625 (EC: IPI, PMID: 11279055); GO_0040037 (EC: IEA); GO_0042488 (EC: IEA); GO_0042593 (EC: ISS); GO_0043065 (EC: TAS); GO_0043066 (EC: TAS); GO_0043281 (EC: TAS); GO_0045786 (EC: TAS); GO_0048011 (EC: TAS); GO_0048146 (EC: IEA); GO_0048406 (EC: IEA); GO_0050770 (EC: TAS); GO_0050771 (EC: TAS); GO_0050772 (EC: TAS); GO_0051799 (EC: IEA); GO_0097190 (EC: TAS); GO_2001235 (EC: IEA); GO_2001273 (EC: ISS) PMID: 1281863; 1316918; 1324502; 1846035; 2850481; 2989274; 3006050; 3008331; 3020711; 3022937; 7541035; 7541633; 7903404; 8407983; 8614797; 8627329; 8889548; 9252186; 9368064; 9575168; 9626059; 9665396; 9867838; 9915784; 9927421; 10022904; 10485890; 10514511; 10544233; 10545116; 10595511; 10764727; 10985348; 11150334; 11201742; 11244088; 11278287; 11279055; 11487608; 11729324; 11756426; 11756498; 11818506; 11830582; 11927634; 12011108; 12034707; 12107411; 12163480; 12371150; 12376548; 12414813; 12422217; 12426574; 12460612; 12477932; 12604596; 12672029; 12676795; 12682012; 12692556; 12716928; 12768436; 12787561; 12789270; 12821676; 12821936; 12843241; 12913006; 12951563; 12963025; 14593116; 14689592; 14960584; 14966521; 14985763; 15015775; 15128850; 15131306; 15165637; 15258592; 15274039; 15310753; 15337528; 15378608; 15489334; 15523689; 15681836; 15694321; 15701642; 15721744; 15784962; 15953414; 16099913; 16113645; 16215275; 16215672; 16344560; 16460673; 16498402; 16555252; 16586073; 16630834; 16704535; 16826429; 16893414; 16951226; 16997282; 17110619; 17196528; 17287525; 17335080; 17349981; 17355907; 17357149; 17492429; 17510309; 17531524; 17582777; 17603629; 17619016; 17696644; 17703412; 17850422; 17947706; 17971243; 17986144; 18029348; 18036543; 18081157; 18196575; 18203754; 18221326; 18305571; 18319596; 18394312; 18428117; 18462868; 18470533; 18477014; 18540978; 18566344; 18780967; 19041213; 19066726; 19072833; 19086053; 19131967; 19169037; 19177265; 19225519; 19240061; 19258923; 19301169; 19386345; 19490633; 19598235; 19615036; 19758188; 19918800; 19945432; 20022966; 20219210; 20237496; 20351714; 20503287; 20530577; 20549701; 20596026; 20659559; 20680101; 20854189; 20943663; 21097678; 21123453; 21142793; 21151024; 21178583; 21307265; 21343882; 21393506; 21397006; 21418516; 21503896; 21807134; 21814043; 21851375; 21900206; 21938001; 21982860; 22040987; 22068036; 22138126; 22161836; 22170235; 22207443; 22236693; 22343487; 22419851; 22454143; 22558167; 22566094; 22610502; 22635104; 22706116; 22710983; 22932111; 22954667; 23017601; 23065828; 23105112; 23105113; 23260665; 23268325; 23300742; 23371454; 23471969; 23489213; 23535732; 23576602; 23598407; 23598854; 23600400; 23616554; 23626764; 23642664; 23820422; 23831066; 24047966 nerve growth factor receptor Ensembl:ENSG00000064300 HGNC:7809 HPRD:01197 MIM:162010 Vega:OTTHUMG00000161495 NGFR Bin Zhao, Yue Liu, Oliver He IHPS1 N-NOS NC-NOS NOS bNOS nNOS WEB: http://www.ncbi.nlm.nih.gov/gene NOS1 nitric oxide synthase 1 (neuronal) 4842 12q24.22 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0001666 (EC: IEP, PMID: 16276418); GO_0001917 (EC: ISS, PMID: 17027776); GO_0003958 (EC: IBA); GO_0004517 (EC: IBA); GO_0004517 (EC: ISS); GO_0005506 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11149895); GO_0005516 (EC: IEA); GO_0005737 (EC: TAS, PMID: 17892502); GO_0005829 (EC: TAS); GO_0005856 (EC: ISS, PMID: 7545544); GO_0006527 (EC: IC, PMID: 7545544); GO_0006809 (EC: IBA); GO_0006809 (EC: ISS, PMID: 7545544); GO_0006941 (EC: IEA); GO_0007263 (EC: IBA); GO_0007520 (EC: TAS, PMID: 7545544); GO_0007596 (EC: TAS); GO_0009408 (EC: IDA, PMID: 18048451); GO_0010181 (EC: ISS); GO_0010523 (EC: TAS, PMID: 17568574); GO_0016491 (EC: IBA); GO_0016529 (EC: IDA, PMID: 9892689); GO_0017080 (EC: ISS); GO_0018119 (EC: ISS); GO_0020037 (EC: ISS); GO_0031284 (EC: IBA); GO_0033555 (EC: IMP, PMID: 18391107); GO_0034617 (EC: NAS, PMID: 7488039); GO_0034618 (EC: TAS, PMID: 17029414); GO_0035066 (EC: IEA); GO_0042136 (EC: TAS, PMID: 7545544); GO_0042383 (EC: IDA, PMID: 7545544); GO_0042738 (EC: IEA); GO_0043197 (EC: IEA); GO_0043234 (EC: ISS); GO_0043267 (EC: IEA); GO_0044325 (EC: ISS); GO_0045202 (EC: IEA); GO_0045776 (EC: IBA); GO_0045909 (EC: IDA, PMID: 18048451); GO_0045909 (EC: IMP, PMID: 18391107); GO_0045944 (EC: IEA); GO_0046870 (EC: ISS); GO_0048471 (EC: ISS, PMID: 17027776); GO_0050660 (EC: ISS); GO_0050661 (EC: ISS); GO_0051346 (EC: IEA); GO_0051612 (EC: IEA); GO_0051701 (EC: TAS); GO_0055117 (EC: TAS, PMID: 9892689); GO_0071363 (EC: IEA); GO_0090382 (EC: TAS); GO_0097110 (EC: ISS); GO_1902307 (EC: ISS) PMID: 1375933; 1379716; 1385308; 7488039; 7515942; 7521167; 7528745; 7545544; 7558036; 7561697; 7678401; 7682706; 7685260; 8581564; 8625413; 8864115; 8879752; 8922396; 8943206; 9111048; 9353265; 9412493; 9459447; 9791007; 9808772; 9837926; 9870939; 9880522; 9892689; 10068656; 10187848; 10203575; 10221915; 10400690; 10443886; 10488080; 10518591; 10681501; 10751385; 10824095; 10874031; 11043403; 11052978; 11086993; 11112111; 11149895; 11284722; 11404282; 11511520; 11525805; 11546971; 11590170; 11591728; 11668616; 11747091; 11786430; 11849436; 11849441; 11867766; 11890749; 11960979; 12081486; 12081996; 12140778; 12184796; 12210288; 12237228; 12403769; 12421162; 12445599; 12477932; 12485841; 12490535; 12531780; 12572877; 12630910; 12646269; 12686399; 12715886; 12759556; 12777376; 12782337; 12787407; 12802542; 12816735; 12908999; 12911502; 12947326; 14602725; 14615895; 14623375; 14711010; 14752097; 14757827; 14759629; 14760158; 14980078; 15033959; 15044250; 15075442; 15080837; 15088155; 15094474; 15105416; 15119548; 15161750; 15167446; 15180967; 15191553; 15194886; 15242984; 15251453; 15287858; 15466472; 15548660; 15699372; 15765269; 15856945; 16191396; 16229016; 16238787; 16276418; 16380905; 16389274; 16413742; 16569214; 16690617; 16780147; 16848803; 16950998; 17027776; 17029414; 17161399; 17161551; 17174475; 17328085; 17351066; 17351927; 17359361; 17360663; 17365914; 17418914; 17448763; 17459909; 17466601; 17492662; 17536218; 17568574; 17579350; 17601350; 17660395; 17690329; 17703412; 17892502; 17924542; 17970747; 18024942; 18042235; 18048451; 18058820; 18086269; 18257968; 18391107; 18465682; 18541744; 18544180; 18563708; 18591664; 18606955; 18614941; 18671896; 18675932; 18720901; 18784277; 18821565; 18953332; 18971208; 18977241; 19086053; 19087148; 19089323; 19103196; 19124687; 19161160; 19247692; 19258923; 19326438; 19328558; 19371282; 19372141; 19415232; 19423521; 19423540; 19433760; 19457105; 19505917; 19513863; 19552920; 19603529; 19642705; 19657898; 19687346; 19711100; 19726320; 19726747; 19805695; 19844207; 19851341; 19913121; 19948738; 19997858; 20016223; 20028935; 20043967; 20052609; 20056178; 20060328; 20186396; 20232214; 20379614; 20385275; 20395963; 20406964; 20421643; 20435320; 20438785; 20447567; 20470850; 20503287; 20537599; 20547234; 20581851; 20589495; 20605417; 20609134; 20628086; 20645313; 20705916; 20729196; 20818978; 20888049; 20921115; 21039601; 21041608; 21052031; 21056687; 21098972; 21119059; 21204701; 21281558; 21403107; 21413022; 21467233; 21505843; 21520349; 21545853; 21577011; 21612410; 21613201; 21620982; 21642500; 21679499; 21722677; 21724667; 21847584; 21922604; 22003386; 22008325; 22095614; 22227051; 22374200; 22448456; 22457368; 22486744; 22560594; 22579290; 22589245; 22613021; 22797309; 22875507; 22885173; 22937753; 23062293; 23109339; 23159936; 23289611; 23406356; 23541953; 23567464; 23572278; 23770231; 23826716; 24063785; 24114042; 24235139 nitric oxide synthase 1 (neuronal) Ensembl:ENSG00000089250 HGNC:7872 HPRD:01226 MIM:163731 Vega:OTTHUMG00000137376 NOS1 Bin Zhao, Yue Liu, Oliver He HEP-NOS INOS NOS NOS2A WEB: http://www.ncbi.nlm.nih.gov/gene NOS2 nitric oxide synthase 2, inducible 4843 17q11.2-q12 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0001666 (EC: IEA); GO_0001912 (EC: TAS, PMID: 10450191); GO_0002227 (EC: NAS, PMID: 18390757); GO_0003958 (EC: IBA); GO_0004517 (EC: IDA, PMID: 7504305); GO_0005102 (EC: IPI); GO_0005506 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12855682); GO_0005516 (EC: IEA); GO_0005622 (EC: IDA, PMID: 7544003); GO_0005634 (EC: ISS); GO_0005737 (EC: IDA, PMID: 12085352); GO_0005777 (EC: IDA, PMID: 12085352); GO_0005829 (EC: IMP, PMID: 7504305); GO_0005829 (EC: TAS); GO_0006527 (EC: IDA, PMID: 7504305); GO_0006801 (EC: ISS); GO_0006809 (EC: IDA, PMID: 7504305); GO_0006954 (EC: IBA); GO_0007263 (EC: IBA); GO_0007596 (EC: TAS); GO_0009617 (EC: NAS, PMID: 12085352); GO_0010181 (EC: ISS); GO_0010629 (EC: IGI, PMID: 12085352); GO_0018119 (EC: ISS); GO_0020037 (EC: ISS); GO_0030863 (EC: IEA); GO_0031284 (EC: IBA); GO_0034617 (EC: ISS); GO_0034618 (EC: ISS); GO_0042127 (EC: IEA); GO_0042177 (EC: IEA); GO_0042742 (EC: IMP, PMID: 9284131); GO_0042742 (EC: ISS); GO_0042803 (EC: ISS); GO_0043457 (EC: TAS, PMID: 10450191); GO_0045776 (EC: IBA); GO_0045909 (EC: IBA); GO_0048471 (EC: IEA); GO_0050660 (EC: ISS); GO_0050661 (EC: TAS, PMID: 7504305); GO_0050796 (EC: IMP, PMID: 8383325); GO_0050829 (EC: NAS, PMID: 18390757); GO_0051701 (EC: TAS); GO_0051712 (EC: IMP, PMID: 7544003); GO_0071222 (EC: IEA); GO_0071346 (EC: IEA); GO_0090382 (EC: TAS) PMID: 7504305; 7509810; 7514565; 7522054; 7524082; 7526541; 7528017; 7528106; 7531613; 7531687; 7532248; 7544003; 7544004; 7558036; 7561697; 7682706; 7692964; 8383325; 8645258; 8653828; 8699932; 8760410; 8943206; 9160867; 9239710; 9284131; 9870939; 9916929; 10068656; 10074942; 10203575; 10393859; 10409685; 10443886; 10446807; 10450191; 10842192; 11050162; 11114180; 11294696; 11297817; 11397889; 11422783; 11424980; 11443559; 11457725; 11525805; 11579140; 11692109; 11761338; 11783017; 11849384; 11880293; 11907646; 11956620; 11978184; 11985259; 11985871; 12060397; 12080081; 12081717; 12085352; 12097137; 12117977; 12119468; 12125143; 12135432; 12140750; 12167619; 12174362; 12195390; 12221289; 12223351; 12237122; 12243747; 12296866; 12374680; 12381793; 12399227; 12406306; 12421162; 12431203; 12433515; 12445411; 12445599; 12452003; 12459168; 12462194; 12477932; 12482371; 12486325; 12489192; 12490535; 12508391; 12509623; 12533668; 12552317; 12578118; 12590140; 12598314; 12601489; 12607534; 12631094; 12641410; 12687343; 12690222; 12709136; 12732844; 12736741; 12768436; 12777376; 12788789; 12799216; 12800233; 12816735; 12824008; 12828935; 12855682; 12875991; 12919943; 12937869; 12948935; 12958187; 12960352; 14551604; 14574328; 14614131; 14614209; 14616549; 14623011; 14634838; 14636285; 14638407; 14677189; 14715665; 14740870; 14764920; 14981908; 14985675; 14991947; 15026539; 15044505; 15100320; 15107292; 15112337; 15115662; 15174013; 15180967; 15205363; 15222024; 15222037; 15226517; 15242984; 15259072; 15271950; 15275951; 15284293; 15285794; 15349722; 15482399; 15482484; 15484300; 15492785; 15494775; 15532709; 15583989; 15601772; 15609395; 15617837; 15631944; 15631946; 15642965; 15654505; 15683721; 15695237; 15754329; 15784171; 15838334; 15849807; 15856071; 15856945; 15922861; 15940772; 16020977; 16105645; 16116474; 16126846; 16136006; 16191398; 16195370; 16211247; 16229182; 16243805; 16260491; 16265698; 16282997; 16288199; 16290060; 16311916; 16326029; 16335796; 16352737; 16442500; 16456243; 16464859; 16543247; 16557582; 16569659; 16573167; 16574921; 16634870; 16681724; 16684839; 16703578; 16771679; 16780147; 16813666; 16820946; 16823855; 16848803; 16865710; 16889995; 16919057; 16924421; 16937436; 16950790; 16950998; 17062130; 17062169; 17065568; 17070441; 17070777; 17072962; 17149600; 17159127; 17160951; 17174475; 17177683; 17189532; 17223386; 17233833; 17240318; 17267840; 17272999; 17296902; 17320454; 17322004; 17328085; 17355643; 17404026; 17408468; 17456572; 17475563; 17482959; 17492134; 17492662; 17507652; 17553719; 17600738; 17601350; 17650819; 17657783; 17674321; 17675371; 17687170; 17693978; 17703412; 17709521; 17720813; 17761309; 17804409; 17849424; 17854833; 17855767; 17881462; 17884453; 17908769; 17928287; 17940019; 17953212; 17955236; 17991113; 18024942; 18029351; 18050214; 18070432; 18077487; 18079278; 18091741; 18184270; 18217711; 18254476; 18279675; 18281043; 18287876; 18301246; 18313411; 18349295; 18390757; 18398039; 18414703; 18459037; 18465682; 18472017; 18474259; 18476605; 18500734; 18502573; 18510611; 18515325; 18563708; 18567618; 18571252; 18579232; 18579559; 18580885; 18585800; 18597705; 18625015; 18648197; 18660489; 18668140; 18675932; 18676680; 18676870; 18714530; 18720901; 18753139; 18753331; 18774388; 18820242; 18828052; 18835789; 18849972; 18923065; 18936436; 18945831; 18955503; 18974840; 18977241; 18977990; 19012493; 19028820; 19038328; 19039588; 19059114; 19064572; 19074427; 19074885; 19086053; 19089323; 19096157; 19103526; 19120907; 19130609; 19131335; 19131662; 19132106; 19135542; 19139419; 19147409; 19153766; 19161160; 19161531; 19168583; 19170196; 19178812; 19184355; 19220629; 19225544; 19238344; 19242068; 19247692; 19258923; 19263529; 19286578; 19291698; 19306295; 19307105; 19309520; 19317804; 19327239; 19334623; 19336370; 19337240; 19358819; 19362296; 19376148; 19381485; 19395279; 19402223; 19403642; 19415311; 19423521; 19423540; 19443702; 19467240; 19479237; 19482272; 19495976; 19497798; 19505917; 19539448; 19540363; 19559392; 19575238; 19614918; 19624767; 19625176; 19635578; 19667218; 19669598; 19692168; 19692623; 19713467; 19723394; 19734575; 19737939; 19741110; 19773451; 19788069; 19797159; 19797925; 19799816; 19828635; 19837302; 19847812; 19859740; 19875457; 19912632; 19913121; 19953876; 19996333; 20015194; 20022949; 20027603; 20028935; 20056178; 20059423; 20060328; 20069397; 20074466; 20086011; 20100830; 20155468; 20177899; 20178365; 20228252; 20232214; 20300066; 20346360; 20374233; 20398908; 20405237; 20406964; 20416077; 20438785; 20438856; 20452482; 20453000; 20459417; 20459687; 20503287; 20518847; 20536507; 20541418; 20542496; 20547234; 20562898; 20565800; 20581851; 20600009; 20600019; 20603037; 20603330; 20619687; 20628086; 20634424; 20644561; 20673868; 20675273; 20711808; 20713430; 20714866; 20811009; 20811626; 20831369; 20850837; 20868689; 20869428; 20871160; 20874490; 20886685; 20888049; 20953189; 20959455; 20978357; 21039601; 21039732; 21052031; 21054877; 21067489; 21073541; 21094287; 21129360; 21158070; 21199876; 21204701; 21333324; 21376344; 21481004; 21506111; 21507301; 21507981; 21533769; 21535025; 21547253; 21549100; 21612325; 21612410; 21630437; 21660141; 21663943; 21690090; 21700708; 21710354; 21716319; 21718007; 21722677; 21729780; 21744319; 21799753; 21803041; 21857382; 21874355; 21883620; 22012771; 22014124; 22055874; 22063737; 22065579; 22086003; 22147556; 22198200; 22205923; 22209000; 22215089; 22234503; 22244784; 22258388; 22329647; 22331023; 22349263; 22363694; 22368302; 22374200; 22409880; 22425195; 22438824; 22451906; 22486744; 22588838; 22613330; 22675938; 22704420; 22711891; 22734893; 22797309; 22862164; 22865486; 22957045; 22992806; 23002365; 23089636; 23128233; 23192595; 23233037; 23239081; 23261943; 23266817; 23338972; 23438482; 23438852; 23452051; 23454417; 23471078; 23496965; 23570607; 23572278; 23599434; 23687977; 23711718; 23764028; 23773706; 23797095; 23812491; 23826716; 23831683; 23935399; 24035972; 24114042; 24177007; 24189859; 24273952 nitric oxide synthase 2, inducible Ensembl:ENSG00000007171 HGNC:7873 HPRD:01225 MIM:163730 Vega:OTTHUMG00000132445 NOS2 Bin Zhao, Yue Liu, Oliver He TAN1 hN1 WEB: http://www.ncbi.nlm.nih.gov/gene NOTCH1 notch 1 4851 9q34.3 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000122 (EC: ISS); GO_0000139 (EC: TAS); GO_0001047 (EC: ISS); GO_0001190 (EC: ISS); GO_0001701 (EC: IEA); GO_0001708 (EC: IEA); GO_0001837 (EC: ISS); GO_0001889 (EC: IEA); GO_0001947 (EC: ISS); GO_0002040 (EC: IEA); GO_0002193 (EC: IDA, PMID: 16510869); GO_0002437 (EC: IEA); GO_0003157 (EC: ISS); GO_0003160 (EC: ISS); GO_0003162 (EC: IEA); GO_0003169 (EC: ISS); GO_0003180 (EC: IMP, PMID: 16025100); GO_0003181 (EC: ISS); GO_0003184 (EC: IMP, PMID: 16025100); GO_0003192 (EC: IMP, PMID: 16025100); GO_0003198 (EC: ISS); GO_0003203 (EC: ISS); GO_0003207 (EC: ISS); GO_0003208 (EC: ISS); GO_0003209 (EC: ISS); GO_0003213 (EC: ISS); GO_0003214 (EC: ISS); GO_0003219 (EC: IEA); GO_0003222 (EC: ISS); GO_0003241 (EC: ISS); GO_0003256 (EC: ISS); GO_0003270 (EC: IEA); GO_0003273 (EC: ISS); GO_0003344 (EC: ISS); GO_0003700 (EC: IEA); GO_0004857 (EC: ISS); GO_0004872 (EC: IEA); GO_0005509 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10713164); GO_0005576 (EC: TAS); GO_0005634 (EC: ISS); GO_0005634 (EC: TAS, PMID: 10713164); GO_0005654 (EC: TAS); GO_0005789 (EC: TAS); GO_0005829 (EC: TAS); GO_0005886 (EC: TAS); GO_0006355 (EC: TAS, PMID: 10713164); GO_0006367 (EC: TAS); GO_0006955 (EC: NAS, PMID: 1831692); GO_0006959 (EC: IEA); GO_0007219 (EC: IMP, PMID: 19682396); GO_0007219 (EC: TAS, PMID: 10713164); GO_0007220 (EC: TAS); GO_0007221 (EC: ISS); GO_0007368 (EC: ISS); GO_0007386 (EC: IEA); GO_0007409 (EC: IEA); GO_0007440 (EC: IEA); GO_0007492 (EC: IEA); GO_0007507 (EC: IMP); GO_0008284 (EC: IDA, PMID: 17849174); GO_0008284 (EC: IMP); GO_0008285 (EC: IDA); GO_0009912 (EC: IEA); GO_0009986 (EC: IEA); GO_0010001 (EC: IEA); GO_0010467 (EC: TAS); GO_0010718 (EC: IMP, PMID: 17984306); GO_0010812 (EC: IDA, PMID: 16501043); GO_0010832 (EC: ISS); GO_0014031 (EC: ISS); GO_0014807 (EC: IEA); GO_0016021 (EC: IEA); GO_0019899 (EC: ISS); GO_0021915 (EC: IEA); GO_0030216 (EC: IEA); GO_0030279 (EC: ISS); GO_0030324 (EC: IEA); GO_0030335 (EC: ISS); GO_0030513 (EC: ISS); GO_0030514 (EC: ISS); GO_0030900 (EC: IEA); GO_0031069 (EC: IEA); GO_0031490 (EC: IEA); GO_0032495 (EC: IEA); GO_0035116 (EC: IEA); GO_0035148 (EC: IMP); GO_0035914 (EC: IEA); GO_0035924 (EC: IDA); GO_0042640 (EC: IEA); GO_0043065 (EC: IEA); GO_0043086 (EC: ISS); GO_0043235 (EC: IDA); GO_0043565 (EC: IEA); GO_0045618 (EC: IEA); GO_0045662 (EC: IMP, PMID: 10713164); GO_0045668 (EC: ISS); GO_0045892 (EC: ISS); GO_0045893 (EC: ISS); GO_0045944 (EC: IDA); GO_0045944 (EC: ISS); GO_0045955 (EC: IEA); GO_0046427 (EC: ISS); GO_0046533 (EC: IEA); GO_0048103 (EC: IEA); GO_0048711 (EC: ISS); GO_0048715 (EC: ISS); GO_0048754 (EC: IEA); GO_0050679 (EC: IEA); GO_0050768 (EC: ISS); GO_0055008 (EC: ISS); GO_0060038 (EC: IEA); GO_0060045 (EC: ISS); GO_0060253 (EC: ISS); GO_0060271 (EC: ISS); GO_0060317 (EC: ISS); GO_0060411 (EC: ISS); GO_0060412 (EC: IMP, PMID: 16025100); GO_0060528 (EC: IEA); GO_0060740 (EC: IEA); GO_0060768 (EC: IEA); GO_0060842 (EC: ISS); GO_0060843 (EC: ISS); GO_0060948 (EC: ISS); GO_0060956 (EC: ISS); GO_0060979 (EC: ISS); GO_0060982 (EC: ISS); GO_0061314 (EC: IMP, PMID: 16025100); GO_0061384 (EC: ISS); GO_0061419 (EC: ISS); GO_0070986 (EC: IEA); GO_0071372 (EC: IDA); GO_0072017 (EC: IEA); GO_0072044 (EC: IEA); GO_0072144 (EC: IEA); GO_0072602 (EC: IEA); GO_0090051 (EC: IDA); GO_0090090 (EC: IEA); GO_0097150 (EC: IEP, PMID: 19682396); GO_1901201 (EC: ISS); GO_1902263 (EC: IEA); GO_2000737 (EC: IMP, PMID: 19682396); GO_2000811 (EC: IMP, PMID: 17984306); GO_2000974 (EC: ISS); GO_2001027 (EC: IDA) PMID: 1764995; 1831692; 7512837; 7698746; 8642313; 8749394; 8755477; 9111040; 9169836; 9244302; 9590294; 9620803; 9653148; 10077672; 10079256; 10082551; 10206645; 10221902; 10637481; 10669757; 10713164; 10747963; 10837024; 10882063; 10935626; 10940313; 11006133; 11101851; 11112321; 11226752; 11390662; 11404076; 11418662; 11425854; 11511084; 11518718; 11564735; 11585921; 11604490; 11604511; 11700865; 11739188; 11777909; 11827460; 11836628; 11848684; 11940670; 11964309; 11978185; 11997524; 12048239; 12050162; 12065598; 12123574; 12145413; 12208848; 12357247; 12370315; 12370358; 12374741; 12477932; 12482957; 12486116; 12496471; 12509463; 12527910; 12532332; 12644465; 12682059; 12697902; 12768030; 12781689; 12795601; 12829602; 12913000; 12960155; 14567914; 14583609; 14602722; 14638857; 14645224; 14670925; 14678992; 14726396; 14756819; 14762442; 14996707; 15044485; 15058751; 15146197; 15213460; 15240571; 15280477; 15448134; 15472075; 15485896; 15492044; 15492845; 15546612; 15563463; 15563588; 15576031; 15650752; 15756589; 15774577; 15781650; 15817159; 15824732; 15904468; 15976178; 15987768; 16011479; 16025100; 16079893; 16096376; 16136053; 16160079; 16169070; 16179393; 16239965; 16287852; 16298817; 16317090; 16319921; 16322473; 16344560; 16365048; 16378632; 16434391; 16449526; 16501043; 16507111; 16510869; 16530044; 16536739; 16608439; 16618808; 16622004; 16651424; 16688224; 16707600; 16713569; 16729972; 16738328; 16785210; 16822655; 16871543; 16880534; 16887975; 16951331; 16990763; 17008890; 17028268; 17046738; 17090547; 17107915; 17114293; 17186020; 17252014; 17284587; 17301032; 17309564; 17316355; 17317671; 17318174; 17344417; 17353266; 17368826; 17392684; 17404512; 17425682; 17434929; 17497677; 17513037; 17526737; 17560996; 17573339; 17575125; 17604336; 17636029; 17646408; 17646409; 17652726; 17662764; 17664272; 17671232; 17716607; 17804701; 17822320; 17849174; 17851046; 17873882; 17874453; 17901244; 17920003; 17922104; 17927876; 17948123; 17967789; 17980397; 17984306; 17991315; 18055449; 18056171; 18069660; 18079963; 18084619; 18155729; 18184405; 18192230; 18192969; 18219106; 18239137; 18292500; 18292942; 18296446; 18296609; 18311147; 18320325; 18347015; 18354251; 18359760; 18411416; 18427106; 18440314; 18449208; 18456406; 18469855; 18490439; 18497996; 18549623; 18552977; 18559519; 18560356; 18570928; 18593473; 18593716; 18593923; 18593928; 18593982; 18604200; 18625637; 18628966; 18633435; 18660822; 18663143; 18663146; 18664540; 18703315; 18758479; 18758480; 18777195; 18844067; 18924608; 18984862; 19000719; 19008176; 19023031; 19025652; 19047145; 19057901; 19074836; 19091404; 19109228; 19118200; 19122673; 19147749; 19151708; 19151773; 19160126; 19167678; 19209236; 19228774; 19234458; 19239437; 19245433; 19247952; 19339697; 19340001; 19349467; 19351817; 19376776; 19396152; 19404845; 19407245; 19453261; 19479935; 19491270; 19503073; 19549918; 19550121; 19590514; 19603167; 19604236; 19631984; 19635999; 19680556; 19682396; 19686049; 19695258; 19700410; 19701457; 19704010; 19717984; 19724860; 19724883; 19725072; 19728763; 19751190; 19771395; 19778842; 19794083; 19799080; 19800882; 19808903; 19812212; 19838210; 19847202; 19850743; 19901516; 19914349; 19923082; 19953094; 19956862; 20008221; 20012562; 20036815; 20040020; 20052673; 20058190; 20060575; 20069356; 20106965; 20118921; 20145124; 20146266; 20147635; 20154720; 20193271; 20193370; 20193454; 20194747; 20204271; 20206691; 20208568; 20336604; 20339081; 20346213; 20347265; 20348013; 20348880; 20351182; 20351309; 20368328; 20372862; 20388374; 20418862; 20442780; 20443831; 20444726; 20454918; 20459529; 20479883; 20490451; 20491628; 20515335; 20517681; 20538790; 20551051; 20554499; 20573067; 20578140; 20683149; 20720151; 20730882; 20736329; 20740684; 20800871; 20801121; 20812035; 20813007; 20817637; 20819128; 20819778; 20823234; 20827750; 20861909; 20861920; 20930168; 20944675; 20950370; 20951801; 20962575; 20965628; 20978353; 21042738; 21052088; 21056041; 21078624; 21119685; 21124806; 21124883; 21139048; 21145176; 21147854; 21165952; 21196490; 21224848; 21238798; 21245387; 21251836; 21277031; 21280156; 21302811; 21308734; 21326611; 21342503; 21362320; 21398698; 21420785; 21457232; 21463919; 21464222; 21466361; 21471203; 21471519; 21480340; 21481777; 21498615; 21516124; 21518768; 21556011; 21558417; 21602795; 21622856; 21625236; 21629222; 21631271; 21632454; 21643850; 21665937; 21667253; 21670202; 21673954; 21679465; 21685328; 21737748; 21743299; 21756827; 21761283; 21768114; 21771876; 21775206; 21778948; 21785827; 21798893; 21798897; 21807868; 21810559; 21818118; 21820430; 21835957; 21841793; 21857154; 21868761; 21869831; 21876634; 21880637; 21881870; 21892607; 21892768; 21906983; 21909072; 21938432; 21939555; 21963094; 21979940; 21984373; 21989054; 21993452; 21993533; 21993686; 22004682; 22006338; 22020917; 22022427; 22027644; 22030773; 22038626; 22052196; 22065781; 22066479; 22075160; 22075757; 22077063; 22080880; 22084425; 22093097; 22100894; 22101766; 22110751; 22116551; 22118425; 22123293; 22128911; 22143792; 22150311; 22171922; 22173954; 22182918; 22194996; 22196886; 22197545; 22199353; 22207691; 22210878; 22218807; 22225590; 22249266; 22271085; 22275240; 22279105; 22311010; 22325781; 22330335; 22348144; 22348356; 22349824; 22357466; 22363487; 22378079; 22388891; 22393458; 22424712; 22438124; 22463491; 22479394; 22490851; 22506064; 22510873; 22526456; 22535768; 22546285; 22571487; 22581828; 22585622; 22619094; 22665268; 22673746; 22695916; 22705236; 22718117; 22768113; 22778262; 22780927; 22781569; 22781716; 22809957; 22814294; 22833359; 22846929; 22863622; 22877736; 22902365; 22914328; 22915591; 22922832; 22929735; 22940701; 22954590; 22956186; 22965987; 22968660; 22972921; 22986536; 23022380; 23028920; 23040356; 23049092; 23053901; 23067214; 23072667; 23074278; 23086478; 23087364; 23102684; 23103515; 23108395; 23124208; 23124652; 23138133; 23161436; 23161489; 23167503; 23171551; 23179396; 23225326; 23226395; 23235341; 23239744; 23243274; 23252402; 23289374; 23295735; 23300792; 23300864; 23319603; 23339193; 23341344; 23349303; 23349727; 23380742; 23396245; 23409141; 23423517; 23430952; 23435461; 23444212; 23454378; 23455394; 23468978; 23500524; 23531595; 23542114; 23558524; 23568245; 23569274; 23576735; 23578328; 23583836; 23589286; 23589494; 23594289; 23603912; 23620080; 23625115; 23630292; 23632994; 23640488; 23642368; 23651443; 23665520; 23671619; 23688168; 23707238; 23713656; 23733784; 23734977; 23742774; 23743248; 23749167; 23775085; 23776410; 23788636; 23798201; 23821658; 23839946; 23860447; 23881612; 23886940; 23893575; 23899513; 23902763; 23916913; 23924630; 23938602; 23974200; 23990360; 23999936; 24019071; 24085301; 24095799; 24108462; 24109236; 24113181; 24113472; 24122995; 24140425; 24166518; 24216479; 24255178; 24308033; 24321094; 24424791 notch 1 Ensembl:ENSG00000148400 HGNC:7881 HPRD:01827 MIM:190198 Vega:OTTHUMG00000020935 NOTCH1 Bin Zhao, Yue Liu, Oliver He PYY4 WEB: http://www.ncbi.nlm.nih.gov/gene NPY neuropeptide Y 4852 7p15.1 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0001664 (EC: IEA); GO_0004930 (EC: TAS, PMID: 1321422); GO_0005102 (EC: TAS, PMID: 10698177); GO_0005184 (EC: TAS, PMID: 2427515); GO_0005246 (EC: TAS, PMID: 8132547); GO_0005576 (EC: TAS); GO_0005615 (EC: ISS); GO_0005623 (EC: TAS, PMID: 2444979); GO_0006816 (EC: TAS, PMID: 8132547); GO_0006928 (EC: TAS, PMID: 10488139); GO_0007187 (EC: TAS, PMID: 8132547); GO_0007218 (EC: IEA); GO_0007268 (EC: TAS, PMID: 10557353); GO_0007586 (EC: NAS, PMID: 8421707); GO_0007610 (EC: TAS, PMID: 9845072); GO_0007631 (EC: TAS, PMID: 10698177); GO_0008015 (EC: NAS, PMID: 8421707); GO_0008217 (EC: IEA); GO_0008283 (EC: TAS, PMID: 10488139); GO_0008343 (EC: ISS); GO_0021954 (EC: IEP); GO_0021987 (EC: IEP, PMID: 9067840); GO_0031175 (EC: IEP); GO_0032100 (EC: ISS) PMID: 1321422; 1425680; 2427515; 2444979; 3753985; 3839058; 6589611; 7493937; 7559383; 7782078; 8132547; 8421707; 9001438; 9008359; 9067840; 9845072; 10488139; 10557353; 10561544; 10698177; 10770181; 11196643; 11278902; 11325787; 11410744; 11422604; 11689216; 11696660; 11814620; 11884208; 11914038; 11932939; 12007534; 12015205; 12034130; 12081635; 12106685; 12187394; 12187924; 12209475; 12215082; 12454738; 12477932; 12479530; 12544000; 12609745; 12646110; 12663466; 12689610; 12690205; 12759898; 12782203; 12818415; 12843176; 12853948; 12875921; 12878188; 12932169; 14628185; 14747236; 14751436; 15126561; 15165988; 15201542; 15336593; 15364898; 15485137; 15489334; 15597110; 15604093; 15625769; 15680469; 15736042; 15759545; 15797951; 15847953; 15850450; 15894681; 15897713; 15926114; 15959845; 16135994; 16136022; 16339211; 16382997; 16382999; 16383000; 16383001; 16383009; 16383010; 16390370; 16459651; 16500360; 16568137; 16785149; 16912140; 17066479; 17154253; 17187020; 17268419; 17305733; 17325259; 17366345; 17516289; 17525122; 17554476; 17695723; 17702963; 17948870; 17984244; 18031993; 18037100; 18043699; 18054939; 18055304; 18211417; 18241322; 18257117; 18279562; 18385673; 18420205; 18423883; 18461271; 18499283; 18577758; 18636124; 18641693; 18715275; 18815063; 18828811; 18974842; 18996102; 19056482; 19058789; 19086053; 19119412; 19150389; 19240061; 19245788; 19264362; 19289742; 19309436; 19367093; 19404163; 19423065; 19491387; 19566775; 19587357; 19619519; 19620246; 19699258; 19804960; 19846279; 19854625; 19865784; 19874574; 19913121; 19913525; 19942238; 20033074; 20037921; 20138117; 20164781; 20173430; 20180986; 20308990; 20351714; 20435026; 20452482; 20453000; 20459474; 20468064; 20531438; 20543711; 20554694; 20602615; 20628086; 20648632; 20673868; 20675276; 20676138; 20691708; 20734064; 20823688; 20832114; 20945961; 21041608; 21047193; 21145602; 21190576; 21273004; 21303710; 21346312; 21396710; 21426768; 21468772; 21626172; 21640760; 21746772; 21796371; 21849543; 21898706; 21917383; 21937627; 21988832; 22143932; 22289186; 22308535; 22328461; 22393040; 22492775; 22584873; 22632858; 22808091; 22849656; 22941950; 22966009; 22979996; 22985695; 23021333; 23074243; 23083763; 23107365; 23110814; 23116540; 23122776; 23277265; 23390522; 23403409; 23407263; 23457218; 23459936; 23468908; 23599389; 23624317; 23652383; 24289328 neuropeptide Y Ensembl:ENSG00000122585 HGNC:7955 HPRD:01214 MIM:162640 Vega:OTTHUMG00000022973 NPY Bin Zhao, Yue Liu, Oliver He HDNF NGF-2 NGF2 NT-3 NT3 WEB: http://www.ncbi.nlm.nih.gov/gene NTF3 neurotrophin 3 4908 12p13 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000187 (EC: IDA); GO_0002092 (EC: IDA); GO_0005102 (EC: TAS, PMID: 2236018); GO_0005165 (EC: IEA); GO_0005576 (EC: IEA); GO_0007165 (EC: TAS, PMID: 2236018); GO_0007169 (EC: IDA); GO_0007267 (EC: TAS, PMID: 2236018); GO_0007274 (EC: IEA); GO_0007399 (EC: TAS, PMID: 1542658); GO_0007403 (EC: IEA); GO_0007411 (EC: IEA); GO_0007420 (EC: IEA); GO_0007422 (EC: IEA); GO_0008083 (EC: IDA); GO_0008284 (EC: IDA); GO_0008544 (EC: IEA); GO_0016023 (EC: IEA); GO_0021675 (EC: IEA); GO_0030335 (EC: IDA); GO_0032148 (EC: IDA); GO_0032856 (EC: IDA); GO_0033138 (EC: IDA); GO_0042056 (EC: IDA); GO_0042490 (EC: IEA); GO_0042552 (EC: IEA); GO_0043524 (EC: IEA); GO_0045687 (EC: IEA); GO_0045944 (EC: IEA); GO_0048406 (EC: IEA); GO_0048484 (EC: IEA); GO_0050731 (EC: IDA); GO_0050732 (EC: IDA); GO_0050804 (EC: IEA); GO_0050918 (EC: IDA); GO_0050930 (EC: IDA); GO_0051145 (EC: IEA); GO_2000251 (EC: IDA) PMID: 1542658; 1645620; 1889806; 1889807; 2025430; 2236018; 2344409; 2365067; 7514502; 7703225; 7733919; 7991545; 8621424; 8819011; 8841198; 8925252; 9488719; 9756741; 9973222; 11580868; 11877300; 11920853; 12107412; 12397373; 12477932; 12598727; 12710933; 12900521; 15146197; 15365216; 15474906; 15489334; 15544837; 15589528; 15770067; 15843147; 16441896; 16786155; 17112518; 17192954; 17207965; 17234344; 17698064; 18069415; 18179783; 18203754; 18305571; 18313696; 18336001; 18428117; 18438927; 18438945; 18596692; 19086053; 19357934; 19369542; 19453261; 19598235; 19680743; 20060128; 20160348; 20219210; 20360537; 20379614; 20576502; 20597688; 21085492; 21261755; 21392742; 21698095; 21720807; 21787840; 21996274; 22036954; 22158057; 22192858; 22454143; 22459634; 23001042; 23027130; 23038618; 23075484; 23149719; 23185507; 23426664; 23522042; 23869086 neurotrophin 3 Ensembl:ENSG00000185652 HGNC:8023 HPRD:01219 MIM:162660 Vega:OTTHUMG00000168649 NTF3 Bin Zhao, Yue Liu, Oliver He GLC10 GLC1O NT-4 NT-4/5 NT-5 NT4 NT5 NTF5 WEB: http://www.ncbi.nlm.nih.gov/gene NTF4 neurotrophin 4 4909 19q13.3 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005576 (EC: ISS, PMID: 10908605); GO_0005788 (EC: ISS, PMID: 925010); GO_0007402 (EC: ISS, PMID: 10681461); GO_0007616 (EC: ISS, PMID: 10869436); GO_0008052 (EC: ISS, PMID: 10479455); GO_0008083 (EC: IEA); GO_0008344 (EC: ISS, PMID: 10681461); GO_0008544 (EC: ISS, PMID: 9973328); GO_0042490 (EC: IEA) PMID: 925010; 1313578; 1496419; 1742028; 7541633; 7703225; 8061955; 8241191; 8873083; 9519408; 9973328; 10388563; 10479455; 10490030; 10631974; 10681461; 10869436; 10908605; 11263982; 11738045; 11855816; 12397373; 12477932; 12900521; 15258592; 15489334; 15987945; 16316409; 16648150; 16648236; 18179783; 18203754; 18305571; 18980528; 19081579; 19086053; 19598235; 19765683; 20175187; 20215012; 20219210; 20447632; 20463313; 20806036; 21330466; 21350004; 21988832; 22036954; 22192858; 22815630; 23869086 neurotrophin 4 Ensembl:ENSG00000225950 HGNC:8024 HPRD:01220 MIM:162662 NTF4 Bin Zhao, Yue Liu, Oliver He MTC TRK TRK1 TRKA Trk-A p140-TrkA WEB: http://www.ncbi.nlm.nih.gov/gene NTRK1 neurotrophic tyrosine kinase, receptor, type 1 4914 1q21-q22 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000186 (EC: TAS); GO_0004714 (EC: IDA, PMID: 15488758); GO_0005166 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12237455); GO_0005524 (EC: IEA); GO_0005768 (EC: TAS); GO_0005769 (EC: ISS); GO_0005770 (EC: ISS); GO_0005886 (EC: ISS); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 15488758); GO_0006468 (EC: IDA, PMID: 15488758); GO_0007169 (EC: TAS); GO_0007190 (EC: TAS); GO_0007202 (EC: TAS); GO_0007264 (EC: TAS); GO_0007265 (EC: TAS); GO_0007411 (EC: IEA); GO_0007568 (EC: IEA); GO_0007611 (EC: IEA); GO_0008285 (EC: IDA, PMID: 15488758); GO_0008285 (EC: IDA, Qualifier: NOT, PMID: 15488758); GO_0009314 (EC: IEA); GO_0009986 (EC: IEA); GO_0010465 (EC: IDA, PMID: 15488758); GO_0010623 (EC: ISS); GO_0010976 (EC: IDA, PMID: 15488758); GO_0010976 (EC: IDA, Qualifier: NOT, PMID: 15488758); GO_0014823 (EC: IEA); GO_0018108 (EC: IDA, PMID: 15488758); GO_0021553 (EC: IEA); GO_0030183 (EC: IEA); GO_0030424 (EC: IEA); GO_0030425 (EC: IEA); GO_0031410 (EC: IEA); GO_0031667 (EC: IEA); GO_0031901 (EC: IEA); GO_0031902 (EC: IEA); GO_0032320 (EC: IDA, PMID: 15488758); GO_0032320 (EC: IDA, Qualifier: NOT, PMID: 15488758); GO_0042490 (EC: IEA); GO_0042493 (EC: IEA); GO_0042803 (EC: IDA, PMID: 17196528); GO_0043025 (EC: IEA); GO_0043068 (EC: ISS); GO_0043121 (EC: TAS, PMID: 9290260); GO_0043234 (EC: ISS); GO_0043235 (EC: IDA); GO_0043524 (EC: ISS); GO_0045471 (EC: IEA); GO_0045766 (EC: IDA, PMID: 15488758); GO_0046579 (EC: IDA, PMID: 15488758); GO_0046579 (EC: IDA, Qualifier: NOT, PMID: 15488758); GO_0046777 (EC: IDA, PMID: 15488758); GO_0046875 (EC: IEA); GO_0048011 (EC: IDA, PMID: 15488758); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0048406 (EC: IDA, PMID: 15488758); GO_0048406 (EC: IDA, Qualifier: NOT, PMID: 15488758); GO_0048485 (EC: ISS); GO_0048678 (EC: IEA); GO_0050965 (EC: IEA); GO_0050966 (EC: IEA); GO_0051092 (EC: IDA, PMID: 15488758); GO_0051599 (EC: IEA); GO_0051602 (EC: IEA); GO_0051968 (EC: IEA); GO_0060009 (EC: IEA); GO_0060385 (EC: ISS); GO_0070374 (EC: IDA, PMID: 15488758); GO_0070374 (EC: IDA, Qualifier: NOT, PMID: 15488758); GO_0071316 (EC: IEA); GO_1990090 (EC: ISS) PMID: 1463607; 1532241; 1656363; 1695324; 1706478; 1715690; 1849459; 1850821; 2869410; 2927393; 2966065; 7509449; 7510697; 7541035; 7542991; 7565764; 7601468; 7657647; 7806500; 7823156; 8155326; 8183561; 8226808; 8325889; 8384556; 8524391; 8577769; 8610109; 8621424; 8696348; 8889548; 8943228; 8957089; 9069267; 9099755; 9182757; 9282923; 9290260; 9341772; 9507002; 9856458; 9867838; 9927421; 10090906; 10092678; 10103137; 10233776; 10329710; 10330344; 10388563; 10391209; 10443680; 10490030; 10567924; 10629055; 10679771; 10708759; 10712923; 10747026; 10748052; 10861667; 10982191; 11071380; 11147812; 11150334; 11157096; 11159935; 11244088; 11251075; 11310631; 11466412; 11520933; 11668614; 11705863; 11729324; 11733534; 11738045; 11850535; 11859925; 12006576; 12102460; 12150951; 12208732; 12210794; 12237455; 12406349; 12446789; 12471037; 12477932; 12536040; 14642435; 14691455; 14985763; 14988025; 15024033; 15159601; 15167895; 15273715; 15362372; 15488758; 15489334; 15513915; 15523689; 15637590; 15753086; 15870692; 15950763; 15961390; 16091303; 16113645; 16138253; 16181609; 16246731; 16275928; 16284401; 16373086; 16483615; 16546643; 16586073; 16701206; 16704535; 16710414; 16786155; 16805430; 16860569; 16862449; 16919030; 16935282; 16939974; 16996570; 17143529; 17196528; 17267689; 17447019; 17531524; 17548467; 17617666; 17619016; 17635673; 17667845; 17671718; 17673289; 17850422; 17971243; 18005706; 18072090; 18077166; 18174161; 18203754; 18221326; 18270328; 18305571; 18319596; 18322713; 18419753; 18427551; 18457658; 18678285; 18719857; 18727839; 18780967; 19086053; 19115484; 19120874; 19167335; 19169037; 19177265; 19250380; 19330021; 19386345; 19399531; 19417027; 19435634; 19453261; 19564412; 19598235; 19635108; 19651702; 19730683; 19734938; 19749791; 19758420; 19816090; 19883730; 19913121; 19945432; 19953087; 19957796; 20003389; 20186105; 20209132; 20219210; 20301434; 20301726; 20424473; 20542022; 20600627; 20628086; 20663926; 20680486; 20854189; 20943663; 20977883; 21123453; 21137076; 21139137; 21150695; 21154590; 21184737; 21236475; 21295543; 21317683; 21321391; 21332718; 21397006; 21419569; 21429417; 21503896; 21570973; 21645891; 21728718; 21849536; 21990266; 22128158; 22138126; 22272270; 22343487; 22410777; 22445970; 22454143; 22539856; 22561027; 22623531; 22653642; 22782892; 22902478; 22932111; 22939624; 22954667; 22992069; 23266087; 23400852; 23471969; 23489213; 23569426; 23589303; 23746174; 23788249; 23841091; 23869086; 24162815; 24369899 neurotrophic tyrosine kinase, receptor, type 1 Ensembl:ENSG00000198400 HGNC:8031 HPRD:01869 MIM:191315 Vega:OTTHUMG00000041304 NTRK1 Bin Zhao, Yue Liu, Oliver He GP145-TrkB TRKB trk-B WEB: http://www.ncbi.nlm.nih.gov/gene NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 RP11-263K15.1 9q22.1 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0001570 (EC: IEA); GO_0001764 (EC: ISS); GO_0005524 (EC: IEA); GO_0005829 (EC: IEA); GO_0005887 (EC: IDA, PMID: 15494731); GO_0007169 (EC: TAS); GO_0007190 (EC: TAS); GO_0007528 (EC: IEA); GO_0007568 (EC: IEA); GO_0007612 (EC: ISS); GO_0007616 (EC: IEA); GO_0007631 (EC: IEA); GO_0008284 (EC: ISS); GO_0009986 (EC: IEA); GO_0010008 (EC: IEA); GO_0010628 (EC: ISS); GO_0010976 (EC: ISS); GO_0010996 (EC: IEA); GO_0014047 (EC: IEA); GO_0014068 (EC: ISS); GO_0014069 (EC: IEA); GO_0021954 (EC: ISS); GO_0021987 (EC: ISS); GO_0030182 (EC: ISS); GO_0030426 (EC: IEA); GO_0031547 (EC: IMP, PMID: 15494731); GO_0032314 (EC: ISS); GO_0035584 (EC: IEA); GO_0042490 (EC: IEA); GO_0042803 (EC: ISS); GO_0043025 (EC: IEA); GO_0043121 (EC: IDA, PMID: 11738045); GO_0043121 (EC: ISS); GO_0043195 (EC: IEA); GO_0043197 (EC: IEA); GO_0043235 (EC: IDA); GO_0043410 (EC: ISS); GO_0043524 (EC: ISS); GO_0045211 (EC: IEA); GO_0046548 (EC: IEA); GO_0046777 (EC: ISS); GO_0046875 (EC: IEA); GO_0046928 (EC: IEA); GO_0048011 (EC: TAS); GO_0048403 (EC: ISS); GO_0048709 (EC: IEA); GO_0048786 (EC: IEA); GO_0048935 (EC: IEA); GO_0050772 (EC: ISS); GO_0050773 (EC: IEA); GO_0051896 (EC: IEA); GO_0051968 (EC: IEA); GO_0060076 (EC: IEA); GO_0060175 (EC: IMP, PMID: 15494731); GO_0060291 (EC: IEA); GO_2000811 (EC: IEA) PMID: 1645620; 1710174; 7574684; 7679912; 7759111; 7789988; 7823156; 7936202; 8621424; 8895847; 9195161; 9312147; 9507002; 9573364; 9648856; 9856458; 9927421; 10092678; 10386953; 10388563; 10490030; 10533983; 10631974; 11157096; 11162451; 11251075; 11263982; 11432792; 11738045; 11798182; 11849294; 11855816; 12006576; 12074588; 12237455; 12367511; 12419535; 12471037; 12477932; 12719654; 12808116; 12912764; 12921913; 14617818; 14702039; 15024057; 15167895; 15304335; 15329723; 15389758; 15489334; 15494731; 15513915; 15637590; 15647480; 15657181; 15838534; 16034442; 16051641; 16113645; 16335952; 16647839; 16648150; 16701206; 16713371; 16713586; 16786155; 16805430; 16862449; 16939974; 16964397; 17008023; 17200667; 17570738; 17611278; 17616679; 17674765; 17720314; 17873329; 17884018; 17889702; 17918233; 17971243; 18075316; 18201274; 18203754; 18253057; 18286198; 18293376; 18319596; 18428117; 18457658; 18511296; 18534558; 18595003; 18637190; 18678285; 18727839; 18780967; 18959266; 18992902; 19018715; 19086053; 19087522; 19124685; 19156168; 19170129; 19268276; 19307055; 19363525; 19365399; 19386345; 19403818; 19417027; 19453261; 19488044; 19548263; 19598235; 19635108; 19641488; 19741136; 19765683; 19801649; 19816090; 19844206; 19874574; 19879330; 19885622; 19913121; 19927149; 19953087; 20014955; 20083228; 20101235; 20124106; 20132184; 20156366; 20186105; 20193039; 20202475; 20219210; 20379614; 20428771; 20463055; 20468064; 20610389; 20615547; 20628086; 20662941; 20673758; 20694504; 20703101; 20811716; 20877300; 20878119; 21047554; 21079983; 21126736; 21187387; 21192928; 21215389; 21223646; 21239439; 21242122; 21295543; 21330466; 21379385; 21414899; 21419569; 21426646; 21552290; 21612826; 21670725; 21711518; 21728718; 21739244; 21750702; 21795612; 21802740; 21849537; 21849550; 21966426; 21988832; 21999199; 22020324; 22028443; 22209410; 22258407; 22322843; 22341689; 22343487; 22361863; 22393127; 22425982; 22426239; 22490895; 22609366; 22710966; 22719055; 22842573; 22886570; 22902478; 22906736; 22939624; 23058367; 23064382; 23086941; 23124249; 23137999; 23185507; 23192594; 23277131; 23315174; 23332094; 23416450; 23420490; 23422506; 23598407; 23656788; 23861540; 23869086; 23936232; 24047966 neurotrophic tyrosine kinase, receptor, type 2 Ensembl:ENSG00000148053 HGNC:8032 HPRD:02712 MIM:600456 Vega:OTTHUMG00000020120 NTRK2 Bin Zhao, Yue Liu, Oliver He TRKC gp145(trkC) WEB: http://www.ncbi.nlm.nih.gov/gene NTRK3 neurotrophic tyrosine kinase, receptor, type 3 4916 15q25 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0000187 (EC: IDA); GO_0001764 (EC: IEA); GO_0001933 (EC: IDA); GO_0002039 (EC: IPI); GO_0004714 (EC: IEA); GO_0005030 (EC: IDA); GO_0005524 (EC: IEA); GO_0005737 (EC: IEA); GO_0005887 (EC: IEA); GO_0007169 (EC: IDA); GO_0008284 (EC: IDA); GO_0010628 (EC: IDA); GO_0019056 (EC: IEA); GO_0030335 (EC: IDA); GO_0032148 (EC: IDA); GO_0032856 (EC: IDA); GO_0033138 (EC: IDA); GO_0038179 (EC: IDA); GO_0042490 (EC: IEA); GO_0043121 (EC: TAS, PMID: 7806211); GO_0043235 (EC: IDA); GO_0045471 (EC: IEA); GO_0046777 (EC: IEA); GO_0046875 (EC: IEA); GO_0048665 (EC: IEA); GO_0048678 (EC: IEA); GO_0048691 (EC: IEA); GO_0048712 (EC: IEA); GO_0050927 (EC: IDA); GO_0051412 (EC: IEA); GO_0060548 (EC: IEA); GO_0071300 (EC: IEA); GO_0090102 (EC: IEA); GO_2000251 (EC: IDA) PMID: 1326636; 1653651; 7657612; 7806211; 7823156; 7828539; 8344249; 8619474; 8621424; 8889548; 8895847; 9110174; 9195161; 9197281; 9462753; 9488719; 9648868; 9778053; 9856458; 9927421; 9973222; 10027399; 10092678; 10764727; 11157096; 11205744; 11877382; 12006576; 12034707; 12210087; 12237455; 12399943; 12450792; 12471037; 12477932; 12927579; 14668342; 15167446; 15167895; 15198123; 15247919; 15312164; 15513915; 15932601; 16344560; 16537434; 16647839; 16648236; 16786155; 16826429; 16862449; 16941478; 17971243; 18068631; 18179783; 18203754; 18293376; 18319596; 18336001; 18347002; 18367154; 18428117; 18616610; 18639687; 18713973; 19011601; 19040714; 19086053; 19156760; 19179422; 19187638; 19344762; 19351817; 19370765; 19417027; 19453261; 19556619; 19598235; 19680743; 19893451; 20078941; 20160348; 20219210; 20379614; 20554328; 20802235; 21070662; 21139137; 21295543; 21392742; 21401966; 21552290; 21617231; 21728718; 21788388; 21832049; 21988832; 22265740; 22343487; 22388998; 22404213; 22939624; 23027130; 23332094; 23341610; 23416450; 23453885; 23832765; 23869086; 23874207; 24145651 neurotrophic tyrosine kinase, receptor, type 3 Ensembl:ENSG00000140538 HGNC:8033 HPRD:01870 MIM:191316 Vega:OTTHUMG00000148677 NTRK3 Bin Zhao, Yue Liu, Oliver He NMN-125 NN NT NT/N NTS1 WEB: http://www.ncbi.nlm.nih.gov/gene NTS neurotensin 4922 12q21 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0005184 (EC: IEA); GO_0005515 (EC: IPI); GO_0005576 (EC: TAS); GO_0007165 (EC: NAS, PMID: 8954810); GO_0030133 (EC: IEA); GO_0050880 (EC: IEA) PMID: 409699; 1436492; 3525564; 3670596; 6754769; 7791794; 7836437; 8075503; 8719037; 8770919; 8869556; 8954810; 9530155; 9756851; 11278902; 11559354; 11801734; 11811984; 11815627; 11906607; 11912133; 11922768; 12150975; 12473660; 12477932; 12531461; 12609826; 14699144; 14743366; 15123666; 15358593; 15489334; 15623535; 16087676; 16519961; 16754659; 16984735; 17068197; 17207965; 17289170; 17570131; 17644423; 17870207; 18048355; 18577758; 18624930; 19086053; 19393580; 19878995; 19932148; 20138826; 20468064; 20731814; 20810387; 20858966; 21030593; 21212273; 21233215; 21272935; 21508335; 21542591; 21623207; 21806946; 21994122; 22416137; 22700584; 22825476; 22849656; 23064014; 23109725; 23418512; 23436714; 23962427; 24000330; 24198343 neurotensin Ensembl:ENSG00000133636 HGNC:8038 HPRD:08878 MIM:162650 Vega:OTTHUMG00000169832 NTS Bin Zhao, Yue Liu, Oliver He OCTD WEB: http://www.ncbi.nlm.nih.gov/gene OTC ornithine carbamoyltransferase 5009 Xp21.1 20140408 9606 X protein-coding Official from a nomenclature committee GO_0000050 (EC: IDA, PMID: 2556444); GO_0000050 (EC: IEA); GO_0000050 (EC: TAS); GO_0001889 (EC: IEA); GO_0004585 (EC: EXP); GO_0004585 (EC: IDA, PMID: 2556444); GO_0005543 (EC: IEA); GO_0005739 (EC: IDA); GO_0005743 (EC: IEA); GO_0005759 (EC: NAS, PMID: 6372096); GO_0005759 (EC: TAS); GO_0006526 (EC: IEA); GO_0006593 (EC: IDA, PMID: 2556444); GO_0007494 (EC: IEA); GO_0010043 (EC: IEA); GO_0016597 (EC: IEA); GO_0019240 (EC: IDA, PMID: 2556444); GO_0032868 (EC: IEA); GO_0034641 (EC: TAS); GO_0042301 (EC: IEA); GO_0042493 (EC: IEA); GO_0044281 (EC: TAS); GO_0070207 (EC: IEA); GO_0070781 (EC: IEA); GO_0097272 (EC: IMP, PMID: 2556444) PMID: 1353535; 1480464; 1602151; 1627356; 1671317; 1721894; 1757964; 2035531; 2037279; 2208768; 2347583; 2474822; 2556444; 2722850; 2741942; 2836378; 2843770; 2983225; 3170748; 3782067; 3891325; 3895227; 3943133; 6169723; 6372096; 6494904; 6942417; 7085676; 7474905; 7627182; 7860064; 7860066; 7951259; 8019569; 8081373; 8081398; 8099056; 8364586; 8530002; 8544185; 8807340; 8830175; 8863155; 8956038; 8956045; 9056557; 9065786; 9143919; 9266388; 9286441; 9756929; 9852088; 10070627; 10405441; 10502831; 10565370; 10737985; 10813810; 11260212; 11768581; 11793468; 11793483; 12083811; 12477932; 12516615; 12618087; 15300856; 15489334; 15692798; 15772651; 16712791; 16786505; 17041896; 17570074; 17570354; 17893704; 18029348; 18030415; 18204299; 18983895; 19138872; 19359120; 19475717; 19574962; 19748344; 19893582; 20127982; 20817516; 21956151; 24006547 ornithine carbamoyltransferase Ensembl:ENSG00000036473 HGNC:8512 HPRD:02408 HPRD:08947 MIM:300461 Vega:OTTHUMG00000022727 OTC Bin Zhao, Yue Liu, Oliver He OXCT SCOT WEB: http://www.ncbi.nlm.nih.gov/gene OXCT1 3-oxoacid CoA transferase 1 5019 5p13.1 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0005739 (EC: IDA); GO_0005739 (EC: NAS, PMID: 10964512); GO_0005759 (EC: TAS); GO_0007420 (EC: IEA); GO_0007507 (EC: IEA); GO_0007584 (EC: IEA); GO_0008260 (EC: IMP, PMID: 10964512); GO_0008260 (EC: TAS); GO_0009725 (EC: IEA); GO_0014823 (EC: IEA); GO_0032024 (EC: IEA); GO_0042182 (EC: IEA); GO_0042493 (EC: IEA); GO_0042594 (EC: IEA); GO_0042803 (EC: NAS, PMID: 10964512); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0045471 (EC: IEA); GO_0046950 (EC: IMP, PMID: 9671268); GO_0046950 (EC: TAS); GO_0046952 (EC: TAS); GO_0060612 (EC: IEA); GO_0071229 (EC: IEA); GO_0071333 (EC: IEA) PMID: 1405472; 6150478; 8751852; 9380443; 9671268; 10964512; 11756565; 12477932; 14702039; 15489334; 15496607; 16765626; 17706444; 18029348; 18648183; 19296078; 20381070; 20652411; 20877624; 21163940; 21296660; 21565611; 21791085; 22863883; 22939629 3-oxoacid CoA transferase 1 Ensembl:ENSG00000083720 HGNC:8527 HPRD:02001 MIM:601424 Vega:OTTHUMG00000094783 OXCT1 Bin Zhao, Yue Liu, Oliver He P2X7 WEB: http://www.ncbi.nlm.nih.gov/gene P2RX7 purinergic receptor P2X, ligand-gated ion channel, 7 5027 12q24 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0001530 (EC: ISS); GO_0001614 (EC: IDA, PMID: 9038151); GO_0002028 (EC: ISS, PMID: 17785580); GO_0004931 (EC: IDA, PMID: 9038151); GO_0005102 (EC: ISS, PMID: 17785580); GO_0005524 (EC: IC, PMID: 9038151); GO_0005639 (EC: IBA); GO_0005737 (EC: ISS); GO_0005886 (EC: ISS, PMID: 17785580); GO_0005886 (EC: TAS); GO_0005887 (EC: IC, PMID: 9038151); GO_0006812 (EC: IDA, PMID: 9038151); GO_0007166 (EC: ISS); GO_0010524 (EC: IDA, PMID: 9038151); GO_0016020 (EC: IDA, PMID: 17785580); GO_0019233 (EC: ISS); GO_0030501 (EC: ISS); GO_0032059 (EC: ISS); GO_0032060 (EC: ISS); GO_0033198 (EC: IDA, PMID: 9038151); GO_0035590 (EC: IDA, PMID: 9038151); GO_0035872 (EC: TAS); GO_0042803 (EC: NAS, PMID: 17895406); GO_0043409 (EC: ISS); GO_0045087 (EC: TAS); GO_0045779 (EC: ISS); GO_0045919 (EC: ISS); GO_0046931 (EC: IDA, PMID: 9038151); GO_0050718 (EC: IDA, PMID: 17036048); GO_0051495 (EC: ISS); GO_0051709 (EC: NAS, PMID: 17785580); GO_0051899 (EC: IDA, PMID: 9038151); GO_0097190 (EC: ISS) PMID: 8125298; 9038151; 9826911; 11150303; 11341329; 11707406; 11852049; 11943260; 12107182; 12270951; 12404161; 12422208; 12456589; 12477932; 12493261; 12586825; 12633871; 12759456; 12787128; 12874219; 12874700; 12880424; 12931211; 14510944; 14607949; 14702039; 14976257; 15004138; 15089763; 15120006; 15123679; 15155383; 15184265; 15304508; 15472991; 15475073; 15489334; 15571247; 15728711; 15777864; 15778408; 15830104; 15862308; 15896293; 15899033; 15901833; 15923180; 15942904; 15972634; 15991050; 16117789; 16228288; 16263709; 16321858; 16344560; 16424024; 16514055; 16541075; 16624800; 16673375; 16740600; 16822851; 17032903; 17036048; 17040997; 17065062; 17065105; 17095747; 17130901; 17142754; 17197037; 17257221; 17286963; 17314141; 17474147; 17482244; 17483156; 17488689; 17558311; 17785580; 17895406; 17928361; 17947359; 18040764; 18071294; 18089587; 18211888; 18268501; 18436590; 18523309; 18543274; 18545980; 18596211; 18614336; 18617511; 18676680; 18678419; 18682393; 18765670; 18801407; 18852390; 18937793; 18971257; 18987356; 19017759; 19068080; 19074885; 19076224; 19151591; 19160446; 19170196; 19186133; 19201928; 19204004; 19211924; 19225709; 19226284; 19264037; 19309360; 19328558; 19330776; 19396427; 19430700; 19453261; 19494237; 19548263; 19552691; 19625176; 19682070; 19692168; 19700502; 19748989; 19882109; 19889958; 19891999; 19913121; 19931869; 20007545; 20138022; 20164546; 20185692; 20188863; 20196868; 20226536; 20351714; 20360457; 20378545; 20379614; 20424473; 20446288; 20450227; 20453110; 20488797; 20493226; 20495003; 20508067; 20535134; 20605778; 20628086; 20661107; 20668222; 20813842; 20819262; 20837475; 20846359; 21041608; 21187936; 21205829; 21233486; 21262970; 21266468; 21335057; 21438144; 21470339; 21492831; 21508263; 21565445; 21635566; 21640086; 21645266; 21651910; 21670495; 21697458; 21821797; 21865551; 21911484; 21941410; 21978920; 21988719; 21988832; 22017219; 22048123; 22134903; 22137490; 22163032; 22183411; 22234152; 22250198; 22274585; 22295949; 22377955; 22447075; 22450808; 22461619; 22476940; 22490780; 22493010; 22505653; 22547202; 22613720; 22623165; 22662160; 22703695; 22707062; 22743305; 22768094; 22776862; 22806078; 22891241; 22898868; 22906303; 22946048; 22948816; 22952630; 22996386; 23047057; 23050672; 23095809; 23144325; 23144326; 23204228; 23210974; 23250993; 23293841; 23303206; 23319734; 23408402; 23428418; 23435013; 23479230; 23524196; 23602648; 23648388; 23691096; 23843215; 23936165; 23947898; 24013409 purinergic receptor P2X, ligand-gated ion channel, 7 Ensembl:ENSG00000089041 HGNC:8537 HPRD:03977 MIM:602566 P2RX7 Bin Zhao, Yue Liu, Oliver He HCNP HCNPpp HEL-210 HEL-S-34 PBP PEBP PEBP-1 RKIP WEB: http://www.ncbi.nlm.nih.gov/gene PEBP1 phosphatidylethanolamine binding protein 1 5037 12q24.23 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0004867 (EC: IEA); GO_0005515 (EC: IPI, PMID: 17097642); GO_0005524 (EC: IEA); GO_0005737 (EC: IEA); GO_0008429 (EC: TAS, PMID: 7637590); GO_0019899 (EC: IPI); GO_0019901 (EC: IPI); GO_0044822 (EC: IDA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1286669; 1602151; 7637590; 7641877; 7807553; 8125298; 8144042; 8738137; 9782050; 10490027; 10622376; 10757792; 11034991; 11585904; 11853019; 12421765; 12477932; 12551925; 14654844; 14766752; 15001550; 15327891; 15489334; 15782137; 16027165; 16169070; 16243812; 16513087; 16865242; 16916643; 17018026; 17030190; 17081983; 17097642; 17145707; 17179102; 17353931; 17474147; 17911631; 17952120; 18160415; 18172264; 18294816; 18329792; 18375747; 18483365; 18567796; 18781797; 18816836; 19034380; 19056867; 19096942; 19101508; 19103740; 19153603; 19165527; 19228192; 19291429; 19342899; 19357705; 19367706; 19405953; 19551145; 19564817; 19705153; 19779262; 19955695; 19957553; 20028985; 20043910; 20463977; 20533335; 20564197; 20682295; 20734161; 20739083; 20853079; 20855151; 20869966; 21074977; 21080875; 21139048; 21180766; 21303975; 21332389; 21426659; 21556737; 21565611; 21617351; 21664646; 21672326; 21685394; 21689459; 21732351; 21831839; 21873975; 21875465; 21890473; 21906983; 21963094; 21988832; 22031589; 22053931; 22102006; 22246605; 22248055; 22279539; 22292035; 22295570; 22373584; 22388727; 22460832; 22463874; 22492043; 22505648; 22536838; 22558375; 22562283; 22605662; 22662230; 22692503; 22809510; 22833545; 22855160; 22875620; 22899242; 22935977; 22939629; 22983529; 23000965; 23066033; 23066640; 23075684; 23095933; 23254962; 23259789; 23284715; 23359513; 23376254; 23460950; 23527098; 23632477; 23636063; 23674108; 23814485; 23824909; 23872143; 23991415; 24048798; 24395801 phosphatidylethanolamine binding protein 1 Ensembl:ENSG00000089220 HGNC:8630 HPRD:06850 MIM:604591 Vega:OTTHUMG00000168860 PEBP1 Bin Zhao, Yue Liu, Oliver He PAI PAI-1 PAI1 PLANH1 WEB: http://www.ncbi.nlm.nih.gov/gene SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 5054 7q22.1 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0001300 (EC: IEP, PMID: 18974388); GO_0001525 (EC: IEP, PMID: 11866539); GO_0002020 (EC: IPI, PMID: 12114510); GO_0002576 (EC: TAS); GO_0004867 (EC: IDA, PMID: 1695900); GO_0005102 (EC: IPI, Qualifier: contributes_to, PMID: 8626514); GO_0005515 (EC: IPI, PMID: 16272158); GO_0005576 (EC: IDA, PMID: 9386191); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 1695900); GO_0005886 (EC: TAS); GO_0006351 (EC: TAS); GO_0006367 (EC: TAS); GO_0007179 (EC: TAS); GO_0007596 (EC: TAS); GO_0010467 (EC: TAS); GO_0010469 (EC: IDA, PMID: 8837777); GO_0010757 (EC: IDA, PMID: 8508955); GO_0010757 (EC: IMP, PMID: 18835034); GO_0010951 (EC: IDA, PMID: 1695900); GO_0014912 (EC: IDA, PMID: 8837777); GO_0030168 (EC: TAS); GO_0030194 (EC: IMP, PMID: 9207454); GO_0030195 (EC: IC, PMID: 1695900); GO_0030198 (EC: TAS); GO_0030336 (EC: IDA, PMID: 10902815); GO_0031012 (EC: IDA, PMID: 1632457); GO_0031093 (EC: TAS); GO_0032757 (EC: IMP, PMID: 19916862); GO_0033629 (EC: IDA, PMID: 8837777); GO_0035491 (EC: IMP, PMID: 19916862); GO_0042127 (EC: IEA); GO_0042730 (EC: TAS); GO_0045766 (EC: IMP, PMID: 18835034); GO_0045944 (EC: TAS); GO_0048260 (EC: IDA, PMID: 8626514); GO_0050729 (EC: IGI, PMID: 17032919); GO_0050829 (EC: IGI, PMID: 17032919); GO_0051918 (EC: IDA, PMID: 2503541); GO_0061044 (EC: IGI, PMID: 9386191); GO_0061045 (EC: IC, PMID: 8837777); GO_0071222 (EC: IMP, PMID: 19916862); GO_0090026 (EC: IMP, PMID: 19916862); GO_1902042 (EC: IMP, PMID: 18835034); GO_2000098 (EC: IDA, PMID: 8837777); GO_2000352 (EC: IMP, PMID: 18835034) PMID: 1339823; 1435917; 1632457; 1695900; 1731226; 1870265; 2110366; 2161846; 2339362; 2430793; 2503541; 2544876; 2612914; 2820474; 2840665; 2891140; 3025016; 3026837; 3090045; 3092219; 3097076; 3132455; 3262512; 7479001; 7521069; 7522053; 7523444; 7552714; 7592875; 7892190; 8344937; 8455210; 8508955; 8607113; 8626514; 8830783; 8837777; 9065424; 9143604; 9184208; 9194591; 9202242; 9207454; 9386191; 9634700; 10209959; 10368279; 10391209; 10543954; 10731421; 10737800; 10739390; 10783396; 10902815; 10967118; 11037896; 11091191; 11113116; 11168509; 11260416; 11266465; 11289708; 11332466; 11347834; 11384978; 11385207; 11397722; 11418606; 11427204; 11454529; 11457466; 11457467; 11485022; 11522017; 11525425; 11558839; 11592048; 11734664; 11738073; 11748101; 11776328; 11780311; 11796716; 11796824; 11809921; 11816701; 11816707; 11816722; 11825444; 11827452; 11829481; 11836675; 11849662; 11858184; 11858480; 11864708; 11866539; 11877282; 11908512; 11909993; 11928807; 11934213; 11972486; 11979351; 11981424; 12006921; 12027469; 12032637; 12038776; 12057695; 12063175; 12064834; 12082592; 12086154; 12090757; 12091343; 12107743; 12110504; 12114510; 12123488; 12123491; 12124797; 12140748; 12141403; 12167592; 12181379; 12187010; 12218297; 12223472; 12353079; 12353306; 12356300; 12362251; 12362314; 12390531; 12406875; 12428096; 12431476; 12437099; 12438962; 12446192; 12468767; 12477932; 12477941; 12490312; 12499900; 12506026; 12508941; 12514663; 12518110; 12524082; 12556966; 12556967; 12589088; 12597520; 12601637; 12615788; 12632020; 12642587; 12660488; 12669121; 12670745; 12684636; 12686544; 12694086; 12694180; 12694181; 12700666; 12701125; 12707042; 12708473; 12709053; 12716314; 12719278; 12734779; 12743121; 12745435; 12748347; 12761670; 12765340; 12783120; 12801613; 12802648; 12808446; 12811828; 12816904; 12833173; 12833632; 12853948; 12856128; 12856717; 12857431; 12859287; 12867763; 12871600; 12876623; 12876625; 12888867; 12899665; 12902511; 12911596; 12958610; 12960956; 14500731; 14508198; 14515181; 14515194; 14550286; 14581151; 14585904; 14592559; 14597244; 14597935; 14605330; 14623266; 14629464; 14629474; 14631138; 14642005; 14642142; 14652637; 14653439; 14653443; 14656894; 14668616; 14669168; 14675098; 14699709; 14706682; 14718574; 14742985; 14744782; 14746139; 14769027; 14963043; 14963283; 14977839; 14983217; 14983218; 14983219; 14983227; 15001579; 15009482; 15039136; 15051600; 15067375; 15079805; 15087600; 15090858; 15096570; 15105509; 15109703; 15116245; 15116265; 15119966; 15120696; 15121769; 15131125; 15146197; 15149846; 15170393; 15175025; 15183748; 15191349; 15194475; 15198928; 15213845; 15217907; 15218974; 15234427; 15243126; 15292349; 15300646; 15309528; 15313160; 15315974; 15321757; 15328163; 15333035; 15333048; 15351855; 15353919; 15372465; 15481848; 15489334; 15493875; 15494412; 15515049; 15516780; 15528457; 15554360; 15575342; 15588467; 15611593; 15613047; 15630497; 15634264; 15646834; 15659127; 15673060; 15674349; 15677734; 15678273; 15716278; 15718495; 15772559; 15780823; 15820782; 15823189; 15824541; 15827742; 15831288; 15831362; 15837947; 15841306; 15842353; 15843979; 15853774; 15853833; 15869597; 15869613; 15879922; 15885322; 15886801; 15905170; 15907980; 15915389; 15916851; 15920032; 15935832; 15935835; 15939070; 15952129; 15978119; 15990085; 15994914; 16014034; 16020771; 16037259; 16039281; 16043164; 16061406; 16082623; 16086925; 16102055; 16102886; 16113755; 16123492; 16130596; 16148154; 16151016; 16154434; 16160004; 16172282; 16172807; 16179568; 16202290; 16210568; 16228848; 16237647; 16266514; 16270643; 16272158; 16274483; 16279946; 16307159; 16321247; 16331557; 16353042; 16356191; 16365142; 16369102; 16395714; 16409202; 16409470; 16416371; 16423881; 16424345; 16444434; 16456100; 16458133; 16466010; 16472842; 16483878; 16496609; 16502012; 16507937; 16508752; 16546843; 16567932; 16569320; 16601834; 16603315; 16622840; 16635210; 16676078; 16703752; 16706983; 16713569; 16713670; 16730474; 16735791; 16776623; 16789641; 16796899; 16816071; 16828203; 16839401; 16845248; 16855181; 16857194; 16879222; 16879223; 16883539; 16896567; 16902162; 16914534; 16926677; 16931622; 16938111; 16945123; 16963292; 16998253; 17005586; 17006922; 17018527; 17032919; 17036337; 17044080; 17062678; 17063752; 17080225; 17100549; 17100732; 17107352; 17111197; 17119035; 17126309; 17126795; 17126831; 17160433; 17161063; 17172275; 17179821; 17182940; 17187779; 17199731; 17200772; 17201153; 17201588; 17207964; 17221326; 17230042; 17257155; 17258797; 17259369; 17263760; 17269998; 17276980; 17299841; 17309181; 17320454; 17322633; 17328891; 17351368; 17355798; 17356550; 17379280; 17388801; 17397908; 17408411; 17433639; 17456624; 17467713; 17469143; 17473573; 17473577; 17495595; 17513622; 17523079; 17540775; 17541549; 17549286; 17549383; 17555513; 17559626; 17578681; 17581326; 17593467; 17601881; 17604327; 17608581; 17616807; 17641264; 17642204; 17649957; 17656673; 17656680; 17657675; 17661167; 17671042; 17676631; 17681507; 17689411; 17689414; 17690487; 17696882; 17697137; 17698217; 17702963; 17719307; 17721610; 17721742; 17723126; 17761618; 17765897; 17786291; 17804466; 17877801; 17882266; 17884148; 17890953; 17895116; 17899094; 17903340; 17922472; 17932317; 17934860; 17949793; 17949795; 17949955; 17972336; 17975760; 17985503; 17986506; 17992643; 18023202; 18024289; 18029284; 18037477; 18045665; 18057060; 18058192; 18064331; 18075282; 18077030; 18078928; 18083357; 18096824; 18160587; 18160588; 18160589; 18160600; 18160602; 18173921; 18174166; 18180317; 18182031; 18182917; 18196271; 18208536; 18234320; 18239151; 18262228; 18263635; 18276785; 18278185; 18284606; 18285546; 18289715; 18296846; 18307986; 18318764; 18337154; 18341631; 18344023; 18358555; 18362590; 18366077; 18376309; 18381294; 18383878; 18386027; 18393255; 18423526; 18436534; 18445685; 18454324; 18459951; 18463321; 18465330; 18468424; 18469003; 18495745; 18503142; 18508114; 18511872; 18513389; 18519237; 18519558; 18524690; 18559377; 18563738; 18580060; 18597060; 18599586; 18600083; 18609532; 18614541; 18615155; 18616803; 18618228; 18619429; 18621614; 18624608; 18646302; 18658131; 18662099; 18665040; 18674955; 18683152; 18685811; 18700166; 18714537; 18720901; 18722101; 18725338; 18728123; 18768333; 18794724; 18795717; 18796547; 18797412; 18800213; 18803625; 18804848; 18809301; 18818228; 18818748; 18819934; 18820218; 18828272; 18829023; 18832570; 18835034; 18853133; 18922856; 18930220; 18931510; 18936436; 18953568; 18974388; 18974580; 18974842; 18977990; 18978303; 18983502; 19004141; 19008959; 19015166; 19016004; 19018779; 19019335; 19033264; 19037965; 19050632; 19052924; 19056482; 19061349; 19063817; 19066200; 19072566; 19080373; 19082473; 19085655; 19088796; 19110485; 19117638; 19123042; 19123477; 19127083; 19131662; 19132225; 19136619; 19147537; 19154538; 19167867; 19176991; 19193026; 19238444; 19238514; 19247692; 19263529; 19282863; 19290852; 19336886; 19350365; 19351570; 19356953; 19368854; 19370415; 19387177; 19387820; 19395327; 19401121; 19410276; 19419896; 19419975; 19420105; 19423540; 19438580; 19439404; 19443353; 19444746; 19475533; 19479237; 19483400; 19487690; 19492158; 19500510; 19501581; 19513384; 19521296; 19523975; 19526059; 19527514; 19536843; 19540572; 19553556; 19559392; 19560472; 19565516; 19574558; 19578796; 19604112; 19604604; 19608328; 19608644; 19628210; 19628666; 19636212; 19644850; 19664386; 19682239; 19691831; 19698976; 19699511; 19718071; 19718486; 19729601; 19752858; 19774387; 19776673; 19821806; 19824427; 19838007; 19838435; 19844663; 19855083; 19856137; 19857655; 19860767; 19896127; 19906129; 19909951; 19913121; 19916862; 19923980; 19924498; 19929406; 19933990; 19934566; 19942375; 19942593; 19948975; 19956635; 20005426; 20006393; 20017074; 20036902; 20039121; 20051843; 20051950; 20066125; 20074437; 20079523; 20079702; 20082208; 20107738; 20118711; 20127289; 20128871; 20133900; 20134171; 20136501; 20140262; 20142115; 20158910; 20161734; 20204407; 20207250; 20216986; 20222049; 20228065; 20236028; 20299979; 20300183; 20302034; 20334849; 20346360; 20351105; 20352162; 20353610; 20356416; 20371491; 20374070; 20385790; 20392162; 20392463; 20406964; 20425806; 20428185; 20429897; 20435362; 20438785; 20447686; 20452482; 20460339; 20470281; 20472470; 20492459; 20500107; 20508517; 20519507; 20532885; 20535834; 20536507; 20538960; 20549826; 20558613; 20567875; 20602615; 20614004; 20623540; 20624254; 20626032; 20628086; 20628624; 20630999; 20663859; 20669347; 20673868; 20686427; 20706793; 20708412; 20717043; 20724304; 20727996; 20734064; 20737565; 20740581; 20806116; 20810696; 20816667; 20818488; 20818980; 20822334; 20827781; 20838737; 20856803; 20886187; 20923324; 20926026; 20931209; 20959880; 21034162; 21037509; 21039385; 21042829; 21054877; 21070757; 21078611; 21080081; 21082259; 21122850; 21125336; 21128994; 21129210; 21135093; 21139048; 21141508; 21158116; 21175428; 21189605; 21199867; 21216681; 21240498; 21241403; 21268395; 21278057; 21280127; 21280128; 21304999; 21306344; 21311952; 21316840; 21332339; 21370208; 21373825; 21406565; 21413876; 21414238; 21450592; 21459526; 21478092; 21478212; 21490692; 21501649; 21512162; 21515439; 21524281; 21530867; 21545519; 21606492; 21624046; 21642818; 21647848; 21689370; 21697084; 21702998; 21707474; 21711960; 21719525; 21725041; 21744990; 21752301; 21761413; 21819560; 21823537; 21846428; 21849906; 21850503; 21878476; 21878751; 21885611; 21900343; 21911891; 21947232; 21968503; 21975339; 21989445; 21993838; 21996594; 22011808; 22055623; 22064653; 22088447; 22099705; 22100658; 22106856; 22108519; 22133274; 22134139; 22158046; 22171322; 22198637; 22200807; 22240314; 22258825; 22283974; 22331587; 22334677; 22354580; 22385289; 22389473; 22390401; 22410565; 22432640; 22459021; 22466984; 22467324; 22479620; 22491740; 22496752; 22503724; 22512572; 22516898; 22527222; 22552687; 22566702; 22572461; 22577291; 22578058; 22592924; 22613596; 22653645; 22736074; 22740034; 22740053; 22745374; 22747686; 22771216; 22798504; 22803111; 22809141; 22819264; 22819712; 22850480; 22882325; 22909576; 22952991; 22982001; 22984202; 22990020; 22995304; 23052060; 23052617; 23111469; 23179239; 23180602; 23184207; 23218127; 23222167; 23259783; 23280079; 23281898; 23283030; 23289804; 23291383; 23304115; 23324247; 23382992; 23429214; 23437240; 23438482; 23445116; 23457639; 23461356; 23521508; 23536951; 23541763; 23639427; 23685140; 23770264; 23790781; 23814118; 23835737; 23873179; 23898067; 23898913; 24172014; 24200683; 24297881; 24375485 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 Ensembl:ENSG00000106366 HGNC:8583 HPRD:01418 MIM:173360 Vega:OTTHUMG00000157107 SERPINE1 Bin Zhao, Yue Liu, Oliver He HEL-S-85 HNRPE1 HNRPX hnRNP-E1 hnRNP-X WEB: http://www.ncbi.nlm.nih.gov/gene PCBP1 poly(rC) binding protein 1 5093 2p13-p12 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0000398 (EC: TAS); GO_0003697 (EC: IDA, PMID: 8152927); GO_0003723 (EC: IDA, PMID: 7556077); GO_0005515 (EC: IPI, PMID: 16713569); GO_0005654 (EC: TAS); GO_0005737 (EC: IEA); GO_0008380 (EC: TAS); GO_0010467 (EC: TAS); GO_0030529 (EC: IEA); GO_0044822 (EC: IDA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 7556077; 7607214; 8152927; 8833161; 8855318; 9234743; 10373504; 10455157; 10936052; 11591653; 11790298; 12011088; 12226669; 12414943; 12431987; 12477932; 12527772; 12890803; 12933794; 12970749; 14612387; 15169918; 15246275; 15302935; 15456888; 15489334; 15514164; 15635413; 15933215; 16248985; 16341674; 16510139; 16713569; 16775011; 16964243; 17081983; 17207965; 17314511; 17332742; 17361185; 17383969; 17389360; 17451601; 17622584; 17643375; 18457437; 18511687; 18656558; 18781797; 18850631; 19056867; 19166625; 19211566; 19322201; 19471022; 19727227; 19738201; 19808671; 20020773; 20360068; 20361869; 20462248; 20519371; 20609352; 20811636; 21110914; 21139048; 21145461; 21319273; 21549307; 21575865; 21752917; 21832049; 21853274; 21890473; 21906983; 21930702; 21963094; 21987572; 21988832; 22102042; 22105485; 22118674; 22268729; 22304920; 22354994; 22365833; 22412018; 22505724; 22623428; 22673507; 22801034; 22863883; 22939629; 23000965; 23246001; 23398456; 23402259; 23438482; 23439585; 23463506; 23478261; 23602568; 23629627; 23640898; 23798571; 23862649; 23940783; 24457600 poly(rC) binding protein 1 Ensembl:ENSG00000169564 HGNC:8647 HPRD:03128 MIM:601209 Vega:OTTHUMG00000129645 PCBP1 Bin Zhao, Yue Liu, Oliver He HNRNPE2 HNRPE2 hnRNP-E2 WEB: http://www.ncbi.nlm.nih.gov/gene PCBP2 poly(rC) binding protein 2 5094 12q13.13 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000398 (EC: TAS); GO_0003677 (EC: IEA); GO_0003723 (EC: IDA, PMID: 7607214); GO_0005515 (EC: IPI, PMID: 16713569); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0008380 (EC: TAS); GO_0010467 (EC: TAS); GO_0016071 (EC: NAS, PMID: 7556077); GO_0019899 (EC: IPI, PMID: 19881509); GO_0030529 (EC: IEA); GO_0031625 (EC: IPI, PMID: 19881509); GO_0032480 (EC: TAS); GO_0043161 (EC: IMP, PMID: 19881509); GO_0044822 (EC: IDA); GO_0045087 (EC: TAS); GO_0050687 (EC: IMP, PMID: 19881509); GO_0051607 (EC: IEA) PMID: 7556077; 7607214; 8125298; 8833161; 8855318; 8871564; 9223526; 9234743; 10068686; 10373504; 10455157; 10772858; 10936052; 11747608; 12011088; 12226669; 12414943; 12477932; 12515719; 12527772; 12970749; 14612387; 14702039; 15231748; 15331611; 15489334; 16094384; 16186123; 16196087; 16341674; 16713569; 17081983; 17145707; 17183366; 17219427; 17327219; 17426136; 17526645; 17581994; 17643375; 17672918; 18029348; 18086560; 18174314; 18252259; 18457437; 18656221; 18687895; 18701464; 18781797; 18850631; 18929541; 19029303; 19211566; 19230839; 19322201; 19471022; 19738201; 19808671; 19881509; 19945132; 20000738; 20020773; 20211135; 20360068; 20946988; 21081666; 21110914; 21139048; 21145461; 21252943; 21319273; 21632751; 21723381; 21752917; 21853274; 21890473; 21906983; 21963094; 21987572; 21988832; 22022391; 22079093; 22118674; 22268729; 22365833; 22379092; 22431556; 22438951; 22505724; 22623428; 22633452; 22797925; 22939629; 22990118; 23000965; 23246001; 23438482; 23455922; 23463506; 23585479; 23629627; 23640898; 23798571; 24250222; 24457600 poly(rC) binding protein 2 Ensembl:ENSG00000197111 HGNC:8648 HPRD:03129 MIM:601210 Vega:OTTHUMG00000169439 PCBP2 Bin Zhao, Yue Liu, Oliver He PEPCK-C PEPCK1 PEPCKC WEB: http://www.ncbi.nlm.nih.gov/gene PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 20q13.31 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0000287 (EC: IDA, PMID: 11851336); GO_0004613 (EC: ISS); GO_0005525 (EC: IDA, PMID: 11851336); GO_0005737 (EC: ISS); GO_0005829 (EC: TAS); GO_0005975 (EC: TAS); GO_0006006 (EC: IMP, PMID: 14764811); GO_0006006 (EC: TAS); GO_0006094 (EC: IEA); GO_0006094 (EC: ISS); GO_0006094 (EC: TAS); GO_0006107 (EC: IEA); GO_0006475 (EC: IDA); GO_0014823 (EC: IEA); GO_0017144 (EC: TAS); GO_0019003 (EC: IEA); GO_0030145 (EC: IDA, PMID: 11851336); GO_0031406 (EC: IDA, PMID: 11851336); GO_0032868 (EC: IDA, PMID: 14764811); GO_0042593 (EC: ISS); GO_0044281 (EC: TAS); GO_0046327 (EC: ISS); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1492743; 1657985; 2993287; 8325643; 8432541; 8490617; 8547315; 11689615; 11780052; 11851336; 11997389; 12237288; 12324453; 12477932; 14744869; 14764811; 15046742; 15489334; 15951444; 16132948; 16144962; 16282543; 16341674; 16344560; 16620271; 16978381; 17192490; 17440948; 17495004; 18029348; 18460190; 18492826; 18660489; 18801732; 18830724; 18976975; 18996102; 19021757; 19056482; 19056867; 19070910; 19329064; 19578796; 19725958; 19913121; 20098747; 20134411; 20574532; 20602615; 20628086; 20682687; 20691246; 20800603; 21145461; 21152065; 21726808; 21832049; 21906983; 21988832; 22489460; 23092637; 23149075; 23300278; 23465595; 23940030 phosphoenolpyruvate carboxykinase 1 (soluble) Ensembl:ENSG00000124253 HGNC:8724 HPRD:02028 MIM:614168 Vega:OTTHUMG00000032825 PCK1 Bin Zhao, Yue Liu, Oliver He BMIQ12 NEC1 PC1 PC3 SPC3 WEB: http://www.ncbi.nlm.nih.gov/gene PCSK1 proprotein convertase subtilisin/kexin type 1 5122 5q15-q21 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0004252 (EC: IBA); GO_0004252 (EC: ISS); GO_0004252 (EC: TAS); GO_0005615 (EC: IDA, PMID: 8397508); GO_0005794 (EC: IBA); GO_0006508 (EC: TAS, PMID: 9207799); GO_0007267 (EC: TAS, PMID: 9207799); GO_0008152 (EC: TAS, PMID: 9207799); GO_0016486 (EC: TAS); GO_0030133 (EC: IEA); GO_0034774 (EC: TAS); GO_0043043 (EC: ISS); GO_0044267 (EC: TAS); GO_0050796 (EC: TAS) PMID: 1547893; 1597471; 1605851; 1765368; 2061332; 3053705; 3542996; 4368999; 7639757; 7797529; 7836407; 8163529; 8397508; 8557106; 8666140; 8916141; 8940009; 8995623; 9207799; 9213372; 9521468; 10037747; 10087454; 10391209; 10409610; 10530621; 10771309; 10931181; 11113628; 11246872; 11435430; 11720250; 11739459; 12126783; 12147786; 12147787; 12477932; 12715715; 14574455; 14614908; 14617756; 15126519; 15127203; 15807527; 16293189; 16344560; 16644867; 16928730; 17595246; 17917309; 17990211; 18096669; 18343183; 18549351; 18604207; 19034419; 19164386; 19339735; 19528091; 19628676; 19641380; 19875984; 19876004; 19913121; 20106974; 20498726; 20534142; 20571754; 20628086; 20734064; 21030982; 21720444; 21805236; 21805237; 21873549; 21935364; 22000902; 22210313; 22344219; 22552345; 22581228; 22592666; 22679642; 22737226; 23121087; 23383060; 23451278; 23775089; 23800642; 23903356; 23966867; 24140494; 24226266 proprotein convertase subtilisin/kexin type 1 Ensembl:ENSG00000175426 HGNC:8743 HPRD:01201 MIM:162150 Vega:OTTHUMG00000122089 PCSK1 Bin Zhao, Yue Liu, Oliver He PDHA PDHCE1A PHE1A WEB: http://www.ncbi.nlm.nih.gov/gene PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 5160 RP11-723P2.1 Xp22.1 20140408 9606 X protein-coding Official from a nomenclature committee GO_0004738 (EC: IDA, PMID: 19081061); GO_0004739 (EC: IEA); GO_0005739 (EC: IDA); GO_0005759 (EC: TAS); GO_0006086 (EC: IDA, PMID: 19081061); GO_0006090 (EC: TAS); GO_0006096 (EC: IEA); GO_0006099 (EC: IDA, PMID: 19081061); GO_0010510 (EC: TAS); GO_0044237 (EC: TAS); GO_0044281 (EC: TAS); GO_0045254 (EC: IDA, PMID: 19081061) PMID: 1293379; 1301207; 1338114; 1551669; 1907799; 1909401; 2227443; 2377599; 2537010; 2737678; 2745444; 2748588; 2828359; 3034892; 3422424; 7273846; 7545958; 7573035; 7757088; 7782287; 7853374; 7864652; 7887409; 7967473; 8032855; 8125298; 8199595; 8498846; 8504306; 8664900; 8844217; 9003499; 9029794; 9671272; 9686362; 9799265; 10077682; 10679936; 11485553; 11486000; 12477932; 12651851; 12676647; 14638692; 14708897; 15302935; 15489334; 15861126; 16169070; 16196087; 16344560; 16713755; 16967364; 17065338; 17081983; 17353931; 17947500; 17957032; 18023225; 18398624; 19081061; 19517265; 19586787; 19615732; 20002461; 20562859; 20958858; 21139048; 21145461; 21470495; 21723463; 21809123; 21852536; 21890473; 21895644; 21914562; 21963094; 22142326; 22586326; 22623428; 22750801; 22863883; 22939629; 23798571; 23842279 pyruvate dehydrogenase (lipoamide) alpha 1 Ensembl:ENSG00000131828 HGNC:8806 HPRD:02420 MIM:300502 Vega:OTTHUMG00000021224 PDHA1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene PDK1 pyruvate dehydrogenase kinase, isozyme 1 5163 2q31.1 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0004672 (EC: IDA, PMID: 17683942); GO_0004674 (EC: IEA); GO_0004740 (EC: IDA, PMID: 7499431); GO_0004740 (EC: IMP); GO_0005515 (EC: IPI, PMID: 17110931); GO_0005524 (EC: IEA); GO_0005739 (EC: TAS, PMID: 7499431); GO_0005759 (EC: TAS); GO_0005967 (EC: IEA); GO_0006006 (EC: IEA); GO_0006090 (EC: TAS); GO_0006468 (EC: IDA, PMID: 17683942); GO_0006468 (EC: IMP); GO_0008283 (EC: IMP, PMID: 18541534); GO_0008631 (EC: IMP, PMID: 18541534); GO_0010510 (EC: TAS); GO_0010906 (EC: IMP, PMID: 18541534); GO_0044237 (EC: TAS); GO_0044281 (EC: TAS); GO_0097411 (EC: IMP) PMID: 7499431; 7864652; 10567431; 10753910; 11279232; 11485553; 11486000; 11733037; 11889038; 11978179; 12150926; 12477932; 12573248; 12676647; 14702039; 14718574; 14966024; 15489334; 15591305; 15678105; 16344560; 16517405; 17110931; 17314099; 17683942; 17785433; 18003900; 18541534; 18542064; 18954447; 19010391; 20415663; 20416077; 20877624; 21775285; 21900206; 22347420; 22623531; 22704111; 22948140; 23135628; 23300259; 24044887 pyruvate dehydrogenase kinase, isozyme 1 PDK1 Bin Zhao, Yue Liu, Oliver He GSD7 PFK-1 PFK1 PFKA PFKX WEB: http://www.ncbi.nlm.nih.gov/gene PFKM phosphofructokinase, muscle 5213 12q13.3 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0003872 (EC: IDA, PMID: 6444721); GO_0003872 (EC: IMP, PMID: 6444532); GO_0003872 (EC: ISS); GO_0005515 (EC: IPI, PMID: 12649290); GO_0005524 (EC: IDA, PMID: 8780720); GO_0005829 (EC: TAS); GO_0005945 (EC: IDA, PMID: 6444532); GO_0005975 (EC: TAS); GO_0006002 (EC: IDA, PMID: 6444721); GO_0006002 (EC: IMP, PMID: 6444532); GO_0006006 (EC: TAS); GO_0006096 (EC: IEA); GO_0006096 (EC: IMP, PMID: 6444532); GO_0006096 (EC: TAS); GO_0008022 (EC: IPI, PMID: 12649290); GO_0016324 (EC: IDA, PMID: 12649290); GO_0019900 (EC: IPI, PMID: 6444721); GO_0032024 (EC: IEA); GO_0042593 (EC: IEA); GO_0042802 (EC: IPI, PMID: 6444721); GO_0044281 (EC: TAS); GO_0046716 (EC: IMP, PMID: 6444532); GO_0046835 (EC: IDA, PMID: 6444721); GO_0046835 (EC: IMP, PMID: 6444532); GO_0046835 (EC: ISS); GO_0046872 (EC: IEA); GO_0051259 (EC: IDA, PMID: 6444721); GO_0070061 (EC: IDA, PMID: 8780720) PMID: 125160; 156693; 1833270; 2140567; 2140573; 2526044; 2526045; 2822475; 6444532; 6444721; 6459054; 7479776; 7513946; 7550225; 7825568; 8444874; 8661033; 8780720; 8889548; 8889589; 9252390; 9389749; 9443500; 10187848; 12432079; 12477932; 12649290; 14760703; 15020257; 15489334; 16344560; 17544406; 17549794; 18029348; 18624398; 18781797; 18854154; 18996102; 19019082; 19165527; 19394292; 20379614; 20483646; 20602615; 20800603; 20849852; 21124851; 21139048; 21145461; 21573193; 21890473; 21906983; 21963094; 21988832; 22133655; 22268729; 22474333; 22863883; 22939629; 22995305; 23088713; 24211586 phosphofructokinase, muscle Ensembl:ENSG00000152556 HGNC:8877 HPRD:01988 MIM:610681 Vega:OTTHUMG00000169898 PFKM Bin Zhao, Yue Liu, Oliver He BGGI GGTI WEB: http://www.ncbi.nlm.nih.gov/gene PGGT1B protein geranylgeranyltransferase type I, beta subunit 5229 5q22.3 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0004661 (EC: IDA, PMID: 16893176); GO_0004662 (EC: ISS); GO_0005953 (EC: IDA, PMID: 16893176); GO_0008270 (EC: ISS); GO_0008284 (EC: IEA); GO_0018344 (EC: IDA, PMID: 16893176); GO_0034097 (EC: IEA); GO_0045787 (EC: IEA); GO_0051771 (EC: IEA) PMID: 1400319; 7713879; 8106351; 11076863; 12477932; 14598891; 15451670; 16344560; 16893176; 19667218; 20403997; 20446922; 21906983; 22160308; 22632162; 22863883; 23475391 protein geranylgeranyltransferase type I, beta subunit Ensembl:ENSG00000164219 HGNC:8895 HPRD:03612 MIM:602031 Vega:OTTHUMG00000128893 PGGT1B Bin Zhao, Yue Liu, Oliver He HEL-S-68p MIG10 PGKA WEB: http://www.ncbi.nlm.nih.gov/gene PGK1 phosphoglycerate kinase 1 5230 RP4-570L12.1 Xq13.3 20140408 9606 X protein-coding Official from a nomenclature committee GO_0004618 (EC: EXP); GO_0004618 (EC: ISS); GO_0005515 (EC: IPI); GO_0005524 (EC: ISS); GO_0005829 (EC: TAS); GO_0005975 (EC: TAS); GO_0006006 (EC: TAS); GO_0006094 (EC: TAS); GO_0006096 (EC: IEA); GO_0006096 (EC: TAS); GO_0016310 (EC: ISS); GO_0030855 (EC: IEP); GO_0044281 (EC: TAS); GO_0070062 (EC: IDA, PMID: 11487543) PMID: 1533225; 1547346; 1586722; 1602151; 1837552; 2001457; 2324090; 2347494; 2814502; 2995995; 3453121; 6099325; 6188151; 6933565; 6941312; 7391027; 7391028; 7440217; 7892275; 8043870; 8075252; 8089148; 8122886; 8615693; 8673469; 8889548; 9023984; 9075577; 9744480; 10720297; 11130727; 11487543; 11745195; 12080078; 12174867; 12477932; 12488440; 12869554; 14733918; 14764427; 15053920; 15161933; 15255553; 15489334; 15592455; 15952740; 16009940; 16196087; 16236267; 16263121; 16363799; 16567715; 17043677; 17081983; 17148452; 17565005; 17661373; 18039033; 18096512; 18288812; 18453750; 18540639; 18603805; 18781797; 19110265; 19135240; 19688824; 19738201; 19778949; 19854185; 20000738; 20068185; 20360068; 20391533; 20562859; 20849852; 21081666; 21110914; 21139048; 21145461; 21319273; 21349853; 21505655; 21549683; 21565611; 21780947; 21853274; 21890473; 21906983; 21963094; 22053931; 22079093; 22145905; 22348148; 22505724; 22586326; 22619369; 22742733; 22939629; 23000965; 23077236; 23130662; 23336698; 23684636; 23703321; 23727790; 23824909; 23862649; 24284928; 24376734 phosphoglycerate kinase 1 Ensembl:ENSG00000102144 HGNC:8896 HPRD:02412 MIM:311800 PGK1 Bin Zhao, Yue Liu, Oliver He HEL-S-272 PGKB PGKPS dJ417L20.2 WEB: http://www.ncbi.nlm.nih.gov/gene PGK2 phosphoglycerate kinase 2 5232 6p12.3 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0004618 (EC: ISS); GO_0004618 (EC: NAS, PMID: 3453121); GO_0005524 (EC: ISS); GO_0005737 (EC: IEA); GO_0006096 (EC: IEA); GO_0006096 (EC: NAS, PMID: 3453121); GO_0016310 (EC: ISS); GO_0016310 (EC: NAS, PMID: 3453121) PMID: 1278465; 2027764; 2032717; 2156237; 2767684; 2813402; 2886978; 2987238; 3453121; 3839763; 6328504; 6873461; 9023984; 10330089; 12477932; 14574404; 15489334; 16196087; 16344560; 18976975; 19333399; 20459611; 21853274; 21890473; 21906983; 21963094; 22505724; 23000965 phosphoglycerate kinase 2 Ensembl:ENSG00000170950 HGNC:8898 HPRD:01393 MIM:172270 Vega:OTTHUMG00000014824 PGK2 Bin Zhao, Yue Liu, Oliver He AGM1 PAGM PGM 3 WEB: http://www.ncbi.nlm.nih.gov/gene PGM3 phosphoglucomutase 3 5238 6q14.1-q15 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000287 (EC: IEA); GO_0004610 (EC: IDA, PMID: 11004509); GO_0004614 (EC: IEA); GO_0005575 (EC: ND); GO_0005829 (EC: IBA); GO_0005829 (EC: TAS); GO_0006041 (EC: NAS, PMID: 11004509); GO_0006048 (EC: IBA); GO_0006048 (EC: IEA); GO_0006048 (EC: TAS); GO_0006488 (EC: TAS); GO_0007283 (EC: IEA); GO_0009790 (EC: IEA); GO_0018279 (EC: TAS); GO_0019255 (EC: IEA); GO_0030097 (EC: IBA); GO_0043687 (EC: TAS); GO_0044267 (EC: TAS) PMID: 203189; 468082; 508567; 6461922; 8125298; 10721701; 11004509; 12174217; 12477932; 12752494; 14574404; 14702039; 15489334; 16344560; 20221814; 20800603; 21139048; 21145461; 21159204; 21832049; 21890473; 21906983; 21963094; 23000965; 23042605; 23824909 phosphoglucomutase 3 Ensembl:ENSG00000013375 HGNC:8907 HPRD:01390 MIM:172100 Vega:OTTHUMG00000015110 PGM3 Bin Zhao, Yue Liu, Oliver He PI12 neuroserpin WEB: http://www.ncbi.nlm.nih.gov/gene SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 5274 3q26.1 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0004867 (EC: IBA); GO_0005615 (EC: IEA); GO_0007417 (EC: TAS, PMID: 9070919); GO_0007422 (EC: TAS, PMID: 9070919); GO_0008219 (EC: IEA); GO_0010951 (EC: IBA); GO_0030155 (EC: IEA); GO_0030162 (EC: IBA) PMID: 9070919; 9407089; 10517635; 10992299; 11880376; 12103288; 12228252; 12354288; 12477932; 14983220; 15090543; 15269833; 15291813; 15489334; 15664988; 16344560; 16849336; 17212813; 17606885; 17961231; 18029348; 18051703; 18391951; 18591508; 19222708; 19265707; 19423540; 19423713; 20406964; 20438785; 20691191; 21081089; 21174006; 21487809; 21507957; 21569344; 21961602; 23534349; 24172014 serpin peptidase inhibitor, clade I (neuroserpin), member 1 Ensembl:ENSG00000163536 HGNC:8943 HPRD:03901 MIM:602445 Vega:OTTHUMG00000158450 SERPINI1 Bin Zhao, Yue Liu, Oliver He PLA2 PLA2A PPLA2 WEB: http://www.ncbi.nlm.nih.gov/gene PLA2G1B phospholipase A2, group IB (pancreas) 5319 12q24.31 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000187 (EC: ISS, PMID: 15528384); GO_0002446 (EC: ISS, PMID: 16005851); GO_0004623 (EC: IDA, PMID: 1918029); GO_0005102 (EC: IDA, PMID: 1918029); GO_0005102 (EC: IPI, PMID: 7721806); GO_0005509 (EC: IDA, PMID: 7060561); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 7060561); GO_0006633 (EC: IDA, PMID: 1918029); GO_0006644 (EC: TAS); GO_0006654 (EC: TAS); GO_0007015 (EC: TAS, PMID: 9886417); GO_0007165 (EC: TAS, PMID: 9886417); GO_0009986 (EC: IDA, PMID: 1918029); GO_0010524 (EC: ISS, PMID: 15528384); GO_0015758 (EC: ISS, PMID: 1918029); GO_0019370 (EC: ISS, PMID: 16005851); GO_0030141 (EC: IEA); GO_0030593 (EC: ISS, PMID: 16005851); GO_0032052 (EC: ISS, PMID: 7060561); GO_0032431 (EC: TAS, PMID: 17981679); GO_0032637 (EC: ISS, PMID: 15528384); GO_0032869 (EC: ISS, PMID: 1918029); GO_0035556 (EC: ISS, PMID: 15528384); GO_0036148 (EC: TAS); GO_0036149 (EC: TAS); GO_0036150 (EC: TAS); GO_0036151 (EC: TAS); GO_0036152 (EC: TAS); GO_0044240 (EC: IDA, PMID: 7060561); GO_0044281 (EC: TAS); GO_0045740 (EC: IDA, PMID: 1918029); GO_0045944 (EC: ISS, PMID: 15528384); GO_0046470 (EC: IDA, PMID: 7060561); GO_0046474 (EC: TAS); GO_0047498 (EC: IDA, PMID: 7060561); GO_0048146 (EC: IC, PMID: 1918029); GO_0050482 (EC: TAS, PMID: 12423354); GO_0050714 (EC: TAS, PMID: 17981679); GO_0050778 (EC: ISS, PMID: 16005851); GO_0051092 (EC: ISS, PMID: 15528384) PMID: 1918029; 2052621; 3028739; 6349696; 6477929; 7060561; 7584826; 7590434; 7721806; 8175726; 8300559; 8358438; 9188469; 9377118; 9745929; 9847074; 9848887; 9886417; 10509674; 10551547; 10735945; 10873103; 10905638; 10964913; 11025364; 11353443; 11510783; 11807183; 11851982; 12423354; 12477932; 12759552; 14557262; 14998370; 15220446; 15489334; 15528384; 15736947; 16005851; 16391564; 16392040; 16495221; 16541075; 16567514; 17065600; 17223797; 17434532; 17470210; 17488462; 17981679; 18212756; 18492292; 18636547; 19297324; 19913121; 20536387; 20628086; 21988832; 22528125; 22680611 phospholipase A2, group IB (pancreas) Ensembl:ENSG00000170890 HGNC:9030 HPRD:01396 MIM:172410 Vega:OTTHUMG00000169343 PLA2G1B Bin Zhao, Yue Liu, Oliver He PLA2G4 cPLA2-alpha WEB: http://www.ncbi.nlm.nih.gov/gene PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 5321 1q25 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0004622 (EC: IEA); GO_0004623 (EC: IDA, PMID: 8702602); GO_0004623 (EC: NAS, PMID: 8381049); GO_0004623 (EC: TAS); GO_0005509 (EC: IDA, PMID: 9430701); GO_0005544 (EC: IDA, PMID: 9665851); GO_0005737 (EC: IDA); GO_0005743 (EC: TAS); GO_0005789 (EC: TAS); GO_0005794 (EC: IEA); GO_0005829 (EC: NAS, PMID: 8381049); GO_0005829 (EC: TAS); GO_0006644 (EC: TAS); GO_0006654 (EC: TAS); GO_0006663 (EC: NAS, PMID: 9430701); GO_0006690 (EC: NAS, PMID: 9430701); GO_0007596 (EC: TAS); GO_0009395 (EC: IEA); GO_0016023 (EC: IEA); GO_0019369 (EC: TAS); GO_0030168 (EC: TAS); GO_0035965 (EC: TAS); GO_0036148 (EC: TAS); GO_0036149 (EC: TAS); GO_0036150 (EC: TAS); GO_0036151 (EC: TAS); GO_0036152 (EC: TAS); GO_0042127 (EC: IEA); GO_0044281 (EC: TAS); GO_0046456 (EC: IEA); GO_0046474 (EC: TAS); GO_0047498 (EC: EXP); GO_0050482 (EC: IEA); GO_0071236 (EC: IEA) PMID: 1869522; 1904318; 7782073; 7800505; 7862535; 7999086; 8083230; 8175726; 8381049; 8612580; 8636128; 8702602; 8910365; 9239738; 9377118; 9430701; 9468497; 9665851; 9745929; 9875225; 10085124; 10319815; 10625659; 10978317; 11416127; 12048163; 12050227; 12124392; 12414998; 12477932; 12765847; 12885780; 14609334; 14686920; 14726390; 14769798; 14963030; 15007070; 15041036; 15118355; 15259375; 15276701; 15294900; 15302935; 15305015; 15318030; 15331599; 15358156; 15475363; 15489334; 15789617; 15862967; 15975962; 16181776; 16221889; 16344560; 16407173; 16409471; 16462602; 16585943; 16603549; 16710414; 16754327; 16829784; 16963226; 16964243; 17081983; 17178883; 17344094; 17417066; 17460547; 17629734; 17672871; 17685590; 17873281; 17901074; 17971499; 17976189; 18029351; 18280113; 18388244; 18451993; 18471798; 18502815; 18562188; 18566601; 18583979; 18632668; 18665843; 18686860; 18781797; 18818748; 18840708; 19019335; 19091957; 19176526; 19237603; 19280714; 19336370; 19401382; 19450127; 19527514; 19560328; 19625654; 19632995; 19675210; 19717620; 19753100; 19778898; 19795129; 19913121; 20034614; 20056178; 20066429; 20069553; 20112044; 20140262; 20203101; 20211985; 20227521; 20351714; 20379614; 20392485; 20435073; 20464283; 20478385; 20628086; 20635443; 20643646; 20705608; 20802406; 20808133; 21097525; 21127289; 21139048; 21148506; 21185392; 21198294; 21247147; 21268080; 21315000; 21478406; 21536681; 21771656; 21825068; 21862584; 21896865; 21906983; 21963094; 22003202; 22138395; 22274867; 22378731; 22398721; 22456504; 22648535; 22728329; 22863883; 22895089; 22911431; 22939629; 22949513; 23043861; 23219238; 23268370; 23307260; 23801329 phospholipase A2, group IVA (cytosolic, calcium-dependent) Ensembl:ENSG00000116711 HGNC:9035 HPRD:08986 MIM:600522 Vega:OTTHUMG00000035512 PLA2G4A Bin Zhao, Yue Liu, Oliver He T-PA TPA WEB: http://www.ncbi.nlm.nih.gov/gene PLAT plasminogen activator, tissue 5327 8p12 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0001666 (EC: IEA); GO_0004252 (EC: IDA, PMID: 1695900); GO_0004252 (EC: TAS); GO_0005515 (EC: IPI, PMID: 10340997); GO_0005576 (EC: TAS); GO_0005615 (EC: IEA); GO_0005737 (EC: IDA, PMID: 1632457); GO_0006464 (EC: TAS, PMID: 3087818); GO_0006508 (EC: TAS, PMID: 3087818); GO_0007596 (EC: TAS); GO_0009986 (EC: IDA, PMID: 1632457); GO_0014909 (EC: IEA); GO_0030141 (EC: IEA); GO_0031012 (EC: IDA, Qualifier: NOT, PMID: 1632457); GO_0031639 (EC: IDA, PMID: 12694198); GO_0035249 (EC: IEA); GO_0042730 (EC: TAS); GO_0043434 (EC: IEA); GO_0045177 (EC: IEA); GO_0045202 (EC: IEA); GO_0045861 (EC: IDA, PMID: 1695900); GO_0048008 (EC: IEA); GO_0048167 (EC: IEA); GO_0051384 (EC: IEA); GO_0051591 (EC: IEA); GO_0060279 (EC: IEA); GO_0070062 (EC: IDA) PMID: 1301152; 1310033; 1368681; 1502153; 1602484; 1632457; 1645336; 1695900; 1762144; 1783394; 1900431; 1901789; 1909331; 1930175; 2107490; 2107528; 2110366; 2496749; 2503541; 2513186; 2551064; 2558718; 2745554; 2838384; 2962641; 3009482; 3087818; 3088041; 3090045; 3090401; 3103680; 3126346; 3133640; 3161893; 3896853; 6089198; 6337343; 6433976; 6538514; 6538515; 6572897; 6682760; 7582899; 7586269; 7721771; 7876253; 8360181; 8366113; 8508955; 8533091; 8607113; 8613982; 9268299; 9305622; 9359841; 9434908; 9988531; 10340997; 10543954; 10632583; 10956663; 11170397; 11371191; 11384978; 11385207; 11450845; 11507973; 11734662; 11734664; 11816707; 11848437; 11858184; 11864703; 11864708; 11928812; 11928826; 11963567; 11978811; 11986218; 11988309; 12023848; 12090757; 12123488; 12167592; 12228252; 12354288; 12390834; 12445472; 12468550; 12468767; 12477932; 12484521; 12524082; 12544724; 12544772; 12589088; 12643326; 12694198; 12719777; 12719778; 12726991; 12727218; 12794725; 12891381; 12913003; 12941043; 14500731; 14529669; 14592829; 14608053; 14630788; 14697941; 14746139; 14759258; 14983221; 15016824; 15031453; 15080889; 15109703; 15116264; 15119966; 15140132; 15207811; 15269833; 15448144; 15466927; 15489334; 15541709; 15542697; 15550028; 15629242; 15652516; 15721275; 15846799; 15861134; 15869598; 15916851; 15976969; 16015279; 16037259; 16113755; 16179568; 16248996; 16320350; 16344560; 16356191; 16369808; 16385091; 16410064; 16466010; 16614319; 16706993; 16733850; 16828203; 16836660; 16839347; 16879221; 16953275; 17003923; 17064755; 17145060; 17151781; 17207964; 17257155; 17264956; 17287634; 17320454; 17408411; 17419735; 17458906; 17473573; 17608581; 17636064; 17649957; 17661167; 17681507; 17689414; 17934860; 17986506; 18023202; 18029284; 18029348; 18037995; 18057060; 18194423; 18202522; 18289715; 18321860; 18331597; 18419748; 18449420; 18468424; 18472001; 18541262; 18574075; 18629628; 18647223; 18662099; 18690354; 18714030; 18720901; 18818748; 18922856; 18945481; 18953568; 18974842; 18977990; 18983502; 19019335; 19061349; 19085655; 19088796; 19116134; 19171142; 19176991; 19217651; 19222708; 19238444; 19257978; 19290852; 19356953; 19483400; 19492158; 19513384; 19526059; 19527514; 19538480; 19578796; 19698976; 19718485; 19730683; 19874473; 19913121; 19929406; 19948975; 20097831; 20140262; 20217999; 20218002; 20409678; 20445443; 20447686; 20452482; 20472470; 20500107; 20508517; 20559098; 20628086; 20628624; 20673868; 20686427; 20811636; 20838737; 20845058; 21034162; 21082259; 21158116; 21174002; 21282301; 21304999; 21314733; 21392255; 21414238; 21437359; 21501649; 21576385; 21791417; 21848677; 21868730; 21898905; 21900343; 22027013; 22035541; 22037173; 22104068; 22178875; 22187433; 22240314; 22577291; 22610100; 22771216; 22778398; 22787391; 22957978; 23082219; 23117722; 23118500; 23161549; 23306318; 23317922; 23326456; 23423137; 23570848; 23788583; 23939410; 23959729; 24129569; 24145699 plasminogen activator, tissue Ensembl:ENSG00000104368 HGNC:9051 HPRD:01419 MIM:173370 Vega:OTTHUMG00000164072 PLAT Bin Zhao, Yue Liu, Oliver He ATF BDPLT5 QPD UPA URK u-PA WEB: http://www.ncbi.nlm.nih.gov/gene PLAU plasminogen activator, urokinase 5328 RP11-417O11.1 10q22.2 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0001666 (EC: IEA); GO_0004252 (EC: TAS); GO_0005515 (EC: IPI, PMID: 10340997); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 18835034); GO_0005886 (EC: TAS); GO_0006508 (EC: TAS, PMID: 6589620); GO_0006935 (EC: TAS, PMID: 10749881); GO_0007165 (EC: TAS, PMID: 10749881); GO_0007596 (EC: TAS); GO_0009986 (EC: IDA, PMID: 18835034); GO_0010469 (EC: IDA, PMID: 8837777); GO_0014909 (EC: IEA); GO_0014910 (EC: IDA, PMID: 8837777); GO_0033628 (EC: IDA, PMID: 8837777); GO_0042127 (EC: IEA); GO_0042730 (EC: TAS); GO_0061041 (EC: IC, PMID: 8837777); GO_2000097 (EC: IDA, PMID: 8837777) PMID: 134998; 1327118; 1334458; 1499567; 1551416; 1900515; 2023947; 2161846; 2166055; 2415429; 2536903; 2544876; 2551064; 2752144; 2829380; 2987867; 3023326; 3031025; 3090045; 3501295; 3840278; 3888571; 3920216; 3933505; 4226004; 6589620; 6749491; 6754569; 6754572; 7548163; 7559792; 7592875; 7721771; 7867716; 8033079; 8107091; 8227186; 8270642; 8344937; 8388810; 8428004; 8591045; 8652631; 8676469; 8837777; 8895530; 9065988; 9143604; 9151681; 9184208; 9194591; 9365930; 9516128; 9566979; 9680361; 9766559; 9824347; 10221568; 10340997; 10361124; 10362070; 10402467; 10505055; 10636902; 10749881; 10788498; 10805774; 10962009; 10996659; 11023511; 11266465; 11384978; 11394884; 11501527; 11751384; 11805108; 11827968; 11858184; 11876553; 11880102; 11906036; 11928806; 11928807; 11928809; 11928812; 11928816; 11928818; 11930938; 11956327; 12008951; 12023847; 12041678; 12084931; 12115506; 12149463; 12152683; 12161038; 12167592; 12174885; 12183060; 12218297; 12236587; 12353084; 12377770; 12393547; 12430175; 12477728; 12477932; 12529357; 12556966; 12574820; 12576295; 12642587; 12684636; 12704669; 12708473; 12719778; 12719789; 12736046; 12743986; 12754271; 12764090; 12771144; 12773490; 12832381; 12881310; 12883725; 12898287; 12926141; 12930304; 12941043; 12960238; 14507113; 14517288; 14531820; 14534291; 14597629; 14644829; 14681909; 14696115; 14704150; 14744782; 14747469; 14769799; 14982725; 14983219; 14983227; 15067375; 15083890; 15149885; 15210852; 15217951; 15231498; 15243126; 15262029; 15326109; 15356878; 15371454; 15375521; 15489334; 15494526; 15515049; 15558716; 15615772; 15616835; 15629242; 15646834; 15653692; 15728176; 15750768; 15831288; 15849510; 15854129; 15868845; 15880258; 15881651; 15885322; 15886816; 15927351; 15937335; 15944400; 15988036; 15996887; 16008557; 16077991; 16102112; 16113755; 16127174; 16236890; 16267271; 16385451; 16456079; 16459332; 16461772; 16504015; 16509805; 16525631; 16547007; 16601839; 16604464; 16632475; 16685436; 16685447; 16728704; 16761300; 16794252; 16806969; 16807059; 16825285; 16825821; 16836076; 16855359; 16858643; 16879932; 16908524; 16949925; 16967469; 17013094; 17029796; 17080225; 17083312; 17159381; 17174555; 17187779; 17192053; 17203175; 17203182; 17222367; 17233842; 17240317; 17258797; 17264329; 17299802; 17299841; 17327908; 17331567; 17344041; 17355798; 17363771; 17458906; 17523079; 17532189; 17545513; 17548050; 17549401; 17559626; 17581316; 17601350; 17611702; 17634019; 17638874; 17649957; 17654528; 17657740; 17661167; 17681345; 17709546; 17877801; 17880283; 17921261; 17923479; 17934860; 17949787; 17974965; 17986506; 17994220; 18048089; 18053985; 18076013; 18177545; 18193533; 18196271; 18202522; 18208536; 18237545; 18239069; 18240004; 18257282; 18321763; 18331597; 18337556; 18355442; 18362146; 18376307; 18376415; 18390474; 18436804; 18439850; 18466392; 18478929; 18491991; 18511987; 18519237; 18570153; 18599586; 18600101; 18691743; 18714186; 18788551; 18824154; 18835034; 18940913; 18949356; 18954937; 18977241; 18988861; 18997817; 19020551; 19029443; 19088796; 19097143; 19101688; 19102416; 19115132; 19117638; 19123477; 19132247; 19133257; 19147749; 19157142; 19176991; 19177205; 19232508; 19272641; 19298527; 19394555; 19403319; 19436306; 19475533; 19490101; 19497963; 19513384; 19526059; 19536843; 19546228; 19616049; 19693769; 19701247; 19703758; 19723042; 19729488; 19730683; 19735728; 19740518; 19776673; 19826838; 19845941; 19889475; 19903858; 19913121; 20007542; 20015050; 20036101; 20039121; 20043086; 20051950; 20052287; 20097831; 20198323; 20204407; 20301340; 20337595; 20369484; 20403162; 20445443; 20452482; 20518747; 20565774; 20584616; 20628086; 20628624; 20645833; 20651370; 20673868; 20693403; 20708412; 20740581; 20805979; 20931209; 20937265; 21071923; 21076612; 21104439; 21106716; 21163940; 21174062; 21181094; 21199867; 21219832; 21242962; 21316840; 21426933; 21567400; 21574189; 21627387; 21669207; 21670079; 21709151; 21711960; 21744990; 21761413; 21798735; 21819230; 21833477; 21858104; 21913037; 21965736; 21988832; 21989445; 22004682; 22035541; 22102275; 22166006; 22177802; 22199285; 22280367; 22291969; 22294827; 22354580; 22467324; 22470492; 22575880; 22684547; 22702340; 22707264; 22797075; 22797919; 22906080; 22927998; 22986534; 22994764; 23059760; 23064953; 23169000; 23322578; 23350235; 23392805; 23441133; 23532423; 23536772; 23615713; 23628797; 23661254; 23661758; 23848154; 23864708; 23898067; 24479343 plasminogen activator, urokinase Ensembl:ENSG00000122861 HGNC:9052 HPRD:01883 MIM:191840 Vega:OTTHUMG00000018494 PLAU Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene PLG plasminogen 5340 RP1-81D8.1 6q26 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0002576 (EC: TAS); GO_0004252 (EC: IDA, PMID: 14699093); GO_0005515 (EC: IPI, PMID: 10077593); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 6216475); GO_0005886 (EC: TAS); GO_0007596 (EC: IMP, PMID: 1986355); GO_0007596 (EC: TAS); GO_0008285 (EC: TAS, PMID: 8910613); GO_0009986 (EC: IDA, PMID: 14699093); GO_0010812 (EC: IDA, PMID: 14699093); GO_0019904 (EC: IPI, PMID: 9786936); GO_0022617 (EC: IDA, PMID: 14699093); GO_0022617 (EC: TAS); GO_0030168 (EC: TAS); GO_0030198 (EC: TAS); GO_0031093 (EC: TAS); GO_0031232 (EC: IDA, PMID: 14699093); GO_0034185 (EC: IPI, PMID: 16480936); GO_0042246 (EC: IEA); GO_0042730 (EC: TAS); GO_0044267 (EC: TAS); GO_0045445 (EC: IEA); GO_0046716 (EC: IEA); GO_0048771 (EC: IEA); GO_0051603 (EC: IEA); GO_0051918 (EC: IDA, PMID: 14726399); GO_0051919 (EC: IDA, PMID: 6438154); GO_0060707 (EC: IEA); GO_0060716 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19199708); GO_0071674 (EC: IEA); GO_0072562 (EC: IDA); GO_2000048 (EC: TAS, PMID: 17203182) PMID: 122932; 126863; 134998; 142009; 146197; 158022; 479158; 659588; 1427790; 1657148; 1657149; 1909331; 1939207; 1986355; 2065054; 2157850; 2318848; 2437112; 2522013; 2745554; 2829380; 2962191; 2962641; 3030813; 3334852; 3356193; 3920216; 4226004; 4240117; 4694729; 5475635; 6094526; 6148961; 6216475; 6238949; 6438154; 6582496; 6838832; 6919539; 6980881; 7525077; 7538844; 7548163; 7586586; 7814888; 7982919; 8054447; 8162705; 8181475; 8181476; 8360181; 8392398; 8460120; 8478593; 8555184; 8611560; 8612605; 8652577; 8843739; 8910613; 9020112; 9054441; 9102221; 9102401; 9201958; 9234243; 9242524; 9305949; 9337997; 9360944; 9375744; 9428707; 9490681; 9521645; 9548733; 9596664; 9688635; 9737862; 9783753; 9786936; 9834305; 9858247; 10069369; 10077593; 10215610; 10218588; 10233898; 10512713; 10604721; 10625689; 10656799; 10700393; 10889192; 10928473; 10956663; 10964919; 10974350; 10978167; 11027681; 11100730; 11113116; 11169399; 11257124; 11263499; 11342539; 11350170; 11371191; 11438139; 11729324; 11888684; 11928826; 11939791; 12016220; 12036889; 12054798; 12080056; 12093796; 12189145; 12192005; 12228252; 12406896; 12456874; 12477932; 12604689; 12646571; 12692411; 12697748; 12700073; 12736244; 12871329; 12876630; 14574404; 14678821; 14699093; 14719094; 14726399; 14739127; 14739293; 14764098; 14769799; 15090462; 15099286; 15207811; 15211511; 15215240; 15220341; 15299951; 15321992; 15333838; 15489334; 15501816; 15529749; 15609351; 15613921; 15642732; 15677446; 15746964; 15911629; 16043488; 16087677; 16097950; 16229836; 16319056; 16478887; 16480936; 16601838; 16790522; 16828203; 17115186; 17200769; 17203182; 17206383; 17272502; 17379720; 17545513; 17606760; 17616171; 17653767; 17656680; 17890952; 17927806; 17976375; 17978577; 18039838; 18070889; 18160581; 18163891; 18223261; 18279394; 18289715; 18310038; 18329389; 18331597; 18366077; 18392331; 18566672; 18568768; 18624398; 18658146; 18667578; 18685433; 18714035; 18981180; 18983515; 19074676; 19158842; 19199708; 19308255; 19363026; 19465692; 19574304; 19712047; 19800007; 19801674; 19821587; 19850343; 19913121; 20056908; 20095998; 20112045; 20140262; 20143645; 20152941; 20346360; 20346413; 20553606; 20565259; 20617841; 20628086; 20655859; 20702651; 20709033; 20726765; 21072208; 21174000; 21236472; 21300353; 21316746; 21464960; 21467042; 21510941; 21543325; 21680799; 21755014; 21787393; 21802507; 21832858; 21900290; 21988832; 21998162; 22027013; 22079981; 22124123; 22147698; 22187433; 22197896; 22287006; 22507544; 22518846; 22619171; 22641690; 22677171; 22685231; 22732096; 22773346; 22832192; 22987920; 22996753; 23071278; 23071827; 23103380; 23118497; 23140098; 23150713; 23341464; 23449787; 23481605; 23576799; 23583624; 23645683; 23699598; 23702659; 23721211; 23853591; 24029428; 24457600; 24605649 plasminogen PLG Bin Zhao, Yue Liu, Oliver He GPM6C HLD1 MMPL PLP PLP/DM20 PMD SPG2 WEB: http://www.ncbi.nlm.nih.gov/gene PLP1 proteolipid protein 1 5354 GHc-698D2.1 Xq22 20140408 9606 X protein-coding Official from a nomenclature committee GO_0005198 (EC: TAS, PMID: 2479017); GO_0005886 (EC: IDA); GO_0007229 (EC: IEA); GO_0007268 (EC: TAS, PMID: 2479017); GO_0008219 (EC: IEA); GO_0008366 (EC: TAS, PMID: 2479017); GO_0010628 (EC: IEA); GO_0016021 (EC: IEA); GO_0019911 (EC: IEA); GO_0021762 (EC: IEP); GO_0022010 (EC: IEA); GO_0042759 (EC: IEA); GO_0043209 (EC: IEA); GO_0048469 (EC: IEA) PMID: 1376966; 1384324; 1707231; 1708672; 1711121; 1715570; 2441695; 2449536; 2467009; 2479017; 2480601; 2773936; 3457761; 3467339; 3768366; 3840606; 4041237; 6083474; 6201756; 7522741; 7531827; 7539213; 7541731; 7573159; 7679906; 7683951; 7684886; 7684945; 8012387; 8696336; 8765335; 8780101; 8909455; 8956049; 9008538; 9143933; 9247276; 9489796; 9633722; 9728768; 9747038; 9788732; 9858696; 9894878; 9934976; 10203813; 10319897; 10417279; 10520936; 10767322; 11093273; 11872612; 12107410; 12196561; 12237860; 12297985; 12325077; 12477932; 12491939; 12601703; 12805210; 14572140; 14702039; 15009677; 15450775; 15489334; 15627202; 15694262; 15712223; 15753308; 15772651; 15837131; 16130097; 16287154; 16374829; 16380909; 16416265; 16774974; 17171701; 17420921; 17438221; 17500595; 17962415; 18190592; 18437021; 18470932; 18555697; 18604471; 19024090; 19151366; 19244236; 19328639; 19376225; 19396823; 19562355; 19825935; 19955111; 20036320; 20186781; 20301361; 20437587; 20629189; 20885931; 21082496; 21127064; 21177054; 21573057; 21623770; 21679407; 22343157; 22511562; 22695888; 22750001; 22902553; 23142642; 23344956; 24103481; 24519770 proteolipid protein 1 Ensembl:ENSG00000123560 HGNC:9086 HPRD:02321 MIM:300401 Vega:OTTHUMG00000022111 PLP1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene POLB polymerase (DNA directed), beta 5423 8p11.2 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0003684 (EC: IEA); GO_0003887 (EC: IDA, PMID: 16600869); GO_0005515 (EC: IPI, PMID: 15520167); GO_0005634 (EC: IDA, PMID: 19713937); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA, PMID: 15725623); GO_0005874 (EC: IDA, PMID: 15725623); GO_0005876 (EC: IDA, PMID: 15725623); GO_0006261 (EC: TAS, PMID: 8168825); GO_0006281 (EC: TAS); GO_0006284 (EC: IDA, PMID: 16600869); GO_0006284 (EC: IMP); GO_0006284 (EC: TAS); GO_0006287 (EC: IEA); GO_0006290 (EC: IEA); GO_0006297 (EC: IMP, Qualifier: NOT); GO_0006974 (EC: IMP); GO_0008017 (EC: IDA, PMID: 15725623); GO_0008630 (EC: IEA); GO_0016829 (EC: IDA, PMID: 16600869); GO_0019899 (EC: IPI, PMID: 16600869); GO_0045471 (EC: IEA); GO_0046872 (EC: IEA); GO_0051402 (EC: IEA); GO_0071897 (EC: IEA) PMID: 1408801; 1511447; 2040602; 2423078; 2460824; 3182828; 3284575; 7705833; 7914364; 8125298; 8168825; 8769567; 8841118; 8841119; 8841120; 8889548; 8978692; 9207062; 9287163; 9294209; 9572863; 10559261; 10629618; 11163244; 11242139; 11250913; 11467963; 11756435; 11805079; 11827474; 11912205; 11923315; 11955015; 12063248; 12067997; 12173936; 12196536; 12370169; 12453427; 12477932; 12517346; 12665521; 14506279; 14627836; 14988403; 15107487; 15145936; 15260972; 15314187; 15342556; 15367657; 15489334; 15520167; 15548520; 15561706; 15601998; 15725623; 15731342; 15753095; 15764500; 15963946; 16060670; 16169070; 16188889; 16195237; 16543152; 16600869; 16609022; 17065437; 17127106; 17131038; 17173071; 17176113; 17203305; 17209556; 17230526; 17283177; 17286973; 17321545; 17355977; 17526740; 17855454; 18006695; 18039710; 18161950; 18270339; 18313385; 18471977; 18676680; 18686630; 18937502; 19104052; 19120024; 19147782; 19167932; 19170196; 19237606; 19329428; 19330779; 19336415; 19339270; 19536092; 19625176; 19635489; 19692168; 19713937; 19747104; 19838217; 19842163; 20006562; 20150366; 20226869; 20302655; 20303835; 20403997; 20423048; 20459144; 20465217; 20496165; 20519499; 20522537; 20526335; 20574454; 20805875; 21107011; 21139048; 21305655; 21362556; 21733843; 21739967; 21757740; 21884718; 22070286; 22082156; 22162999; 22341651; 22373917; 22379092; 22573322; 22577134; 22692827; 22799326; 22901161; 23013478; 23098424; 23117284; 23144153; 23144635; 23144716; 23585564; 23602568; 23749489; 23798703; 23827680; 24133209 polymerase (DNA directed), beta POLB Bin Zhao, Yue Liu, Oliver He CDC2 CRCS10 MDPL POLD WEB: http://www.ncbi.nlm.nih.gov/gene POLD1 polymerase (DNA directed), delta 1, catalytic subunit 5424 19q13.3 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000109 (EC: IDA); GO_0000166 (EC: IEA); GO_0000278 (EC: TAS); GO_0000722 (EC: TAS); GO_0000723 (EC: TAS); GO_0000731 (EC: IDA, PMID: 3335506); GO_0000731 (EC: IMP, PMID: 1730053); GO_0003677 (EC: IDA, PMID: 16762037); GO_0003682 (EC: IDA, PMID: 16762037); GO_0003887 (EC: IMP, PMID: 16762037); GO_0005515 (EC: IPI, PMID: 12403614); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0006260 (EC: IMP, PMID: 16762037); GO_0006271 (EC: TAS); GO_0006281 (EC: TAS); GO_0006283 (EC: TAS); GO_0006284 (EC: TAS); GO_0006287 (EC: IDA, PMID: 10559260); GO_0006289 (EC: TAS); GO_0006297 (EC: IC); GO_0006297 (EC: IMP); GO_0006297 (EC: TAS); GO_0007346 (EC: IBA); GO_0008408 (EC: IBA); GO_0009411 (EC: TAS, PMID: 3146346); GO_0016235 (EC: IDA); GO_0019985 (EC: IBA, Qualifier: NOT); GO_0032201 (EC: TAS); GO_0043137 (EC: IBA); GO_0043625 (EC: IBA); GO_0044281 (EC: TAS); GO_0045004 (EC: IBA); GO_0046872 (EC: IEA); GO_0051539 (EC: IEA); GO_0055089 (EC: IMP); GO_0090305 (EC: IBA) PMID: 1427831; 1542570; 1722322; 1730053; 2436659; 3146346; 3335506; 7490075; 8889549; 9030545; 9111189; 9286699; 9545286; 9563011; 9620226; 10559260; 10559261; 10608806; 10852724; 11328591; 11473323; 11923315; 12171929; 12220650; 12393188; 12403614; 12477932; 12530964; 12806015; 14767555; 14988403; 15113441; 15489334; 15670210; 15805117; 15995249; 16169070; 16196087; 16226712; 16488880; 16510448; 16543152; 16762037; 16934752; 17203305; 17314511; 17353931; 17474147; 18247557; 18270339; 18676680; 18701435; 19170196; 19237606; 19329428; 19557333; 19625176; 19692168; 19913121; 20070946; 20226869; 20227374; 20496165; 20522537; 20541997; 20574454; 20628086; 20811636; 21044950; 21139048; 21145461; 21252943; 21415862; 21705323; 21890473; 21906983; 21918226; 21963094; 21987572; 22465957; 22505724; 22678362; 22761421; 22863883; 22887995; 22915169; 22939629; 22942285; 23000965; 23251661; 23263490; 23447401; 23528559; 23585564; 23738518; 23770608; 24250222; 24457600; 24509466 polymerase (DNA directed), delta 1, catalytic subunit Ensembl:ENSG00000062822 HGNC:9175 HPRD:08882 MIM:174761 Vega:OTTHUMG00000183037 POLD1 Bin Zhao, Yue Liu, Oliver He NR1C1 PPAR PPARalpha hPPAR WEB: http://www.ncbi.nlm.nih.gov/gene PPARA peroxisome proliferator-activated receptor alpha 5465 SC22CB-5E3.5 22q13.31 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0000122 (EC: IDA, PMID: 12700342); GO_0001103 (EC: IPI, PMID: 19955185); GO_0001666 (EC: IEA); GO_0003677 (EC: TAS, PMID: 10860941); GO_0003700 (EC: IDA, PMID: 19955185); GO_0003700 (EC: ISS); GO_0003707 (EC: IDA, PMID: 19955185); GO_0004879 (EC: IDA, PMID: 12955147); GO_0005515 (EC: IPI, PMID: 11915042); GO_0005634 (EC: TAS, PMID: 16271724); GO_0005654 (EC: TAS); GO_0006367 (EC: TAS); GO_0006629 (EC: TAS, PMID: 7684926); GO_0006631 (EC: IEA); GO_0007507 (EC: IEA); GO_0008144 (EC: IDA, PMID: 12955147); GO_0008270 (EC: IEA); GO_0008289 (EC: IDA, PMID: 12955147); GO_0008544 (EC: IEA); GO_0010467 (EC: TAS); GO_0010745 (EC: IC, PMID: 12700342); GO_0010745 (EC: IDA, PMID: 19114110); GO_0010871 (EC: IDA, PMID: 12700342); GO_0010887 (EC: IDA, PMID: 19114110); GO_0010891 (EC: IDA, PMID: 12700342); GO_0015908 (EC: TAS, PMID: 16271724); GO_0019902 (EC: IEA); GO_0019904 (EC: IEA); GO_0030522 (EC: IDA, PMID: 12955147); GO_0031624 (EC: IPI, PMID: 19955185); GO_0032000 (EC: TAS, PMID: 16271724); GO_0032091 (EC: IEA); GO_0032099 (EC: ISS); GO_0032403 (EC: IEA); GO_0032868 (EC: IEA); GO_0035095 (EC: IEA); GO_0042060 (EC: IEA); GO_0042157 (EC: IEA); GO_0043565 (EC: ISS); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0045776 (EC: IEA); GO_0045820 (EC: IC, PMID: 19955185); GO_0045893 (EC: IDA, PMID: 12955147); GO_0045944 (EC: IDA, PMID: 19955185); GO_0046321 (EC: ISS); GO_0051525 (EC: IEA); GO_0070166 (EC: IEA); GO_0072363 (EC: IDA, PMID: 19955185); GO_0072366 (EC: IDA, PMID: 19955185); GO_0072369 (EC: IDA, PMID: 19955185); GO_0097371 (EC: IEA); GO_1901215 (EC: IEA); GO_2000678 (EC: IEA) PMID: 7684926; 7981125; 8621574; 8910358; 8993548; 9113987; 9238002; 9407140; 9610365; 9626662; 9627117; 9653119; 9748221; 9792666; 9795230; 9915808; 10022764; 10187842; 10195690; 10336495; 10377439; 10403814; 10542237; 10591208; 10669761; 10681503; 10731636; 10786636; 10860941; 10862523; 10872826; 10903152; 11119019; 11226238; 11337467; 11375929; 11409711; 11466580; 11587644; 11668221; 11698662; 11733490; 11818483; 11840500; 11845213; 11852057; 11864924; 11891224; 11897617; 11897821; 11914252; 11915042; 11923467; 11934839; 11940516; 11980898; 11981036; 12006394; 12023905; 12039952; 12042669; 12048138; 12055195; 12118000; 12118038; 12161442; 12163133; 12189208; 12203367; 12208475; 12395215; 12408750; 12468272; 12477932; 12482853; 12544508; 12554753; 12562861; 12594295; 12594814; 12615366; 12655356; 12700342; 12709436; 12745064; 12810707; 12835617; 12847522; 12855749; 12897377; 12914524; 12932225; 12938026; 12955147; 12962497; 14515181; 14519597; 14523052; 14633846; 14641801; 14671555; 14677049; 14702039; 14730379; 14764586; 14999402; 15001458; 15001550; 15051727; 15067378; 15083308; 15111510; 15128052; 15131257; 15196699; 15199365; 15221005; 15231516; 15258199; 15309680; 15318936; 15456881; 15461802; 15497675; 15500444; 15521013; 15539630; 15549499; 15608561; 15615782; 15642120; 15677519; 15685545; 15699244; 15699916; 15735069; 15759454; 15797250; 15811118; 15870285; 15888456; 15935279; 15940190; 16042408; 16043164; 16162941; 16169070; 16189514; 16221474; 16226051; 16239970; 16271724; 16275545; 16285997; 16288935; 16288986; 16297361; 16309557; 16377806; 16416313; 16492688; 16506057; 16511589; 16554032; 16630553; 16637234; 16652134; 16763159; 16806233; 16822823; 16847426; 16875506; 16956579; 17001213; 17008383; 17084382; 17129741; 17150915; 17181634; 17184146; 17195188; 17200111; 17244467; 17272748; 17300045; 17317762; 17331954; 17342071; 17355223; 17356846; 17363697; 17363837; 17431031; 17436029; 17492134; 17608096; 17616429; 17646210; 17655842; 17700210; 17705849; 17850927; 17926914; 17951966; 17962186; 17963696; 17991667; 17998026; 18003597; 18004978; 18061194; 18172578; 18182682; 18184928; 18219093; 18245819; 18255343; 18268046; 18292238; 18313368; 18336366; 18388689; 18394939; 18398047; 18440986; 18518955; 18541586; 18549840; 18586686; 18652775; 18660489; 18680716; 18710415; 18713766; 18725353; 18726867; 18727927; 18786524; 18787507; 18797151; 18848838; 18853997; 18855529; 18955051; 18977277; 18981151; 18996102; 19070893; 19114110; 19115207; 19118026; 19119483; 19141539; 19157507; 19208777; 19217440; 19223982; 19254215; 19255064; 19263263; 19279199; 19357976; 19362162; 19367093; 19386311; 19420105; 19422369; 19422653; 19433068; 19451226; 19453261; 19458633; 19527689; 19560472; 19628794; 19653005; 19660836; 19681917; 19706994; 19710929; 19733654; 19748481; 19776627; 19780876; 19782026; 19789836; 19822141; 19823578; 19828088; 19878569; 19887568; 19913121; 19937854; 19948841; 19948975; 19955185; 20016041; 20044476; 20045185; 20070029; 20178979; 20214982; 20238044; 20346360; 20379614; 20384434; 20385772; 20399568; 20400503; 20414453; 20421589; 20426853; 20450745; 20452482; 20466884; 20485444; 20496064; 20602615; 20620111; 20628086; 20638986; 20647061; 20653996; 20656057; 20673868; 20679960; 20682687; 20800603; 20810571; 20811626; 20825652; 20838448; 20855565; 20862655; 21030426; 21125992; 21159535; 21245137; 21282101; 21291392; 21304969; 21326871; 21430558; 21443859; 21487230; 21540177; 21562928; 21785974; 21967852; 21988832; 21990353; 22040870; 22065208; 22068265; 22089192; 22092351; 22168458; 22205725; 22215653; 22266374; 22315317; 22336959; 22349506; 22378291; 22435679; 22479552; 22510778; 22547144; 22647601; 22649490; 22654113; 22685582; 22920733; 22932900; 22940187; 22944052; 22983821; 22989886; 23141142; 23144166; 23158661; 23160450; 23208589; 23262340; 23295386; 23329136; 23372804; 23455924; 23476056; 23502212; 23522297; 23567058; 23583468; 23645771; 23657974; 23666678; 23707408; 23711995; 23736812; 23811234; 23814018; 23821302; 23891824; 23919842; 23930676; 24140347; 24169559; 24309288 peroxisome proliferator-activated receptor alpha Ensembl:ENSG00000186951 HGNC:9232 HPRD:01369 MIM:170998 Vega:OTTHUMG00000150443 PPARA Bin Zhao, Yue Liu, Oliver He CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma WEB: http://www.ncbi.nlm.nih.gov/gene PPARG peroxisome proliferator-activated receptor gamma 5468 3p25 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000122 (EC: IDA, PMID: 12700342); GO_0000122 (EC: ISS); GO_0001012 (EC: IEA); GO_0001890 (EC: ISS); GO_0002674 (EC: IEA); GO_0003677 (EC: IDA, PMID: 16239304); GO_0003677 (EC: ISS); GO_0003682 (EC: IEA); GO_0003700 (EC: IDA, PMID: 9568715); GO_0003700 (EC: ISS); GO_0003707 (EC: IEA); GO_0004879 (EC: IDA, PMID: 10622252); GO_0004955 (EC: TAS, PMID: 9568715); GO_0005515 (EC: IPI, PMID: 10428834); GO_0005634 (EC: IDA, PMID: 9568716); GO_0005654 (EC: TAS); GO_0005829 (EC: ISS); GO_0006367 (EC: TAS); GO_0006629 (EC: TAS, PMID: 9568716); GO_0006919 (EC: IDA, PMID: 18293083); GO_0007165 (EC: IDA, PMID: 9568716); GO_0007186 (EC: TAS, PMID: 9568715); GO_0007507 (EC: IEA); GO_0007584 (EC: TAS, PMID: 10973253); GO_0008144 (EC: IDA, PMID: 10622252); GO_0008217 (EC: IMP, PMID: 10622252); GO_0008270 (EC: IEA); GO_0009409 (EC: IEA); GO_0010467 (EC: TAS); GO_0010745 (EC: IC, PMID: 12700342); GO_0010745 (EC: IDA, PMID: 19114110); GO_0010871 (EC: IDA, PMID: 12700342); GO_0010887 (EC: IDA, PMID: 19114110); GO_0010891 (EC: IDA, PMID: 12700342); GO_0015909 (EC: ISS); GO_0019395 (EC: IEA); GO_0019899 (EC: IPI, PMID: 12039952); GO_0030224 (EC: IDA, PMID: 9568716); GO_0030308 (EC: IEA); GO_0030374 (EC: IDA, PMID: 16239304); GO_0030855 (EC: ISS); GO_0031000 (EC: IEA); GO_0031100 (EC: IEA); GO_0032526 (EC: IDA, PMID: 16239304); GO_0032869 (EC: IMP, PMID: 10622252); GO_0033189 (EC: IEA); GO_0033613 (EC: IDA, PMID: 10622252); GO_0033993 (EC: ISS, PMID: 9568715); GO_0035357 (EC: IMP); GO_0042493 (EC: IEA); GO_0042593 (EC: IMP, PMID: 10622252); GO_0042953 (EC: IDA, PMID: 9568716); GO_0043565 (EC: IDA, Qualifier: contributes_to, PMID: 9568716); GO_0043627 (EC: IEA); GO_0044212 (EC: IDA, PMID: 18293083); GO_0044212 (EC: ISS); GO_0045087 (EC: TAS, PMID: 17145956); GO_0045165 (EC: ISS); GO_0045600 (EC: ISS); GO_0045713 (EC: IDA, PMID: 9568716); GO_0045892 (EC: ISS); GO_0045893 (EC: ISS); GO_0045944 (EC: IDA, PMID: 12700342); GO_0045944 (EC: IMP); GO_0046321 (EC: IEA); GO_0046965 (EC: IDA, PMID: 9568715); GO_0048469 (EC: IDA, PMID: 9568716); GO_0048662 (EC: IDA); GO_0048714 (EC: IEA); GO_0050544 (EC: ISS, PMID: 9568715); GO_0050872 (EC: ISS); GO_0050872 (EC: TAS, PMID: 12588810); GO_0050873 (EC: IEA); GO_0051091 (EC: IDA, PMID: 18293083); GO_0051974 (EC: IEA); GO_0055088 (EC: TAS, PMID: 9113987); GO_0055098 (EC: IDA, PMID: 9568716); GO_0060336 (EC: IMP); GO_0060694 (EC: IC, PMID: 17611579); GO_0060850 (EC: ISS); GO_0071285 (EC: IEA) PMID: 1504714; 7787419; 7838715; 8001151; 8125298; 8702406; 9030579; 9041124; 9065481; 9113987; 9121466; 9144532; 9168928; 9228052; 9325263; 9356045; 9568715; 9568716; 9626662; 9653119; 9744270; 9750197; 9753710; 9813012; 9918859; 10037764; 10075656; 10339548; 10347167; 10394368; 10407229; 10428834; 10428835; 10517671; 10558993; 10622252; 10681503; 10731636; 10781090; 10788465; 10842190; 10843155; 10848596; 10854698; 10872826; 10882139; 10930400; 10935544; 10973253; 10974018; 11027271; 11069206; 11079814; 11226238; 11242476; 11246892; 11248748; 11289055; 11315829; 11330046; 11334419; 11402923; 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17222225; 17227883; 17255125; 17259396; 17259473; 17270153; 17272748; 17287921; 17292728; 17307204; 17312272; 17321592; 17322577; 17322631; 17322785; 17325208; 17329993; 17330131; 17331464; 17335469; 17342071; 17342473; 17348446; 17351148; 17351273; 17355643; 17356052; 17356846; 17359638; 17369494; 17372612; 17374678; 17374711; 17380316; 17399685; 17408525; 17415545; 17428620; 17434720; 17436029; 17439324; 17440948; 17455211; 17459764; 17461486; 17462987; 17463246; 17463248; 17463249; 17465682; 17466258; 17468099; 17473186; 17482764; 17483060; 17487454; 17492134; 17493550; 17495181; 17495182; 17513608; 17521736; 17532820; 17535427; 17535976; 17544013; 17553506; 17563457; 17565986; 17570749; 17573040; 17574226; 17587797; 17588204; 17601994; 17611194; 17611413; 17611579; 17611675; 17612754; 17614769; 17616777; 17624182; 17628005; 17643887; 17651710; 17653445; 17658197; 17664351; 17665979; 17681149; 17681394; 17696929; 17700648; 17704298; 17763950; 17765929; 17766367; 17785586; 17785633; 17785925; 17803977; 17805195; 17805473; 17852881; 17868335; 17870167; 17874829; 17884443; 17890503; 17892998; 17896990; 17898990; 17902047; 17903300; 17921408; 17926914; 17928738; 17929009; 17932108; 17937104; 17941898; 17952062; 17980149; 17985660; 17994213; 17998334; 17999084; 17999673; 18004978; 18055759; 18077048; 18077140; 18082740; 18091023; 18096664; 18158351; 18159845; 18160010; 18160840; 18162503; 18164040; 18172578; 18182682; 18182855; 18187557; 18198294; 18202670; 18203887; 18204431; 18204896; 18209083; 18211635; 18212765; 18214615; 18217139; 18234854; 18241614; 18242157; 18247297; 18250615; 18263601; 18268046; 18268966; 18271689; 18280041; 18282590; 18288282; 18292390; 18293083; 18310298; 18313022; 18313368; 18316027; 18317434; 18317435; 18317436; 18317437; 18346728; 18362424; 18370824; 18372284; 18372903; 18379566; 18381063; 18382765; 18388689; 18388889; 18391483; 18398047; 18411276; 18413760; 18417957; 18424599; 18426861; 18426866; 18435931; 18443916; 18450755; 18451773; 18465691; 18466209; 18467141; 18469005; 18483152; 18490773; 18496506; 18498634; 18507082; 18509005; 18513389; 18516296; 18516622; 18535203; 18538667; 18544633; 18547997; 18551086; 18555503; 18556801; 18561518; 18573313; 18578080; 18579355; 18591388; 18593980; 18597214; 18598350; 18604218; 18608213; 18624999; 18634911; 18639367; 18645029; 18645733; 18657264; 18657335; 18660489; 18676352; 18676680; 18676870; 18680073; 18683148; 18688264; 18688583; 18697866; 18707223; 18710329; 18710415; 18711014; 18713822; 18718916; 18724972; 18727927; 18753860; 18755275; 18756295; 18757431; 18777501; 18786524; 18789381; 18789607; 18789822; 18809223; 18822908; 18823720; 18828733; 18832723; 18836859; 18845641; 18855061; 18927280; 18927468; 18931513; 18936159; 18936436; 18959602; 18972257; 18977231; 18977277; 18984664; 18992148; 18992263; 18996102; 18996470; 18997828; 19000312; 19002430; 19016747; 19018532; 19020036; 19020323; 19020324; 19028452; 19035184; 19043829; 19046432; 19052558; 19053776; 19056482; 19056576; 19059241; 19061500; 19064572; 19070258; 19073146; 19081837; 19088437; 19101554; 19104705; 19114110; 19116451; 19117570; 19121846; 19125195; 19126543; 19130493; 19131662; 19139842; 19141539; 19147680; 19148128; 19156545; 19157507; 19170196; 19178525; 19179433; 19186181; 19188432; 19193342; 19193378; 19199260; 19201410; 19208777; 19217272; 19223982; 19225753; 19225884; 19228871; 19237017; 19247372; 19254215; 19263529; 19267370; 19267951; 19279076; 19279199; 19282863; 19283612; 19303976; 19324937; 19338578; 19342081; 19345798; 19346318; 19358337; 19367093; 19376812; 19380830; 19380854; 19383491; 19389254; 19395102; 19395477; 19405075; 19418728; 19422369; 19432669; 19436234; 19438902; 19443733; 19453261; 19454659; 19455305; 19465486; 19470259; 19470430; 19471887; 19479237; 19484168; 19485965; 19491387; 19494505; 19495794; 19500413; 19502414; 19506043; 19506796; 19524923; 19526109; 19534662; 19535643; 19536733; 19536736; 19540934; 19543210; 19548113; 19549442; 19558269; 19560328; 19563910; 19569080; 19578796; 19581903; 19583951; 19587357; 19592620; 19596656; 19596783; 19602701; 19609844; 19622037; 19624894; 19625176; 19625650; 19627000; 19631630; 19631645; 19633298; 19634985; 19644041; 19644638; 19651920; 19660836; 19673747; 19680556; 19681917; 19683227; 19692168; 19692572; 19701967; 19712722; 19714744; 19720797; 19720844; 19724872; 19727905; 19729601; 19730683; 19733160; 19737866; 19745552; 19756148; 19760027; 19760975; 19766907; 19772889; 19787196; 19789190; 19794065; 19796634; 19797117; 19797172; 19800867; 19805902; 19808645; 19808901; 19818126; 19829671; 19837787; 19846173; 19846176; 19846218; 19846795; 19850645; 19859551; 19862325; 19876004; 19878569; 19884280; 19887620; 19888469; 19890028; 19898482; 19900151; 19913121; 19915048; 19923924; 19948841; 19948975; 19951908; 19956635; 19958503; 19963130; 19996102; 20016803; 20021832; 20021931; 20026644; 20032081; 20032817; 20033348; 20042507; 20043145; 20045142; 20045185; 20045799; 20054646; 20059631; 20062524; 20070029; 20070288; 20075150; 20078877; 20079163; 20093779; 20102333; 20112822; 20123124; 20130411; 20145925; 20158084; 20161779; 20164187; 20174813; 20178607; 20179158; 20186155; 20194623; 20198337; 20203524; 20211142; 20221637; 20224667; 20238044; 20299237; 20302927; 20334678; 20346360; 20357037; 20360975; 20361309; 20364085; 20368233; 20372080; 20372816; 20384434; 20388362; 20392673; 20399568; 20403997; 20406953; 20413122; 20420754; 20421464; 20424228; 20426853; 20430250; 20437058; 20437825; 20440859; 20450366; 20450751; 20452482; 20453000; 20468064; 20484415; 20485444; 20490451; 20492333; 20501643; 20503258; 20510503; 20512451; 20512989; 20536507; 20540670; 20542036; 20543477; 20550665; 20554962; 20556576; 20558736; 20560917; 20568969; 20571754; 20573495; 20580033; 20580778; 20581827; 20591056; 20596649; 20600006; 20602615; 20606394; 20608974; 20616309; 20621019; 20623456; 20628086; 20631015; 20640553; 20644561; 20645257; 20649594; 20650551; 20651683; 20653996; 20656057; 20668019; 20668149; 20672248; 20673868; 20679960; 20682687; 20693905; 20694299; 20712903; 20715992; 20717101; 20722066; 20723894; 20732852; 20733583; 20734064; 20734220; 20738756; 20800603; 20811626; 20816152; 20825652; 20829347; 20840271; 20848495; 20853849; 20855565; 20857895; 20861226; 20862655; 20870032; 20879858; 20885348; 20889551; 20889853; 20923526; 20929345; 20929593; 20930717; 20945045; 20951680; 20970965; 21029675; 21040163; 21044285; 21054877; 21057731; 21059469; 21059659; 21061265; 21072170; 21093321; 21095215; 21104228; 21105983; 21106862; 21109018; 21135128; 21135166; 21140205; 21146687; 21148223; 21150196; 21151932; 21155004; 21156825; 21156835; 21159608; 21176858; 21185561; 21206011; 21206970; 21207518; 21229639; 21233811; 21245597; 21245992; 21247904; 21251908; 21252350; 21253589; 21263402; 21265110; 21266034; 21284483; 21288452; 21291392; 21292830; 21296999; 21301856; 21317313; 21325464; 21350215; 21358044; 21410980; 21415255; 21426847; 21451128; 21457357; 21467033; 21473290; 21478865; 21479595; 21487230; 21489836; 21493814; 21501146; 21508507; 21528816; 21540831; 21544861; 21548985; 21570865; 21612582; 21613824; 21619898; 21632707; 21637537; 21643757; 21646797; 21664456; 21664967; 21669017; 21674037; 21690289; 21700710; 21704006; 21704384; 21709632; 21710534; 21726861; 21734368; 21756892; 21763631; 21764381; 21765467; 21781307; 21785974; 21795447; 21820420; 21821917; 21827375; 21832049; 21833030; 21833536; 21853931; 21861709; 21885829; 21896780; 21911496; 21939732; 21949049; 21967852; 21968139; 21982524; 21986665; 21986923; 21988832; 22001530; 22001700; 22009745; 22017455; 22020928; 22021335; 22025054; 22040870; 22056426; 22078880; 22095559; 22102511; 22103651; 22108328; 22120652; 22120719; 22129188; 22152242; 22160635; 22168210; 22169113; 22174394; 22179955; 22192353; 22205725; 22207732; 22210720; 22240811; 22248180; 22268120; 22276212; 22282354; 22286757; 22293175; 22301832; 22321707; 22334075; 22342541; 22349439; 22349506; 22363123; 22363753; 22366735; 22377103; 22378291; 22410809; 22413765; 22426809; 22435140; 22455954; 22456356; 22475777; 22487967; 22489460; 22515931; 22519881; 22527903; 22537818; 22544925; 22558273; 22561695; 22564702; 22573555; 22575725; 22581228; 22583414; 22584573; 22619290; 22647601; 22651256; 22653647; 22664386; 22684020; 22685582; 22689692; 22694222; 22716961; 22724641; 22729915; 22739234; 22750678; 22766852; 22787115; 22800638; 22814748; 22819264; 22820754; 22840054; 22843091; 22843934; 22853971; 22860094; 22871496; 22884583; 22910911; 22934513; 22940187; 22944052; 22949934; 22954708; 22961909; 22968431; 22985084; 22987045; 22990020; 22992727; 22993124; 22993484; 23006958; 23031808; 23036708; 23036713; 23054024; 23060450; 23064015; 23065280; 23088980; 23096090; 23113754; 23118933; 23130662; 23142027; 23145084; 23147557; 23161442; 23168911; 23202735; 23212831; 23219716; 23220503; 23223023; 23237621; 23239344; 23250430; 23254958; 23256116; 23262340; 23266668; 23273766; 23275339; 23300871; 23315125; 23317272; 23320500; 23339868; 23364967; 23370527; 23386649; 23393388; 23417417; 23418723; 23424659; 23426382; 23436219; 23438152; 23448101; 23461356; 23483194; 23502212; 23514940; 23516550; 23525438; 23530462; 23531513; 23545576; 23549616; 23555077; 23559865; 23562554; 23574724; 23583468; 23583560; 23593291; 23604462; 23612072; 23640498; 23647960; 23652363; 23684777; 23687300; 23703729; 23711995; 23716627; 23736812; 23738683; 23748472; 23754948; 23770845; 23776688; 23799144; 23803735; 23811234; 23887394; 23891820; 23891824; 24012868; 24027433; 24064359; 24072712; 24169559; 24219556; 24308220; 24332944; 24374034; 24431460 peroxisome proliferator-activated receptor gamma Ensembl:ENSG00000132170 HGNC:9236 HPRD:03288 MIM:601487 Vega:OTTHUMG00000129764 PPARG Bin Zhao, Yue Liu, Oliver He PP2Ac PP2CA PP2Calpha RP-C WEB: http://www.ncbi.nlm.nih.gov/gene PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 5515 5q31.1 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0000159 (EC: IDA, PMID: 17055435); GO_0000159 (EC: TAS, PMID: 11007961); GO_0000184 (EC: TAS); GO_0000188 (EC: NAS, PMID: 11007961); GO_0000278 (EC: TAS); GO_0000775 (EC: IEA); GO_0000922 (EC: IEA); GO_0004722 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11591705); GO_0005634 (EC: NAS, PMID: 11007961); GO_0005739 (EC: NAS, PMID: 11007961); GO_0005829 (EC: TAS, PMID: 11007961); GO_0005886 (EC: IEA); GO_0006275 (EC: NAS, PMID: 11007961); GO_0006355 (EC: NAS, PMID: 11007961); GO_0006470 (EC: TAS, PMID: 11007961); GO_0006672 (EC: NAS, PMID: 11007961); GO_0006915 (EC: TAS, PMID: 11007961); GO_0007084 (EC: TAS); GO_0007126 (EC: IEA); GO_0007498 (EC: IEA); GO_0008022 (EC: IEA); GO_0008380 (EC: NAS, PMID: 11007961); GO_0008543 (EC: TAS); GO_0010033 (EC: NAS, PMID: 11007961); GO_0010467 (EC: TAS); GO_0010469 (EC: IEA); GO_0010719 (EC: IMP); GO_0015630 (EC: NAS, PMID: 11007961); GO_0016020 (EC: NAS, PMID: 11007961); GO_0016070 (EC: TAS); GO_0016071 (EC: TAS); GO_0019932 (EC: NAS, PMID: 11007961); GO_0030111 (EC: NAS, PMID: 11007961); GO_0030155 (EC: NAS, PMID: 11007961); GO_0030308 (EC: NAS, PMID: 11007961); GO_0031952 (EC: IEA); GO_0040008 (EC: NAS, PMID: 11360189); GO_0042176 (EC: IEA); GO_0042518 (EC: NAS, PMID: 11007961); GO_0045595 (EC: NAS, PMID: 11360189); GO_0046872 (EC: IEA); GO_0046983 (EC: IEA); GO_0070062 (EC: IDA); GO_0070208 (EC: IEA); GO_0071902 (EC: IMP) PMID: 1328247; 1330687; 1846293; 1848320; 1848668; 2555176; 2557326; 2837763; 2849764; 4092695; 7592815; 8206937; 8262976; 8383590; 8386634; 8392375; 8524402; 8617797; 8617805; 8703017; 9003791; 9009195; 9013886; 9353299; 9400615; 9647778; 9795170; 9847399; 9852076; 9920888; 9989501; 10191253; 10200280; 10357815; 10441131; 10629059; 10644691; 10675325; 10681496; 10698523; 10769027; 10934208; 11007961; 11113010; 11114196; 11259605; 11278485; 11313937; 11360189; 11371618; 11438723; 11440634; 11531413; 11591705; 11842093; 11929874; 11929880; 11956189; 11959144; 11983168; 12036313; 12036952; 12054646; 12058047; 12062430; 12186863; 12370081; 12435421; 12477932; 12514180; 12556559; 12624094; 12637511; 12842894; 12859198; 12912990; 12915404; 14633983; 14645548; 14702039; 14724252; 15147202; 15231747; 15247211; 15252037; 15380617; 15489334; 15671020; 15761153; 15761952; 16041367; 16085932; 16109716; 16126728; 16169070; 16189514; 16191191; 16258073; 16306228; 16341674; 16456541; 16541025; 16580887; 16596250; 16764867; 17055435; 17110338; 17148452; 17163575; 17174897; 17245430; 17255109; 17266553; 17297438; 17374643; 17485487; 17540176; 17632056; 17693927; 17803990; 17852432; 17855368; 17941990; 17974561; 18160256; 18191226; 18299321; 18339811; 18430997; 18477699; 18583989; 18586681; 18715871; 18768864; 18782753; 18852266; 18928587; 18949047; 18971272; 18977201; 19060904; 19126401; 19131971; 19155497; 19156129; 19356149; 19360341; 19553685; 19738201; 19818709; 20065038; 20092282; 20100830; 20106966; 20133759; 20133760; 20360068; 20363734; 20448038; 20544796; 20558158; 20562864; 20615878; 20639865; 20663872; 20677014; 20711181; 20811636; 21072166; 21081666; 21139048; 21145461; 21151953; 21172653; 21346232; 21351466; 21355954; 21393425; 21454489; 21590681; 21708940; 21791414; 21835928; 21890473; 21906983; 21959857; 21963094; 21983900; 21987572; 21988832; 21996587; 22031698; 22053931; 22065577; 22135143; 22167190; 22192750; 22299668; 22314363; 22379092; 22422068; 22443683; 22466704; 22479341; 22505724; 22613722; 22623428; 22685328; 22732552; 22863883; 22904676; 22939629; 22961627; 22990118; 23000965; 23022380; 23064762; 23135275; 23183242; 23184937; 23185379; 23290789; 23402259; 23434594; 23455922; 23651848; 23677989; 23720779; 23775084; 23824909; 23892082; 23901063; 24064353; 24100030; 24145130; 24250222; 24269630 protein phosphatase 2, catalytic subunit, alpha isozyme HGNC:9299 HPRD:08912 MIM:176915 PPP2CA Bin Zhao, Yue Liu, Oliver He p49 WEB: http://www.ncbi.nlm.nih.gov/gene PRIM1 primase, DNA, polypeptide 1 (49kDa) 5557 12q13 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000082 (EC: TAS); GO_0000278 (EC: TAS); GO_0000722 (EC: TAS); GO_0000723 (EC: TAS); GO_0003896 (EC: IEA); GO_0005654 (EC: TAS); GO_0006269 (EC: TAS, PMID: 8026492); GO_0006270 (EC: TAS); GO_0006271 (EC: TAS); GO_0032201 (EC: TAS); GO_0046872 (EC: IEA); GO_1990077 (EC: IEA) PMID: 6693436; 8026492; 8125298; 8530050; 9268648; 9705292; 9822671; 10441007; 10504261; 11473323; 11917009; 12393188; 12477932; 15489334; 16169070; 17035231; 19615732; 20030400; 21139048; 21145461; 21890473; 21906983; 21963094; 22267201; 22505724; 22593576; 22678362; 22939629; 22990118; 23000965 primase, DNA, polypeptide 1 (49kDa) Ensembl:ENSG00000198056 HGNC:9369 HPRD:08899 MIM:176635 Vega:OTTHUMG00000170034 PRIM1 Bin Zhao, Yue Liu, Oliver He AMPK AMPK2 AMPKa2 PRKAA WEB: http://www.ncbi.nlm.nih.gov/gene PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 5563 1p31 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0003682 (EC: ISS); GO_0004672 (EC: TAS, PMID: 7959015); GO_0004674 (EC: ISS); GO_0004679 (EC: IDA, PMID: 18439900); GO_0005515 (EC: IPI, PMID: 18439900); GO_0005524 (EC: IEA); GO_0005654 (EC: TAS); GO_0005829 (EC: TAS); GO_0006112 (EC: TAS); GO_0006351 (EC: IEA); GO_0006355 (EC: IEA); GO_0006468 (EC: TAS, PMID: 7959015); GO_0006633 (EC: IEA); GO_0006695 (EC: IEA); GO_0006853 (EC: TAS); GO_0006914 (EC: IEA); GO_0006950 (EC: ISS); GO_0007050 (EC: TAS); GO_0007165 (EC: TAS, PMID: 7959015); GO_0008286 (EC: TAS); GO_0008610 (EC: ISS); GO_0010508 (EC: ISS); GO_0016055 (EC: IEA); GO_0031669 (EC: ISS); GO_0032007 (EC: ISS); GO_0035174 (EC: ISS); GO_0042149 (EC: ISS); GO_0042304 (EC: TAS); GO_0042593 (EC: ISS); GO_0042752 (EC: ISS); GO_0043066 (EC: ISS); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0045821 (EC: ISS); GO_0046872 (EC: IEA); GO_0047322 (EC: IEA); GO_0048511 (EC: IEA); GO_0050405 (EC: IEA); GO_0055089 (EC: ISS); GO_0061024 (EC: TAS); GO_2000505 (EC: ISS) PMID: 1322130; 1365882; 1536860; 2900138; 7959015; 7988703; 8889548; 9148944; 9224708; 10642499; 10698692; 10760274; 11052978; 11171059; 11257506; 11389854; 11500364; 11797013; 12067722; 12091379; 12391032; 12413941; 12427743; 12444247; 12456889; 12477932; 12511592; 12519745; 12663462; 12740371; 12788940; 12847291; 12853467; 12941758; 14532170; 14613924; 14651849; 14709557; 14729328; 14742438; 14985344; 14985505; 15024086; 15058305; 15060529; 15231718; 15297373; 15371448; 15489334; 15572372; 15640157; 16054041; 16054095; 16054096; 16275868; 16344560; 16483872; 16505254; 16518831; 16567511; 16598851; 16624523; 16670154; 16710414; 16801347; 16984726; 17179156; 17950019; 18029386; 18195011; 18439900; 18614941; 18674809; 18801964; 18836454; 18974883; 18996102; 19170765; 19434633; 19440859; 19470831; 19502591; 19528236; 19574280; 19616115; 19720090; 19720831; 19723084; 19728147; 19836452; 19913121; 19948975; 20124121; 20167927; 20217115; 20392842; 20558612; 20562859; 20602615; 20628086; 20647423; 20682687; 20821366; 20876741; 21139048; 21209024; 21344388; 21432774; 21543851; 21651489; 21673972; 21825219; 21963094; 22137581; 22212710; 22286170; 22305490; 22728651; 22897928; 22939624; 23000302; 23293026; 23396962; 23476055; 23723070 protein kinase, AMP-activated, alpha 2 catalytic subunit Ensembl:ENSG00000162409 HGNC:9377 HPRD:02735 MIM:600497 Vega:OTTHUMG00000008282 PRKAA2 Bin Zhao, Yue Liu, Oliver He 1 AAT8 PKG PRKG1B PRKGR1B cGK cGK 1 cGK1 cGKI cGKI-BETA cGKI-alpha WEB: http://www.ncbi.nlm.nih.gov/gene PRKG1 protein kinase, cGMP-dependent, type I 5592 RP11-346D6.1 10q11.2 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0001764 (EC: IEA); GO_0004692 (EC: IDA); GO_0005246 (EC: IDA); GO_0005515 (EC: IPI, PMID: 14608379); GO_0005524 (EC: IEA); GO_0005737 (EC: IDA); GO_0005794 (EC: IEA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 16990611); GO_0006468 (EC: TAS, PMID: 10851246); GO_0007165 (EC: IEA); GO_0007596 (EC: TAS); GO_0016358 (EC: IEA); GO_0030036 (EC: TAS, PMID: 10851246); GO_0030553 (EC: IEA); GO_0030900 (EC: IEA); GO_0043087 (EC: IMP, PMID: 14608379); GO_0090331 (EC: IMP, PMID: 16990611) PMID: 1377674; 1544322; 2168396; 2792381; 7589584; 8132598; 8182057; 8380342; 8613202; 8663267; 8688081; 9192852; 9308888; 9687510; 9829964; 10051666; 10449420; 10567269; 10601315; 10671526; 10681529; 10724174; 10851246; 10922374; 11175347; 11278298; 11278415; 11309393; 11884369; 12082086; 12082111; 12119292; 12175859; 12237340; 12477932; 12480535; 12571245; 12574812; 12609995; 12855709; 12933804; 14530262; 14532276; 14608379; 14679200; 14702039; 14983059; 15051728; 15107017; 15164054; 15192100; 15280395; 15489334; 15556942; 15632203; 15711749; 15851553; 15917860; 16131665; 16166082; 16249377; 16331690; 16344560; 16385451; 16407222; 16632465; 16990611; 17601797; 17904578; 17975119; 18029348; 18194177; 18496125; 18519826; 18593937; 18617565; 18757735; 18782776; 18945831; 18983522; 19023099; 19023132; 19424179; 19487814; 19656393; 19851296; 19913121; 19961855; 19996273; 20006992; 20043968; 20068229; 20182759; 20198315; 20348951; 20371672; 20379614; 20567233; 20600009; 20628086; 20732627; 20826808; 21160032; 21402151; 21414799; 21451103; 21479273; 21526164; 21563174; 21697861; 21907864; 22095901; 22293199; 22580283; 22791569; 22806632; 23066013; 23195829; 23251661; 23382691; 23416533; 23418348; 23686857; 23770744; 23793025; 23814119; 23831687; 23876037; 23910461; 24060892; 24060898; 24163370 protein kinase, cGMP-dependent, type I Ensembl:ENSG00000185532 HGNC:9414 HPRD:08910 MIM:176894 Vega:OTTHUMG00000018248 PRKG1 Bin Zhao, Yue Liu, Oliver He ERK ERK-2 ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk p42-MAPK WEB: http://www.ncbi.nlm.nih.gov/gene MAPK1 mitogen-activated protein kinase 1 5594 22q11.21 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0000165 (EC: TAS); GO_0000186 (EC: TAS); GO_0000187 (EC: TAS); GO_0000189 (EC: IEA); GO_0001784 (EC: IEA); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0003677 (EC: IEA); GO_0004674 (EC: IDA, PMID: 15850461); GO_0004707 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10415025); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005634 (EC: TAS, PMID: 19565474); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA, PMID: 18794356); GO_0005737 (EC: ISS); GO_0005739 (EC: TAS, PMID: 19565474); GO_0005769 (EC: TAS, PMID: 19565474); GO_0005770 (EC: TAS, PMID: 19565474); GO_0005794 (EC: TAS, PMID: 19565474); GO_0005815 (EC: IEA); GO_0005829 (EC: TAS, PMID: 19565474); GO_0005856 (EC: TAS, PMID: 19565474); GO_0005901 (EC: TAS, PMID: 19565474); GO_0005925 (EC: TAS, PMID: 19565474); GO_0006351 (EC: IEA); GO_0006915 (EC: IEA); GO_0006935 (EC: TAS, PMID: 10706854); GO_0006950 (EC: TAS, PMID: 10958679); GO_0006974 (EC: IEA); GO_0007049 (EC: IEA); GO_0007165 (EC: TAS, PMID: 1540184); GO_0007173 (EC: TAS); GO_0007264 (EC: TAS); GO_0007265 (EC: TAS); GO_0007268 (EC: TAS); GO_0007411 (EC: TAS); GO_0007596 (EC: TAS); GO_0008134 (EC: IEA); GO_0008284 (EC: IEA); GO_0008286 (EC: TAS); GO_0008353 (EC: ISS); GO_0008543 (EC: TAS); GO_0009636 (EC: IEA); GO_0009887 (EC: IEA); GO_0010800 (EC: IDA, PMID: 16314496); GO_0015630 (EC: IDA); GO_0016032 (EC: IEA); GO_0018105 (EC: IDA, PMID: 15850461); GO_0018107 (EC: ISS); GO_0019233 (EC: IEA); GO_0019858 (EC: IEA); GO_0019902 (EC: IPI, PMID: 19494114); GO_0030168 (EC: TAS); GO_0030335 (EC: IEA); GO_0031143 (EC: IEA); GO_0031435 (EC: IEA); GO_0031647 (EC: ISS); GO_0031663 (EC: IEA); GO_0032839 (EC: IEA); GO_0032872 (EC: TAS, PMID: 19565474); GO_0033598 (EC: IEA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038096 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0038127 (EC: IDA, PMID: 15133037); GO_0043204 (EC: IEA); GO_0043330 (EC: IEA); GO_0043627 (EC: IEA); GO_0045087 (EC: TAS); GO_0045596 (EC: IEA); GO_0045727 (EC: IEA); GO_0045893 (EC: IEA); GO_0048011 (EC: TAS); GO_0050852 (EC: IEA); GO_0050853 (EC: IEA); GO_0051090 (EC: TAS); GO_0051403 (EC: TAS); GO_0051493 (EC: TAS, PMID: 19565474); GO_0060397 (EC: TAS); GO_0060716 (EC: IEA); GO_0070371 (EC: IDA, PMID: 16314496); GO_0070371 (EC: TAS); GO_0070849 (EC: IDA, PMID: 18794356); GO_0072584 (EC: TAS, PMID: 19565474); GO_0072686 (EC: ISS); GO_0090170 (EC: TAS, PMID: 19565474); GO_2000641 (EC: TAS, PMID: 19565474) PMID: 1319925; 1330687; 1347949; 1378617; 1540184; 1648701; 1712480; 2032290; 7535768; 7566346; 7569900; 7737129; 7768935; 7777512; 7816602; 7876160; 7957875; 8083223; 8157000; 8208531; 8221888; 8248197; 8290275; 8381049; 8384717; 8386592; 8388392; 8389479; 8407983; 8506364; 8552640; 8586671; 8607977; 8618896; 8626561; 8626571; 8631994; 8639570; 8794306; 8806671; 8816480; 8846788; 8900182; 8939914; 8960373; 8994038; 9013873; 9029147; 9030579; 9045910; 9069267; 9092573; 9130707; 9155017; 9199329; 9199504; 9207092; 9211903; 9223324; 9325171; 9335504; 9343414; 9388255; 9403476; 9405468; 9430688; 9440696; 9453574; 9528769; 9535905; 9535909; 9535927; 9558095; 9564043; 9565682; 9592082; 9604935; 9621077; 9628874; 9632734; 9649500; 9658081; 9687510; 9725910; 9744883; 9771888; 9788880; 9792705; 9832145; 9857190; 9858547; 9872331; 9915826; 9973222; 10027715; 10051431; 10066798; 10074203; 10187842; 10194762; 10197981; 10206983; 10207078; 10224087; 10230405; 10318905; 10330152; 10347142; 10371216; 10388555; 10405182; 10409742; 10415025; 10419510; 10446219; 10490027; 10509564; 10521505; 10567572; 10581001; 10617468; 10627507; 10635328; 10644696; 10660621; 10692442; 10702794; 10706702; 10706854; 10712923; 10733581; 10737616; 10747973; 10748182; 10757792; 10762698; 10779345; 10780709; 10799874; 10801826; 10866661; 10878576; 10910078; 10915800; 10942774; 10958679; 10958680; 10958792; 10969079; 10982368; 10988299; 10993892; 10996427; 11013076; 11035004; 11044099; 11114188; 11134045; 11153078; 11157753; 11181841; 11205744; 11226163; 11226259; 11258664; 11260070; 11266467; 11278335; 11278395; 11278799; 11279118; 11279232; 11279280; 11313464; 11350735; 11350938; 11352917; 11358671; 11403955; 11408587; 11409852; 11409876; 11409918; 11416124; 11431474; 11481231; 11489891; 11493009; 11500490; 11504923; 11520933; 11532249; 11549292; 11570821; 11579140; 11581251; 11583024; 11585926; 11606045; 11702783; 11726657; 11741541; 11741894; 11744690; 11748628; 11756441; 11773377; 11776327; 11781324; 11786537; 11788583; 11805108; 11805112; 11823456; 11840291; 11840343; 11857080; 11861509; 11866440; 11866540; 11867630; 11876253; 11878930; 11883936; 11884401; 11891214; 11896055; 11904305; 11914583; 11923300; 11930938; 11937531; 11943771; 11952164; 11958689; 11960991; 11961297; 11971971; 11983899; 11988087; 11994045; 12006497; 12030372; 12032872; 12038794; 12039864; 12048211; 12050114; 12054624; 12058028; 12058067; 12076252; 12077112; 12079429; 12081892; 12081893; 12082090; 12082091; 12082107; 12089333; 12091386; 12093745; 12095140; 12095152; 12105188; 12121974; 12140374; 12149268; 12149431; 12149432; 12151316; 12151396; 12161424; 12167619; 12175859; 12177807; 12183542; 12200131; 12206715; 12218048; 12220502; 12220533; 12226093; 12239168; 12239215; 12351702; 12354773; 12356731; 12356755; 12362243; 12379481; 12387894; 12388423; 12391149; 12393542; 12408764; 12419216; 12435397; 12438317; 12441075; 12444202; 12446729; 12450322; 12456688; 12460991; 12464620; 12473660; 12477932; 12478298; 12482669; 12491158; 12505790; 12508271; 12529294; 12531514; 12536241; 12538349; 12538595; 12540369; 12540563; 12551925; 12555071; 12556484; 12556561; 12562867; 12576315; 12576423; 12592337; 12592382; 12594221; 12603851; 12606501; 12611773; 12618428; 12618431; 12624094; 12637339; 12637502; 12637525; 12643788; 12663671; 12665511; 12665513; 12665801; 12676937; 12682854; 12690112; 12690113; 12697810; 12714584; 12727980; 12734410; 12754301; 12759139; 12760422; 12763138; 12774925; 12775419; 12788955; 12792650; 12794004; 12794087; 12794156; 12801888; 12810719; 12821662; 12826588; 12832284; 12832467; 12837293; 12840032; 12871860; 12883725; 12894225; 12897141; 12917419; 12937136; 12937895; 12943720; 12947314; 12947325; 12957654; 12960100; 12963735; 12972603; 12972619; 12975377; 14500714; 14500727; 14511403; 14530346; 14532121; 14551204; 14551213; 14570886; 14575703; 14581471; 14587029; 14592976; 14602725; 14620918; 14622970; 14634064; 14636584; 14636891; 14654779; 14655753; 14671106; 14672918; 14676207; 14676217; 14676843; 14691575; 14694183; 14701866; 14702039; 14711824; 14714552; 14715628; 14729955; 14742298; 14744867; 14762791; 14764702; 14766231; 14960303; 14968112; 14970210; 14970219; 14985328; 14988395; 14993287; 14997206; 15016620; 15021912; 15030407; 15031289; 15033443; 15033452; 15037631; 15040022; 15041276; 15059773; 15064239; 15068691; 15069082; 15078890; 15081531; 15087455; 15094067; 15116093; 15118098; 15128760; 15128788; 15133037; 15143154; 15155723; 15173068; 15173174; 15184391; 15187168; 15210690; 15210734; 15225643; 15241487; 15243131; 15247230; 15247297; 15249224; 15253667; 15276183; 15292226; 15292252; 15300592; 15322023; 15342917; 15343382; 15347670; 15355986; 15356145; 15358166; 15358203; 15371627; 15379552; 15380617; 15383283; 15459189; 15485655; 15489334; 15489336; 15529758; 15542607; 15542825; 15544353; 15545519; 15557324; 15563472; 15588985; 15592455; 15595556; 15603708; 15610077; 15616014; 15616583; 15632082; 15632084; 15653554; 15654082; 15655247; 15655348; 15664191; 15671028; 15689238; 15699045; 15713638; 15719130; 15721302; 15721486; 15728253; 15728359; 15735702; 15739119; 15746430; 15757891; 15777705; 15778365; 15778391; 15782123; 15809051; 15814736; 15850461; 15851026; 15851480; 15857981; 15861134; 15880942; 15882975; 15890751; 15897893; 15923189; 15928037; 15928662; 15951569; 15952796; 15967790; 15967991; 15979846; 15985432; 16027724; 16039586; 16045329; 16047735; 16051177; 16081426; 16093354; 16094384; 16131083; 16148006; 16149052; 16153436; 16156666; 16198290; 16198352; 16200835; 16209712; 16239230; 16242072; 16242327; 16253958; 16264271; 16273204; 16278291; 16278684; 16280323; 16283431; 16286470; 16287813; 16288922; 16291755; 16314496; 16321971; 16332685; 16368546; 16373414; 16395283; 16395709; 16406609; 16414009; 16436505; 16456540; 16456541; 16492667; 16533805; 16538383; 16539678; 16556602; 16569214; 16574793; 16581800; 16582626; 16611738; 16617096; 16621960; 16624816; 16626623; 16635502; 16636664; 16644735; 16670094; 16687572; 16705745; 16723503; 16735500; 16741963; 16753021; 16763222; 16786433; 16794828; 16796978; 16813525; 16814421; 16820412; 16820791; 16820947; 16848763; 16865246; 16897432; 16912315; 16920714; 16926156; 16941494; 16954218; 16954377; 16980607; 16995340; 16998804; 17015027; 17016429; 17026958; 17035635; 17038630; 17068339; 17068343; 17081983; 17081988; 17105191; 17128418; 17131384; 17142261; 17149612; 17182689; 17192257; 17205132; 17212589; 17215072; 17237147; 17255944; 17255949; 17267664; 17284251; 17284314; 17289590; 17290218; 17294242; 17295209; 17297454; 17303382; 17303384; 17317670; 17317777; 17322878; 17327227; 17341442; 17351113; 17382881; 17388789; 17397260; 17406055; 17410437; 17411366; 17427197; 17443665; 17458890; 17464174; 17469127; 17486076; 17496918; 17498346; 17502994; 17504381; 17510316; 17512500; 17513610; 17519976; 17522999; 17525735; 17526808; 17531530; 17543571; 17550972; 17575262; 17577579; 17581212; 17581316; 17582224; 17583675; 17602748; 17615382; 17620336; 17620599; 17623675; 17624368; 17627030; 17631144; 17634019; 17646929; 17652082; 17652083; 17658605; 17662006; 17667937; 17686614; 17689925; 17693641; 17695723; 17697861; 17701086; 17728396; 17825787; 17850776; 17868650; 17879163; 17881458; 17883418; 17884340; 17889508; 17889855; 17897354; 17906618; 17921324; 17932312; 17933561; 17936667; 17938255; 17942397; 17942603; 17961162; 17974561; 17983270; 17991320; 17991734; 17991743; 18003605; 18006496; 18022816; 18026817; 18029348; 18034864; 18036343; 18045539; 18055485; 18063683; 18065201; 18069631; 18079194; 18079197; 18083711; 18086662; 18087676; 18092356; 18095097; 18160848; 18164958; 18165231; 18165705; 18171912; 18178562; 18182379; 18187448; 18189318; 18204439; 18210145; 18211802; 18212269; 18224451; 18245089; 18245228; 18256791; 18263590; 18266953; 18270969; 18271757; 18276593; 18280112; 18280482; 18280748; 18284542; 18292183; 18296648; 18311544; 18327407; 18328346; 18332145; 18338817; 18358530; 18365874; 18372245; 18378228; 18378312; 18387958; 18400991; 18405916; 18410277; 18414015; 18423386; 18424438; 18424783; 18426801; 18426913; 18434089; 18434324; 18450423; 18456660; 18477477; 18487214; 18490749; 18508762; 18508903; 18509361; 18516291; 18519678; 18535203; 18538010; 18539490; 18559923; 18563362; 18565507; 18567582; 18569454; 18570890; 18572386; 18577518; 18587705; 18593910; 18594198; 18617556; 18624398; 18632853; 18644434; 18667434; 18682391; 18688042; 18692180; 18694962; 18703508; 18710790; 18711316; 18715846; 18729074; 18755896; 18760861; 18760948; 18767165; 18771677; 18781797; 18782768; 18787043; 18787400; 18794356; 18798794; 18802359; 18813840; 18830271; 18848526; 18854243; 18930812; 18949384; 18952847; 18959821; 18977218; 18981248; 19001375; 19008312; 19015316; 19020743; 19032445; 19048100; 19050260; 19060905; 19082453; 19082454; 19091959; 19097033; 19116345; 19147502; 19147767; 19151763; 19152186; 19154323; 19158277; 19164283; 19179479; 19184415; 19199380; 19206162; 19206164; 19211028; 19211765; 19249096; 19287189; 19319478; 19328461; 19363666; 19364816; 19366876; 19385051; 19404844; 19407222; 19414528; 19418584; 19433314; 19445727; 19447520; 19455469; 19457236; 19475568; 19477272; 19477952; 19484147; 19494114; 19496172; 19502238; 19502590; 19505457; 19524666; 19527712; 19531493; 19543489; 19555684; 19565474; 19575782; 19588500; 19589780; 19597469; 19608729; 19610261; 19619936; 19622906; 19628422; 19631649; 19632304; 19633425; 19643177; 19649722; 19650110; 19651986; 19656390; 19672773; 19676104; 19684019; 19686046; 19686845; 19697705; 19713532; 19720761; 19723095; 19729990; 19730683; 19751964; 19755487; 19764561; 19776005; 19782465; 19802003; 19805545; 19808666; 19815047; 19816090; 19816934; 19816936; 19819966; 19822148; 19823867; 19833733; 19835659; 19835973; 19847302; 19855431; 19858308; 19861416; 19874574; 19879846; 19880579; 19901160; 19910580; 19913121; 19914168; 19917255; 19917706; 19919532; 19926313; 19930715; 19941816; 19956840; 20009539; 20019835; 20038816; 20056088; 20056178; 20072156; 20072648; 20074451; 20074637; 20074640; 20075392; 20086178; 20087064; 20093341; 20097574; 20102637; 20103886; 20110267; 20118622; 20123980; 20155832; 20167130; 20174585; 20179103; 20180987; 20189953; 20190820; 20196770; 20201065; 20203690; 20225236; 20226009; 20232314; 20232315; 20307589; 20335309; 20336759; 20351270; 20358251; 20359813; 20371701; 20371703; 20385094; 20386571; 20402410; 20404718; 20406097; 20415541; 20432452; 20434207; 20451919; 20453075; 20455999; 20457808; 20460375; 20463007; 20463008; 20464500; 20467438; 20468064; 20483734; 20490331; 20493910; 20501673; 20506264; 20508983; 20519144; 20538278; 20541731; 20554783; 20566577; 20616308; 20623670; 20628086; 20628624; 20637859; 20655225; 20664595; 20665674; 20671117; 20671123; 20677014; 20680465; 20693286; 20701626; 20716207; 20729213; 20731749; 20735357; 20735841; 20736304; 20737958; 20811691; 20811717; 20823131; 20829350; 20832113; 20837468; 20839920; 20840867; 20842205; 20847405; 20849923; 20853849; 20868224; 20889506; 20889557; 20932473; 20936779; 20956553; 20965228; 20974803; 21029458; 21029675; 21057728; 21070506; 21071439; 21076047; 21079800; 21084381; 21088106; 21098038; 21098700; 21110948; 21123621; 21126445; 21135229; 21139048; 21143918; 21147777; 21150201; 21159167; 21164364; 21172429; 21172820; 21177334; 21181091; 21185392; 21199725; 21200133; 21205481; 21205837; 21212516; 21212994; 21224381; 21228323; 21251657; 21262199; 21262770; 21264233; 21266192; 21278199; 21285250; 21293101; 21321112; 21325048; 21335558; 21336309; 21349701; 21354100; 21354279; 21356304; 21368226; 21368234; 21370247; 21378396; 21388279; 21413023; 21415216; 21423810; 21424124; 21444628; 21448845; 21454057; 21454500; 21454579; 21454676; 21454801; 21474333; 21483469; 21487005; 21497119; 21520151; 21537329; 21541441; 21548882; 21551235; 21559503; 21562093; 21565167; 21566292; 21567396; 21574189; 21586573; 21606674; 21607585; 21618303; 21619869; 21625939; 21628073; 21635820; 21641389; 21645924; 21651489; 21655091; 21669399; 21675959; 21680106; 21707777; 21708241; 21713404; 21715333; 21720547; 21729547; 21730285; 21732279; 21738584; 21738699; 21742938; 21745501; 21747041; 21747198; 21752354; 21760921; 21762808; 21763495; 21765462; 21768093; 21768115; 21768338; 21778192; 21803177; 21807114; 21808062; 21811066; 21821233; 21821885; 21826244; 21833088; 21833774; 21835307; 21840940; 21842857; 21849556; 21852536; 21865167; 21871886; 21873423; 21873429; 21875946; 21878648; 21890473; 21896986; 21899882; 21906983; 21908610; 21914806; 21917714; 21925842; 21930785; 21952366; 21959954; 21959987; 21960346; 21961242; 21987775; 21988832; 21989417; 22009749; 22024154; 22025613; 22028271; 22028468; 22033920; 22039048; 22039051; 22052014; 22065579; 22075507; 22076613; 22090124; 22094458; 22105580; 22114354; 22117074; 22123847; 22147898; 22158075; 22162761; 22171261; 22174934; 22178882; 22200507; 22222560; 22229442; 22238304; 22239058; 22241220; 22243975; 22246186; 22262799; 22265030; 22271254; 22277029; 22293503; 22328529; 22344067; 22344606; 22345558; 22347375; 22354461; 22354961; 22362758; 22370345; 22388352; 22393163; 22406505; 22407921; 22447027; 22475145; 22475441; 22479424; 22487967; 22493490; 22502979; 22504224; 22504301; 22505724; 22521293; 22526456; 22537555; 22543708; 22546605; 22551942; 22553998; 22556124; 22560877; 22562654; 22563495; 22563497; 22564243; 22574813; 22575864; 22584435; 22593617; 22658382; 22659165; 22670315; 22672288; 22675204; 22696230; 22702503; 22712802; 22722337; 22735594; 22751010; 22751131; 22778266; 22791812; 22796164; 22808094; 22808218; 22808266; 22820249; 22825757; 22828925; 22842575; 22848708; 22864777; 22865467; 22866973; 22869729; 22871965; 22898922; 22902213; 22904195; 22914360; 22914643; 22917644; 22927430; 22935974; 22937208; 22939629; 22955283; 22955917; 22990118; 23012423; 23022380; 23024368; 23039362; 23048032; 23052192; 23066034; 23076151; 23088735; 23098854; 23115159; 23125486; 23128233; 23174997; 23183114; 23196978; 23207287; 23222305; 23247634; 23250869; 23258237; 23265704; 23282009; 23306155; 23332156; 23338561; 23338717; 23341459; 23349307; 23349819; 23357054; 23360766; 23383273; 23424616; 23430108; 23434428; 23441482; 23447674; 23455922; 23457635; 23468892; 23479736; 23516513; 23519423; 23535064; 23537502; 23549785; 23555182; 23558220; 23569008; 23575685; 23576434; 23584453; 23585396; 23589880; 23591790; 23602568; 23613227; 23615537; 23618859; 23620784; 23621408; 23621870; 23640488; 23645677; 23651922; 23671702; 23674093; 23677697; 23704935; 23709326; 23727019; 23754287; 23776205; 23806683; 23806693; 23812726; 23827636; 23845703; 23847209; 23867452; 23888996; 23923067; 23983265; 24091658; 24128853; 24161842; 24164897; 24166600; 24183461; 24291038; 24370825 mitogen-activated protein kinase 1 Ensembl:ENSG00000100030 HGNC:6871 HPRD:01496 MIM:176948 Vega:OTTHUMG00000030508 MAPK1 Bin Zhao, Yue Liu, Oliver He ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK WEB: http://www.ncbi.nlm.nih.gov/gene MAPK3 mitogen-activated protein kinase 3 5595 16p11.2 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0000165 (EC: NAS); GO_0000165 (EC: TAS); GO_0000186 (EC: TAS); GO_0000187 (EC: TAS); GO_0001784 (EC: IEA); GO_0001934 (EC: IMP, PMID: 19664780); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004707 (EC: IDA, PMID: 8388392); GO_0004707 (EC: NAS, PMID: 7687743); GO_0004707 (EC: TAS); GO_0005515 (EC: IPI, PMID: 10066421); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005634 (EC: TAS, PMID: 19565474); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005739 (EC: TAS, PMID: 19565474); GO_0005769 (EC: TAS, PMID: 19565474); GO_0005770 (EC: TAS, PMID: 19565474); GO_0005794 (EC: TAS, PMID: 19565474); GO_0005829 (EC: TAS, PMID: 19565474); GO_0005856 (EC: TAS, PMID: 19565474); GO_0005901 (EC: TAS, PMID: 19565474); GO_0005925 (EC: TAS, PMID: 19565474); GO_0006360 (EC: TAS); GO_0006361 (EC: TAS); GO_0006468 (EC: IDA, PMID: 7687743); GO_0006915 (EC: IEA); GO_0006975 (EC: IDA, PMID: 17560175); GO_0007049 (EC: IEA); GO_0007173 (EC: TAS); GO_0007264 (EC: TAS); GO_0007265 (EC: TAS); GO_0007411 (EC: TAS); GO_0007596 (EC: TAS); GO_0008286 (EC: TAS); GO_0008543 (EC: TAS); GO_0009887 (EC: IEA); GO_0010467 (EC: TAS); GO_0015630 (EC: IDA); GO_0016032 (EC: IEA); GO_0016310 (EC: IDA, PMID: 15950189); GO_0019221 (EC: TAS); GO_0019233 (EC: IEA); GO_0019902 (EC: IPI, PMID: 19494114); GO_0030168 (EC: TAS); GO_0030509 (EC: IMP, PMID: 19664780); GO_0031143 (EC: IEA); GO_0031663 (EC: IEA); GO_0032872 (EC: TAS, PMID: 19565474); GO_0033129 (EC: IMP); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035066 (EC: IMP); GO_0035666 (EC: TAS); GO_0038083 (EC: IDA, PMID: 8388392); GO_0038095 (EC: TAS); GO_0038096 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0043330 (EC: IEA); GO_0045087 (EC: TAS); GO_0045944 (EC: IMP); GO_0048011 (EC: TAS); GO_0051090 (EC: TAS); GO_0051216 (EC: IEA); GO_0051403 (EC: TAS); GO_0051493 (EC: TAS, PMID: 19565474); GO_0060397 (EC: TAS); GO_0070374 (EC: IMP, PMID: 19664780); GO_0070498 (EC: IMP); GO_0070849 (EC: IDA, PMID: 18794356); GO_0071260 (EC: IEP, PMID: 19593445); GO_0072584 (EC: TAS, PMID: 19565474); GO_0090170 (EC: TAS, PMID: 19565474); GO_2000641 (EC: TAS, PMID: 19565474); GO_2000657 (EC: IEA) PMID: 862676; 1319925; 1322499; 1347949; 1463607; 1540184; 1922387; 7535768; 7687743; 7739560; 7836374; 8112321; 8152805; 8197172; 8208531; 8226933; 8290275; 8325880; 8376365; 8388392; 8407983; 8423803; 8506364; 8552640; 8618896; 8626571; 8626767; 8631994; 8632909; 8639570; 8794306; 8806671; 8939914; 8940068; 9006895; 9020136; 9054461; 9069267; 9126608; 9130707; 9155018; 9211903; 9218456; 9223324; 9235954; 9325171; 9343414; 9388255; 9403476; 9446616; 9525956; 9535905; 9535909; 9535927; 9558095; 9564043; 9621077; 9628824; 9658081; 9687510; 9733512; 9792677; 9792705; 9857190; 9872331; 9915826; 10027715; 10066421; 10074203; 10187842; 10194762; 10206983; 10224087; 10339476; 10347142; 10383391; 10402467; 10415025; 10419510; 10431817; 10446219; 10509564; 10521505; 10551817; 10559944; 10570282; 10574913; 10581001; 10597297; 10617468; 10627507; 10635328; 10648599; 10677502; 10702794; 10712923; 10725920; 10727525; 10748187; 10780709; 10799874; 10869359; 10912793; 10915800; 10958792; 10982368; 11027280; 11044099; 11114188; 11131153; 11134045; 11135364; 11205744; 11226163; 11260070; 11278799; 11279232; 11287604; 11342557; 11350938; 11387337; 11403955; 11409852; 11409918; 11466319; 11504923; 11520933; 11532249; 11551945; 11570821; 11579140; 11581251; 11583024; 11585926; 11682603; 11702783; 11741541; 11741977; 11773377; 11776327; 11781324; 11784715; 11788583; 11792123; 11866440; 11866540; 11884401; 11891214; 11904305; 11923300; 11930938; 11937531; 11948414; 11952164; 11960991; 11961297; 11986622; 11988087; 12030372; 12032872; 12048211; 12049732; 12063245; 12081892; 12082090; 12082091; 12089333; 12095152; 12118371; 12121974; 12167619; 12183542; 12193595; 12200131; 12218048; 12226077; 12239168; 12356731; 12362243; 12388423; 12408764; 12441075; 12446729; 12456688; 12473660; 12477932; 12482669; 12491158; 12529294; 12531514; 12538349; 12538595; 12540563; 12555071; 12562867; 12576423; 12594221; 12603851; 12606501; 12624094; 12624098; 12637339; 12637502; 12637525; 12643788; 12663671; 12676937; 12682854; 12689928; 12690112; 12697810; 12727216; 12754301; 12759139; 12763138; 12775419; 12792650; 12794156; 12810719; 12821662; 12832284; 12832467; 12840032; 12937136; 12943720; 12947325; 12960100; 12975377; 14499342; 14515181; 14530346; 14532121; 14551213; 14559906; 14575703; 14587029; 14592976; 14602725; 14622970; 14634064; 14651992; 14671106; 14676207; 14676217; 14701866; 14702039; 14711824; 14712216; 14714552; 14744867; 14960303; 14985328; 14988395; 15016620; 15030407; 15040022; 15059773; 15064239; 15068691; 15069082; 15078890; 15081531; 15113754; 15118098; 15128760; 15133517; 15143154; 15144186; 15173068; 15184391; 15210690; 15210734; 15243131; 15247230; 15247297; 15249224; 15256218; 15276183; 15292176; 15302935; 15321994; 15322023; 15336571; 15342917; 15347670; 15355986; 15356145; 15364926; 15371627; 15379552; 15469820; 15471881; 15489334; 15509801; 15542825; 15544353; 15545519; 15563472; 15588985; 15603708; 15616583; 15642734; 15653554; 15655247; 15655348; 15671028; 15689238; 15721302; 15721486; 15728253; 15735702; 15739119; 15746430; 15757891; 15778365; 15782123; 15784503; 15809051; 15814736; 15861134; 15878863; 15879168; 15880942; 15890751; 15919053; 15923189; 15950189; 15951569; 15967790; 15967991; 15985432; 16047735; 16050810; 16081426; 16149052; 16153436; 16156742; 16209712; 16239230; 16242072; 16253958; 16273281; 16278291; 16278684; 16280323; 16287813; 16291755; 16317051; 16321971; 16332685; 16344560; 16368546; 16373414; 16395283; 16406609; 16414009; 16428339; 16436505; 16456541; 16461926; 16492667; 16515552; 16533948; 16538383; 16539678; 16556602; 16569214; 16574793; 16580177; 16581800; 16582626; 16617096; 16621960; 16624816; 16626623; 16644735; 16670094; 16687572; 16699726; 16705745; 16735500; 16741963; 16794828; 16796978; 16810323; 16813525; 16814421; 16820412; 16820791; 16844778; 16849642; 16920714; 16926156; 16941494; 16954218; 16990258; 16995340; 16998804; 17016429; 17035635; 17068339; 17068343; 17081983; 17131384; 17142261; 17149612; 17182689; 17192257; 17209045; 17212589; 17215072; 17237147; 17237423; 17255949; 17267664; 17273789; 17274723; 17290218; 17294242; 17297454; 17303382; 17303384; 17311928; 17317670; 17322878; 17341442; 17351113; 17382881; 17388789; 17406055; 17410437; 17411366; 17427197; 17443665; 17453826; 17458890; 17464174; 17478078; 17496918; 17504381; 17510316; 17513610; 17519976; 17522999; 17525735; 17526808; 17543571; 17560175; 17565009; 17575262; 17581212; 17582224; 17583675; 17615382; 17620336; 17622743; 17627030; 17634019; 17644078; 17652082; 17662006; 17686614; 17695723; 17728396; 17825787; 17850776; 17868650; 17879163; 17881458; 17884340; 17889508; 17889855; 17897354; 17906618; 17921324; 17932312; 17936667; 17938255; 17942397; 17942603; 17967787; 17983270; 17991320; 17991743; 18006496; 18022816; 18029348; 18034864; 18036343; 18055485; 18063683; 18065201; 18070930; 18079194; 18079197; 18086557; 18086662; 18087676; 18092356; 18095097; 18160848; 18164958; 18165705; 18166657; 18174382; 18187448; 18189318; 18210145; 18212269; 18224451; 18245089; 18245228; 18263590; 18266953; 18270969; 18271757; 18276593; 18280112; 18280482; 18280748; 18284542; 18288130; 18292183; 18296648; 18327407; 18328346; 18332145; 18358530; 18365874; 18372245; 18378312; 18387958; 18398416; 18405916; 18410277; 18414015; 18423386; 18424438; 18424783; 18426801; 18426913; 18433299; 18434089; 18434324; 18448488; 18463290; 18477477; 18487214; 18508903; 18516291; 18535203; 18538010; 18559923; 18563362; 18570890; 18572386; 18577518; 18593910; 18617556; 18624398; 18632853; 18644434; 18660489; 18667434; 18682391; 18688042; 18691388; 18692180; 18694962; 18703508; 18710790; 18711316; 18715846; 18755896; 18760861; 18771677; 18787043; 18787400; 18794356; 18830271; 18853184; 18854243; 18854640; 18949384; 18981248; 18983981; 18986987; 19008312; 19015316; 19020743; 19032445; 19035465; 19060905; 19082454; 19091959; 19097033; 19116345; 19147502; 19147767; 19153083; 19154323; 19158277; 19160418; 19164129; 19164283; 19167335; 19184415; 19199380; 19206162; 19242545; 19266047; 19298651; 19319745; 19328461; 19363666; 19366876; 19404844; 19407222; 19414528; 19418584; 19428994; 19445727; 19447520; 19453261; 19455469; 19457236; 19477952; 19494114; 19502238; 19502590; 19543489; 19565474; 19575782; 19588500; 19589780; 19593445; 19597469; 19608729; 19610261; 19619936; 19622906; 19631608; 19632304; 19643177; 19649722; 19651986; 19656390; 19664780; 19666073; 19672022; 19676104; 19684019; 19686845; 19697705; 19713532; 19723095; 19729990; 19751964; 19776005; 19777442; 19782465; 19802003; 19805545; 19808666; 19815047; 19816090; 19816934; 19816936; 19819966; 19822148; 19823867; 19828458; 19833733; 19834610; 19835659; 19847302; 19855431; 19858308; 19861416; 19874574; 19895547; 19910486; 19910580; 19917255; 19917706; 19919532; 19926313; 19930715; 19956840; 20009539; 20016498; 20019835; 20028985; 20038816; 20056088; 20069553; 20072648; 20074451; 20074637; 20074640; 20075392; 20087064; 20097574; 20102637; 20103886; 20123980; 20126471; 20126615; 20155832; 20164223; 20167130; 20174585; 20179103; 20180987; 20189953; 20190820; 20201065; 20203690; 20225236; 20231899; 20232314; 20232315; 20307589; 20335309; 20336759; 20351270; 20358251; 20359813; 20371703; 20385094; 20386571; 20402410; 20404718; 20406097; 20432452; 20451919; 20453075; 20460375; 20463007; 20463008; 20464500; 20483734; 20490331; 20493910; 20501673; 20506264; 20512084; 20519144; 20538278; 20566577; 20616308; 20622900; 20637859; 20664595; 20671117; 20671123; 20680465; 20693286; 20701626; 20716207; 20726858; 20729213; 20731749; 20735357; 20735841; 20736304; 20737958; 20811691; 20811717; 20823131; 20829350; 20837468; 20839920; 20840867; 20842205; 20849923; 20853849; 20868224; 20889506; 20889557; 21029458; 21057728; 21070506; 21071439; 21076047; 21079800; 21084381; 21123621; 21126445; 21135229; 21139048; 21147777; 21150201; 21152870; 21159167; 21172820; 21185392; 21187340; 21199725; 21209852; 21212994; 21228323; 21262199; 21262770; 21270289; 21273059; 21278199; 21285250; 21293101; 21321112; 21325048; 21335558; 21349701; 21354279; 21368226; 21370247; 21378313; 21413023; 21423810; 21444628; 21448845; 21454500; 21454579; 21474332; 21474333; 21483469; 21487005; 21520151; 21537329; 21541441; 21551235; 21574189; 21606674; 21607585; 21625939; 21635820; 21645924; 21669399; 21675959; 21687944; 21708241; 21713404; 21730054; 21730285; 21732279; 21742938; 21747041; 21750416; 21752354; 21760921; 21764057; 21765462; 21768093; 21768115; 21772273; 21778192; 21803177; 21816898; 21821233; 21833774; 21840940; 21852536; 21871886; 21873423; 21873429; 21875946; 21878648; 21890473; 21899882; 21900206; 21906983; 21908610; 21910869; 21914806; 21917714; 21925842; 21952366; 21959954; 21960346; 21963094; 21989417; 22009749; 22024154; 22025613; 22028271; 22028468; 22039050; 22039051; 22052014; 22076613; 22076920; 22090124; 22094458; 22117074; 22123847; 22147898; 22158075; 22162761; 22171261; 22174934; 22178882; 22222560; 22229442; 22238304; 22265030; 22277029; 22293503; 22344067; 22344606; 22362758; 22370345; 22384111; 22388352; 22393163; 22396784; 22406505; 22407921; 22465663; 22479424; 22487967; 22502979; 22504224; 22505724; 22543708; 22551942; 22553998; 22556124; 22560877; 22562654; 22563495; 22563497; 22564243; 22574813; 22593617; 22672288; 22696230; 22702503; 22712802; 22722337; 22735594; 22796164; 22808094; 22808266; 22828925; 22848708; 22865467; 22866973; 22869729; 22898922; 22902213; 22904195; 22914360; 22914643; 22917644; 22927430; 22935974; 22937208; 22939629; 22955917; 22990118; 22995914; 23000965; 23012423; 23024368; 23076151; 23088735; 23098854; 23166842; 23174997; 23222305; 23247634; 23258237; 23265704; 23274199; 23306155; 23319595; 23332156; 23341459; 23349307; 23357054; 23360766; 23383273; 23408424; 23424616; 23430108; 23441482; 23449627; 23457635; 23468892; 23516513; 23549785; 23558220; 23569008; 23576434; 23585396; 23589880; 23602568; 23613227; 23615537; 23618859; 23620784; 23621408; 23621870; 23640488; 23645677; 23651922; 23671702; 23677697; 23684072; 23709326; 23754287; 23776205; 23806683; 23806693; 23812726; 23827636; 23847209; 23867452; 24161842; 24164897; 24166600; 24183461; 24291038; 24370825 mitogen-activated protein kinase 3 Ensembl:ENSG00000102882 HGNC:6877 HPRD:03479 MIM:601795 Vega:OTTHUMG00000132149 MAPK3 Bin Zhao, Yue Liu, Oliver He JNK JNK-46 JNK1 JNK1A2 JNK21B1/2 PRKM8 SAPK1 SAPK1c WEB: http://www.ncbi.nlm.nih.gov/gene MAPK8 mitogen-activated protein kinase 8 5599 10q11.22 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0001503 (EC: IEA); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004674 (EC: IDA, PMID: 14967141); GO_0004705 (EC: IDA); GO_0005515 (EC: IPI, PMID: 10393177); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005739 (EC: IEA); GO_0005829 (EC: TAS); GO_0006915 (EC: TAS); GO_0006950 (EC: TAS, PMID: 8137421); GO_0007254 (EC: IDA, PMID: 8654373); GO_0007254 (EC: TAS); GO_0007258 (EC: IDA, PMID: 14967141); GO_0009411 (EC: IDA, PMID: 14967141); GO_0010628 (EC: IMP); GO_0018105 (EC: IDA, PMID: 15850461); GO_0018107 (EC: IDA); GO_0018107 (EC: IMP); GO_0031063 (EC: IMP); GO_0032091 (EC: IDA); GO_0032880 (EC: IDA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035033 (EC: IMP); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042826 (EC: IPI); GO_0043065 (EC: TAS); GO_0043066 (EC: IDA, PMID: 14967141); GO_0045087 (EC: TAS); GO_0046686 (EC: IEA); GO_0048011 (EC: TAS); GO_0051090 (EC: TAS); GO_0051403 (EC: TAS); GO_0071260 (EC: IEP, PMID: 19593445); GO_0090045 (EC: IMP); GO_0097190 (EC: TAS); GO_0097193 (EC: TAS); GO_1900740 (EC: TAS); GO_2000017 (EC: IEA); GO_2001235 (EC: IEA) PMID: 1748630; 7535770; 7642542; 7737129; 7737130; 7839144; 8001819; 8137421; 8177321; 8224842; 8586671; 8621542; 8632909; 8654373; 8846788; 8917518; 9020136; 9030579; 9045910; 9129988; 9162092; 9195981; 9199329; 9199504; 9207092; 9211903; 9223324; 9235954; 9343414; 9374537; 9393873; 9396779; 9399639; 9403476; 9405400; 9405416; 9520479; 9575168; 9621077; 9661668; 9670954; 9692890; 9724739; 9732264; 9733513; 9774977; 9788880; 9808624; 9851932; 9872331; 9889198; 10187783; 10346818; 10357815; 10383391; 10391943; 10393177; 10394361; 10419510; 10446219; 10471813; 10490659; 10509564; 10521505; 10523642; 10551811; 10567572; 10585392; 10597297; 10601313; 10629060; 10713157; 10722755; 10747973; 10756100; 10797012; 10799874; 10856240; 10878576; 10912793; 10913135; 10962563; 11042694; 11057897; 11062067; 11108663; 11153078; 11238452; 11260070; 11278395; 11278789; 11278799; 11279118; 11279197; 11279232; 11283254; 11323415; 11350938; 11387337; 11408587; 11432831; 11448159; 11468147; 11479302; 11489891; 11504923; 11517249; 11525649; 11551945; 11566021; 11602244; 11606564; 11698270; 11700324; 11707464; 11749722; 11781324; 11788583; 11865055; 11912216; 11931768; 11944898; 11948398; 11971973; 11983683; 11988087; 12023963; 12039864; 12052834; 12058026; 12058028; 12079429; 12089333; 12095152; 12097334; 12121974; 12135322; 12138158; 12140754; 12143039; 12148599; 12167088; 12171600; 12185592; 12189133; 12206715; 12223491; 12225289; 12228228; 12239168; 12242293; 12296995; 12351658; 12351702; 12354774; 12359245; 12376548; 12391307; 12413764; 12417588; 12421945; 12477932; 12478662; 12514174; 12538493; 12576423; 12591950; 12592382; 12646240; 12646564; 12659851; 12689591; 12697749; 12707267; 12714584; 12734330; 12756254; 12763138; 12775419; 12787561; 12788955; 12804775; 12810082; 12818176; 12821118; 12847227; 12853963; 12857973; 12859962; 12874243; 12878610; 12902351; 12917434; 12958075; 12960231; 12963725; 13130464; 14500675; 14500727; 14504284; 14514687; 14517282; 14532003; 14551213; 14557276; 14561739; 14572659; 14597672; 14612408; 14633987; 14637155; 14688370; 14699155; 14701702; 14701799; 14702039; 14724588; 14729602; 14764673; 14766760; 14967141; 14981905; 15013949; 15169762; 15184502; 15225643; 15238629; 15246824; 15276183; 15299005; 15302935; 15326485; 15334056; 15345747; 15383283; 15456887; 15474087; 15483136; 15516492; 15527495; 15528994; 15538975; 15542843; 15569856; 15590691; 15603708; 15629131; 15637062; 15655348; 15657352; 15659383; 15665513; 15677475; 15688026; 15693750; 15696159; 15721744; 15722200; 15733859; 15749833; 15755722; 15769735; 15778365; 15778501; 15827086; 15850461; 15857981; 15860507; 15890690; 15958389; 15979846; 15981086; 15998799; 16007099; 16038800; 16086581; 16105650; 16153436; 16157600; 16166642; 16176806; 16243842; 16260419; 16260609; 16264271; 16282329; 16283431; 16291755; 16307741; 16321971; 16328781; 16339571; 16344560; 16381010; 16395283; 16407310; 16412424; 16434970; 16446428; 16465391; 16481105; 16533805; 16539678; 16549498; 16569638; 16581800; 16611996; 16636664; 16648634; 16687404; 16699726; 16740711; 16760468; 16794185; 16802349; 16810318; 16814421; 16815888; 16824735; 16895791; 16912864; 16927023; 16972261; 16983342; 17008315; 17023523; 17054907; 17074809; 17079291; 17145805; 17158878; 17178870; 17189706; 17192257; 17255354; 17296730; 17303384; 17317777; 17363973; 17453826; 17478078; 17481915; 17496921; 17541429; 17545598; 17568996; 17584736; 17603935; 17620321; 17626013; 17640761; 17652454; 17690186; 17693927; 17699782; 17702750; 17703233; 17704768; 17719653; 17785464; 17875713; 17883418; 17904874; 17908987; 17913539; 17933493; 17942603; 17967471; 17982228; 18003900; 18025271; 18036196; 18055217; 18082745; 18086557; 18087676; 18094581; 18160848; 18164704; 18181766; 18199680; 18212053; 18218857; 18219313; 18249102; 18253836; 18256527; 18276794; 18286207; 18288129; 18292600; 18293403; 18297686; 18316600; 18316603; 18325654; 18337589; 18344085; 18348163; 18356158; 18373696; 18387958; 18401423; 18405916; 18429822; 18439101; 18457359; 18495129; 18506470; 18524773; 18540881; 18541008; 18547751; 18570871; 18573678; 18594007; 18603327; 18620777; 18636174; 18651223; 18663379; 18667537; 18681908; 18682391; 18703151; 18713649; 18713996; 18718914; 18723442; 18757369; 18769111; 18782768; 18813780; 18815275; 18818208; 18845538; 18922473; 18936517; 18950845; 18957422; 18978303; 18979912; 18982452; 18989785; 18996088; 19033664; 19036714; 19037093; 19041150; 19052872; 19056926; 19060920; 19069644; 19071215; 19074436; 19097143; 19153595; 19154785; 19159663; 19166930; 19168796; 19194824; 19204086; 19206162; 19234442; 19245816; 19248119; 19270716; 19275580; 19286999; 19287189; 19319745; 19339050; 19351724; 19352384; 19418584; 19424800; 19454725; 19468799; 19478459; 19479051; 19523467; 19527717; 19567513; 19570911; 19574423; 19589256; 19593445; 19596001; 19604147; 19616043; 19620725; 19638579; 19651615; 19664626; 19667122; 19676104; 19686584; 19690982; 19693773; 19695707; 19723092; 19723627; 19748889; 19778898; 19782079; 19801633; 19802005; 19803394; 19806201; 19815509; 19822148; 19822666; 19859790; 19862774; 19864026; 19877043; 19893453; 19900593; 19901160; 19910486; 19913121; 19923798; 19937141; 19940138; 19940360; 19966288; 19995557; 19996270; 20018857; 20027304; 20051532; 20056178; 20056910; 20060003; 20069553; 20070836; 20070945; 20074375; 20086174; 20088952; 20102411; 20103647; 20116378; 20130137; 20133937; 20138424; 20139358; 20142324; 20145041; 20150185; 20156194; 20173753; 20194509; 20225236; 20336759; 20371626; 20380698; 20432452; 20450729; 20452983; 20457808; 20483637; 20483734; 20490718; 20495362; 20510162; 20511226; 20512919; 20512932; 20525557; 20551953; 20566643; 20573157; 20581839; 20622336; 20628086; 20632440; 20647313; 20648623; 20680486; 20717968; 20732415; 20735357; 20829350; 20870032; 20878914; 20919940; 20944115; 20960177; 21106355; 21122381; 21123173; 21134350; 21139048; 21145111; 21148294; 21148313; 21152872; 21156789; 21172010; 21172429; 21187925; 21191018; 21212517; 21223552; 21237154; 21362231; 21364631; 21364637; 21368226; 21378396; 21384452; 21439937; 21444723; 21454558; 21465527; 21483469; 21483669; 21504622; 21511059; 21524306; 21526344; 21629969; 21651489; 21660049; 21697181; 21719561; 21729547; 21752354; 21757743; 21764057; 21768777; 21775054; 21806545; 21817106; 21822690; 21832049; 21856198; 21863240; 21900206; 21906983; 21930785; 21931671; 21943220; 21948112; 21959987; 21964465; 21984578; 21988832; 22005259; 22014979; 22021110; 22087220; 22100391; 22110360; 22114267; 22154358; 22164242; 22171160; 22184250; 22283740; 22327296; 22351776; 22357202; 22363806; 22394200; 22433870; 22435755; 22446103; 22447977; 22450687; 22456510; 22493283; 22493490; 22505724; 22506718; 22509080; 22689214; 22729748; 22749438; 22763043; 22766602; 22844345; 22850273; 22870247; 22902540; 22920299; 23020677; 23051914; 23056263; 23077074; 23237571; 23258237; 23273084; 23290789; 23326144; 23359252; 23393199; 23416355; 23440494; 23580093; 23602568; 23603344; 23608488; 23608534; 23615449; 23662689; 23712703; 23715767; 23770673; 23861391; 23906792; 23916702; 24023291; 24055030; 24091673; 24184208; 24225136 mitogen-activated protein kinase 8 Ensembl:ENSG00000107643 HGNC:6881 HPRD:03100 MIM:601158 Vega:OTTHUMG00000018172 MAPK8 Bin Zhao, Yue Liu, Oliver He P38B P38BETA2 PRKM11 SAPK2 SAPK2B p38-2 p38Beta WEB: http://www.ncbi.nlm.nih.gov/gene MAPK11 mitogen-activated protein kinase 11 5600 22q13.33 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0000187 (EC: TAS); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004674 (EC: TAS); GO_0004707 (EC: IDA, PMID: 10330143); GO_0005515 (EC: IPI, PMID: 17254968); GO_0005524 (EC: IEA); GO_0005654 (EC: TAS); GO_0005829 (EC: TAS); GO_0006351 (EC: IEA); GO_0006950 (EC: IDA, PMID: 8663524); GO_0007165 (EC: TAS, PMID: 8663524); GO_0007265 (EC: TAS); GO_0010467 (EC: TAS); GO_0016070 (EC: TAS); GO_0016071 (EC: TAS); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035556 (EC: IDA, PMID: 8663524); GO_0035666 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042692 (EC: TAS); GO_0045087 (EC: TAS); GO_0048011 (EC: TAS); GO_0051090 (EC: TAS); GO_0051149 (EC: TAS); GO_0051403 (EC: TAS) PMID: 8663524; 9029150; 9199504; 9207191; 9218798; 9235954; 9430721; 9628874; 9632706; 9687510; 9832563; 10201954; 10207622; 10330143; 10362531; 10391889; 10591208; 10608813; 10744763; 10782990; 10811012; 10820433; 10878576; 10952989; 11154262; 11162833; 11211234; 11359773; 11448946; 11495898; 11551945; 11579095; 11847341; 12171600; 12239168; 12384504; 12454855; 12475989; 12477932; 12510156; 12586546; 12761180; 14522966; 14557269; 14651992; 14680475; 14688370; 14724572; 15048855; 15249224; 15273249; 15304097; 15304344; 15326477; 15356147; 15461802; 15489334; 15708845; 15728454; 15923648; 16120828; 16341674; 16643845; 16966330; 17241234; 17254968; 17380123; 17906618; 18192325; 18950637; 19082897; 19622861; 19706373; 19913121; 20053787; 20056178; 20110267; 20162623; 20188673; 20378550; 20626350; 20628086; 20724307; 21757713; 21832049; 21900206; 21911485; 21988832; 22157753; 22515544; 22522454; 23602568; 23625915; 23824909 mitogen-activated protein kinase 11 Ensembl:ENSG00000185386 HGNC:6873 HPRD:04208 MIM:602898 Vega:OTTHUMG00000150226 MAPK11 Bin Zhao, Yue Liu, Oliver He MAPK 13 MAPK-13 PRKM13 SAPK4 p38delta WEB: http://www.ncbi.nlm.nih.gov/gene MAPK13 mitogen-activated protein kinase 13 5603 RP1-179N16.4 6p21.31 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000165 (EC: IDA, PMID: 9218798); GO_0004674 (EC: IDA, PMID: 12244047); GO_0004707 (EC: IDA, PMID: 9218798); GO_0005515 (EC: IPI, PMID: 19135240); GO_0005524 (EC: IEA); GO_0005829 (EC: TAS); GO_0006351 (EC: IEA); GO_0006355 (EC: IEA); GO_0006950 (EC: IDA, PMID: 9218798); GO_0006970 (EC: IDA, PMID: 9731215); GO_0007049 (EC: IEA); GO_0007265 (EC: TAS); GO_0018105 (EC: IDA, PMID: 15850461); GO_0032755 (EC: IMP, PMID: 19279008); GO_0035556 (EC: IDA, PMID: 9218798); GO_0048011 (EC: TAS); GO_0050729 (EC: IC, PMID: 19279008) PMID: 8125298; 9199504; 9207191; 9218798; 9295308; 9297626; 9374491; 9628874; 9731215; 9841871; 10066767; 10201954; 10727080; 11378392; 11500363; 11520933; 12080077; 12171600; 12239168; 12244047; 12477932; 12482858; 12810719; 14574404; 15231748; 15340077; 15489334; 15850461; 16344560; 16644870; 16751776; 17906618; 18367666; 18559936; 18624398; 19135240; 19279008; 19816939; 19913121; 20056178; 20090411; 20478268; 20628086; 20804750; 20805296; 21832049; 21906983; 21988832; 22199349; 22730327; 23187130; 23383273; 23590314; 23602568; 23722928; 23798682; 23878395 mitogen-activated protein kinase 13 Ensembl:ENSG00000156711 HGNC:6875 HPRD:09113 MIM:602899 Vega:OTTHUMG00000014587 MAPK13 Bin Zhao, Yue Liu, Oliver He CFC3 MAPKK1 MEK1 MKK1 PRKMK1 WEB: http://www.ncbi.nlm.nih.gov/gene MAP2K1 mitogen-activated protein kinase kinase 1 5604 15q22.1-q22.33 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0000165 (EC: TAS); GO_0000186 (EC: TAS); GO_0000187 (EC: TAS, PMID: 19565474); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0003056 (EC: IEA); GO_0004672 (EC: TAS, PMID: 10570282); GO_0004674 (EC: TAS); GO_0004708 (EC: IDA, PMID: 8388392); GO_0004712 (EC: TAS, PMID: 19565474); GO_0004713 (EC: IEA); GO_0004728 (EC: IEA); GO_0005515 (EC: IPI, PMID: 15299019); GO_0005524 (EC: IEA); GO_0005634 (EC: TAS, PMID: 19565474); GO_0005737 (EC: IDA); GO_0005739 (EC: TAS, PMID: 19565474); GO_0005769 (EC: TAS, PMID: 19565474); GO_0005770 (EC: TAS, PMID: 19565474); GO_0005794 (EC: TAS, PMID: 19565474); GO_0005816 (EC: IEA); GO_0005829 (EC: TAS, PMID: 19565474); GO_0005886 (EC: IDA); GO_0005925 (EC: TAS, PMID: 19565474); GO_0005938 (EC: IEA); GO_0006928 (EC: TAS, PMID: 10912793); GO_0006935 (EC: TAS, PMID: 10570282); GO_0006979 (EC: IEA); GO_0007050 (EC: IMP, PMID: 9765203); GO_0007067 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10570282); GO_0007173 (EC: TAS); GO_0007264 (EC: TAS); GO_0007265 (EC: TAS); GO_0007411 (EC: TAS); GO_0008283 (EC: IEA); GO_0008285 (EC: IDA, PMID: 9765203); GO_0008286 (EC: TAS); GO_0008543 (EC: TAS); GO_0010628 (EC: IMP, PMID: 15155804); GO_0017016 (EC: IEA); GO_0030216 (EC: IEA); GO_0030335 (EC: IEA); GO_0031435 (EC: IEA); GO_0032320 (EC: IEA); GO_0032402 (EC: IEA); GO_0032839 (EC: IEA); GO_0032872 (EC: TAS, PMID: 19565474); GO_0032968 (EC: IEA); GO_0034111 (EC: IEA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0043204 (EC: IEA); GO_0043539 (EC: IDA, PMID: 8388392); GO_0045087 (EC: TAS); GO_0045597 (EC: IEA); GO_0046579 (EC: IEA); GO_0047496 (EC: IEA); GO_0048011 (EC: TAS); GO_0048313 (EC: IEA); GO_0048471 (EC: IEA); GO_0048678 (EC: IEA); GO_0048870 (EC: IEA); GO_0051291 (EC: IEA); GO_0051384 (EC: IEA); GO_0051403 (EC: TAS); GO_0060674 (EC: IEA); GO_0060711 (EC: IEA); GO_0071902 (EC: IDA, PMID: 8388392); GO_0090170 (EC: TAS, PMID: 19565474); GO_0090398 (EC: IMP, PMID: 9765203); GO_2000641 (EC: TAS, PMID: 19565474) PMID: 1281467; 7601337; 7624324; 7731720; 7957875; 7969158; 8131746; 8157000; 8226933; 8388392; 8394352; 8529659; 8621729; 8626767; 8631303; 8900182; 8939914; 9006895; 9069267; 9223324; 9311917; 9325171; 9351825; 9465908; 9553107; 9558095; 9563949; 9564043; 9621077; 9733512; 9765203; 9841871; 10395327; 10402467; 10409742; 10489373; 10509564; 10523642; 10570282; 10712923; 10716983; 10748187; 10757792; 10780709; 10799874; 10806207; 10828601; 10848576; 10912793; 10958680; 10969079; 10982368; 10997882; 11044099; 11044439; 11104681; 11134045; 11226259; 11260070; 11266467; 11278389; 11279118; 11352917; 11409852; 11520933; 11535599; 11579140; 11604401; 11684694; 11726657; 11741534; 11741894; 11823456; 11891225; 11940661; 11948406; 12032872; 12063167; 12089333; 12167619; 12370306; 12456688; 12477932; 12482669; 12522135; 12522145; 12531514; 12556561; 12594221; 12609978; 12612059; 12663662; 12682854; 12689928; 12697810; 12775419; 12788955; 12792650; 12807433; 12839928; 12917419; 12975377; 14500727; 14581471; 14656894; 14672918; 14724641; 15020233; 15021912; 15069060; 15090600; 15118098; 15155804; 15231747; 15258589; 15276183; 15284233; 15292274; 15297310; 15299019; 15302887; 15353548; 15485920; 15520859; 15538402; 15543157; 15557124; 15572374; 15615716; 15638726; 15657353; 15657590; 15665520; 15757891; 15866172; 15888452; 15979847; 16086581; 16093354; 16239230; 16291755; 16313339; 16344560; 16439621; 16454711; 16533805; 16728640; 16737746; 16810323; 16820947; 16861903; 16888650; 16957420; 17038630; 17054908; 17101779; 17182854; 17192257; 17197157; 17260965; 17366577; 17419998; 17461449; 17490600; 17603482; 17623298; 17667937; 17704260; 17951252; 17979178; 17981815; 18029348; 18042262; 18060073; 18192500; 18329369; 18332145; 18390968; 18413255; 18424438; 18434598; 18533112; 18556463; 18569454; 18593598; 18617556; 18632602; 18660489; 19001375; 19014680; 19056740; 19133693; 19153083; 19156172; 19164283; 19206169; 19261809; 19322201; 19342664; 19411838; 19447520; 19453261; 19500021; 19565474; 19567590; 19625741; 19681119; 19802003; 19816936; 19835659; 19858308; 19953087; 20007706; 20019835; 20056645; 20172001; 20179161; 20212043; 20299489; 20301303; 20301365; 20302979; 20354455; 20404718; 20433920; 20512084; 20610816; 20676060; 20885957; 20926789; 20936779; 20956560; 21131601; 21139048; 21179471; 21336309; 21383288; 21447798; 21458501; 21567396; 21621846; 21675959; 21705440; 21707777; 21713404; 21835307; 21890473; 21906983; 21965271; 22037177; 22052387; 22053931; 22180573; 22188669; 22197931; 22241220; 22298595; 22327936; 22357202; 22495818; 22546605; 22588879; 22707717; 22752157; 22773810; 22791812; 22805291; 22805292; 22833572; 22902540; 22935974; 22946047; 22946697; 23000965; 23001481; 23157514; 23225884; 23237773; 23241949; 23360980; 23383273; 23524336; 23684925; 23698055; 23727904; 23746211; 23852369; 23923067; 24011934; 24091658; 24211253; 24241536; 24255178 mitogen-activated protein kinase kinase 1 HGNC:6840 HPRD:01469 MIM:176872 MAP2K1 Bin Zhao, Yue Liu, Oliver He MAPKK3 MEK3 MKK3 PRKMK3 SAPKK-2 SAPKK2 WEB: http://www.ncbi.nlm.nih.gov/gene MAP2K3 mitogen-activated protein kinase kinase 3 5606 17q11.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000187 (EC: TAS); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004702 (EC: IBA); GO_0004708 (EC: IBA); GO_0004713 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11980910); GO_0005524 (EC: IEA); GO_0005654 (EC: TAS); GO_0005737 (EC: IBA); GO_0005829 (EC: TAS); GO_0006954 (EC: IEA); GO_0007165 (EC: TAS, PMID: 7839144); GO_0019901 (EC: IPI, PMID: 11279118); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042035 (EC: IEA); GO_0045087 (EC: TAS); GO_0045860 (EC: IDA, PMID: 11980910); GO_0045893 (EC: IDA, PMID: 11980910); GO_0051403 (EC: TAS); GO_0060048 (EC: IEA) PMID: 7750576; 7839144; 8125298; 8226933; 8622669; 8626699; 8900184; 9038352; 9162092; 9465908; 9768359; 9786855; 9841871; 10497253; 10856288; 10997882; 11062067; 11062068; 11181995; 11279118; 11279172; 11414763; 11562357; 11971971; 11980910; 12024021; 12054652; 12377770; 12477932; 12589052; 12761180; 13679851; 14702039; 15276183; 15375157; 15489334; 15516490; 15677464; 15778394; 15797859; 15866172; 16341674; 16344560; 16709574; 16709866; 16728640; 17255949; 17406030; 17438131; 19047046; 19302196; 19672773; 19737936; 20067578; 20173330; 20213747; 20805296; 21044950; 21048031; 21137025; 21139048; 21206905; 21368234; 21832049; 21890473; 21900206; 21906983; 21963094; 21988832; 22154358; 22164285; 22505724; 22623531; 22696064; 23000965; 23455922; 23602568 mitogen-activated protein kinase kinase 3 Ensembl:ENSG00000034152 HGNC:6843 HPRD:03816 MIM:602315 Vega:OTTHUMG00000134322 MAP2K3 Bin Zhao, Yue Liu, Oliver He MAPKK6 MEK6 MKK6 PRKMK6 SAPKK-3 SAPKK3 WEB: http://www.ncbi.nlm.nih.gov/gene MAP2K6 mitogen-activated protein kinase kinase 6 5608 17q24.3 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000187 (EC: TAS); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0002931 (EC: IEA); GO_0004702 (EC: IBA); GO_0004708 (EC: IBA); GO_0004713 (EC: IEA); GO_0005515 (EC: IPI, PMID: 15229216); GO_0005524 (EC: IEA); GO_0005654 (EC: TAS); GO_0005737 (EC: IBA); GO_0005829 (EC: TAS); GO_0005856 (EC: IEA); GO_0006351 (EC: IEA); GO_0006355 (EC: IEA); GO_0006915 (EC: IEA); GO_0006975 (EC: TAS, PMID: 10848581); GO_0007050 (EC: TAS, PMID: 10848581); GO_0007165 (EC: TAS, PMID: 8621675); GO_0019901 (EC: IPI, PMID: 11279118); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0035872 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042493 (EC: IEA); GO_0042692 (EC: TAS); GO_0043065 (EC: IEA); GO_0045087 (EC: TAS); GO_0051149 (EC: TAS); GO_0051403 (EC: TAS); GO_0060048 (EC: IEA); GO_0070423 (EC: TAS); GO_0072709 (EC: IEA) PMID: 7750576; 8125298; 8621675; 8622669; 8626699; 8663074; 8861944; 9218798; 9430721; 9768359; 9808624; 9841871; 10094049; 10497253; 10570156; 10702308; 10838074; 10848581; 10961885; 11062067; 11062068; 11104681; 11279118; 11460167; 11562357; 11689443; 11727828; 11836244; 11971971; 12054652; 12242293; 12477932; 12509443; 12556533; 12589052; 12609980; 12697810; 12761180; 12820963; 14633987; 15229216; 15276183; 15375157; 15489334; 15492008; 15516490; 15550393; 15590691; 15677464; 15717329; 15722372; 15764709; 15778394; 15790570; 15866172; 15923648; 16157600; 16313339; 16342939; 16344560; 16498455; 16728640; 16893890; 16960152; 17079228; 17255097; 17255949; 17363905; 17363973; 17384642; 18327563; 19047046; 19141286; 19234473; 19302196; 19672773; 19675569; 19737936; 19846005; 19913121; 20067578; 20162623; 20213747; 20364819; 20628086; 20706999; 20805296; 20869211; 20932476; 21078955; 21139048; 21308746; 21368234; 21890473; 21926646; 22154358; 22164285; 22383536; 22569225; 23606331; 23744074 mitogen-activated protein kinase kinase 6 HGNC:6846 HPRD:03155 MIM:601254 MAP2K6 Bin Zhao, Yue Liu, Oliver He Jnkk2 MAPKK7 MKK7 PRKMK7 SAPKK-4 SAPKK4 WEB: http://www.ncbi.nlm.nih.gov/gene MAP2K7 mitogen-activated protein kinase kinase 7 5609 19p13.3-p13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000287 (EC: IDA, PMID: 9535930); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004674 (EC: IEA); GO_0004708 (EC: IDA, PMID: 9535930); GO_0004713 (EC: IEA); GO_0005515 (EC: IPI, PMID: 15299019); GO_0005524 (EC: IEA); GO_0005634 (EC: ISS); GO_0005737 (EC: ISS); GO_0005829 (EC: TAS); GO_0006915 (EC: IEA); GO_0006950 (EC: IDA, PMID: 9535930); GO_0007165 (EC: TAS, PMID: 9535930); GO_0007254 (EC: TAS); GO_0007257 (EC: ISS); GO_0008022 (EC: IEA); GO_0008545 (EC: IEA); GO_0019901 (EC: IPI, PMID: 14697235); GO_0019903 (EC: ISS); GO_0031435 (EC: IEA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0043525 (EC: IEA); GO_0045087 (EC: TAS); GO_0051403 (EC: IDA, PMID: 9535930); GO_0051403 (EC: TAS); GO_0072709 (EC: IEA) PMID: 9207092; 9312068; 9372971; 9488659; 9535930; 9661668; 10187804; 10347227; 10490659; 10629060; 10713157; 10756100; 10969079; 11062067; 11104681; 11274363; 11318610; 11390361; 11726277; 11836244; 11891214; 11959861; 11959862; 12138158; 12189133; 12220515; 12477932; 12659851; 12821118; 13130464; 14500727; 14697235; 14743220; 14968112; 15001580; 15276183; 15299019; 15465036; 15489334; 15753034; 15866172; 16169070; 16243842; 16313339; 16442502; 16456539; 16533805; 16802349; 16840345; 17110930; 17189706; 17485467; 18222647; 18286207; 18343408; 18436711; 18713996; 19302196; 19322201; 19737936; 19910486; 20067578; 20156194; 21074392; 21139048; 21148294; 21749326; 21890473; 21906983; 21988832; 22154358; 22159816; 22267733; 22268729; 22505724; 22509080; 22623531; 22899651; 22903704; 22939624; 23341463; 24104474; 24250222 mitogen-activated protein kinase kinase 7 Ensembl:ENSG00000076984 HGNC:6847 MIM:603014 Vega:OTTHUMG00000137368 MAP2K7 Bin Zhao, Yue Liu, Oliver He ASCR AltPrP CD230 CJD GSS KURU PRIP PrP PrP27-30 PrP33-35C PrPc p27-30 WEB: http://www.ncbi.nlm.nih.gov/gene PRNP prion protein 5621 RP5-1068H6.2 20p13 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0001933 (EC: ISS); GO_0005507 (EC: IDA, PMID: 11900542); GO_0005507 (EC: TAS, PMID: 16294306); GO_0005515 (EC: IPI, PMID: 16286452); GO_0005634 (EC: IEA); GO_0005737 (EC: TAS, PMID: 16004966); GO_0005741 (EC: IDA); GO_0005783 (EC: ISS); GO_0005794 (EC: ISS); GO_0005886 (EC: ISS); GO_0006878 (EC: NAS, PMID: 16004966); GO_0006979 (EC: ISS); GO_0007050 (EC: IEA); GO_0007411 (EC: TAS); GO_0007611 (EC: IEA); GO_0008017 (EC: IDA, PMID: 16004966); GO_0008152 (EC: TAS, PMID: 3755672); GO_0015631 (EC: IDA, PMID: 16004966); GO_0016021 (EC: IEA); GO_0019898 (EC: TAS, PMID: 16004966); GO_0031225 (EC: IEA); GO_0032689 (EC: ISS); GO_0032700 (EC: ISS); GO_0032703 (EC: ISS); GO_0042802 (EC: IPI, PMID: 16286452); GO_0043008 (EC: IEA); GO_0043066 (EC: IEA); GO_0043433 (EC: ISS); GO_0045121 (EC: ISS); GO_0046007 (EC: ISS); GO_0046686 (EC: IEA); GO_0046688 (EC: IEA); GO_0050860 (EC: ISS); GO_0051087 (EC: IEA); GO_0051260 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070885 (EC: ISS) PMID: 1346338; 1347910; 1351748; 1352724; 1357663; 1363802; 1363810; 1439789; 1671440; 1672107; 1677164; 1678248; 1683708; 1736177; 2159587; 2180366; 2564168; 2567794; 2572450; 2783132; 3014653; 3755672; 7485229; 7572084; 7592679; 7630420; 7642585; 7699395; 7783876; 7902693; 7902972; 7906019; 7913755; 8105771; 8364585; 8461023; 8676499; 8797471; 8797472; 8909447; 8962161; 9266722; 9384372; 9473220; 9482303; 9786248; 9799790; 10090891; 10581485; 10618385; 10631141; 10790216; 10900000; 10954699; 10970892; 10987652; 10988071; 11032800; 11060296; 11062072; 11100730; 11120925; 11161453; 11220690; 11244488; 11278562; 11283320; 11438139; 11559357; 11571277; 11584448; 11593450; 11684342; 11704923; 11709001; 11756421; 11775001; 11780052; 11787070; 11833672; 11840201; 11882649; 11900542; 11961239; 11986958; 12034503; 12070046; 12084159; 12093732; 12161431; 12186633; 12205650; 12356762; 12356908; 12359724; 12392052; 12399017; 12459456; 12464104; 12477932; 12514748; 12543108; 12547204; 12568340; 12590162; 12601712; 12621436; 12645301; 12659837; 12679034; 12679875; 12682740; 12684540; 12690204; 12692258; 12694397; 12719777; 12778138; 12796830; 12805563; 12867116; 12917418; 12917444; 12946346; 12952977; 12970341; 14519851; 14576159; 14593432; 14610121; 14616310; 14623188; 14645231; 14668351; 14702039; 14744790; 14745079; 14761942; 14970845; 14983221; 15050367; 15123682; 15131108; 15140132; 15145944; 15146195; 15148589; 15203115; 15208260; 15215178; 15247220; 15258222; 15266305; 15277640; 15304595; 15342556; 15469448; 15488240; 15489334; 15539564; 15555583; 15557533; 15583862; 15591591; 15609351; 15639746; 15684434; 15748158; 15775715; 15837581; 15846375; 15850959; 15862295; 15946217; 15987701; 15997418; 16004966; 16009550; 16025285; 16051190; 16099550; 16099923; 16119432; 16120605; 16156720; 16159877; 16169070; 16175355; 16187142; 16192387; 16215457; 16215462; 16217673; 16263114; 16286452; 16287045; 16294306; 16298483; 16314483; 16315279; 16324095; 16342955; 16344560; 16432880; 16434486; 16443601; 16460908; 16478730; 16519692; 16533975; 16537913; 16543824; 16545382; 16547836; 16580884; 16582585; 16672189; 16674609; 16704797; 16713569; 16750169; 16764594; 16824036; 16825951; 16825956; 16831968; 16847141; 16847689; 16858508; 16889908; 16897605; 16908519; 16914329; 16921242; 16925523; 16934224; 16950206; 16987816; 17023178; 17029361; 17047093; 17092648; 17121821; 17134829; 17149767; 17156017; 17192785; 17202849; 17242357; 17260961; 17276393; 17313881; 17334659; 17385076; 17409275; 17410475; 17414209; 17449139; 17472702; 17497959; 17500595; 17519231; 17539938; 17559305; 17560545; 17570906; 17709704; 17822808; 17827389; 17873292; 17965961; 17987393; 17996224; 18006836; 18025469; 18029348; 18038270; 18051367; 18188498; 18191917; 18204788; 18217885; 18218718; 18236005; 18236081; 18247504; 18275852; 18325785; 18332630; 18347820; 18349519; 18372408; 18406463; 18413481; 18419754; 18423780; 18425766; 18436646; 18443555; 18445040; 18478114; 18482256; 18505059; 18508914; 18539633; 18549395; 18549399; 18563793; 18597782; 18619462; 18638557; 18665216; 18691383; 18706660; 18720902; 18722532; 18786636; 18810471; 18830724; 18930924; 18955686; 18959744; 18990686; 19008948; 19010951; 19030774; 19035579; 19051123; 19056496; 19056867; 19064990; 19074151; 19077115; 19081515; 19099191; 19129193; 19140013; 19156168; 19158507; 19164910; 19172188; 19196429; 19204171; 19210573; 19212444; 19218199; 19226372; 19228673; 19249347; 19278656; 19321423; 19327369; 19351416; 19363267; 19369250; 19416900; 19476383; 19477226; 19495414; 19524515; 19534429; 19542614; 19556894; 19558790; 19583442; 19587281; 19597535; 19601795; 19602567; 19606064; 19607920; 19643043; 19675240; 19690385; 19696976; 19697238; 19698114; 19709627; 19710507; 19725833; 19728151; 19734292; 19786843; 19807656; 19822779; 19882604; 19889475; 19910028; 19911184; 19917818; 19923577; 19927125; 19996123; 20004419; 20005032; 20028338; 20035629; 20036811; 20036833; 20049591; 20077484; 20105449; 20109837; 20145049; 20175205; 20195363; 20198483; 20301407; 20392961; 20413850; 20422111; 20453509; 20465257; 20473510; 20487506; 20506117; 20515742; 20515743; 20515747; 20526338; 20526696; 20529115; 20541558; 20547212; 20547859; 20552563; 20562404; 20564047; 20564346; 20573963; 20574532; 20576610; 20583301; 20583902; 20592456; 20593190; 20613639; 20625387; 20650901; 20661422; 20685658; 20694796; 20711061; 20718410; 20724601; 20799315; 20804519; 20816195; 20838930; 20861579; 20870462; 20880607; 20919751; 20923664; 20930299; 20932979; 20949975; 20964628; 20970434; 21029243; 21058033; 21062360; 21071944; 21094273; 21107135; 21107851; 21116546; 21119307; 21193246; 21209079; 21212268; 21232818; 21257747; 21265952; 21293298; 21296677; 21297264; 21298055; 21301993; 21320996; 21323366; 21338080; 21356381; 21385869; 21439722; 21445238; 21451573; 21453198; 21478263; 21478678; 21508834; 21552571; 21559407; 21593310; 21597335; 21600043; 21616973; 21631281; 21654203; 21689534; 21743439; 21763357; 21795680; 21799773; 21804240; 21827207; 21833705; 21839748; 21841253; 21857997; 21875156; 21900252; 21911696; 21920025; 21943430; 21957246; 21957261; 21980292; 21980981; 21983261; 22002245; 22028931; 22031292; 22032174; 22036844; 22046086; 22076653; 22128151; 22129783; 22137330; 22155634; 22184125; 22210626; 22252492; 22318125; 22356913; 22363722; 22384235; 22411239; 22484317; 22505365; 22511770; 22558368; 22561193; 22584955; 22615124; 22658899; 22669942; 22675855; 22676969; 22685557; 22763467; 22788868; 22791135; 22796214; 22820080; 22842913; 22860629; 22861352; 22874673; 22876179; 22895088; 22895089; 22915585; 22918447; 22930754; 22936677; 22967749; 22972305; 22978166; 22987042; 23022479; 23090399; 23115236; 23131565; 23175838; 23209282; 23225001; 23225009; 23225390; 23256626; 23276223; 23283514; 23319218; 23324596; 23386614; 23392670; 23398456; 23399523; 23405858; 23406905; 23406923; 23436635; 23449776; 23467330; 23565236; 23577068; 23614720; 23627023; 23637596; 23638794; 23764834; 23785217; 23792955; 23825952; 23843953; 23857619; 23907583; 23959875; 23967259; 23974118; 24224623; 24225951 prion protein Ensembl:ENSG00000171867 HGNC:9449 HPRD:01453 MIM:176640 Vega:OTTHUMG00000031786 PRNP Bin Zhao, Yue Liu, Oliver He LIS2 PRO1598 RL WEB: http://www.ncbi.nlm.nih.gov/gene RELN reelin 5649 7q22 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0000904 (EC: ISS); GO_0001764 (EC: ISS); GO_0004712 (EC: ISS); GO_0005578 (EC: IEA); GO_0005615 (EC: ISS); GO_0005737 (EC: ISS); GO_0007155 (EC: IEA); GO_0007411 (EC: ISS); GO_0007417 (EC: ISS); GO_0007420 (EC: ISS); GO_0007616 (EC: IEA); GO_0008236 (EC: IEA); GO_0008306 (EC: IEA); GO_0010001 (EC: ISS); GO_0010976 (EC: ISS); GO_0014068 (EC: IEA); GO_0016358 (EC: IEA); GO_0018108 (EC: ISS); GO_0021511 (EC: ISS); GO_0021517 (EC: IEA); GO_0021766 (EC: ISS); GO_0021800 (EC: ISS); GO_0030425 (EC: ISS); GO_0032008 (EC: IEA); GO_0032793 (EC: ISS); GO_0038026 (EC: ISS, PMID: 10571240); GO_0045860 (EC: ISS); GO_0046872 (EC: IEA); GO_0048265 (EC: ISS); GO_0050731 (EC: ISS, PMID: 10571240); GO_0050795 (EC: ISS); GO_0050804 (EC: ISS); GO_0051057 (EC: ISS); GO_0051968 (EC: ISS); GO_0061003 (EC: ISS); GO_0061098 (EC: ISS); GO_0070325 (EC: ISS, PMID: 10571240); GO_0070326 (EC: ISS, PMID: 10571240); GO_0090129 (EC: ISS); GO_0097114 (EC: IEA); GO_0097119 (EC: IEA); GO_0097120 (EC: IEA); GO_0097477 (EC: IEA); GO_1900273 (EC: ISS); GO_1902078 (EC: IEA); GO_2000310 (EC: ISS); GO_2000463 (EC: ISS); GO_2000969 (EC: ISS) PMID: 7715726; 9049633; 9847074; 9861036; 10328932; 10571240; 10571241; 10612399; 10973257; 11137154; 11317216; 11408330; 11520926; 11689558; 11711858; 11880184; 12082559; 12087179; 12122039; 12135781; 12143388; 12167620; 12192627; 12363196; 12363388; 12376533; 12399956; 12645087; 12670700; 12690205; 12834112; 12853948; 12899622; 12931209; 14515139; 14702039; 14702098; 15006702; 15048647; 15048648; 15464360; 15558079; 15655250; 15690491; 15718228; 15790807; 15820235; 15961543; 15965968; 16266828; 16472607; 16481437; 16510495; 16556465; 16941662; 16951405; 16979599; 17310238; 17360894; 17365098; 17366345; 17431900; 17548821; 17621165; 17684500; 17696989; 17870056; 17955477; 18282107; 18384059; 18449964; 18593473; 18597938; 18599960; 19010793; 19054571; 19058789; 19086053; 19156168; 19230858; 19401682; 19436241; 19633980; 19691043; 19713529; 19720620; 19847460; 19922905; 19936619; 19948739; 19956836; 20010491; 20025970; 20053715; 20064940; 20150511; 20379614; 20431428; 20434133; 20436377; 20442744; 20452100; 20468075; 20554015; 20554749; 20642811; 20659411; 20697953; 20727978; 20734148; 20847288; 20882487; 21145461; 21315259; 21395570; 21549172; 21603580; 21630058; 21745129; 21814183; 21844191; 21863557; 22006801; 22006802; 22023759; 22203331; 22393371; 22394407; 22419519; 22495348; 22614235; 22797278; 22933789; 23082219; 23216241; 23236151; 23274163; 23277132; 23632168; 23934736; 24170657; 24239537 reelin Ensembl:ENSG00000189056 HGNC:9957 HPRD:02742 MIM:600514 Vega:OTTHUMG00000157247 RELN Bin Zhao, Yue Liu, Oliver He AD3 FAD PS-1 PS1 S182 WEB: http://www.ncbi.nlm.nih.gov/gene PSEN1 presenilin 1 5663 14q24.3 20140408 9606 14 protein-coding Official from a nomenclature committee GO_0000045 (EC: IEA); GO_0000122 (EC: IEA); GO_0000139 (EC: IEA); GO_0000186 (EC: IEA); GO_0000776 (EC: IDA, PMID: 9298903); GO_0001568 (EC: IEA); GO_0001708 (EC: IEA); GO_0001756 (EC: IEA); GO_0001764 (EC: IEA); GO_0001921 (EC: IEA); GO_0001947 (EC: IEA); GO_0002244 (EC: IEA); GO_0002286 (EC: IEA); GO_0002573 (EC: IEA); GO_0004175 (EC: IDA, PMID: 8755489); GO_0004190 (EC: IEA); GO_0005262 (EC: IMP, PMID: 16959576); GO_0005515 (EC: IPI, PMID: 11076969); GO_0005640 (EC: IDA, PMID: 9246482); GO_0005739 (EC: IDA, PMID: 12377771); GO_0005743 (EC: IBA); GO_0005765 (EC: IBA); GO_0005783 (EC: IDA, PMID: 15274632); GO_0005789 (EC: IEA); GO_0005790 (EC: IDA, PMID: 9632714); GO_0005791 (EC: IDA, PMID: 9632714); GO_0005794 (EC: IDA, PMID: 15274632); GO_0005813 (EC: IDA, PMID: 9298903); GO_0005887 (EC: IDA, PMID: 15274632); GO_0005938 (EC: IBA); GO_0006486 (EC: IEA); GO_0006509 (EC: IDA, PMID: 15274632); GO_0006816 (EC: IBA); GO_0006839 (EC: IEA); GO_0006974 (EC: IEA); GO_0006979 (EC: IEA); GO_0007175 (EC: IEA); GO_0007219 (EC: IEA); GO_0007220 (EC: IBA); GO_0007220 (EC: TAS, PMID: 15274632); GO_0007613 (EC: IEA); GO_0008013 (EC: IPI, PMID: 11104755); GO_0009791 (EC: IEA); GO_0009986 (EC: IBA); GO_0015031 (EC: IEA); GO_0015813 (EC: IEA); GO_0015871 (EC: IEA); GO_0016020 (EC: IDA); GO_0016021 (EC: TAS, PMID: 7596406); GO_0016080 (EC: IEA); GO_0016324 (EC: IBA); GO_0016337 (EC: IMP, PMID: 11953314); GO_0016485 (EC: IDA, PMID: 15274632); GO_0021795 (EC: IEA); GO_0021870 (EC: IEA); GO_0021904 (EC: IEA); GO_0022617 (EC: TAS); GO_0030018 (EC: IBA); GO_0030165 (EC: IPI, PMID: 10551805); GO_0030198 (EC: TAS); GO_0030326 (EC: IEA); GO_0030424 (EC: IBA); GO_0030426 (EC: IBA); GO_0031410 (EC: IEA); GO_0031594 (EC: IBA); GO_0031965 (EC: IDA, PMID: 9298903); GO_0032436 (EC: IEA); GO_0032469 (EC: IDA, PMID: 17431506); GO_0032469 (EC: IGI, PMID: 16959576); GO_0034205 (EC: IEA); GO_0035253 (EC: IBA); GO_0035556 (EC: IEA); GO_0042325 (EC: IDA, PMID: 9689133); GO_0042640 (EC: IEA); GO_0042987 (EC: IBA); GO_0042987 (EC: TAS, PMID: 15274632); GO_0043025 (EC: IBA); GO_0043065 (EC: IEA); GO_0043066 (EC: IDA, PMID: 10805794); GO_0043085 (EC: IDA, PMID: 15274632); GO_0043198 (EC: IBA); GO_0043393 (EC: IEA); GO_0043406 (EC: IEA); GO_0043524 (EC: IEA); GO_0043589 (EC: IEA); GO_0045121 (EC: IBA); GO_0045296 (EC: IBA); GO_0048167 (EC: IEA); GO_0048471 (EC: IBA); GO_0048538 (EC: IEA); GO_0048666 (EC: IEA); GO_0048705 (EC: IEA); GO_0048854 (EC: IEA); GO_0050435 (EC: IBA); GO_0050673 (EC: IEA); GO_0050771 (EC: IEA); GO_0050820 (EC: IEA); GO_0050852 (EC: IEA); GO_0051402 (EC: IEA); GO_0051444 (EC: IEA); GO_0051563 (EC: IBA); GO_0051966 (EC: IEA); GO_0060075 (EC: IEA); GO_0070588 (EC: IMP, PMID: 16959576); GO_0070765 (EC: IDA, PMID: 10801983); GO_2000059 (EC: IEA); GO_2001234 (EC: IEA) PMID: 1303289; 1349467; 1411576; 7550356; 7596406; 7623584; 7651536; 8125298; 8574969; 8634711; 8634712; 8641442; 8733303; 8742474; 8755489; 8804415; 8837617; 8875251; 8878479; 8922407; 8931704; 9007311; 9013610; 9052708; 9070286; 9073509; 9144240; 9172170; 9173929; 9223106; 9223340; 9225696; 9246482; 9298817; 9298903; 9384602; 9436726; 9437013; 9443865; 9485372; 9507958; 9521418; 9521423; 9544835; 9632714; 9689133; 9712537; 9719376; 9738936; 9771752; 9831473; 9833068; 9851443; 9851450; 9852041; 9915968; 10025789; 10037471; 10069390; 10077672; 10090481; 10092585; 10200054; 10206644; 10206645; 10208579; 10208590; 10341227; 10366599; 10369872; 10401002; 10439444; 10441572; 10446169; 10447269; 10521466; 10527805; 10533070; 10545183; 10551805; 10587643; 10593990; 10631141; 10635315; 10801777; 10801983; 10805794; 10811883; 10854253; 10891589; 10899933; 10993067; 11027672; 11030797; 11076969; 11094121; 11104755; 11110974; 11129109; 11140838; 11168528; 11200686; 11226248; 11389157; 11436125; 11444983; 11504726; 11518718; 11524469; 11568920; 11710891; 11719200; 11738826; 11744687; 11755019; 11757955; 11775232; 11799129; 11827452; 11836371; 11847232; 11876645; 11891288; 11904448; 11905990; 11912199; 11920851; 11927360; 11943765; 11953314; 11973477; 11987239; 12048239; 12048259; 12050157; 12056836; 12058025; 12070348; 12111439; 12112163; 12119298; 12121968; 12147673; 12192622; 12196555; 12198112; 12207970; 12214059; 12218704; 12230303; 12297048; 12297508; 12354302; 12374741; 12377771; 12413003; 12435726; 12444985; 12460547; 12470641; 12471034; 12477932; 12484344; 12493737; 12495082; 12508121; 12522139; 12535650; 12551931; 12603837; 12609057; 12629514; 12639958; 12660785; 12668610; 12679784; 12686406; 12740439; 12742741; 12752408; 12787561; 12794186; 12805290; 12817569; 12821663; 12843241; 12846562; 12850546; 12885573; 12885769; 12901838; 12925374; 12935881; 12960155; 13678586; 14502086; 14504279; 14515347; 14550564; 14572442; 14576165; 14581682; 14590205; 14625299; 14645205; 14702039; 14717705; 14741365; 14756819; 14759258; 14769392; 14993906; 15003276; 15004326; 15037614; 15087467; 15109302; 15115757; 15119739; 15122701; 15123598; 15123653; 15147205; 15159497; 15192701; 15205973; 15209417; 15210705; 15240571; 15257293; 15272895; 15274632; 15294909; 15308304; 15322084; 15322109; 15340889; 15341515; 15345747; 15448688; 15469450; 15474363; 15476169; 15480851; 15480879; 15489334; 15534001; 15534188; 15534260; 15537629; 15549135; 15569674; 15591316; 15622541; 15629423; 15703411; 15721744; 15722417; 15732120; 15743767; 15764367; 15764596; 15776278; 15843437; 15851849; 15866047; 15908021; 15917251; 15936948; 15946688; 15951428; 15975068; 15975090; 16006137; 16014629; 16046406; 16079160; 16116115; 16126725; 16128583; 16135086; 16139258; 16234243; 16234244; 16267640; 16305624; 16306047; 16344340; 16344560; 16376112; 16388371; 16401857; 16407539; 16423463; 16511561; 16569643; 16574645; 16605258; 16620965; 16628450; 16630834; 16641999; 16735229; 16756946; 16813565; 16814287; 16815845; 16846981; 16897084; 16908988; 16916581; 16938285; 16941492; 16952411; 16959576; 17081983; 17088253; 17099291; 17108181; 17158800; 17192785; 17207965; 17210196; 17229472; 17259169; 17268504; 17268505; 17309564; 17320044; 17349981; 17360711; 17366635; 17389597; 17401156; 17405936; 17412506; 17431506; 17489097; 17502474; 17507029; 17553989; 17560791; 17573346; 17588625; 17594345; 17627113; 17630980; 17632280; 17645236; 17718701; 17719017; 17852592; 17942194; 17962197; 17968601; 17986144; 18024701; 18028191; 18090315; 18174159; 18239458; 18293935; 18299393; 18314228; 18317569; 18320103; 18350357; 18376127; 18403054; 18430735; 18437002; 18445230; 18479822; 18525293; 18579078; 18580586; 18587238; 18591429; 18637955; 18667258; 18667537; 18706205; 18762245; 18790549; 18801744; 18830724; 18842294; 18957849; 18971484; 18996842; 19001354; 19012753; 19015863; 19017784; 19036728; 19111578; 19221408; 19232479; 19260824; 19272356; 19276550; 19276551; 19292975; 19650138; 19667325; 19675248; 19682973; 19710022; 19796846; 19797784; 19833411; 19834068; 19849793; 19853643; 19885829; 19889475; 19889971; 19924286; 20008141; 20008660; 20009122; 20018629; 20034479; 20036849; 20052609; 20106965; 20158511; 20160458; 20164095; 20168091; 20219685; 20237298; 20299451; 20301340; 20301414; 20301486; 20301678; 20307581; 20379614; 20388456; 20399254; 20413895; 20418378; 20445084; 20456003; 20460383; 20481270; 20484632; 20534741; 20541250; 20594621; 20677014; 20701429; 20724034; 20806406; 20847418; 20847436; 20858963; 20858974; 20880607; 20929727; 20970889; 21033353; 21115843; 21139048; 21143716; 21144619; 21163940; 21238544; 21277951; 21296022; 21297272; 21305049; 21323574; 21422519; 21545304; 21559374; 21621296; 21656036; 21726674; 21762767; 21784978; 21852538; 21860086; 21906983; 21914807; 21919498; 21929538; 21951279; 21959359; 21988832; 22014620; 22027014; 22045484; 22045496; 22074918; 22133015; 22214483; 22230888; 22297172; 22311977; 22312439; 22393443; 22426017; 22443192; 22459153; 22461631; 22503161; 22505025; 22508690; 22529981; 22561329; 22572737; 22607268; 22622421; 22634208; 22689582; 22710270; 22753898; 22755192; 22766738; 22810102; 22879628; 22882713; 22939629; 22975585; 23000965; 23026200; 23046926; 23064434; 23096707; 23114514; 23123781; 23134660; 23137948; 23137949; 23138650; 23237322; 23244427; 23271316; 23291095; 23337342; 23371443; 23379308; 23380992; 23396974; 23415546; 23474291; 23483213; 23489366; 23575824; 23579331; 23583593; 23584198; 23585889; 23624206; 23638752; 23660953; 23674689; 23707529; 23740836; 23884042; 23904197; 23942054; 23990795; 24145027 presenilin 1 Ensembl:ENSG00000080815 HGNC:9508 HPRD:00087 MIM:104311 Vega:OTTHUMG00000141279 PSEN1 Bin Zhao, Yue Liu, Oliver He AD3L AD4 CMD1V PS2 STM2 WEB: http://www.ncbi.nlm.nih.gov/gene PSEN2 presenilin 2 5664 1q42.13 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000139 (EC: IEA); GO_0000776 (EC: IDA, PMID: 9298903); GO_0001666 (EC: IEA); GO_0001708 (EC: IEA); GO_0001756 (EC: IEA); GO_0001933 (EC: IEA); GO_0002244 (EC: IEA); GO_0002286 (EC: IEA); GO_0002573 (EC: IEA); GO_0004175 (EC: IBA); GO_0004190 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10366599); GO_0005637 (EC: IDA, PMID: 9298903); GO_0005743 (EC: IBA); GO_0005765 (EC: IBA); GO_0005783 (EC: IDA, PMID: 15274632); GO_0005789 (EC: IEA); GO_0005794 (EC: IDA, PMID: 15274632); GO_0005813 (EC: IDA, PMID: 9298903); GO_0005829 (EC: IEA); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 15274632); GO_0005938 (EC: IBA); GO_0006509 (EC: IDA, PMID: 15274632); GO_0006816 (EC: IBA); GO_0007176 (EC: IEA); GO_0007219 (EC: TAS); GO_0007220 (EC: IBA); GO_0007220 (EC: TAS, PMID: 15274632); GO_0007613 (EC: IEA); GO_0009986 (EC: IBA); GO_0015031 (EC: IEA); GO_0016324 (EC: IBA); GO_0016485 (EC: IDA, PMID: 15274632); GO_0021904 (EC: IEA); GO_0030018 (EC: IBA); GO_0030326 (EC: IEA); GO_0030424 (EC: IBA); GO_0030426 (EC: IBA); GO_0030900 (EC: IEA); GO_0031293 (EC: TAS); GO_0031333 (EC: IEA); GO_0031594 (EC: IBA); GO_0032091 (EC: IEA); GO_0032469 (EC: IEA); GO_0035253 (EC: IBA); GO_0035556 (EC: IEA); GO_0040011 (EC: IEA); GO_0042640 (EC: IEA); GO_0042987 (EC: IBA); GO_0042987 (EC: TAS, PMID: 15274632); GO_0043025 (EC: IBA); GO_0043065 (EC: TAS); GO_0043085 (EC: IDA, PMID: 15274632); GO_0043198 (EC: IBA); GO_0043234 (EC: IDA, PMID: 9632714); GO_0045121 (EC: IBA); GO_0048011 (EC: TAS); GO_0048167 (EC: IEA); GO_0048286 (EC: IEA); GO_0048471 (EC: IBA); GO_0048538 (EC: IEA); GO_0048854 (EC: IEA); GO_0050435 (EC: IBA); GO_0050820 (EC: IEA); GO_0050852 (EC: IEA); GO_0060048 (EC: IEA); GO_0097190 (EC: TAS); GO_1902042 (EC: IEA); GO_1902043 (EC: IEA) PMID: 7638621; 7638622; 7651536; 8574969; 8618867; 8661049; 8878479; 8939861; 8940094; 8972483; 9050898; 9073509; 9219695; 9223340; 9252383; 9298903; 9384602; 9437013; 9450781; 9521418; 9558331; 9632714; 9683324; 9771752; 9813158; 9852298; 9990034; 10037471; 10069390; 10078972; 10361981; 10366599; 10369872; 10446169; 10497236; 10631141; 10652302; 10677567; 10732806; 10748169; 10854253; 10922078; 10993067; 11001931; 11076969; 11278424; 11436125; 11518718; 11568920; 11719200; 11738826; 11799129; 11847232; 11876645; 11891288; 11904448; 11987239; 12048259; 12058025; 12173418; 12196555; 12198112; 12210343; 12232783; 12297508; 12403846; 12471034; 12477932; 12556443; 12605888; 12639958; 12770698; 12787561; 12817569; 12843241; 12846562; 12885769; 12925374; 14504279; 14577603; 14741365; 14769392; 15004330; 15006697; 15274632; 15474363; 15489334; 15534001; 15537629; 15591316; 15629423; 15663477; 15721744; 15755689; 15776278; 15951428; 15975068; 16014629; 16135086; 16233903; 16258850; 16344560; 16375654; 16423463; 16474849; 16620965; 16630834; 16813565; 17268504; 17268505; 17345043; 17401156; 17401676; 17412506; 17560791; 17614368; 17727891; 17903177; 17986144; 18087668; 18283638; 18293935; 18350357; 18427071; 18591429; 18667258; 18727676; 18842294; 18854154; 18996842; 19036728; 19073399; 19276543; 19382908; 19573580; 19768372; 19834068; 19889971; 19913121; 20008660; 20009122; 20164579; 20301340; 20301414; 20301486; 20333730; 20375137; 20457965; 20468060; 20594621; 20628086; 20677014; 20701429; 20850903; 21163940; 21234330; 21285369; 21409510; 21545304; 21906983; 21914807; 21959359; 21963094; 22027014; 22045484; 22074918; 22249458; 22302987; 22312439; 22503161; 22580083; 22753229; 22755192; 22872014; 23546527; 23589300; 23707529; 23884042; 24145027 presenilin 2 Ensembl:ENSG00000143801 HGNC:9509 HPRD:02860 MIM:600759 Vega:OTTHUMG00000037563 PSEN2 Bin Zhao, Yue Liu, Oliver He Rpn4 p27 WEB: http://www.ncbi.nlm.nih.gov/gene PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 5715 12q24.31-q24.32 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000082 (EC: TAS); GO_0000209 (EC: TAS); GO_0000278 (EC: TAS); GO_0002474 (EC: TAS); GO_0002479 (EC: TAS); GO_0003713 (EC: ISS, PMID: 10567574); GO_0005515 (EC: IPI, PMID: 16189514); GO_0005634 (EC: ISS, PMID: 10567574); GO_0005654 (EC: TAS); GO_0005829 (EC: TAS); GO_0005838 (EC: NAS, PMID: 9653651); GO_0006511 (EC: NAS, PMID: 9653651); GO_0006521 (EC: TAS); GO_0006915 (EC: TAS); GO_0006977 (EC: TAS); GO_0008540 (EC: IDA, Qualifier: colocalizes_with, PMID: 19490896); GO_0010467 (EC: TAS); GO_0016032 (EC: TAS); GO_0016070 (EC: TAS); GO_0016071 (EC: TAS); GO_0031145 (EC: TAS); GO_0032024 (EC: ISS, PMID: 10567574); GO_0034641 (EC: TAS); GO_0042590 (EC: TAS); GO_0042981 (EC: TAS); GO_0043066 (EC: TAS); GO_0043425 (EC: ISS, PMID: 10567574); GO_0044281 (EC: TAS); GO_0045893 (EC: ISS, PMID: 10567574); GO_0046676 (EC: ISS, PMID: 16099819); GO_0051436 (EC: TAS); GO_0051437 (EC: TAS); GO_0051439 (EC: TAS); GO_0070682 (EC: IMP, PMID: 19490896) PMID: 8811196; 8889548; 9079628; 9653651; 9811770; 9846577; 10567574; 10799514; 10893419; 11285280; 11940657; 12167863; 12419264; 12477932; 12684681; 12719574; 12750511; 12778072; 12791267; 12808465; 12808466; 12809610; 12830140; 12840737; 12859895; 12914693; 12920286; 12970355; 14527406; 14528300; 14528301; 14550573; 14557625; 14564014; 14614829; 14702039; 15029244; 15146197; 15489334; 16099819; 16189514; 16226712; 16293776; 16341674; 16712791; 17360176; 17409098; 17516568; 18504423; 18694622; 18701138; 18838534; 19041685; 19118035; 19322201; 19490896; 19657726; 19877155; 20069546; 20878082; 21139048; 21439668; 21448710; 21477582; 21496327; 21554682; 21728808; 21813292; 21837501; 21862167; 21871126; 21890473; 21906983; 21988832; 22015693; 22053931; 22134138; 22440256; 22505724; 22863883; 22934761; 22939629; 23000965; 23282078; 23503661; 23618860; 23689538; 23824909; 24026423; 24255178 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 Ensembl:ENSG00000110801 HGNC:9567 HPRD:04394 MIM:603146 Vega:OTTHUMG00000168945 PSMD9 Bin Zhao, Yue Liu, Oliver He 10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 WEB: http://www.ncbi.nlm.nih.gov/gene PTEN phosphatase and tensin homolog 5728 10q23.3 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0000079 (EC: TAS, PMID: 10918569); GO_0000287 (EC: IEA); GO_0001525 (EC: IEA); GO_0001933 (EC: IDA); GO_0002902 (EC: IEA); GO_0004438 (EC: IDA, PMID: 9811831); GO_0004721 (EC: IDA); GO_0004722 (EC: IDA, PMID: 9256433); GO_0004725 (EC: IDA, PMID: 9256433); GO_0005161 (EC: IEA); GO_0005515 (EC: IPI, PMID: 15951562); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005737 (EC: TAS, PMID: 9367992); GO_0005739 (EC: IEA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 10760291); GO_0006470 (EC: IDA, PMID: 9256433); GO_0006470 (EC: TAS, PMID: 9367992); GO_0006644 (EC: TAS); GO_0006661 (EC: TAS); GO_0006915 (EC: ISS); GO_0007092 (EC: IDA); GO_0007173 (EC: TAS); GO_0007270 (EC: ISS); GO_0007416 (EC: ISS); GO_0007417 (EC: ISS); GO_0007507 (EC: ISS); GO_0007568 (EC: IEA); GO_0007584 (EC: IEA); GO_0007611 (EC: ISS); GO_0007613 (EC: IEA); GO_0007626 (EC: ISS); GO_0008138 (EC: IEA); GO_0008283 (EC: TAS, PMID: 10918569); GO_0008284 (EC: ISS); GO_0008285 (EC: IDA, PMID: 19057511); GO_0008285 (EC: IMP, PMID: 10468583); GO_0008289 (EC: IEA); GO_0008543 (EC: TAS); GO_0009749 (EC: IEA); GO_0009898 (EC: IDA, PMID: 10940933); GO_0010043 (EC: IEA); GO_0010975 (EC: ISS); GO_0010997 (EC: IPI); GO_0014067 (EC: TAS, PMID: 18082964); GO_0016314 (EC: IDA, PMID: 9593664); GO_0016314 (EC: TAS); GO_0016477 (EC: ISS); GO_0016605 (EC: IEA); GO_0019899 (EC: IPI, PMID: 16845383); GO_0019901 (EC: IEA); GO_0021542 (EC: ISS); GO_0021955 (EC: ISS); GO_0030165 (EC: IPI, PMID: 10646847); GO_0030336 (EC: IMP, PMID: 17880912); GO_0031642 (EC: IEA); GO_0031647 (EC: IMP, PMID: 10866658); GO_0031658 (EC: IDA); GO_0032286 (EC: ISS); GO_0032355 (EC: IEA); GO_0032535 (EC: ISS); GO_0033032 (EC: IEA); GO_0033198 (EC: IEA); GO_0033555 (EC: ISS); GO_0035176 (EC: ISS); GO_0035335 (EC: IDA, PMID: 9256433); GO_0035749 (EC: ISS); GO_0038095 (EC: TAS); GO_0042493 (EC: IEA); GO_0042711 (EC: IEA); GO_0042995 (EC: IDA, PMID: 10760291); GO_0043005 (EC: ISS); GO_0043065 (EC: IEA); GO_0043066 (EC: IEA); GO_0043197 (EC: IEA); GO_0043220 (EC: ISS); GO_0043491 (EC: ISS); GO_0043542 (EC: IEA); GO_0043647 (EC: TAS); GO_0044281 (EC: TAS); GO_0045087 (EC: TAS); GO_0045211 (EC: IEA); GO_0045471 (EC: IEA); GO_0045475 (EC: ISS); GO_0045792 (EC: ISS); GO_0046621 (EC: ISS); GO_0046685 (EC: IEA); GO_0046855 (EC: IDA, PMID: 9593664); GO_0046856 (EC: IDA, PMID: 9593664); GO_0046856 (EC: IMP); GO_0048008 (EC: IEA); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0048738 (EC: IEA); GO_0048853 (EC: ISS); GO_0048854 (EC: ISS); GO_0050680 (EC: IEA); GO_0050765 (EC: IEA); GO_0050771 (EC: ISS); GO_0050821 (EC: IDA); GO_0050852 (EC: TAS); GO_0051091 (EC: IMP); GO_0051717 (EC: IDA, PMID: 9593664); GO_0051717 (EC: TAS); GO_0051800 (EC: IDA, PMID: 9811831); GO_0051800 (EC: TAS); GO_0051895 (EC: IMP, PMID: 9616126); GO_0051898 (EC: IMP, PMID: 10760291); GO_0060024 (EC: ISS); GO_0060070 (EC: IDA); GO_0060074 (EC: ISS); GO_0060134 (EC: ISS); GO_0060179 (EC: IEA); GO_0060291 (EC: IEA); GO_0060292 (EC: IEA); GO_0060736 (EC: IEA); GO_0060997 (EC: ISS); GO_0061002 (EC: ISS); GO_0090071 (EC: IEA); GO_0090344 (EC: IEA); GO_0090394 (EC: ISS); GO_0097105 (EC: ISS); GO_0097107 (EC: ISS); GO_2000060 (EC: IDA); GO_2000134 (EC: IDA); GO_2000463 (EC: ISS); GO_2000808 (EC: ISS); GO_2001235 (EC: IEA) PMID: 7728760; 8889548; 9072974; 9090379; 9140396; 9187108; 9241266; 9256433; 9259288; 9286463; 9331071; 9345101; 9354427; 9354433; 9356475; 9367992; 9393744; 9399897; 9425889; 9467011; 9593664; 9600246; 9616126; 9635567; 9697695; 9735393; 9794233; 9797362; 9811831; 9832031; 9915974; 9927060; 10051160; 10092130; 10193515; 10213484; 10234502; 10340391; 10400703; 10400993; 10468583; 10555148; 10582703; 10646847; 10706759; 10748157; 10748870; 10760291; 10807691; 10817502; 10852473; 10866302; 10866658; 10889927; 10918569; 10940933; 10955808; 10978354; 11035285; 11058880; 11121587; 11146448; 11156385; 11179477; 11190805; 11230179; 11259087; 11270682; 11303600; 11476065; 11494117; 11504770; 11689295; 11707428; 11729185; 11748304; 11751500; 11784722; 11799112; 11801303; 11836379; 11849740; 11854177; 11857088; 11866895; 11870516; 11875759; 11896207; 11906179; 11908870; 11916965; 11925138; 11932928; 11943731; 11948419; 11948491; 11953696; 11986403; 12055674; 12067477; 12077252; 12077256; 12084351; 12085208; 12091320; 12115563; 12119278; 12133897; 12168088; 12168116; 12176037; 12177006; 12190124; 12203362; 12203792; 12209607; 12235113; 12297295; 12351634; 12367630; 12370746; 12370766; 12379854; 12414663; 12415190; 12429629; 12452054; 12459646; 12471211; 12477932; 12495846; 12508347; 12509854; 12517803; 12535639; 12543774; 12569555; 12569572; 12569575; 12620407; 12620973; 12632503; 12668978; 12684422; 12687015; 12695913; 12712134; 12717346; 12743124; 12743604; 12767263; 12788938; 12804776; 12808147; 12833416; 12839924; 12844284; 12857747; 12869565; 12917336; 12918097; 12960424; 14516315; 14519639; 14532122; 14534684; 14557489; 14559824; 14561749; 14566704; 14574156; 14623110; 14623898; 14642363; 14663583; 14674989; 14699494; 14702039; 14711368; 14724591; 14737113; 14976311; 14981940; 15009714; 15043466; 15046604; 15046605; 15069540; 15126336; 15129904; 15172121; 15196854; 15205473; 15209376; 15231710; 15240129; 15273733; 15287024; 15355975; 15382065; 15453811; 15457582; 15468057; 15475931; 15476185; 15489334; 15492994; 15500293; 15516982; 15517593; 15523694; 15532706; 15537704; 15543611; 15551732; 15564381; 15569824; 15584861; 15589575; 15623531; 15633233; 15668893; 15674339; 15701646; 15707982; 15710331; 15717329; 15725467; 15725474; 15764699; 15766664; 15784509; 15793569; 15802268; 15803130; 15805158; 15824172; 15843377; 15848175; 15891996; 15897909; 15900596; 15948123; 15951562; 15968641; 15986432; 15987703; 15988030; 15994292; 16012720; 16020969; 16052674; 16055704; 16088943; 16096376; 16107342; 16124450; 16154532; 16169070; 16179636; 16194892; 16219695; 16220831; 16274701; 16325763; 16331670; 16331889; 16371363; 16371366; 16385451; 16418168; 16421604; 16424003; 16425372; 16432235; 16436456; 16456542; 16457151; 16487009; 16496415; 16506206; 16525657; 16534839; 16537447; 16571650; 16574322; 16598737; 16621980; 16637073; 16652388; 16676006; 16676097; 16697957; 16697958; 16702386; 16704528; 16707597; 16739377; 16773562; 16793127; 16807353; 16810057; 16818626; 16821090; 16829519; 16842970; 16845383; 16849370; 16861931; 16872708; 16883792; 16912159; 16916644; 16938570; 16949921; 16951148; 16963781; 16972255; 16984224; 17000554; 17006756; 17013611; 17033968; 17043057; 17060456; 17062663; 17067457; 17097286; 17101085; 17108713; 17126809; 17151929; 17157319; 17178862; 17218260; 17218261; 17218262; 17219201; 17235455; 17236582; 17255257; 17274640; 17277022; 17300726; 17328268; 17334236; 17341483; 17345711; 17347137; 17348444; 17357516; 17369847; 17372210; 17390041; 17392703; 17393112; 17405772; 17420249; 17427195; 17438373; 17441421; 17444818; 17452061; 17452630; 17471559; 17479230; 17483060; 17490733; 17504383; 17504928; 17526801; 17563403; 17565999; 17575221; 17581634; 17593340; 17606718; 17611573; 17616684; 17636424; 17638861; 17638924; 17646270; 17657213; 17657248; 17669465; 17672936; 17681183; 17681738; 17684018; 17684142; 17699782; 17700571; 17701929; 17706140; 17711623; 17713092; 17727244; 17729405; 17761400; 17786367; 17826033; 17826953; 17827710; 17845801; 17847000; 17873065; 17873119; 17873882; 17875968; 17880912; 17886097; 17895757; 17908983; 17911267; 17912443; 17919877; 17924977; 17927875; 17927889; 17928923; 17936563; 17939398; 17940504; 17949781; 17954274; 17958724; 17959258; 17974977; 17982625; 17991315; 18006852; 18059158; 18064632; 18065496; 18066063; 18072631; 18082964; 18091387; 18174230; 18178612; 18184409; 18199536; 18199538; 18216329; 18220422; 18226337; 18226854; 18231751; 18239055; 18240926; 18240930; 18260377; 18271247; 18307411; 18316341; 18324520; 18332865; 18335551; 18335752; 18339852; 18339899; 18363844; 18377423; 18383208; 18391023; 18424911; 18425369; 18431376; 18431742; 18456716; 18460397; 18474617; 18482992; 18497947; 18498243; 18500270; 18510548; 18519768; 18544045; 18559622; 18563337; 18579579; 18586681; 18594467; 18599181; 18609703; 18616639; 18620995; 18632658; 18632660; 18652763; 18653908; 18660489; 18662848; 18669866; 18676680; 18676830; 18678645; 18700047; 18702307; 18714395; 18716620; 18720079; 18723495; 18726116; 18728972; 18755892; 18757403; 18757404; 18759867; 18765664; 18769113; 18781191; 18781614; 18787170; 18787206; 18794875; 18794879; 18794882; 18815879; 18826385; 18830414; 18831514; 18844062; 18846217; 18854827; 18928601; 18937284; 18948956; 18950007; 18953692; 19007975; 19010541; 19016009; 19036165; 19050264; 19055754; 19057511; 19064572; 19072831; 19075230; 19079342; 19079986; 19103758; 19107233; 19114656; 19116269; 19125794; 19147772; 19158375; 19164214; 19168705; 19170196; 19173293; 19185849; 19189642; 19190120; 19206008; 19206163; 19211894; 19212625; 19212633; 19221500; 19224164; 19225041; 19234438; 19237173; 19242756; 19261747; 19261849; 19265751; 19276265; 19276385; 19276401; 19293259; 19318457; 19322201; 19336370; 19339266; 19339269; 19340001; 19345329; 19350382; 19351817; 19373662; 19379695; 19398573; 19402094; 19407556; 19407851; 19417140; 19420344; 19428048; 19435893; 19437103; 19440552; 19443396; 19443706; 19449221; 19457929; 19458356; 19460752; 19463221; 19470463; 19470765; 19471547; 19473982; 19478684; 19479935; 19482022; 19483472; 19486858; 19487573; 19492080; 19502790; 19503063; 19506903; 19508975; 19522184; 19526283; 19540498; 19560785; 19563023; 19567590; 19574087; 19589246; 19608668; 19615424; 19625176; 19635806; 19638581; 19641183; 19648120; 19657395; 19661141; 19665071; 19672202; 19673018; 19679016; 19681904; 19692168; 19696618; 19724853; 19729658; 19730150; 19730774; 19733443; 19740742; 19744772; 19763916; 19764563; 19764572; 19781346; 19781347; 19784964; 19787268; 19789190; 19795445; 19798057; 19808686; 19829307; 19843859; 19846776; 19853286; 19861688; 19864456; 19881543; 19884556; 19884659; 19885556; 19903340; 19911253; 19913121; 19915616; 19922411; 19930417; 19932734; 19940030; 19953097; 19962668; 20004652; 20018398; 20029030; 20032390; 20056007; 20067111; 20079181; 20079187; 20079711; 20087603; 20102402; 20103602; 20104229; 20113523; 20154081; 20169661; 20173664; 20175786; 20177066; 20186503; 20193662; 20198299; 20198337; 20208477; 20211060; 20211065; 20212113; 20226014; 20231295; 20237279; 20237868; 20300775; 20301661; 20305378; 20309867; 20338046; 20349131; 20358487; 20371743; 20372838; 20381115; 20388916; 20389136; 20393024; 20395445; 20400965; 20407443; 20407866; 20419107; 20430845; 20436671; 20444542; 20447721; 20453000; 20458142; 20465090; 20467490; 20472848; 20505137; 20506484; 20514448; 20515662; 20523723; 20529558; 20533527; 20534535; 20546613; 20565722; 20576813; 20580873; 20590547; 20600018; 20605778; 20608352; 20622004; 20622047; 20628086; 20628624; 20631067; 20634891; 20637195; 20646419; 20664988; 20673489; 20677014; 20705603; 20711233; 20712882; 20718038; 20718712; 20736378; 20736773; 20797623; 20813662; 20813970; 20818428; 20819705; 20822910; 20845481; 20854947; 20862322; 20862607; 20864106; 20878123; 20881644; 20889565; 20926450; 20929508; 20940307; 20954279; 20955384; 20956547; 20959484; 20975834; 21029699; 21040738; 21042725; 21042775; 21042784; 21045203; 21072054; 21076047; 21084621; 21093899; 21103049; 21104017; 21110069; 21114918; 21116717; 21118966; 21129241; 21138334; 21146147; 21148296; 21151099; 21155011; 21162897; 21170675; 21177507; 21178509; 21181309; 21187093; 21194879; 21203412; 21206972; 21225506; 21228352; 21234828; 21241890; 21252315; 21289308; 21290340; 21291452; 21297666; 21303970; 21313761; 21317224; 21333374; 21343951; 21354147; 21358673; 21371429; 21404710; 21407808; 21412012; 21417916; 21421471; 21423810; 21426932; 21454687; 21456062; 21465511; 21467840; 21468554; 21473780; 21486223; 21489309; 21490305; 21518490; 21521253; 21527520; 21529704; 21531001; 21532586; 21532617; 21536651; 21556061; 21559530; 21575512; 21575859; 21602918; 21613227; 21620777; 21623071; 21627959; 21633361; 21637289; 21642958; 21646525; 21654839; 21659347; 21664656; 21685691; 21688200; 21696297; 21698421; 21719208; 21725359; 21763505; 21771908; 21804599; 21819957; 21820606; 21824802; 21828076; 21840483; 21846942; 21860425; 21873427; 21874010; 21881486; 21890624; 21901275; 21921783; 21930937; 21943825; 21948699; 21952626; 21956414; 21960672; 21984976; 21986318; 21989717; 21990315; 22000013; 22019339; 22019626; 22020193; 22021428; 22033727; 22036936; 22037217; 22045666; 22052239; 22072715; 22075159; 22076652; 22080063; 22086610; 22095074; 22095222; 22102068; 22103913; 22105477; 22110200; 22127531; 22149168; 22162762; 22166214; 22171747; 22172323; 22184110; 22185283; 22209682; 22209699; 22213145; 22213801; 22240798; 22248055; 22252256; 22262409; 22266152; 22267008; 22279049; 22281088; 22281794; 22285706; 22290228; 22299584; 22301279; 22301622; 22301702; 22320969; 22320991; 22327138; 22333553; 22336203; 22336889; 22341591; 22347425; 22350410; 22374676; 22375056; 22389271; 22394497; 22413021; 22416141; 22422068; 22427670; 22429330; 22434720; 22460813; 22465665; 22473468; 22477202; 22479427; 22486434; 22493444; 22498935; 22505997; 22520842; 22521126; 22552802; 22556379; 22563025; 22567126; 22586484; 22595938; 22613768; 22614013; 22628410; 22635024; 22639407; 22641346; 22664040; 22672595; 22674438; 22678116; 22679820; 22682934; 22684219; 22685558; 22689060; 22690848; 22700876; 22700976; 22705054; 22713753; 22727345; 22744290; 22753230; 22766795; 22770403; 22781804; 22810004; 22815832; 22820083; 22872167; 22879939; 22885155; 22892847; 22902055; 22907762; 22912864; 22937575; 22938441; 22939387; 22944341; 22955108; 22956424; 22956625; 22970944; 22982652; 22990545; 22995297; 22999923; 23013295; 23013792; 23015639; 23018874; 23030486; 23039341; 23060044; 23062208; 23064324; 23066114; 23068025; 23068099; 23082988; 23085752; 23086302; 23104175; 23110505; 23117110; 23117887; 23118026; 23119114; 23124040; 23125220; 23129115; 23133538; 23135913; 23139750; 23150879; 23151319; 23158210; 23161105; 23167185; 23171135; 23174819; 23178856; 23180960; 23183427; 23186335; 23189187; 23206599; 23219661; 23219716; 23222491; 23223894; 23242174; 23242608; 23249714; 23260327; 23274758; 23275086; 23291982; 23310986; 23314408; 23319441; 23321166; 23345234; 23348902; 23349303; 23361940; 23361946; 23375407; 23382303; 23391506; 23399955; 23402578; 23416162; 23419514; 23421960; 23426367; 23428429; 23434594; 23435381; 23465274; 23475934; 23477121; 23514585; 23533567; 23545904; 23546450; 23546539; 23546593; 23574264; 23574721; 23589550; 23591626; 23595342; 23599148; 23603434; 23604351; 23612073; 23613387; 23613406; 23613428; 23617834; 23623571; 23633456; 23633918; 23636253; 23639623; 23653096; 23660947; 23670029; 23684551; 23686804; 23690972; 23695019; 23715078; 23715080; 23715723; 23728071; 23732914; 23744781; 23764071; 23788249; 23788636; 23796801; 23796964; 23813545; 23817021; 23819399; 23832602; 23836899; 23840064; 23848554; 23851329; 23856247; 23867821; 23888040; 23902739; 23908595; 23936141; 23963458; 23992303; 24012959; 24024966; 24026406; 24062018; 24063548; 24076665; 24099768; 24113181; 24140063; 24166518; 24168499; 24221338; 24270891; 24317448; 24323028; 24367090 phosphatase and tensin homolog HGNC:9588 HPRD:03431 MIM:601728 PTEN Bin Zhao, Yue Liu, Oliver He COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 WEB: http://www.ncbi.nlm.nih.gov/gene PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5743 1q25.2-q25.3 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001516 (EC: ISS); GO_0001516 (EC: NAS); GO_0001525 (EC: IEA); GO_0004601 (EC: NAS, PMID: 14511332); GO_0004666 (EC: IDA, PMID: 1380156); GO_0005634 (EC: ISS); GO_0005737 (EC: IDA, PMID: 14511332); GO_0005737 (EC: ISS); GO_0005789 (EC: TAS); GO_0006693 (EC: TAS, PMID: 9630216); GO_0006928 (EC: TAS, PMID: 9630216); GO_0006954 (EC: IEA); GO_0006979 (EC: IEA); GO_0007566 (EC: IEA); GO_0007612 (EC: IEA); GO_0007613 (EC: IEA); GO_0008217 (EC: ISS); GO_0008285 (EC: IEA); GO_0008289 (EC: IEA); GO_0009750 (EC: IEA); GO_0010042 (EC: IEA); GO_0010226 (EC: IEA); GO_0010575 (EC: ISS, PMID: 9630216); GO_0019233 (EC: IEA); GO_0019369 (EC: TAS); GO_0019371 (EC: IDA, PMID: 1380156); GO_0019371 (EC: TAS); GO_0019372 (EC: TAS); GO_0019899 (EC: IPI, PMID: 16373578); GO_0020037 (EC: ISS); GO_0030282 (EC: IEA); GO_0030728 (EC: IEA); GO_0031394 (EC: NAS); GO_0031622 (EC: ISS); GO_0031915 (EC: IEA); GO_0032227 (EC: IEA); GO_0032355 (EC: IEA); GO_0032496 (EC: IEA); GO_0033280 (EC: IEA); GO_0034612 (EC: IEA); GO_0034644 (EC: IEA); GO_0035633 (EC: IEA); GO_0042346 (EC: IEA); GO_0042493 (EC: IEA); GO_0042640 (EC: IEA); GO_0042803 (EC: IEA); GO_0043005 (EC: IDA, PMID: 12355421); GO_0043065 (EC: IEA); GO_0043234 (EC: IEA); GO_0044281 (EC: TAS); GO_0045429 (EC: ISS, PMID: 9630216); GO_0045786 (EC: IEA); GO_0045907 (EC: IEA); GO_0045986 (EC: IEA); GO_0045987 (EC: IEA); GO_0046697 (EC: IEA); GO_0046872 (EC: IEA); GO_0048661 (EC: IEA); GO_0050473 (EC: TAS); GO_0050727 (EC: NAS, PMID: 14511332); GO_0050873 (EC: IEA); GO_0051384 (EC: IEA); GO_0051926 (EC: IEA); GO_0051968 (EC: IEA); GO_0070542 (EC: IEA); GO_0071260 (EC: IEA); GO_0071318 (EC: IEA); GO_0071456 (EC: IEP); GO_0071636 (EC: ISS, PMID: 9630216); GO_0090050 (EC: ISS, PMID: 9630216); GO_0090271 (EC: ISS, PMID: 9630216); GO_0090336 (EC: ISS); GO_0090362 (EC: ISS) PMID: 1380156; 1536575; 4514999; 7510883; 7521167; 7945196; 7947975; 8074655; 8181472; 8473346; 8581564; 8643612; 8889548; 9140046; 9520467; 9545330; 9630216; 9639560; 9661070; 10075740; 10487712; 10705655; 10811226; 10813584; 10842192; 10999846; 10999850; 11309440; 11401839; 11432874; 11687965; 11705852; 11712072; 11809691; 11809750; 11844819; 11847219; 11850206; 11867761; 11880271; 11891188; 11891209; 11894121; 11897504; 11901151; 11906292; 11911965; 11913955; 11920472; 11920515; 11939728; 11948128; 11957147; 11959891; 11972392; 11981837; 11992399; 11994539; 12006564; 12016158; 12021045; 12032335; 12050157; 12050227; 12051953; 12067908; 12070598; 12072439; 12086404; 12124799; 12131767; 12143054; 12145315; 12162677; 12164325; 12167656; 12174888; 12193665; 12195707; 12197220; 12205039; 12209724; 12209745; 12213900; 12218179; 12324457; 12349897; 12354292; 12355421; 12377741; 12378621; 12391274; 12391278; 12393863; 12393872; 12397176; 12401798; 12405290; 12433707; 12444028; 12450219; 12452062; 12459168; 12462194; 12470703; 12477932; 12480928; 12485854; 12485915; 12488433; 12493747; 12498388; 12505789; 12519124; 12519748; 12532440; 12532441; 12533667; 12555215; 12578839; 12579269; 12591723; 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22627629; 22685558; 22686557; 22696230; 22698646; 22704420; 22710400; 22718198; 22729746; 22735610; 22740037; 22758658; 22761909; 22763881; 22763923; 22782583; 22805469; 22808264; 22819245; 22822059; 22824620; 22826171; 22859522; 22863264; 22884582; 22885178; 22887904; 22900350; 22901457; 22929917; 22936450; 22942274; 22944132; 22960430; 22971811; 22972377; 22982857; 22993369; 22998445; 23028744; 23029430; 23052170; 23053989; 23059845; 23095338; 23105117; 23117931; 23124652; 23126361; 23144866; 23153564; 23179791; 23209664; 23219238; 23220503; 23221733; 23226427; 23232839; 23233037; 23239446; 23240010; 23250779; 23254909; 23261444; 23275522; 23301386; 23321929; 23326583; 23357220; 23360427; 23376640; 23393346; 23398566; 23398724; 23431194; 23434145; 23435965; 23437263; 23444045; 23446663; 23449721; 23453006; 23462226; 23494177; 23495037; 23516071; 23520664; 23523690; 23527044; 23536473; 23536693; 23548966; 23564449; 23601296; 23613363; 23620771; 23625281; 23629521; 23633486; 23642086; 23645839; 23666959; 23668350; 23678036; 23680674; 23681850; 23715826; 23729401; 23734008; 23756256; 23762835; 23765972; 23771849; 23775011; 23777936; 23809761; 23847198; 23851330; 23857285; 23869759; 23873111; 23898071; 23922175; 23955344; 23973710; 23973990; 24037722; 24052986; 24064301; 24089527; 24115825; 24127267; 24184161; 24186266; 24344016; 24436266 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) Ensembl:ENSG00000073756 HGNC:9605 HPRD:02599 MIM:600262 Vega:OTTHUMG00000035473 PTGS2 Bin Zhao, Yue Liu, Oliver He PTP1B WEB: http://www.ncbi.nlm.nih.gov/gene PTPN1 protein tyrosine phosphatase, non-receptor type 1 5770 20q13.1-q13.2 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0004725 (EC: IDA, PMID: 18074158); GO_0004725 (EC: TAS); GO_0005158 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10660596); GO_0005769 (EC: IDA); GO_0005783 (EC: IDA); GO_0005789 (EC: IEA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, Qualifier: colocalizes_with); GO_0007596 (EC: TAS); GO_0008270 (EC: IDA, PMID: 18074158); GO_0008286 (EC: IEA); GO_0009966 (EC: IMP); GO_0019221 (EC: TAS); GO_0019899 (EC: IPI); GO_0019901 (EC: IPI); GO_0030100 (EC: IDA); GO_0030168 (EC: TAS); GO_0030968 (EC: IDA); GO_0030971 (EC: IPI, PMID: 18819921); GO_0031410 (EC: IEA); GO_0031532 (EC: IMP); GO_0035335 (EC: IDA); GO_0035335 (EC: IMP, PMID: 14966296); GO_0035791 (EC: IMP, PMID: 14966296); GO_0044822 (EC: IDA); GO_0046627 (EC: NAS, PMID: 11742412); GO_0046875 (EC: IPI); GO_0060333 (EC: TAS); GO_0060334 (EC: TAS); GO_0060337 (EC: TAS); GO_0060338 (EC: TAS); GO_0060397 (EC: TAS); GO_1902202 (EC: IMP, PMID: 18819921) PMID: 1739967; 2157211; 2164224; 2546149; 7510677; 7514173; 7539106; 7540771; 7544790; 7545675; 7693694; 7935344; 8128219; 8389479; 8491187; 8621392; 8647855; 8826975; 8940099; 8940134; 8999839; 9261115; 9355745; 9391040; 9407132; 9418872; 9499405; 9553104; 9566916; 9600099; 9922143; 10350489; 10480872; 10660596; 10748206; 10889023; 10940933; 11007774; 11106648; 11136729; 11163213; 11316810; 11506178; 11579209; 11694501; 11703427; 11726652; 11742412; 11756316; 11780052; 11788587; 11833006; 11836311; 12082107; 12176037; 12237455; 12354677; 12365558; 12377785; 12388170; 12414790; 12424235; 12446583; 12468645; 12477932; 12504077; 12547827; 12554649; 12573287; 12634852; 12802338; 12802339; 12857726; 12907755; 14514610; 14722096; 14966296; 14976221; 15031294; 15039022; 15097232; 15189365; 15235769; 15258570; 15489334; 15504984; 15504985; 15588985; 15592455; 15715684; 15737620; 15821101; 15866871; 15894168; 15919813; 15919835; 15998263; 16005629; 16115959; 16249458; 16289152; 16291744; 16344560; 16407290; 16505227; 16582879; 16644720; 16652382; 16677372; 16713994; 17056636; 17081112; 17081983; 17092689; 17135270; 17159996; 17185494; 17240976; 17255364; 17333110; 17339316; 17403124; 17509747; 17560463; 17634210; 17643420; 17974954; 18029348; 18074158; 18077048; 18253097; 18332219; 18387954; 18571728; 18636124; 18660489; 18716132; 18819921; 18840608; 18846048; 18854601; 18925540; 18957266; 19008309; 19167335; 19208619; 19435911; 19491387; 19578796; 19589142; 19782770; 19948975; 20000419; 20030748; 20059965; 20101100; 20118922; 20131294; 20177231; 20236928; 20388125; 20416077; 20467438; 20493809; 20504764; 20578946; 20601126; 20615878; 20627780; 20628624; 20682687; 20864346; 20871154; 20937240; 20952588; 21123182; 21139048; 21188419; 21411736; 21442314; 21487008; 21513978; 21632985; 21676396; 21707536; 21795709; 21849469; 21869483; 21906983; 21913686; 21959757; 21972092; 21988832; 22031842; 22045810; 22169477; 22282656; 22304920; 22404968; 22450318; 22474028; 22509299; 22609202; 22655028; 22698963; 22701734; 22939629; 23129613; 23176256; 23239271; 23358729; 23428800; 23439647; 23499906; 23590304; 23640882; 23661004; 23761422; 23769735; 23814025; 23814047; 24003221; 24285539 protein tyrosine phosphatase, non-receptor type 1 Ensembl:ENSG00000196396 HGNC:9642 HPRD:01477 MIM:176885 Vega:OTTHUMG00000032729 PTPN1 Bin Zhao, Yue Liu, Oliver He CD112 HVEB PRR2 PVRR2 WEB: http://www.ncbi.nlm.nih.gov/gene PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 5819 19q13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0001618 (EC: IEA); GO_0001675 (EC: IEA); GO_0002860 (EC: IMP, PMID: 12913096); GO_0002891 (EC: IMP, PMID: 16831868); GO_0005515 (EC: IPI, PMID: 19011627); GO_0005886 (EC: TAS); GO_0005911 (EC: IDA, PMID: 9845526); GO_0005915 (EC: ISS, PMID: 10225955); GO_0007010 (EC: IEA); GO_0007156 (EC: IDA, PMID: 9845526); GO_0007165 (EC: TAS, PMID: 9657005); GO_0007286 (EC: ISS); GO_0007289 (EC: IEA); GO_0009566 (EC: IEA); GO_0009986 (EC: IDA, PMID: 16831868); GO_0015026 (EC: TAS, PMID: 9657005); GO_0016021 (EC: IDA, PMID: 12913096); GO_0019064 (EC: IDA, PMID: 12915581); GO_0030382 (EC: IEA); GO_0032990 (EC: IEA); GO_0033005 (EC: IMP, PMID: 16831868); GO_0034329 (EC: TAS); GO_0034332 (EC: TAS); GO_0042271 (EC: IMP, PMID: 12913096); GO_0042802 (EC: IPI); GO_0042803 (EC: IEA); GO_0042803 (EC: IPI, PMID: 9845526); GO_0044782 (EC: IEA); GO_0045216 (EC: TAS); GO_0045954 (EC: IMP, PMID: 16304049); GO_0046814 (EC: IDA, PMID: 12915581); GO_0050776 (EC: TAS); GO_0050839 (EC: IPI, PMID: 12913096); GO_0051654 (EC: IEA); GO_0051856 (EC: IDA, PMID: 12915581); GO_0060370 (EC: IDA, PMID: 15039383) PMID: 7622062; 9657005; 9683266; 9845526; 10196354; 10225955; 10520737; 10617658; 10627537; 10729168; 10733589; 11544254; 11602758; 11984219; 12011057; 12438620; 12477932; 12913096; 12915581; 15039383; 15146197; 15465608; 15489334; 15536144; 15607800; 15811349; 16169070; 16189514; 16304049; 16313259; 16344560; 16738668; 16740910; 16831868; 17081983; 17376543; 17534374; 17696193; 18823527; 19011627; 19478445; 19815499; 19913121; 20410314; 20572854; 20617580; 20628086; 20634891; 20662561; 20672350; 20885792; 21139048; 21383766; 21900206; 21906983; 21909109; 21982860; 21988832; 22005931; 22159054; 22927415; 23192594; 23326517; 23419831; 23465821; 23565137 poliovirus receptor-related 2 (herpesvirus entry mediator B) Ensembl:ENSG00000130202 HGNC:9707 HPRD:02879 MIM:600798 Vega:OTTHUMG00000180839 PVRL2 Bin Zhao, Yue Liu, Oliver He Rac-1 TC-25 p21-Rac1 WEB: http://www.ncbi.nlm.nih.gov/gene RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 5879 MIG5 7p22 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0000139 (EC: IEA); GO_0001891 (EC: IEA); GO_0001934 (EC: IMP); GO_0002093 (EC: IEA); GO_0002551 (EC: IEA); GO_0003382 (EC: IEA); GO_0003924 (EC: TAS, PMID: 9312003); GO_0005515 (EC: IPI, PMID: 10051605); GO_0005525 (EC: IDA, PMID: 15467718); GO_0005802 (EC: IDA, PMID: 12915445); GO_0005829 (EC: ISS); GO_0005829 (EC: TAS); GO_0005886 (EC: TAS); GO_0006928 (EC: TAS, PMID: 9572733); GO_0006954 (EC: TAS, PMID: 9572733); GO_0006972 (EC: IEA); GO_0007155 (EC: TAS, PMID: 9572733); GO_0007160 (EC: NAS, PMID: 18156211); GO_0007264 (EC: IEA); GO_0007411 (EC: TAS); GO_0007596 (EC: TAS); GO_0008283 (EC: IEA); GO_0009611 (EC: TAS, PMID: 9572733); GO_0009653 (EC: TAS, PMID: 9572733); GO_0010310 (EC: TAS, PMID: 16636067); GO_0010592 (EC: IDA, PMID: 15467718); GO_0016020 (EC: ISS); GO_0016032 (EC: TAS); GO_0017137 (EC: IEA); GO_0019897 (EC: IEA); GO_0019899 (EC: IPI, PMID: 16636067); GO_0019901 (EC: IEA); GO_0021799 (EC: IEA); GO_0021831 (EC: IEA); GO_0030027 (EC: IEA); GO_0030032 (EC: IMP, PMID: 9312003); GO_0030036 (EC: IGI, PMID: 19890013); GO_0030041 (EC: TAS, PMID: 9312003); GO_0030168 (EC: TAS); GO_0030334 (EC: IMP, PMID: 19934221); GO_0030742 (EC: IEA); GO_0030838 (EC: IEA); GO_0031295 (EC: TAS); GO_0031529 (EC: IDA, PMID: 15467718); GO_0031529 (EC: TAS, PMID: 9312003); GO_0031996 (EC: IPI, PMID: 12612085); GO_0032587 (EC: IEA); GO_0032707 (EC: IDA, PMID: 16982892); GO_0034446 (EC: IEA); GO_0035025 (EC: TAS, PMID: 9312003); GO_0035556 (EC: TAS, PMID: 9572733); GO_0038095 (EC: TAS); GO_0038096 (EC: TAS); GO_0042470 (EC: IEA); GO_0043065 (EC: TAS); GO_0043552 (EC: IEA); GO_0043652 (EC: IEA); GO_0045087 (EC: TAS); GO_0045216 (EC: IEA); GO_0045453 (EC: IEA); GO_0045740 (EC: IEA); GO_0048011 (EC: TAS); GO_0048261 (EC: TAS, PMID: 9312003); GO_0048532 (EC: IEA); GO_0048813 (EC: IEA); GO_0048870 (EC: IDA, PMID: 19403692); GO_0050690 (EC: TAS); GO_0051022 (EC: ISS); GO_0051668 (EC: IMP, PMID: 16636067); GO_0060071 (EC: IEA); GO_0060263 (EC: IDA, PMID: 16636067); GO_0070062 (EC: IDA); GO_0071526 (EC: ISS); GO_0071542 (EC: IEA); GO_0090103 (EC: IEA); GO_0097178 (EC: IEA); GO_0097190 (EC: TAS) PMID: 1643658; 1903399; 2108320; 2550440; 2674130; 7493928; 7545969; 7629060; 7673236; 7738010; 7744004; 7744773; 7938008; 7957046; 8034624; 8036496; 8107774; 8491184; 8496137; 8543060; 8631991; 8643625; 8670801; 8670882; 8702968; 8756646; 8769096; 8798539; 8939933; 8990187; 8994833; 9030878; 9033596; 9079650; 9083043; 9139723; 9148763; 9190911; 9255350; 9305638; 9312003; 9417078; 9427749; 9463375; 9487125; 9490022; 9520479; 9535855; 9572733; 9582072; 9624165; 9642115; 9786927; 9799233; 9808620; 9843499; 9857026; 10051605; 10220378; 10346909; 10394361; 10486263; 10508610; 10523675; 10559471; 10597294; 10617634; 10648409; 10673424; 10706722; 10747961; 10766742; 10779525; 10802735; 10816584; 10821761; 10869570; 10871853; 10873802; 10947987; 10954424; 10958683; 11021801; 11027608; 11030651; 11035813; 11062023; 11084340; 11090627; 11101877; 11130063; 11130076; 11134022; 11135665; 11157984; 11163217; 11258927; 11260256; 11274357; 11278572; 11284700; 11287617; 11328862; 11346801; 11368848; 11416133; 11422783; 11431473; 11438723; 11457725; 11478794; 11513578; 11513579; 11590143; 11595749; 11604131; 11685227; 11756498; 11756552; 11822867; 11839748; 11884513; 11893732; 11896062; 11948427; 11950930; 11950936; 11955434; 11973651; 11998687; 12006387; 12027902; 12038964; 12054568; 12086876; 12110184; 12115629; 12117911; 12123608; 12134158; 12169092; 12181570; 12239215; 12376548; 12376551; 12377770; 12393431; 12393632; 12453877; 12454018; 12477932; 12499846; 12511425; 12524240; 12533515; 12538863; 12547822; 12574162; 12584113; 12606638; 12612085; 12650940; 12657628; 12676940; 12690205; 12714565; 12716910; 12719789; 12730235; 12761036; 12787561; 12810717; 12819203; 12853948; 12861025; 12874273; 12879077; 12883706; 12912997; 12915445; 12919680; 12944407; 12960245; 12972426; 14506233; 14514689; 14530271; 14557270; 14573547; 14576080; 14597672; 14623895; 14625275; 14641180; 14701795; 14702039; 14729058; 14736526; 14737186; 14764880; 14960575; 14976202; 15009099; 15023524; 15048733; 15051728; 15075243; 15085137; 15121898; 15123640; 15123662; 15147912; 15166228; 15170282; 15187145; 15194684; 15194790; 15226424; 15231571; 15247305; 15247908; 15265891; 15294869; 15298851; 15303276; 15304341; 15308673; 15351707; 15377999; 15467718; 15470041; 15479739; 15489334; 15494521; 15535843; 15569826; 15579468; 15597056; 15614286; 15642257; 15642356; 15647276; 15649357; 15652748; 15673687; 15723800; 15735674; 15777850; 15817154; 15850775; 15860737; 15864311; 15864742; 15901767; 15905615; 15975516; 16002993; 16027728; 16169070; 16188938; 16195235; 16195373; 16243562; 16246732; 16257181; 16280046; 16339170; 16339173; 16354686; 16390331; 16395716; 16397238; 16410245; 16436505; 16439689; 16492808; 16507994; 16526095; 16551621; 16628218; 16628223; 16636067; 16678097; 16681996; 16687395; 16707128; 16716260; 16751412; 16762923; 16772332; 16775008; 16809619; 16825658; 16861229; 16914518; 16951224; 16982419; 16982892; 17012749; 17018610; 17018616; 17027967; 17064663; 17074883; 17077296; 17081065; 17088251; 17115053; 17121847; 17122362; 17203973; 17215244; 17229424; 17233629; 17234718; 17244648; 17245428; 17275330; 17300916; 17301947; 17347137; 17353931; 17356711; 17409253; 17428306; 17478078; 17500595; 17513457; 17517067; 17521326; 17562701; 17562712; 17565754; 17568564; 17597401; 17604276; 17615554; 17622308; 17627624; 17637758; 17663742; 17686471; 17693642; 17702745; 17702746; 17719203; 17766170; 17848544; 17851761; 17868934; 17904119; 17916560; 17940286; 17941827; 17982024; 17982280; 18005680; 18006851; 18045877; 18056353; 18064650; 18070887; 18079321; 18086571; 18088600; 18093184; 18156211; 18160397; 18160398; 18165265; 18172037; 18216165; 18235104; 18249095; 18261726; 18287089; 18296444; 18310224; 18319301; 18319303; 18321527; 18325335; 18334926; 18344974; 18424721; 18433991; 18440141; 18445079; 18463417; 18480413; 18482007; 18501711; 18508927; 18596235; 18602919; 18632858; 18644982; 18646053; 18653540; 18676680; 18684957; 18716283; 18725541; 18768751; 18769720; 18792873; 18805958; 18813807; 18813837; 18826597; 18838676; 18922799; 18984162; 19047046; 19079338; 19095647; 19107873; 19132225; 19155310; 19162367; 19165496; 19170196; 19171758; 19201754; 19234490; 19270716; 19277120; 19327867; 19344766; 19356729; 19366706; 19390057; 19403692; 19404567; 19423521; 19423540; 19429708; 19429871; 19443661; 19448673; 19463088; 19469899; 19472214; 19473989; 19480078; 19487339; 19487462; 19497305; 19505917; 19506399; 19509242; 19555660; 19563775; 19584084; 19596003; 19602482; 19617897; 19625176; 19625648; 19633358; 19639179; 19640983; 19651782; 19692168; 19706598; 19709124; 19710257; 19723872; 19726546; 19738201; 19787194; 19823586; 19826000; 19843518; 19853600; 19865048; 19890013; 19895673; 19911011; 19917258; 19926792; 19934221; 19948726; 20001745; 20054824; 20056178; 20065081; 20067638; 20070306; 20082286; 20102701; 20110267; 20116244; 20131316; 20148946; 20154214; 20167866; 20179179; 20203103; 20228810; 20237902; 20308428; 20335173; 20339118; 20339539; 20372815; 20395446; 20404345; 20406964; 20407862; 20426825; 20438785; 20451655; 20460433; 20515940; 20522449; 20530480; 20530489; 20578145; 20606682; 20629539; 20639865; 20648624; 20650890; 20660631; 20696164; 20696765; 20713492; 20814828; 20837928; 20841379; 20842205; 20852826; 20881009; 20935639; 20936779; 20945370; 20961652; 20980685; 21036915; 21056892; 21071692; 21076938; 21134286; 21139048; 21172429; 21199870; 21206905; 21266580; 21281602; 21291504; 21295525; 21319273; 21321123; 21321939; 21325632; 21347385; 21357506; 21372752; 21404019; 21439300; 21451103; 21454543; 21457935; 21474670; 21474673; 21482222; 21507984; 21525435; 21603603; 21615663; 21621326; 21622527; 21624123; 21628952; 21642434; 21677313; 21684284; 21690261; 21693584; 21704033; 21706053; 21734401; 21750647; 21756249; 21757621; 21781463; 21789714; 21806545; 21816966; 21822311; 21828072; 21844371; 21853342; 21868386; 21873980; 21885850; 21890473; 21900206; 21906983; 21936715; 21943825; 21963094; 21963679; 21964561; 21980400; 21988832; 22023324; 22036506; 22049212; 22053931; 22061968; 22080864; 22092654; 22101459; 22113496; 22114142; 22117219; 22128169; 22137120; 22142809; 22151306; 22157753; 22157762; 22179719; 22213037; 22238325; 22238672; 22276187; 22307908; 22337875; 22340048; 22349509; 22384062; 22393046; 22393062; 22407364; 22421922; 22430205; 22431917; 22467858; 22467863; 22469974; 22479308; 22494620; 22583359; 22614015; 22623428; 22646320; 22677168; 22723286; 22773836; 22774404; 22781349; 22791907; 22796473; 22808202; 22842228; 22843693; 22844345; 22845716; 22848487; 22863953; 22905193; 22939629; 22945935; 22946057; 23000965; 23035050; 23071154; 23132927; 23148218; 23184663; 23185021; 23192342; 23223568; 23253699; 23264468; 23274900; 23284172; 23295182; 23296296; 23300597; 23307871; 23322732; 23334332; 23337888; 23341328; 23382236; 23423567; 23455924; 23456597; 23461363; 23478800; 23482591; 23485997; 23537630; 23559092; 23562274; 23562278; 23586025; 23591873; 23603360; 23618859; 23624644; 23640485; 23657011; 23669401; 23707487; 23718289; 23720743; 23733346; 23760915; 23803609; 23864022; 23874639; 23900529; 23906792; 23918979; 23950142; 23989259; 24016866; 24043306; 24200678; 24250222; 24374334; 24457600 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Ensembl:ENSG00000136238 HGNC:9801 HPRD:03627 MIM:602048 Vega:OTTHUMG00000023540 RAC1 Bin Zhao, Yue Liu, Oliver He CRAF NS5 Raf-1 c-Raf WEB: http://www.ncbi.nlm.nih.gov/gene RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 5894 3p25 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000165 (EC: TAS); GO_0000186 (EC: TAS); GO_0001666 (EC: IEA); GO_0004672 (EC: TAS, PMID: 8063729); GO_0004674 (EC: IDA, PMID: 19667065); GO_0004709 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10433554); GO_0005524 (EC: IEA); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA, PMID: 17724343); GO_0005737 (EC: ISS); GO_0005741 (EC: TAS, PMID: 8929532); GO_0005794 (EC: IPI, PMID: 17724343); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 17724343); GO_0005886 (EC: TAS); GO_0006468 (EC: TAS, PMID: 8063729); GO_0006915 (EC: TAS, PMID: 8929532); GO_0007165 (EC: TAS, PMID: 8063729); GO_0007173 (EC: TAS); GO_0007190 (EC: NAS, PMID: 15385642); GO_0007264 (EC: TAS); GO_0007265 (EC: TAS); GO_0007268 (EC: TAS); GO_0007411 (EC: TAS); GO_0007507 (EC: IEA); GO_0007596 (EC: TAS); GO_0008283 (EC: TAS, PMID: 8063729); GO_0008285 (EC: IDA, PMID: 9765203); GO_0008286 (EC: TAS); GO_0008543 (EC: TAS); GO_0030168 (EC: TAS); GO_0031143 (EC: IEA); GO_0031267 (EC: IPI, Qualifier: NOT, PMID: 12194967); GO_0031333 (EC: IDA, PMID: 19667065); GO_0031434 (EC: IEA); GO_0033138 (EC: IDA, PMID: 19667065); GO_0034220 (EC: TAS); GO_0035023 (EC: TAS, PMID: 16649144); GO_0038095 (EC: TAS); GO_0042060 (EC: TAS, PMID: 15943972); GO_0042802 (EC: IPI, PMID: 17979178); GO_0042981 (EC: TAS); GO_0043066 (EC: IDA, PMID: 19667065); GO_0043154 (EC: TAS); GO_0045087 (EC: TAS); GO_0045104 (EC: IEA); GO_0045595 (EC: TAS); GO_0046872 (EC: IEA); GO_0046982 (EC: IEA); GO_0048011 (EC: TAS); GO_0055085 (EC: TAS); GO_0071550 (EC: IEA); GO_1902042 (EC: IEA); GO_2000145 (EC: TAS) PMID: 1611909; 1612588; 1639773; 1846778; 2475255; 2955285; 2993863; 3003687; 3616625; 7477354; 7517401; 7523381; 7559537; 7628630; 7644510; 7730360; 7731720; 7744247; 7766599; 7782277; 7791872; 7862125; 7935795; 7939632; 7969158; 8035810; 8063729; 8084603; 8125298; 8157000; 8307946; 8321321; 8332187; 8332195; 8349614; 8349631; 8393135; 8394352; 8408024; 8530446; 8621729; 8628317; 8663231; 8692945; 8702721; 8710867; 8753867; 8756332; 8816460; 8876196; 8887682; 8889548; 8900182; 8910675; 8911690; 8929531; 8929532; 8939988; 8962087; 9001246; 9069260; 9069267; 9091312; 9099670; 9115221; 9144171; 9150145; 9153224; 9154803; 9230211; 9234708; 9261098; 9311917; 9315742; 9446616; 9488663; 9523700; 9553107; 9624170; 9632690; 9658081; 9671314; 9689060; 9710607; 9765203; 9808624; 9819434; 9823899; 9867809; 10064593; 10205168; 10329666; 10369681; 10373531; 10433554; 10454553; 10486249; 10497893; 10498616; 10523633; 10523642; 10531364; 10557073; 10576742; 10585452; 10611249; 10620507; 10712923; 10757792; 10783161; 10837247; 10848612; 10869570; 10882715; 10887173; 10922060; 10958680; 10969079; 11005817; 11044439; 11171046; 11226259; 11231577; 11306563; 11325826; 11350735; 11409918; 11427728; 11447113; 11463741; 11520933; 11585916; 11585923; 11604401; 11676916; 11697890; 11733498; 11741534; 11751906; 11756411; 11784866; 11788587; 11853019; 11948406; 11969417; 11971957; 11997508; 12010819; 12079506; 12087097; 12127063; 12194967; 12237340; 12244094; 12360521; 12374792; 12379659; 12391160; 12429936; 12477932; 12488548; 12490852; 12551923; 12620389; 12626521; 12663662; 12682854; 12691824; 12717443; 12734410; 12774123; 12843393; 12851216; 12865432; 12925535; 12954639; 12975377; 14597674; 14623285; 14654780; 14654844; 14688025; 14724584; 14724641; 15031288; 15035987; 15041731; 15067053; 15075335; 15118098; 15122343; 15150271; 15211515; 15215316; 15302887; 15314064; 15385642; 15451031; 15459208; 15470083; 15485920; 15489334; 15520859; 15591313; 15618521; 15653554; 15657590; 15662129; 15664191; 15666389; 15674327; 15688026; 15705808; 15710605; 15711535; 15752761; 15778465; 15845549; 15849194; 15854902; 15866172; 15899852; 15925322; 15935327; 15936278; 15943972; 16029117; 16041367; 16086581; 16093354; 16172610; 16239230; 16266749; 16301319; 16330544; 16332724; 16364920; 16413928; 16465392; 16504566; 16537381; 16537561; 16565089; 16569214; 16575407; 16649144; 16707572; 16803888; 16837009; 16862215; 16883571; 16909118; 16924233; 16964381; 17018604; 17064357; 17081983; 17097642; 17243098; 17277048; 17314511; 17332776; 17353931; 17397260; 17409432; 17428866; 17462920; 17572489; 17603482; 17603483; 17614099; 17635919; 17666399; 17699868; 17724343; 17889508; 17889669; 17979178; 17998336; 18006502; 18022816; 18064632; 18182859; 18241070; 18294816; 18316782; 18332145; 18356164; 18465753; 18472967; 18483265; 18556463; 18592002; 18660489; 18708364; 18715846; 18794803; 18952605; 19001375; 19011619; 19020799; 19029954; 19037990; 19047752; 19058874; 19122653; 19133693; 19197339; 19206169; 19298812; 19357705; 19363522; 19380724; 19492075; 19595761; 19608861; 19633425; 19638574; 19638615; 19667065; 19710016; 19718030; 19730683; 19737955; 19801192; 19802003; 19805522; 19812696; 19825990; 19881545; 19895838; 19913121; 19917255; 19953087; 19953625; 20039095; 20052757; 20071468; 20086174; 20159553; 20212043; 20230813; 20234004; 20301303; 20301557; 20302979; 20364151; 20372086; 20389169; 20404846; 20489206; 20543023; 20630999; 20679480; 20686565; 20688353; 20854332; 20868603; 20947508; 21048031; 21122381; 21139044; 21139048; 21207082; 21215703; 21336309; 21348951; 21419342; 21514245; 21577205; 21617351; 21808062; 21841781; 21871886; 21881167; 21892329; 21917714; 21988832; 22020327; 22081024; 22096607; 22103831; 22110214; 22131876; 22138288; 22222486; 22225925; 22262839; 22350907; 22389993; 22421411; 22447278; 22464151; 22556409; 22605333; 22678362; 22711539; 22738312; 22752602; 22826437; 22833462; 22907845; 22922483; 22926515; 22935974; 22939624; 23076151; 23087049; 23105109; 23118896; 23153539; 23157514; 23352452; 23360980; 23383273; 23455922; 23517740; 23602568; 23610963; 23737487; 23760062; 23923067; 24108181; 24167568; 24250222; 24255178 v-raf-1 murine leukemia viral oncogene homolog 1 Ensembl:ENSG00000132155 HGNC:9829 HPRD:01265 MIM:164760 Vega:OTTHUMG00000129789 RAF1 Bin Zhao, Yue Liu, Oliver He NR1B1 RAR WEB: http://www.ncbi.nlm.nih.gov/gene RARA retinoic acid receptor, alpha 5914 17q21 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000122 (EC: IEA); GO_0000790 (EC: IDA, PMID: 17363140); GO_0000900 (EC: IEA); GO_0001657 (EC: IEA); GO_0001889 (EC: IEA); GO_0001972 (EC: IDA, PMID: 2825025); GO_0003417 (EC: IEA); GO_0003700 (EC: IDA, PMID: 18922886); GO_0003707 (EC: IEA); GO_0003708 (EC: IDA, PMID: 2825025); GO_0003713 (EC: IDA); GO_0003713 (EC: IMP, PMID: 19917671); GO_0003714 (EC: IDA); GO_0005102 (EC: IDA, PMID: 19628791); GO_0005515 (EC: IPI, PMID: 16189514); GO_0005634 (EC: IDA, PMID: 18845237); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA, PMID: 19850744); GO_0006367 (EC: TAS); GO_0006468 (EC: IMP, PMID: 16456540); GO_0007165 (EC: IDA, PMID: 2825025); GO_0007281 (EC: IEA); GO_0007283 (EC: IEA); GO_0007565 (EC: IEA); GO_0008134 (EC: IPI, PMID: 17641689); GO_0008144 (EC: IEA); GO_0008270 (EC: IEA); GO_0008284 (EC: IMP); GO_0008285 (EC: IEA); GO_0009986 (EC: IC, PMID: 2825025); GO_0010467 (EC: TAS); GO_0014068 (EC: IEA); GO_0019899 (EC: IPI, PMID: 12039952); GO_0019904 (EC: IPI); GO_0030425 (EC: IEA); GO_0030520 (EC: IDA, PMID: 15831516); GO_0030850 (EC: IEA); GO_0030853 (EC: IDA, PMID: 19917671); GO_0031490 (EC: IDA, PMID: 19917671); GO_0031641 (EC: IEA); GO_0032355 (EC: IDA, PMID: 15831516); GO_0032526 (EC: IMP, PMID: 17538076); GO_0032689 (EC: IDA, PMID: 18416830); GO_0032720 (EC: IDA, PMID: 18416830); GO_0032736 (EC: IDA, PMID: 18416830); GO_0032753 (EC: IDA, PMID: 18416830); GO_0032754 (EC: IDA, PMID: 18416830); GO_0033189 (EC: IEA); GO_0034097 (EC: IEA); GO_0035014 (EC: IEA); GO_0035264 (EC: IEA); GO_0042981 (EC: IEA); GO_0043025 (EC: IEA); GO_0043277 (EC: IMP, PMID: 19628791); GO_0043422 (EC: IPI, PMID: 16417524); GO_0043565 (EC: IEA); GO_0044323 (EC: IDA, PMID: 19917671); GO_0045471 (EC: IEA); GO_0045630 (EC: IDA, PMID: 18416830); GO_0045666 (EC: IEA); GO_0045787 (EC: IMP); GO_0045892 (EC: IDA); GO_0045893 (EC: IDA, PMID: 18845237); GO_0045893 (EC: IMP, PMID: 19628791); GO_0045944 (EC: IDA, PMID: 19850744); GO_0045944 (EC: IMP); GO_0045947 (EC: IEA); GO_0046982 (EC: IDA, PMID: 19917671); GO_0048027 (EC: IEA); GO_0048167 (EC: IEA); GO_0048384 (EC: IMP, PMID: 17538076); GO_0048471 (EC: IEA); GO_0051018 (EC: IDA); GO_0051099 (EC: IMP); GO_0051897 (EC: IEA); GO_0055012 (EC: IEA); GO_0060010 (EC: IEA); GO_0060591 (EC: IEA); GO_0061037 (EC: IEA); GO_0070374 (EC: IEA); GO_0071222 (EC: IEA); GO_0071300 (EC: IDA, PMID: 19917671); GO_0071391 (EC: IDA) PMID: 1310351; 1311253; 1314167; 1347744; 1652369; 2170850; 2175878; 2218500; 2825025; 2825036; 2899875; 7566114; 7566127; 7705655; 8051161; 8244378; 8302850; 8562957; 8598193; 8603043; 8616895; 8650544; 8887632; 9005841; 9115274; 9121466; 9192892; 9238002; 9256429; 9267036; 9288109; 9346901; 9380707; 9415406; 9430642; 9445475; 9486655; 9491782; 9531570; 9582446; 9628876; 9632709; 9642262; 9653119; 9717844; 9773978; 9795230; 9920895; 10022764; 10082574; 10207062; 10336495; 10337631; 10361124; 10428834; 10454579; 10480874; 10531331; 10567404; 10610177; 10611353; 10617585; 10698945; 10760302; 10786636; 10823961; 10860982; 10866662; 10872826; 10882070; 10882117; 10938104; 11014615; 11050004; 11106752; 11158331; 11274148; 11279242; 11331609; 11353774; 11358960; 11382777; 11439184; 11574675; 11812818; 11891284; 11929748; 11971969; 11980644; 12000751; 12009305; 12039952; 12048211; 12052862; 12060771; 12080444; 12101409; 12138096; 12193472; 12213824; 12235159; 12393611; 12399530; 12403842; 12420222; 12468549; 12477932; 12482873; 12503607; 12505266; 12549917; 12612084; 12665583; 12691149; 12805378; 12810556; 12835288; 12874288; 12935927; 12935958; 12943985; 14521715; 14559998; 14581481; 14592536; 14691372; 14702039; 14705796; 14737102; 15171703; 15246741; 15249124; 15254248; 15255287; 15308690; 15336696; 15337793; 15489334; 15528208; 15601827; 15604093; 15635645; 15670742; 15674337; 15729358; 15746941; 15808511; 15809060; 15831516; 15839736; 15870697; 15941852; 16085646; 16113082; 16179254; 16189514; 16203797; 16219912; 16239915; 16289102; 16311697; 16341674; 16344560; 16368877; 16417524; 16424870; 16432238; 16449642; 16456540; 16469706; 16480812; 16504291; 16540467; 16606617; 16630218; 16712791; 16713569; 16728697; 16769902; 16778766; 16797070; 17005281; 17195188; 17244680; 17252005; 17272513; 17272867; 17363140; 17451432; 17455211; 17456381; 17468032; 17475621; 17538076; 17560333; 17595318; 17611697; 17628022; 17641689; 17656367; 17712046; 17761950; 17943164; 17960617; 17991421; 17993618; 18000064; 18024792; 18073335; 18087039; 18180299; 18212063; 18270252; 18305945; 18416830; 18636556; 18660489; 18845237; 18922886; 18978041; 18996102; 19029980; 19100514; 19106195; 19128831; 19144644; 19144697; 19173001; 19224461; 19322209; 19341714; 19345331; 19350571; 19401466; 19458357; 19465599; 19563758; 19626135; 19628791; 19732752; 19799861; 19828696; 19850744; 19855079; 19863682; 19884280; 19902255; 19913121; 19917671; 19937600; 19965660; 20080953; 20130111; 20133701; 20133705; 20155840; 20159609; 20159610; 20185965; 20190807; 20211142; 20338915; 20346360; 20354914; 20413580; 20467438; 20543827; 20544846; 20548336; 20572854; 20574048; 20628086; 20634891; 20693704; 20736163; 20804918; 20807888; 21053424; 21150871; 21187718; 21190992; 21245861; 21254357; 21255834; 21262770; 21272161; 21310922; 21364283; 21383775; 21451111; 21613260; 21736617; 21803845; 21900206; 21923909; 21934296; 21949683; 21984809; 21988832; 22022577; 22045737; 22056876; 22135230; 22181564; 22182411; 22498738; 22982005; 22982681; 23000965; 23064648; 23064710; 23102699; 23208507; 23271512; 23448850; 23474897; 23775127; 23782583; 23847194; 23868472; 23898169; 24038216; 24183235; 24264050 retinoic acid receptor, alpha HGNC:9864 HPRD:06769 MIM:180240 RARA Bin Zhao, Yue Liu, Oliver He NFKB3 p65 WEB: http://www.ncbi.nlm.nih.gov/gene RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 5970 11q13 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0001889 (EC: IEA); GO_0001942 (EC: IEA); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0003677 (EC: IDA, PMID: 15790681); GO_0003682 (EC: IDA, PMID: 19058135); GO_0003700 (EC: IDA, PMID: 12048232); GO_0003705 (EC: IDA, PMID: 3091258); GO_0005515 (EC: IPI, PMID: 10498867); GO_0005634 (EC: IDA, PMID: 15790681); GO_0005654 (EC: TAS); GO_0005667 (EC: IDA, PMID: 12048232); GO_0005737 (EC: IDA, PMID: 15790681); GO_0005829 (EC: IDA); GO_0005829 (EC: TAS); GO_0006117 (EC: IEA); GO_0006366 (EC: IDA, PMID: 3091258); GO_0006954 (EC: IDA, PMID: 12924514); GO_0006968 (EC: NAS, PMID: 8717528); GO_0007568 (EC: IEA); GO_0008134 (EC: IPI, PMID: 10849440); GO_0008284 (EC: IDA); GO_0009612 (EC: IEA); GO_0009887 (EC: IEA); GO_0010033 (EC: IDA, PMID: 10747850); GO_0010224 (EC: IDA, PMID: 15616591); GO_0014040 (EC: IEA); GO_0016032 (EC: IEA); GO_0019221 (EC: IDA, PMID: 15876188); GO_0019901 (EC: IPI, PMID: 10521409); GO_0031293 (EC: TAS); GO_0031625 (EC: IPI, PMID: 12748188); GO_0032332 (EC: IEA); GO_0032403 (EC: IEA); GO_0032481 (EC: TAS); GO_0032495 (EC: IEA); GO_0032570 (EC: IEA); GO_0032868 (EC: IEA); GO_0033590 (EC: IEA); GO_0033613 (EC: IPI, PMID: 15489227); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042177 (EC: IEA); GO_0042301 (EC: IDA, PMID: 10521409); GO_0042493 (EC: IEA); GO_0042802 (EC: IDA, PMID: 9437432); GO_0042802 (EC: IPI, PMID: 10498867); GO_0043066 (EC: IDA, PMID: 10747850); GO_0043066 (EC: TAS); GO_0043123 (EC: IEP, PMID: 12761501); GO_0043200 (EC: IEA); GO_0043278 (EC: IEA); GO_0043565 (EC: IEA); GO_0044212 (EC: IDA, PMID: 17350185); GO_0045084 (EC: IEA); GO_0045087 (EC: TAS); GO_0045892 (EC: IDA, PMID: 17350185); GO_0045893 (EC: IDA, PMID: 17350185); GO_0045944 (EC: IDA, PMID: 17350185); GO_0045944 (EC: IMP, PMID: 10660609); GO_0046627 (EC: IEA); GO_0047485 (EC: IPI, PMID: 7739562); GO_0048011 (EC: TAS); GO_0050727 (EC: ISS); GO_0050852 (EC: TAS); GO_0051059 (EC: IPI, PMID: 8441377); GO_0051092 (EC: IDA, PMID: 15790681); GO_0051092 (EC: TAS); GO_0051591 (EC: IEA); GO_0051607 (EC: NAS, PMID: 8717528); GO_0070301 (EC: IDA); GO_0070431 (EC: IDA, PMID: 12527755); GO_0070491 (EC: IPI, PMID: 10660609); GO_0070555 (EC: IGI, PMID: 15489227); GO_0071222 (EC: IEA); GO_0071347 (EC: IDA, PMID: 18073330); GO_0071356 (EC: IDA, PMID: 18073330); GO_0071532 (EC: IEA); GO_2001237 (EC: IMP) PMID: 1493333; 1505523; 1583734; 1732726; 1740106; 2001591; 2006423; 2050119; 3091258; 3140380; 7494249; 7628694; 7651415; 7659084; 7690421; 7706261; 7729429; 7739549; 7739562; 7800480; 7838536; 7859743; 7878004; 7886940; 7907305; 7933095; 8113688; 8139561; 8152812; 8188306; 8207793; 8246997; 8255759; 8281153; 8290595; 8413211; 8423996; 8428580; 8441377; 8543190; 8550813; 8615004; 8626413; 8627654; 8642313; 8649779; 8657102; 8670842; 8676466; 8709193; 8717528; 8724035; 8746784; 8798655; 8816457; 8834464; 8887627; 8887633; 8918464; 8978697; 9057089; 9096323; 9110146; 9150141; 9250404; 9252186; 9278385; 9315679; 9437432; 9468519; 9482849; 9510190; 9525916; 9548485; 9560267; 9566873; 9566883; 9570146; 9572494; 9584164; 9584180; 9659924; 9660950; 9722548; 9724652; 9730685; 9738011; 9751059; 9792375; 9806899; 9837938; 9865693; 9950430; 9990853; 10066434; 10075655; 10207088; 10225209; 10235267; 10336463; 10357819; 10384093; 10393859; 10400814; 10446807; 10480634; 10488148; 10490645; 10498867; 10521409; 10542237; 10542243; 10562553; 10580107; 10644332; 10644726; 10646849; 10660609; 10671224; 10671503; 10723127; 10747850; 10777532; 10777610; 10799874; 10839990; 10847592; 10849440; 10903762; 10928981; 10935546; 10938077; 10958685; 10995388; 11020244; 11044099; 11114727; 11160671; 11231305; 11241736; 11274168; 11278855; 11287411; 11299302; 11313474; 11385624; 11387332; 11395507; 11511100; 11522182; 11526476; 11533489; 11564889; 11567019; 11579140; 11585920; 11590148; 11591705; 11684013; 11704662; 11739381; 11813986; 11827962; 11833470; 11880271; 11922866; 11931769; 11953203; 11964305; 11967310; 11970949; 11971907; 11976329; 11980335; 11983170; 12019209; 12027803; 12040027; 12040437; 12048232; 12052823; 12055073; 12057007; 12067985; 12077347; 12080470; 12134007; 12138131; 12167619; 12173051; 12181450; 12213807; 12244126; 12350227; 12377934; 12393603; 12398897; 12403783; 12419806; 12419817; 12427593; 12429528; 12444202; 12456660; 12473373; 12477932; 12482669; 12485413; 12493764; 12504098; 12509469; 12517770; 12527755; 12540841; 12553906; 12556500; 12559944; 12581153; 12589049; 12606945; 12606947; 12618429; 12618762; 12628924; 12651903; 12665595; 12672800; 12673201; 12690099; 12693954; 12700228; 12707271; 12736262; 12748188; 12761501; 12767057; 12820969; 12829026; 12842894; 12843241; 12881425; 12917431; 12924514; 12972607; 14508515; 14557267; 14560022; 14576841; 14587029; 14593105; 14597638; 14600157; 14600158; 14623898; 14624448; 14645533; 14657027; 14685242; 14688382; 14690596; 14711835; 14716817; 14743216; 14769797; 14966904; 14970236; 15013781; 15016307; 15029197; 15073167; 15073170; 15079071; 15093710; 15125834; 15128824; 15130920; 15140884; 15152190; 15155458; 15167972; 15171256; 15184881; 15192014; 15200413; 15205244; 15226358; 15231833; 15246972; 15256061; 15276183; 15315758; 15355351; 15383283; 15465828; 15484295; 15485901; 15489227; 15494311; 15496460; 15498932; 15499023; 15543947; 15556937; 15599399; 15601829; 15616591; 15616592; 15652748; 15657065; 15657351; 15657437; 15660126; 15671037; 15682491; 15718492; 15735750; 15746428; 15775976; 15790681; 15799966; 15806143; 15845455; 15845545; 15849198; 15876188; 15885892; 15905616; 15913553; 15917220; 15935276; 15975999; 15988014; 16007092; 16009713; 16034126; 16046471; 16052512; 16081638; 16105840; 16135789; 16186799; 16204234; 16214042; 16243805; 16285952; 16291753; 16319923; 16322332; 16329838; 16331275; 16344560; 16382138; 16407283; 16408727; 16410078; 16452207; 16456540; 16477006; 16481475; 16483679; 16497702; 16497732; 16497877; 16498455; 16524505; 16573520; 16584809; 16608838; 16723503; 16728495; 16735506; 16740634; 16785565; 16829531; 16931600; 16940169; 16951195; 16966488; 16982623; 16997282; 16998237; 16998474; 17000776; 17003035; 17003112; 17012367; 17023015; 17031851; 17041012; 17054067; 17070014; 17079333; 17085785; 17136479; 17138826; 17157788; 17158457; 17167080; 17183367; 17196614; 17207971; 17242904; 17255956; 17258784; 17296604; 17301240; 17317104; 17350185; 17353187; 17362989; 17374495; 17403902; 17439942; 17452529; 17468103; 17468759; 17478731; 17493236; 17521736; 17525529; 17530443; 17537731; 17540171; 17586618; 17590503; 17611696; 17612295; 17620405; 17622249; 17626072; 17631635; 17660862; 17661632; 17675239; 17707233; 17708800; 17715045; 17720813; 17785205; 17827154; 17882263; 17889033; 17889859; 17904523; 17911169; 17932106; 17947640; 17956668; 17959673; 17962362; 17962807; 17969521; 17982102; 17986144; 18021261; 18024283; 18025803; 18034190; 18035048; 18036607; 18037904; 18040287; 18045535; 18059344; 18061975; 18073330; 18095109; 18163488; 18163503; 18172215; 18174252; 18178962; 18187620; 18188593; 18201972; 18212740; 18215193; 18215660; 18227347; 18241676; 18249093; 18280497; 18294642; 18314621; 18316612; 18362147; 18362169; 18422166; 18424071; 18424438; 18434448; 18439422; 18461473; 18466468; 18541671; 18550535; 18598236; 18600306; 18607537; 18650421; 18652316; 18660489; 18692180; 18701591; 18703796; 18714023; 18720533; 18779315; 18798274; 18800364; 18823280; 18854154; 18947494; 18952281; 18976975; 18981184; 18983609; 18990707; 18991026; 19019440; 19038492; 19043589; 19046417; 19058135; 19060926; 19064727; 19064995; 19067848; 19087517; 19103749; 19124506; 19124804; 19132086; 19135889; 19140318; 19157506; 19185596; 19197368; 19204000; 19219072; 19262565; 19270718; 19275580; 19275583; 19289499; 19296848; 19300393; 19309400; 19330832; 19339690; 19350539; 19407977; 19422389; 19428110; 19433587; 19448676; 19453840; 19458474; 19483084; 19502777; 19507243; 19520742; 19573080; 19591173; 19591457; 19619938; 19622906; 19654331; 19662361; 19664333; 19683540; 19706600; 19706715; 19706766; 19734210; 19734226; 19746155; 19751727; 19758175; 19764566; 19773279; 19779021; 19789307; 19800042; 19819989; 19860880; 19864627; 19911008; 19912635; 19913121; 19940030; 19955102; 19957349; 20001970; 20020487; 20026048; 20030038; 20032510; 20035271; 20038977; 20048074; 20049872; 20065107; 20080798; 20100341; 20118004; 20124457; 20127516; 20133937; 20139419; 20145242; 20154269; 20160011; 20164172; 20190799; 20194077; 20211864; 20233629; 20237821; 20299548; 20333651; 20346213; 20346360; 20379146; 20380454; 20385564; 20388487; 20388791; 20406971; 20410276; 20421348; 20428758; 20448286; 20457620; 20457835; 20460684; 20462637; 20482821; 20501702; 20514026; 20514451; 20519647; 20538607; 20547752; 20551178; 20562110; 20564628; 20568106; 20568250; 20571344; 20581863; 20585448; 20596086; 20596645; 20617556; 20619728; 20628086; 20639196; 20651843; 20664977; 20672329; 20674992; 20706634; 20729202; 20740673; 20797629; 20861353; 20862798; 20872175; 20936779; 20942234; 20955203; 20957413; 20980497; 21029719; 21030982; 21041296; 21042750; 21042766; 21048031; 21048223; 21056029; 21084693; 21088498; 21131967; 21139048; 21161056; 21165563; 21167650; 21169414; 21187904; 21189284; 21199955; 21211341; 21217772; 21253969; 21262351; 21268019; 21270162; 21278793; 21294676; 21300980; 21310030; 21339307; 21344388; 21364020; 21364927; 21383699; 21395185; 21430048; 21442076; 21451109; 21454528; 21515635; 21518757; 21549062; 21552325; 21576089; 21576359; 21593732; 21598303; 21610149; 21628458; 21660047; 21674474; 21688043; 21697472; 21697760; 21734268; 21742773; 21750107; 21765619; 21771706; 21771876; 21796632; 21803611; 21816815; 21881048; 21884980; 21887328; 21889270; 21900165; 21900206; 21901538; 21903422; 21903858; 21908405; 21918864; 21929290; 21968997; 21976665; 21983014; 21983900; 21988832; 21996578; 21996739; 22008847; 22020940; 22021035; 22022389; 22027781; 22028792; 22038347; 22047608; 22069318; 22081069; 22102084; 22103356; 22105366; 22108531; 22139845; 22141576; 22186294; 22187158; 22196717; 22220474; 22249179; 22261743; 22282354; 22292036; 22302993; 22312446; 22330808; 22334708; 22337883; 22341466; 22390170; 22397926; 22422610; 22480519; 22485186; 22493284; 22496479; 22525504; 22528837; 22535373; 22545750; 22552851; 22558476; 22590978; 22591684; 22592405; 22593190; 22619232; 22634383; 22649547; 22666436; 22670315; 22688014; 22708120; 22709495; 22740410; 22748181; 22763042; 22781898; 22797919; 22804476; 22809882; 22836752; 22842493; 22859938; 22863883; 22892758; 22927901; 22931618; 22948157; 22955280; 22964303; 23027940; 23038213; 23046941; 23053371; 23054188; 23056468; 23069812; 23071666; 23077289; 23083102; 23088768; 23100252; 23115242; 23123196; 23128233; 23134958; 23150684; 23164673; 23195252; 23209664; 23219896; 23238643; 23250430; 23267096; 23269273; 23281696; 23296075; 23318455; 23349803; 23354694; 23454417; 23456480; 23467542; 23482348; 23504993; 23507189; 23510472; 23528368; 23541563; 23543150; 23563313; 23576453; 23576567; 23583404; 23592772; 23603903; 23604637; 23618358; 23624912; 23636254; 23664323; 23708311; 23712703; 23715780; 23716661; 23734002; 23776612; 23797602; 23824799; 23860225; 23874387; 23904475; 23904479; 23940701; 23963448; 23994473; 24012639; 24039253; 24042437; 24067962; 24096876; 24152492; 24175631; 24248593; 24250222; 24260304; 24302727; 24321067; 24457600 v-rel avian reticuloendotheliosis viral oncogene homolog A Ensembl:ENSG00000173039 HGNC:9955 HPRD:01241 MIM:164014 Vega:OTTHUMG00000166566 RELA Bin Zhao, Yue Liu, Oliver He RHEB2 WEB: http://www.ncbi.nlm.nih.gov/gene RHEB Ras homolog enriched in brain 6009 7q36 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0003924 (EC: TAS, PMID: 8206940); GO_0005515 (EC: IPI); GO_0005525 (EC: ISS); GO_0005681 (EC: IEA); GO_0005829 (EC: TAS); GO_0005886 (EC: IEA); GO_0007050 (EC: TAS); GO_0007165 (EC: TAS, PMID: 8661031); GO_0007264 (EC: IEA); GO_0008286 (EC: TAS); GO_0016020 (EC: TAS, PMID: 8206940); GO_0019003 (EC: IEA); GO_0019901 (EC: IEA); GO_0030425 (EC: IEA); GO_0032008 (EC: IMP); GO_0043025 (EC: IEA); GO_0046872 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 8206940; 8543055; 8661031; 8889548; 9001246; 9099708; 9130713; 9847074; 10924367; 11980706; 12477932; 12690205; 12771962; 12820960; 12842888; 12853948; 12869548; 12869586; 12906785; 14702039; 15150271; 15308774; 15340059; 15388940; 15489334; 15728574; 15755954; 15772076; 15775987; 15809305; 15809346; 15854902; 15878852; 15951850; 16006564; 16098514; 16344560; 16631613; 16803888; 16915281; 17018601; 17077083; 17470430; 17928295; 17991864; 18324915; 18521078; 18550814; 18650380; 18658153; 18708577; 18708578; 18842593; 18948269; 19056867; 19222999; 19570981; 19636822; 19838215; 20048149; 20053679; 20127734; 20354165; 20368287; 20375271; 20388784; 20554106; 20685651; 20732420; 20818424; 20837708; 21048031; 21135540; 21139048; 21163940; 21336308; 21412983; 21437936; 21784859; 21890473; 21906983; 21963094; 21988832; 23409921; 23863162 Ras homolog enriched in brain Ensembl:ENSG00000106615 HGNC:10011 HPRD:03188 MIM:601293 Vega:OTTHUMG00000157330 RHEB Bin Zhao, Yue Liu, Oliver He HU-1 MAPKAPK1A RSK RSK1 WEB: http://www.ncbi.nlm.nih.gov/gene RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 6195 RP11-492M19.2 1p 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000287 (EC: IEA); GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004674 (EC: IDA, PMID: 10679322); GO_0005515 (EC: IPI); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA); GO_0005819 (EC: IEA); GO_0005829 (EC: TAS); GO_0007049 (EC: IEA); GO_0007165 (EC: TAS, PMID: 8141249); GO_0007268 (EC: TAS); GO_0007411 (EC: TAS); GO_0030307 (EC: TAS, PMID: 18813292); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0043027 (EC: IDA, PMID: 18402937); GO_0043066 (EC: IMP, PMID: 11684016); GO_0043154 (EC: IDA, PMID: 18402937); GO_0043555 (EC: TAS, PMID: 18813292); GO_0043620 (EC: TAS, PMID: 18813292); GO_0045087 (EC: TAS); GO_0045597 (EC: TAS, PMID: 18813292); GO_0045944 (EC: IMP); GO_0048011 (EC: TAS); GO_0051403 (EC: TAS); GO_2000491 (EC: IMP, PMID: 10679322) PMID: 1545823; 1545828; 8125298; 8141249; 8248197; 8413226; 8601309; 8630373; 8663493; 8688081; 8756728; 8939914; 9030586; 9214631; 9218456; 9261139; 9353277; 9381178; 9430688; 9528769; 9687510; 9721103; 9770464; 9829964; 9914500; 9915826; 10318869; 10469565; 10480933; 10521512; 10635333; 10648825; 10673502; 10679322; 10723127; 10753652; 10837486; 10880354; 10949026; 10980595; 11139588; 11160957; 11171059; 11175347; 11260258; 11297520; 11432835; 11500364; 11507039; 11551945; 11684016; 11861786; 11914378; 12019261; 12036856; 12080086; 12093745; 12213813; 12235136; 12393804; 12477932; 12569367; 12594221; 12618428; 12626518; 12832467; 12842905; 12897128; 12917345; 12917364; 14702039; 14709557; 15024086; 15073170; 15112576; 15117958; 15121878; 15206906; 15276183; 15342917; 15489334; 15615708; 15647351; 15757502; 15861136; 15905173; 15910284; 15929978; 16039586; 16213824; 16217014; 16223362; 16282323; 16341674; 16626623; 16710414; 16738324; 17081983; 17192257; 17512525; 17634259; 17965187; 18029348; 18084084; 18402937; 18450423; 18451027; 18722121; 18813292; 18950845; 19036157; 19150432; 19332537; 19470470; 19675165; 19716794; 19808666; 19913121; 20048145; 20304964; 20628086; 20849292; 21035469; 21044953; 21075852; 21139048; 21423205; 21501342; 21832046; 21890473; 21900206; 21906983; 21963094; 21987572; 22006917; 22031759; 22050627; 22246185; 22249268; 22357623; 22427657; 22505724; 22586265; 22674792; 22683790; 22863883; 22865467; 22939624; 23401857; 23455922; 24036112 ribosomal protein S6 kinase, 90kDa, polypeptide 1 Ensembl:ENSG00000117676 HGNC:10430 HPRD:03402 MIM:601684 Vega:OTTHUMG00000004003 RPS6KA1 Bin Zhao, Yue Liu, Oliver He PS6K S6K S6K-beta-1 S6K1 STK14A p70 S6KA p70(S6K)-alpha p70-S6K p70-alpha WEB: http://www.ncbi.nlm.nih.gov/gene RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 6198 17q23.1 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000082 (EC: IMP, PMID: 14673156); GO_0003009 (EC: IEA); GO_0004672 (EC: IDA, PMID: 17936702); GO_0004711 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12150926); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA, PMID: 19085255); GO_0005739 (EC: IDA, PMID: 17936702); GO_0005741 (EC: IEA); GO_0005829 (EC: TAS); GO_0006468 (EC: IDA, PMID: 19085255); GO_0006915 (EC: IEA); GO_0007165 (EC: TAS, PMID: 1922062); GO_0007281 (EC: IEA); GO_0007568 (EC: IEA); GO_0007584 (EC: IEA); GO_0007616 (EC: IEA); GO_0008286 (EC: TAS); GO_0009408 (EC: IEA); GO_0009611 (EC: IEA); GO_0009612 (EC: IEA); GO_0009636 (EC: IEA); GO_0009749 (EC: IEA); GO_0009986 (EC: IEA); GO_0014732 (EC: IEA); GO_0014878 (EC: IEA); GO_0014911 (EC: IEA); GO_0016477 (EC: IEA); GO_0030054 (EC: IEA); GO_0031929 (EC: IDA, PMID: 12150926); GO_0032496 (EC: IEA); GO_0033574 (EC: IEA); GO_0033762 (EC: IEA); GO_0034612 (EC: IEA); GO_0042277 (EC: IEA); GO_0042493 (EC: IEA); GO_0043005 (EC: IEA); GO_0043066 (EC: IMP, PMID: 17936702); GO_0043201 (EC: IEA); GO_0043491 (EC: IEA); GO_0045202 (EC: IEA); GO_0045471 (EC: IEA); GO_0045727 (EC: IMP, PMID: 18423201); GO_0045931 (EC: IMP, PMID: 14673156); GO_0045948 (EC: IMP, PMID: 16763566); GO_0046324 (EC: IEA); GO_0046627 (EC: IMP, PMID: 18952604); GO_0048015 (EC: TAS, PMID: 9445476); GO_0048471 (EC: IEA); GO_0048633 (EC: IEA); GO_0048661 (EC: IEA); GO_0051384 (EC: IEA); GO_0071363 (EC: IDA, PMID: 17936702); GO_2001237 (EC: IEA) PMID: 1922062; 8871403; 9271440; 9427642; 9445476; 9465032; 9653190; 9804755; 10089566; 10197603; 10200280; 10567431; 10601311; 10807185; 10971657; 10973943; 11013237; 11171059; 11279232; 11297520; 11331760; 11438723; 11500364; 11516946; 11733037; 11774034; 11853558; 11914378; 12014987; 12019261; 12023960; 12052877; 12054624; 12150925; 12150926; 12477932; 12529391; 12586835; 12604610; 12718876; 12733712; 12747804; 12759354; 12801526; 12869548; 14673156; 14679009; 14702039; 14709557; 15024086; 15028555; 15066126; 15071500; 15149849; 15158097; 15203190; 15236312; 15249583; 15304500; 15314020; 15319361; 15341740; 15342556; 15474452; 15533996; 15589845; 15623621; 15659381; 15692808; 15696579; 15723049; 15790787; 15809305; 15812314; 15843522; 15854902; 15896331; 15899889; 15905173; 15953364; 16049009; 16109716; 16183647; 16262259; 16286006; 16364302; 16407298; 16434552; 16469801; 16640565; 16715128; 16763566; 16810323; 16818690; 16826166; 16837165; 16839745; 16883576; 16895915; 16899564; 16914728; 16922504; 16931574; 16962100; 16964243; 17043309; 17045920; 17052453; 17053147; 17081983; 17255101; 17310252; 17336708; 17386266; 17427199; 17512525; 17569770; 17599906; 17604271; 17616691; 17622239; 17693255; 17908691; 17936702; 18025271; 18279656; 18423201; 18451027; 18461003; 18505677; 18565837; 18652687; 18660489; 18813808; 18829578; 18952604; 19065636; 19085255; 19112174; 19168580; 19240722; 19266162; 19285034; 19322201; 19553685; 19730801; 19801633; 19815051; 19864428; 19881535; 19889638; 19913121; 19914247; 19936974; 19953087; 19961954; 19995915; 20137651; 20157535; 20173664; 20187284; 20190034; 20374740; 20410302; 20423989; 20433920; 20459645; 20599538; 20599721; 20617335; 20628086; 20657550; 20731018; 20819778; 20932932; 20953835; 20961652; 21035469; 21048031; 21067588; 21071439; 21093473; 21184268; 21224254; 21228102; 21258406; 21289241; 21292829; 21297943; 21390332; 21397856; 21424608; 21440577; 21444676; 21460630; 21467264; 21536668; 21541441; 21561857; 21602892; 21609291; 21710263; 21757621; 21832049; 21833088; 21900206; 21981924; 21986499; 21988832; 22110663; 22113269; 22248270; 22286763; 22348058; 22391570; 22439934; 22442669; 22457523; 22493283; 22544753; 22574368; 22645648; 22684641; 22705322; 22795649; 22871496; 22939624; 22977662; 23044732; 23045529; 23128233; 23184942; 23251661; 23273915; 23276696; 23330000; 23376066; 23393338; 23632629; 23731517; 23739915; 23886172; 23938603; 24023352; 24030155; 24067973; 24089522; 24157791; 24247430; 24250222; 24277938 ribosomal protein S6 kinase, 70kDa, polypeptide 1 Ensembl:ENSG00000108443 HGNC:10436 HPRD:10202 MIM:608938 Vega:OTTHUMG00000150642 RPS6KB1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene RYR3 ryanodine receptor 3 6263 15q14-q15 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0005219 (EC: ISS); GO_0005219 (EC: TAS, PMID: 19095005); GO_0005509 (EC: IEA); GO_0005516 (EC: IEA); GO_0006816 (EC: IMP, PMID: 9395096); GO_0006941 (EC: IEA); GO_0015278 (EC: IMP, PMID: 9395096); GO_0016021 (EC: ISS); GO_0030314 (EC: IEA); GO_0033017 (EC: ISS); GO_0033017 (EC: TAS); GO_0034220 (EC: TAS); GO_0048471 (EC: IEA); GO_0048763 (EC: IEA); GO_0051289 (EC: ISS); GO_0051481 (EC: IEA); GO_0055085 (EC: TAS); GO_0070588 (EC: ISS); GO_0071277 (EC: ISS); GO_0071286 (EC: ISS); GO_0071313 (EC: ISS); GO_0071318 (EC: ISS) PMID: 1320290; 7523185; 7556644; 8276408; 9384575; 9395096; 9515741; 9607712; 10508160; 11171121; 11598113; 12213830; 12354756; 12471029; 12565913; 14550562; 14702039; 14970260; 17110338; 18588595; 19009018; 19095005; 19096130; 19581603; 20009918; 20195357; 20201926; 20379614; 20424473; 20962236; 21139048; 21145461; 21531043; 21810988; 21881589; 22100703; 22627881; 22664477; 22948152; 23393343; 24024966; 24026422; 24211435; 24457600 ryanodine receptor 3 RYR3 Bin Zhao, Yue Liu, Oliver He NEF S100 S100-B S100beta WEB: http://www.ncbi.nlm.nih.gov/gene S100B S100 calcium binding protein B 6285 21q22.3 20140408 9606 21 protein-coding Official from a nomenclature committee GO_0001726 (EC: IDA, PMID: 10913138); GO_0005509 (EC: NAS, PMID: 9519411); GO_0005515 (EC: IPI, PMID: 10913138); GO_0005576 (EC: TAS); GO_0005615 (EC: IEA); GO_0005634 (EC: IDA); GO_0005737 (EC: IDA, PMID: 10913138); GO_0005737 (EC: ISS); GO_0007409 (EC: TAS, PMID: 8202493); GO_0007417 (EC: TAS, PMID: 8202493); GO_0007611 (EC: ISS); GO_0007613 (EC: IEA); GO_0008270 (EC: ISS); GO_0008283 (EC: TAS, PMID: 8202493); GO_0008284 (EC: IEA); GO_0008360 (EC: IEA); GO_0042802 (EC: IPI, PMID: 10913138); GO_0042803 (EC: IDA, PMID: 10913138); GO_0042803 (EC: IPI, PMID: 9519411); GO_0043025 (EC: IEA); GO_0043065 (EC: IEA); GO_0043123 (EC: IDA, PMID: 15033494); GO_0043231 (EC: IDA); GO_0044548 (EC: IPI, PMID: 10913138); GO_0045087 (EC: TAS); GO_0048156 (EC: ISS); GO_0048168 (EC: IEA); GO_0048306 (EC: IDA, PMID: 10913138); GO_0048471 (EC: IDA, PMID: 12118070); GO_0048708 (EC: IEA); GO_0050786 (EC: IPI, PMID: 15033494); GO_0051384 (EC: IEA); GO_0051597 (EC: IEA); GO_0060291 (EC: IEA); GO_0071456 (EC: IEA); GO_2001015 (EC: IEA) PMID: 1998503; 2394738; 2530061; 2833519; 2964086; 3111527; 4031854; 6487634; 7566098; 7759097; 8202493; 8341667; 8701470; 8750867; 8894274; 9335118; 9519411; 9774336; 9883272; 9923610; 9925766; 10394361; 10399917; 10510252; 10531386; 10830953; 10876243; 10913138; 11264299; 11312263; 11527429; 11809917; 11888280; 11969402; 12042313; 12118070; 12351263; 12377780; 12469878; 12470955; 12477932; 12480931; 12490005; 12493777; 12505619; 12527118; 12569284; 12630517; 12636931; 12645009; 12746458; 12927678; 14530578; 14642437; 14661952; 14675567; 14699277; 14967825; 14997170; 15033494; 15178678; 15236402; 15257081; 15306236; 15489334; 15556616; 15670788; 15708543; 15781852; 15820773; 15840729; 16143320; 16189514; 16340181; 16511125; 16931519; 17008613; 17010455; 17020600; 17023485; 17043297; 17091777; 17199889; 17264538; 17348038; 17396138; 17408991; 17525977; 17536784; 17579612; 17624933; 17660747; 17661202; 17678654; 17705023; 17719207; 17726019; 17955279; 17984171; 17984926; 17984939; 18039581; 18173564; 18181515; 18193148; 18337650; 18384084; 18385926; 18445708; 18451356; 18454941; 18494933; 18552513; 18587628; 18596106; 18614943; 18706914; 18783450; 18805362; 18854308; 18939940; 18948614; 18982242; 19011512; 19042077; 19086053; 19103440; 19147496; 19183802; 19202335; 19205880; 19216510; 19220958; 19221847; 19229202; 19297317; 19307814; 19330775; 19468240; 19482672; 19487970; 19497163; 19505208; 19539717; 19558426; 19593677; 19636631; 19654082; 19671853; 19674846; 19705461; 19812958; 19910580; 19939849; 20036852; 20036866; 20042890; 20093730; 20105309; 20237496; 20351179; 20398908; 20437790; 20473040; 20509936; 20559426; 20581773; 20587415; 20591429; 20592382; 20604725; 20614004; 20628824; 20686797; 20708613; 20716661; 20947022; 20950652; 21034449; 21070816; 21079180; 21112154; 21144594; 21273622; 21293918; 21303299; 21311479; 21368691; 21376255; 21423669; 21447379; 21455324; 21458434; 21473859; 21487066; 21504113; 21553520; 21587126; 21601568; 21620650; 21628886; 21640093; 21663912; 21674567; 21688665; 21714070; 21725169; 21738758; 21779383; 21810220; 21858537; 21861214; 21861268; 21906477; 21932834; 21976236; 22011044; 22019077; 22025532; 22114731; 22177239; 22224444; 22285378; 22286170; 22286962; 22306257; 22322856; 22326439; 22348227; 22359053; 22565174; 22766253; 22782342; 22916238; 22935566; 22982200; 23030834; 23031665; 23053124; 23130680; 23141161; 23146618; 23161189; 23163123; 23169921; 23190274; 23208248; 23261835; 23262371; 23292665; 23297751; 23336432; 23378728; 23380091; 23406753; 23438158; 23523337; 23528506; 23587577; 23705829; 23713736; 23755753; 23757003; 23824909; 23889347; 24063890; 24076007; 24340553 S100 calcium binding protein B HGNC:10500 HPRD:01505 MIM:176990 S100B Bin Zhao, Yue Liu, Oliver He ERK3 ERK6 P38GAMMA PRKM12 SAPK-3 SAPK3 WEB: http://www.ncbi.nlm.nih.gov/gene MAPK12 mitogen-activated protein kinase 12 6300 22q13.33 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0000287 (EC: IDA, PMID: 10508788); GO_0004674 (EC: IDA, PMID: 15850461); GO_0004707 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12761180); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005739 (EC: IEA); GO_0005829 (EC: TAS); GO_0006351 (EC: IEA); GO_0006355 (EC: IEA); GO_0006975 (EC: TAS, PMID: 10848581); GO_0007050 (EC: TAS, PMID: 10848581); GO_0007165 (EC: TAS, PMID: 8633070); GO_0007265 (EC: TAS); GO_0007517 (EC: TAS, PMID: 8633070); GO_0018105 (EC: IDA, PMID: 15850461); GO_0042692 (EC: TAS); GO_0045445 (EC: IDA, PMID: 8633070); GO_0048011 (EC: TAS); GO_0051149 (EC: TAS) PMID: 1330687; 7566346; 8633070; 8920915; 9019171; 9169156; 9199504; 9297626; 9353289; 9564043; 9565682; 9628874; 9735171; 9771888; 9832145; 10212242; 10508788; 10567720; 10591208; 10848581; 11062067; 11062068; 11104762; 11181841; 11520933; 11741894; 11991731; 12167088; 12171600; 12226093; 12239168; 12387894; 12429732; 12477932; 12536241; 12761180; 12915405; 14592936; 14702039; 15123239; 15158451; 15284239; 15342622; 15461802; 15489334; 15850461; 15923648; 16637659; 17081983; 17088247; 17724032; 17906618; 18559936; 19251701; 19294699; 19913121; 19953087; 20332238; 20605917; 20628086; 20804750; 21044950; 21172807; 21532888; 21862636; 21878638; 21988832; 22399296; 22522454; 22730326; 22730327; 22939629; 23602568; 24250222 mitogen-activated protein kinase 12 Ensembl:ENSG00000188130 HGNC:6874 HPRD:03868 MIM:602399 Vega:OTTHUMG00000030145 MAPK12 Bin Zhao, Yue Liu, Oliver He ATX1 D6S504E SCA1 WEB: http://www.ncbi.nlm.nih.gov/gene ATXN1 ataxin 1 6310 6p23 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0003677 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11001934); GO_0005634 (EC: IDA); GO_0005654 (EC: IDA, PMID: 12757932); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0006351 (EC: IEA); GO_0006396 (EC: NAS, PMID: 15615787); GO_0008022 (EC: IPI, PMID: 12757932); GO_0008219 (EC: IEA); GO_0008266 (EC: IDA, PMID: 11136710); GO_0008344 (EC: IEA); GO_0008542 (EC: IEA); GO_0016363 (EC: IDA, PMID: 17557114); GO_0034046 (EC: IDA, PMID: 11136710); GO_0042272 (EC: IDA, Qualifier: colocalizes_with, PMID: 15615787); GO_0042326 (EC: IEA); GO_0042405 (EC: IDA, PMID: 15615787); GO_0042802 (EC: IPI, PMID: 11001934); GO_0043231 (EC: IDA); GO_0043569 (EC: IEA); GO_0043621 (EC: IDA, PMID: 9097953); GO_0045892 (EC: IDA, PMID: 15016912); GO_0045944 (EC: IEA); GO_0051168 (EC: IDA, PMID: 15615787); GO_0060079 (EC: IEA) PMID: 1582256; 7647801; 7951322; 8358429; 8619528; 8634720; 8872471; 9097953; 9353120; 9353121; 10713882; 11001934; 11121205; 11136710; 11781699; 11804332; 11807410; 11973625; 12062018; 12093161; 12360291; 12411613; 12477932; 12659632; 12741986; 12757707; 12757932; 14574404; 14583607; 14756671; 14985428; 15016912; 15148151; 15167689; 15292212; 15300851; 15342556; 15615787; 15750336; 15824120; 15878393; 16121196; 16311891; 16380905; 16389595; 16497448; 16614004; 16713569; 16831871; 16967484; 17110330; 17127076; 17190598; 17442486; 17557114; 17646162; 17925862; 18029348; 18160752; 18166084; 18182848; 18216249; 18231590; 18337722; 18439907; 18519031; 19049837; 19208651; 19235102; 19259763; 19451621; 19500214; 19597981; 20018885; 20069235; 20097758; 20132795; 20220018; 20301363; 20308783; 20379614; 20477910; 20936779; 21302343; 21315774; 21475249; 21835928; 22330095; 22491195; 22511762; 22666429; 22780124; 22916034; 23197749; 23275563; 23294540; 23377640; 23528090; 23536093; 23634774; 23719381; 23760502; 24326307 ataxin 1 Ensembl:ENSG00000124788 HGNC:10548 HPRD:03333 MIM:601556 Vega:OTTHUMG00000014303 ATXN1 Bin Zhao, Yue Liu, Oliver He GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF WEB: http://www.ncbi.nlm.nih.gov/gene CCL2 chemokine (C-C motif) ligand 2 6347 17q11.2-q12 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000165 (EC: IMP); GO_0001525 (EC: TAS, PMID: 18334747); GO_0001666 (EC: IEA); GO_0001938 (EC: IEA); GO_0002548 (EC: IDA, PMID: 12207323); GO_0004672 (EC: TAS, PMID: 9973507); GO_0005102 (EC: TAS, PMID: 10542238); GO_0005576 (EC: IDA); GO_0005576 (EC: TAS); GO_0005615 (EC: IEA); GO_0005737 (EC: IEA); GO_0006468 (EC: TAS, PMID: 9670957); GO_0006874 (EC: IEA); GO_0006935 (EC: TAS, PMID: 10623817); GO_0006954 (EC: IDA); GO_0006959 (EC: TAS, PMID: 9548499); GO_0006987 (EC: TAS); GO_0007010 (EC: IDA, PMID: 10072545); GO_0007155 (EC: TAS, PMID: 10198043); GO_0007165 (EC: NAS, PMID: 10770925); GO_0007166 (EC: TAS, PMID: 9548499); GO_0007179 (EC: IEA); GO_0007186 (EC: TAS, PMID: 10542238); GO_0007187 (EC: TAS, PMID: 10770925); GO_0007259 (EC: TAS, PMID: 9670957); GO_0007568 (EC: IEA); GO_0008009 (EC: IEA); GO_0008201 (EC: IEA); GO_0008360 (EC: IDA, PMID: 10072545); GO_0009408 (EC: IEA); GO_0009612 (EC: IEA); GO_0009617 (EC: IEP, PMID: 16034137); GO_0009887 (EC: TAS, PMID: 9364936); GO_0010332 (EC: IEA); GO_0010574 (EC: IEA); GO_0010759 (EC: IEA); GO_0014823 (EC: IEA); GO_0016525 (EC: IEA); GO_0019079 (EC: TAS, PMID: 10985244); GO_0019221 (EC: IDA, PMID: 12207323); GO_0019725 (EC: TAS, PMID: 18334747); GO_0030593 (EC: IEA); GO_0030968 (EC: TAS); GO_0031100 (EC: IEA); GO_0031663 (EC: IDA); GO_0031727 (EC: ISS); GO_0031727 (EC: TAS, PMID: 18021937); GO_0032570 (EC: IEA); GO_0033552 (EC: IEA); GO_0034351 (EC: IDA, PMID: 12753088); GO_0035684 (EC: ISS); GO_0042493 (EC: IEA); GO_0043025 (EC: IEA); GO_0043200 (EC: IEA); GO_0043491 (EC: IMP); GO_0043524 (EC: IDA, PMID: 12753088); GO_0043615 (EC: IDA, PMID: 12271471); GO_0044267 (EC: TAS); GO_0044344 (EC: IEP, PMID: 9407497); GO_0045471 (EC: IEA); GO_0046677 (EC: IEA); GO_0048010 (EC: IEA); GO_0048246 (EC: IDA, PMID: 12207323); GO_0048247 (EC: IEA); GO_0050806 (EC: IEA); GO_0050870 (EC: ISS); GO_0051384 (EC: IEA); GO_0051770 (EC: ISS); GO_0060137 (EC: IEA); GO_0070098 (EC: IEA); GO_0071222 (EC: ISS); GO_0071346 (EC: IEP, PMID: 9407497); GO_0071346 (EC: ISS); GO_0071347 (EC: IEP, PMID: 9407497); GO_0071347 (EC: ISS); GO_0071356 (EC: IEP, PMID: 9407497); GO_0071356 (EC: ISS); GO_0071407 (EC: IDA); GO_0090265 (EC: IEA); GO_2000427 (EC: ISS); GO_2000502 (EC: IDA, PMID: 7545673) PMID: 1661560; 1857712; 2004761; 2071154; 2322286; 2357211; 2465924; 2501656; 2513477; 2518726; 2648385; 2923622; 7545673; 7651403; 8051410; 8107690; 8195247; 8627182; 8631787; 8639605; 8642344; 8898111; 8989326; 9287323; 9364936; 9405404; 9407497; 9501225; 9548499; 9558113; 9670957; 9789057; 9792375; 9792674; 9837883; 9973507; 10068657; 10072545; 10198043; 10453044; 10477718; 10529171; 10542238; 10587439; 10623817; 10644332; 10706668; 10734104; 10751368; 10770925; 10918580; 10982368; 10985244; 11083865; 11145723; 11154208; 11313374; 11350939; 11500196; 11544456; 11750041; 11751881; 11776402; 11844145; 11878903; 11912219; 11929421; 11989790; 11999660; 12009356; 12022754; 12067898; 12078856; 12082252; 12089333; 12093796; 12117737; 12127997; 12149192; 12183528; 12186702; 12195705; 12204371; 12207323; 12234797; 12239249; 12271471; 12351486; 12358851; 12372466; 12374865; 12391099; 12391196; 12393171; 12397639; 12399623; 12408680; 12410798; 12413001; 12419245; 12443832; 12460032; 12462338; 12470469; 12473373; 12477932; 12485413; 12488502; 12505750; 12520153; 12520365; 12540965; 12632067; 12651071; 12665582; 12724308; 12753088; 12758167; 12787135; 12805068; 12826189; 12826377; 12846738; 12904997; 12944979; 12946945; 12957789; 12960255; 13679391; 14517168; 14517792; 14550782; 14571188; 14576080; 14597108; 14602575; 14620921; 14647058; 14651522; 14660607; 14687706; 14733721; 14767014; 15005768; 15016614; 15022320; 15033992; 15034225; 15041705; 15067078; 15077296; 15081318; 15082170; 15110609; 15115316; 15123743; 15135805; 15167690; 15188361; 15191525; 15191888; 15191916; 15194470; 15203564; 15226634; 15257681; 15280531; 15288699; 15296827; 15302103; 15308783; 15312962; 15349727; 15389752; 15466648; 15468376; 15481145; 15488313; 15489334; 15492853; 15529362; 15545821; 15579297; 15599324; 15602730; 15607028; 15611878; 15627719; 15630704; 15654958; 15677312; 15722361; 15740484; 15745922; 15780578; 15832427; 15848524; 15866653; 15880317; 15883814; 15900302; 15919935; 15976326; 15979992; 16003740; 16004967; 16009177; 16009638; 16020745; 16034137; 16050950; 16078996; 16095529; 16105652; 16116069; 16129702; 16160188; 16164699; 16195477; 16204411; 16206161; 16206198; 16213182; 16214031; 16230097; 16249002; 16278381; 16280328; 16280979; 16307829; 16309586; 16318581; 16351713; 16352737; 16356504; 16358960; 16359995; 16362156; 16397773; 16415174; 16427785; 16436595; 16439461; 16439481; 16439891; 16445900; 16474202; 16479072; 16504689; 16516290; 16518346; 16524739; 16597919; 16609683; 16631114; 16636247; 16636603; 16672419; 16697212; 16697654; 16697675; 16705739; 16712788; 16719905; 16730843; 16733654; 16741188; 16750572; 16751386; 16781696; 16795034; 16802342; 16804844; 16814297; 16825597; 16828028; 16835702; 16867220; 16872505; 16873204; 16903979; 16934270; 16939660; 16980310; 16988194; 16997300; 17008880; 17032917; 17046994; 17052731; 17062130; 17065190; 17082648; 17091019; 17098977; 17138827; 17169533; 17187019; 17202846; 17207568; 17218539; 17262819; 17280738; 17283105; 17284607; 17307163; 17322498; 17364892; 17376903; 17379849; 17384985; 17390372; 17395051; 17404035; 17407231; 17416748; 17417600; 17424890; 17426779; 17431224; 17458901; 17465499; 17485071; 17486299; 17490777; 17495598; 17522215; 17525255; 17530707; 17582674; 17596666; 17625600; 17694504; 17700210; 17703277; 17703412; 17704101; 17706208; 17707134; 17728497; 17763208; 17767550; 17804911; 17822317; 17884268; 17886678; 17917677; 17920586; 17922439; 17928143; 17934860; 17940904; 17943082; 17949278; 17968528; 17968796; 17975143; 17977907; 17982227; 18021937; 18022660; 18032547; 18040846; 18042260; 18055544; 18060801; 18061474; 18069114; 18069417; 18070228; 18074388; 18089573; 18093183; 18093816; 18158188; 18164957; 18172114; 18186797; 18190912; 18191726; 18203956; 18205260; 18208975; 18230355; 18242157; 18266131; 18266972; 18270300; 18271757; 18272603; 18274642; 18276775; 18284633; 18310503; 18314120; 18334747; 18347511; 18371304; 18373164; 18381789; 18395486; 18395775; 18402383; 18436581; 18439751; 18443042; 18458846; 18469140; 18495743; 18506929; 18508485; 18515987; 18521742; 18522702; 18525219; 18528529; 18570214; 18611860; 18615095; 18619701; 18623207; 18636124; 18637012; 18646053; 18651322; 18656701; 18660381; 18660489; 18665050; 18678243; 18684531; 18690522; 18702087; 18702954; 18710415; 18718072; 18758234; 18762729; 18784079; 18790652; 18804983; 18808740; 18818748; 18824549; 18829011; 18837094; 18855195; 18937353; 18940815; 18953909; 18954908; 18962899; 18976655; 18976766; 18977211; 18996102; 18996288; 19001328; 19002595; 19009499; 19014891; 19017462; 19019335; 19020833; 19032843; 19032844; 19032966; 19034671; 19048368; 19055601; 19072670; 19074885; 19092169; 19099590; 19099689; 19100389; 19115220; 19132243; 19136823; 19147409; 19148342; 19152916; 19154405; 19155472; 19156168; 19166999; 19167353; 19168721; 19170716; 19176388; 19185603; 19187096; 19211266; 19215923; 19218821; 19228389; 19233564; 19234509; 19242604; 19247692; 19247801; 19258635; 19258923; 19267279; 19277984; 19281798; 19287949; 19288202; 19298002; 19317061; 19327225; 19328242; 19332042; 19347053; 19357773; 19360344; 19361458; 19364494; 19371341; 19373627; 19376162; 19379593; 19392835; 19409809; 19411748; 19420105; 19423540; 19426980; 19439012; 19441883; 19441886; 19443842; 19446037; 19450143; 19458908; 19465691; 19479998; 19494437; 19496969; 19506371; 19524871; 19525388; 19525846; 19526283; 19527514; 19555664; 19558503; 19565503; 19573434; 19576791; 19587356; 19587833; 19625220; 19628738; 19632522; 19639050; 19641159; 19642141; 19642908; 19644155; 19646633; 19658300; 19664934; 19668598; 19706805; 19711822; 19720836; 19726280; 19729601; 19736361; 19755790; 19755933; 19760754; 19773451; 19777601; 19781192; 19781803; 19782713; 19819989; 19822078; 19828696; 19833726; 19844201; 19851831; 19864434; 19865101; 19866475; 19881959; 19885629; 19893256; 19902472; 19904283; 19906815; 19913121; 19923858; 19926874; 19929093; 19938194; 19941075; 19942750; 19948975; 19957783; 19995900; 20000039; 20004457; 20016208; 20029197; 20029451; 20031554; 20038977; 20040767; 20041183; 20056091; 20056178; 20087947; 20097750; 20100200; 20102417; 20111728; 20121167; 20125127; 20137666; 20138641; 20140679; 20177146; 20179890; 20187772; 20193755; 20196868; 20221866; 20228199; 20231199; 20237358; 20237496; 20299238; 20299783; 20339010; 20339966; 20349326; 20351714; 20364004; 20368224; 20370601; 20374368; 20389059; 20406462; 20406964; 20414371; 20416077; 20423879; 20430117; 20431065; 20432237; 20437404; 20438785; 20442634; 20446021; 20449800; 20449809; 20451256; 20452482; 20484496; 20485444; 20488574; 20497022; 20503287; 20504881; 20523065; 20526368; 20531015; 20540976; 20546673; 20563852; 20570966; 20573518; 20576301; 20602615; 20605053; 20607592; 20610178; 20617559; 20625355; 20628086; 20634732; 20637631; 20650649; 20673868; 20677014; 20681057; 20692455; 20725607; 20726788; 20737475; 20811626; 20818133; 20825374; 20859200; 20861640; 20880493; 20934684; 20947712; 20950459; 20960176; 20962626; 20965747; 21033620; 21037509; 21072187; 21073393; 21087336; 21097527; 21102463; 21107756; 21114970; 21134984; 21135144; 21148795; 21181544; 21183736; 21187454; 21190865; 21199725; 21220697; 21224075; 21247529; 21251883; 21264298; 21264360; 21327296; 21328336; 21354997; 21361908; 21368227; 21376205; 21383955; 21384169; 21385934; 21397653; 21401388; 21413027; 21423810; 21447688; 21450101; 21486440; 21486949; 21504590; 21527853; 21529268; 21529952; 21532752; 21551367; 21556333; 21569455; 21574823; 21610567; 21615418; 21620438; 21627744; 21654748; 21691937; 21701898; 21726903; 21734368; 21744268; 21760952; 21774078; 21787749; 21799302; 21851000; 21855541; 21858104; 21859809; 21868018; 21868706; 21883707; 21890375; 21898402; 21900689; 21906274; 21910857; 21920519; 21924076; 21930770; 21951843; 21951854; 21961038; 21975431; 21991356; 21992868; 22026334; 22037282; 22037980; 22059352; 22081934; 22117412; 22117820; 22125641; 22131127; 22132892; 22138288; 22142522; 22147846; 22152380; 22159219; 22183310; 22197827; 22203484; 22210436; 22226505; 22240432; 22265030; 22276574; 22288595; 22300682; 22301094; 22303443; 22319587; 22319627; 22321225; 22362506; 22377751; 22378888; 22381103; 22384203; 22396538; 22412388; 22420243; 22422499; 22425139; 22427564; 22448134; 22466290; 22472119; 22476561; 22484917; 22487967; 22490648; 22493691; 22541401; 22543850; 22554651; 22558273; 22612293; 22617682; 22619484; 22641100; 22664781; 22669976; 22691208; 22694757; 22697070; 22707193; 22711527; 22721162; 22729037; 22733495; 22739041; 22750227; 22752804; 22759858; 22762377; 22763298; 22766373; 22815949; 22823210; 22848642; 22857869; 22859936; 22861370; 22868806; 22927430; 22942263; 22961048; 22980664; 22981148; 22985557; 22989614; 22992722; 23007133; 23017229; 23037589; 23039889; 23069648; 23090289; 23128233; 23135705; 23143679; 23151275; 23154550; 23160182; 23161207; 23166687; 23180368; 23185481; 23185512; 23192155; 23206327; 23211090; 23224211; 23255244; 23274856; 23300810; 23303452; 23349788; 23350010; 23352833; 23375122; 23383162; 23402987; 23408426; 23416968; 23418647; 23429817; 23434371; 23454776; 23474119; 23490412; 23529020; 23542734; 23548612; 23549806; 23555755; 23557387; 23559389; 23583295; 23629827; 23657965; 23686489; 23704830; 23712703; 23762283; 23770363; 23782302; 23816715; 23831464; 23845726; 23886148; 23887394; 23890452; 23939977; 23954399; 23982944; 23999007; 24058270; 24077340; 24078580; 24260304; 24273921 chemokine (C-C motif) ligand 2 Ensembl:ENSG00000108691 HGNC:10618 HPRD:01149 MIM:158105 Vega:OTTHUMG00000132887 CCL2 Bin Zhao, Yue Liu, Oliver He CD362 HSPG HSPG1 SYND2 WEB: http://www.ncbi.nlm.nih.gov/gene SDC2 syndecan 2 6383 8q22-q23 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0001523 (EC: TAS); GO_0001666 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11356864); GO_0005796 (EC: TAS); GO_0005886 (EC: TAS); GO_0005975 (EC: TAS); GO_0006024 (EC: TAS); GO_0006027 (EC: TAS); GO_0007603 (EC: TAS); GO_0008092 (EC: IEA); GO_0008150 (EC: ND); GO_0016021 (EC: IEA); GO_0030165 (EC: IPI, PMID: 18256285); GO_0030198 (EC: TAS); GO_0030203 (EC: TAS); GO_0030204 (EC: TAS); GO_0031000 (EC: IEA); GO_0042060 (EC: IEA); GO_0043025 (EC: IEA); GO_0043202 (EC: TAS); GO_0044281 (EC: TAS); GO_0048813 (EC: IEA); GO_0048814 (EC: ISS) PMID: 1315572; 2523388; 2745554; 2948951; 7524669; 7551962; 7690138; 8157651; 8187643; 8570206; 8832397; 8889549; 8997243; 9111037; 9244383; 9259269; 9342064; 9391086; 9660868; 9869645; 10375199; 10446183; 10497173; 10704377; 10734053; 10772816; 11018053; 11023673; 11024024; 11161813; 11356864; 11373281; 11567105; 11580899; 12036876; 12055189; 12200971; 12477932; 12676536; 12708751; 12860416; 12860968; 12885232; 14527339; 14674716; 14702039; 14976204; 14999018; 15183101; 15297422; 15489334; 15846369; 15936998; 16157597; 16253987; 16303743; 16440330; 16817962; 16982797; 16997272; 17035092; 17261577; 17457918; 17516498; 17623663; 18032547; 18093920; 18256285; 18342939; 18599487; 18716610; 19073173; 19086053; 19179614; 19288017; 19322201; 19383343; 19450993; 19641225; 19786981; 19822079; 19913121; 19962968; 20006588; 20379614; 20485444; 20628086; 20683009; 20929862; 21036168; 21139048; 21148276; 21289173; 21317913; 21482826; 21569759; 21813734; 21963094; 21987572; 21988832; 22170634; 22227189; 22238310; 22437834; 22471946; 22493442; 22550000; 22558273; 22745764; 22881146; 23000965; 23297089; 23333331; 23455922; 23736812; 23747112 syndecan 2 Ensembl:ENSG00000169439 HGNC:10659 HPRD:00803 MIM:142460 Vega:OTTHUMG00000164689 SDC2 Bin Zhao, Yue Liu, Oliver He JNKK JNKK1 MAPKK4 MEK4 MKK4 PRKMK4 SAPKK-1 SAPKK1 SEK1 SERK1 SKK1 WEB: http://www.ncbi.nlm.nih.gov/gene MAP2K4 mitogen-activated protein kinase kinase 4 6416 17p12 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0002224 (EC: TAS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004672 (EC: TAS, PMID: 7716521); GO_0004674 (EC: IEA); GO_0004713 (EC: IEA); GO_0005515 (EC: IPI, PMID: 9808624); GO_0005524 (EC: IEA); GO_0005634 (EC: IEA); GO_0005829 (EC: TAS); GO_0006915 (EC: IEA); GO_0007165 (EC: TAS, PMID: 7716521); GO_0007254 (EC: TAS); GO_0008545 (EC: IEA); GO_0031435 (EC: IEA); GO_0032839 (EC: IEA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0038095 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0043204 (EC: IEA); GO_0043525 (EC: IEA); GO_0045087 (EC: TAS); GO_0045740 (EC: IEA); GO_0051403 (EC: TAS); GO_0071260 (EC: IEP, PMID: 19593445); GO_0072709 (EC: IEA) PMID: 7716521; 7839144; 7997270; 8631303; 8755474; 8786147; 9002521; 9006895; 9162092; 9182538; 9207092; 9331070; 9405400; 9582321; 9622070; 9661668; 9712898; 9761781; 9808624; 9841871; 10187804; 10489373; 10521444; 10523642; 10620019; 10713157; 10715136; 10969079; 11062067; 11090355; 11104681; 11279118; 11306453; 11562357; 11707464; 11754110; 11836244; 12189133; 12220515; 12223490; 12228228; 12368275; 12391307; 12429732; 12456688; 12477932; 12556533; 12659851; 12714585; 12730213; 12788955; 13130464; 14500727; 14504284; 14511403; 14581471; 14661062; 14702039; 14716300; 15256484; 15258908; 15262961; 15276183; 15299005; 15299019; 15328343; 15496400; 15592684; 15623633; 15670787; 15737736; 15866172; 15911620; 15998799; 16167336; 16197369; 16339111; 16344560; 16388335; 16472679; 16533805; 16627982; 16709574; 16802349; 16964394; 17009014; 17110930; 17158870; 17178861; 17322004; 17389591; 17541429; 17675521; 17906693; 18337456; 18408005; 18436711; 18713996; 19001375; 19012245; 19265040; 19294699; 19302196; 19351724; 19351817; 19513509; 19593445; 19610067; 19638505; 19737936; 19782076; 19861690; 20156194; 20309881; 20554746; 20732303; 20801953; 21030692; 21048031; 21333379; 21372598; 21487811; 21518142; 21575258; 21638028; 21702039; 21822214; 21832049; 21896780; 21900206; 21915030; 21925502; 21988832; 22154052; 22154358; 22158075; 22335172; 22366412; 22526163; 22535895; 22730327; 22828509; 22952603; 23299404; 23355465; 23653187; 23877919; 23921907; 23960075 mitogen-activated protein kinase kinase 4 Ensembl:ENSG00000065559 HGNC:6844 HPRD:03213 MIM:601335 Vega:OTTHUMG00000178267 MAP2K4 Bin Zhao, Yue Liu, Oliver He 2PP2A I2PP2A IGAAD IPP2A2 PHAPII TAF-I TAF-IBETA WEB: http://www.ncbi.nlm.nih.gov/gene SET SET nuclear oncogene 6418 RP11-216B9.3 9q34 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000278 (EC: TAS); GO_0003677 (EC: IEA); GO_0004864 (EC: TAS, PMID: 8626647); GO_0005515 (EC: IPI, PMID: 11909973); GO_0005634 (EC: IDA, PMID: 11555662); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA, PMID: 11909973); GO_0005783 (EC: IDA, PMID: 11555662); GO_0005829 (EC: IEA); GO_0006260 (EC: TAS, PMID: 7753797); GO_0006334 (EC: IEA); GO_0006337 (EC: TAS, PMID: 11555662); GO_0006913 (EC: NAS, PMID: 11555662); GO_0008601 (EC: TAS, PMID: 11555662); GO_0010467 (EC: TAS); GO_0016070 (EC: TAS); GO_0016071 (EC: TAS); GO_0035067 (EC: TAS, PMID: 11555662); GO_0042393 (EC: TAS, PMID: 11555662); GO_0043086 (EC: TAS, PMID: 8626647); GO_0043234 (EC: IDA, PMID: 11909973); GO_0043524 (EC: IGI, PMID: 18374643); GO_0045892 (EC: IDA, PMID: 19343227); GO_0048471 (EC: IDA, PMID: 11555662); GO_0050790 (EC: TAS, PMID: 11555662) PMID: 1630450; 7753797; 8125298; 8131851; 8192856; 8294483; 8626647; 9353299; 9773788; 10390352; 10490631; 11018049; 11073993; 11076863; 11163245; 11231286; 11555662; 11741927; 11909973; 11978794; 12107410; 12407107; 12444089; 12477932; 12524539; 12628186; 14612398; 14671643; 14759373; 15100215; 15136563; 15146197; 15164053; 15173575; 15239126; 15342556; 15489334; 15489336; 15556635; 15592452; 15642345; 15840729; 15930275; 15931263; 16061203; 16162853; 16189514; 16212417; 16226712; 16286244; 16381901; 16474839; 16541025; 16712791; 16818237; 16823850; 16861234; 16916647; 17008916; 17034827; 17065150; 17081983; 17142970; 17245428; 17296573; 17309103; 17353931; 17360516; 17529993; 17608644; 17620317; 17643375; 17868381; 17875674; 18096310; 18299449; 18374643; 18457437; 18591933; 18649364; 18685082; 18781797; 18809386; 18931446; 19028839; 19059912; 19166587; 19234487; 19322201; 19343227; 19358706; 19471022; 19615732; 19738201; 19836239; 19900756; 20195357; 20360068; 20634891; 20693670; 20800572; 20876349; 21044950; 21139048; 21156847; 21209461; 21289314; 21319273; 21419339; 21515671; 21693764; 21720744; 21725597; 21800051; 21806989; 21844565; 21890473; 21906983; 21911363; 21940793; 21963094; 21987572; 21988832; 22053931; 22127260; 22133779; 22143534; 22174317; 22466417; 22505724; 22677993; 22739068; 22796192; 22863883; 22939629; 23000965; 23106910; 23134341; 23195690; 23233674; 23251465; 23374587; 23463506; 23568457; 23667531; 23691099; 23862649; 24144296; 24244333; 24250222 SET nuclear oncogene Ensembl:ENSG00000119335 HGNC:10760 HPRD:09023 MIM:600960 Vega:OTTHUMG00000020755 SET Bin Zhao, Yue Liu, Oliver He SHC SHCA WEB: http://www.ncbi.nlm.nih.gov/gene SHC1 SHC (Src homology 2 domain containing) transforming protein 1 6464 RP11-307C12.1 1q21 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000165 (EC: IDA, PMID: 14676841); GO_0000187 (EC: IDA, PMID: 14676841); GO_0001525 (EC: IEA); GO_0004713 (EC: TAS); GO_0005068 (EC: TAS, PMID: 14676841); GO_0005154 (EC: ISS); GO_0005158 (EC: IPI, PMID: 7537849); GO_0005159 (EC: IPI, PMID: 7541045); GO_0005168 (EC: IPI, PMID: 15488758); GO_0005515 (EC: IPI, PMID: 11827484); GO_0005543 (EC: TAS, PMID: 14676841); GO_0005759 (EC: IEA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 14676841); GO_0005886 (EC: TAS); GO_0006987 (EC: TAS); GO_0007173 (EC: TAS); GO_0007176 (EC: TAS, PMID: 1623525); GO_0007265 (EC: TAS); GO_0007507 (EC: IEA); GO_0007596 (EC: TAS); GO_0008284 (EC: NAS, PMID: 14676841); GO_0008286 (EC: ISS); GO_0008286 (EC: TAS); GO_0008543 (EC: TAS); GO_0016337 (EC: IEA); GO_0018108 (EC: TAS); GO_0030168 (EC: TAS); GO_0030968 (EC: TAS); GO_0031532 (EC: IEA); GO_0038095 (EC: TAS); GO_0040008 (EC: IEA); GO_0044267 (EC: TAS); GO_0045087 (EC: TAS); GO_0045740 (EC: ISS); GO_0046875 (EC: IPI, PMID: 12925710); GO_0048011 (EC: TAS); GO_0050900 (EC: TAS); GO_0070435 (EC: ISS) PMID: 1623525; 7473762; 7499194; 7506413; 7514169; 7515480; 7516469; 7518560; 7520523; 7524086; 7535773; 7537361; 7537740; 7537849; 7541035; 7541045; 7542991; 7544002; 7544443; 7556090; 7559478; 7559507; 7635484; 7650013; 7657612; 7675451; 7731718; 7739560; 7791787; 7798267; 7806213; 7929214; 7933095; 7953556; 7961936; 7970715; 8035825; 8084588; 8112292; 8125298; 8155326; 8183561; 8195171; 8226808; 8294403; 8400282; 8491186; 8493579; 8524391; 8541543; 8557643; 8577769; 8610109; 8617812; 8621719; 8626541; 8628261; 8631299; 8631894; 8633037; 8643566; 8643691; 8647288; 8656061; 8662733; 8662748; 8662998; 8702728; 8723348; 8761298; 8776723; 8810325; 8874179; 8887653; 8890167; 8918464; 8939605; 8940017; 8940081; 8943228; 8950973; 8995379; 9045663; 9045692; 9047383; 9047384; 9049300; 9058724; 9083103; 9096689; 9121430; 9122198; 9126968; 9129019; 9130710; 9148935; 9174053; 9192859; 9202037; 9209414; 9223670; 9233773; 9234717; 9325171; 9344843; 9346925; 9378963; 9388490; 9434624; 9446569; 9461587; 9488479; 9541596; 9544989; 9614102; 9617486; 9632636; 9659899; 9660480; 9660833; 9685404; 9690470; 9694850; 9710204; 9710588; 9716598; 9733714; 9741627; 9756944; 9804835; 9824671; 9837978; 9856458; 9872323; 9886492; 9927207; 10025673; 10037694; 10049786; 10080542; 10085134; 10086341; 10092678; 10194451; 10224114; 10319320; 10340378; 10382761; 10457218; 10477722; 10477741; 10482988; 10559276; 10570290; 10595738; 10602027; 10623845; 10629055; 10635327; 10650943; 10652211; 10662798; 10675333; 10681566; 10704825; 10708759; 10748054; 10749680; 10764799; 10783152; 10790433; 10803466; 10816433; 10822173; 10891441; 10896916; 10900203; 10921922; 10964917; 10971656; 10996427; 11027663; 11044453; 11071635; 11075717; 11094073; 11287610; 11302736; 11342545; 11349134; 11370743; 11408594; 11432829; 11505033; 11520933; 11533253; 11607835; 11694516; 11707390; 11707404; 11707405; 11714803; 11724572; 11773443; 11782427; 11825908; 11827484; 11854294; 11855827; 11877420; 11884411; 11884620; 11888936; 11896612; 11903040; 11948181; 11950700; 11964172; 11980671; 12009895; 12024011; 12048194; 12052829; 12069755; 12114320; 12135708; 12237775; 12400011; 12419535; 12441060; 12446583; 12446789; 12477932; 12485888; 12522270; 12577067; 12586295; 12589038; 12789267; 12808090; 12871937; 12898421; 12925710; 14530863; 14573619; 14665640; 14676841; 14702039; 14749389; 14764897; 14982882; 14983012; 14990987; 15036421; 15094067; 15226408; 15308584; 15316024; 15470047; 15485499; 15488758; 15489334; 15562031; 15588985; 15592455; 15657067; 15688026; 15705774; 15753984; 15812354; 15888547; 15951569; 15992607; 16034442; 16099422; 16113100; 16135792; 16170380; 16186108; 16189514; 16219545; 16257509; 16273093; 16436505; 16481327; 16487929; 16519809; 16729043; 16756945; 16825188; 16843263; 16934220; 17001306; 17081113; 17081983; 17158237; 17167775; 17207965; 17380301; 17906149; 17908971; 17938255; 17998013; 18032526; 18067454; 18093973; 18271526; 18279888; 18385518; 18420583; 18480379; 18504439; 18611262; 18660489; 18840094; 19055724; 19172738; 19229850; 19380743; 19383602; 19531499; 19696221; 19826412; 19828641; 19884766; 19889638; 19889727; 20061561; 20111892; 20226758; 20354186; 20379614; 20534722; 20624904; 20637729; 20667496; 20676142; 20697350; 20739287; 20842738; 21139048; 21206972; 21264241; 21439852; 21612602; 21616139; 21706016; 21778425; 21817106; 21828072; 21900206; 21906983; 21933910; 21983898; 22020565; 22039050; 22096252; 22100252; 22101521; 22561705; 22641095; 22661506; 22974441; 23033271; 23267066; 23277357; 23524280; 23529764; 23535732; 23584453; 23606925; 23689140; 23799367; 23815759; 23956138; 23993977; 24250222 SHC (Src homology 2 domain containing) transforming protein 1 Ensembl:ENSG00000160691 HGNC:10840 HPRD:02780 MIM:600560 Vega:OTTHUMG00000037295 SHC1 Bin Zhao, Yue Liu, Oliver He GD3S SIAT8 SIAT8-A SIAT8A ST8SiaI WEB: http://www.ncbi.nlm.nih.gov/gene ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 6489 12p12.1-p11.2 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0003828 (EC: IEA); GO_0005975 (EC: TAS, PMID: 8195250); GO_0006486 (EC: IEA); GO_0006688 (EC: TAS, PMID: 8195250); GO_0008284 (EC: IEA); GO_0008373 (EC: TAS, PMID: 8195250); GO_0016021 (EC: TAS, PMID: 8195250); GO_0030173 (EC: IEA); GO_0034605 (EC: IEA); GO_0097503 (EC: TAS, PMID: 8195250) PMID: 7901202; 7937974; 8058740; 8195250; 8631981; 8786103; 8889548; 9287216; 10766765; 11849746; 12477932; 12818424; 15175338; 15196944; 15319364; 15489334; 16120058; 16481330; 16862187; 17913261; 18261989; 18348864; 18612409; 18690648; 19125296; 19280063; 19335207; 19428123; 19956670; 20379614; 20708005; 20889649; 22885356; 23725790 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 Ensembl:ENSG00000111728 HGNC:10869 HPRD:03078 MIM:601123 Vega:OTTHUMG00000169098 ST8SIA1 Bin Zhao, Yue Liu, Oliver He D12S53E ME20 ME20-M ME20M P1 P100 PMEL17 SI SIL SILV gp100 WEB: http://www.ncbi.nlm.nih.gov/gene PMEL premelanosome protein 6490 12q13-q14 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 15695812); GO_0005576 (EC: IEA); GO_0005789 (EC: IDA, PMID: 15695812); GO_0005794 (EC: IDA, PMID: 15695812); GO_0005886 (EC: TAS, PMID: 8179825); GO_0016021 (EC: IEA); GO_0032438 (EC: IDA, PMID: 11694580); GO_0032585 (EC: IDA, PMID: 11694580); GO_0042438 (EC: IEA); GO_0042470 (EC: IDA, PMID: 15096515) PMID: 1922059; 1924386; 2255914; 7519602; 8022805; 8179825; 8592076; 8617263; 8739560; 9176405; 9222283; 9586889; 9743519; 10504440; 11266471; 11549113; 11694580; 12135425; 12477932; 12643545; 12732614; 12819038; 12925214; 14632201; 14702039; 15001714; 15096515; 15489334; 15695812; 16344560; 16492709; 16516837; 16682408; 16704461; 16760433; 17081065; 17303571; 17625594; 17991747; 18029348; 18181974; 18337837; 18463683; 18552823; 18563784; 19017974; 19047044; 19666488; 19840945; 19884326; 20231267; 21106765; 21148556; 21247888; 21949659; 21993558; 21993592; 22092386; 22613716; 22951725; 23389629; 23452376; 23643172; 23754390 premelanosome protein Ensembl:ENSG00000185664 HGNC:10880 HPRD:01117 MIM:155550 Vega:OTTHUMG00000170573 PMEL Bin Zhao, Yue Liu, Oliver He EMC19 OCP-II OCP2 SKP1A TCEB1L p19A WEB: http://www.ncbi.nlm.nih.gov/gene SKP1 S-phase kinase-associated protein 1 6500 5q31 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0000082 (EC: TAS); GO_0000086 (EC: TAS); GO_0000278 (EC: TAS); GO_0004842 (EC: IDA); GO_0005515 (EC: IPI, PMID: 11099048); GO_0005654 (EC: TAS); GO_0005829 (EC: TAS); GO_0007219 (EC: TAS); GO_0016032 (EC: TAS); GO_0016567 (EC: IDA, PMID: 15103331); GO_0019005 (EC: IDA, PMID: 15103331); GO_0031145 (EC: TAS); GO_0031146 (EC: IDA, PMID: 15103331); GO_0031467 (EC: IDA); GO_0031519 (EC: IDA, Qualifier: colocalizes_with, PMID: 16943429); GO_0035518 (EC: IDA, PMID: 16943429); GO_0051437 (EC: TAS); GO_0051439 (EC: TAS) PMID: 7553852; 7558018; 8051045; 8530064; 8646875; 8706131; 8912791; 9031623; 9430629; 9636170; 9660940; 9663463; 9736735; 9827542; 9857061; 9858587; 9872132; 9990852; 10023660; 10066435; 10074433; 10228155; 10230406; 10230407; 10321728; 10508920; 10514433; 10531035; 10531037; 10559858; 10559916; 10644755; 10648623; 10713156; 10918611; 10973499; 11027288; 11099048; 11231585; 11245432; 11337588; 11359933; 11389839; 11483504; 11565034; 11585921; 11689688; 11717410; 11850407; 11956208; 11961546; 12117534; 12140560; 12165731; 12417738; 12477932; 12481031; 12504025; 12504026; 12609982; 12628165; 12665572; 12679038; 12684064; 12717421; 12746458; 12791267; 12820959; 12840033; 12904573; 12963825; 14603323; 14685242; 14702039; 14706645; 14743216; 14752276; 15070733; 15103331; 15109709; 15118074; 15145941; 15280393; 15342634; 15452136; 15456869; 15469821; 15469984; 15489334; 15635413; 15640526; 15772084; 15966899; 16009132; 16123585; 16169070; 16196087; 16275325; 16278047; 16357137; 16501598; 16503656; 16682006; 16705156; 16714087; 16759355; 16880511; 16943429; 16979657; 17081987; 17098746; 17205132; 17215248; 17274640; 17283138; 17290223; 17314511; 17353931; 17389369; 17389604; 17434132; 17463251; 17494702; 17569795; 17704768; 17998335; 18071316; 18094045; 18203720; 18239684; 18247557; 18284940; 18378770; 18426905; 18660753; 18775313; 18781797; 18784078; 18784254; 18809579; 18818696; 19061640; 19066453; 19159283; 19193609; 19270694; 19295130; 19322201; 19398581; 19471022; 19509332; 19615732; 19762596; 19762597; 19776120; 19786724; 19828458; 19933270; 19996097; 20041211; 20057081; 20160477; 20181953; 20181957; 20360068; 20379614; 20404110; 20473970; 20484041; 20668394; 20832730; 21139048; 21145461; 21169563; 21205095; 21249194; 21378169; 21402913; 21466614; 21565611; 21572392; 21572988; 21620836; 21640084; 21726808; 21757720; 21778237; 21890473; 21906983; 21915095; 21952639; 21963094; 21988832; 22053931; 22113614; 22190034; 22205206; 22205987; 22242598; 22268729; 22295074; 22310285; 22325352; 22388891; 22399757; 22405651; 22464731; 22474075; 22479149; 22505724; 22590978; 22632967; 22660580; 22669845; 22730322; 22761574; 22767593; 22939629; 22952844; 22972877; 22975506; 23000965; 23027877; 23045529; 23086937; 23108047; 23261596; 23324393; 23383273; 23438482; 23455922; 23469015; 23478441; 23503662; 23563313; 23589227; 23589337; 23602568; 23604317; 23607312; 23658844; 23824909; 23868976; 23910095; 23951410; 24019069; 24035498; 24085301; 24157836; 24255178; 24318128; 24457600; 24469040 S-phase kinase-associated protein 1 HGNC:10899 HPRD:03255 MIM:601434 SKP1 Bin Zhao, Yue Liu, Oliver He DYT17 DYT18 DYT9 EIG12 GLUT GLUT1 GLUT1DS HTLVR PED WEB: http://www.ncbi.nlm.nih.gov/gene SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 6513 1p34.2 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001939 (EC: IEA); GO_0005355 (EC: TAS, PMID: 9462754); GO_0005515 (EC: IPI, PMID: 18347014); GO_0005886 (EC: TAS); GO_0005901 (EC: IEA); GO_0005911 (EC: IEA); GO_0005975 (EC: TAS); GO_0006112 (EC: TAS); GO_0006461 (EC: IDA, PMID: 18347014); GO_0006766 (EC: TAS); GO_0006767 (EC: TAS); GO_0006970 (EC: IEA); GO_0008645 (EC: TAS); GO_0015758 (EC: TAS); GO_0016020 (EC: TAS, PMID: 3028891); GO_0016021 (EC: IEA); GO_0016323 (EC: IEA); GO_0019852 (EC: TAS); GO_0019900 (EC: IEA); GO_0030496 (EC: IDA, PMID: 15166316); GO_0030864 (EC: IDA, PMID: 18347014); GO_0033300 (EC: IEA); GO_0042149 (EC: IEA); GO_0042470 (EC: IEA); GO_0042802 (EC: IPI, PMID: 1429721); GO_0042910 (EC: IEA); GO_0043621 (EC: IDA, PMID: 18347014); GO_0044281 (EC: TAS); GO_0050796 (EC: TAS); GO_0055056 (EC: IEA); GO_0055085 (EC: TAS); GO_0070062 (EC: IDA); GO_0072562 (EC: IDA) PMID: 1429721; 2394733; 2834252; 3028891; 3170580; 3839598; 7798206; 7829101; 8619474; 8662691; 8839927; 9110174; 9153243; 9462754; 10086067; 10198040; 10227690; 10562431; 10655495; 10759149; 10980529; 11007796; 11136715; 11168944; 11231353; 11296192; 11425315; 11477169; 11603379; 11681785; 11747430; 11774318; 11836704; 11842083; 11920478; 11953883; 11991658; 12064911; 12086959; 12112827; 12122099; 12133004; 12145475; 12379105; 12379106; 12477932; 12554125; 12583599; 12673735; 12752470; 12849991; 12942120; 12969152; 14622599; 14674124; 14679154; 14688257; 14702039; 14757434; 14991538; 15073187; 15086844; 15147968; 15166316; 15331928; 15342556; 15454279; 15489334; 15502921; 15682272; 15709778; 15745834; 15767416; 15778389; 15823019; 15847702; 15924676; 15955807; 15967114; 16125330; 16126902; 16136514; 16142350; 16147855; 16169070; 16172126; 16195374; 16220828; 16273245; 16310037; 16344560; 16407180; 16443776; 16519917; 16681687; 16681688; 16800634; 16842248; 17020877; 17064664; 17071132; 17080242; 17081065; 17167225; 17192790; 17294670; 17387384; 17404017; 17442736; 17451637; 17452775; 17504522; 17554865; 17591274; 17611657; 17635959; 17727838; 17854396; 17991316; 18097583; 18172662; 18177733; 18191496; 18212354; 18227718; 18245775; 18246802; 18271924; 18290322; 18311082; 18324916; 18343752; 18347014; 18351386; 18387950; 18401196; 18410529; 18422279; 18451999; 18565734; 18577546; 18613291; 18614966; 18676680; 18695903; 18726700; 18764953; 18821326; 18948400; 18953257; 18973239; 18981181; 18987250; 18990414; 19016655; 19020718; 19020742; 19085834; 19142800; 19152396; 19166280; 19170196; 19173807; 19234439; 19286567; 19289587; 19292042; 19303158; 19304421; 19347605; 19366592; 19386788; 19420105; 19434538; 19449892; 19465749; 19471022; 19490621; 19533082; 19533890; 19536037; 19554504; 19569052; 19587357; 19619276; 19625176; 19630075; 19648108; 19648882; 19655166; 19681047; 19692168; 19709351; 19738201; 19798636; 19819644; 19822956; 19883765; 19948975; 19955252; 20030103; 20063428; 20079187; 20113375; 20221955; 20301603; 20375117; 20382060; 20395120; 20424473; 20428049; 20512538; 20526721; 20527231; 20540786; 20569445; 20574033; 20607826; 20630673; 20679470; 20687207; 20703861; 20730618; 20803547; 20846124; 20854211; 20937822; 20947823; 20965718; 21029693; 21033220; 21075472; 21109935; 21135204; 21139048; 21194153; 21206329; 21252943; 21270293; 21273616; 21281236; 21294792; 21295279; 21306648; 21317389; 21321933; 21332301; 21343253; 21348951; 21384913; 21395180; 21411785; 21438910; 21442770; 21445818; 21475039; 21521642; 21528061; 21546213; 21555602; 21697701; 21707071; 21791420; 21808860; 21832227; 21838819; 21870331; 21899256; 21906983; 21920790; 21938742; 21962875; 21963094; 21986508; 21987572; 21987722; 22011817; 22029179; 22069254; 22072148; 22153830; 22199327; 22200795; 22221271; 22228332; 22234250; 22234467; 22253523; 22263435; 22270867; 22282454; 22282645; 22304920; 22308487; 22363641; 22376167; 22398711; 22437877; 22470192; 22475893; 22483234; 22509097; 22623428; 22663547; 22673619; 22704013; 22707195; 22795339; 22800355; 22812641; 22813791; 22814174; 22835601; 22843905; 22847606; 22888973; 22899793; 22901702; 22939629; 22961556; 22971162; 23000965; 23002041; 23030583; 23076555; 23098453; 23106342; 23108021; 23187830; 23219802; 23227892; 23280796; 23306390; 23359198; 23453806; 23480298; 23483445; 23615963; 23661345; 23720776; 23740044; 23744486; 23861325; 23935399; 24164300; 24343741 solute carrier family 2 (facilitated glucose transporter), member 1 Ensembl:ENSG00000117394 HGNC:11005 HPRD:00683 MIM:138140 Vega:OTTHUMG00000007657 SLC2A1 Bin Zhao, Yue Liu, Oliver He GLUT3 WEB: http://www.ncbi.nlm.nih.gov/gene SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 6515 12p13.3 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0005355 (EC: IEA); GO_0005886 (EC: TAS); GO_0005975 (EC: TAS); GO_0006766 (EC: TAS); GO_0006767 (EC: TAS); GO_0008645 (EC: TAS); GO_0015758 (EC: TAS); GO_0016021 (EC: IEA); GO_0019852 (EC: TAS); GO_0044281 (EC: TAS); GO_0055085 (EC: TAS); GO_0070062 (EC: IDA) PMID: 1417839; 1695905; 3170580; 7502272; 8457197; 9253355; 9477959; 10086067; 11991658; 12064911; 12112827; 12397394; 12477932; 12554125; 12583599; 14757434; 15123239; 15489334; 16049004; 16125330; 16136514; 16169070; 16303743; 17442736; 17559076; 17611657; 17920708; 18029348; 18172662; 18299470; 18401196; 18764953; 18802725; 18976975; 19261894; 19322201; 19536037; 19554504; 19659459; 19681047; 19782666; 19786962; 20308990; 20424473; 20428049; 20468064; 20599725; 20870738; 21890473; 21920790; 21963094; 21987572; 22000473; 22069254; 22113212; 22234467; 22265971; 22270867; 22645302; 22663547; 22706202; 22876317; 22901689; 22901702; 23341039; 23343953; 23720776; 23995067 solute carrier family 2 (facilitated glucose transporter), member 3 Ensembl:ENSG00000059804 HGNC:11007 HPRD:00686 MIM:138170 Vega:OTTHUMG00000133685 SLC2A3 Bin Zhao, Yue Liu, Oliver He GLUT4 WEB: http://www.ncbi.nlm.nih.gov/gene SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 6517 17p13 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0005355 (EC: TAS, PMID: 2649253); GO_0005515 (EC: IPI, PMID: 19478182); GO_0005771 (EC: IEA); GO_0005886 (EC: IDA, PMID: 12556481); GO_0005886 (EC: TAS); GO_0005887 (EC: IEA); GO_0005905 (EC: IEA); GO_0005975 (EC: TAS); GO_0008645 (EC: TAS); GO_0009897 (EC: IDA, PMID: 14562105); GO_0010021 (EC: IEA); GO_0012505 (EC: ISS); GO_0012506 (EC: IDA, PMID: 14562105); GO_0015758 (EC: TAS, PMID: 12556481); GO_0016020 (EC: TAS, PMID: 2649253); GO_0030136 (EC: IDA, PMID: 19478182); GO_0030140 (EC: IEA); GO_0032593 (EC: IDA, PMID: 19590752); GO_0032593 (EC: ISS); GO_0032869 (EC: IDA, PMID: 12556481); GO_0042383 (EC: IEA); GO_0042593 (EC: IDA, PMID: 14562105); GO_0044281 (EC: TAS); GO_0045471 (EC: IEA); GO_0046323 (EC: NAS, PMID: 11742412); GO_0048471 (EC: IDA, PMID: 12556481); GO_0050873 (EC: IEA); GO_0055056 (EC: IEA); GO_0055085 (EC: TAS); GO_0061024 (EC: TAS); GO_0070062 (EC: IEA); GO_0071470 (EC: IEA) PMID: 1397719; 1521731; 1601840; 1756912; 1918382; 2568955; 2649253; 2656669; 7916714; 8300557; 9388492; 10068455; 10606624; 10655495; 11003568; 11217863; 11500317; 11742412; 11842083; 11994746; 12064911; 12079888; 12145475; 12467732; 12477932; 12556481; 12565902; 12583599; 12606502; 12631717; 12700047; 12716391; 12716734; 14562105; 14630949; 14747278; 15166000; 15182197; 15184360; 15247266; 15292352; 15334390; 15480742; 15489334; 15528266; 15731326; 15864539; 15992544; 16096283; 16213228; 16396496; 16497797; 16497805; 16647043; 16763099; 16787385; 16803853; 16966355; 17003346; 17035674; 17164432; 17220298; 17382906; 17448565; 17496362; 17611657; 17717074; 18056982; 18067156; 18184930; 18249389; 18299470; 18635880; 18660489; 18676680; 18713752; 18769028; 18778861; 19035854; 19170196; 19188436; 19219452; 19251038; 19286271; 19321702; 19328476; 19375584; 19389739; 19478182; 19549745; 19554504; 19590752; 19625176; 19648108; 19692168; 19885647; 19913121; 19948975; 19955252; 20103707; 20173759; 20352120; 20363751; 20406953; 20417083; 20501875; 20625434; 20628086; 20854370; 20965718; 21147915; 21187969; 21454505; 21454690; 21454697; 21468601; 21547502; 21604201; 21606541; 21645024; 21668369; 21757715; 21796809; 21883150; 21986508; 22114711; 22286219; 22297303; 22384078; 22403297; 22452979; 22488520; 22496345; 22663547; 22673408; 22971162; 22992739; 23072821; 23202124; 23239154; 23424197; 23546602; 23746177; 23800880; 24216110 solute carrier family 2 (facilitated glucose transporter), member 4 Ensembl:ENSG00000181856 HGNC:11009 HPRD:00688 MIM:138190 Vega:OTTHUMG00000102181 SLC2A4 Bin Zhao, Yue Liu, Oliver He ISC1 NSMASE NSMASE1 WEB: http://www.ncbi.nlm.nih.gov/gene SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 6610 RP5-919F19.2 6q21 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0004767 (EC: IEA); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 9520418); GO_0005901 (EC: IEA); GO_0006665 (EC: TAS); GO_0006684 (EC: TAS, PMID: 9520418); GO_0006687 (EC: TAS); GO_0009612 (EC: IEA); GO_0044281 (EC: TAS); GO_0046513 (EC: IEA); GO_0046872 (EC: IEA); GO_0048011 (EC: TAS); GO_0097190 (EC: TAS) PMID: 8889548; 9520418; 10608884; 11238738; 11997500; 12477932; 12566438; 12676795; 14689449; 15013522; 15051724; 15175033; 15489334; 15509740; 16344560; 17207965; 17212982; 17272284; 17344303; 17449104; 18040843; 18391951; 19698806; 19817993; 19834535; 19913121; 20378749; 20448054; 20628086; 20836852; 21335555; 21906983; 22899568 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) Ensembl:ENSG00000135587 HGNC:11121 HPRD:04608 MIM:603498 Vega:OTTHUMG00000015348 SMPD2 Bin Zhao, Yue Liu, Oliver He NACP PARK1 PARK4 PD1 WEB: http://www.ncbi.nlm.nih.gov/gene SNCA synuclein, alpha (non A4 component of amyloid precursor) 6622 4q21 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0000287 (EC: IDA, PMID: 11850416); GO_0001774 (EC: IEA); GO_0001921 (EC: IDA, PMID: 18980610); GO_0001933 (EC: IEA); GO_0001956 (EC: IEA); GO_0005504 (EC: IDA, Qualifier: NOT, PMID: 16687662); GO_0005507 (EC: IDA); GO_0005509 (EC: IDA, PMID: 11312271); GO_0005515 (EC: IPI, PMID: 11943812); GO_0005543 (EC: IEA); GO_0005576 (EC: TAS); GO_0005634 (EC: IDA, PMID: 12406186); GO_0005640 (EC: IEA); GO_0005737 (EC: IDA, PMID: 12406186); GO_0005739 (EC: IEA); GO_0005791 (EC: IEA); GO_0005794 (EC: IEA); GO_0005829 (EC: IDA, PMID: 8248242); GO_0005840 (EC: IEA); GO_0005886 (EC: IDA, PMID: 12958153); GO_0005938 (EC: IDA, PMID: 19157893); GO_0006631 (EC: IEA); GO_0006638 (EC: IEA); GO_0006644 (EC: IEA); GO_0006919 (EC: IDA); GO_0007006 (EC: IEA); GO_0007568 (EC: IEA); GO_0008017 (EC: IEA); GO_0008021 (EC: IEA); GO_0008198 (EC: IDA, PMID: 11850416); GO_0008270 (EC: IDA, PMID: 11850416); GO_0008344 (EC: IEA); GO_0010040 (EC: IDA, PMID: 11850416); GO_0010517 (EC: IDA, PMID: 15641770); GO_0010642 (EC: IDA, PMID: 12239163); GO_0014048 (EC: IEA); GO_0014059 (EC: TAS); GO_0015629 (EC: IDA, PMID: 17408955); GO_0016234 (EC: IDA); GO_0016491 (EC: IDA); GO_0019894 (EC: IPI, PMID: 16176937); GO_0019904 (EC: IEA); GO_0030054 (EC: IEA); GO_0030424 (EC: IDA, PMID: 12958153); GO_0030426 (EC: IDA, PMID: 12958153); GO_0030544 (EC: IPI, PMID: 18975920); GO_0031092 (EC: IDA, Qualifier: colocalizes_with, PMID: 12239163); GO_0031115 (EC: IDA); GO_0031623 (EC: IDA, PMID: 18980610); GO_0031648 (EC: IDA); GO_0032026 (EC: IDA, PMID: 11850416); GO_0032410 (EC: IDA, PMID: 16882008); GO_0032496 (EC: IDA, PMID: 12406186); GO_0032769 (EC: IDA, PMID: 11943812); GO_0033138 (EC: ISS); GO_0034341 (EC: IDA, PMID: 19157893); GO_0034599 (EC: IEA); GO_0035067 (EC: IDA, PMID: 16959795); GO_0040012 (EC: IEA); GO_0042393 (EC: IDA, PMID: 16959795); GO_0042416 (EC: TAS); GO_0042493 (EC: IEA); GO_0042775 (EC: IEA); GO_0042802 (EC: IPI, PMID: 16330551); GO_0043014 (EC: IPI, PMID: 11698390); GO_0043027 (EC: IDA, PMID: 10818098); GO_0043030 (EC: IEA); GO_0043066 (EC: IMP, PMID: 10818098); GO_0043154 (EC: IMP, PMID: 10818098); GO_0043195 (EC: IEA); GO_0043205 (EC: IDA, PMID: 18346205); GO_0043206 (EC: TAS); GO_0043274 (EC: IEA); GO_0043524 (EC: IEA); GO_0044344 (EC: IEA); GO_0045502 (EC: IPI, PMID: 16176937); GO_0045807 (EC: IDA, PMID: 18980610); GO_0045920 (EC: IMP, PMID: 12239163); GO_0045963 (EC: IEA); GO_0047485 (EC: IEA); GO_0048148 (EC: IEA); GO_0048156 (EC: IDA, PMID: 17408955); GO_0048169 (EC: IEA); GO_0048471 (EC: IDA); GO_0048487 (EC: IEA); GO_0048488 (EC: ISS); GO_0050808 (EC: IEA); GO_0050812 (EC: IEA); GO_0051219 (EC: IDA); GO_0051281 (EC: IDA, PMID: 15641770); GO_0051583 (EC: TAS); GO_0051585 (EC: IDA, PMID: 12958153); GO_0051612 (EC: IDA, PMID: 16882008); GO_0051622 (EC: IDA, PMID: 17156375); GO_0055074 (EC: IDA, Qualifier: NOT, PMID: 12239163); GO_0055114 (EC: IDA); GO_0060079 (EC: IEA); GO_0060291 (EC: IEA); GO_0060732 (EC: IDA, PMID: 15641770); GO_0060961 (EC: IDA, Qualifier: NOT, PMID: 19146388); GO_0070495 (EC: IDA, PMID: 12239163); GO_0070555 (EC: IDA, PMID: 12406186); GO_0071280 (EC: IDA); GO_0071872 (EC: TAS); GO_0071902 (EC: IDA) PMID: 7558013; 7568089; 7601450; 7601479; 7802671; 8248242; 8895469; 9163350; 9197268; 9462735; 9750188; 10092675; 10319874; 10407019; 10417297; 10464279; 10506125; 10617630; 10764738; 10818098; 10852916; 10973942; 11078745; 11156617; 11162638; 11173882; 11207390; 11227130; 11261505; 11279280; 11292651; 11312271; 11331421; 11357958; 11376188; 11425308; 11438481; 11447312; 11472875; 11487204; 11502187; 11532993; 11588587; 11603807; 11683992; 11687285; 11698390; 11701929; 11724769; 11742726; 11744621; 11748744; 11751692; 11790792; 11812148; 11812782; 11813001; 11814343; 11814405; 11821392; 11823645; 11850416; 11852183; 11889756; 11893734; 11900526; 11943812; 11956199; 12025860; 12042811; 12044636; 12059041; 12062445; 12070658; 12084935; 12096713; 12115139; 12121974; 12122208; 12124613; 12138709; 12145295; 12151787; 12217698; 12220378; 12239163; 12351642; 12352614; 12358748; 12367530; 12377775; 12406186; 12428717; 12428728; 12477932; 12493604; 12534279; 12534296; 12541013; 12551928; 12558071; 12576551; 12586824; 12598733; 12610000; 12661766; 12670421; 12672538; 12672549; 12684441; 12695511; 12714745; 12716427; 12716914; 12722828; 12727333; 12752402; 12783249; 12784265; 12807436; 12807439; 12815044; 12815663; 12819014; 12857790; 12859192; 12859200; 12867415; 12868067; 12868068; 12885775; 12893833; 12900507; 12923179; 12923682; 12928483; 12958153; 12963044; 12973692; 14506232; 14507911; 14550771; 14572463; 14583385; 14593171; 14596606; 14627698; 14645218; 14657499; 14657500; 14690528; 14692700; 14699135; 14711827; 14742448; 14755719; 14756560; 14987449; 14996933; 14997013; 15028717; 15033366; 15050722; 15064394; 15078109; 15096050; 15099020; 15103328; 15109581; 15132984; 15135042; 15155902; 15159488; 15180968; 15207266; 15234109; 15236975; 15247485; 15265037; 15280438; 15282274; 15289452; 15300629; 15304594; 15317865; 15333840; 15338643; 15364911; 15365127; 15451224; 15451225; 15455394; 15459341; 15465356; 15489334; 15496679; 15498564; 15502868; 15502874; 15522241; 15522881; 15541000; 15542733; 15544803; 15556002; 15576511; 15590652; 15590933; 15591046; 15596612; 15615715; 15615727; 15622440; 15628875; 15628878; 15632170; 15641770; 15670652; 15671022; 15671169; 15671870; 15672325; 15673432; 15684072; 15685368; 15717024; 15718234; 15731118; 15732111; 15755676; 15765523; 15767574; 15791003; 15817478; 15840579; 15845543; 15852347; 15854772; 15863497; 15894486; 15895422; 15896322; 15904919; 15911350; 15917102; 15935068; 15935070; 15939304; 15941712; 15944382; 15955578; 15976091; 15978696; 15981014; 16020543; 16020550; 16037493; 16051265; 16081040; 16096643; 16110277; 16166095; 16176937; 16216085; 16227205; 16239214; 16242637; 16250025; 16269331; 16291942; 16297908; 16330147; 16330551; 16338184; 16344560; 16358335; 16365047; 16399671; 16403519; 16406146; 16410343; 16455667; 16464864; 16500997; 16516382; 16520971; 16524375; 16543523; 16567160; 16595633; 16604306; 16606366; 16606927; 16609851; 16611810; 16618118; 16651889; 16678164; 16679556; 16679557; 16687662; 16714300; 16752390; 16762368; 16780837; 16794039; 16806952; 16824047; 16847063; 16882008; 16896109; 16896314; 16930553; 16934409; 16947080; 16953580; 16959772; 16959793; 16959795; 16981712; 16997873; 17005870; 17010992; 17012252; 17012257; 17017516; 17017543; 17049244; 17055279; 17077307; 17078049; 17156375; 17156376; 17166628; 17174013; 17176082; 17199224; 17200685; 17209557; 17209570; 17222106; 17254569; 17291816; 17292657; 17309880; 17325715; 17335904; 17373725; 17374032; 17374033; 17374364; 17376994; 17387688; 17408955; 17451452; 17465029; 17489854; 17530780; 17531291; 17531952; 17554782; 17558898; 17573347; 17576801; 17603039; 17625105; 17635667; 17653558; 17675576; 17681534; 17683088; 17692832; 17706644; 17708336; 17712623; 17714183; 17785456; 17853477; 17868672; 17872362; 17873367; 17893145; 17904099; 17918232; 17955272; 17963364; 17982729; 17985233; 18000672; 18005258; 18018485; 18018486; 18031063; 18036154; 18039462; 18055555; 18061619; 18065497; 18070888; 18162487; 18162536; 18178617; 18179253; 18182484; 18182779; 18195004; 18195271; 18210157; 18211709; 18221373; 18245082; 18258594; 18261456; 18261982; 18282005; 18291704; 18295208; 18314273; 18322262; 18322396; 18322646; 18329380; 18331289; 18335262; 18343814; 18346205; 18362284; 18369446; 18382667; 18390556; 18393229; 18404644; 18413475; 18417705; 18423664; 18436529; 18436957; 18440504; 18449945; 18451726; 18463503; 18463504; 18485051; 18491043; 18492487; 18494470; 18505736; 18539297; 18541113; 18541383; 18562315; 18566453; 18568448; 18571778; 18606870; 18614564; 18617532; 18622040; 18625222; 18634833; 18650345; 18661559; 18676060; 18692132; 18702517; 18702696; 18704197; 18704525; 18708765; 18751989; 18769546; 18775438; 18824390; 18843496; 18848547; 18852445; 18852892; 18951507; 18955133; 18973254; 18973346; 18975920; 18980610; 18985386; 19002552; 19004816; 19018246; 19022350; 19027885; 19032594; 19047559; 19049426; 19070597; 19071095; 19074459; 19101068; 19115126; 19126542; 19135032; 19139307; 19141614; 19146388; 19151622; 19152986; 19157893; 19164293; 19167501; 19182805; 19183551; 19196539; 19198857; 19203374; 19205068; 19219857; 19220042; 19224617; 19224863; 19248830; 19261853; 19289119; 19291219; 19295143; 19328209; 19345692; 19356597; 19361478; 19369384; 19404653; 19405094; 19410557; 19412953; 19429025; 19444607; 19460374; 19460457; 19470380; 19475667; 19476547; 19498036; 19501571; 19507712; 19526103; 19526281; 19535993; 19540308; 19548659; 19549071; 19553474; 19562770; 19576176; 19576220; 19580781; 19596443; 19609719; 19630439; 19632874; 19645749; 19646423; 19651612; 19651786; 19653131; 19655784; 19680561; 19722699; 19747490; 19759002; 19762560; 19771175; 19816809; 19826908; 19833127; 19833540; 19834617; 19837084; 19845160; 19847913; 19855133; 19875982; 19878656; 19889641; 19890971; 19891973; 19892735; 19895818; 19900407; 19915575; 19915576; 20026050; 20029978; 20036828; 20041693; 20043104; 20070850; 20071342; 20074453; 20074637; 20077428; 20089532; 20098416; 20106983; 20114052; 20121219; 20132485; 20140223; 20148295; 20152114; 20169066; 20197038; 20226185; 20301402; 20334438; 20334701; 20371330; 20379614; 20381070; 20383623; 20392839; 20403393; 20409326; 20423081; 20423294; 20437598; 20445049; 20445061; 20448034; 20463956; 20478361; 20489724; 20506312; 20513365; 20524960; 20533263; 20534649; 20540950; 20540987; 20550572; 20554859; 20599975; 20604806; 20615443; 20629174; 20634198; 20640532; 20648655; 20664293; 20664530; 20668263; 20669025; 20685363; 20693280; 20696318; 20697047; 20697102; 20711177; 20725866; 20798282; 20805224; 20828147; 20842103; 20847452; 20849899; 20854101; 20855506; 20876215; 20876472; 20887775; 20887871; 20919750; 20945981; 20947801; 20959456; 20969957; 20977677; 21044603; 21044948; 21046180; 21054681; 21056999; 21058943; 21060011; 21084426; 21085664; 21103359; 21103907; 21108951; 21116546; 21117662; 21124796; 21127069; 21159074; 21162130; 21166675; 21167933; 21179192; 21212878; 21215793; 21235576; 21236518; 21238487; 21245015; 21245577; 21248740; 21249223; 21255620; 21256122; 21271299; 21272100; 21280130; 21289072; 21292315; 21296890; 21300904; 21304957; 21309955; 21310263; 21317042; 21319811; 21330368; 21330369; 21331461; 21338582; 21342025; 21358815; 21391235; 21412942; 21425343; 21439320; 21443877; 21445308; 21453448; 21461961; 21462277; 21466165; 21474915; 21488084; 21489994; 21491910; 21524999; 21527634; 21541339; 21565333; 21570984; 21593311; 21600984; 21601954; 21611169; 21613474; 21641618; 21652707; 21653695; 21656370; 21656851; 21658409; 21658411; 21672073; 21683963; 21684335; 21689664; 21693148; 21693152; 21699177; 21700325; 21714002; 21718702; 21720016; 21721555; 21736378; 21738487; 21742527; 21746851; 21756873; 21757905; 21767644; 21779395; 21782946; 21795682; 21798243; 21798244; 21813214; 21816655; 21819966; 21832049; 21832061; 21838671; 21841800; 21846727; 21848810; 21849493; 21853288; 21858077; 21863007; 21865317; 21880335; 21883224; 21900206; 21905118; 21936000; 21953452; 21953697; 21953863; 21985244; 21990355; 21993592; 21994367; 22001247; 22003392; 22009045; 22009151; 22025277; 22029383; 22039514; 22042430; 22045699; 22065755; 22067166; 22076805; 22079575; 22082318; 22090514; 22104010; 22119730; 22147697; 22153624; 22155643; 22163275; 22165993; 22166424; 22167382; 22178859; 22182688; 22207004; 22227187; 22243833; 22248692; 22262231; 22267729; 22275250; 22286107; 22291217; 22302797; 22314685; 22315227; 22315428; 22319455; 22326202; 22334684; 22349157; 22350713; 22357653; 22361813; 22367999; 22392151; 22399752; 22399753; 22407793; 22411133; 22425546; 22426402; 22436655; 22438815; 22445250; 22451204; 22453917; 22475625; 22503729; 22508282; 22508489; 22513881; 22533435; 22537068; 22549133; 22550057; 22552968; 22558453; 22560502; 22570709; 22573613; 22581044; 22591216; 22610785; 22615757; 22617348; 22619171; 22622968; 22647715; 22669510; 22694188; 22695112; 22701661; 22705949; 22735540; 22737239; 22764233; 22767608; 22771474; 22771809; 22776201; 22814000; 22819391; 22821666; 22836259; 22843682; 22850485; 22860160; 22863883; 22880029; 22912757; 22914317; 22923346; 22923347; 22923367; 22936307; 22939629; 22940885; 22941029; 22944910; 22948283; 22961477; 22981881; 22983916; 22986484; 22988096; 23000061; 23011138; 23013868; 23022913; 23028833; 23038403; 23039195; 23077033; 23077527; 23098910; 23100443; 23123341; 23129765; 23149132; 23153578; 23175842; 23180276; 23182315; 23183827; 23200460; 23201181; 23225002; 23225009; 23225525; 23244416; 23250862; 23252394; 23283657; 23284971; 23300640; 23300799; 23308173; 23313024; 23319586; 23328951; 23333298; 23334595; 23344955; 23349712; 23360753; 23361255; 23362176; 23365056; 23374072; 23374074; 23383169; 23384371; 23389286; 23392688; 23413261; 23426727; 23437071; 23452040; 23454347; 23454680; 23457458; 23458258; 23463005; 23466394; 23492776; 23499431; 23505409; 23507417; 23509976; 23509978; 23532841; 23534813; 23553480; 23562552; 23576548; 23580063; 23583776; 23587141; 23603399; 23603979; 23607785; 23609437; 23626796; 23630590; 23656991; 23661100; 23667637; 23669636; 23674386; 23674458; 23674490; 23703938; 23705016; 23737253; 23739956; 23744071; 23744550; 23796501; 23817832; 23820587; 23827677; 23831067; 23891486; 23900411; 23936403; 24005725; 24026176; 24047453; 24066883; 24070323; 24113654; 24191706; 24218576; 24315858; 24374342; 24381286; 24501346 synuclein, alpha (non A4 component of amyloid precursor) Ensembl:ENSG00000145335 HGNC:11138 HPRD:01227 MIM:163890 SNCA Bin Zhao, Yue Liu, Oliver He ALS ALS1 HEL-S-44 IPOA SOD hSod1 homodimer WEB: http://www.ncbi.nlm.nih.gov/gene SOD1 superoxide dismutase 1, soluble 6647 21q22.11 20140408 9606 21 protein-coding Official from a nomenclature committee GO_0000187 (EC: ISS); GO_0000303 (EC: IDA, PMID: 16790527); GO_0001541 (EC: ISS); GO_0001819 (EC: IDA, PMID: 15544046); GO_0001890 (EC: NAS, PMID: 12485882); GO_0001895 (EC: ISS); GO_0001975 (EC: IEA); GO_0002262 (EC: ISS); GO_0002576 (EC: TAS); GO_0004784 (EC: EXP); GO_0004784 (EC: IDA, PMID: 12551919); GO_0004784 (EC: TAS); GO_0005507 (EC: IDA, PMID: 17008312); GO_0005515 (EC: IPI, PMID: 16369483); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 7172448); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005739 (EC: IDA, PMID: 16790527); GO_0005758 (EC: TAS); GO_0005759 (EC: NAS, PMID: 17008312); GO_0005777 (EC: IDA, PMID: 1332049); GO_0005777 (EC: ISS); GO_0005829 (EC: IDA, PMID: 16790527); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, Qualifier: colocalizes_with, PMID: 17077646); GO_0006302 (EC: ISS); GO_0006309 (EC: ISS); GO_0006749 (EC: ISS); GO_0006801 (EC: IDA, PMID: 12551919); GO_0006801 (EC: ISS); GO_0006879 (EC: ISS); GO_0007283 (EC: ISS); GO_0007566 (EC: ISS); GO_0007566 (EC: NAS, PMID: 10920331); GO_0007569 (EC: IMP, PMID: 12871978); GO_0007596 (EC: TAS); GO_0007605 (EC: ISS); GO_0007626 (EC: ISS); GO_0008089 (EC: ISS); GO_0008090 (EC: ISS); GO_0008217 (EC: ISS); GO_0008270 (EC: IDA, PMID: 17381088); GO_0009408 (EC: ISS); GO_0010033 (EC: IDA, PMID: 12921788); GO_0019226 (EC: ISS); GO_0019430 (EC: IBA); GO_0019430 (EC: ISS); GO_0030168 (EC: TAS); GO_0030346 (EC: IDA, PMID: 17324120); GO_0031012 (EC: IDA, PMID: 9699963); GO_0031410 (EC: IDA, PMID: 17077646); GO_0031667 (EC: IEA); GO_0032287 (EC: ISS); GO_0032314 (EC: IDA, PMID: 18219391); GO_0032839 (EC: IDA, PMID: 17324120); GO_0032930 (EC: IDA, PMID: 18219391); GO_0033081 (EC: NAS, PMID: 16716898); GO_0040014 (EC: ISS); GO_0042493 (EC: ISS); GO_0042542 (EC: ISS); GO_0042554 (EC: IEA); GO_0042802 (EC: IPI); GO_0042803 (EC: NAS, PMID: 10837872); GO_0043025 (EC: IDA, PMID: 17324120); GO_0043065 (EC: IC, PMID: 16790527); GO_0043085 (EC: IDA, PMID: 17324120); GO_0043234 (EC: IDA, PMID: 17324120); GO_0043524 (EC: ISS); GO_0045471 (EC: ISS); GO_0045541 (EC: IDA, PMID: 15473258); GO_0045859 (EC: IDA, PMID: 16254550); GO_0046620 (EC: NAS, PMID: 16716898); GO_0046688 (EC: IEA); GO_0046716 (EC: ISS); GO_0048365 (EC: IDA, PMID: 18219391); GO_0048538 (EC: NAS, PMID: 16716898); GO_0048678 (EC: ISS); GO_0050665 (EC: IDA, PMID: 15544046); GO_0050665 (EC: ISS); GO_0051087 (EC: IPI, PMID: 9726962); GO_0051881 (EC: IMP, PMID: 16790527); GO_0060047 (EC: IDA, PMID: 9539776); GO_0060052 (EC: ISS); GO_0060087 (EC: ISS); GO_0060088 (EC: ISS); GO_0070062 (EC: IDA, PMID: 19056867); GO_0072593 (EC: IDA); GO_1902177 (EC: IMP, PMID: 12551919) PMID: 752535; 1332049; 1463506; 2853161; 3160582; 3680284; 3889846; 6096825; 6316150; 6457647; 6577438; 6770891; 7002610; 7172448; 7496169; 7501156; 7643359; 7647793; 7655468; 7655469; 7655471; 7700376; 7755363; 7795609; 7836951; 7870076; 7881433; 7887412; 7911198; 7951249; 7951252; 7980516; 7997024; 8004110; 8069312; 8105280; 8179602; 8298637; 8332197; 8351519; 8446170; 8528216; 8592323; 8682505; 8900247; 8907321; 8909456; 8938700; 8990014; 9101297; 9131652; 9453566; 9455977; 9539776; 9541385; 9699963; 9718300; 9726962; 9817920; 10329151; 10400992; 10430435; 10439968; 10677207; 10732812; 10735277; 10809943; 10830953; 10837872; 10889018; 10920331; 11006081; 11115513; 11220750; 11350569; 11369193; 11457725; 11513882; 11527942; 11535232; 11561030; 11675874; 11756571; 11771762; 11854284; 11854285; 11912919; 11930144; 11951178; 11996514; 12039658; 12050154; 12099681; 12126755; 12127151; 12138710; 12144846; 12145308; 12210393; 12213295; 12215228; 12218958; 12270693; 12356748; 12393885; 12402272; 12437574; 12441104; 12442272; 12447480; 12458194; 12475980; 12477932; 12480087; 12485882; 12502789; 12531528; 12551919; 12573532; 12590575; 12597246; 12606529; 12626552; 12644909; 12649272; 12659845; 12661766; 12665801; 12686560; 12710511; 12710516; 12718436; 12729761; 12732844; 12738898; 12753090; 12754496; 12774661; 12783432; 12787913; 12815046; 12818209; 12871577; 12871978; 12921788; 12963085; 12963370; 12968035; 12972170; 13129803; 13129804; 14506936; 14526083; 14568129; 14578853; 14596848; 14630798; 14684739; 14690536; 14711010; 14718574; 14734542; 14759637; 14970233; 14975589; 14978393; 14981234; 14988262; 15006704; 15016076; 15050430; 15050437; 15068249; 15109247; 15123612; 15166009; 15193434; 15198682; 15223067; 15223614; 15233914; 15258228; 15263088; 15288122; 15295091; 15304256; 15326189; 15338334; 15350647; 15358145; 15377661; 15379995; 15456787; 15465081; 15473258; 15474511; 15475574; 15485869; 15488469; 15489334; 15507437; 15522970; 15531919; 15544046; 15546588; 15576639; 15579468; 15623718; 15629867; 15634772; 15672551; 15691826; 15743779; 15753080; 15755678; 15758154; 15789135; 15799963; 15812313; 15816858; 15829169; 15829914; 15851752; 15869407; 15870505; 15909112; 15952740; 15961078; 15990193; 16000321; 16000635; 16009131; 16020530; 16036425; 16046140; 16046141; 16079151; 16084730; 16094314; 16105836; 16132821; 16191429; 16236267; 16254550; 16291742; 16291929; 16369483; 16406071; 16407238; 16423367; 16424062; 16435343; 16467073; 16525202; 16540901; 16567804; 16583143; 16584877; 16600249; 16636275; 16644738; 16674979; 16716898; 16716900; 16730180; 16741123; 16758302; 16780879; 16790527; 16792821; 16798882; 16847061; 16857362; 16868544; 16871233; 16877401; 16880213; 16895791; 16903849; 16920710; 16943203; 16945901; 16952453; 16963403; 16973244; 16989689; 17005595; 17008312; 17038899; 17056476; 17065353; 17077646; 17092942; 17097745; 17157186; 17157513; 17164329; 17166276; 17171548; 17255946; 17257622; 17272778; 17292357; 17299743; 17324120; 17328801; 17336361; 17368952; 17381088; 17394531; 17418947; 17420412; 17453632; 17453634; 17457363; 17463094; 17469116; 17483589; 17504823; 17512922; 17513298; 17548825; 17549011; 17549529; 17555556; 17573040; 17592131; 17602442; 17624778; 17634480; 17636119; 17636250; 17636481; 17646272; 17652584; 17664146; 17666395; 17667843; 17683122; 17683925; 17689501; 17715066; 17725983; 17786603; 17823119; 17888947; 17902702; 17903209; 17914031; 17925878; 17979159; 17987632; 17992192; 18006498; 18029348; 18033592; 18054242; 18055113; 18057069; 18081837; 18160848; 18191946; 18192269; 18211954; 18219391; 18233996; 18239850; 18243716; 18246065; 18268245; 18273717; 18282652; 18301754; 18305395; 18307039; 18316367; 18319614; 18334481; 18337461; 18384644; 18387669; 18393442; 18415766; 18423055; 18424447; 18428003; 18469020; 18476619; 18480265; 18485920; 18504130; 18515363; 18552350; 18559949; 18574763; 18579581; 18582155; 18586551; 18596033; 18608091; 18608106; 18617166; 18622615; 18624915; 18636124; 18651250; 18652897; 18666828; 18676680; 18683239; 18690666; 18703498; 18712292; 18715867; 18727868; 18761352; 18775420; 18790046; 18806750; 18808763; 18809582; 18826962; 18840448; 18930811; 18951903; 18971355; 19000626; 19011015; 19016244; 19016906; 19022905; 19041781; 19056867; 19060114; 19064571; 19077113; 19088126; 19091752; 19091790; 19109932; 19119597; 19124506; 19139308; 19156168; 19170196; 19171884; 19174508; 19176896; 19187267; 19191304; 19196430; 19201909; 19227972; 19228676; 19233858; 19252762; 19259395; 19266020; 19268528; 19293633; 19299510; 19325915; 19332692; 19335999; 19344917; 19363716; 19369197; 19379791; 19399611; 19399816; 19409565; 19416874; 19423521; 19423540; 19429011; 19442735; 19459941; 19477268; 19478559; 19482907; 19483195; 19488901; 19497878; 19505917; 19515016; 19524271; 19527700; 19560448; 19576169; 19596401; 19625176; 19635794; 19651777; 19654524; 19655787; 19656261; 19660548; 19661182; 19672969; 19685188; 19692168; 19703565; 19705749; 19714405; 19726402; 19741096; 19751676; 19779023; 19787204; 19800308; 19805546; 19805550; 19818514; 19828437; 19845829; 19878539; 19895330; 19902052; 19910193; 19913121; 19917371; 19922144; 19922450; 19949914; 19953340; 19965850; 20011081; 20023586; 20056743; 20075587; 20084016; 20094844; 20097285; 20097856; 20105444; 20108167; 20111867; 20127819; 20151445; 20154138; 20176600; 20177826; 20184519; 20184521; 20184893; 20189984; 20191117; 20195357; 20201926; 20202083; 20221404; 20223753; 20226522; 20237496; 20301623; 20303959; 20309572; 20346360; 20362497; 20385105; 20399857; 20406884; 20406964; 20410108; 20416077; 20438785; 20460269; 20460594; 20472325; 20477822; 20485444; 20498711; 20514411; 20515426; 20539010; 20553075; 20553085; 20562451; 20570967; 20573565; 20577002; 20595380; 20598578; 20602615; 20616033; 20628086; 20644736; 20648658; 20664914; 20682279; 20682985; 20709807; 20714737; 20797535; 20801718; 20808835; 20816908; 20837142; 20838240; 20851292; 20871097; 20872977; 20877624; 20931343; 20931825; 20933032; 20953194; 21056687; 21062492; 21073275; 21078175; 21083503; 21084099; 21098299; 21102999; 21120636; 21120952; 21139048; 21140194; 21145892; 21151573; 21153888; 21179281; 21185345; 21210247; 21226712; 21239495; 21252941; 21257910; 21287393; 21325350; 21346313; 21354101; 21388680; 21396374; 21403029; 21413851; 21421868; 21469165; 21493711; 21506602; 21515558; 21549128; 21549454; 21550164; 21554318; 21574856; 21600285; 21605634; 21620832; 21624464; 21651514; 21655264; 21692800; 21700707; 21700728; 21733494; 21760539; 21780215; 21796667; 21800301; 21816178; 21825243; 21832997; 21839474; 21843597; 21877919; 21887272; 21890473; 21896300; 21908873; 21921984; 21930207; 21930926; 21940617; 21943126; 21963083; 21963094; 21969586; 21976959; 21986594; 22005552; 22023190; 22036626; 22049684; 22053931; 22072713; 22081209; 22088212; 22089180; 22094223; 22116045; 22117694; 22171159; 22185396; 22203790; 22210350; 22212531; 22214312; 22219285; 22249462; 22264771; 22292843; 22292847; 22320662; 22332887; 22343163; 22357533; 22390177; 22409359; 22416121; 22424128; 22431618; 22438926; 22448134; 22471903; 22475618; 22492046; 22493728; 22542526; 22542539; 22561328; 22580443; 22589106; 22590985; 22595939; 22595972; 22608880; 22609817; 22613021; 22647583; 22650006; 22651090; 22670878; 22735487; 22761419; 22768276; 22797053; 22804629; 22867017; 22869735; 22899264; 22910911; 22931816; 22939629; 22958044; 22967507; 22970972; 22972774; 22984565; 22987392; 22999954; 23000965; 23026746; 23030347; 23040663; 23076148; 23076707; 23114721; 23118898; 23147108; 23147503; 23147550; 23178947; 23182243; 23264618; 23286750; 23289810; 23291526; 23297859; 23298163; 23303748; 23332757; 23339308; 23414135; 23418589; 23431152; 23431167; 23455544; 23486940; 23496883; 23578819; 23580651; 23583391; 23592792; 23597337; 23612299; 23665075; 23720777; 23744890; 23760509; 23765103; 23781106; 23784844; 23792044; 23828685; 23831581; 23837654; 23853506; 23861388; 23911407; 23919400; 23927036; 24023695; 24032979; 24038157; 24065725; 24076220; 24140062; 24184207; 24292713; 24344300; 24501372 superoxide dismutase 1, soluble Ensembl:ENSG00000142168 HGNC:11179 HPRD:00937 MIM:147450 Vega:OTTHUMG00000084878 SOD1 Bin Zhao, Yue Liu, Oliver He C11orf32 LR11 LRP9 SORLA SorLA-1 gp250 WEB: http://www.ncbi.nlm.nih.gov/gene SORL1 sortilin-related receptor, L(DLR class) A repeats containing 6653 11q23.2-q24.2 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0004888 (EC: TAS, PMID: 9157966); GO_0005515 (EC: IPI, PMID: 14764453); GO_0005615 (EC: IDA, PMID: 14764453); GO_0005768 (EC: IDA, PMID: 16174740); GO_0005771 (EC: IEA); GO_0005794 (EC: IDA, PMID: 16174740); GO_0005887 (EC: TAS, PMID: 9157966); GO_0006605 (EC: IMP, PMID: 16174740); GO_0006869 (EC: IEA); GO_0006898 (EC: TAS, PMID: 9157966); GO_0007165 (EC: TAS, PMID: 9157966); GO_0008203 (EC: IEA); GO_0008219 (EC: IEA); GO_0008283 (EC: IEA); GO_0014910 (EC: IDA, PMID: 14764453); GO_0016020 (EC: IDA, PMID: 14764453); GO_0016477 (EC: IEA); GO_0030169 (EC: IPI, PMID: 17326667); GO_0034362 (EC: IEA); GO_0043025 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 8619474; 8940146; 9157966; 10375696; 11294867; 11557679; 11821067; 12477932; 12530537; 12970790; 14702039; 14764453; 15313836; 16174740; 16344560; 16407538; 16489755; 16531402; 16565469; 17110338; 17220890; 17326667; 17420311; 17589324; 17721864; 17826910; 17949987; 17975299; 17978276; 18063222; 18090307; 18093545; 18407551; 18541377; 18562096; 18603531; 18685254; 18713574; 18830724; 18938222; 19056867; 19064752; 19077115; 19364927; 19368828; 19539718; 19584446; 19653016; 19822782; 19889229; 19889475; 19913121; 20015111; 20047743; 20301340; 20379614; 20413850; 20534741; 20574532; 20625269; 20628086; 20634593; 20667857; 20689279; 20838585; 20880607; 20946940; 20970138; 21145461; 21147781; 21185108; 21206043; 21220680; 21385844; 21730226; 21989385; 21994944; 21997402; 22044026; 22127416; 22268729; 22279231; 22286501; 22297619; 22321011; 22472873; 22621900; 22750733; 22836009; 22927900; 22996644; 23127357; 23455993; 23463934; 23486467; 23525328; 23565137; 23602568; 23813966; 24001769 sortilin-related receptor, L(DLR class) A repeats containing Alzpathway: APP-SORL1 association. Source: https://pubmed.ncbi.nlm.nih.gov/16174740/ Ensembl:ENSG00000137642 HGNC:11185 HPRD:03595 MIM:602005 Vega:OTTHUMG00000166057 SORL1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene SOS2 son of sevenless homolog 2 (Drosophila) 6655 14q21 20140408 9606 14 protein-coding Official from a nomenclature committee GO_0003677 (EC: IEA); GO_0005089 (EC: IEA); GO_0005515 (EC: IPI, PMID: 14679214); GO_0005829 (EC: TAS); GO_0007264 (EC: TAS); GO_0007411 (EC: TAS); GO_0043065 (EC: TAS); GO_0046982 (EC: IEA); GO_0048011 (EC: TAS); GO_0051056 (EC: TAS); GO_0051057 (EC: IEA); GO_0097190 (EC: TAS) PMID: 7629138; 8276400; 8493579; 8943292; 9067577; 9182529; 9372945; 10675333; 10820259; 10938118; 10940929; 11003655; 11756498; 12097864; 12376548; 12477932; 12628188; 12787561; 14551139; 14679214; 15173068; 17143285; 17440948; 17474147; 18271526; 19289468; 19380743; 19531499; 19911011; 20467438; 20618341; 20697350; 20936779; 21706016; 21988832; 22558309; 23761422; 23956138; 24250222 son of sevenless homolog 2 (Drosophila) SOS2 Bin Zhao, Yue Liu, Oliver He AGX AGX1 AGX2 SPAG2 WEB: http://www.ncbi.nlm.nih.gov/gene UAP1 UDP-N-acteylglucosamine pyrophosphorylase 1 6675 1q23.3 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0003977 (EC: TAS); GO_0005829 (EC: TAS); GO_0006048 (EC: IEA); GO_0006048 (EC: TAS); GO_0006488 (EC: TAS); GO_0018279 (EC: TAS); GO_0030246 (EC: IEA); GO_0043687 (EC: TAS); GO_0044267 (EC: TAS) PMID: 8025165; 9603950; 9621304; 9765219; 11707391; 12477932; 15489334; 16710414; 16712791; 18029348; 18976975; 19322201; 19536175; 21139048; 21757351; 21890473; 21906983; 22939629; 23000965 UDP-N-acteylglucosamine pyrophosphorylase 1 Ensembl:ENSG00000117143 HGNC:12457 HPRD:04178 MIM:602862 Vega:OTTHUMG00000034419 UAP1 Bin Zhao, Yue Liu, Oliver He ASV SRC1 c-SRC p60-Src WEB: http://www.ncbi.nlm.nih.gov/gene SRC v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog 6714 RP5-823N20.1 20q12-q13 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0004672 (EC: IDA, PMID: 18616680); GO_0004672 (EC: TAS); GO_0004713 (EC: EXP); GO_0004713 (EC: IDA, PMID: 16441665); GO_0004713 (EC: TAS); GO_0004715 (EC: TAS, PMID: 19267251); GO_0005070 (EC: TAS, PMID: 9020193); GO_0005102 (EC: IPI, PMID: 19332538); GO_0005178 (EC: TAS, PMID: 19267251); GO_0005515 (EC: IPI, PMID: 10521452); GO_0005524 (EC: IEA); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA); GO_0005739 (EC: IDA, PMID: 19767770); GO_0005743 (EC: IDA, PMID: 12615910); GO_0005764 (EC: IDA); GO_0005770 (EC: IDA); GO_0005829 (EC: IDA, PMID: 19767770); GO_0005829 (EC: TAS); GO_0005856 (EC: IEA); GO_0005886 (EC: IDA); GO_0005886 (EC: TAS); GO_0005901 (EC: IDA, PMID: 17848177); GO_0007049 (EC: IEA); GO_0007155 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10734107); GO_0007172 (EC: TAS, PMID: 9924018); GO_0007173 (EC: TAS); GO_0007265 (EC: TAS); GO_0007411 (EC: TAS); GO_0007596 (EC: TAS); GO_0008543 (EC: TAS); GO_0016032 (EC: IEA); GO_0016301 (EC: TAS); GO_0018108 (EC: IDA); GO_0020037 (EC: IDA); GO_0030168 (EC: TAS); GO_0030900 (EC: IEA); GO_0031295 (EC: TAS); GO_0032463 (EC: IMP, PMID: 19767770); GO_0033146 (EC: IEA); GO_0033625 (EC: TAS, PMID: 19267251); GO_0035556 (EC: IDA, PMID: 15248232); GO_0038096 (EC: TAS); GO_0042169 (EC: IPI, PMID: 8070403); GO_0042802 (EC: IEA); GO_0043066 (EC: IMP, PMID: 19767770); GO_0043114 (EC: TAS, PMID: 19267251); GO_0043154 (EC: IMP, PMID: 19767770); GO_0043393 (EC: IEA); GO_0044325 (EC: IPI, PMID: 12538589); GO_0045087 (EC: TAS); GO_0045124 (EC: TAS, PMID: 19267251); GO_0045453 (EC: ISS); GO_0046777 (EC: IDA, PMID: 16441665); GO_0046875 (EC: IPI, PMID: 12925710); GO_0048011 (EC: TAS); GO_0048477 (EC: IEA); GO_0050847 (EC: ISS); GO_0050900 (EC: TAS); GO_0051219 (EC: IPI, PMID: 16441665); GO_0051895 (EC: ISS); GO_0051897 (EC: IMP, PMID: 19767770); GO_0051902 (EC: IMP, PMID: 19767770); GO_0060065 (EC: IEA); GO_0060444 (EC: IEA); GO_0061024 (EC: TAS); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070374 (EC: IEA); GO_0070555 (EC: IMP, PMID: 19281832); GO_0070851 (EC: IPI, PMID: 16479011); GO_0071393 (EC: ISS); GO_0071803 (EC: IEA); GO_0090263 (EC: IEA); GO_2000811 (EC: IMP); GO_2001237 (EC: IMP, PMID: 19767770); GO_2001243 (EC: IMP, PMID: 19767770) PMID: 1310678; 1374686; 1379745; 1383690; 1384654; 1545818; 1689310; 1691439; 1713455; 1717825; 2173144; 2457390; 2506951; 2581127; 2582238; 2681803; 2981336; 2996754; 2996780; 3299057; 3917576; 6092965; 6304688; 6333425; 7510703; 7513017; 7513429; 7515480; 7516469; 7517401; 7518772; 7519780; 7521304; 7527558; 7529876; 7530249; 7532003; 7534286; 7537265; 7537362; 7537495; 7539106; 7542762; 7678701; 7681396; 7682059; 7683128; 7691597; 7782294; 7997267; 8054685; 8070403; 8253717; 8272872; 8510939; 8621384; 8626374; 8632005; 8635998; 8647432; 8647855; 8657103; 8657134; 8681387; 8702721; 8761480; 8766817; 8797825; 8805332; 8810341; 8816475; 8824280; 8845374; 8849729; 8876196; 8878483; 8885868; 8900189; 8910575; 8918464; 8939605; 8940173; 8941336; 8953041; 8978822; 9012831; 9016807; 9020193; 9024657; 9028946; 9096689; 9118959; 9148935; 9169421; 9174343; 9178760; 9182531; 9195899; 9208935; 9223281; 9237663; 9261115; 9278444; 9297626; 9344858; 9388490; 9389695; 9507031; 9519902; 9560226; 9566874; 9584165; 9600099; 9621077; 9632142; 9655255; 9687503; 9687533; 9701558; 9710204; 9748248; 9763511; 9778343; 9786846; 9792645; 9819391; 9819392; 9822703; 9837922; 9837958; 9843378; 9867848; 9880482; 9924018; 9988270; 10022920; 10070972; 10075741; 10085298; 10092678; 10187839; 10195142; 10205168; 10206955; 10339567; 10358079; 10362724; 10391903; 10395945; 10428862; 10454579; 10455176; 10455194; 10458595; 10462375; 10467411; 10482988; 10487518; 10517671; 10521452; 10527887; 10544291; 10567404; 10571082; 10635328; 10636929; 10644995; 10657632; 10681522; 10688651; 10698938; 10734107; 10739664; 10744074; 10777539; 10777553; 10781592; 10787408; 10801826; 10829062; 10838070; 10846184; 10847592; 10858437; 10871840; 10884433; 10899172; 10918587; 10931187; 10935545; 10945997; 10959835; 10962563; 10971656; 10973497; 10978326; 10982829; 11007774; 11013076; 11013230; 11024032; 11031247; 11032808; 11039464; 11071635; 11078745; 11084024; 11085988; 11106497; 11113628; 11124251; 11127814; 11149959; 11152665; 11158331; 11278415; 11279024; 11279199; 11279201; 11294897; 11309200; 11313464; 11350938; 11353545; 11373296; 11375989; 11379820; 11382764; 11389730; 11431473; 11445557; 11481331; 11483589; 11483655; 11494128; 11514593; 11514617; 11520933; 11524430; 11564893; 11576548; 11577104; 11593413; 11602604; 11696545; 11708798; 11713277; 11723131; 11724572; 11739737; 11741599; 11741929; 11751924; 11780052; 11781820; 11827972; 11834516; 11834728; 11854294; 11872746; 11875070; 11877451; 11884411; 11896602; 11923305; 11927607; 11934669; 11934902; 11940572; 11940607; 11960376; 11964172; 11971983; 11980671; 11983694; 11994282; 11994743; 12011079; 12014986; 12024042; 12048194; 12052863; 12060669; 12063167; 12072427; 12091389; 12095943; 12138090; 12145209; 12153558; 12162444; 12163133; 12210743; 12215529; 12216109; 12219031; 12226752; 12235291; 12244095; 12387730; 12387813; 12393736; 12397603; 12402152; 12416028; 12420216; 12429742; 12429743; 12429837; 12444928; 12454018; 12456372; 12456510; 12462387; 12468645; 12473651; 12477932; 12482968; 12493773; 12506110; 12522270; 12538589; 12540842; 12540962; 12554790; 12558988; 12576423; 12588871; 12604776; 12606547; 12612073; 12612084; 12615910; 12615911; 12615930; 12618767; 12621061; 12624098; 12626508; 12630920; 12631284; 12637538; 12640114; 12645577; 12649275; 12650714; 12663375; 12695509; 12697812; 12707358; 12730241; 12734410; 12736255; 12753909; 12771149; 12789267; 12795607; 12796488; 12808100; 12810717; 12819203; 12829810; 12842760; 12846735; 12871937; 12878163; 12893822; 12893833; 12893883; 12907686; 12907754; 12925710; 12932824; 12933816; 12939401; 12941616; 12947321; 12972425; 12975382; 14504278; 14506255; 14517306; 14523024; 14551213; 14562045; 14617636; 14627343; 14661060; 14670955; 14676843; 14687660; 14688263; 14702039; 14706618; 14707140; 14739293; 14761972; 14766010; 14766744; 14963038; 14963108; 14978237; 14985122; 14985366; 14993658; 15001550; 15020686; 15027889; 15033452; 15060621; 15062102; 15062576; 15069201; 15070730; 15075377; 15078178; 15094065; 15116119; 15117969; 15122338; 15135048; 15140878; 15143158; 15175272; 15184363; 15190072; 15229287; 15248232; 15254245; 15271991; 15272013; 15276210; 15282304; 15286700; 15297464; 15304482; 15313931; 15337529; 15342783; 15363460; 15456896; 15466214; 15467744; 15485865; 15489334; 15494217; 15498833; 15522235; 15522237; 15528270; 15532711; 15546918; 15546919; 15557335; 15564375; 15574420; 15583006; 15588985; 15601848; 15604093; 15618223; 15623523; 15623525; 15637072; 15638726; 15647376; 15688032; 15689620; 15695802; 15696169; 15707590; 15735682; 15746183; 15749833; 15774483; 15777850; 15782139; 15782160; 15784253; 15788656; 15791211; 15818752; 15834155; 15835917; 15845350; 15851033; 15853660; 15872086; 15872089; 15919723; 15923603; 15937332; 15939018; 16002533; 16002577; 16005629; 16020549; 16027153; 16051665; 16055703; 16103119; 16105876; 16116474; 16139795; 16158055; 16158247; 16163059; 16166096; 16168436; 16169070; 16186108; 16260653; 16273093; 16291744; 16317091; 16322069; 16371650; 16374509; 16377083; 16400523; 16407214; 16412380; 16414009; 16423881; 16432186; 16434701; 16440311; 16441665; 16465417; 16479011; 16492668; 16523241; 16532030; 16537602; 16543952; 16569657; 16581250; 16609991; 16619028; 16636290; 16636672; 16640565; 16690617; 16728403; 16825188; 16837460; 16844778; 16849330; 16860316; 16862215; 16882656; 16891307; 16894533; 16899217; 16923966; 16930961; 16951177; 16957778; 16959222; 16964398; 16966330; 16990796; 17018524; 17030621; 17038311; 17038317; 17046078; 17056000; 17062641; 17088251; 17094785; 17097642; 17129785; 17135298; 17141222; 17158602; 17170700; 17192257; 17215324; 17224200; 17254967; 17284441; 17307333; 17317726; 17325034; 17363140; 17369846; 17400812; 17412687; 17443665; 17471235; 17474147; 17502350; 17510314; 17525734; 17537434; 17537435; 17553930; 17574549; 17593353; 17620427; 17627277; 17630833; 17631495; 17641225; 17641689; 17691821; 17699109; 17716980; 17785434; 17785844; 17803936; 17804738; 17848177; 17849451; 17855352; 17868192; 17875712; 17933561; 17934522; 17936276; 17967179; 17974954; 17997837; 18005680; 18024423; 18042718; 18057010; 18061419; 18063684; 18067320; 18069897; 18070925; 18080320; 18086662; 18089800; 18095097; 18156174; 18160712; 18180305; 18194650; 18209475; 18211905; 18223692; 18251740; 18252715; 18296443; 18296648; 18322799; 18327819; 18328427; 18353785; 18388244; 18397177; 18403635; 18434302; 18441016; 18443354; 18445593; 18451158; 18451880; 18457834; 18463161; 18467332; 18474606; 18493848; 18503159; 18509267; 18524994; 18550772; 18562041; 18566211; 18594011; 18594017; 18596232; 18606683; 18616680; 18617000; 18620005; 18632638; 18644869; 18662984; 18667434; 18694941; 18713744; 18802114; 18832467; 18839319; 18922903; 18924149; 18948751; 19035465; 19047046; 19048118; 19050761; 19056867; 19066724; 19074832; 19111446; 19112177; 19130504; 19144635; 19147496; 19160018; 19176482; 19199380; 19202075; 19223541; 19258394; 19262138; 19262695; 19265199; 19267251; 19281832; 19302982; 19305428; 19321744; 19329556; 19332538; 19380485; 19393585; 19419966; 19435802; 19435911; 19447874; 19453261; 19457864; 19479902; 19481075; 19487280; 19497848; 19515834; 19535918; 19540193; 19546854; 19620276; 19665017; 19690143; 19703310; 19711372; 19718473; 19730683; 19755386; 19762712; 19767770; 19769962; 19789182; 19802004; 19807924; 19808905; 19822667; 19833732; 19840943; 19843640; 19852943; 19861161; 19861436; 19875457; 19878981; 19881549; 19887442; 19891780; 19892015; 19903481; 19924282; 19940159; 19948031; 19948721; 19956670; 19965650; 20013033; 20028973; 20053757; 20056178; 20100835; 20127031; 20152043; 20155281; 20176789; 20332114; 20333651; 20338915; 20351107; 20353998; 20371672; 20371703; 20378826; 20379791; 20388777; 20400511; 20405349; 20431421; 20439986; 20448061; 20452982; 20460377; 20525694; 20534535; 20540746; 20584982; 20615878; 20659428; 20661303; 20705589; 20796316; 20829350; 20871631; 20929444; 20936779; 20943948; 20956943; 20959018; 21036157; 21045155; 21052789; 21056984; 21058027; 21062671; 21062896; 21075308; 21139048; 21151980; 21156787; 21169408; 21177802; 21195420; 21225226; 21248042; 21257711; 21268077; 21273440; 21278788; 21281808; 21291860; 21300758; 21301049; 21309750; 21335603; 21343398; 21383697; 21390316; 21419342; 21445358; 21445970; 21490376; 21490433; 21496277; 21496428; 21508333; 21509526; 21536681; 21541295; 21573184; 21613217; 21618517; 21632985; 21637765; 21646863; 21681336; 21685945; 21701559; 21703394; 21710320; 21716326; 21725161; 21725282; 21725358; 21737505; 21741415; 21757638; 21757754; 21798038; 21840312; 21855630; 21856747; 21859709; 21875461; 21890473; 21892329; 21900206; 21911421; 21917910; 21953458; 21961241; 21984372; 21994334; 21994943; 22037769; 22052839; 22105363; 22110760; 22134837; 22200682; 22203239; 22203672; 22238675; 22241990; 22247553; 22252554; 22279592; 22310287; 22315411; 22321370; 22323579; 22328516; 22353809; 22354875; 22361730; 22362758; 22364282; 22378042; 22383989; 22388352; 22393415; 22402981; 22414081; 22422068; 22447928; 22479394; 22488171; 22508042; 22532564; 22577141; 22577255; 22586492; 22591684; 22653778; 22658320; 22660634; 22675553; 22689581; 22716210; 22745667; 22760497; 22768099; 22810232; 22833562; 22865929; 22880054; 22888118; 22927910; 22957061; 22957062; 22974441; 23066026; 23119029; 23175185; 23178654; 23179791; 23209645; 23242808; 23271399; 23277333; 23281368; 23291984; 23292187; 23333852; 23338526; 23341451; 23349873; 23360994; 23380740; 23393555; 23400779; 23497302; 23500080; 23532252; 23536784; 23562843; 23563312; 23585863; 23615537; 23640056; 23651497; 23696930; 23703528; 23707526; 23726918; 23751956; 23790975; 23804646; 23873931; 23882690; 23913825; 23920124; 23940647; 23949219; 24037722; 24100030; 24108181; 24120917; 24123009; 24136222; 24151076; 24183378; 24239173; 24250222; 24369899 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog Ensembl:ENSG00000197122 HGNC:11283 HPRD:01819 MIM:190090 Vega:OTTHUMG00000032417 SRC Bin Zhao, Yue Liu, Oliver He CP-22 CP22 SCN V19 WEB: http://www.ncbi.nlm.nih.gov/gene SRI sorcin 6717 7q21.1 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0001508 (EC: TAS, PMID: 9668070); GO_0002020 (EC: IPI, PMID: 10748169); GO_0004198 (EC: IBA); GO_0005102 (EC: TAS, PMID: 9668070); GO_0005246 (EC: TAS, PMID: 9668070); GO_0005509 (EC: IDA, PMID: 17215369); GO_0005515 (EC: IPI); GO_0005737 (EC: TAS, PMID: 16130169); GO_0005789 (EC: IDA, PMID: 10672515); GO_0005829 (EC: IDA, PMID: 10748169); GO_0006508 (EC: IBA); GO_0006810 (EC: TAS, PMID: 9668070); GO_0006816 (EC: IEA); GO_0006880 (EC: TAS, PMID: 9668070); GO_0006942 (EC: TAS, PMID: 9668070); GO_0007165 (EC: TAS, PMID: 16130169); GO_0007507 (EC: TAS, PMID: 9668070); GO_0007517 (EC: TAS, PMID: 9668070); GO_0008016 (EC: TAS, PMID: 9668070); GO_0010459 (EC: IMP, PMID: 12754254); GO_0010649 (EC: TAS, PMID: 17699613); GO_0010880 (EC: TAS, PMID: 17699613); GO_0016020 (EC: IDA, PMID: 10748169); GO_0016529 (EC: TAS, PMID: 17699613); GO_0030018 (EC: IDA, PMID: 12754254); GO_0030315 (EC: TAS, PMID: 17699613); GO_0033017 (EC: IEA); GO_0035774 (EC: IEA); GO_0042584 (EC: IDA, Qualifier: colocalizes_with, PMID: 9268363); GO_0042994 (EC: IEA); GO_0044325 (EC: TAS, PMID: 12754254); GO_0046982 (EC: IPI, PMID: 12804766); GO_0051281 (EC: IEA); GO_0051924 (EC: IMP, PMID: 12754254); GO_0060315 (EC: IDA, PMID: 17699613); GO_0070062 (EC: IDA, PMID: 15326289); GO_0070491 (EC: IEA); GO_0086004 (EC: IMP, PMID: 12754254); GO_1901077 (EC: IMP, PMID: 12754254); GO_1901841 (EC: IMP, PMID: 12754254); GO_1901844 (EC: IMP, PMID: 17130302); GO_2000678 (EC: IEA) PMID: 1286667; 2901906; 7592856; 7835417; 7873602; 8561500; 9268363; 9570944; 9668070; 10672515; 10748169; 11714909; 12408767; 12411058; 12477932; 12754254; 12804766; 15231748; 15326289; 15489334; 15808837; 15862967; 16130169; 16169070; 16189514; 16320026; 16341674; 16344560; 16931553; 16934756; 17130302; 17215369; 17541155; 17643375; 17699613; 17893145; 18315902; 18423116; 18624398; 19738201; 19885748; 19913121; 20012234; 20628086; 20647321; 20858460; 20972266; 21109982; 21139048; 21890473; 21906983; 21963094; 21979464; 21988832; 22052463; 22053931; 22338092; 22623428; 22701893; 23000965; 23602568 sorcin Ensembl:ENSG00000075142 HGNC:11292 HPRD:01680 MIM:182520 Vega:OTTHUMG00000157267 SRI Bin Zhao, Yue Liu, Oliver He SMST WEB: http://www.ncbi.nlm.nih.gov/gene SST somatostatin 6750 3q28 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0005179 (EC: TAS, PMID: 9886848); GO_0005576 (EC: TAS); GO_0005615 (EC: TAS, PMID: 9437026); GO_0006972 (EC: IEA); GO_0007166 (EC: TAS, PMID: 9437026); GO_0007186 (EC: TAS, PMID: 8405411); GO_0007267 (EC: TAS, PMID: 6145156); GO_0007268 (EC: TAS, PMID: 9437026); GO_0007584 (EC: TAS, PMID: 6145156); GO_0007586 (EC: TAS, PMID: 6145156); GO_0008285 (EC: TAS, PMID: 9886848); GO_0008628 (EC: TAS, PMID: 8961277); GO_0009408 (EC: IEA); GO_0030334 (EC: IEA); GO_0042493 (EC: IEA); GO_0043025 (EC: IEA); GO_0043200 (EC: IEA); GO_0048545 (EC: IEA) PMID: 1337145; 1346068; 4682131; 6126875; 6142531; 6145156; 6196780; 7908405; 8100352; 8405411; 8612489; 8961277; 9437026; 9878821; 9886848; 11753230; 11814357; 11823046; 11860030; 11920268; 12174892; 12477932; 12684217; 12902325; 12952361; 14559725; 15266779; 15286801; 15358539; 15472172; 15489334; 15590633; 15655830; 16043736; 16211223; 16214911; 16284732; 16456666; 16606630; 16736556; 16764985; 16804989; 16952549; 17130427; 17229384; 17327350; 17704349; 17987251; 18196269; 18240029; 18310290; 18473402; 18567806; 18577758; 18617261; 18753129; 19086053; 19106227; 19328558; 19423539; 19559700; 19607727; 19733630; 20043075; 20055772; 20501436; 20602615; 20629740; 20634197; 20734064; 20800603; 20810604; 20819778; 21232602; 21368047; 21632809; 21640760; 22366760; 22509294; 22528496; 22532184; 22932785; 23128854; 23312523; 23825418 somatostatin Ensembl:ENSG00000157005 HGNC:11329 HPRD:08920 MIM:182450 Vega:OTTHUMG00000156462 SST Bin Zhao, Yue Liu, Oliver He LKB1 PJS hLKB1 WEB: http://www.ncbi.nlm.nih.gov/gene STK11 serine/threonine kinase 11 6794 19p13.3 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000287 (EC: IDA, PMID: 12805220); GO_0001558 (EC: ISS); GO_0001894 (EC: IEA); GO_0001944 (EC: ISS); GO_0002039 (EC: IDA, PMID: 11430832); GO_0004674 (EC: IDA, PMID: 11430832); GO_0004674 (EC: TAS); GO_0005515 (EC: IPI, PMID: 12595760); GO_0005524 (EC: IDA, PMID: 12805220); GO_0005634 (EC: IDA); GO_0005737 (EC: IDA, PMID: 11430832); GO_0005739 (EC: IDA, PMID: 11430832); GO_0005829 (EC: ISS); GO_0005829 (EC: TAS); GO_0006112 (EC: TAS); GO_0006468 (EC: IDA, PMID: 12805220); GO_0006914 (EC: IEA); GO_0006974 (EC: IEA); GO_0007050 (EC: IDA, PMID: 12805220); GO_0007050 (EC: TAS); GO_0007286 (EC: IEA); GO_0007409 (EC: IEA); GO_0008285 (EC: IMP, PMID: 17216128); GO_0008286 (EC: TAS); GO_0010212 (EC: ISS); GO_0016020 (EC: ISS); GO_0030010 (EC: ISS); GO_0030111 (EC: IEA); GO_0030275 (EC: IEA); GO_0030295 (EC: IDA, PMID: 19892943); GO_0030308 (EC: ISS); GO_0030511 (EC: IMP, PMID: 18311138); GO_0032147 (EC: IDA, PMID: 18854309); GO_0032147 (EC: IEA); GO_0032403 (EC: IEA); GO_0033762 (EC: IEA); GO_0033993 (EC: IEA); GO_0036398 (EC: IEA); GO_0036399 (EC: IEA); GO_0042304 (EC: TAS); GO_0042593 (EC: ISS); GO_0043276 (EC: IMP, PMID: 19622832); GO_0044281 (EC: TAS); GO_0045059 (EC: IEA); GO_0045722 (EC: IEA); GO_0046777 (EC: IDA, PMID: 11430832); GO_0050731 (EC: IEA); GO_0050772 (EC: IEA); GO_0050852 (EC: IEA); GO_0051291 (EC: IEA); GO_0051645 (EC: IEA); GO_0051896 (EC: IEA); GO_0060070 (EC: IEA); GO_0060770 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0072332 (EC: IDA, PMID: 11430832) PMID: 8889548; 8988175; 9425897; 9428765; 9537235; 9760200; 9837816; 10208439; 10362809; 10408777; 10508479; 10642499; 10642527; 11297520; 11430832; 11445556; 11668633; 11733352; 11741830; 11853558; 12097271; 12218179; 12234250; 12477932; 12489981; 12533684; 12552571; 12595760; 12753905; 12805220; 12847291; 12879020; 12912948; 14511394; 14511408; 14517247; 14517248; 14668798; 14676191; 14702039; 14976552; 14985505; 15077168; 15121768; 15183188; 15188174; 15231735; 15287029; 15292028; 15331174; 15485651; 15489334; 15561763; 15607222; 15608654; 15617552; 15731909; 15733851; 15774015; 15800014; 15987703; 16054041; 16169070; 16287113; 16311241; 16396636; 16407220; 16407837; 16540748; 16580634; 16582077; 16648371; 16822578; 16882735; 16912160; 16927138; 16953221; 17010524; 17026623; 17098823; 17108107; 17114342; 17212587; 17216128; 17234589; 17244606; 17319781; 17344591; 17384680; 17573348; 17575127; 17599048; 17637250; 17641416; 17676035; 17711506; 17766436; 17884763; 17921699; 17928927; 17950019; 18000088; 18029348; 18199157; 18245474; 18256292; 18303014; 18311138; 18321849; 18403917; 18483235; 18495044; 18594528; 18600394; 18676680; 18681789; 18687677; 18794113; 18854309; 18854318; 19029933; 19056867; 19068194; 19145097; 19165201; 19170196; 19177591; 19204826; 19229701; 19250387; 19287990; 19340305; 19351817; 19369417; 19386264; 19407487; 19414597; 19463221; 19507030; 19513107; 19520843; 19584313; 19615099; 19615732; 19622832; 19625176; 19692168; 19724060; 19727776; 19892943; 19908348; 20010869; 20018878; 20020146; 20057966; 20082862; 20193846; 20207041; 20227367; 20301443; 20354225; 20357370; 20368287; 20368693; 20400510; 20418665; 20423848; 20424326; 20428811; 20435009; 20452353; 20489196; 20497868; 20559149; 20562859; 20623358; 20668229; 20682687; 20686846; 20722467; 20818976; 20864035; 20881644; 20939895; 20956321; 20974850; 21048031; 21102257; 21118512; 21150337; 21191146; 21191700; 21192934; 21241696; 21396365; 21450399; 21532627; 21572398; 21706049; 21816872; 21832049; 21860411; 21876548; 21994947; 22005930; 22118009; 22168747; 22226967; 22265968; 22270359; 22384927; 22412893; 22457270; 22460425; 22487816; 22543132; 22575644; 22635025; 22775437; 22814264; 22848740; 22928647; 22939624; 22942091; 22983157; 22986809; 22988252; 23027127; 23044421; 23074285; 23086944; 23207623; 23322200; 23367447; 23393134; 23399955; 23415580; 23430953; 23451056; 23526220; 23572524; 23592276; 23612973; 23637231; 23645358; 23648482; 23679304; 23706335; 23788249; 23810581; 23861764; 23878245; 23892522; 24074562; 24154639; 24285539; 24362629 serine/threonine kinase 11 Ensembl:ENSG00000118046 HGNC:11389 HPRD:03740 MIM:602216 Vega:OTTHUMG00000180118 STK11 Bin Zhao, Yue Liu, Oliver He MUNC18-1 NSEC1 P67 RBSEC1 UNC18 WEB: http://www.ncbi.nlm.nih.gov/gene STXBP1 syntaxin binding protein 1 6812 RP11-56D16.3 9q34.1 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000149 (EC: ISS); GO_0002576 (EC: IMP, PMID: 12773094); GO_0005737 (EC: ISS); GO_0005739 (EC: ISS); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 12773094); GO_0005886 (EC: ISS, Qualifier: colocalizes_with); GO_0006112 (EC: TAS); GO_0006904 (EC: IEA); GO_0007268 (EC: TAS); GO_0007269 (EC: TAS); GO_0007274 (EC: IEA); GO_0007412 (EC: ISS); GO_0010807 (EC: ISS); GO_0014047 (EC: TAS); GO_0015031 (EC: IEA); GO_0016188 (EC: ISS); GO_0017075 (EC: ISS); GO_0019901 (EC: IEA); GO_0019904 (EC: IEA); GO_0019905 (EC: IPI, PMID: 12773094); GO_0031091 (EC: IDA, PMID: 12773094); GO_0032229 (EC: ISS); GO_0042802 (EC: ISS); GO_0043234 (EC: ISS); GO_0043524 (EC: IEA); GO_0044281 (EC: TAS); GO_0044822 (EC: IDA); GO_0045956 (EC: IEA); GO_0047485 (EC: IEA); GO_0050796 (EC: TAS); GO_0050821 (EC: IEA); GO_0060292 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070527 (EC: IMP, PMID: 12773094) PMID: 7553862; 7698978; 7768895; 8108429; 8631738; 8824310; 9045631; 9115738; 9395480; 9545644; 9933594; 10194441; 10449403; 10746715; 10903204; 11927603; 12016213; 12093152; 12477932; 12519779; 12590134; 12773094; 12950453; 12963086; 14702039; 14702098; 14744865; 15175344; 15489225; 15489334; 15563604; 15592455; 15635413; 16413130; 16722236; 17200691; 17264080; 17363971; 17500595; 18268500; 18469812; 18617632; 18781797; 18854154; 19019082; 19056867; 19557857; 19686046; 20471030; 20681955; 20876469; 20887364; 21139048; 21204804; 21364700; 21565611; 21669024; 21762454; 21770924; 21832049; 21906983; 22211739; 22360420; 22939629; 23091057; 23409955; 23487749; 23858467 syntaxin binding protein 1 Ensembl:ENSG00000136854 HGNC:11444 HPRD:04235 MIM:602926 Vega:OTTHUMG00000020713 STXBP1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene SUOX sulfite oxidase 6821 12q13.2 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000096 (EC: TAS); GO_0000098 (EC: TAS); GO_0005758 (EC: IEA); GO_0005759 (EC: TAS); GO_0008482 (EC: TAS); GO_0009055 (EC: IEA); GO_0020037 (EC: IEA); GO_0030151 (EC: IEA); GO_0034641 (EC: TAS); GO_0043546 (EC: IEA); GO_0044281 (EC: TAS); GO_0070221 (EC: TAS) PMID: 7599189; 9428520; 9600976; 10519592; 12112661; 12368985; 12424234; 12477932; 12763039; 12832761; 14567685; 14729666; 15489334; 16140720; 16229463; 16344560; 16475804; 17366837; 17940249; 18177044; 18198356; 18529001; 18959753; 19850743; 20063894; 20491442; 20877624; 21988832; 22263579; 22885925; 22951725; 22975842 sulfite oxidase SUOX Bin Zhao, Yue Liu, Oliver He SYB2 VAMP-2 WEB: http://www.ncbi.nlm.nih.gov/gene VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 6844 17p13.1 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0005484 (EC: IBA); GO_0005515 (EC: IPI, PMID: 17196367); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 1976629); GO_0006112 (EC: TAS); GO_0006892 (EC: TAS); GO_0006906 (EC: IBA); GO_0007268 (EC: TAS); GO_0007269 (EC: TAS); GO_0008021 (EC: IBA); GO_0014047 (EC: TAS); GO_0016020 (EC: IDA); GO_0017156 (EC: IEA); GO_0017157 (EC: IBA); GO_0019905 (EC: IBA); GO_0030054 (EC: IEA); GO_0030136 (EC: IDA, PMID: 19478182); GO_0030666 (EC: TAS); GO_0030667 (EC: TAS); GO_0030672 (EC: IEA); GO_0031201 (EC: IDA, PMID: 19546860); GO_0043005 (EC: IEA); GO_0044267 (EC: TAS); GO_0044281 (EC: TAS); GO_0050796 (EC: TAS); GO_0060203 (EC: TAS); GO_0061024 (EC: TAS); GO_0061202 (EC: TAS); GO_0070083 (EC: TAS) PMID: 1976629; 7499863; 7553862; 7622514; 7835332; 7961655; 8011337; 8071310; 8125298; 8760387; 8770861; 8973549; 8999968; 9030619; 9341137; 9396746; 9657962; 9658161; 9817754; 9920726; 10036234; 10100611; 10194441; 10336434; 10370136; 10449403; 10662545; 10713150; 10820264; 10965122; 11031247; 11101518; 11252894; 11278762; 11295657; 11524423; 11786915; 11832227; 11842301; 11994746; 12093152; 12130530; 12181340; 12200427; 12417022; 12477932; 12485399; 12517971; 12750892; 12773094; 12828989; 12832401; 12847087; 12853575; 14702039; 15327778; 15610015; 16195891; 17001002; 17196367; 17207965; 17255364; 17313651; 17331077; 17356306; 18182011; 18511417; 18511418; 18512733; 18628682; 19478182; 19546860; 19557857; 19822142; 20416077; 20471030; 20676083; 21139048; 21565611; 21808019; 21890473; 21906983; 21963094; 21987572; 22053931; 22172278; 22505724; 22645275; 22890573; 22939629; 23000965; 24250222 vesicle-associated membrane protein 2 (synaptobrevin 2) Ensembl:ENSG00000220205 HGNC:12643 HPRD:01717 MIM:185881 Vega:OTTHUMG00000150254 VAMP2 Bin Zhao, Yue Liu, Oliver He MRX96 MRXSYP WEB: http://www.ncbi.nlm.nih.gov/gene SYP synaptophysin 6855 Xp11.23-p11.22 20140408 9606 X protein-coding Official from a nomenclature committee GO_0005215 (EC: IEA); GO_0006897 (EC: ISS); GO_0015485 (EC: IDA, PMID: 10620806); GO_0016188 (EC: NAS, PMID: 10620806); GO_0017075 (EC: IEA); GO_0030054 (EC: IEA); GO_0030285 (EC: NAS, PMID: 1975480); GO_0032403 (EC: IEA); GO_0042169 (EC: IEA); GO_0042734 (EC: IEA); GO_0042802 (EC: IEA); GO_0043234 (EC: IEA); GO_0044306 (EC: IEA); GO_0048168 (EC: IBA); GO_0048169 (EC: ISS); GO_0048172 (EC: ISS); GO_0048499 (EC: NAS, PMID: 10620806); GO_0048786 (EC: IEA); GO_0060076 (EC: IEA); GO_0071310 (EC: IEA); GO_2000474 (EC: ISS) PMID: 1908157; 1975480; 2163183; 3120152; 7534299; 7553862; 8547634; 8772779; 9112016; 9344658; 9889259; 9930883; 10541003; 10595912; 10620806; 11426054; 11472886; 11508360; 11786535; 12077483; 12097487; 12107411; 12137757; 12181340; 12403815; 12477932; 12485399; 12492469; 12493563; 12498786; 12575533; 12701886; 12826904; 14702039; 15489334; 15694236; 16082702; 16721760; 16807900; 16894395; 17005904; 17207965; 17331077; 17500595; 17724707; 17916412; 18006193; 18662323; 18771509; 19377476; 19652998; 19724850; 20847448; 21073671; 22055401; 22099865; 22210727; 22348818; 22449227; 22843923; 23022470; 23242284; 23292839; 23418554; 23763443; 24250222 synaptophysin Ensembl:ENSG00000102003 HGNC:11506 HPRD:02435 MIM:313475 Vega:OTTHUMG00000034557 SYP Bin Zhao, Yue Liu, Oliver He ADAM18 CD156B CSVP NISBD TACE WEB: http://www.ncbi.nlm.nih.gov/gene ADAM17 ADAM metallopeptidase domain 17 6868 2p25 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0001666 (EC: IDA, PMID: 18276953); GO_0001934 (EC: IMP, PMID: 18625725); GO_0002446 (EC: IC, PMID: 16034137); GO_0002467 (EC: ISS, PMID: 10433800); GO_0002690 (EC: IC, PMID: 16034137); GO_0004222 (EC: IDA); GO_0004222 (EC: IMP, PMID: 9034190); GO_0004222 (EC: TAS); GO_0005112 (EC: IDA); GO_0005138 (EC: IPI, PMID: 16034137); GO_0005178 (EC: IPI, PMID: 14970227); GO_0005515 (EC: IPI, PMID: 10527948); GO_0005737 (EC: IDA); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 17786981); GO_0005911 (EC: IDA, Qualifier: colocalizes_with, PMID: 14970227); GO_0005925 (EC: IDA, Qualifier: colocalizes_with, PMID: 14970227); GO_0006509 (EC: IDA, PMID: 17786981); GO_0006509 (EC: IMP, PMID: 12743035); GO_0006915 (EC: TAS); GO_0007155 (EC: IDA, PMID: 14970227); GO_0007173 (EC: IDA, PMID: 12743035); GO_0007173 (EC: TAS); GO_0007219 (EC: IEA); GO_0007220 (EC: IDA); GO_0008237 (EC: IDA, PMID: 12777399); GO_0008237 (EC: IMP, PMID: 12535668); GO_0008237 (EC: TAS); GO_0008270 (EC: IEA); GO_0008284 (EC: IMP, PMID: 18373975); GO_0009986 (EC: IDA, PMID: 18383040); GO_0010820 (EC: IMP, PMID: 18373975); GO_0015629 (EC: IDA, PMID: 17010968); GO_0016324 (EC: IDA, PMID: 16034137); GO_0017124 (EC: IEA); GO_0022617 (EC: TAS); GO_0030165 (EC: IPI, PMID: 12207026); GO_0030183 (EC: ISS, PMID: 10433800); GO_0030198 (EC: TAS); GO_0030307 (EC: IMP, PMID: 18373975); GO_0030335 (EC: IMP, PMID: 18373975); GO_0030511 (EC: ISS, PMID: 10433800); GO_0030574 (EC: TAS); GO_0031293 (EC: TAS); GO_0031659 (EC: IDA, PMID: 18483258); GO_0032496 (EC: IDA, PMID: 18383040); GO_0032587 (EC: IDA, Qualifier: colocalizes_with, PMID: 14970227); GO_0032717 (EC: IMP, PMID: 16034137); GO_0032722 (EC: IMP, PMID: 16034137); GO_0033025 (EC: ISS, PMID: 10433800); GO_0033077 (EC: ISS, PMID: 10433800); GO_0033627 (EC: IDA, PMID: 14970227); GO_0035313 (EC: IEP, PMID: 14970227); GO_0035625 (EC: IMP, PMID: 17655843); GO_0042493 (EC: ISS, PMID: 10433800); GO_0045121 (EC: IDA, PMID: 17010968); GO_0045741 (EC: IDA, PMID: 18483258); GO_0045741 (EC: IMP, PMID: 17655843); GO_0048011 (EC: TAS); GO_0048536 (EC: ISS, PMID: 10433800); GO_0048870 (EC: ISS, PMID: 10433800); GO_0051088 (EC: IDA, PMID: 14625290); GO_0051088 (EC: IMP, PMID: 18676862); GO_0051272 (EC: ISS, PMID: 10433800); GO_0055099 (EC: IDA, PMID: 17786981); GO_0060397 (EC: TAS); GO_0097190 (EC: TAS) PMID: 8889548; 9034190; 9034191; 9520379; 9574564; 9620803; 9774383; 9806848; 9920899; 10224132; 10433800; 10527948; 10799478; 10860581; 10882063; 11733179; 11741929; 11823465; 11988096; 12044879; 12058067; 12135369; 12147693; 12207026; 12441351; 12474981; 12477932; 12535668; 12568494; 12606576; 12621058; 12668732; 12706122; 12711607; 12714588; 12730960; 12743035; 12755693; 12777399; 12810728; 12832423; 12947092; 12972643; 14532978; 14625290; 14970227; 15066987; 15102849; 15146197; 15182369; 15280379; 15308656; 15309730; 15337756; 15534001; 15691827; 15784625; 15983030; 16034137; 16079149; 16148149; 16179345; 16210695; 16246259; 16279945; 16332693; 16336275; 16376986; 16478662; 16619241; 16641105; 16806063; 16900751; 16912185; 16942750; 16982746; 17010968; 17081983; 17155946; 17170699; 17227756; 17360351; 17405915; 17438092; 17608729; 17655843; 17714581; 17786981; 17942404; 17986144; 17999917; 18029348; 18167350; 18171982; 18238782; 18276953; 18281553; 18355445; 18373975; 18383040; 18396294; 18426733; 18442814; 18483258; 18490652; 18493210; 18600307; 18625725; 18636124; 18638486; 18676862; 18713734; 18818406; 18824549; 18922903; 18978678; 18979631; 19003995; 19082505; 19091752; 19124506; 19150341; 19154693; 19171023; 19253070; 19278423; 19296470; 19298600; 19299578; 19324423; 19376560; 19435795; 19482949; 19515085; 19535569; 19541935; 19564338; 19595713; 19633828; 19666115; 19704010; 19762488; 19772640; 19819120; 19843672; 19875451; 19913121; 19949420; 19959661; 20026129; 20059578; 20070837; 20118276; 20180536; 20184396; 20188673; 20221248; 20300049; 20300969; 20359533; 20379614; 20506406; 20551051; 20627730; 20628086; 20634891; 20679348; 20807704; 20811902; 20819075; 20863729; 20871631; 20922190; 21102583; 21153921; 21170088; 21175594; 21240579; 21268712; 21300824; 21359495; 21365281; 21386996; 21407195; 21423656; 21480393; 21501859; 21777519; 21837402; 21865167; 21890473; 21906983; 21925169; 21932060; 21949123; 22010916; 22018416; 22105359; 22139867; 22157716; 22200661; 22268729; 22319627; 22367719; 22384041; 22438584; 22479555; 22506015; 22550340; 22575642; 22613720; 22665490; 22668812; 22677042; 22689693; 22770404; 22772468; 22833676; 22927435; 22933306; 22934512; 22965144; 22967992; 23000965; 23011796; 23076445; 23105116; 23341882; 23349873; 23356982; 23384719; 23389772; 23415892; 23416080; 23441135; 23460612; 23475633; 23479224; 23487023; 23500026; 23521534; 23526433; 23545805; 23557259; 23563789; 23585341; 23625205; 23674691; 23684931; 23729230; 23746173; 23897050; 24044434; 24121505; 24189063; 24227843; 24286866 ADAM metallopeptidase domain 17 Ensembl:ENSG00000151694 HGNC:195 HPRD:04703 MIM:603639 Vega:OTTHUMG00000090425 ADAM17 Bin Zhao, Yue Liu, Oliver He PRO1557 PRO2086 TFQTL1 WEB: http://www.ncbi.nlm.nih.gov/gene TF transferrin 7018 PRO1400 3q22.1 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0001895 (EC: IEP); GO_0002576 (EC: TAS); GO_0005515 (EC: IPI, PMID: 15880641); GO_0005576 (EC: NAS, PMID: 14718574); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA); GO_0005769 (EC: IDA, PMID: 15880641); GO_0005770 (EC: IDA, PMID: 15880641); GO_0005905 (EC: IDA, PMID: 12857860); GO_0006879 (EC: TAS); GO_0007596 (EC: TAS); GO_0008199 (EC: IEA); GO_0009925 (EC: IDA, PMID: 15880641); GO_0009986 (EC: IDA, PMID: 16195351); GO_0010008 (EC: TAS); GO_0016023 (EC: IDA, PMID: 12857860); GO_0016324 (EC: IDA, PMID: 11208127); GO_0030139 (EC: IDA, PMID: 15229288); GO_0030168 (EC: TAS); GO_0031625 (EC: IEA); GO_0033572 (EC: TAS); GO_0034774 (EC: TAS); GO_0045178 (EC: IDA, PMID: 15880641); GO_0048471 (EC: IDA, PMID: 15880641); GO_0055037 (EC: IDA, PMID: 15880641); GO_0055085 (EC: TAS); GO_0070062 (EC: IDA, PMID: 19056867); GO_0072562 (EC: IDA) PMID: 1602151; 1809186; 1851757; 1932003; 2780570; 2874839; 3057819; 3106157; 3436225; 3678832; 3786138; 3858812; 5610700; 5711079; 5927288; 6268632; 6322780; 6457647; 6585826; 6690479; 6833213; 6953407; 7498159; 8125298; 8499451; 8889548; 9272172; 9312001; 9358047; 9570576; 9609685; 9760232; 9803271; 10029548; 10931525; 11027676; 11110675; 11208127; 11297622; 11436564; 11445282; 11606717; 11702220; 11703331; 11725818; 11749962; 11785295; 11800564; 11903051; 11920219; 11940510; 12044175; 12111369; 12135367; 12145410; 12165535; 12175089; 12207902; 12210842; 12223217; 12450380; 12458193; 12459033; 12473103; 12477932; 12522210; 12617162; 12626412; 12819023; 12857860; 12884526; 12939601; 12942785; 12951205; 14523999; 14567694; 14580189; 14614458; 14630798; 14643898; 14645044; 14702039; 14718574; 14757931; 14760718; 14980223; 15042587; 15060098; 15084671; 15111541; 15214509; 15214510; 15229288; 15252009; 15271890; 15292400; 15319290; 15327995; 15466165; 15489334; 15525538; 15536627; 15634274; 15648851; 15698609; 15880641; 15892129; 15924420; 15975770; 16047113; 16085060; 16169070; 16195351; 16199891; 16288727; 16300393; 16331960; 16335952; 16339299; 16354665; 16354686; 16373913; 16497717; 16538641; 16564538; 16740002; 17008590; 17011669; 17047092; 17116317; 17119318; 17192785; 17206377; 17496814; 17573378; 17601350; 17640392; 17711300; 17728504; 17976429; 17980706; 18022819; 18029348; 18045615; 18067952; 18097132; 18245657; 18257091; 18307987; 18344013; 18395717; 18442477; 18509548; 18597674; 18624398; 18654083; 18795173; 18813964; 18830724; 18835036; 18977241; 19021568; 19056867; 19084217; 19110265; 19165391; 19176989; 19219998; 19228837; 19250966; 19254567; 19281173; 19290554; 19515372; 19545871; 19572083; 19583819; 19650928; 19670106; 19693784; 19698254; 19761807; 19828835; 19838776; 19852572; 19856410; 19859668; 19913121; 19916167; 19917294; 19921860; 20029940; 20052609; 20064616; 20066543; 20096706; 20113254; 20118108; 20150920; 20164577; 20188707; 20215856; 20309589; 20360068; 20371432; 20379614; 20397659; 20410508; 20413850; 20444258; 20447458; 20534741; 20574532; 20587610; 20615872; 20628086; 20633231; 20634490; 20659343; 20708639; 20721554; 20738776; 20817350; 20880607; 21049900; 21103663; 21113232; 21150319; 21182205; 21208937; 21320285; 21376789; 21384276; 21389980; 21408069; 21422745; 21459485; 21483845; 21514009; 21643746; 21664032; 21665994; 21678080; 21785125; 21788477; 21811575; 21820158; 21866866; 21873562; 21881004; 21904748; 21988832; 22041858; 22079093; 22159020; 22191507; 22232660; 22323359; 22327295; 22343719; 22356162; 22424853; 22458330; 22722730; 22726553; 22819264; 22829284; 22861364; 22873711; 22923205; 23027680; 23089144; 23256035; 23588470; 23750785; 23817740; 23888904 transferrin Ensembl:ENSG00000091513 HGNC:11740 HPRD:01811 MIM:190000 Vega:OTTHUMG00000150356 TF Bin Zhao, Yue Liu, Oliver He MTTF1 MTTFA TCF6 TCF6L1 TCF6L2 TCF6L3 WEB: http://www.ncbi.nlm.nih.gov/gene TFAM transcription factor A, mitochondrial 7019 10q21 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0003682 (EC: IDA, PMID: 18063578); GO_0003700 (EC: IMP); GO_0005515 (EC: IPI, PMID: 12897151); GO_0005739 (EC: IDA); GO_0005759 (EC: TAS); GO_0006261 (EC: TAS, PMID: 8333869); GO_0006356 (EC: TAS, PMID: 8333869); GO_0006390 (EC: IMP); GO_0006390 (EC: TAS); GO_0006391 (EC: IDA); GO_0006391 (EC: TAS); GO_0008301 (EC: IDA); GO_0010467 (EC: TAS); GO_0031072 (EC: IEA); GO_0033108 (EC: IEA); GO_0042645 (EC: IDA, PMID: 18063578); GO_0044822 (EC: IDA); GO_0045893 (EC: IDA); GO_0070363 (EC: IDA, PMID: 19304746) PMID: 1610904; 1737790; 2035027; 2628167; 3211148; 3594571; 7599198; 7789991; 7849699; 7969115; 8061564; 8108407; 8166737; 8333869; 8441424; 8889548; 9063738; 9181464; 9309692; 9679658; 11457459; 11668394; 11964388; 11972329; 12068295; 12095695; 12127986; 12428064; 12477932; 12626705; 12686611; 12839966; 12897151; 12921794; 14969715; 15126285; 15464268; 15489334; 15509786; 15525513; 15526033; 15547250; 15965051; 16043643; 16202542; 16385451; 16428295; 16631115; 17167045; 17192785; 17339235; 17497594; 17537576; 17707600; 18028422; 18029348; 18063578; 18072287; 18248889; 18258228; 18430995; 18451773; 18642640; 18660489; 18716221; 18830724; 18980857; 19096125; 19148128; 19192634; 19209188; 19304746; 19322201; 19496804; 19624753; 19653005; 19681768; 19738201; 19885567; 19925850; 20186120; 20202876; 20410300; 20413850; 20432700; 20534741; 20562347; 20574532; 20643228; 20739229; 20843780; 20863902; 20877624; 20880607; 20972266; 20977898; 21081181; 21139048; 21145461; 21150319; 21453679; 21467167; 21514422; 21799244; 21890473; 21948790; 22037171; 22037172; 22098591; 22129993; 22266811; 22306509; 22354563; 22493245; 22675199; 22709542; 22841477; 22904065; 22910359; 23000965; 23012404; 23201127; 23398456; 23455922; 23456168; 24457600 transcription factor A, mitochondrial Ensembl:ENSG00000108064 HGNC:11741 HPRD:02702 MIM:600438 Vega:OTTHUMG00000018270 TFAM Bin Zhao, Yue Liu, Oliver He LBP1C LSF LSF1D SEF TFCP2C WEB: http://www.ncbi.nlm.nih.gov/gene TFCP2 transcription factor CP2 7024 12q13 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0003677 (EC: IEA); GO_0003700 (EC: TAS, PMID: 8157699); GO_0005575 (EC: ND); GO_0005634 (EC: IEA); GO_0006351 (EC: IEA); GO_0006357 (EC: TAS, PMID: 8157699) PMID: 1732747; 7828600; 8035790; 8114710; 8157699; 8289393; 8586452; 9371597; 9685356; 10455131; 10888618; 11001930; 11003662; 11283204; 11574690; 11865070; 11884454; 11940654; 12393799; 12477932; 12555245; 12661759; 15489334; 15857981; 16169070; 16263792; 16272261; 16344560; 16648487; 16710089; 16713569; 16973241; 17456737; 17902044; 18164103; 18307033; 18629613; 18787404; 19471022; 19505873; 19889475; 19902333; 20195357; 20211142; 20404171; 20562859; 20661472; 21139048; 21703197; 21876634; 22167195; 22242598; 22396589 transcription factor CP2 Ensembl:ENSG00000135457 HGNC:11748 HPRD:01790 MIM:189889 Vega:OTTHUMG00000169621 TFCP2 Bin Zhao, Yue Liu, Oliver He G-ALPHA-h GNAH HEL-S-45 TG2 TGC WEB: http://www.ncbi.nlm.nih.gov/gene TGM2 transglutaminase 2 7052 RP5-1054A22.2 20q12 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0001974 (EC: IEA); GO_0003810 (EC: ISS); GO_0005515 (EC: IPI, PMID: 16301118); GO_0005525 (EC: IEA); GO_0005739 (EC: IEA); GO_0005886 (EC: IEA); GO_0018153 (EC: IEA); GO_0019904 (EC: IEA); GO_0043065 (EC: IEA); GO_0043123 (EC: IEA); GO_0043277 (EC: IDA, PMID: 19628791); GO_0045785 (EC: ISS); GO_0046872 (EC: IEA); GO_0048661 (EC: IEA); GO_0050729 (EC: IEA); GO_0051260 (EC: IEA); GO_0051482 (EC: IEA); GO_0060445 (EC: IEA); GO_0060662 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1353685; 1358880; 1670766; 1670773; 7688299; 7730416; 7906657; 7912692; 8611626; 9060478; 9252372; 9315663; 9442029; 9512491; 9973324; 10100610; 10518533; 10521459; 10556977; 10561600; 10611475; 10684262; 10922377; 10958788; 10963790; 11013236; 11258932; 11350930; 11390390; 11442349; 11686302; 11742196; 11762979; 11780052; 11829448; 11867708; 11867764; 12061780; 12093810; 12205028; 12368090; 12387450; 12410804; 12438565; 12477932; 12527383; 12528814; 12698366; 12743114; 12853457; 12960346; 14631123; 14747475; 14752105; 14985437; 15001552; 15069073; 15199098; 15201665; 15220331; 15231748; 15272014; 15362860; 15460447; 15471861; 15489334; 15556610; 15585642; 15592455; 15691824; 15715085; 15746535; 15752564; 15886239; 16146723; 16146727; 16146777; 16153302; 16212417; 16285941; 16300411; 16301118; 16313886; 16338459; 16368540; 16368554; 16382148; 16407273; 16439457; 16449978; 16522628; 16720350; 16757564; 16826431; 16914140; 16951195; 17043648; 17171363; 17189522; 17228174; 17314516; 17374730; 17403029; 17440814; 17442486; 17476115; 17609251; 17625111; 17671187; 17711877; 17762854; 17890909; 17924658; 17939176; 18052077; 18092889; 18174247; 18235007; 18312620; 18353867; 18375543; 18381937; 18474442; 18490773; 18499669; 18505736; 18544639; 18561261; 18584285; 18587533; 18632639; 18667446; 18673368; 18793760; 18804908; 18809380; 18849643; 18923241; 19013523; 19056867; 19182256; 19183553; 19278990; 19324884; 19342211; 19403524; 19542224; 19562471; 19619546; 19625650; 19628791; 19632032; 19655169; 19657147; 19680746; 19738201; 19756726; 19838207; 19840940; 19878304; 19912255; 19931242; 19937343; 20007697; 20033322; 20052409; 20080707; 20156196; 20371597; 20437185; 20450916; 20450932; 20488756; 20489165; 20547769; 20596752; 20615646; 20659425; 20665636; 20676023; 20717931; 20731657; 20731658; 20739659; 20874003; 20926141; 20929862; 20967228; 21036168; 21036738; 21124911; 21129482; 21139048; 21226238; 21252943; 21304968; 21359202; 21441900; 21525012; 21625219; 21678409; 21757696; 21777419; 21818567; 21830119; 21832049; 21840417; 21900206; 21908620; 21935707; 21943122; 21963846; 21967801; 21971542; 21984378; 21988832; 22038180; 22080209; 22083892; 22086212; 22089883; 22118674; 22130737; 22139411; 22160262; 22198767; 22220471; 22220472; 22220474; 22220475; 22220476; 22220477; 22220479; 22225906; 22228808; 22231926; 22268729; 22298777; 22320917; 22322858; 22326684; 22364871; 22366952; 22382775; 22385244; 22418443; 22442151; 22451718; 22458929; 22460364; 22493284; 22652528; 22698685; 22750506; 22782215; 22863883; 22921425; 22923476; 23085038; 23085087; 23122413; 23185316; 23200849; 23224146; 23276939; 23290789; 23454274; 23538006; 23576428; 23640056; 23730209; 23765377; 23817628; 23853482; 23941696; 24052076; 24191290 transglutaminase 2 Ensembl:ENSG00000198959 HGNC:11778 HPRD:01825 MIM:190196 Vega:OTTHUMG00000032437 TGM2 Bin Zhao, Yue Liu, Oliver He DYT14 DYT5b TYH WEB: http://www.ncbi.nlm.nih.gov/gene TH tyrosine hydroxylase 7054 11p15.5 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0001666 (EC: IDA, PMID: 17520326); GO_0001963 (EC: ISS); GO_0001975 (EC: IEA); GO_0003007 (EC: NAS, PMID: 12113410); GO_0004511 (EC: IDA, PMID: 11943812); GO_0004511 (EC: TAS); GO_0005515 (EC: IPI, PMID: 11943812); GO_0005634 (EC: ISS); GO_0005737 (EC: IDA, PMID: 10907721); GO_0005739 (EC: IEA); GO_0005790 (EC: IDA, PMID: 12457228); GO_0005829 (EC: TAS); GO_0006585 (EC: NAS, PMID: 10907721); GO_0006631 (EC: IEA); GO_0006665 (EC: IEA); GO_0007507 (EC: ISS); GO_0007601 (EC: ISS); GO_0007605 (EC: IEA); GO_0007612 (EC: ISS); GO_0007613 (EC: ISS); GO_0007617 (EC: IEA); GO_0007626 (EC: ISS); GO_0008016 (EC: ISS); GO_0008021 (EC: IEA); GO_0008198 (EC: IEA); GO_0008199 (EC: IEA); GO_0009414 (EC: IEA); GO_0009416 (EC: IEA); GO_0009635 (EC: IEA); GO_0009651 (EC: IEA); GO_0009653 (EC: TAS, PMID: 7715703); GO_0009887 (EC: ISS); GO_0009898 (EC: IDA, PMID: 12457228); GO_0010043 (EC: IEA); GO_0010259 (EC: IEA); GO_0014823 (EC: IEA); GO_0015842 (EC: IEA); GO_0016137 (EC: IEA); GO_0016597 (EC: IEA); GO_0018963 (EC: IEA); GO_0019825 (EC: IEA); GO_0019904 (EC: IEA); GO_0021987 (EC: IEA); GO_0030425 (EC: IEA); GO_0031410 (EC: IDA, PMID: 12457228); GO_0031667 (EC: IEA); GO_0032355 (EC: IEA); GO_0032496 (EC: IEA); GO_0033076 (EC: IEA); GO_0033162 (EC: IDA, PMID: 12631248); GO_0034617 (EC: IEA); GO_0034641 (EC: TAS); GO_0035176 (EC: IEA); GO_0035240 (EC: IEA); GO_0035690 (EC: IEA); GO_0042136 (EC: IEA); GO_0042214 (EC: IEA); GO_0042416 (EC: IDA, PMID: 12457228); GO_0042418 (EC: IDA, PMID: 12457228); GO_0042421 (EC: IDA, PMID: 12457228); GO_0042423 (EC: TAS); GO_0042462 (EC: ISS); GO_0042745 (EC: IEA); GO_0042755 (EC: IEA); GO_0043005 (EC: IDA, PMID: 17135716); GO_0043195 (EC: IEA); GO_0043204 (EC: ISS); GO_0043434 (EC: IEA); GO_0043473 (EC: TAS, PMID: 12631248); GO_0044281 (EC: TAS); GO_0045471 (EC: IDA, PMID: 18343820); GO_0045472 (EC: IEA); GO_0046684 (EC: IEA); GO_0048596 (EC: ISS); GO_0051412 (EC: IEA); GO_0051602 (EC: IEA); GO_0052314 (EC: IEA); GO_0071287 (EC: IEA); GO_0071316 (EC: IEA); GO_0071333 (EC: IEA); GO_0071363 (EC: IEA) PMID: 33381; 1347949; 1973163; 2872999; 2874140; 2882428; 2887169; 2888085; 2892528; 2892893; 2896667; 2902075; 2905129; 6137760; 6150037; 7715703; 7789962; 7814018; 7901013; 8101641; 8528210; 8817341; 8889548; 9613851; 9703425; 9754624; 9920892; 10391209; 10660577; 10907721; 11246459; 11326301; 11359875; 11738155; 11834745; 11943812; 12113410; 12358785; 12421349; 12428766; 12457228; 12477932; 12493595; 12527603; 12571119; 12576454; 12610512; 12631248; 12759555; 12782971; 12891655; 14570886; 14651963; 14651989; 14675149; 14739699; 14749349; 15077008; 15135070; 15303408; 15468323; 15476168; 15722952; 15735319; 15736042; 15744773; 15898085; 15953356; 16139102; 16251897; 16252282; 16338639; 16344718; 16360899; 16445854; 16447258; 16516890; 16636198; 16643317; 16644734; 16731528; 16741719; 16764822; 16887311; 17018139; 17135716; 17194738; 17195153; 17329957; 17391063; 17466074; 17520326; 17698383; 17698732; 17784840; 17869399; 17926059; 17948905; 17972051; 17985144; 17988588; 18023073; 18058633; 18085551; 18181650; 18208403; 18270970; 18343820; 18534229; 18554280; 18574609; 18583979; 18814238; 18979915; 19120120; 19125082; 19156168; 19189602; 19221445; 19224593; 19285077; 19352218; 19360691; 19367319; 19448984; 19491146; 19491717; 19604093; 19674121; 19693267; 19703902; 19761814; 19767753; 19772578; 19801645; 19815691; 19833152; 19874574; 19913121; 19958792; 20046397; 20056467; 20067853; 20124442; 20132525; 20146650; 20163778; 20198643; 20301610; 20468064; 20564319; 20571875; 20602615; 20628086; 20646572; 20675101; 20706199; 20734064; 20809526; 20818075; 20838244; 20938049; 21083670; 21087208; 21158937; 21265843; 21368136; 21392500; 21407269; 21656370; 21815951; 22001923; 22002062; 22066143; 22083667; 22272358; 22336227; 22583432; 22691284; 22815559; 23182718; 23444366; 23481708; 23647419; 23762320; 23936387; 24055376; 24168553 tyrosine hydroxylase Ensembl:ENSG00000180176 HGNC:11782 HPRD:01865 MIM:191290 Vega:OTTHUMG00000009559 TH Bin Zhao, Yue Liu, Oliver He EP24.15 MEPD_HUMAN MP78 TOP WEB: http://www.ncbi.nlm.nih.gov/gene THOP1 thimet oligopeptidase 1 7064 19p13.3 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0004222 (EC: IEA); GO_0005515 (EC: IPI, PMID: 19614740); GO_0005737 (EC: IEA); GO_0006518 (EC: IEA); GO_0042277 (EC: IEA); GO_0046872 (EC: IEA) PMID: 7639763; 8286339; 8373360; 8824811; 9790774; 10415366; 10504294; 10541437; 10969067; 10993116; 11479311; 12477932; 12502762; 12648459; 14702039; 14998993; 15057824; 15231747; 15328361; 15376229; 15489334; 17251185; 18571100; 19282285; 19614740; 21139048; 21151101; 21890473; 21906983; 21963094; 22053931; 22796113; 22863883; 22939629; 23708739; 24250222 thimet oligopeptidase 1 Ensembl:ENSG00000172009 HGNC:11793 HPRD:03072 MIM:601117 Vega:OTTHUMG00000180492 THOP1 Bin Zhao, Yue Liu, Oliver He AR7 CHNG6 EAR7 ERB-T-1 ERBA ERBA1 NR1A1 THRA1 THRA2 c-ERBA-1 WEB: http://www.ncbi.nlm.nih.gov/gene THRA thyroid hormone receptor, alpha 7067 17q11.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0001502 (EC: IEA); GO_0001503 (EC: IEA); GO_0002153 (EC: IEA); GO_0002155 (EC: IEA); GO_0003700 (EC: IDA, PMID: 18052923); GO_0003707 (EC: IEA); GO_0004887 (EC: IDA, PMID: 15466465); GO_0005515 (EC: IPI, PMID: 10866662); GO_0005634 (EC: IDA, PMID: 19158403); GO_0005654 (EC: TAS); GO_0005829 (EC: IDA, PMID: 19158403); GO_0006357 (EC: IDA, PMID: 18052923); GO_0006366 (EC: IDA, PMID: 8710870); GO_0006367 (EC: TAS); GO_0007611 (EC: IEA); GO_0008016 (EC: IEA); GO_0008050 (EC: IEA); GO_0008134 (EC: IPI, PMID: 8524305); GO_0008270 (EC: IEA); GO_0009409 (EC: IEA); GO_0009755 (EC: IDA, PMID: 18052923); GO_0010467 (EC: TAS); GO_0010831 (EC: IEA); GO_0017025 (EC: IDA, PMID: 8524305); GO_0017055 (EC: IDA, PMID: 8524305); GO_0019904 (EC: IPI, PMID: 9653119); GO_0030218 (EC: IEA); GO_0030878 (EC: IEA); GO_0031490 (EC: IEA); GO_0032403 (EC: IEA); GO_0033032 (EC: IEA); GO_0042994 (EC: IEA); GO_0043565 (EC: IEA); GO_0044212 (EC: IDA, PMID: 18052923); GO_0045892 (EC: IDA, PMID: 8710870); GO_0045925 (EC: IEA); GO_0045944 (EC: IEA); GO_0050994 (EC: IEA); GO_0060509 (EC: IEA); GO_0070324 (EC: IDA, PMID: 15466465); GO_0070324 (EC: IPI, PMID: 2879243); GO_2000143 (EC: IDA, PMID: 8524305) PMID: 1307263; 1314167; 1331778; 1517709; 1537303; 1850510; 2464749; 2539258; 2710139; 2879242; 2879243; 3357890; 3458521; 3672126; 3684612; 6323162; 6589608; 7566114; 7566127; 7609079; 7776974; 8036737; 8127707; 8524305; 8537364; 8616895; 8650544; 8710870; 8806651; 9115274; 9256431; 9267036; 9268132; 9405624; 9415406; 9440806; 9626662; 9627117; 9628876; 9653119; 9680361; 9717844; 9804773; 9849963; 10022432; 10037764; 10198638; 10207062; 10235266; 10379889; 10409738; 10480874; 10490654; 10508171; 10567404; 10610177; 10691735; 10733574; 10744685; 10847592; 10866662; 10877839; 10902817; 10903152; 10965896; 11117530; 11158331; 11266503; 11641275; 11713274; 11726557; 11861164; 11889044; 11889175; 12048199; 12082618; 12138181; 12231529; 12371907; 12388540; 12477932; 12805224; 12871948; 12874288; 12878587; 14576168; 14614212; 14729678; 15130509; 15131262; 15140878; 15249124; 15388935; 15466465; 15489334; 15604093; 15674337; 15757863; 15767343; 15802373; 15808511; 15941852; 16219912; 16781732; 16799563; 17065567; 17220280; 17242407; 17560756; 17577579; 17620012; 17641689; 17911173; 18052923; 18467449; 18562675; 18641393; 18655026; 18844476; 19144825; 19158403; 19360007; 19422879; 19427062; 19453261; 19519176; 19628582; 19730683; 19819978; 19853653; 19903799; 19926848; 20053725; 20141582; 20211142; 20231357; 20534741; 20691434; 20724312; 20736347; 21075170; 21389087; 21508093; 21529443; 21622534; 21654857; 21738480; 21868449; 21988832; 21997736; 22224817; 22930759; 23271024; 23300972; 23633213; 23940126; 24250222 thyroid hormone receptor, alpha Ensembl:ENSG00000126351 HGNC:11796 HPRD:07185 MIM:190120 Vega:OTTHUMG00000133332 THRA Bin Zhao, Yue Liu, Oliver He CLGI EPA EPO HCI TIMP WEB: http://www.ncbi.nlm.nih.gov/gene TIMP1 TIMP metallopeptidase inhibitor 1 7076 RP1-230G1.3 Xp11.3-p11.23 20140408 9606 X protein-coding Official from a nomenclature committee GO_0002020 (EC: IEA); GO_0002576 (EC: TAS); GO_0005515 (EC: IPI, PMID: 16917503); GO_0005576 (EC: NAS, PMID: 1653055); GO_0005576 (EC: TAS); GO_0005604 (EC: IEA); GO_0007568 (EC: IEA); GO_0007596 (EC: TAS); GO_0008191 (EC: IDA, PMID: 12714508); GO_0008284 (EC: TAS, PMID: 3839290); GO_0010951 (EC: IDA, PMID: 12714508); GO_0022617 (EC: TAS); GO_0030168 (EC: TAS); GO_0030198 (EC: TAS); GO_0031093 (EC: TAS); GO_0034097 (EC: IEA); GO_0043066 (EC: IEA); GO_0043249 (EC: IEA); GO_0043434 (EC: IEA); GO_0046872 (EC: IEA); GO_0051045 (EC: IDA, PMID: 12714508); GO_1901164 (EC: IMP) PMID: 1420137; 1653055; 1730286; 2163605; 2171551; 2251898; 2921031; 3010309; 3460333; 3688834; 3839290; 3903517; 7507419; 8757599; 9063449; 9286280; 9288970; 9778693; 10071915; 10233411; 10441576; 10623524; 11279011; 11598182; 11606052; 11705862; 11762702; 11796725; 11876751; 11935340; 11940298; 12032189; 12034345; 12063180; 12081564; 12082592; 12147251; 12150976; 12218659; 12376362; 12406369; 12452001; 12475252; 12477932; 12479097; 12496489; 12538453; 12612199; 12614934; 12620441; 12626459; 12634064; 12651627; 12704667; 12714508; 12717827; 12771930; 12791318; 12834347; 12846741; 12861139; 12869573; 12873541; 12904305; 12921631; 12951656; 12970724; 14517716; 14605322; 14622947; 14630798; 14648584; 14652000; 14661256; 14669348; 14688084; 14710472; 14734567; 14871825; 14962256; 14973177; 14983226; 15028476; 15051730; 15073104; 15161657; 15225209; 15248826; 15277439; 15287862; 15313474; 15340161; 15363817; 15363818; 15465038; 15479729; 15485866; 15489334; 15494493; 15515157; 15516987; 15530852; 15557756; 15616792; 15754326; 15754388; 15797648; 15818737; 15841325; 15867221; 15888067; 15890357; 15896974; 15944607; 16005367; 16019435; 16042227; 16061701; 16100012; 16103240; 16107690; 16169070; 16188099; 16191301; 16219294; 16248458; 16263699; 16269968; 16280123; 16288711; 16289162; 16303743; 16335952; 16372907; 16407831; 16410344; 16474379; 16496359; 16555295; 16615041; 16631927; 16740002; 16754484; 16767366; 16772717; 16786122; 16840178; 16864898; 16877361; 16880228; 16917503; 16931892; 16935611; 16940985; 16960901; 16996520; 17008230; 17009408; 17012236; 17045024; 17050530; 17071711; 17072372; 17114213; 17136882; 17162914; 17182940; 17192464; 17202148; 17205957; 17209789; 17222415; 17226791; 17299802; 17301822; 17340613; 17350093; 17380436; 17409012; 17456311; 17478562; 17489740; 17493602; 17543340; 17549663; 17564313; 17572998; 17589947; 17634538; 17660250; 17703334; 17726014; 17763191; 17786346; 17878270; 17893005; 17899257; 17920311; 17928006; 17998244; 18025061; 18034264; 18042068; 18049028; 18063811; 18159069; 18214300; 18217401; 18236174; 18273688; 18291374; 18292822; 18298349; 18385523; 18391843; 18395263; 18474748; 18477480; 18487063; 18502033; 18630499; 18634035; 18636124; 18645261; 18683786; 18692810; 18704317; 18787947; 18850474; 18854176; 18945772; 18984437; 19012952; 19019896; 19020757; 19036126; 19134356; 19141395; 19246282; 19288452; 19331801; 19336475; 19358835; 19383295; 19383343; 19383344; 19387352; 19390929; 19430729; 19464975; 19506087; 19513566; 19524176; 19551542; 19560452; 19596921; 19608737; 19609944; 19629003; 19637058; 19653096; 19717938; 19723139; 19723899; 19728856; 19747478; 19758569; 19766963; 19781774; 19796534; 19814619; 19863693; 19875168; 19887890; 19889076; 19904223; 19911067; 19913121; 19927649; 20021931; 20030715; 20039537; 20041335; 20051489; 20095885; 20111696; 20164040; 20193458; 20215736; 20298300; 20305574; 20361393; 20371206; 20388222; 20423842; 20450704; 20452482; 20459644; 20484597; 20514432; 20533294; 20545111; 20545310; 20556397; 20584750; 20587546; 20595097; 20616161; 20628086; 20628624; 20646231; 20654099; 20655547; 20673868; 20685094; 20707923; 20798956; 20838751; 20853162; 20854182; 20889295; 20921293; 21041986; 21086628; 21094936; 21115936; 21128246; 21139048; 21163810; 21165404; 21167221; 21211402; 21283828; 21427648; 21437624; 21437772; 21454617; 21463121; 21487066; 21506705; 21524282; 21535601; 21547130; 21586274; 21684102; 21709637; 21720458; 21731773; 21745383; 21763297; 21786179; 21858035; 21860087; 21881840; 21882477; 21903858; 21906983; 21928345; 21946941; 21963094; 21963718; 21969093; 21987572; 21993004; 21995626; 22016393; 22020222; 22051851; 22110238; 22122951; 22139647; 22177802; 22199358; 22200256; 22200690; 22200710; 22204652; 22223664; 22257687; 22268729; 22286923; 22289852; 22291969; 22305865; 22364921; 22397869; 22402936; 22427646; 22457727; 22465225; 22516898; 22532131; 22544540; 22547904; 22558080; 22645431; 22667130; 22671570; 22706255; 22712305; 22718114; 22739984; 22788708; 22820628; 22859303; 22883459; 22901654; 22906271; 22957045; 22965799; 22971139; 22975753; 22985578; 23000965; 23016931; 23043898; 23057632; 23060593; 23064462; 23107442; 23122949; 23158994; 23175213; 23179318; 23223421; 23318123; 23388475; 23407481; 23412981; 23457635; 23509357; 23522389; 23525523; 23548070; 23555182; 23557756; 23563628; 23583449; 23592002; 23650722; 23660069; 23673111; 23763354; 23768069; 23815085; 23817219; 23834019; 23881388; 23893334; 23967215; 23993112; 24039251; 24174628; 24330623; 24479343 TIMP metallopeptidase inhibitor 1 Ensembl:ENSG00000102265 HGNC:11820 HPRD:02371 MIM:305370 Vega:OTTHUMG00000021447 TIMP1 Bin Zhao, Yue Liu, Oliver He CD282 TIL4 WEB: http://www.ncbi.nlm.nih.gov/gene TLR2 toll-like receptor 2 7097 4q32 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0001666 (EC: IEA); GO_0001875 (EC: TAS, PMID: 11518816); GO_0002224 (EC: TAS); GO_0002238 (EC: IEA); GO_0002282 (EC: IEA); GO_0002687 (EC: IEA); GO_0002752 (EC: IEA); GO_0002755 (EC: TAS); GO_0004872 (EC: IDA, PMID: 11672593); GO_0004888 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10854325); GO_0005737 (EC: IDA, PMID: 19740627); GO_0005886 (EC: IDA, PMID: 19740627); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 9435236); GO_0006691 (EC: IEA); GO_0006915 (EC: TAS, PMID: 10426996); GO_0006954 (EC: IEA); GO_0006955 (EC: TAS, PMID: 10426995); GO_0007165 (EC: TAS, PMID: 11044375); GO_0007252 (EC: IDA, PMID: 19740627); GO_0008285 (EC: IEA); GO_0008329 (EC: IDA, PMID: 10384090); GO_0009636 (EC: IEA); GO_0009897 (EC: IEA); GO_0009986 (EC: IDA, PMID: 12443841); GO_0030177 (EC: IMP, PMID: 16601243); GO_0031663 (EC: TAS, PMID: 11518816); GO_0032289 (EC: IEA); GO_0032570 (EC: IEA); GO_0032695 (EC: IEA); GO_0032700 (EC: IEA); GO_0032722 (EC: IDA, PMID: 19740627); GO_0032728 (EC: ISS); GO_0032733 (EC: IEA); GO_0032735 (EC: ISS); GO_0032741 (EC: ISS); GO_0032755 (EC: IDA, PMID: 19740627); GO_0032757 (EC: IDA, PMID: 17128265); GO_0032760 (EC: ISS); GO_0032868 (EC: IEA); GO_0034123 (EC: IDA, PMID: 17128265); GO_0034134 (EC: TAS); GO_0034142 (EC: TAS); GO_0035354 (EC: IDA, PMID: 17889651); GO_0035355 (EC: IEA); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042346 (EC: IDA, PMID: 19740627); GO_0042495 (EC: IDA, PMID: 19931471); GO_0042496 (EC: IDA, PMID: 19931471); GO_0042497 (EC: IDA, PMID: 17889651); GO_0042498 (EC: IEA); GO_0042535 (EC: IEA); GO_0042834 (EC: IDA, PMID: 11986301); GO_0042892 (EC: IEA); GO_0042995 (EC: IEA); GO_0044130 (EC: IEA); GO_0044297 (EC: IEA); GO_0045087 (EC: TAS, PMID: 15356140); GO_0045429 (EC: IEA); GO_0045944 (EC: ISS); GO_0046209 (EC: IEA); GO_0046982 (EC: IDA, PMID: 17889651); GO_0048714 (EC: IEA); GO_0050715 (EC: IEA); GO_0050729 (EC: IC, PMID: 19740627); GO_0050830 (EC: IDA, PMID: 11521063); GO_0051092 (EC: IDA, PMID: 12594207); GO_0051770 (EC: ISS); GO_0052033 (EC: IEA); GO_0052063 (EC: IEA); GO_0060907 (EC: IEA); GO_0070542 (EC: IEA); GO_0070891 (EC: IEA); GO_0071221 (EC: TAS, PMID: 15356140); GO_0071223 (EC: IDA, PMID: 12594207); GO_0071224 (EC: IEA); GO_0071726 (EC: IDA, PMID: 19931471); GO_0071727 (EC: IDA, PMID: 19931471) PMID: 9435236; 9596645; 9751057; 10384090; 10395652; 10426995; 10426996; 10548109; 10854325; 10963608; 11035751; 11044375; 11081518; 11101877; 11160242; 11222859; 11276206; 11441107; 11476982; 11477091; 11518816; 11521063; 11561001; 11672593; 11724772; 11751856; 11782555; 11836257; 11842086; 11867630; 11867688; 11877429; 11894098; 11912201; 11932927; 11986301; 12023360; 12061629; 12077222; 12089142; 12163593; 12171914; 12207338; 12270725; 12356755; 12397021; 12437972; 12438323; 12443841; 12445799; 12471095; 12477932; 12525572; 12538701; 12540550; 12588460; 12594207; 12630564; 12646604; 12651614; 12663765; 12734363; 12734376; 12810071; 12816980; 12817025; 12860988; 12874236; 12941697; 12942028; 12946842; 12958190; 12966099; 12975352; 14500665; 14551607; 14607814; 14625308; 14651524; 14662888; 14673018; 14694183; 14706103; 14706104; 14707104; 14709406; 14738464; 14966134; 14979495; 14981245; 14987294; 15007072; 15007351; 15007364; 15041961; 15044215; 15064239; 15107846; 15138193; 15146245; 15146246; 15146415; 15148609; 15155685; 15173186; 15175649; 15210811; 15214053; 15247273; 15247281; 15272059; 15276183; 15305230; 15319868; 15321997; 15322009; 15342637; 15356140; 15385480; 15456896; 15489334; 15489631; 15496409; 15501775; 15516360; 15521019; 15539529; 15583145; 15585865; 15657077; 15670752; 15670766; 15696084; 15699513; 15717270; 15726416; 15728506; 15731031; 15731043; 15731050; 15753758; 15760452; 15760459; 15778388; 15790341; 15793154; 15814732; 15864780; 15875151; 15910421; 15919371; 15955814; 15968536; 16002719; 16004610; 16024789; 16034117; 16035096; 16081826; 16107886; 16115866; 16146574; 16177110; 16179594; 16213463; 16230348; 16239565; 16242370; 16267105; 16270639; 16283346; 16290232; 16293622; 16336272; 16371473; 16374251; 16437124; 16439361; 16443229; 16455995; 16478769; 16482509; 16484229; 16497887; 16514159; 16517732; 16551363; 16601243; 16606450; 16608528; 16621981; 16629651; 16648973; 16712654; 16731773; 16751412; 16754684; 16754688; 16766226; 16767222; 16802353; 16818794; 16829623; 16843693; 16848791; 16861636; 16864901; 16878026; 16879199; 16880211; 16893894; 16901312; 16907704; 16950283; 16951309; 16955390; 16971956; 16973891; 16984411; 16988837; 17013994; 17020928; 17038528; 17045187; 17082324; 17082626; 17083795; 17096074; 17100621; 17126870; 17128265; 17130564; 17130790; 17172927; 17179672; 17187404; 17191175; 17196867; 17202359; 17205552; 17207025; 17227759; 17227763; 17229603; 17239937; 17258210; 17258734; 17264305; 17292969; 17301562; 17316370; 17322885; 17332447; 17389503; 17390084; 17395901; 17409197; 17443468; 17446209; 17456342; 17475853; 17481719; 17493681; 17522215; 17524268; 17531301; 17532476; 17554342; 17554618; 17555409; 17562761; 17563761; 17565608; 17565650; 17567674; 17588655; 17595233; 17599732; 17600044; 17624834; 17629003; 17640874; 17651447; 17652449; 17667860; 17669234; 17675516; 17676990; 17703412; 17709420; 17711514; 17713436; 17728249; 17854755; 17855767; 17855803; 17872459; 17877764; 17878165; 17878330; 17889651; 17892476; 17908769; 17913539; 17914947; 17916356; 17916440; 17928056; 17934735; 17934843; 17942642; 17956467; 17964520; 17967853; 17974158; 17984211; 18001294; 18006661; 18025115; 18028450; 18029454; 18040078; 18054497; 18056480; 18062119; 18067993; 18073264; 18089358; 18159247; 18167552; 18175935; 18177245; 18180796; 18191935; 18195069; 18201568; 18218857; 18219831; 18221795; 18234309; 18249133; 18266466; 18268386; 18275280; 18292749; 18295348; 18312481; 18325643; 18349186; 18354224; 18359883; 18368233; 18369480; 18394314; 18406368; 18411230; 18414649; 18419772; 18423053; 18424702; 18438411; 18441280; 18442320; 18445187; 18451040; 18454672; 18458086; 18458151; 18461142; 18474641; 18495130; 18516040; 18547625; 18549457; 18559343; 18565796; 18566366; 18571457; 18583567; 18596023; 18602432; 18618036; 18625015; 18641349; 18650783; 18651887; 18676680; 18678660; 18680520; 18684966; 18686608; 18704103; 18714935; 18722665; 18755634; 18765807; 18769358; 18773284; 18776592; 18802114; 18809506; 18810425; 18813073; 18818748; 18832719; 18846558; 18925411; 18930806; 18942754; 18946062; 18952897; 18975326; 18978205; 18983769; 19001446; 19012493; 19014987; 19015258; 19016779; 19019335; 19029192; 19033535; 19050632; 19061090; 19071087; 19096003; 19103770; 19106411; 19111445; 19120068; 19120486; 19120490; 19120971; 19121950; 19124728; 19128592; 19134118; 19139093; 19139198; 19141294; 19148143; 19148938; 19164296; 19167431; 19170196; 19172872; 19195606; 19196344; 19197942; 19200604; 19220214; 19247692; 19254290; 19258923; 19265130; 19275590; 19279330; 19280717; 19299164; 19306954; 19317913; 19336475; 19342676; 19378782; 19381722; 19392987; 19401382; 19401779; 19407153; 19412702; 19420105; 19423540; 19447045; 19454663; 19454721; 19455302; 19458089; 19479087; 19493410; 19503839; 19505919; 19509286; 19509287; 19522765; 19527514; 19528164; 19539691; 19541348; 19542461; 19543380; 19543401; 19545686; 19552525; 19554026; 19564644; 19573080; 19574958; 19592497; 19596998; 19597734; 19617348; 19622038; 19625176; 19627277; 19631014; 19635908; 19638314; 19648269; 19684606; 19686607; 19692168; 19693643; 19701803; 19723394; 19740627; 19758322; 19763595; 19766998; 19771447; 19771452; 19773279; 19796535; 19804908; 19810822; 19812189; 19814623; 19819943; 19830732; 19835594; 19843711; 19844258; 19849713; 19855253; 19874421; 19888805; 19913121; 19915052; 19917706; 19924287; 19931471; 19933854; 19948716; 19948975; 19948979; 19950169; 19953283; 19953876; 19956717; 19995893; 20002809; 20007698; 20011697; 20016852; 20020500; 20024498; 20041977; 20044219; 20056178; 20056792; 20057905; 20063104; 20067962; 20085599; 20090572; 20092701; 20098705; 20100933; 20109309; 20113368; 20113509; 20120936; 20147631; 20153491; 20154223; 20167866; 20169003; 20174873; 20194452; 20196868; 20198307; 20207250; 20222908; 20227302; 20232093; 20233331; 20237496; 20298136; 20307689; 20337891; 20338659; 20348427; 20348497; 20357716; 20363151; 20375602; 20379614; 20382708; 20384861; 20388081; 20388552; 20400509; 20402671; 20404927; 20406964; 20438785; 20441518; 20441696; 20448286; 20452482; 20454607; 20456615; 20463618; 20463690; 20472010; 20473500; 20483368; 20492495; 20492496; 20497180; 20497485; 20500688; 20503287; 20520770; 20525885; 20534434; 20549240; 20560984; 20568250; 20577092; 20577149; 20578945; 20581745; 20595247; 20598754; 20599261; 20601596; 20604744; 20614721; 20616112; 20626741; 20628086; 20628182; 20634913; 20646321; 20646366; 20646633; 20650298; 20673868; 20685742; 20686034; 20713893; 20714796; 20726329; 20730440; 20740673; 20797905; 20799043; 20800577; 20802527; 20805788; 20813038; 20815312; 20818954; 20818961; 20819778; 20821041; 20835611; 20849532; 20861605; 20877569; 20927103; 20933500; 20937339; 20940109; 20946179; 20947433; 20977567; 21048031; 21055975; 21060793; 21078852; 21097451; 21105983; 21107351; 21128061; 21134221; 21148810; 21163333; 21167252; 21168672; 21173310; 21178007; 21179035; 21188584; 21191086; 21206505; 21220755; 21224062; 21239179; 21246489; 21276007; 21281869; 21298446; 21303685; 21320563; 21321205; 21330474; 21343392; 21356257; 21371045; 21398611; 21406030; 21417682; 21424379; 21425908; 21426724; 21426732; 21437199; 21438704; 21443084; 21447101; 21454596; 21455638; 21460227; 21468605; 21474333; 21481769; 21483768; 21493395; 21500195; 21515468; 21518510; 21544941; 21563293; 21570715; 21570717; 21573018; 21600098; 21621299; 21625017; 21646294; 21673343; 21705332; 21709150; 21721932; 21768114; 21768203; 21775336; 21775683; 21783307; 21789185; 21789730; 21794115; 21825064; 21827211; 21829704; 21834467; 21841130; 21843566; 21845735; 21846836; 21848584; 21858161; 21883620; 21887520; 21897866; 21899704; 21902816; 21905008; 21923667; 21949112; 21950140; 21952587; 21956671; 21960283; 21978687; 21982724; 21989233; 21994405; 21998742; 22003201; 22021706; 22022564; 22030478; 22032785; 22041559; 22057691; 22067623; 22095710; 22100911; 22105995; 22126586; 22128242; 22133017; 22133266; 22166855; 22182736; 22186927; 22198949; 22210918; 22216191; 22219347; 22219617; 22221660; 22227093; 22229967; 22230402; 22251071; 22280448; 22292031; 22295065; 22303480; 22305616; 22309608; 22311043; 22330637; 22336003; 22359280; 22372604; 22402138; 22417709; 22429552; 22442665; 22453525; 22466961; 22467654; 22468087; 22491449; 22496225; 22513358; 22521894; 22523426; 22552867; 22555189; 22556042; 22560646; 22561467; 22608210; 22613713; 22623652; 22662111; 22673208; 22697069; 22707717; 22737215; 22777994; 22778396; 22792230; 22795952; 22815694; 22825445; 22842950; 22844428; 22848741; 22865347; 22870312; 22952638; 22963587; 22964787; 22982459; 22992740; 22998942; 22999059; 23026048; 23028414; 23062767; 23068105; 23079657; 23083518; 23086127; 23091345; 23102403; 23132491; 23133361; 23166414; 23200752; 23206327; 23211828; 23213270; 23219913; 23223142; 23230212; 23233677; 23239925; 23244658; 23255565; 23259689; 23281696; 23285751; 23289617; 23304186; 23380629; 23398566; 23407387; 23417037; 23417289; 23418602; 23425749; 23430250; 23437263; 23463005; 23478027; 23484049; 23486465; 23489702; 23504312; 23534406; 23555011; 23565226; 23578092; 23589304; 23593431; 23599654; 23606791; 23614732; 23616573; 23619473; 23626692; 23629653; 23638011; 23643268; 23644137; 23657466; 23663325; 23668840; 23671673; 23680675; 23684765; 23722608; 23747679; 23765228; 23786414; 23787127; 23821954; 23830055; 23855294; 23861881; 23864765; 23866094; 23875738; 23908180; 23946637; 23980810; 23985798; 24011352; 24051092; 24080302; 24116867; 24255044; 24277938; 24617037 toll-like receptor 2 HGNC:11848 HPRD:04323 MIM:603028 TLR2 Bin Zhao, Yue Liu, Oliver He CD283 IIAE2 WEB: http://www.ncbi.nlm.nih.gov/gene TLR3 toll-like receptor 3 7098 4q35 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0000139 (EC: TAS); GO_0002224 (EC: TAS); GO_0002282 (EC: IEA); GO_0002756 (EC: TAS); GO_0003725 (EC: IDA, PMID: 16111635); GO_0003725 (EC: NAS, PMID: 12054664); GO_0004872 (EC: TAS, PMID: 10426995); GO_0004888 (EC: NAS, PMID: 12054664); GO_0005515 (EC: IPI, PMID: 16858407); GO_0005737 (EC: IDA, PMID: 19740627); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005789 (EC: TAS); GO_0005887 (EC: TAS, PMID: 9435236); GO_0006954 (EC: IEA); GO_0006972 (EC: NAS, PMID: 12054664); GO_0007165 (EC: TAS, PMID: 10426995); GO_0007249 (EC: TAS); GO_0007250 (EC: NAS, PMID: 12054664); GO_0007252 (EC: IDA, PMID: 19740627); GO_0008584 (EC: IEA); GO_0009597 (EC: NAS, PMID: 12054664); GO_0009986 (EC: IDA, Qualifier: NOT, PMID: 19740627); GO_0010008 (EC: TAS); GO_0016020 (EC: NAS, PMID: 12054664); GO_0032722 (EC: IDA, PMID: 19740627); GO_0032728 (EC: ISS); GO_0032735 (EC: ISS); GO_0032755 (EC: IDA, PMID: 19740627); GO_0032757 (EC: IDA, PMID: 17128265); GO_0032760 (EC: ISS); GO_0034123 (EC: IDA, PMID: 17128265); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034346 (EC: IEA); GO_0035458 (EC: IEA); GO_0035666 (EC: TAS); GO_0035690 (EC: IEA); GO_0036020 (EC: TAS); GO_0042346 (EC: IDA, PMID: 19740627); GO_0042742 (EC: TAS, PMID: 10426995); GO_0043065 (EC: IEA); GO_0043123 (EC: IEA); GO_0043330 (EC: IDA); GO_0045078 (EC: IDA, PMID: 16286015); GO_0045080 (EC: IEA); GO_0045087 (EC: TAS, PMID: 15356140); GO_0045356 (EC: IDA, PMID: 16286015); GO_0045359 (EC: IDA, PMID: 16286015); GO_0045359 (EC: IMP, PMID: 12054664); GO_0045671 (EC: NAS, PMID: 12133979); GO_0045944 (EC: ISS); GO_0046330 (EC: IEA); GO_0050729 (EC: IC, PMID: 19740627); GO_0051092 (EC: IEA); GO_0051607 (EC: TAS, PMID: 15356140); GO_0052033 (EC: IEA); GO_0071260 (EC: IEP, PMID: 19593445); GO_0071346 (EC: IEA); GO_0071360 (EC: IEA); GO_0097191 (EC: IDA); GO_0097527 (EC: IDA) PMID: 9435236; 10066798; 10426995; 10820283; 11561001; 11607032; 11782555; 12054664; 12133979; 12477932; 12509442; 12539043; 12609980; 12646618; 12672806; 12692549; 12855817; 14519765; 14557267; 14575692; 14729660; 14982987; 14987294; 15064760; 15107846; 15119015; 15153468; 15212709; 15226270; 15315972; 15340161; 15356140; 15502848; 15579900; 15652398; 15731229; 15737993; 15767394; 15778392; 15845391; 15935884; 15961631; 15972671; 16029432; 16035096; 16043704; 16111635; 16115877; 16144834; 16146574; 16160153; 16286015; 16289658; 16293707; 16344560; 16399790; 16424203; 16473828; 16482523; 16484229; 16533755; 16585585; 16628196; 16720699; 16847112; 16858407; 16877304; 16914605; 16935934; 16950283; 17043099; 17085778; 17128265; 17142768; 17142772; 17150911; 17178723; 17209042; 17254392; 17292969; 17301562; 17314152; 17434873; 17449641; 17521732; 17525119; 17534115; 17573354; 17602875; 17626075; 17660379; 17703412; 17786279; 17805015; 17851256; 17872438; 17878161; 17897319; 17908959; 17939877; 17947455; 17962643; 17962701; 17963596; 17964520; 17982077; 18021446; 18029758; 18172197; 18204787; 18253710; 18262679; 18325643; 18367536; 18385087; 18394314; 18437017; 18442983; 18508883; 18541719; 18544529; 18562533; 18566014; 18566393; 18568036; 18684960; 18686608; 18715647; 18725521; 18753640; 18775079; 18776324; 18776592; 18779317; 18810425; 18813073; 18818748; 18832709; 18849495; 18946062; 18949355; 18978302; 18988918; 19001446; 19016379; 19019335; 19035519; 19055649; 19120481; 19134117; 19164128; 19231996; 19234180; 19247444; 19254290; 19258923; 19265130; 19299748; 19362356; 19378782; 19423540; 19437550; 19475618; 19494321; 19505919; 19522763; 19527514; 19542247; 19593445; 19597128; 19625408; 19628747; 19631980; 19646728; 19656899; 19740627; 19741468; 19748983; 19752565; 19758322; 19769802; 19779021; 19795416; 19810822; 19833099; 19855253; 19878930; 19887600; 19890046; 19902255; 19914718; 19948350; 19951172; 19966137; 19966777; 20009359; 20047764; 20100933; 20124101; 20194452; 20197609; 20200155; 20227302; 20237496; 20309865; 20331378; 20367642; 20381870; 20406303; 20406964; 20422193; 20438785; 20452482; 20472559; 20483009; 20483744; 20483774; 20503287; 20514466; 20523058; 20588308; 20595247; 20604744; 20636339; 20639488; 20651983; 20673868; 20685081; 20691286; 20819670; 20832341; 20855885; 20957750; 20977567; 20978888; 21061265; 21079408; 21093032; 21129170; 21132533; 21148036; 21173679; 21179282; 21189260; 21216866; 21220319; 21223583; 21239167; 21245912; 21255094; 21266579; 21367858; 21398612; 21454254; 21474651; 21481769; 21498625; 21515789; 21563279; 21623661; 21646299; 21691053; 21695056; 21708001; 21712495; 21722947; 21730023; 21735101; 21802664; 21829730; 21839239; 21843566; 21844166; 21847628; 21903422; 21911421; 21911422; 21911501; 21911973; 21931545; 21949112; 21952237; 21960283; 21978158; 21990957; 21998457; 22016778; 22024499; 22030901; 22038398; 22039520; 22057682; 22065573; 22070917; 22102050; 22147891; 22174453; 22200507; 22205631; 22205660; 22260507; 22310660; 22323545; 22415225; 22421267; 22421964; 22457005; 22466005; 22479513; 22504413; 22537752; 22549436; 22552940; 22568929; 22572822; 22579623; 22590509; 22591330; 22611194; 22685032; 22745793; 22759966; 22762377; 22771581; 22825813; 22849850; 22851595; 22864531; 22865861; 22912896; 22944378; 22948160; 22950839; 22960172; 22989785; 23053995; 23056170; 23056470; 23076446; 23103873; 23115281; 23151015; 23166319; 23179584; 23220997; 23240626; 23245579; 23255072; 23255358; 23269203; 23290562; 23353987; 23369718; 23396947; 23404408; 23425350; 23467704; 23489702; 23497334; 23534905; 23541683; 23548575; 23647955; 23668802; 23673618; 23716670; 23717201; 23721942; 23723066; 23844087; 23908180; 23946637; 23962979; 24070541; 24198284 toll-like receptor 3 HGNC:11849 HPRD:04324 MIM:603029 TLR3 Bin Zhao, Yue Liu, Oliver He ARMD10 CD284 TLR-4 TOLL WEB: http://www.ncbi.nlm.nih.gov/gene TLR4 toll-like receptor 4 7099 9q33.1 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000187 (EC: ISS); GO_0001530 (EC: IMP, PMID: 16514062); GO_0001530 (EC: NAS, PMID: 10835634); GO_0001875 (EC: IDA, PMID: 19252480); GO_0002224 (EC: TAS); GO_0002322 (EC: IEA); GO_0002537 (EC: IEA); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0004872 (EC: TAS, PMID: 10426995); GO_0004888 (EC: NAS, PMID: 11970998); GO_0005515 (EC: IPI, PMID: 11441107); GO_0005737 (EC: IDA, PMID: 19740627); GO_0005886 (EC: IDA, PMID: 19740627); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 15027902); GO_0006955 (EC: TAS, PMID: 10426995); GO_0007249 (EC: TAS); GO_0007252 (EC: IDA, PMID: 19740627); GO_0009897 (EC: IDA, PMID: 16514062); GO_0010008 (EC: TAS); GO_0010572 (EC: ISS, PMID: 16514062); GO_0016046 (EC: NAS, PMID: 11254600); GO_0030890 (EC: IEA); GO_0031663 (EC: IDA, Qualifier: NOT, PMID: 10880523); GO_0031663 (EC: IGI, PMID: 10880523); GO_0032496 (EC: IC, PMID: 16514062); GO_0032496 (EC: IDA, PMID: 12594207); GO_0032497 (EC: IDA, PMID: 19252480); GO_0032609 (EC: IEA); GO_0032689 (EC: ISS); GO_0032700 (EC: ISS); GO_0032707 (EC: ISS); GO_0032715 (EC: ISS); GO_0032720 (EC: ISS); GO_0032722 (EC: IDA, PMID: 19740627); GO_0032727 (EC: ISS); GO_0032728 (EC: ISS); GO_0032729 (EC: ISS); GO_0032732 (EC: ISS); GO_0032733 (EC: ISS); GO_0032735 (EC: ISS); GO_0032755 (EC: IDA, PMID: 19740627); GO_0032757 (EC: IDA, PMID: 19740627); GO_0032760 (EC: ISS); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0035666 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042088 (EC: NAS, PMID: 11970998); GO_0042116 (EC: IMP, PMID: 10835634); GO_0042346 (EC: IDA, PMID: 19740627); GO_0042535 (EC: IDA, PMID: 17951129); GO_0042742 (EC: TAS, PMID: 10426995); GO_0043123 (EC: IEA); GO_0045084 (EC: IDA, PMID: 15027902); GO_0045087 (EC: TAS, PMID: 15356140); GO_0045348 (EC: IEA); GO_0045359 (EC: IEA); GO_0045416 (EC: IDA, PMID: 17951129); GO_0045429 (EC: IEA); GO_0045671 (EC: NAS, PMID: 12133979); GO_0045944 (EC: ISS); GO_0046330 (EC: IEA); GO_0046696 (EC: IDA, PMID: 19252480); GO_0048471 (EC: IDA, PMID: 15027902); GO_0050729 (EC: IC, PMID: 19740627); GO_0050829 (EC: IC, PMID: 16514062); GO_0051092 (EC: IDA, PMID: 12594207); GO_0051770 (EC: ISS); GO_0060729 (EC: ISS); GO_0060907 (EC: IEA); GO_0070373 (EC: ISS); GO_0070374 (EC: IEA); GO_0070430 (EC: IEA); GO_0070434 (EC: IEA); GO_0071222 (EC: ISS); GO_0071223 (EC: IEA); GO_0071260 (EC: IEP, PMID: 19593445) PMID: 9237759; 9435236; 9625770; 10359581; 10426995; 10465784; 10524757; 10734131; 10835634; 10880523; 10952994; 11081518; 11104518; 11254600; 11441107; 11466383; 11477091; 11490012; 11494169; 11514453; 11526399; 11529488; 11544529; 11561001; 11688988; 11706042; 11728442; 11743586; 11751856; 11782555; 11835533; 11836257; 11841848; 11842086; 11877429; 11893689; 11912201; 11923281; 11932926; 11932927; 11964313; 11970998; 11976338; 12045108; 12055604; 12089142; 12117914; 12124407; 12133979; 12165534; 12174084; 12193670; 12196527; 12270725; 12324469; 12324481; 12391239; 12397216; 12402214; 12404174; 12406828; 12411706; 12438323; 12444143; 12447442; 12477932; 12477953; 12495941; 12525572; 12552467; 12588460; 12591474; 12592402; 12594207; 12599057; 12622779; 12630564; 12646618; 12717385; 12724322; 12730365; 12734376; 12738639; 12742999; 12773175; 12773319; 12777373; 12782302; 12794153; 12796470; 12810071; 12832426; 12846053; 12855579; 12865424; 12874320; 12897738; 12923493; 12925853; 12941697; 12942028; 12957699; 12960171; 12964127; 14517278; 14519765; 14551607; 14556004; 14557267; 14563652; 14565959; 14578307; 14597728; 14600154; 14610481; 14625308; 14638766; 14651524; 14693986; 14699116; 14699155; 14706103; 14709406; 14715415; 14735148; 14738464; 14739370; 14764071; 14764599; 14987294; 15007351; 15016407; 15022344; 15027902; 15039334; 15041961; 15044215; 15069085; 15081257; 15087412; 15107846; 15132988; 15138173; 15143473; 15148609; 15155619; 15175334; 15175649; 15187145; 15190267; 15194649; 15207785; 15213237; 15225640; 15247281; 15258789; 15273551; 15276183; 15277575; 15292002; 15302104; 15305230; 15321997; 15337750; 15340161; 15341923; 15351720; 15356101; 15356140; 15356557; 15358455; 15367917; 15373967; 15385480; 15452251; 15456896; 15489631; 15509550; 15516360; 15520404; 15525557; 15528333; 15547160; 15557191; 15576653; 15591473; 15610077; 15614130; 15623538; 15632890; 15644417; 15647432; 15650037; 15655821; 15661045; 15665723; 15670831; 15691841; 15694388; 15695310; 15696495; 15699327; 15728517; 15752733; 15760452; 15760459; 15770725; 15778388; 15790341; 15796767; 15809303; 15829498; 15843568; 15845500; 15852007; 15863460; 15864121; 15866212; 15866876; 15875057; 15879290; 15882292; 15883205; 15905704; 15910421; 15910856; 15919371; 15927851; 15932772; 15953129; 15972671; 15973118; 16002719; 16006099; 16010583; 16019531; 16024789; 16044857; 16051275; 16085746; 16107886; 16135957; 16142747; 16146574; 16157088; 16157451; 16202743; 16213463; 16215326; 16219107; 16219455; 16239565; 16239841; 16246938; 16266379; 16266460; 16267105; 16270639; 16290232; 16301860; 16304445; 16338228; 16338476; 16343635; 16344560; 16357190; 16371473; 16385250; 16388712; 16393227; 16395111; 16397127; 16436969; 16437636; 16439361; 16441767; 16443229; 16461792; 16463649; 16467847; 16469362; 16487240; 16508260; 16514062; 16517732; 16523497; 16525349; 16552356; 16556150; 16567359; 16581829; 16585591; 16603631; 16606645; 16613760; 16629651; 16651628; 16706818; 16714144; 16717116; 16731773; 16738534; 16740140; 16751411; 16754682; 16754684; 16754725; 16779724; 16780707; 16785528; 16786156; 16802353; 16803995; 16818785; 16829202; 16830219; 16836908; 16837493; 16840031; 16843693; 16849487; 16878026; 16879054; 16879199; 16879239; 16888192; 16890863; 16907704; 16933467; 16936080; 16950283; 16954131; 16955390; 16961803; 16969132; 16971956; 16973891; 16982657; 16988837; 16990552; 17008589; 17015691; 17038528; 17044867; 17045043; 17055575; 17056597; 17057796; 17062130; 17083795; 17086894; 17096074; 17100621; 17100625; 17100974; 17101559; 17111814; 17121827; 17124436; 17130564; 17143969; 17151549; 17156435; 17157899; 17172927; 17179672; 17206636; 17220311; 17228323; 17229603; 17235555; 17237368; 17258210; 17258734; 17264400; 17292969; 17301271; 17301562; 17301819; 17304101; 17309585; 17309748; 17314284; 17314700; 17322885; 17324405; 17328955; 17332447; 17333217; 17344072; 17362744; 17381056; 17381401; 17384648; 17389503; 17389921; 17390084; 17395901; 17404865; 17414051; 17417801; 17431743; 17448042; 17449325; 17456342; 17462092; 17465679; 17476680; 17482427; 17493663; 17513785; 17524268; 17529905; 17530716; 17538633; 17545720; 17549384; 17555409; 17556642; 17559631; 17565323; 17579019; 17579031; 17587646; 17588655; 17592300; 17592301; 17595233; 17597463; 17599732; 17600225; 17623651; 17624583; 17625598; 17629003; 17652449; 17660297; 17675516; 17681703; 17699831; 17703412; 17707233; 17709420; 17709532; 17713436; 17718424; 17720800; 17724596; 17767165; 17803912; 17827066; 17849054; 17850411; 17854755; 17855767; 17855803; 17872459; 17877764; 17877801; 17878380; 17892476; 17908769; 17909078; 17914947; 17916356; 17921137; 17925445; 17927684; 17928056; 17934216; 17942642; 17947706; 17951129; 17956467; 17956942; 17962701; 17964520; 17964870; 17967488; 17977838; 17982277; 17992260; 17992634; 17996871; 17999935; 18000954; 18001295; 18008256; 18025155; 18029454; 18031543; 18034244; 18034897; 18040078; 18042837; 18044001; 18054497; 18056968; 18062119; 18062835; 18067993; 18070880; 18082569; 18084608; 18089358; 18092352; 18097881; 18172114; 18174680; 18178854; 18180278; 18180796; 18182917; 18192488; 18209079; 18209571; 18213697; 18221795; 18234118; 18234474; 18251133; 18252714; 18268386; 18275280; 18286551; 18288881; 18292749; 18295348; 18297073; 18298826; 18299127; 18304834; 18306470; 18307517; 18312481; 18325643; 18326860; 18338763; 18344712; 18345485; 18348860; 18360565; 18368233; 18381796; 18382655; 18385087; 18394314; 18395849; 18403647; 18408113; 18415752; 18422738; 18424732; 18437214; 18452992; 18458086; 18462799; 18493210; 18495130; 18509450; 18517079; 18519568; 18522803; 18523439; 18541719; 18543224; 18544275; 18546014; 18549457; 18549840; 18559343; 18565796; 18586872; 18590761; 18596029; 18608206; 18618036; 18622013; 18622290; 18633131; 18634146; 18634786; 18641349; 18649875; 18650420; 18650783; 18666712; 18670786; 18680223; 18680520; 18686608; 18690351; 18698233; 18712040; 18714935; 18723631; 18725521; 18728522; 18755634; 18763053; 18763295; 18769358; 18771998; 18773284; 18775079; 18782768; 18785522; 18806258; 18809506; 18810425; 18818748; 18825409; 18826495; 18826950; 18832719; 18835634; 18845299; 18846558; 18849341; 18925411; 18927069; 18928988; 18930806; 18936436; 18942754; 18945182; 18946062; 18948841; 18950592; 18972554; 18975326; 18978678; 18983635; 18987746; 18996347; 19001446; 19006850; 19012493; 19015224; 19015258; 19017994; 19029192; 19033535; 19035500; 19035519; 19037967; 19046305; 19048480; 19050632; 19060757; 19061090; 19064998; 19067129; 19067670; 19085953; 19096003; 19106585; 19108989; 19109197; 19112167; 19118102; 19120486; 19124725; 19131814; 19134118; 19135114; 19140875; 19148143; 19148938; 19150884; 19159017; 19164128; 19181857; 19189651; 19191896; 19195606; 19200604; 19201903; 19215923; 19218437; 19238444; 19239434; 19247692; 19252480; 19254290; 19258923; 19264973; 19265114; 19265483; 19267370; 19275590; 19277200; 19280717; 19289835; 19295440; 19306954; 19317913; 19318560; 19321453; 19336370; 19336475; 19351596; 19368968; 19376887; 19380025; 19390489; 19395279; 19395541; 19398177; 19405031; 19407153; 19412184; 19412702; 19422935; 19423540; 19426173; 19430824; 19436306; 19445369; 19445990; 19447045; 19453261; 19455302; 19473079; 19483297; 19493410; 19494321; 19494325; 19496069; 19500628; 19502387; 19505919; 19509286; 19513622; 19522765; 19527514; 19528164; 19528814; 19531762; 19539691; 19541348; 19542021; 19543401; 19545686; 19546479; 19548630; 19554026; 19556306; 19556696; 19561617; 19564644; 19564704; 19566553; 19572373; 19573080; 19575238; 19578796; 19584052; 19586676; 19590686; 19592497; 19593445; 19596916; 19597734; 19614650; 19622038; 19627277; 19628747; 19631641; 19638314; 19643479; 19646345; 19646728; 19656901; 19660727; 19664207; 19691982; 19692168; 19706440; 19710105; 19723394; 19729601; 19730000; 19735472; 19737468; 19740627; 19741468; 19750015; 19754671; 19758312; 19760027; 19763595; 19764566; 19769961; 19771452; 19772581; 19773279; 19773677; 19779605; 19796532; 19796535; 19796680; 19809335; 19809507; 19810822; 19811440; 19816595; 19824106; 19826413; 19839752; 19840833; 19841637; 19844258; 19844589; 19846529; 19846881; 19847953; 19855253; 19858308; 19888805; 19891659; 19892918; 19902255; 19912257; 19913121; 19913922; 19915052; 19922963; 19924287; 19928913; 19929430; 19948740; 19948975; 19953283; 19956541; 19956717; 19960069; 20001205; 20002809; 20007708; 20007974; 20011079; 20011698; 20016852; 20018893; 20026833; 20026892; 20030948; 20037584; 20039305; 20047764; 20048342; 20056178; 20059631; 20063104; 20067961; 20067962; 20078877; 20079790; 20083228; 20085599; 20092898; 20093834; 20098705; 20105294; 20109750; 20120936; 20124101; 20125114; 20140262; 20145198; 20145615; 20146922; 20153491; 20164024; 20169003; 20170964; 20177675; 20179247; 20187300; 20194452; 20196781; 20197549; 20200442; 20201793; 20207250; 20212095; 20214986; 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23455702; 23457721; 23460645; 23465595; 23467413; 23470644; 23497941; 23504385; 23510418; 23525077; 23554896; 23555011; 23565226; 23574398; 23589304; 23592020; 23592986; 23611610; 23612767; 23629657; 23633568; 23639307; 23651260; 23665674; 23671673; 23673286; 23677465; 23678609; 23680697; 23690937; 23691015; 23692033; 23727604; 23738004; 23747880; 23752129; 23755898; 23761639; 23766695; 23786414; 23798430; 23799413; 23802631; 23821954; 23828139; 23836485; 23853092; 23855294; 23864765; 23871732; 23879541; 23880187; 23888080; 23888605; 23908180; 23910802; 23921128; 23936050; 23936790; 23949880; 23962979; 23980810; 23985798; 24021278; 24030146; 24044965; 24068665; 24076166; 24080332; 24084649; 24106112; 24172224; 24178299; 24277938; 24298017; 24307174 toll-like receptor 4 Ensembl:ENSG00000136869 HGNC:11850 HPRD:04325 MIM:603030 Vega:OTTHUMG00000021046 TLR4 Bin Zhao, Yue Liu, Oliver He DIF TNF-alpha TNFA TNFSF2 WEB: http://www.ncbi.nlm.nih.gov/gene TNF tumor necrosis factor 7124 DADB-70P7.1 6p21.3 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000060 (EC: IDA, PMID: 16280327); GO_0000122 (EC: IDA, PMID: 15345745); GO_0000165 (EC: IMP); GO_0000185 (EC: IDA, PMID: 15310755); GO_0000187 (EC: IDA, PMID: 10748004); GO_0001666 (EC: IEA); GO_0001775 (EC: IEA); GO_0001819 (EC: IDA, PMID: 17922812); GO_0001891 (EC: ISS); GO_0001934 (EC: IDA, PMID: 10748004); GO_0002020 (EC: IPI, PMID: 12777399); GO_0002037 (EC: IEA); GO_0002439 (EC: IMP, PMID: 14512626); GO_0002740 (EC: IDA, PMID: 10443688); GO_0002876 (EC: IEA); GO_0002925 (EC: IEA); GO_0003009 (EC: IEA); GO_0005125 (EC: IDA, PMID: 10748004); GO_0005164 (EC: IDA, PMID: 14512626); GO_0005515 (EC: IPI, PMID: 11878931); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 10443688); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 18355445); GO_0006006 (EC: IEA); GO_0006915 (EC: TAS); GO_0006919 (EC: IDA, PMID: 16723520); GO_0006927 (EC: IDA, PMID: 3883195); GO_0006954 (EC: IDA, PMID: 10748004); GO_0006959 (EC: IEA); GO_0007254 (EC: IEA); GO_0008285 (EC: IEA); GO_0008625 (EC: IDA, PMID: 10521396); GO_0008625 (EC: NAS); GO_0008630 (EC: IEA); GO_0008652 (EC: IEA); GO_0009612 (EC: IEA); GO_0009615 (EC: IDA, PMID: 10490959); GO_0009651 (EC: TAS, PMID: 18355445); GO_0009887 (EC: IEA); GO_0009897 (EC: ISS); GO_0009986 (EC: IDA, PMID: 18355445); GO_0010629 (EC: IDA, PMID: 15345745); GO_0010693 (EC: IEA); GO_0010888 (EC: NAS, PMID: 16464856); GO_0014823 (EC: IEA); GO_0019722 (EC: IEA); GO_0030198 (EC: IEA); GO_0030316 (EC: IEA); GO_0030730 (EC: IDA, PMID: 19032770); GO_0031334 (EC: IDA, PMID: 12813029); GO_0031622 (EC: ISS); GO_0031663 (EC: IDA); GO_0032715 (EC: IDA, PMID: 10443688); GO_0032722 (EC: IDA, PMID: 10490959); GO_0032729 (EC: IEA); GO_0032741 (EC: IEA); GO_0032755 (EC: IEA); GO_0032800 (EC: IDA, PMID: 10443688); GO_0033138 (EC: IDA, PMID: 17389591); GO_0033209 (EC: IMP, PMID: 10748004); GO_0034116 (EC: IDA, PMID: 10604883); GO_0042346 (EC: IDA, PMID: 17922812); GO_0042493 (EC: IEA); GO_0042802 (EC: IDA, PMID: 14512626); GO_0043065 (EC: IDA, PMID: 16723520); GO_0043068 (EC: IDA, PMID: 16611992); GO_0043122 (EC: IDA, PMID: 10748004); GO_0043123 (EC: IDA, PMID: 15310755); GO_0043242 (EC: IDA, PMID: 17389591); GO_0043243 (EC: IDA, PMID: 12813029); GO_0043280 (EC: IDA, PMID: 11577081); GO_0043406 (EC: IDA, PMID: 12813029); GO_0043491 (EC: IMP); GO_0043507 (EC: IDA, PMID: 17389591); GO_0043525 (EC: IEA); GO_0044130 (EC: IEA); GO_0044212 (EC: IDA, PMID: 17350185); GO_0045071 (EC: IDA, PMID: 10490959); GO_0045080 (EC: IDA, PMID: 10490959); GO_0045121 (EC: IDA, PMID: 17010968); GO_0045416 (EC: IDA); GO_0045429 (EC: IDA, PMID: 8383325); GO_0045599 (EC: NAS, PMID: 16464856); GO_0045668 (EC: IEA); GO_0045672 (EC: IDA, PMID: 17888176); GO_0045840 (EC: IEA); GO_0045892 (EC: IDA, PMID: 16895791); GO_0045893 (EC: IDA, PMID: 10748004); GO_0045944 (EC: IDA, PMID: 15345745); GO_0045944 (EC: IGI, PMID: 16803872); GO_0045994 (EC: IEA); GO_0046325 (EC: IEA); GO_0046330 (EC: IEA); GO_0048566 (EC: IEP); GO_0048661 (EC: IDA, PMID: 16518841); GO_0050715 (EC: IDA, PMID: 10443688); GO_0050796 (EC: IDA, PMID: 8383325); GO_0050806 (EC: IEA); GO_0050830 (EC: IEA); GO_0050901 (EC: IDA, PMID: 10820279); GO_0050995 (EC: IDA, PMID: 19032770); GO_0051023 (EC: IEA); GO_0051044 (EC: IDA, PMID: 18373975); GO_0051091 (EC: IDA, PMID: 10748004); GO_0051092 (EC: IDA, PMID: 10383454); GO_0051222 (EC: IDA, PMID: 15310755); GO_0051384 (EC: IDA, PMID: 10443688); GO_0051533 (EC: IDA, PMID: 16803872); GO_0051798 (EC: IEA); GO_0051897 (EC: IEA); GO_0055037 (EC: ISS); GO_0060557 (EC: IDA, PMID: 1690216); GO_0060559 (EC: IDA, PMID: 1690216); GO_0060664 (EC: IEA); GO_0060693 (EC: IEA); GO_0061048 (EC: IDA, PMID: 17350185); GO_0070374 (EC: NAS, PMID: 18606301); GO_0071230 (EC: IEA); GO_0071316 (EC: IDA, PMID: 18676776); GO_0071407 (EC: IDA); GO_0071677 (EC: NAS); GO_0071803 (EC: IDA, PMID: 15220135); GO_0097190 (EC: TAS); GO_0097191 (EC: IDA, PMID: 11577081); GO_0097527 (EC: IDA, PMID: 11101870); GO_1902043 (EC: IEA); GO_2000010 (EC: IDA, PMID: 19366699); GO_2000343 (EC: IDA); GO_2001240 (EC: IDA, PMID: 10666185) PMID: 1279199; 1310388; 1331108; 1380260; 1402651; 1548758; 1550865; 1690216; 1905933; 1918997; 1918999; 1964681; 1993354; 2009860; 2158863; 2170559; 2413547; 2537468; 2551905; 2848815; 2922050; 2995927; 3001529; 3031624; 3139842; 3351931; 3417634; 3464978; 3552045; 3555974; 3856324; 3883195; 3932069; 6392892; 7494249; 7511078; 7523444; 7526541; 7536422; 7561697; 7664431; 7693046; 7695626; 7704970; 7706435; 7739525; 7758105; 7815507; 7818827; 7852363; 7859743; 7930591; 7935762; 7966397; 8182064; 8267288; 8288897; 8336080; 8336118; 8381971; 8383325; 8482849; 8499947; 8590321; 8597870; 8707350; 8724035; 8764000; 8806809; 8852605; 8869635; 8870842; 9034191; 9108403; 9110146; 9223523; 9225992; 9226228; 9230816; 9269771; 9269777; 9278385; 9334723; 9344703; 9378998; 9438495; 9442056; 9449720; 9488135; 9552007; 9568681; 9639071; 9651389; 9658081; 9670843; 9730685; 9744279; 9828130; 9920899; 10202016; 10205166; 10339575; 10369255; 10376933; 10383454; 10388525; 10415019; 10438928; 10443688; 10450718; 10490959; 10521396; 10604883; 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22884017; 22884417; 22884981; 22891927; 22897390; 22897480; 22898217; 22902304; 22903530; 22905199; 22913362; 22917968; 22918199; 22921153; 22921402; 22922291; 22922824; 22923002; 22927431; 22937208; 22937788; 22940143; 22944040; 22945416; 22947142; 22947907; 22948157; 22949029; 22950839; 22960943; 22964479; 22982041; 22983646; 22984233; 22986484; 22986613; 22986753; 22990108; 22990365; 22990627; 22992806; 22995913; 22999526; 23009757; 23011034; 23013131; 23021488; 23028059; 23028877; 23029405; 23032186; 23032187; 23033000; 23034253; 23036097; 23046723; 23050663; 23057546; 23058031; 23065208; 23066418; 23067363; 23068962; 23069299; 23070544; 23071313; 23073259; 23077985; 23079033; 23081800; 23082052; 23086255; 23089051; 23092582; 23092711; 23096596; 23100065; 23100272; 23103767; 23110185; 23122308; 23137321; 23139429; 23141142; 23142559; 23159355; 23159874; 23164102; 23167810; 23168096; 23169178; 23176610; 23179933; 23183825; 23192010; 23193891; 23195574; 23204162; 23209346; 23209731; 23212700; 23217179; 23225254; 23229544; 23233369; 23246833; 23249640; 23254337; 23255681; 23258148; 23258237; 23265967; 23275336; 23276701; 23280137; 23281720; 23284977; 23288922; 23290099; 23294492; 23294973; 23294975; 23297421; 23298660; 23300810; 23305356; 23313255; 23315809; 23317256; 23317877; 23322904; 23326309; 23326472; 23327497; 23328497; 23331923; 23333028; 23333893; 23333920; 23334278; 23335080; 23338599; 23339186; 23343370; 23349048; 23349093; 23349721; 23357300; 23359411; 23359428; 23359489; 23363891; 23376082; 23377880; 23378732; 23380141; 23388693; 23393163; 23394901; 23396208; 23403273; 23406059; 23413901; 23425028; 23432860; 23437179; 23451177; 23459075; 23462597; 23465534; 23466425; 23470607; 23472126; 23484124; 23484152; 23485383; 23485538; 23487197; 23489698; 23494178; 23498057; 23500081; 23500159; 23503445; 23507260; 23527193; 23527710; 23532748; 23542051; 23546865; 23550407; 23552949; 23553861; 23555579; 23557460; 23559847; 23567762; 23576453; 23577187; 23581259; 23588423; 23590297; 23592910; 23593411; 23593415; 23594457; 23597429; 23601741; 23602201; 23607333; 23615914; 23619127; 23625043; 23630220; 23630362; 23632060; 23634661; 23638863; 23639307; 23639700; 23640160; 23643268; 23651237; 23651848; 23657597; 23657600; 23658704; 23661556; 23661584; 23663047; 23669395; 23673311; 23677169; 23680697; 23682387; 23683942; 23703343; 23704210; 23712703; 23713409; 23717605; 23720844; 23723980; 23732752; 23732909; 23740956; 23745338; 23746176; 23746843; 23748363; 23751348; 23768164; 23774701; 23777202; 23785756; 23785788; 23793505; 23795660; 23800059; 23816715; 23821300; 23828749; 23834030; 23861398; 23864804; 23870134; 23877857; 23880295; 23884763; 23900678; 23911749; 23918043; 23923372; 23925283; 23935096; 23936398; 23936458; 23940760; 23943369; 23943614; 23965971; 23989985; 24012198; 24018067; 24041577; 24049437; 24067962; 24077340; 24078775; 24140406; 24145654; 24186266; 24265545; 24294778; 24299316; 24307062; 24307172; 24313836; 24314919; 24316671; 24338609; 24340926; 24371310; 24403490; 24409675; 24459820; 24611333; 24611335 tumor necrosis factor Ensembl:ENSG00000232810 HGNC:11892 HPRD:01855 MIM:191160 Vega:OTTHUMG00000031194 TNF Bin Zhao, Yue Liu, Oliver He B94 EXOC3L3 WEB: http://www.ncbi.nlm.nih.gov/gene TNFAIP2 tumor necrosis factor, alpha-induced protein 2 7127 14q32 20140408 9606 14 protein-coding Official from a nomenclature committee GO_0000145 (EC: IEA); GO_0001525 (EC: IEA); GO_0005615 (EC: TAS, PMID: 1374453); GO_0006887 (EC: IEA); GO_0030154 (EC: IEA) PMID: 1374453; 8106408; 10766166; 12477932; 19339270; 19913121; 20157331; 20237496; 20628086; 20628624; 21057457; 21139048; 21399635; 21555518; 21921781; 21934093; 22797925; 22939629; 23438482; 23724109 tumor necrosis factor, alpha-induced protein 2 Ensembl:ENSG00000185215 HGNC:11895 HPRD:04487 MIM:603300 Vega:OTTHUMG00000171890 TNFAIP2 Bin Zhao, Yue Liu, Oliver He CD120a FPF MS5 TBP1 TNF-R TNF-R-I TNF-R55 TNFAR TNFR1 TNFR1-d2 TNFR55 TNFR60 p55 p55-R p60 WEB: http://www.ncbi.nlm.nih.gov/gene TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 7132 12p13.2 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000139 (EC: IDA); GO_0001666 (EC: IEA); GO_0002020 (EC: IEA); GO_0005031 (EC: TAS, PMID: 2158863); GO_0005515 (EC: IPI, PMID: 10848577); GO_0005576 (EC: NAS, PMID: 12189246); GO_0005615 (EC: IDA, PMID: 13130484); GO_0005634 (EC: IEA); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 1698610); GO_0006693 (EC: IEA); GO_0006915 (EC: TAS); GO_0006954 (EC: ISS); GO_0008625 (EC: TAS, PMID: 8612133); GO_0008630 (EC: IEA); GO_0009986 (EC: IEA); GO_0010629 (EC: IEA); GO_0016032 (EC: IEA); GO_0019221 (EC: ISS); GO_0030424 (EC: IEA); GO_0032403 (EC: IEA); GO_0032496 (EC: IEA); GO_0032715 (EC: IEA); GO_0032760 (EC: IEA); GO_0033013 (EC: IEA); GO_0033160 (EC: IEA); GO_0042511 (EC: IMP); GO_0042742 (EC: IEA); GO_0043066 (EC: IEA); GO_0043120 (EC: IEA); GO_0043123 (EC: IEP, PMID: 12761501); GO_0043200 (EC: IEA); GO_0043235 (EC: IDA); GO_0043279 (EC: IEA); GO_0045121 (EC: IDA, PMID: 17010968); GO_0045471 (EC: IEA); GO_0045766 (EC: IEA); GO_0045944 (EC: IMP); GO_0045944 (EC: ISS); GO_0050728 (EC: IMP, PMID: 13130484); GO_0050729 (EC: ISS); GO_0051291 (EC: IEA); GO_0071260 (EC: IEP, PMID: 19593445); GO_0071392 (EC: IEA); GO_0097190 (EC: TAS) PMID: 1087798; 1310388; 1315717; 1331108; 1648547; 1655358; 1698610; 1702293; 2153136; 2158862; 2158863; 2170559; 2170974; 2848815; 3001529; 7156325; 7601280; 7664431; 7758105; 7852363; 7859281; 7876093; 7901149; 7995952; 8077196; 8182064; 8288897; 8387891; 8565075; 8612133; 8621670; 8808629; 8906799; 8934525; 8939750; 8943045; 8985253; 9038203; 9045686; 9082980; 9115275; 9126987; 9215629; 9237663; 9510175; 9557650; 9560245; 9563508; 9568681; 9585614; 9642260; 9753329; 9915703; 10187798; 10187805; 10199409; 10339433; 10356400; 10359574; 10400625; 10634209; 10706119; 10755617; 10848577; 10875917; 10902757; 10911999; 11002417; 11002422; 11035039; 11072751; 11078718; 11098060; 11163081; 11175303; 11196686; 11212177; 11226577; 11443543; 11522182; 11528523; 11562425; 11598334; 11606045; 11676596; 11684708; 11737221; 11755217; 11786908; 11801527; 11821416; 11861282; 11882518; 11904678; 11909948; 11920568; 11934887; 11937569; 11947900; 11961180; 11985495; 12017295; 12040173; 12049175; 12082592; 12105243; 12107724; 12115625; 12147741; 12189246; 12209507; 12209523; 12220546; 12353079; 12376300; 12391233; 12477932; 12500222; 12530121; 12559634; 12601524; 12610052; 12644782; 12651071; 12661999; 12690082; 12706861; 12730509; 12748169; 12748171; 12753742; 12761501; 12768019; 12786601; 12811828; 12818408; 12832748; 12858434; 12879482; 12887914; 12887920; 12911633; 12913922; 13130484; 14585990; 14610673; 14671137; 14694358; 14702039; 14728878; 14743216; 14872483; 15018649; 15041705; 15063762; 15071491; 15146559; 15188372; 15247912; 15251454; 15274667; 15288471; 15289829; 15301860; 15310755; 15457442; 15465831; 15485837; 15489334; 15492850; 15502938; 15526005; 15542843; 15586174; 15659383; 15692984; 15707590; 15743837; 15787661; 15817701; 15818692; 15842589; 15851552; 15943902; 15949439; 16043718; 16043808; 16115877; 16134057; 16142859; 16153798; 16195372; 16216134; 16227624; 16234278; 16260783; 16277675; 16282562; 16289162; 16291755; 16344560; 16447098; 16463024; 16533817; 16580225; 16611992; 16680093; 16731080; 16732051; 16859822; 16968706; 17010968; 17051333; 17075277; 17105909; 17200772; 17234651; 17267158; 17324927; 17346438; 17431682; 17477815; 17530646; 17564788; 17665435; 17665448; 17686637; 17688691; 17693606; 17703412; 17763205; 17785864; 17852084; 17921876; 18022363; 18037881; 18058462; 18067272; 18068948; 18078813; 18083240; 18086728; 18163488; 18167350; 18174230; 18180277; 18206417; 18243134; 18248655; 18275007; 18287568; 18333356; 18337349; 18338763; 18408954; 18415772; 18445477; 18508832; 18510047; 18512793; 18538149; 18541194; 18544535; 18571427; 18606683; 18621737; 18625701; 18676680; 18679053; 18715339; 18717726; 18724939; 18776134; 18807256; 18818748; 18936101; 18939944; 18949366; 18990758; 19019335; 19029521; 19070941; 19077906; 19084540; 19116900; 19170196; 19193342; 19238748; 19242924; 19246939; 19258923; 19287455; 19289468; 19322201; 19336370; 19339767; 19369902; 19390513; 19390575; 19448410; 19453261; 19505916; 19523687; 19524513; 19525953; 19527514; 19541728; 19556827; 19579027; 19582456; 19593445; 19594495; 19625176; 19641466; 19643942; 19673872; 19690440; 19692168; 19692652; 19701605; 19738620; 19741298; 19772798; 19773279; 19773432; 19773451; 19784808; 19789190; 19794511; 19796978; 19801788; 19804406; 19815541; 19825522; 19826638; 19845893; 19854717; 19865102; 19879194; 19879354; 19890662; 19892918; 19906316; 19913121; 19948975; 20045350; 20062090; 20066156; 20074459; 20074469; 20098615; 20100586; 20110607; 20237496; 20331378; 20333651; 20371430; 20400394; 20421368; 20422457; 20430450; 20430728; 20446090; 20448643; 20452482; 20453000; 20457915; 20458742; 20483718; 20497634; 20503287; 20506103; 20511226; 20516030; 20532935; 20564232; 20566746; 20568250; 20602615; 20628086; 20635912; 20646338; 20654748; 20673868; 20695192; 20811626; 20825417; 20930310; 20955203; 20980627; 21029567; 21037509; 21048031; 21068102; 21113135; 21113948; 21124859; 21132303; 21153350; 21153367; 21153368; 21225694; 21256825; 21284530; 21288590; 21315128; 21316985; 21321109; 21331078; 21350240; 21385537; 21393509; 21399635; 21418516; 21420073; 21523796; 21552549; 21555518; 21565411; 21567205; 21602493; 21724995; 21737329; 21789618; 21813053; 21819445; 21833088; 21850048; 21880774; 21920667; 21930713; 21963094; 21976655; 21988832; 22036455; 22042131; 22059991; 22099304; 22115362; 22179575; 22209080; 22215119; 22228740; 22235167; 22272576; 22281876; 22288185; 22297296; 22311714; 22343913; 22396498; 22535754; 22547679; 22568977; 22609894; 22617158; 22675546; 22733818; 22749881; 22801493; 22848449; 22860894; 22945416; 22994200; 23000965; 23019260; 23032187; 23081800; 23082052; 23086255; 23117241; 23160117; 23205868; 23207486; 23269568; 23316846; 23321203; 23322460; 23322903; 23360651; 23405158; 23461592; 23490134; 23493346; 23494522; 23505244; 23526964; 23532748; 23619127; 23620528; 23624563; 23648065; 23745996; 23746843; 23894535; 24130170; 24174586 tumor necrosis factor receptor superfamily, member 1A Ensembl:ENSG00000067182 HGNC:11916 HPRD:01861 MIM:191190 Vega:OTTHUMG00000168267 TNFRSF1A Bin Zhao, Yue Liu, Oliver He BCC7 LFS1 P53 TRP53 WEB: http://www.ncbi.nlm.nih.gov/gene TP53 tumor protein p53 7157 17p13.1 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000060 (EC: IEA); GO_0000122 (EC: IBA); GO_0000122 (EC: IDA, PMID: 15340061); GO_0000122 (EC: ISS, PMID: 19749791); GO_0000733 (EC: IDA, PMID: 8183576); GO_0000785 (EC: IBA); GO_0000790 (EC: IDA, PMID: 15710329); GO_0000979 (EC: IEA); GO_0001077 (EC: IEA); GO_0001085 (EC: IPI, PMID: 18549481); GO_0001228 (EC: IDA, PMID: 17146433); GO_0001701 (EC: IEA); GO_0001756 (EC: IEA); GO_0001836 (EC: IEA); GO_0002020 (EC: IPI, PMID: 11923872); GO_0002039 (EC: IBA); GO_0002309 (EC: IEA); GO_0002326 (EC: IEA); GO_0002360 (EC: IEA); GO_0002931 (EC: IEA); GO_0003677 (EC: IMP, PMID: 2144364); GO_0003682 (EC: IDA, PMID: 16322561); GO_0003684 (EC: IBA); GO_0003700 (EC: IDA, PMID: 18549481); GO_0005507 (EC: IDA, PMID: 7824276); GO_0005515 (EC: IPI, PMID: 10196247); GO_0005524 (EC: IDA, PMID: 8183576); GO_0005634 (EC: IDA); GO_0005654 (EC: IDA, PMID: 11080164); GO_0005654 (EC: TAS); GO_0005657 (EC: IBA); GO_0005669 (EC: IDA, Qualifier: colocalizes_with, PMID: 15053879); GO_0005730 (EC: IDA, PMID: 12080348); GO_0005737 (EC: IDA, PMID: 14744935); GO_0005739 (EC: IDA, PMID: 12667443); GO_0005759 (EC: IEA); GO_0005783 (EC: IEA); GO_0005829 (EC: IBA); GO_0005829 (EC: IDA, PMID: 14963330); GO_0006284 (EC: TAS, PMID: 15116721); GO_0006289 (EC: IMP, PMID: 7663514); GO_0006302 (EC: IEA); GO_0006355 (EC: IDA, PMID: 7587074); GO_0006461 (EC: IDA, PMID: 12915590); GO_0006915 (EC: TAS); GO_0006974 (EC: IDA, PMID: 14744935); GO_0006977 (EC: TAS); GO_0006978 (EC: IMP, PMID: 7958916); GO_0006983 (EC: IDA, PMID: 14744935); GO_0007050 (EC: IDA, PMID: 15149599); GO_0007050 (EC: IMP, PMID: 10962037); GO_0007179 (EC: IEA); GO_0007219 (EC: TAS); GO_0007265 (EC: IEP, PMID: 9054499); GO_0007275 (EC: IMP, PMID: 10065150); GO_0007369 (EC: IEA); GO_0007406 (EC: IEA); GO_0007417 (EC: IEA); GO_0007569 (EC: IMP, PMID: 12080348); GO_0007596 (EC: TAS); GO_0008104 (EC: IDA, PMID: 16507995); GO_0008134 (EC: IPI, PMID: 15053879); GO_0008156 (EC: IEA); GO_0008270 (EC: TAS, PMID: 10065153); GO_0008283 (EC: TAS, PMID: 10065150); GO_0008285 (EC: ISS); GO_0008340 (EC: ISS); GO_0009303 (EC: IEA); GO_0009651 (EC: IEA); GO_0010165 (EC: IBA); GO_0010332 (EC: IMP, PMID: 7958916); GO_0010666 (EC: IEA); GO_0016032 (EC: IEA); GO_0016363 (EC: IDA, PMID: 11080164); GO_0016604 (EC: IDA, Qualifier: colocalizes_with, PMID: 10360174); GO_0016605 (EC: IDA, PMID: 12006491); GO_0019899 (EC: IPI, PMID: 10666337); GO_0019901 (EC: IPI, PMID: 11546806); GO_0019903 (EC: IPI); GO_0030154 (EC: TAS, PMID: 10065150); GO_0030308 (EC: IMP, PMID: 8986812); GO_0030330 (EC: IDA, PMID: 15149599); GO_0030330 (EC: IMP); GO_0030512 (EC: IEA); GO_0030971 (EC: IPI); GO_0031065 (EC: IBA); GO_0031497 (EC: IDA, PMID: 16322561); GO_0031571 (EC: IMP, PMID: 7958916); GO_0031625 (EC: IPI, PMID: 10415337); GO_0032461 (EC: IDA, PMID: 12667443); GO_0033077 (EC: IEA); GO_0034103 (EC: IEA); GO_0034613 (EC: IDA, PMID: 15340061); GO_0034644 (EC: IBA); GO_0035033 (EC: IEA); GO_0035035 (EC: IPI, PMID: 10518217); GO_0035264 (EC: IEA); GO_0035690 (EC: IEP); GO_0042149 (EC: IDA, PMID: 14744935); GO_0042771 (EC: IDA, PMID: 14654789); GO_0042802 (EC: IPI, PMID: 16291740); GO_0042981 (EC: IDA, PMID: 14744935); GO_0043065 (EC: IDA, PMID: 12667443); GO_0043066 (EC: IDA, PMID: 16131611); GO_0043066 (EC: IEA); GO_0043234 (EC: IDA, PMID: 9529249); GO_0043525 (EC: IBA); GO_0044212 (EC: IDA, PMID: 15710329); GO_0045892 (EC: ISS, PMID: 19749791); GO_0045893 (EC: IDA, PMID: 16322561); GO_0045893 (EC: IMP); GO_0045944 (EC: IDA, PMID: 11672523); GO_0045944 (EC: IGI, PMID: 16061649); GO_0045944 (EC: IMP, PMID: 17146433); GO_0046677 (EC: IEP); GO_0046902 (EC: TAS, PMID: 15116721); GO_0046982 (EC: IPI, PMID: 10837489); GO_0047485 (EC: IPI, PMID: 11861836); GO_0048147 (EC: IMP, PMID: 10962037); GO_0048568 (EC: IEA); GO_0050731 (EC: ISS, PMID: 19749791); GO_0051087 (EC: IPI, PMID: 18086682); GO_0051097 (EC: TAS, PMID: 7663514); GO_0051262 (EC: TAS, PMID: 15116721); GO_0051402 (EC: IEA); GO_0051721 (EC: IPI, PMID: 17245430); GO_0070245 (EC: ISS); GO_0071158 (EC: IMP); GO_0071456 (EC: IEP); GO_0071479 (EC: IMP); GO_0071850 (EC: IEA); GO_0072332 (EC: IMP, PMID: 12172011); GO_0090200 (EC: IDA, PMID: 12667443); GO_0090343 (EC: IEA); GO_0090399 (EC: IMP, PMID: 19951988); GO_0090403 (EC: IMP, PMID: 19951988); GO_0097193 (EC: TAS, PMID: 16462759); GO_0097252 (EC: IDA, PMID: 7720704); GO_0097371 (EC: IEA); GO_1900740 (EC: TAS); GO_1901525 (EC: IEA); GO_1902108 (EC: IEA); GO_2000378 (EC: IEA); GO_2000379 (EC: IMP); GO_2001244 (EC: IMP, PMID: 14963330) PMID: 1088347; 1303181; 1327751; 1349102; 1349175; 1394225; 1437144; 1454855; 1459726; 1465435; 1565143; 1565144; 1591732; 1600943; 1631137; 1631151; 1644930; 1647768; 1672732; 1673792; 1679237; 1683921; 1694291; 1699228; 1705009; 1737852; 1762941; 1848668; 1849234; 1868473; 1905840; 1915267; 1933902; 1939648; 1978757; 1999338; 2047879; 2141171; 2144364; 2156209; 2259385; 2263646; 2531845; 2839831; 2905688; 2946935; 2994241; 3001719; 3025664; 3456488; 3894933; 4006916; 6396087; 7587074; 7663514; 7682763; 7686617; 7720704; 7753047; 7761466; 7773777; 7777531; 7799929; 7809597; 7811761; 7818536; 7824276; 7853525; 7878469; 7887414; 7935417; 7935455; 7958916; 8013454; 8016121; 8023157; 8023159; 8028670; 8058315; 8090726; 8118819; 8125298; 8134127; 8183576; 8207805; 8221626; 8266092; 8316628; 8336944; 8361542; 8364550; 8380895; 8389468; 8401536; 8402617; 8423216; 8463313; 8513440; 8612585; 8617246; 8619474; 8623534; 8623910; 8632903; 8632915; 8639538; 8649785; 8668206; 8675009; 8729618; 8816502; 8825920; 8829627; 8829653; 8875926; 8875929; 8895579; 8921390; 8940078; 8943363; 8961277; 8986812; 9010216; 9054499; 9101296; 9110174; 9119221; 9129988; 9135004; 9143503; 9183006; 9194564; 9194565; 9215863; 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23793604; 23794094; 23796514; 23796712; 23799027; 23799104; 23800173; 23800953; 23802716; 23804139; 23811687; 23812725; 23812727; 23817390; 23818345; 23818355; 23818364; 23826318; 23835407; 23835706; 23836507; 23837945; 23841076; 23844043; 23844254; 23845906; 23851436; 23852341; 23860773; 23863845; 23870121; 23870475; 23873310; 23878395; 23880211; 23880345; 23880760; 23881403; 23886144; 23894400; 23896410; 23907539; 23908595; 23908596; 23915071; 23916609; 23918540; 23933584; 23935506; 23936455; 23942113; 23946421; 23954287; 23954291; 23954467; 23959174; 23959540; 23960076; 23962557; 23965232; 23966169; 23966171; 23966406; 23966881; 23967302; 23971040; 23973262; 23973461; 23977882; 23981578; 23982177; 23990016; 23991992; 23994832; 24001612; 24003224; 24006363; 24006461; 24008423; 24012673; 24014029; 24022481; 24023291; 24023325; 24025248; 24026986; 24029231; 24032713; 24038938; 24042100; 24043769; 24044511; 24045667; 24046089; 24052075; 24053468; 24056649; 24061453; 24067370; 24067899; 24067978; 24074410; 24076372; 24078252; 24091621; 24099634; 24101517; 24113167; 24113472; 24120139; 24122997; 24129246; 24134839; 24143256; 24145651; 24163369; 24164297; 24183724; 24190973; 24200963; 24209622; 24219989; 24220032; 24231352; 24239288; 24240685; 24241536; 24248600; 24256616; 24272483; 24285725; 24289924; 24314634; 24316591; 24323028; 24344030; 24361594; 24379070; 24379358; 24403473; 24434386; 24449575; 24617039 tumor protein p53 Ensembl:ENSG00000141510 HGNC:11998 HPRD:01859 MIM:191170 Vega:OTTHUMG00000162125 TP53 Bin Zhao, Yue Liu, Oliver He MGC:45012 TRAP TRAP3 WEB: http://www.ncbi.nlm.nih.gov/gene TRAF2 TNF receptor-associated factor 2 7186 9q34 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0002726 (EC: IMP, PMID: 15125833); GO_0004842 (EC: IDA, PMID: 15258597); GO_0004871 (EC: NAS, PMID: 8702708); GO_0005164 (EC: IPI, PMID: 11279055); GO_0005174 (EC: ISS); GO_0005515 (EC: IPI, PMID: 10514511); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0005938 (EC: IEA); GO_0006461 (EC: TAS, PMID: 8702708); GO_0006915 (EC: TAS); GO_0006919 (EC: TAS); GO_0007165 (EC: TAS, PMID: 8702708); GO_0007250 (EC: IMP, PMID: 15125833); GO_0008270 (EC: IEA); GO_0009898 (EC: ISS); GO_0019899 (EC: IPI, PMID: 16636664); GO_0019903 (EC: IPI, PMID: 15696169); GO_0030163 (EC: IEA); GO_0031435 (EC: IEA); GO_0031625 (EC: IPI, PMID: 11279055); GO_0031996 (EC: IPI, PMID: 11279055); GO_0032403 (EC: IEA); GO_0032743 (EC: IMP, PMID: 15125833); GO_0033209 (EC: IDA, PMID: 11907583); GO_0034351 (EC: IEA); GO_0035631 (EC: ISS); GO_0042802 (EC: IPI, PMID: 16189514); GO_0042981 (EC: IDA, PMID: 11907583); GO_0043507 (EC: IDA, PMID: 11907583); GO_0043623 (EC: ISS); GO_0045087 (EC: TAS); GO_0045121 (EC: IEA); GO_0046625 (EC: IDA); GO_0050870 (EC: IC, PMID: 15125833); GO_0051023 (EC: IEA); GO_0051091 (EC: IMP, PMID: 12296995); GO_0051092 (EC: IDA, PMID: 11279055); GO_0051092 (EC: IMP, PMID: 12296995); GO_0051291 (EC: IEA); GO_0051865 (EC: IDA); GO_0051865 (EC: TAS, PMID: 16378096); GO_0070207 (EC: IPI); GO_0070534 (EC: IDA, PMID: 15258597); GO_0090073 (EC: IMP, PMID: 11278723); GO_0097190 (EC: TAS); GO_2001238 (EC: IMP); GO_2001239 (EC: TAS) PMID: 7639698; 7758105; 8069916; 8125298; 8548810; 8565075; 8612133; 8627180; 8643514; 8662842; 8692885; 8702708; 8710854; 8875942; 8943045; 8985011; 8999898; 9020361; 9104814; 9153189; 9162022; 9168896; 9208847; 9244310; 9275204; 9353251; 9384571; 9418902; 9461607; 9464265; 9488716; 9500555; 9582383; 9607925; 9685412; 9692890; 9705938; 9712898; 9718306; 9733516; 9774460; 9774977; 9794406; 9827693; 9852070; 9990007; 10025951; 10037686; 10075662; 10206649; 10339433; 10346818; 10352240; 10411888; 10477597; 10490605; 10514511; 10521462; 10523862; 10544141; 10581243; 10617615; 10650002; 10753917; 10759890; 10764746; 10809768; 10837247; 10880535; 10882101; 10892748; 10903733; 10911999; 10980203; 10990461; 11035039; 11057907; 11064452; 11112773; 11181075; 11278268; 11278723; 11279055; 11340079; 11359906; 11384837; 11435475; 11466612; 11479302; 11562359; 11607847; 11728344; 11777919; 11784851; 11798190; 11804591; 11805080; 11821416; 11882293; 11907088; 11907583; 11909853; 11932422; 11971184; 12005438; 12136106; 12169272; 12220533; 12296995; 12411322; 12411493; 12477932; 12529173; 12547194; 12571250; 12591926; 12637493; 12796506; 12842894; 12843613; 12867425; 12887920; 12917689; 12917690; 12917691; 14517219; 14557256; 14585990; 14633987; 14644197; 14702039; 14741690; 14743216; 14982987; 15084608; 15121867; 15125833; 15208311; 15258597; 15265700; 15308666; 15310755; 15327770; 15383523; 15485634; 15485837; 15489334; 15670770; 15670977; 15696169; 15707590; 15708970; 15743837; 15861135; 15941918; 15944293; 16009713; 16153868; 16189514; 16214042; 16227629; 16260598; 16263936; 16282325; 16291755; 16304992; 16311516; 16341674; 16378096; 16446357; 16603398; 16611992; 16636664; 16713569; 16876162; 16891304; 16936264; 17015619; 17314283; 17379600; 17384642; 17389591; 17544371; 17599408; 17626074; 17724081; 17851586; 17923499; 18022363; 18024283; 18029348; 18069092; 18230756; 18271526; 18292192; 18312353; 18362156; 18362886; 18671942; 18776134; 18787502; 18818748; 18827186; 18950704; 18981220; 18990758; 19019335; 19150425; 19151112; 19234489; 19243308; 19287455; 19336370; 19380743; 19453261; 19506082; 19527514; 19573080; 19584093; 19586614; 19667091; 19690440; 19773279; 19795416; 19810754; 19815509; 19815541; 19937093; 20005846; 20047764; 20056178; 20064526; 20133937; 20138174; 20184394; 20237496; 20333651; 20348096; 20368287; 20385093; 20447407; 20448643; 20449947; 20562859; 20568250; 20577214; 20585848; 20614026; 20628086; 20676093; 20732415; 20856938; 20949042; 20972266; 20974987; 21041452; 21041727; 21071692; 21078302; 21078624; 21119000; 21139048; 21229359; 21266470; 21282461; 21282507; 21289304; 21325409; 21331077; 21421854; 21620750; 21653699; 21793045; 21810480; 21864338; 21886773; 21890473; 21903422; 21906983; 21921033; 21963094; 21987572; 21988832; 22029577; 22078441; 22167321; 22170762; 22179575; 22184250; 22195745; 22212761; 22271254; 22343716; 22505724; 22525270; 22550173; 22585859; 22685297; 22711886; 22732732; 22792062; 22847298; 22863753; 23000965; 23007157; 23051914; 23088713; 23142077; 23160117; 23188828; 23301098; 23319823; 23357418; 23381138; 23405219; 23414308; 23453969; 23524849; 23543740; 23595117; 23608757; 23624947; 23638224; 23690480; 23743189; 23754945; 23775076; 23885119; 23890813; 23918987; 23972990; 24008839; 24434549; 24457600 TNF receptor-associated factor 2 Ensembl:ENSG00000127191 HGNC:12032 HPRD:03538 MIM:601895 Vega:OTTHUMG00000020952 TRAF2 Bin Zhao, Yue Liu, Oliver He TRSP tRNA(Sec) WEB: http://www.ncbi.nlm.nih.gov/gene TRNAU1 transfer RNA selenocysteine 1 (anticodon UCA) 7234 19q13.2-q13.3 20140408 9606 19 tRNA Official from a nomenclature committee PMID: 1395717; 3156131 transfer RNA selenocysteine 1 (anticodon UCA) HGNC:12348 MIM:165060 TRNAU1 Bin Zhao, Yue Liu, Oliver He RDS WEB: http://www.ncbi.nlm.nih.gov/gene TST thiosulfate sulfurtransferase (rhodanese) 7263 LL22NC01-146D10.3 22q13.1 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0000096 (EC: TAS); GO_0000098 (EC: TAS); GO_0004792 (EC: IEA); GO_0005615 (EC: IDA); GO_0005739 (EC: IDA); GO_0005743 (EC: IEA); GO_0005759 (EC: TAS); GO_0008097 (EC: IDA); GO_0009440 (EC: TAS, PMID: 9070219); GO_0030855 (EC: IDA); GO_0034641 (EC: TAS); GO_0035928 (EC: IMP); GO_0044281 (EC: TAS); GO_0051029 (EC: IDA); GO_0070221 (EC: TAS) PMID: 986188; 1451437; 1691817; 2006499; 2817794; 3178139; 3471602; 3479705; 6402020; 6573305; 6588145; 6928732; 8125298; 8254022; 8340386; 8404072; 9070219; 10591208; 11112515; 11788560; 12477932; 12665801; 12962704; 14702039; 15153070; 15461802; 15489334; 15910006; 16343079; 16500920; 16790311; 17035239; 18029348; 19695240; 20099848; 20663881; 20877624; 21175961; 21685364; 21890473; 21922874; 22939629; 23399736 thiosulfate sulfurtransferase (rhodanese) Ensembl:ENSG00000128311 HGNC:12388 HPRD:01583 MIM:180370 Vega:OTTHUMG00000150533 TST Bin Zhao, Yue Liu, Oliver He rd5 WEB: http://www.ncbi.nlm.nih.gov/gene TUB tubby bipartite transcription factor 7275 11p15.5 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0005576 (EC: IEA); GO_0005634 (EC: IEA); GO_0005737 (EC: TAS, PMID: 11000483); GO_0005829 (EC: IEA); GO_0005886 (EC: IEA); GO_0006909 (EC: IEA); GO_0007602 (EC: IEA); GO_0007605 (EC: IEA); GO_0008020 (EC: IEA); GO_0009725 (EC: IEA); GO_0044259 (EC: IEA); GO_0050766 (EC: IDA, PMID: 19837063); GO_0060041 (EC: IEA) PMID: 1358794; 8612280; 9096357; 10455176; 10591637; 11000483; 11375483; 11801719; 12477932; 15489334; 16443771; 17498679; 17955208; 18029348; 18183286; 19058789; 19077438; 19486527; 19837063; 19913121; 20080650; 20628086; 20935630; 20978472; 22632162; 23000965 tubby bipartite transcription factor Ensembl:ENSG00000166402 HGNC:12406 HPRD:03121 MIM:601197 Vega:OTTHUMG00000165690 TUB Bin Zhao, Yue Liu, Oliver He CTS CTS1 HEL111 HsT2651 PALB TBPA WEB: http://www.ncbi.nlm.nih.gov/gene TTR transthyretin 7276 18q12.1 20140408 9606 18 protein-coding Official from a nomenclature committee GO_0001523 (EC: TAS); GO_0005179 (EC: IEA); GO_0005515 (EC: IPI, PMID: 16716307); GO_0005576 (EC: NAS, PMID: 14718574); GO_0005576 (EC: TAS); GO_0005615 (EC: IEA); GO_0005737 (EC: IEA); GO_0006810 (EC: IEA); GO_0007603 (EC: TAS); GO_0030198 (EC: TAS); GO_0042562 (EC: IEA); GO_0042572 (EC: IEA); GO_0042802 (EC: IPI, PMID: 19861125); GO_0043234 (EC: IEA); GO_0046982 (EC: IEA) PMID: 201845; 574085; 671542; 986177; 1301926; 1351039; 1356051; 1362222; 1436517; 1517749; 1520326; 1520336; 1544214; 1570831; 1602151; 1626570; 1656975; 1666289; 1734866; 1867256; 1877623; 1932142; 1977686; 1979335; 1981182; 1997217; 2015890; 2046936; 2122246; 2161654; 2174830; 2320592; 2360796; 2363717; 2613237; 2693890; 2877582; 2891727; 2990465; 2995367; 3011930; 3022107; 3022108; 3028932; 3135807; 3229002; 3479441; 3675594; 3714052; 3722385; 3760189; 3762958; 3818577; 4044580; 4054629; 4216640; 4328329; 4607556; 4952599; 6087811; 6093805; 6208668; 6300852; 6487335; 6549130; 6583672; 6651852; 7033114; 7417777; 7474944; 7599630; 7754382; 7794243; 7839813; 7850982; 7910950; 7914929; 7923855; 7946531; 8019560; 8038017; 8081397; 8089102; 8095301; 8095302; 8133316; 8218290; 8257997; 8309582; 8352764; 8382610; 8406434; 8428915; 8549676; 8579098; 8692810; 8784093; 8857732; 8960746; 8990019; 9191784; 9307034; 9771673; 9771681; 9789022; 9818054; 9818883; 10052934; 10071047; 10465115; 10529370; 10627135; 10627502; 10671063; 10694917; 10704770; 10742177; 10841549; 10842705; 10845569; 10854215; 10882995; 10982792; 11106758; 11243784; 11418763; 11445644; 11478875; 11577236; 11709003; 11853533; 11913969; 11995997; 12039669; 12082059; 12095258; 12354101; 12403615; 12433265; 12477932; 12481032; 12560553; 12566023; 12593674; 12665801; 12697331; 12771253; 12874414; 12874858; 12876326; 12900507; 13367520; 14506715; 14507924; 14534839; 14578606; 14604984; 14673473; 14690414; 14718574; 14760718; 14981241; 15033978; 15174051; 15210129; 15214015; 15489334; 15536615; 15610856; 15649951; 15736938; 15793844; 15821170; 15930086; 15995833; 16011990; 16053476; 16076613; 16079207; 16114899; 16130282; 16159939; 16169070; 16185074; 16189514; 16194875; 16199891; 16204882; 16219761; 16225852; 16335952; 16386248; 16433699; 16487493; 16552785; 16690497; 16698124; 16716307; 16716350; 16732734; 16751191; 16879610; 16892178; 16893521; 17062384; 17116243; 17143887; 17176092; 17196219; 17203960; 17378745; 17431395; 17466336; 17487420; 17503405; 17558848; 17577688; 17630783; 17671371; 17683281; 17683510; 17698792; 17873539; 17957146; 17968687; 17968690; 17980738; 18022643; 18221012; 18237193; 18242169; 18252270; 18257091; 18275060; 18276611; 18326041; 18406527; 18410945; 18448869; 18460047; 18485534; 18579156; 18624398; 18655780; 18662699; 18682810; 18688962; 18807501; 18825272; 18830126; 18835560; 18925456; 18930252; 19021760; 19118530; 19180884; 19188365; 19250316; 19328595; 19361464; 19389624; 19401362; 19410571; 19428025; 19477408; 19493541; 19501859; 19601795; 19602727; 19626479; 19626480; 19664600; 19703508; 19781421; 19808383; 19861125; 19913121; 19922332; 19922456; 20132088; 20143571; 20211733; 20301373; 20373457; 20388560; 20435197; 20462367; 20547140; 20628086; 20646067; 20659897; 20660862; 20697105; 20735474; 20736409; 20840742; 20949480; 20964562; 21056899; 21077797; 21104416; 21135536; 21174946; 21179560; 21179887; 21191093; 21208750; 21280184; 21335655; 21358362; 21397913; 21406045; 21420946; 21422279; 21434877; 21439703; 21461579; 21521316; 21537325; 21540676; 21600538; 21714897; 21733562; 21739396; 21777382; 21821015; 21841252; 21843040; 21878437; 21880910; 21900206; 21945519; 21945954; 22002789; 22027013; 22045754; 22080762; 22091638; 22102249; 22120741; 22169613; 22228785; 22248451; 22264585; 22301727; 22311483; 22362898; 22412233; 22439750; 22579241; 22592564; 22607976; 22670059; 22698061; 22784244; 22795285; 22826435; 22842046; 22844532; 22889670; 22928869; 22948197; 22949539; 22968245; 22975527; 22984597; 23079095; 23129325; 23133543; 23185504; 23225005; 23225009; 23225017; 23240369; 23244293; 23279339; 23306657; 23319365; 23385359; 23387326; 23414091; 23438977; 23465306; 23523753; 23546595; 23579071; 23580146; 23713495; 23716704; 23734638; 23860318; 23901247; 24030829; 24455802 transthyretin Ensembl:ENSG00000118271 HGNC:12405 HPRD:01447 MIM:176300 Vega:OTTHUMG00000131984 TTR Bin Zhao, Yue Liu, Oliver He TRDX TRX TRX1 WEB: http://www.ncbi.nlm.nih.gov/gene TXN thioredoxin 7295 RP11-427L11.1 9q31 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000122 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11118054); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA); GO_0005739 (EC: IEA); GO_0005829 (EC: TAS); GO_0006351 (EC: IEA); GO_0006662 (EC: IEA); GO_0006928 (EC: TAS, PMID: 10947064); GO_0007165 (EC: TAS, PMID: 10947064); GO_0007267 (EC: TAS, PMID: 10947064); GO_0008283 (EC: TAS, PMID: 3170595); GO_0009314 (EC: IDA, PMID: 11118054); GO_0015035 (EC: IEA); GO_0015037 (EC: IEA); GO_0015949 (EC: TAS); GO_0033158 (EC: IDA, PMID: 11118054); GO_0035872 (EC: TAS); GO_0043388 (EC: IDA, PMID: 11118054); GO_0044281 (EC: TAS); GO_0044822 (EC: IDA); GO_0045087 (EC: TAS); GO_0045454 (EC: IEA); GO_0046826 (EC: IEA); GO_0055086 (EC: TAS); GO_0055114 (EC: IDA, PMID: 11118054); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1874447; 1998498; 2001356; 2176490; 2684271; 2785919; 3170595; 7601465; 7788295; 7821789; 7922028; 8049254; 8736558; 8805557; 9108029; 9369469; 9433926; 9464857; 9564042; 9915858; 10397171; 10419473; 10585464; 10814541; 10843682; 10947064; 10982790; 11012661; 11118054; 11298454; 11323689; 11517226; 11689443; 11751890; 11778846; 11841832; 11972307; 12008049; 12029072; 12089063; 12099690; 12119401; 12189205; 12244106; 12244325; 12477932; 12529245; 12660821; 12804587; 12816947; 12870673; 12878985; 12882768; 14503974; 14644168; 14688353; 14695120; 14703116; 14730345; 15096327; 15128745; 15234975; 15480426; 15489334; 15494431; 15507528; 15694802; 15723974; 15824742; 15894171; 16097034; 16115022; 16207716; 16263712; 16311508; 16424062; 16458196; 16492688; 16507315; 16712525; 16750198; 16766796; 16868544; 16916647; 16966583; 17007870; 17045827; 17113580; 17115890; 17220299; 17316609; 17331951; 17353931; 17360766; 17369362; 17557078; 17574940; 17601350; 17606900; 17634480; 17651689; 17652454; 17724081; 17823364; 17896802; 17917077; 17949784; 17972886; 17982132; 18209488; 18384140; 18420212; 18457020; 18497292; 18544525; 18579387; 18781797; 18835792; 18848838; 18976655; 18977241; 18983687; 19056867; 19120277; 19124506; 19135121; 19208085; 19328186; 19337991; 19385090; 19471022; 19540723; 19558833; 19561639; 19566940; 19592618; 19601712; 19620238; 19671194; 19681600; 19690162; 19723146; 19773351; 19799607; 19913121; 20074557; 20103619; 20172870; 20218863; 20298786; 20347035; 20379614; 20385180; 20423474; 20430109; 20485444; 20536427; 20619274; 20628086; 20661909; 20662007; 20847814; 20877624; 20929309; 20943653; 20955789; 20974843; 21030559; 21139048; 21145461; 21150319; 21158569; 21212402; 21250889; 21319273; 21324905; 21353370; 21526215; 21557999; 21620911; 21636804; 21642987; 21704743; 21705327; 21800051; 21890473; 21906983; 21908620; 21963718; 21988832; 22053931; 22134635; 22248473; 22384152; 22430737; 22447839; 22492997; 22505815; 22516068; 22760822; 22810585; 22863883; 22867430; 22882193; 22933306; 22939629; 22977247; 23000965; 23068965; 23105116; 23133653; 23212077; 23223577; 23238053; 23246001; 23319048; 23335265; 23398456; 23402259; 23455922; 23485938; 23606123; 23671274; 23743503; 23747528; 23862649; 23880345; 24008424; 24062305; 24244333; 24459704 thioredoxin Ensembl:ENSG00000136810 HGNC:12435 HPRD:01761 MIM:187700 Vega:OTTHUMG00000020480 TXN Bin Zhao, Yue Liu, Oliver He DAP12 KARAP PLOSL WEB: http://www.ncbi.nlm.nih.gov/gene TYROBP TYRO protein tyrosine kinase binding protein 7305 19q13.1 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0002281 (EC: IEA); GO_0002283 (EC: IEA); GO_0005057 (EC: TAS, PMID: 9490415); GO_0005102 (EC: IPI, PMID: 15294961); GO_0005515 (EC: IPI, PMID: 10940905); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 9490415); GO_0006968 (EC: TAS, PMID: 9490415); GO_0007165 (EC: TAS, PMID: 9490415); GO_0007229 (EC: IEA); GO_0007411 (EC: TAS); GO_0009986 (EC: IDA, PMID: 15294961); GO_0035556 (EC: TAS, PMID: 9490415); GO_0042802 (EC: IPI); GO_0045087 (EC: TAS); GO_0050776 (EC: TAS); GO_2001204 (EC: IEA) PMID: 8889548; 9463329; 9490415; 9655483; 9828133; 9830044; 10049942; 10201920; 10449773; 10604985; 10799849; 10888890; 10940905; 11169398; 11922939; 12080485; 12207350; 12370476; 12426564; 12426565; 12477932; 12569153; 12591902; 12925681; 14707061; 15294961; 15342556; 15356118; 15489334; 15557162; 16206234; 16339517; 16505336; 16715077; 17012248; 17100880; 17125796; 17202323; 17277102; 17301953; 17530208; 19019460; 19075187; 19120482; 19606219; 20212065; 20301376; 20421649; 20628624; 21263069; 21421043; 21841309; 21967868; 22080356; 23561520; 23715743 TYRO protein tyrosine kinase binding protein Ensembl:ENSG00000011600 HGNC:12449 HPRD:04996 MIM:604142 Vega:OTTHUMG00000181739 TYROBP Bin Zhao, Yue Liu, Oliver He A1S9 A1S9T A1ST AMCX1 GXP1 POC20 SMAX2 UBA1A UBE1 UBE1X WEB: http://www.ncbi.nlm.nih.gov/gene UBA1 ubiquitin-like modifier activating enzyme 1 7317 CTD-2522E6.1 Xp11.23 20140408 9606 X protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 16227972); GO_0005524 (EC: IEA); GO_0008219 (EC: IEA); GO_0008641 (EC: IEA); GO_0016567 (EC: IEA); GO_0016874 (EC: IEA); GO_0044822 (EC: IDA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 1544321; 1606621; 1845793; 1871145; 1986373; 2265617; 2323223; 2390975; 3390177; 7673335; 7724583; 8051045; 8550581; 8573590; 8663123; 9467000; 9644242; 11447495; 11846513; 12477932; 12883554; 12938929; 14702039; 14733918; 15202508; 15247261; 15302935; 15489334; 15576338; 15592455; 15852347; 16169070; 16196087; 16227972; 16263121; 16595681; 16712842; 16713569; 16964243; 17060614; 17580310; 17597759; 17686993; 17956732; 17980597; 18029348; 18179898; 18661401; 18678647; 18781797; 19019082; 19056867; 19135240; 19471022; 19723899; 19850743; 20004025; 20301739; 20360068; 20639865; 20653130; 21081666; 21139048; 21145461; 21252943; 21319273; 21890473; 21900206; 21906983; 21963094; 21987572; 21988832; 22053931; 22069333; 22145905; 22190034; 22279528; 22350887; 22370482; 22427669; 22434192; 22456334; 22505724; 22797925; 22863883; 22939629; 22999844; 23000965; 23003343; 23349634; 23524849; 23801757; 23824909; 23862649 ubiquitin-like modifier activating enzyme 1 Ensembl:ENSG00000130985 HGNC:12469 HPRD:02440 MIM:314370 Vega:OTTHUMG00000021436 UBA1 Bin Zhao, Yue Liu, Oliver He LBP-1B LBP-1a LBP1A LBP1B WEB: http://www.ncbi.nlm.nih.gov/gene UBP1 upstream binding protein 1 (LBP-1a) 7342 3p22.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0001525 (EC: IEA); GO_0003677 (EC: IEA); GO_0003700 (EC: TAS, PMID: 8114710); GO_0003714 (EC: TAS, PMID: 8114710); GO_0005634 (EC: TAS, PMID: 8114710); GO_0006351 (EC: IEA); GO_0006357 (EC: TAS, PMID: 8114710); GO_0019079 (EC: TAS, PMID: 8114710); GO_0045892 (EC: TAS, PMID: 8114710) PMID: 2006421; 7836461; 8114710; 10644752; 12477932; 14702039; 15207707; 15471945; 15489334; 16344560; 18004979; 19322201; 19471022; 19505873; 19662162; 19751393; 20211142; 21956701; 21988832; 22939629 upstream binding protein 1 (LBP-1a) Ensembl:ENSG00000153560 HGNC:12507 HPRD:10291 MIM:609784 Vega:OTTHUMG00000130749 UBP1 Bin Zhao, Yue Liu, Oliver He CD106 INCAM-100 WEB: http://www.ncbi.nlm.nih.gov/gene VCAM1 vascular cell adhesion molecule 1 7412 1p32-p31 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001666 (EC: IEA); GO_0002102 (EC: IDA, PMID: 15220135); GO_0002526 (EC: IEA); GO_0002544 (EC: IEA); GO_0005178 (EC: IDA, PMID: 1377228); GO_0005178 (EC: IMP, PMID: 19738201); GO_0005615 (EC: IDA, PMID: 9290466); GO_0005769 (EC: IDA); GO_0005783 (EC: IDA); GO_0005794 (EC: IDA); GO_0005886 (EC: TAS); GO_0005902 (EC: IDA, PMID: 12082081); GO_0007155 (EC: IDA, PMID: 16809613); GO_0007157 (EC: IDA, PMID: 1715889); GO_0007159 (EC: IDA, PMID: 1381355); GO_0007507 (EC: IEA); GO_0007568 (EC: IEA); GO_0007584 (EC: IEA); GO_0008131 (EC: IDA); GO_0009308 (EC: IDA); GO_0009897 (EC: IDA, PMID: 1377228); GO_0009986 (EC: IDA, PMID: 1715889); GO_0010043 (EC: IEA); GO_0010212 (EC: IEA); GO_0016021 (EC: IEA); GO_0016032 (EC: IEA); GO_0019221 (EC: TAS); GO_0022614 (EC: IEP, PMID: 12082081); GO_0030175 (EC: IDA, PMID: 12082081); GO_0030183 (EC: IC, PMID: 1715889); GO_0030198 (EC: TAS); GO_0032496 (EC: IEA); GO_0035094 (EC: IEA); GO_0035924 (EC: IEA); GO_0042102 (EC: IDA, PMID: 1381355); GO_0042383 (EC: IEA); GO_0045177 (EC: IDA, PMID: 12082081); GO_0045471 (EC: IEA); GO_0050776 (EC: TAS); GO_0050839 (EC: IDA, PMID: 1377228); GO_0050839 (EC: IPI, PMID: 12082081); GO_0050901 (EC: IEP, PMID: 2688898); GO_0055114 (EC: IDA); GO_0060326 (EC: IEA); GO_0060333 (EC: TAS); GO_0060710 (EC: IEA); GO_0071065 (EC: IDA, PMID: 15220135); GO_0071333 (EC: IEA); GO_0071356 (EC: IEA) PMID: 1281211; 1377228; 1379595; 1381355; 1699207; 1707234; 1707873; 1713772; 1715583; 1715889; 2688898; 7521694; 7531291; 7534402; 7539925; 7545397; 7691867; 7884872; 8125298; 8607877; 8825878; 8977311; 9117345; 9184636; 9269771; 9290466; 9443894; 9603478; 9792375; 9973426; 10209034; 10377075; 10438935; 10477700; 10556825; 10602408; 10623819; 10944555; 11123288; 11517385; 11520773; 11776680; 11817523; 11847011; 11882338; 11904449; 11922919; 11929779; 11935152; 11961404; 11963839; 11983205; 12006387; 12082081; 12086338; 12097820; 12105209; 12115600; 12172318; 12172576; 12193695; 12351381; 12387879; 12393616; 12433638; 12477932; 12493764; 12587980; 12601490; 12643440; 12650924; 12673844; 12682249; 12700137; 12704784; 12714597; 12759453; 12788528; 12871600; 12940514; 12958610; 12969778; 14534081; 14550782; 14592496; 14615367; 14684616; 14691297; 14741380; 14748068; 14762656; 14984317; 15009098; 15059493; 15078922; 15080580; 15116247; 15175347; 15194470; 15220135; 15225366; 15265790; 15299708; 15304054; 15308572; 15340161; 15489334; 15489374; 15489375; 15525877; 15548573; 15661077; 15661918; 15666579; 15710215; 15784173; 15805138; 15806475; 15845907; 15979542; 16002075; 16015337; 16127297; 16184405; 16230423; 16242117; 16317091; 16327982; 16335952; 16344560; 16498082; 16585601; 16644735; 16722038; 16790997; 16809613; 16874958; 16902065; 16914554; 16977262; 16987074; 17008592; 17022986; 17090406; 17115186; 17116732; 17126824; 17142773; 17167725; 17192354; 17255534; 17258924; 17292586; 17303384; 17334226; 17352405; 17430469; 17431880; 17437524; 17497038; 17517105; 17521609; 17530710; 17531998; 17560459; 17564956; 17586618; 17597073; 17599409; 17616653; 17657162; 17678915; 17702963; 17703412; 17706337; 17706953; 17714716; 17891599; 17906965; 17922685; 17943642; 17962718; 17963163; 17964973; 17983593; 18078450; 18160848; 18197885; 18212564; 18227515; 18284603; 18326231; 18383329; 18406566; 18420209; 18421029; 18449421; 18462748; 18473733; 18482273; 18490752; 18504269; 18554449; 18564921; 18574676; 18582564; 18597403; 18600396; 18613029; 18618671; 18628303; 18633131; 18636124; 18656701; 18666029; 18676680; 18676870; 18692491; 18707907; 18761738; 18778820; 18787016; 18787184; 18791689; 18813849; 18828734; 18834676; 18846968; 18930765; 18974842; 19002703; 19021457; 19022587; 19028820; 19057841; 19074885; 19131662; 19134480; 19136619; 19170196; 19208843; 19210349; 19225544; 19229069; 19236760; 19237221; 19242838; 19247692; 19249917; 19258923; 19281832; 19342863; 19353432; 19379571; 19391499; 19399399; 19407977; 19407978; 19417018; 19422386; 19423540; 19452728; 19479237; 19520742; 19526283; 19540498; 19542447; 19554506; 19559392; 19573080; 19597294; 19604093; 19625176; 19692168; 19717975; 19729601; 19738201; 19771922; 19773279; 19812370; 19887846; 19913121; 19948975; 20039412; 20056178; 20112284; 20164172; 20184510; 20197690; 20217071; 20219985; 20233927; 20237496; 20360250; 20405289; 20406964; 20416077; 20430730; 20438785; 20447702; 20482449; 20485444; 20503287; 20508517; 20536507; 20568250; 20573493; 20602615; 20603037; 20628086; 20685094; 20714774; 20851866; 20864106; 20880684; 20929696; 20935502; 20966071; 21030716; 21037509; 21073443; 21099224; 21144825; 21162967; 21172429; 21177856; 21183871; 21184654; 21214384; 21236267; 21381877; 21520070; 21540635; 21562063; 21594636; 21632263; 21641584; 21804483; 21808112; 21833088; 21843619; 21895545; 21900123; 22001052; 22014578; 22031842; 22093255; 22137570; 22137794; 22183741; 22195873; 22209080; 22209338; 22269951; 22298164; 22324942; 22366735; 22374129; 22384064; 22448134; 22463742; 22497223; 22505707; 22539325; 22552687; 22591361; 22593994; 22623428; 22664325; 22694757; 22717098; 22719189; 22734001; 22740338; 22742445; 22874466; 22879387; 22905988; 22976263; 23042271; 23057424; 23058024; 23117931; 23185512; 23232649; 23242661; 23285079; 23313051; 23336423; 23344094; 23349048; 23396735; 23463506; 23665024; 23677452; 23679262; 23704882; 23792525; 23934855; 24045955; 24157824; 24282904 vascular cell adhesion molecule 1 Ensembl:ENSG00000162692 HGNC:12663 HPRD:01888 MIM:192225 Vega:OTTHUMG00000010982 VCAM1 Bin Zhao, Yue Liu, Oliver He MVCD1 VEGF VPF WEB: http://www.ncbi.nlm.nih.gov/gene VEGFA vascular endothelial growth factor A 7422 RP1-261G23.1 6p12 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000122 (EC: IDA, PMID: 18093989); GO_0001525 (EC: IDA, PMID: 11427521); GO_0001541 (EC: ISS); GO_0001569 (EC: ISS); GO_0001570 (EC: TAS, PMID: 15015550); GO_0001666 (EC: IDA, PMID: 16490744); GO_0001701 (EC: ISS); GO_0001822 (EC: ISS); GO_0001934 (EC: IDA, PMID: 18386220); GO_0001938 (EC: IDA, PMID: 10022831); GO_0001938 (EC: ISS); GO_0001968 (EC: IDA, PMID: 14570917); GO_0002042 (EC: IDA, PMID: 18059339); GO_0002052 (EC: ISS); GO_0002053 (EC: ISS); GO_0002092 (EC: IDA); GO_0002575 (EC: IDA, PMID: 17082651); GO_0002576 (EC: TAS); GO_0002687 (EC: TAS, PMID: 1312256); GO_0003007 (EC: ISS); GO_0003151 (EC: ISS); GO_0003169 (EC: ISS); GO_0005125 (EC: IDA, PMID: 18440775); GO_0005125 (EC: ISS); GO_0005161 (EC: IPI, PMID: 17470632); GO_0005172 (EC: IPI, PMID: 10471394); GO_0005515 (EC: IPI, PMID: 10543948); GO_0005576 (EC: TAS); GO_0005578 (EC: NAS, PMID: 14570917); GO_0005615 (EC: IDA, PMID: 16490744); GO_0005615 (EC: ISS); GO_0005737 (EC: IDA, PMID: 17082651); GO_0006357 (EC: IMP, PMID: 18093989); GO_0007399 (EC: TAS, PMID: 15351965); GO_0007498 (EC: ISS); GO_0007595 (EC: ISS); GO_0007596 (EC: TAS); GO_0008083 (EC: IDA); GO_0008083 (EC: ISS); GO_0008201 (EC: IDA, PMID: 15001987); GO_0008201 (EC: IMP, PMID: 14570917); GO_0008284 (EC: IDA, PMID: 7929439); GO_0008360 (EC: IDA, PMID: 10527820); GO_0009986 (EC: IDA, PMID: 17470632); GO_0010595 (EC: IDA, PMID: 10022831); GO_0010628 (EC: IDA, PMID: 18386220); GO_0016020 (EC: IEA); GO_0030141 (EC: IDA, PMID: 17082651); GO_0030168 (EC: TAS); GO_0030224 (EC: IDA); GO_0030225 (EC: IDA); GO_0030324 (EC: ISS); GO_0030335 (EC: IDA, PMID: 17470632); GO_0030855 (EC: ISS); GO_0030949 (EC: IDA, PMID: 1312256); GO_0031077 (EC: ISS); GO_0031093 (EC: TAS); GO_0031334 (EC: IDA, PMID: 16489009); GO_0031954 (EC: IDA, PMID: 17470632); GO_0032147 (EC: IDA, PMID: 18059339); GO_0032793 (EC: IDA); GO_0033138 (EC: IDA, PMID: 18440775); GO_0035148 (EC: IDA, PMID: 19033661); GO_0035767 (EC: IDA, PMID: 18440775); GO_0035924 (EC: IDA, PMID: 18440775); GO_0036303 (EC: ISS); GO_0038033 (EC: IDA, PMID: 18440775); GO_0038091 (EC: IDA, PMID: 17470632); GO_0038190 (EC: ISS); GO_0040007 (EC: ISS); GO_0042056 (EC: IDA, PMID: 17082651); GO_0042462 (EC: ISS); GO_0042802 (EC: IPI, PMID: 12207021); GO_0042803 (EC: ISS); GO_0043066 (EC: IMP, PMID: 10066377); GO_0043117 (EC: IDA, PMID: 16109918); GO_0043129 (EC: ISS); GO_0043154 (EC: IDA, PMID: 18386220); GO_0043183 (EC: IPI, PMID: 1312256); GO_0043184 (EC: IPI, PMID: 10022831); GO_0043406 (EC: IDA, PMID: 18440775); GO_0043536 (EC: IDA, PMID: 18440775); GO_0045766 (EC: IDA, PMID: 18440775); GO_0045766 (EC: IMP, PMID: 18275976); GO_0045785 (EC: IDA, PMID: 19674970); GO_0045944 (EC: IDA, PMID: 18059339); GO_0045944 (EC: IMP, PMID: 18093989); GO_0046982 (EC: IDA, PMID: 8702615); GO_0048010 (EC: IDA); GO_0048010 (EC: TAS); GO_0048018 (EC: IPI, PMID: 17470632); GO_0048469 (EC: ISS); GO_0048593 (EC: ISS); GO_0048739 (EC: ISS); GO_0048754 (EC: ISS); GO_0048842 (EC: ISS); GO_0048844 (EC: ISS); GO_0050679 (EC: ISS); GO_0050731 (EC: IDA, PMID: 10022831); GO_0050840 (EC: IC, PMID: 14570917); GO_0050918 (EC: IDA, PMID: 19275959); GO_0050927 (EC: IDA, PMID: 12744932); GO_0050930 (EC: IDA, PMID: 19275959); GO_0050930 (EC: NAS, PMID: 12744932); GO_0051272 (EC: IDA, PMID: 10527820); GO_0051781 (EC: IEA); GO_0051894 (EC: IDA, PMID: 16489009); GO_0060319 (EC: ISS); GO_0060749 (EC: ISS); GO_0060754 (EC: IDA, PMID: 19275959); GO_0060948 (EC: ISS); GO_0060982 (EC: ISS); GO_0061418 (EC: TAS); GO_0061419 (EC: IMP, PMID: 19652095); GO_0071456 (EC: IDA, PMID: 10575000); GO_0071456 (EC: TAS); GO_0071542 (EC: ISS); GO_0071679 (EC: ISS); GO_0090037 (EC: IDA, PMID: 18059339); GO_0090050 (EC: IDA); GO_0090190 (EC: ISS); GO_0090259 (EC: ISS); GO_1900086 (EC: IDA); GO_1900745 (EC: IDA, PMID: 18386220); GO_1901727 (EC: IDA); GO_1902336 (EC: ISS); GO_1902533 (EC: IDA) PMID: 1312256; 1417831; 1550962; 1567395; 1711045; 1791831; 2479986; 2479987; 2584205; 7518352; 7525053; 7678805; 7681362; 7759509; 7829517; 7929439; 8621427; 8631822; 8641698; 8702615; 8786112; 8889548; 9012504; 9012841; 9054410; 9202027; 9207067; 9323936; 9336848; 9351807; 9393862; 9450968; 9529250; 9634701; 9674707; 9684805; 9716565; 9792673; 9878851; 9922142; 10022831; 10066377; 10067980; 10196157; 10409677; 10464055; 10471394; 10527820; 10543948; 10575000; 10585578; 10626738; 10748121; 10873597; 11016853; 11032698; 11069235; 11115828; 11122379; 11133233; 11146397; 11196464; 11352659; 11427521; 11461089; 11563986; 11642726; 11686329; 11705851; 11705867; 11731620; 11741977; 11742492; 11744618; 11748975; 11751905; 11783119; 11784713; 11784722; 11796824; 11806247; 11809675; 11809713; 11815711; 11819817; 11824377; 11831981; 11832343; 11834731; 11836562; 11839635; 11847008; 11866530; 11866538; 11867956; 11875709; 11877311; 11877669; 11882460; 11891801; 11908876; 11912213; 11912219; 11920479; 11921018; 11930687; 11930688; 11940485; 11956584; 11956638; 11957147; 11959648; 11960372; 11961297; 11961303; 11964077; 11964307; 11972026; 11978184; 11978667; 11980898; 11986311; 11986954; 11999550; 12012273; 12014632; 12016145; 12023772; 12038454; 12039075; 12042276; 12058259; 12062186; 12067896; 12067976; 12085210; 12086892; 12089333; 12102661; 12105188; 12114504; 12117969; 12119553; 12124351; 12127077; 12133473; 12133520; 12133521; 12141529; 12149254; 12151344; 12151391; 12163680; 12168088; 12168808; 12168898; 12174362; 12174901; 12187074; 12197476; 12207021; 12208766; 12209585; 12209725; 12213806; 12213874; 12213878; 12215337; 12232762; 12235106; 12239588; 12358602; 12391145; 12391545; 12393542; 12400015; 12406876; 12407018; 12413884; 12425822; 12427739; 12427750; 12428103; 12429966; 12430738; 12439912; 12445161; 12446667; 12451991; 12452000; 12453880; 12453985; 12456629; 12474525; 12477932; 12481883; 12482858; 12482957; 12493399; 12496364; 12499259; 12505748; 12509426; 12509854; 12517803; 12545153; 12546587; 12548213; 12551914; 12553038; 12558813; 12563064; 12568850; 12574959; 12579315; 12581744; 12590639; 12591230; 12591731; 12593846; 12594002; 12594815; 12597245; 12604407; 12607595; 12607599; 12615701; 12629515; 12631341; 12637571; 12646239; 12651930; 12654193; 12654197; 12660426; 12666706; 12667326; 12668280; 12668286; 12670505; 12684660; 12684689; 12687277; 12696078; 12700666; 12708473; 12710853; 12711260; 12714610; 12716475; 12716911; 12719950; 12727858; 12740269; 12742981; 12744932; 12756808; 12763746; 12767510; 12788875; 12796773; 12800229; 12810642; 12810677; 12810700; 12827055; 12839933; 12844492; 12845559; 12845630; 12845639; 12847526; 12850503; 12855698; 12860293; 12865814; 12871382; 12871881; 12883661; 12883688; 12883692; 12888890; 12890905; 12893367; 12901801; 12918061; 12926153; 12937141; 12949011; 12957716; 14500349; 14507446; 14507641; 14512169; 14512791; 14513045; 14513053; 14514674; 14530810; 14532971; 14555767; 14559444; 14570917; 14572781; 14574404; 14585871; 14593238; 14600159; 14602779; 14604996; 14607580; 14607712; 14609725; 14610338; 14633511; 14633819; 14634801; 14644752; 14644771; 14647449; 14648803; 14654077; 14655184; 14656735; 14656883; 14659975; 14660505; 14667896; 14669345; 14670179; 14672622; 14674128; 14675094; 14676217; 14676843; 14681237; 14691147; 14694016; 14699103; 14702039; 14704231; 14708636; 14712484; 14714296; 14715242; 14719060; 14719080; 14726393; 14728692; 14729621; 14729679; 14735189; 14741347; 14747470; 14747750; 14749705; 14753452; 14759416; 14762365; 14764537; 14764596; 14767538; 14767569; 14871830; 14959852; 14962110; 14977835; 14981918; 14983012; 14988276; 14997002; 15001987; 15009103; 15014023; 15015550; 15015562; 15040022; 15047611; 15050452; 15051508; 15052220; 15059159; 15063730; 15067085; 15073116; 15081313; 15086939; 15090854; 15093699; 15112337; 15117722; 15118294; 15120936; 15122338; 15126502; 15126581; 15127326; 15135240; 15135259; 15140509; 15140761; 15146197; 15149853; 15153787; 15160911; 15161630; 15161709; 15161830; 15168728; 15173661; 15175342; 15180964; 15184633; 15188178; 15191350; 15191555; 15201500; 15213335; 15217829; 15217947; 15217952; 15239258; 15244100; 15246970; 15247002; 15254682; 15254962; 15256791; 15263820; 15265021; 15273288; 15274325; 15283056; 15284224; 15292252; 15298982; 15302276; 15309707; 15329326; 15331549; 15334691; 15338501; 15339792; 15340161; 15342781; 15345585; 15347673; 15347840; 15351862; 15351965; 15358155; 15374700; 15374715; 15374730; 15375582; 15388333; 15453096; 15453394; 15453815; 15457582; 15458440; 15458509; 15470196; 15474072; 15474081; 15474452; 15475194; 15477409; 15477421; 15489334; 15492846; 15492987; 15494412; 15500293; 15503824; 15503825; 15515423; 15515495; 15516835; 15522212; 15532726; 15540202; 15541813; 15542434; 15548611; 15556999; 15562207; 15568021; 15569051; 15569052; 15580293; 15583754; 15583822; 15583829; 15588162; 15607642; 15609122; 15609132; 15610240; 15610528; 15613104; 15614129; 15621731; 15629128; 15631865; 15633213; 15635051; 15638384; 15640157; 15646833; 15649874; 15653207; 15661835; 15661856; 15664512; 15665295; 15667531; 15667866; 15668894; 15669079; 15671530; 15674338; 15674425; 15682485; 15701844; 15704107; 15705187; 15705790; 15708566; 15714497; 15726914; 15731179; 15732116; 15733833; 15735682; 15741444; 15742396; 15745839; 15746194; 15754021; 15754412; 15756443; 15763997; 15767331; 15770733; 15776280; 15777969; 15788677; 15788755; 15809749; 15820807; 15826815; 15838334; 15838884; 15845615; 15847702; 15864753; 15871723; 15878754; 15880052; 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22270936; 22274866; 22275161; 22287745; 22289522; 22292637; 22296200; 22307775; 22307787; 22308085; 22311631; 22314268; 22315135; 22318385; 22318724; 22319020; 22320189; 22321253; 22328776; 22337942; 22344539; 22350794; 22355348; 22363824; 22368191; 22370607; 22380724; 22382924; 22385323; 22385934; 22386962; 22392094; 22392487; 22392726; 22395988; 22397762; 22399811; 22402207; 22402885; 22402934; 22407444; 22409847; 22417860; 22429695; 22431315; 22433249; 22437209; 22452999; 22455137; 22460086; 22461367; 22471664; 22472004; 22475441; 22475893; 22479202; 22489699; 22493900; 22494072; 22497886; 22506349; 22510875; 22511716; 22513751; 22517242; 22521084; 22527851; 22528855; 22534113; 22541785; 22542989; 22547925; 22548401; 22552325; 22553402; 22558473; 22558480; 22564870; 22568177; 22569438; 22573202; 22577248; 22580375; 22581182; 22581719; 22587628; 22590832; 22594508; 22609636; 22612323; 22612467; 22613408; 22622799; 22635523; 22640261; 22643235; 22644871; 22645074; 22652447; 22652457; 22659165; 22659470; 22659681; 22670172; 22674805; 22675957; 22677927; 22685266; 22689615; 22689881; 22690749; 22692760; 22694909; 22696064; 22697069; 22699049; 22699054; 22699060; 22699782; 22699808; 22705563; 22711306; 22729570; 22729710; 22730813; 22733742; 22735262; 22740248; 22762535; 22763125; 22768249; 22771446; 22773844; 22776467; 22781068; 22786655; 22789536; 22790437; 22791116; 22795057; 22796052; 22800355; 22813402; 22818823; 22819906; 22833169; 22836100; 22840423; 22848663; 22849380; 22850906; 22853925; 22854047; 22855059; 22855159; 22864531; 22864925; 22865486; 22869459; 22872519; 22872931; 22875307; 22876972; 22877565; 22882209; 22899753; 22901144; 22901561; 22906062; 22915033; 22915086; 22925497; 22926658; 22927437; 22930318; 22931643; 22935455; 22942646; 22944463; 22948895; 22951014; 22956610; 22957090; 22961433; 22962287; 22963269; 22965144; 22992725; 22993129; 22993299; 22994042; 22994764; 23005896; 23015149; 23020605; 23025904; 23029477; 23038639; 23039092; 23040494; 23053181; 23058011; 23059773; 23060442; 23061744; 23062326; 23062640; 23064377; 23065156; 23065202; 23065534; 23068100; 23073296; 23077562; 23086295; 23086340; 23086933; 23093658; 23094709; 23098361; 23098453; 23102786; 23104639; 23104894; 23108136; 23114032; 23117246; 23118492; 23128854; 23129289; 23137522; 23145112; 23151382; 23155231; 23155236; 23155356; 23160675; 23161411; 23166713; 23167810; 23168996; 23169005; 23169435; 23172303; 23176363; 23177780; 23181555; 23182805; 23192572; 23201159; 23204297; 23206462; 23211130; 23212515; 23213275; 23217559; 23220088; 23221067; 23222716; 23224211; 23225320; 23227881; 23232696; 23236677; 23236888; 23239744; 23243026; 23250775; 23254909; 23254958; 23257745; 23263486; 23264084; 23264219; 23265127; 23269488; 23269798; 23272057; 23272609; 23279742; 23280079; 23285958; 23288726; 23290762; 23293030; 23293323; 23295255; 23302311; 23313225; 23315815; 23317892; 23321169; 23321170; 23326384; 23326500; 23328414; 23329570; 23332132; 23332617; 23334331; 23335070; 23335846; 23339636; 23340303; 23346798; 23350126; 23350655; 23352645; 23353010; 23359195; 23364276; 23367565; 23369005; 23370341; 23374220; 23374253; 23383089; 23384557; 23390884; 23398358; 23401860; 23403511; 23404377; 23405237; 23408906; 23413901; 23421785; 23421942; 23428182; 23429328; 23429999; 23430447; 23435217; 23444216; 23449351; 23454149; 23454747; 23455636; 23459872; 23462604; 23465821; 23467576; 23470436; 23475388; 23481572; 23485997; 23499421; 23511629; 23522390; 23542734; 23545315; 23548900; 23552871; 23553563; 23554900; 23555666; 23559636; 23569009; 23572336; 23586368; 23588859; 23589053; 23592000; 23599627; 23602531; 23605255; 23608225; 23613250; 23613251; 23613412; 23618468; 23620752; 23625573; 23639731; 23644986; 23648010; 23649946; 23650550; 23651239; 23656623; 23661335; 23667446; 23673188; 23679262; 23679318; 23687977; 23688054; 23690937; 23695013; 23698113; 23699597; 23711375; 23714383; 23719599; 23722461; 23725153; 23725155; 23728502; 23737289; 23737650; 23745581; 23748230; 23749886; 23754270; 23754948; 23756256; 23759331; 23761723; 23765166; 23767832; 23780896; 23790363; 23794239; 23831623; 23831629; 23838139; 23838428; 23840094; 23848209; 23851330; 23860526; 23861821; 23867510; 23870474; 23877020; 23884416; 23884772; 23884891; 23886195; 23886210; 23904001; 23906304; 23907576; 23913375; 23922493; 23926105; 23929745; 23933698; 23950980; 23953100; 23953866; 23976881; 23982876; 23992143; 23998120; 24005038; 24016866; 24021340; 24021586; 24024441; 24043765; 24048796; 24052076; 24067461; 24120473; 24123039; 24222145; 24225154; 24254563; 24263190; 24274376; 24284961; 24321896; 24341227; 24400721; 24403492; 24510998; 24511001 vascular endothelial growth factor A Ensembl:ENSG00000112715 HGNC:12680 HPRD:01889 MIM:192240 Vega:OTTHUMG00000014745 VEGFA Bin Zhao, Yue Liu, Oliver He HRCA1 RCA1 VHL1 pVHL WEB: http://www.ncbi.nlm.nih.gov/gene VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 7428 3p25.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000122 (EC: TAS, PMID: 7660122); GO_0000902 (EC: NAS, PMID: 12169691); GO_0004842 (EC: TAS); GO_0005515 (EC: IPI, PMID: 11641274); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005739 (EC: NAS, PMID: 12169691); GO_0005783 (EC: NAS, PMID: 12169691); GO_0005829 (EC: TAS); GO_0006355 (EC: IMP, PMID: 15824735); GO_0006508 (EC: TAS, PMID: 10353251); GO_0006950 (EC: NAS, PMID: 12169691); GO_0008134 (EC: IPI, PMID: 11641274); GO_0008285 (EC: TAS, PMID: 7660130); GO_0016020 (EC: IEA); GO_0016567 (EC: IMP, PMID: 12169691); GO_0019899 (EC: IPI, PMID: 11641274); GO_0043066 (EC: NAS, PMID: 12169691); GO_0045111 (EC: IDA); GO_0045597 (EC: NAS, PMID: 12169691); GO_0045893 (EC: IMP, PMID: 17973242); GO_0050821 (EC: NAS, PMID: 12169691); GO_0061418 (EC: TAS); GO_0061428 (EC: IDA, PMID: 11641274); GO_0071456 (EC: TAS) PMID: 1673491; 7563486; 7566098; 7604013; 7660122; 7660130; 7690964; 7728151; 7759077; 7829101; 7987306; 7987327; 8069849; 8183553; 8270255; 8493574; 8522307; 8550742; 8592333; 8634692; 8674032; 8700833; 8730290; 8733131; 8765323; 8825918; 8863170; 8931697; 8956040; 9122164; 9156047; 9271438; 9341197; 9399847; 9447969; 9651579; 9663592; 9671762; 9751722; 9829911; 9829912; 9880225; 10205047; 10318914; 10353251; 10364675; 10408776; 10421634; 10449727; 10491320; 10523847; 10533030; 10535940; 10587522; 10627136; 10635329; 10823831; 10850420; 10878807; 10944113; 10973499; 11024059; 11226425; 11292861; 11292862; 11331613; 11358837; 11384984; 11483638; 11504942; 11517223; 11545595; 11566883; 11574546; 11641274; 11709017; 11739384; 11749004; 11779168; 11840338; 11865071; 11865075; 11908068; 11921283; 11986208; 11987242; 11990703; 12000816; 12004076; 12016154; 12032852; 12036906; 12048197; 12050673; 12056827; 12086860; 12086861; 12097293; 12114475; 12114495; 12169691; 12205091; 12209156; 12351678; 12374282; 12378530; 12393546; 12414898; 12415268; 12460920; 12464182; 12468553; 12477932; 12482756; 12490973; 12510195; 12511881; 12538644; 12586829; 12604794; 12606543; 12609565; 12640117; 12644949; 12673678; 12682018; 12682336; 12684640; 12692265; 12697815; 12743597; 12767066; 12781449; 12808024; 12810083; 12821933; 12839965; 12844285; 12912922; 12925778; 12937142; 13679920; 13985160; 14506252; 14517280; 14531799; 14556007; 14600153; 14604959; 14636579; 14667507; 14691445; 14691554; 14722919; 14726398; 14729622; 14767570; 14963040; 14973063; 14985465; 15060148; 15082527; 15084514; 15122713; 15162797; 15231748; 15300849; 15448019; 15467305; 15530850; 15572213; 15601820; 15604095; 15607616; 15608669; 15611064; 15696489; 15721254; 15750626; 15777842; 15805242; 15809750; 15824109; 15824735; 15849821; 15893810; 15921386; 15932632; 15935760; 15962286; 15966899; 15985433; 15998523; 16107702; 16140212; 16142346; 16144691; 16170373; 16208141; 16210343; 16234850; 16261165; 16278378; 16314641; 16325183; 16407835; 16503656; 16506218; 16511565; 16611863; 16669786; 16678111; 16707008; 16768548; 16769276; 16849532; 16856496; 16884327; 16892044; 16951198; 16983094; 17006605; 17047048; 17060462; 17069461; 17101696; 17102080; 17132228; 17200123; 17244529; 17245122; 17255293; 17264095; 17296901; 17339318; 17344222; 17350623; 17353931; 17407064; 17438007; 17439941; 17450132; 17486080; 17526729; 17555795; 17558023; 17568584; 17639058; 17661816; 17680521; 17688370; 17696210; 17698809; 17786294; 17825299; 17828303; 17846357; 17898043; 17906660; 17912253; 17919893; 17922844; 17936701; 17954272; 17967880; 17973242; 17973296; 17981124; 17986458; 17997830; 17998064; 18072267; 18073334; 18079682; 18085246; 18094722; 18162774; 18173839; 18187417; 18212329; 18222538; 18223282; 18245539; 18264140; 18285459; 18305400; 18323857; 18359287; 18389622; 18408496; 18416845; 18423895; 18424433; 18426857; 18446368; 18474617; 18517280; 18551016; 18559510; 18607865; 18635227; 18676741; 18685280; 18694926; 18751708; 18751980; 18775313; 18780286; 18806787; 18836774; 18950731; 18985005; 18998488; 19018165; 19029228; 19030229; 19056930; 19061835; 19062180; 19064569; 19073886; 19123984; 19133167; 19145771; 19147576; 19158274; 19159641; 19162062; 19208735; 19215943; 19216840; 19223516; 19228690; 19238077; 19252526; 19258401; 19280651; 19288063; 19305426; 19322201; 19336503; 19336759; 19340311; 19343621; 19351817; 19399650; 19401348; 19408298; 19411751; 19419968; 19458911; 19464057; 19464396; 19525194; 19574279; 19584355; 19602254; 19620968; 19629420; 19649731; 19690016; 19695223; 19706539; 19759417; 19764026; 19801654; 19806577; 19808854; 19814753; 19825962; 19906784; 19913121; 19915015; 19915370; 19933033; 19940151; 19940550; 20049704; 20068166; 20137853; 20145706; 20151405; 20185829; 20205103; 20208144; 20300531; 20301636; 20301715; 20375333; 20382342; 20382408; 20420027; 20431476; 20447124; 20453000; 20560986; 20567917; 20599784; 20628086; 20637892; 20639871; 20651059; 20680678; 20724477; 20802534; 20844582; 20855504; 20863722; 20871634; 20952286; 20964835; 20973793; 20978146; 20978319; 20980436; 21042786; 21139048; 21145461; 21151099; 21204227; 21233420; 21258414; 21299348; 21332579; 21335603; 21358672; 21362373; 21386872; 21386990; 21415706; 21436690; 21463266; 21493813; 21528828; 21547579; 21556796; 21602888; 21602890; 21606165; 21625219; 21632985; 21642472; 21658608; 21685785; 21685897; 21715564; 21725364; 21763962; 21778301; 21791076; 21798997; 21832049; 21876117; 21888897; 21890473; 21942715; 21949687; 21972040; 21993671; 22006925; 22020339; 22022277; 22071692; 22084938; 22086907; 22105711; 22125026; 22150821; 22156657; 22234250; 22270996; 22284679; 22286099; 22286234; 22351759; 22357542; 22389506; 22393103; 22438210; 22462637; 22516261; 22532874; 22585604; 22642103; 22649212; 22673518; 22673568; 22714833; 22718905; 22799452; 22806541; 22825683; 22906772; 22931246; 22932900; 22946750; 22948661; 23011899; 23063455; 23074928; 23079206; 23151618; 23159849; 23203444; 23217559; 23224817; 23255108; 23298237; 23315288; 23318261; 23338840; 23387829; 23393199; 23395608; 23401859; 23403324; 23434161; 23455924; 23473032; 23481210; 23558940; 23580587; 23601303; 23611775; 23612971; 23626751; 23730213; 23785518; 23788249; 23840444; 23872148; 23902947; 23928302; 23961993; 23964080; 23976881; 23990666; 24002598; 24015760; 24029645; 24067370; 24112038; 24145437; 24166983; 24250222; 24316222; 24335534; 24344197 von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase HGNC:12687 HPRD:01905 MIM:608537 VHL Bin Zhao, Yue Liu, Oliver He CARMQ1 CHRMQ1 VLDLRCH WEB: http://www.ncbi.nlm.nih.gov/gene VLDLR very low density lipoprotein receptor 7436 RP11-320E16.1 9p24 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000122 (EC: ISS); GO_0001948 (EC: IPI, PMID: 10571240); GO_0005041 (EC: TAS, PMID: 10380922); GO_0005509 (EC: IEA); GO_0005515 (EC: IPI, PMID: 8083232); GO_0005886 (EC: TAS, PMID: 10380922); GO_0005905 (EC: IEA); GO_0006869 (EC: IEA); GO_0006898 (EC: IDA, PMID: 10571240); GO_0007165 (EC: TAS, PMID: 10380922); GO_0007399 (EC: TAS, PMID: 10380922); GO_0007613 (EC: TAS, PMID: 7550352); GO_0008203 (EC: IEA); GO_0016020 (EC: IDA, PMID: 15082773); GO_0016021 (EC: IEA); GO_0021517 (EC: IEA); GO_0030229 (EC: IDA, PMID: 8083232); GO_0034185 (EC: IDA, PMID: 10571240); GO_0034185 (EC: ISS); GO_0034189 (EC: IDA, PMID: 10571240); GO_0034361 (EC: IEA); GO_0034436 (EC: IDA, PMID: 10571240); GO_0034437 (EC: IDA, PMID: 10571240); GO_0034447 (EC: IDA, PMID: 8083232); GO_0038025 (EC: ISS); GO_0038026 (EC: ISS); GO_0043235 (EC: IDA); GO_0045860 (EC: IEA); GO_0048306 (EC: IPI, PMID: 10571240); GO_1900006 (EC: ISS) PMID: 7550352; 7592875; 7797576; 7828550; 8020981; 8069294; 8083232; 8128315; 8294473; 9132912; 9555943; 9630508; 10380922; 10391209; 10571240; 10571241; 10629142; 10827173; 11266465; 11342683; 11931574; 12167620; 12169628; 12363388; 12477932; 12670700; 12824284; 12857919; 12899622; 14702039; 15064754; 15082773; 15164053; 15863833; 15950758; 15950998; 15953542; 16080122; 16384981; 17330141; 17472347; 17854420; 17890782; 17936586; 18032585; 18039658; 18043714; 18056683; 18277139; 18326629; 18364738; 18685438; 19015224; 19224153; 19393635; 19913121; 20301729; 20427281; 20624392; 20628086; 21047397; 21063833; 21601501; 21642441; 21734303; 21757650; 21890473; 21963094; 21987572; 22005931; 22109552; 22170052; 22189190; 22355348; 22419519; 22532556; 22780124; 22876580; 22973972; 23000965; 23185271; 23670308; 23701949; 23811271 very low density lipoprotein receptor Alzpathway: VLDLR-APOE association. Source: https://pubmed.ncbi.nlm.nih.gov/28292942/ Ensembl:ENSG00000147852 HGNC:12698 HPRD:01895 MIM:192977 Vega:OTTHUMG00000019447 VLDLR Bin Zhao, Yue Liu, Oliver He BMND16 INT1 OI15 WEB: http://www.ncbi.nlm.nih.gov/gene WNT1 wingless-type MMTV integration site family, member 1 7471 12q13 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000578 (EC: ISS); GO_0001658 (EC: IEA); GO_0001934 (EC: IEA); GO_0005109 (EC: IBA); GO_0005109 (EC: IC, PMID: 19756656); GO_0005125 (EC: ISS); GO_0005576 (EC: TAS); GO_0005578 (EC: IEA); GO_0005615 (EC: IBA); GO_0005737 (EC: IDA, PMID: 11793365); GO_0005788 (EC: TAS); GO_0005796 (EC: TAS); GO_0005886 (EC: TAS); GO_0007267 (EC: ISS); GO_0007520 (EC: IEA); GO_0008284 (EC: IDA, PMID: 16501043); GO_0008284 (EC: IMP, PMID: 19778454); GO_0009611 (EC: IEP, PMID: 17982423); GO_0009986 (EC: IEA); GO_0010592 (EC: IMP, PMID: 19756656); GO_0010812 (EC: IDA, PMID: 16501043); GO_0016055 (EC: IDA, PMID: 10644691); GO_0019904 (EC: IEA); GO_0021527 (EC: IEA); GO_0021536 (EC: IEA); GO_0021551 (EC: ISS); GO_0021588 (EC: ISS); GO_0021797 (EC: IEA); GO_0022004 (EC: IEA); GO_0022408 (EC: IMP, PMID: 17072303); GO_0030182 (EC: IBA); GO_0030512 (EC: IEA); GO_0030514 (EC: IMP, PMID: 16194878); GO_0030579 (EC: IEA); GO_0030901 (EC: ISS); GO_0031100 (EC: IEA); GO_0033077 (EC: IEA); GO_0042472 (EC: IEA); GO_0042770 (EC: IDA, PMID: 16501043); GO_0043568 (EC: IDA, PMID: 12154096); GO_0044212 (EC: IDA, PMID: 19847889); GO_0044336 (EC: IMP, PMID: 12154096); GO_0045165 (EC: IBA); GO_0045599 (EC: ISS); GO_0045747 (EC: IDA, PMID: 16501043); GO_0045893 (EC: IDA, PMID: 10644691); GO_0045893 (EC: IMP, PMID: 19847889); GO_0045893 (EC: ISS); GO_0045944 (EC: IEA); GO_0048018 (EC: IC, PMID: 19778454); GO_0048146 (EC: IMP, PMID: 19734317); GO_0048664 (EC: IEA); GO_0051091 (EC: ISS); GO_0060061 (EC: ISS); GO_0060070 (EC: IMP, PMID: 19756656); GO_0060348 (EC: IMP); GO_0061184 (EC: IDA, PMID: 10654605); GO_0070365 (EC: IEA); GO_0071375 (EC: IEA); GO_0071425 (EC: IEA); GO_0090344 (EC: IDA, PMID: 16501043); GO_2000059 (EC: IEA) PMID: 2202907; 2534596; 2998762; 3281802; 3329717; 9147651; 10347172; 10511339; 10557084; 10644691; 10654605; 10866835; 11029007; 11336703; 11350055; 11448771; 11782388; 11793365; 11832495; 12014624; 12154096; 12209999; 12477932; 14644163; 14960582; 15149841; 15194563; 15454084; 15489334; 15580286; 15592430; 15824740; 15841445; 15913453; 16194878; 16329837; 16427602; 16474850; 16495219; 16501043; 16565090; 16756720; 16760136; 16930536; 17035233; 17072303; 17143299; 17289346; 17306035; 17875805; 17947472; 17982423; 18056036; 18059186; 18097596; 18187620; 18218837; 18297060; 18461473; 18469861; 18562274; 18593917; 18636547; 18676739; 18705344; 18762249; 18769115; 18769117; 18790633; 18824543; 18838960; 18844223; 18936100; 19061838; 19148501; 19174556; 19349579; 19398721; 19401692; 19448422; 19453261; 19473496; 19628668; 19693690; 19711366; 19729480; 19734317; 19756656; 19778454; 19781444; 19847889; 19885602; 19924227; 19956716; 19956832; 20334650; 20491588; 20564229; 20664938; 20809334; 20865400; 21044957; 21259057; 21317455; 21321190; 21336184; 21344486; 21505183; 21678109; 21680704; 21781302; 21851818; 21858154; 21971039; 22117039; 22123293; 22139084; 22270359; 22351518; 22388478; 22391424; 22392999; 22406377; 22494971; 22546285; 22696217; 22815884; 22823957; 22859293; 22954590; 23134367; 23152495; 23284750; 23379509; 23434763; 23499309; 23499310; 23551536; 23613467; 23656646; 23851184; 23913826; 24067880; 24305876; 24374807 wingless-type MMTV integration site family, member 1 HGNC:12774 HPRD:01276 MIM:164820 WNT1 Bin Zhao, Yue Liu, Oliver He hWNT5A WEB: http://www.ncbi.nlm.nih.gov/gene WNT5A wingless-type MMTV integration site family, member 5A 7474 3p21-p14 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000187 (EC: IDA); GO_0001667 (EC: IEA); GO_0001736 (EC: IEA); GO_0001756 (EC: IEA); GO_0001837 (EC: IEP, PMID: 12841867); GO_0001843 (EC: IEA); GO_0001938 (EC: IMP, PMID: 17986384); GO_0001947 (EC: IEA); GO_0002053 (EC: IEA); GO_0002088 (EC: ISS, PMID: 16258938); GO_0002741 (EC: IMP, PMID: 18174455); GO_0003323 (EC: IEA); GO_0003408 (EC: ISS, PMID: 16258938); GO_0003700 (EC: IMP, PMID: 19847889); GO_0005109 (EC: IPI, PMID: 18174455); GO_0005110 (EC: IEA); GO_0005115 (EC: IPI, PMID: 18287027); GO_0005125 (EC: IEA); GO_0005576 (EC: TAS); GO_0005578 (EC: IEA); GO_0005615 (EC: IDA, PMID: 18703641); GO_0005788 (EC: TAS); GO_0005796 (EC: TAS); GO_0005886 (EC: TAS); GO_0006468 (EC: IEA); GO_0007223 (EC: IDA, PMID: 19946729); GO_0007223 (EC: IMP, PMID: 17986384); GO_0007257 (EC: IDA); GO_0007257 (EC: IMP); GO_0007411 (EC: ISS); GO_0007442 (EC: IEA); GO_0007494 (EC: IEA); GO_0008584 (EC: IEP, PMID: 17848411); GO_0008595 (EC: IEA); GO_0009986 (EC: IEA); GO_0010033 (EC: IEP, PMID: 17486081); GO_0010595 (EC: IMP, PMID: 17035633); GO_0010800 (EC: IEA); GO_0010820 (EC: IMP, PMID: 19520808); GO_0010976 (EC: ISS); GO_0016055 (EC: IDA); GO_0019904 (EC: IEA); GO_0021891 (EC: ISS); GO_0030182 (EC: IBA); GO_0030182 (EC: ISS); GO_0030216 (EC: IEP, PMID: 19399181); GO_0030324 (EC: IEA); GO_0030514 (EC: IEA); GO_0030669 (EC: TAS); GO_0030825 (EC: IDA, PMID: 19946729); GO_0032148 (EC: IDA); GO_0032729 (EC: IEA); GO_0032755 (EC: IMP, PMID: 18174455); GO_0033138 (EC: IEA); GO_0034613 (EC: IDA, PMID: 19177143); GO_0036342 (EC: IEA); GO_0038031 (EC: IEA); GO_0040037 (EC: IEA); GO_0042060 (EC: IDA, PMID: 19878652); GO_0042733 (EC: IEA); GO_0043032 (EC: IMP, PMID: 18174455); GO_0043066 (EC: IDA, PMID: 19251946); GO_0044212 (EC: IDA, PMID: 19847889); GO_0045080 (EC: IMP, PMID: 19520808); GO_0045165 (EC: IBA); GO_0045599 (EC: IMP); GO_0045732 (EC: IGI, PMID: 12952940); GO_0045766 (EC: IMP, PMID: 17035633); GO_0045778 (EC: IMP); GO_0045836 (EC: IEA); GO_0045892 (EC: IDA, PMID: 19277043); GO_0045893 (EC: IMP, PMID: 19847889); GO_0045944 (EC: IMP, PMID: 18174455); GO_0046330 (EC: IEA); GO_0048018 (EC: IC, PMID: 18174455); GO_0048146 (EC: IDA, PMID: 19251946); GO_0048706 (EC: IMP, PMID: 19918918); GO_0048806 (EC: IMP, PMID: 19918918); GO_0048843 (EC: IEA); GO_0048850 (EC: IEA); GO_0050680 (EC: IEA); GO_0050718 (EC: IMP, PMID: 18174455); GO_0050729 (EC: IMP, PMID: 18174455); GO_0050919 (EC: IEA); GO_0051092 (EC: IDA, PMID: 18287027); GO_0051216 (EC: IEA); GO_0051964 (EC: IEA); GO_0060021 (EC: IMP, PMID: 18413325); GO_0060029 (EC: IEA); GO_0060065 (EC: IEA); GO_0060067 (EC: IEA); GO_0060068 (EC: IEA); GO_0060070 (EC: IEA); GO_0060157 (EC: IEA); GO_0060324 (EC: IMP, PMID: 19918918); GO_0060340 (EC: IDA, PMID: 19399181); GO_0060599 (EC: IEA); GO_0060638 (EC: IEA); GO_0060686 (EC: IEA); GO_0060744 (EC: IEA); GO_0060750 (EC: IEA); GO_0060760 (EC: IDA, PMID: 19399181); GO_0060762 (EC: IEA); GO_0060907 (EC: IMP, PMID: 18174455); GO_0061036 (EC: IEA); GO_0061347 (EC: IEA); GO_0061348 (EC: IEA); GO_0061349 (EC: IEA); GO_0061350 (EC: IEA); GO_0061354 (EC: IEA); GO_0070062 (EC: TAS); GO_0070245 (EC: IEA); GO_0071222 (EC: IEP, PMID: 18174455); GO_0071277 (EC: IEP, PMID: 18703641); GO_0071300 (EC: ISS); GO_0071346 (EC: IEP, PMID: 18174455); GO_0071425 (EC: IDA, PMID: 9787155); GO_0071542 (EC: IEA); GO_0071560 (EC: IEP, PMID: 15040835); GO_0072201 (EC: IDA, PMID: 19878652); GO_0090009 (EC: IEA); GO_0090037 (EC: IMP, PMID: 19099253); GO_0090090 (EC: IDA, PMID: 17976063); GO_0090090 (EC: IGI, PMID: 12952940); GO_0090103 (EC: IEA); GO_0090179 (EC: IEA); GO_2000049 (EC: IEA); GO_2000484 (EC: IEA) PMID: 8167409; 8288227; 8537388; 8889548; 9054360; 9787155; 10491302; 10557084; 11956659; 12086864; 12165812; 12244165; 12477932; 12482967; 12805222; 12839624; 12841867; 12952940; 14702039; 15040835; 15067324; 15389636; 15588944; 15592517; 15735754; 16169547; 16258938; 16344560; 16569699; 16601243; 16880514; 16914445; 16996564; 17035633; 17227781; 17426020; 17458904; 17463182; 17486081; 17525119; 17546602; 17709179; 17848411; 17937436; 17952396; 17956663; 17967789; 17976063; 17986384; 17992121; 18032022; 18172252; 18174174; 18174455; 18287027; 18413325; 18420933; 18456733; 18462958; 18477650; 18541964; 18615587; 18632632; 18656562; 18703641; 18794093; 18990694; 19048125; 19061910; 19063862; 19074888; 19099253; 19148501; 19171330; 19177143; 19244247; 19251946; 19277043; 19399181; 19453261; 19467340; 19473452; 19492056; 19520808; 19561643; 19582886; 19651774; 19696445; 19760930; 19802008; 19847889; 19849855; 19874313; 19878652; 19910923; 19918918; 19940551; 19946729; 19956879; 20008136; 20032469; 20083703; 20101234; 20376066; 20379614; 20429785; 20454608; 20518933; 20525402; 20554957; 20603606; 20628624; 20634891; 20639201; 20890934; 20955350; 21069266; 21115903; 21165581; 21205070; 21209903; 21270611; 21285942; 21342370; 21344486; 21352264; 21365928; 21431850; 21461571; 21587258; 21672426; 21816908; 21871017; 21918189; 21963094; 21980498; 22039506; 22101459; 22124122; 22128168; 22162112; 22293903; 22384081; 22384249; 22485170; 22493546; 22547701; 22609948; 22655072; 22694338; 22781592; 22825874; 23001722; 23046419; 23054609; 23075330; 23159080; 23178630; 23254341; 23265959; 23266365; 23271023; 23278988; 23342259; 23349696; 23353182; 23359789; 23396967; 23417837; 23462101; 23469623; 23484019; 23615002; 23660959; 23679576; 23716599; 23764752; 23963164; 24091015; 24250222 wingless-type MMTV integration site family, member 5A Ensembl:ENSG00000114251 HGNC:12784 HPRD:01293 MIM:164975 Vega:OTTHUMG00000158361 WNT5A Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene WNT7A wingless-type MMTV integration site family, member 7A 7476 3p25 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000578 (EC: IMP, PMID: 16826533); GO_0001502 (EC: IDA, PMID: 17202865); GO_0002062 (EC: IDA, PMID: 17202865); GO_0005102 (EC: IPI, PMID: 12857724); GO_0005109 (EC: IBA); GO_0005125 (EC: IDA, PMID: 18986540); GO_0005576 (EC: TAS); GO_0005578 (EC: IEA); GO_0005615 (EC: IBA); GO_0005788 (EC: TAS); GO_0005796 (EC: TAS); GO_0005886 (EC: TAS); GO_0007269 (EC: IEA); GO_0007548 (EC: TAS, PMID: 9790192); GO_0008105 (EC: IEA); GO_0009953 (EC: IEA); GO_0009986 (EC: IEA); GO_0014719 (EC: IEA); GO_0014834 (EC: IEA); GO_0021707 (EC: IEA); GO_0021846 (EC: IDA, PMID: 12843296); GO_0022009 (EC: IEA); GO_0030010 (EC: IEA); GO_0030182 (EC: IBA); GO_0031133 (EC: IEA); GO_0032355 (EC: IEA); GO_0035115 (EC: IMP, PMID: 16826533); GO_0035116 (EC: IMP, PMID: 16826533); GO_0035567 (EC: IEA); GO_0035659 (EC: IDA, PMID: 15802269); GO_0042733 (EC: IMP, PMID: 16826533); GO_0043066 (EC: IEA); GO_0045165 (EC: IBA); GO_0045893 (EC: IDA, PMID: 15802269); GO_0045944 (EC: IDA, PMID: 12857724); GO_0046330 (EC: IBA); GO_0048018 (EC: IC, PMID: 15802269); GO_0048018 (EC: IDA, PMID: 18986540); GO_0048103 (EC: IEA); GO_0048864 (EC: IDA, PMID: 12843296); GO_0050768 (EC: IDA, PMID: 12843296); GO_0050808 (EC: IEA); GO_0051965 (EC: IDA, PMID: 18986540); GO_0060021 (EC: IMP, PMID: 18413325); GO_0060054 (EC: IDA, PMID: 15802269); GO_0060066 (EC: IEA); GO_0060070 (EC: IDA, PMID: 12857724); GO_0061038 (EC: IEA); GO_0070307 (EC: ISS, PMID: 16258938); GO_0071560 (EC: IEP, PMID: 15040835); GO_0090263 (EC: IEA) PMID: 8167409; 8168088; 8893824; 9161407; 9790192; 11070089; 11232041; 11784006; 12477932; 12843296; 12857724; 12893825; 12937339; 14550385; 15040835; 15082716; 15705594; 15802269; 16169070; 16258938; 16826533; 16835228; 17201809; 17202865; 17588571; 18230341; 18413325; 18538017; 18606951; 18986540; 19054571; 19159115; 19171330; 19453261; 19849868; 20083228; 20219685; 20379614; 20470940; 20501643; 20503388; 20709709; 20845993; 20949531; 21271649; 21344627; 22177312; 22232518; 22294752; 22403725; 22987443; 23056560; 23144326; 23321718; 23727605 wingless-type MMTV integration site family, member 7A WNT7A Bin Zhao, Yue Liu, Oliver He TREB5 XBP-1 XBP2 WEB: http://www.ncbi.nlm.nih.gov/gene XBP1 X-box binding protein 1 7494 22q12.1|22q12 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0003677 (EC: TAS, PMID: 1718857); GO_0003700 (EC: IEA); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0006366 (EC: IEA); GO_0006955 (EC: TAS, PMID: 1718857); GO_0006987 (EC: TAS); GO_0030968 (EC: TAS); GO_0031017 (EC: IEA); GO_0042493 (EC: IEA); GO_0043565 (EC: IEA); GO_0044267 (EC: TAS); GO_0051602 (EC: IEA); GO_0060096 (EC: IEA); GO_0060691 (EC: IEA); GO_0071236 (EC: IEA); GO_1900103 (EC: IMP, PMID: 16645094) PMID: 1718857; 1903538; 2196176; 2321018; 8349596; 8657566; 9563853; 10591208; 10652269; 11076863; 11256614; 11779464; 11813207; 12067985; 12477932; 12586069; 12713871; 12805554; 12949534; 12954762; 14576841; 14634507; 14702039; 15063770; 15149721; 15184063; 15298659; 15331160; 15351732; 15380296; 15461802; 15489334; 15489336; 15598891; 15882996; 15892135; 15927087; 15936534; 16002735; 16009131; 16154272; 16342282; 16381901; 16461360; 16645094; 16958950; 17026957; 17034899; 17092596; 17418411; 17442311; 17660348; 17884689; 17898050; 17906960; 17928342; 17932454; 18082745; 18191223; 18192112; 18386815; 18417469; 18552212; 18583979; 18635891; 18676680; 18775308; 18840095; 18840627; 19009018; 19122331; 19154631; 19170196; 19176362; 19237300; 19265690; 19321437; 19380033; 19389935; 19403667; 19412428; 19416856; 19420237; 19435892; 19470730; 19471022; 19530237; 19543371; 19564049; 19622636; 19625176; 19669932; 19692168; 19722195; 19735688; 19751410; 19941857; 19958799; 20013084; 20170659; 20211142; 20368688; 20421453; 20688044; 20955178; 20980528; 21050047; 21061914; 21085187; 21129256; 21129257; 21138464; 21138840; 21233347; 21385877; 21423203; 21660045; 21693764; 21858728; 21906983; 21924241; 21963094; 22002058; 22370484; 22427205; 22445760; 22469468; 22505724; 22644804; 22669460; 22679299; 22787145; 22925926; 22960999; 23184933; 23277279; 23335490; 23421912; 23447676; 23470653; 23510626; 23560553; 23661758; 23737521; 24027308; 24029229; 24165480 X-box binding protein 1 Ensembl:ENSG00000100219 HGNC:12801 HPRD:01908 MIM:194355 Vega:OTTHUMG00000151094 XBP1 Bin Zhao, Yue Liu, Oliver He SRK STCD STD TZK ZAP-70 WEB: http://www.ncbi.nlm.nih.gov/gene ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 2q12 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0001772 (EC: IEA); GO_0001784 (EC: IEA); GO_0002250 (EC: TAS); GO_0004713 (EC: IDA, PMID: 12447358); GO_0004713 (EC: NAS, PMID: 1423621); GO_0004713 (EC: TAS); GO_0004715 (EC: TAS); GO_0005515 (EC: IPI, PMID: 10318843); GO_0005524 (EC: NAS, PMID: 1423621); GO_0005737 (EC: TAS, PMID: 12359715); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 12150984); GO_0005886 (EC: TAS); GO_0006468 (EC: IDA, PMID: 12447358); GO_0006468 (EC: NAS, PMID: 1423621); GO_0006955 (EC: IDA, PMID: 1423621); GO_0018108 (EC: IDA); GO_0030217 (EC: NAS, PMID: 8613493); GO_0035556 (EC: NAS, PMID: 1423621); GO_0042101 (EC: IDA, PMID: 8176201); GO_0042110 (EC: TAS); GO_0042113 (EC: TAS); GO_0043366 (EC: IEA); GO_0045059 (EC: IDA, PMID: 7630421); GO_0045060 (EC: IEA); GO_0045121 (EC: IDA, Qualifier: colocalizes_with, PMID: 12150984); GO_0045582 (EC: IDA, PMID: 7630421); GO_0046638 (EC: IEA); GO_0046641 (EC: IEA); GO_0046777 (EC: IEA); GO_0050850 (EC: IEA); GO_0050852 (EC: TAS); GO_0070489 (EC: TAS); GO_0072678 (EC: TAS) PMID: 1423621; 7522245; 7528772; 7539035; 7629168; 7630421; 7737297; 7760813; 7761456; 7798261; 7819147; 7961936; 8082894; 8176201; 8202712; 8202713; 8366117; 8530437; 8613493; 8621646; 8638162; 8702662; 8756661; 8761298; 8798643; 8906806; 8943371; 9036949; 9047237; 9169414; 9269777; 9362531; 9378960; 9403695; 9407100; 9464824; 9490415; 9685404; 9698567; 9846481; 9988730; 10037717; 10074432; 10078535; 10209036; 10221598; 10318843; 10419455; 10449770; 10458769; 10660534; 10779765; 10790433; 10867021; 10966114; 10979964; 11048639; 11133830; 11279207; 11353765; 11368773; 11390470; 11412303; 11572860; 11781312; 11855827; 11891219; 11964272; 11976341; 12051764; 12084069; 12150984; 12154360; 12165490; 12186560; 12190313; 12359715; 12387734; 12393534; 12447358; 12450381; 12477932; 12504004; 12522270; 12595313; 12646565; 12648457; 12778467; 12817019; 12847255; 14523017; 14557276; 14560012; 14672952; 14766232; 14985102; 15059847; 15084271; 15100278; 15133473; 15143214; 15144186; 15190462; 15292186; 15358536; 15370248; 15489334; 15514014; 15536084; 15588985; 15592455; 15688026; 15699074; 15735648; 15759031; 15800671; 15856008; 15861514; 15923611; 15972449; 15996927; 16079094; 16079107; 16094384; 16096284; 16219325; 16263570; 16273093; 16291755; 16300468; 16339550; 16406604; 16412387; 16418492; 16461343; 16467082; 16467851; 16503409; 16538501; 16642047; 16823829; 16888650; 16906159; 16932341; 17038529; 17051526; 17192257; 17215865; 17222799; 17375875; 17492476; 17512407; 17534928; 17577788; 17652306; 17702857; 17767948; 17785822; 17926183; 17931624; 17948236; 18005690; 18022252; 18025306; 18029348; 18048647; 18190465; 18203013; 18311544; 18322442; 18333847; 18424730; 18453590; 18519230; 18577710; 18616755; 18683785; 18687687; 18689273; 18757853; 18770822; 18770856; 18818202; 18854088; 19018007; 19021053; 19050243; 19136305; 19230824; 19267204; 19297020; 19298946; 19377082; 19454010; 19575876; 19679010; 19710135; 19727816; 19826250; 19907441; 19920178; 19944462; 20001236; 20014315; 20029467; 20056178; 20132303; 20145264; 20164537; 20228263; 20301777; 20488542; 20534575; 20575031; 20637659; 20657554; 20702582; 20842205; 20864151; 20890395; 21055809; 21079155; 21200022; 21205967; 21344162; 21453975; 21463115; 21607290; 21716207; 21725281; 21832049; 21856938; 21887278; 21945028; 21988832; 22002134; 22151263; 22171799; 22207134; 22266821; 22338471; 22362302; 22505724; 22564988; 22664044; 22802418; 22839722; 22844345; 22888118; 22965421; 22971532; 22984268; 23097993; 23124046; 23245794; 23267066; 23293025; 23406209; 23514740; 23530057; 23572149; 23620790; 23786282; 23916875; 23981382; 24103478; 24219331 zeta-chain (TCR) associated protein kinase 70kDa Ensembl:ENSG00000115085 HGNC:12858 HPRD:01495 MIM:176947 Vega:OTTHUMG00000153060 ZAP70 Bin Zhao, Yue Liu, Oliver He BMZF-2 BMZF2 KOX22 ZNF255 ZNF27 WEB: http://www.ncbi.nlm.nih.gov/gene ZNF224 zinc finger protein 224 7767 19q13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0003677 (EC: IEA); GO_0003700 (EC: IBA); GO_0005515 (EC: IPI); GO_0005634 (EC: IDA); GO_0006351 (EC: IEA); GO_0017053 (EC: IDA); GO_0031965 (EC: IDA); GO_0045892 (EC: IDA); GO_0046872 (EC: IEA) PMID: 2288909; 10585455; 12239212; 12477932; 12527367; 12743021; 15302935; 15489334; 15576338; 16150558; 16344560; 17900823; 19118814; 19505435; 19741270; 20379614; 20574532; 20587513; 20591825; 21187159; 23362234 zinc finger protein 224 Ensembl:ENSG00000267680 HGNC:13017 HPRD:06094 MIM:194555 Vega:OTTHUMG00000182313 ZNF224 Bin Zhao, Yue Liu, Oliver He APOER2 HSZ75190 LRP-8 MCI1 WEB: http://www.ncbi.nlm.nih.gov/gene LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 7804 RP5-1024G6.8 1p34 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000122 (EC: ISS); GO_0001523 (EC: TAS); GO_0004888 (EC: TAS, PMID: 8626535); GO_0005509 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12950167); GO_0005576 (EC: IEA); GO_0005875 (EC: IEA); GO_0005886 (EC: TAS); GO_0005901 (EC: IDA, PMID: 11369809); GO_0006508 (EC: NAS, PMID: 11152697); GO_0006629 (EC: NAS, PMID: 11152697); GO_0006897 (EC: IDA, PMID: 8626535); GO_0006898 (EC: IDA, PMID: 8626535); GO_0007165 (EC: TAS, PMID: 10380922); GO_0007596 (EC: TAS); GO_0007603 (EC: TAS); GO_0008035 (EC: IEA); GO_0014069 (EC: IEA); GO_0016021 (EC: IC, PMID: 11152697); GO_0019221 (EC: NAS, PMID: 11152697); GO_0019894 (EC: IEA); GO_0021541 (EC: ISS); GO_0021819 (EC: IEA); GO_0030229 (EC: IDA, PMID: 8626535); GO_0030425 (EC: IEA); GO_0032793 (EC: ISS); GO_0034185 (EC: IC, PMID: 8626535); GO_0038025 (EC: ISS); GO_0038026 (EC: ISS); GO_0042493 (EC: IEA); GO_0043025 (EC: IEA); GO_0043235 (EC: IDA); GO_0050731 (EC: ISS); GO_0050804 (EC: ISS); GO_0061003 (EC: ISS); GO_0061098 (EC: ISS); GO_0071363 (EC: IEA); GO_0071397 (EC: IEA); GO_1900006 (EC: ISS) PMID: 8626535; 9079678; 10218790; 10231386; 10380922; 10508213; 10571240; 10827173; 11152697; 11369809; 12167620; 12169628; 12399018; 12426372; 12477932; 12621059; 12670700; 12681505; 12807892; 12824284; 12871934; 12899622; 12950167; 14702039; 14732905; 15313836; 15459198; 15489334; 15950758; 16034672; 16332682; 16481437; 16642433; 16951405; 17470198; 17614163; 17847002; 18039658; 18089558; 18489431; 18592168; 19056482; 19116273; 19282863; 19439088; 19661487; 19720620; 19913121; 19948739; 20208369; 20331378; 20493228; 20628086; 21157031; 21316997; 21347244; 21554715; 21601501; 21906983; 21963094; 22109552; 22170052; 22404453; 22419519; 22589174; 22889673; 23192594; 23524007; 23739027 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor Alzpathway: LRP8-APOE association. Source: https://pubmed.ncbi.nlm.nih.gov/17428983/ HGNC:6700 HPRD:04002 MIM:602600 LRP8 Bin Zhao, Yue Liu, Oliver He CD184 D2S201E FB22 HM89 HSY3RR LAP3 LCR1 LESTR NPY3R NPYR NPYRL NPYY3R WHIM WEB: http://www.ncbi.nlm.nih.gov/gene CXCR4 chemokine (C-X-C motif) receptor 4 7852 2q21 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0000187 (EC: TAS, PMID: 10570282); GO_0001569 (EC: IEA); GO_0001618 (EC: IEA); GO_0001666 (EC: IEP, PMID: 15174142); GO_0001667 (EC: IEA); GO_0001764 (EC: IEA); GO_0002407 (EC: TAS, PMID: 16621978); GO_0003779 (EC: IDA, PMID: 12421915); GO_0004930 (EC: TAS, PMID: 8276799); GO_0005515 (EC: IPI, PMID: 10644702); GO_0005737 (EC: TAS, PMID: 10415069); GO_0005764 (EC: IDA); GO_0005769 (EC: IDA); GO_0005770 (EC: IDA); GO_0005886 (EC: IDA); GO_0005886 (EC: TAS); GO_0006915 (EC: TAS, PMID: 10942389); GO_0006954 (EC: TAS, PMID: 8276799); GO_0007186 (EC: IDA, PMID: 10644702); GO_0007204 (EC: TAS, PMID: 10228019); GO_0007281 (EC: IEA); GO_0007420 (EC: IEA); GO_0008045 (EC: IEA); GO_0008354 (EC: IEA); GO_0009615 (EC: TAS, PMID: 10583963); GO_0009897 (EC: IEA); GO_0009986 (EC: IDA, PMID: 10521508); GO_0015026 (EC: TAS, PMID: 10754293); GO_0016021 (EC: IEA); GO_0016023 (EC: IDA, PMID: 19106094); GO_0016032 (EC: TAS); GO_0016494 (EC: NAS, PMID: 9468539); GO_0019722 (EC: IMP, PMID: 19064997); GO_0019955 (EC: IEA); GO_0030054 (EC: IEA); GO_0030260 (EC: TAS); GO_0030334 (EC: IEA); GO_0030426 (EC: IEA); GO_0031252 (EC: IDA, PMID: 12421915); GO_0031410 (EC: IDA, PMID: 10521508); GO_0031625 (EC: IPI, PMID: 19116316); GO_0032027 (EC: IDA, PMID: 12421915); GO_0042098 (EC: IEA); GO_0042119 (EC: IEA); GO_0043130 (EC: IDA); GO_0043217 (EC: ISS); GO_0048714 (EC: ISS); GO_0050920 (EC: IMP, PMID: 19106094); GO_0061351 (EC: IEA); GO_0070062 (EC: IDA); GO_0070098 (EC: NAS, PMID: 9468539); GO_0071345 (EC: IDA) PMID: 1187744; 2834384; 7505609; 7592830; 8234909; 8276799; 8325644; 8329116; 8629022; 8640552; 8674119; 8752280; 8752281; 8805353; 8849450; 8898753; 8929542; 8976200; 8995603; 9020356; 9024623; 9031325; 9151868; 9184207; 9261451; 9300725; 9302439; 9359702; 9362541; 9379028; 9461627; 9468539; 9499113; 9499115; 9599023; 9600268; 9601645; 9614108; 9632631; 9634237; 9634238; 9653051; 9653130; 9658081; 9696823; 9710449; 9721247; 9736741; 9744279; 9765440; 9770524; 9780207; 9826718; 9879064; 9882290; 9933168; 9973525; 10029247; 10074122; 10089882; 10228019; 10229873; 10233851; 10329539; 10339592; 10357469; 10358157; 10364484; 10370370; 10371171; 10393923; 10393974; 10415069; 10430052; 10438703; 10438870; 10446313; 10449282; 10452968; 10480633; 10482576; 10487781; 10505675; 10506573; 10521508; 10544150; 10555208; 10559349; 10570282; 10582593; 10583963; 10585143; 10590105; 10590121; 10600606; 10602722; 10623764; 10644702; 10651866; 10669334; 10704341; 10738970; 10754293; 10756055; 10758170; 10772939; 10801487; 10802710; 10816381; 10825158; 10860877; 10864687; 10875613; 10877489; 10903911; 10903920; 10941932; 10942389; 11005830; 11024154; 11027346; 11069996; 11086073; 11115360; 11118068; 11119612; 11141237; 11153675; 11157475; 11162626; 11162839; 11175286; 11264367; 11265761; 11278278; 11278567; 11313374; 11333905; 11342415; 11356952; 11356967; 11390582; 11390601; 11397808; 11408611; 11413305; 11414813; 11426226; 11462036; 11464139; 11468147; 11489906; 11517394; 11529558; 11533159; 11551942; 11559423; 11591141; 11591370; 11595336; 11602639; 11602715; 11641392; 11668182; 11679153; 11689632; 11693435; 11698270; 11709091; 11711593; 11711617; 11751889; 11752220; 11799176; 11861874; 11867624; 11876757; 11877445; 11878912; 11880384; 11912162; 11920324; 11929756; 11931835; 11937572; 11953881; 11983855; 11994484; 11994538; 12004084; 12034737; 12091904; 12093918; 12163560; 12171912; 12193696; 12208881; 12218052; 12239139; 12239174; 12351385; 12354773; 12355376; 12356205; 12368305; 12368322; 12370187; 12388552; 12393569; 12393663; 12421915; 12429730; 12433920; 12477874; 12477932; 12485835; 12488503; 12490404; 12499259; 12502809; 12519755; 12519884; 12531874; 12551992; 12555203; 12555204; 12586555; 12605695; 12609846; 12634405; 12651900; 12690099; 12692554; 12705474; 12713058; 12726730; 12730102; 12761880; 12766157; 12775414; 12783211; 12791666; 12832058; 12834106; 12843275; 12853157; 12857973; 12871111; 12873764; 12873765; 12882655; 12882661; 12894851; 12927045; 12960231; 12963807; 13679920; 14505910; 14555820; 14567988; 14576059; 14592831; 14595012; 14597738; 14602072; 14630801; 14640682; 14672331; 14684377; 14688392; 14694113; 14715575; 14764445; 14973260; 14982745; 14988150; 14990703; 14990729; 14995074; 15019705; 15026622; 15033669; 15033938; 15047829; 15048928; 15054042; 15113900; 15117454; 15123627; 15128813; 15161081; 15169555; 15174142; 15180966; 15183061; 15184910; 15201990; 15225616; 15235108; 15251986; 15258189; 15279544; 15308751; 15327899; 15328152; 15328206; 15351504; 15358596; 15363550; 15377464; 15452229; 15454484; 15467730; 15479838; 15486895; 15489334; 15492752; 15509740; 15536192; 15540205; 15542430; 15548713; 15548717; 15549771; 15585097; 15585836; 15588345; 15598422; 15608062; 15615703; 15618472; 15632118; 15650174; 15660419; 15662133; 15670831; 15681827; 15687242; 15701832; 15705741; 15710459; 15719026; 15737629; 15748209; 15753377; 15781337; 15784966; 15787642; 15794931; 15802268; 15805285; 15806155; 15814634; 15819887; 15831676; 15843590; 15844659; 15857508; 15867478; 15880586; 15890935; 15972662; 15992849; 15995960; 15998835; 16005638; 16044003; 16047221; 16084492; 16114056; 16172123; 16179731; 16188969; 16204649; 16227248; 16230077; 16236267; 16284526; 16306611; 16322285; 16327980; 16365278; 16368946; 16375941; 16378977; 16467205; 16489019; 16494043; 16494621; 16524887; 16528367; 16585856; 16618732; 16621978; 16631222; 16638848; 16675573; 16679918; 16697675; 16702010; 16740704; 16756721; 16756955; 16784459; 16802356; 16823836; 16836911; 16841089; 16863915; 16877302; 16886061; 16888620; 16919488; 16928758; 16929169; 16929176; 16942785; 16943240; 16946301; 16948134; 16948905; 16966601; 16969502; 16978607; 16987062; 16990599; 17010165; 17011204; 17023512; 17032700; 17038674; 17056591; 17070589; 17075975; 17077324; 17082613; 17119115; 17121788; 17130833; 17136117; 17176471; 17188679; 17198877; 17202224; 17251291; 17253948; 17262717; 17327270; 17328229; 17328838; 17329448; 17331556; 17346946; 17350297; 17355795; 17379424; 17411375; 17435771; 17456315; 17457084; 17459055; 17461449; 17476338; 17488655; 17504381; 17507467; 17507486; 17510563; 17521613; 17545018; 17559806; 17562613; 17574038; 17582634; 17594938; 17596666; 17606439; 17620369; 17634424; 17640743; 17641542; 17650669; 17676665; 17687643; 17706641; 17715128; 17715399; 17763975; 17765649; 17768666; 17846797; 17875700; 17881971; 17888880; 17889832; 17893878; 17894415; 17895991; 17916907; 17925864; 17947233; 17947541; 17959679; 17964871; 17977968; 17991743; 18036244; 18037996; 18040858; 18081034; 18083706; 18087217; 18089812; 18097955; 18155192; 18175225; 18182005; 18187620; 18190699; 18200497; 18201276; 18206727; 18210030; 18219852; 18234887; 18235009; 18239145; 18240029; 18242797; 18267010; 18274673; 18281050; 18286257; 18288973; 18292939; 18334485; 18337451; 18339860; 18339870; 18353956; 18357387; 18365549; 18373506; 18416455; 18431597; 18438604; 18443596; 18448868; 18461161; 18468560; 18480460; 18487224; 18500445; 18502034; 18511598; 18519809; 18524826; 18556411; 18562079; 18568019; 18570923; 18577758; 18593989; 18599607; 18624931; 18632580; 18634924; 18636124; 18653785; 18692524; 18696160; 18698020; 18701133; 18707241; 18753930; 18760838; 18760839; 18765807; 18769446; 18775311; 18781098; 18784079; 18788547; 18798091; 18799424; 18803056; 18807177; 18808680; 18812968; 18815295; 18820725; 18829537; 18834145; 18836306; 18851783; 18923649; 18925934; 18948617; 18949410; 18954561; 18957686; 18958626; 18976975; 18977142; 18991615; 19002187; 19008040; 19017998; 19019622; 19020538; 19020745; 19025611; 19035451; 19042019; 19053768; 19057930; 19064997; 19066282; 19074885; 19082444; 19106094; 19107931; 19113880; 19115008; 19116316; 19125297; 19134328; 19136936; 19139298; 19147814; 19148483; 19149577; 19178925; 19196101; 19199057; 19200444; 19212630; 19228923; 19232661; 19240061; 19252530; 19260802; 19272813; 19297481; 19302975; 19305148; 19327121; 19335218; 19336475; 19336886; 19339951; 19339953; 19340288; 19351212; 19352387; 19366992; 19373784; 19379572; 19379577; 19379578; 19391039; 19414793; 19433312; 19438749; 19449444; 19460858; 19472013; 19473177; 19476565; 19492159; 19494283; 19496172; 19497995; 19513547; 19513623; 19520808; 19521120; 19523923; 19525448; 19525953; 19526283; 19540208; 19550128; 19551455; 19563077; 19567784; 19568410; 19570110; 19580679; 19584257; 19588204; 19593633; 19605489; 19615218; 19615279; 19654311; 19665027; 19671192; 19688824; 19692474; 19703720; 19716197; 19730683; 19731977; 19735481; 19761697; 19762327; 19765831; 19769961; 19774645; 19784070; 19796655; 19812192; 19812382; 19816083; 19816596; 19820417; 19825996; 19830694; 19837984; 19859817; 19879194; 19885584; 19906780; 19912363; 19913121; 19921580; 19923906; 19932585; 19950235; 19956569; 20007689; 20018238; 20023696; 20025867; 20028517; 20035824; 20036848; 20048153; 20051874; 20053635; 20067991; 20068066; 20071457; 20084476; 20102637; 20109310; 20118565; 20133817; 20134207; 20141446; 20154716; 20159979; 20177796; 20196768; 20206813; 20228059; 20338046; 20349215; 20380698; 20386750; 20388788; 20388803; 20421499; 20439195; 20450430; 20460402; 20462600; 20465832; 20484957; 20492653; 20502526; 20505072; 20525755; 20540706; 20561415; 20563655; 20568229; 20573729; 20573813; 20578990; 20580677; 20585037; 20594270; 20594957; 20598333; 20599766; 20603605; 20607251; 20616219; 20622011; 20628086; 20629312; 20629629; 20637871; 20646340; 20646838; 20651371; 20660740; 20661303; 20661426; 20699000; 20705717; 20708218; 20710056; 20722038; 20723431; 20728717; 20801883; 20802527; 20829512; 20842205; 20847314; 20859707; 20861157; 20861743; 20865359; 20876529; 20921899; 20923564; 20929726; 20953377; 20956518; 20972812; 21048156; 21052687; 21059341; 21070597; 21071054; 21076047; 21080209; 21082982; 21087342; 21087446; 21093051; 21110890; 21127401; 21138752; 21139054; 21152581; 21156016; 21158728; 21178277; 21186999; 21188555; 21205837; 21238532; 21264298; 21292343; 21295814; 21300944; 21304904; 21312239; 21321123; 21349176; 21349998; 21350711; 21357602; 21381021; 21402361; 21435112; 21447649; 21454012; 21459858; 21463876; 21468602; 21506920; 21513481; 21518481; 21521526; 21525208; 21527066; 21530075; 21537329; 21553525; 21555814; 21567400; 21569409; 21573951; 21607621; 21607655; 21618080; 21623238; 21623830; 21624427; 21627959; 21630055; 21631268; 21633638; 21655198; 21655330; 21656184; 21668366; 21670103; 21676905; 21680174; 21695171; 21705626; 21720384; 21723943; 21728385; 21730065; 21731496; 21738044; 21740294; 21757744; 21760891; 21802105; 21802140; 21818756; 21831961; 21835796; 21878648; 21887463; 21890473; 21906588; 21906874; 21909080; 21909361; 21931863; 21934106; 21948620; 21951552; 21963094; 21969820; 21985848; 21986127; 21987572; 21988832; 22018245; 22023092; 22025564; 22039044; 22052462; 22074556; 22075627; 22084248; 22101518; 22103833; 22103834; 22114110; 22133596; 22152016; 22157596; 22169254; 22169298; 22175768; 22200669; 22220212; 22220905; 22226668; 22232208; 22238325; 22242160; 22245379; 22253872; 22266857; 22266861; 22275353; 22292949; 22297516; 22299827; 22313935; 22333149; 22342838; 22359577; 22362916; 22366438; 22370645; 22370717; 22377565; 22427920; 22427929; 22430135; 22450749; 22463589; 22471472; 22472349; 22479424; 22490156; 22495096; 22496149; 22496601; 22505724; 22526457; 22532631; 22537596; 22541097; 22547906; 22549810; 22554649; 22568557; 22582975; 22596258; 22634622; 22644306; 22645275; 22657741; 22683307; 22688512; 22689289; 22699677; 22706111; 22727731; 22728273; 22732432; 22745793; 22767589; 22779681; 22784557; 22802411; 22808111; 22830600; 22847686; 22848341; 22852142; 22871210; 22885527; 22902648; 22908191; 22914607; 22916293; 22923991; 22925564; 22932666; 22936065; 22941282; 22952422; 22954962; 22987307; 22995914; 23023480; 23039915; 23046610; 23053994; 23075330; 23082154; 23133664; 23148226; 23160836; 23177198; 23197643; 23216236; 23219524; 23223005; 23223950; 23231927; 23244336; 23259294; 23263827; 23279723; 23288365; 23321466; 23326587; 23331013; 23344887; 23349771; 23395387; 23421710; 23434321; 23443279; 23468933; 23469143; 23472069; 23472074; 23490053; 23495012; 23497290; 23497377; 23526079; 23528817; 23544621; 23555768; 23563306; 23565284; 23591873; 23609324; 23623275; 23647548; 23659571; 23669361; 23676502; 23688427; 23697661; 23702796; 23710557; 23714687; 23726130; 23728080; 23734232; 23744460; 23744532; 23754844; 23758411; 23765204; 23769877; 23773022; 23777983; 23794067; 23798675; 23802178; 23827153; 23845465; 23849988; 23856897; 23865743; 23886194; 23895705; 23911867; 23918302; 23924922; 23925152; 23935395; 23936528; 23954894; 23966000; 24005135; 24023356; 24032722; 24052640; 24091662; 24101523; 24157575; 24174685; 24184476; 24239175; 24489825 chemokine (C-X-C motif) receptor 4 Ensembl:ENSG00000121966 HGNC:2561 HPRD:01217 MIM:162643 Vega:OTTHUMG00000153583 CXCR4 Bin Zhao, Yue Liu, Oliver He CALM CLTH LAP WEB: http://www.ncbi.nlm.nih.gov/gene PICALM phosphatidylinositol binding clathrin assembly protein 8301 11q14 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 16491119); GO_0005545 (EC: ISS); GO_0005634 (EC: IDA, PMID: 16491119); GO_0005794 (EC: IEA); GO_0005905 (EC: IDA, PMID: 10436022); GO_0005905 (EC: ISS); GO_0006461 (EC: TAS, PMID: 8643484); GO_0006898 (EC: IDA, PMID: 10436022); GO_0006898 (EC: ISS); GO_0007409 (EC: IEA); GO_0016192 (EC: TAS, PMID: 8643484); GO_0016197 (EC: IMP, PMID: 16262731); GO_0030097 (EC: IEA); GO_0030100 (EC: IMP, PMID: 18182011); GO_0030122 (EC: IDA, Qualifier: colocalizes_with, PMID: 16262731); GO_0030132 (EC: IDA, Qualifier: colocalizes_with, PMID: 10436022); GO_0030276 (EC: IDA, PMID: 10436022); GO_0030276 (EC: ISS); GO_0031623 (EC: IMP, PMID: 14985334); GO_0032050 (EC: IDA, PMID: 10436022); GO_0032880 (EC: IDA, PMID: 10436022); GO_0042734 (EC: ISS); GO_0043231 (EC: IDA); GO_0045211 (EC: ISS); GO_0045893 (EC: IDA, PMID: 11425879); GO_0048261 (EC: IDA, PMID: 10436022); GO_0048268 (EC: IMP, PMID: 16262731); GO_0048471 (EC: ISS, Qualifier: colocalizes_with); GO_0048813 (EC: IEA) PMID: 1547942; 8643484; 9737689; 10436022; 10926122; 11425879; 12461747; 12477932; 14702039; 14985334; 15146197; 15182197; 15489334; 16262731; 16491119; 17097559; 17170719; 17597474; 17804713; 18029348; 18037964; 18074379; 18094714; 18182011; 19450545; 19734902; 19738201; 20460622; 20534741; 20554627; 20558387; 20570404; 20674675; 20697030; 20738160; 20739100; 20838239; 20951388; 21059989; 21139048; 21220176; 21221849; 21297266; 21300948; 21347408; 21358043; 21460841; 21627779; 21706055; 21890473; 21906983; 21912625; 21963094; 21965661; 21987572; 21988832; 22015308; 22064352; 22402018; 22539346; 22539578; 22558309; 22623428; 22639918; 22715855; 22832961; 22888099; 22889924; 22939629; 22943764; 22952074; 22975751; 23040034; 23382074; 23487024; 23572399; 23601808; 23650005; 23670296; 23741335; 23870418; 24067654; 24076290 phosphatidylinositol binding clathrin assembly protein Ensembl:ENSG00000073921 HGNC:15514 HPRD:04320 MIM:603025 Vega:OTTHUMG00000166981 PICALM Bin Zhao, Yue Liu, Oliver He AXIN PPP1R49 WEB: http://www.ncbi.nlm.nih.gov/gene AXIN1 axin 1 8312 LA16c-314G4.3 16p13.3 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0000209 (EC: IEA); GO_0001701 (EC: IEA); GO_0001743 (EC: IBA); GO_0001934 (EC: IDA, PMID: 9601641); GO_0004871 (EC: IDA, PMID: 9601641); GO_0005096 (EC: IBA); GO_0005102 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10644691); GO_0005634 (EC: IDA, PMID: 12072559); GO_0005737 (EC: IDA, PMID: 12072559); GO_0005794 (EC: IEA); GO_0005829 (EC: TAS); GO_0005881 (EC: IBA); GO_0005938 (EC: IBA); GO_0006913 (EC: IEA); GO_0006915 (EC: IEA); GO_0007257 (EC: IBA); GO_0007368 (EC: IBA); GO_0007605 (EC: IEA); GO_0008013 (EC: IDA, PMID: 10644691); GO_0008022 (EC: IEA); GO_0008219 (EC: IBA); GO_0009950 (EC: IBA); GO_0010800 (EC: NAS, PMID: 18593713); GO_0014069 (EC: IBA); GO_0016023 (EC: IBA); GO_0016328 (EC: IDA, PMID: 12072559); GO_0019899 (EC: IPI, PMID: 19759537); GO_0019901 (EC: IBA); GO_0019901 (EC: ISS); GO_0021797 (EC: IBA); GO_0021881 (EC: IBA); GO_0030163 (EC: IEA); GO_0030178 (EC: IDA, PMID: 10644691); GO_0030511 (EC: IEA); GO_0030877 (EC: IDA, PMID: 16188939); GO_0030910 (EC: IBA); GO_0031122 (EC: IBA); GO_0031398 (EC: NAS, PMID: 18593713); GO_0031410 (EC: ISS); GO_0031625 (EC: IPI, PMID: 16601693); GO_0032147 (EC: IDA, PMID: 9601641); GO_0032436 (EC: IEA); GO_0032947 (EC: IDA, PMID: 9601641); GO_0032947 (EC: IMP, PMID: 16601693); GO_0033138 (EC: NAS, PMID: 18593713); GO_0034244 (EC: IEA); GO_0035412 (EC: IBA); GO_0036342 (EC: IEA); GO_0038032 (EC: IEA); GO_0042802 (EC: ISS); GO_0042803 (EC: ISS); GO_0043547 (EC: IBA); GO_0043621 (EC: IEA); GO_0043623 (EC: IDA, PMID: 16601693); GO_0045599 (EC: IBA); GO_0045732 (EC: IC, PMID: 16188939); GO_0045732 (EC: IDA, PMID: 9601641); GO_0045893 (EC: IMP, PMID: 16601693); GO_0046330 (EC: ISS); GO_0046332 (EC: IPI, PMID: 18593713); GO_0048048 (EC: IBA); GO_0048320 (EC: IBA); GO_0048471 (EC: IDA, PMID: 19038973); GO_0051248 (EC: IEA); GO_0051260 (EC: IEA); GO_0051443 (EC: IMP, PMID: 16601693); GO_0055001 (EC: IBA); GO_0060070 (EC: IC, PMID: 9601641); GO_0060272 (EC: IBA); GO_0060823 (EC: IBA); GO_0070016 (EC: IBA); GO_0070016 (EC: ISS); GO_0070411 (EC: IPI, PMID: 16601693); GO_0070412 (EC: IEA); GO_0071407 (EC: IBA); GO_0071514 (EC: IEA); GO_0071944 (EC: IDA, PMID: 19038973); GO_0090090 (EC: IBA); GO_0090244 (EC: IBA); GO_2000060 (EC: ISS) PMID: 9054936; 9230313; 9335612; 9482734; 9601641; 9734785; 9920888; 10228155; 10330403; 10428961; 10488109; 10581160; 10644691; 10698523; 10700176; 10811618; 10829020; 11157797; 11297546; 11336703; 11438668; 11487578; 11557983; 11719457; 11809808; 11884395; 11955436; 11997515; 12000790; 12036951; 12072559; 12101426; 12138115; 12192039; 12209999; 12223491; 12417018; 12421363; 12477932; 12511557; 12554650; 12555076; 12556519; 12584189; 12717450; 12771989; 12805222; 12820959; 12883680; 12897152; 14534723; 14566817; 14630927; 14970870; 15063782; 15064706; 15262978; 15327769; 15355978; 15489334; 15520370; 15526030; 15579909; 15616553; 15698401; 15981102; 16163548; 16169070; 16188939; 16199882; 16293619; 16601693; 16753179; 16772034; 16773576; 16868183; 16890161; 17018282; 17143297; 17210684; 17318175; 17353931; 17418091; 17510365; 17569865; 17588722; 17720811; 17768662; 18171349; 18330950; 18514389; 18593713; 18632848; 18708403; 18762581; 19038973; 19107203; 19131971; 19141611; 19202075; 19249679; 19303846; 19331826; 19390532; 19453261; 19513548; 19582507; 19633924; 19731416; 19759537; 19778269; 19913121; 20098615; 20122174; 20128690; 20379614; 20531388; 20628086; 20844743; 20846493; 20858899; 21057547; 21087614; 21242974; 21383061; 21478859; 21502811; 21648318; 21769465; 21795712; 21799911; 21808024; 21902576; 21988832; 22234612; 22270359; 22504420; 22509369; 22524844; 22613765; 22614067; 22682247; 22933777; 23110995; 23192643; 23277359; 23278310; 23455922; 23525311; 23602568; 23671587; 23826318; 23879168; 23915259; 23959799; 24011952 axin 1 Ensembl:ENSG00000103126 HGNC:903 HPRD:04819 MIM:603816 Vega:OTTHUMG00000064930 AXIN1 Bin Zhao, Yue Liu, Oliver He AXIL ODCRCS WEB: http://www.ncbi.nlm.nih.gov/gene AXIN2 axin 2 8313 17q23-q24 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0001934 (EC: IMP); GO_0001957 (EC: IBA); GO_0003413 (EC: IEA); GO_0004871 (EC: IEA); GO_0005096 (EC: IBA); GO_0005515 (EC: IPI, PMID: 10698523); GO_0005634 (EC: IDA, PMID: 12072559); GO_0005737 (EC: IDA); GO_0005813 (EC: IDA); GO_0005881 (EC: IBA); GO_0005886 (EC: IBA); GO_0005938 (EC: IBA); GO_0008013 (EC: IBA); GO_0008013 (EC: NAS, PMID: 11017067); GO_0008283 (EC: IEA); GO_0008285 (EC: IMP, PMID: 16247484); GO_0009950 (EC: IBA); GO_0010718 (EC: IMP, PMID: 17072303); GO_0010942 (EC: IMP, PMID: 16247484); GO_0014069 (EC: IBA); GO_0016023 (EC: IBA); GO_0019899 (EC: IPI, PMID: 19759537); GO_0019901 (EC: IBA); GO_0030282 (EC: IEA); GO_0030877 (EC: NAS, PMID: 11017067); GO_0031625 (EC: IPI); GO_0032423 (EC: IMP, PMID: 11017067); GO_0034613 (EC: IDA, PMID: 17072303); GO_0035414 (EC: IMP, PMID: 11017067); GO_0038032 (EC: IEA); GO_0042476 (EC: IMP, PMID: 15042511); GO_0043547 (EC: IBA); GO_0043570 (EC: IMP, PMID: 18755497); GO_0045668 (EC: IBA); GO_0048255 (EC: IMP, PMID: 17072303); GO_0061181 (EC: IEA); GO_0070016 (EC: IBA); GO_0070411 (EC: IEA); GO_0070602 (EC: IMP); GO_0071407 (EC: IBA); GO_0090090 (EC: IDA, PMID: 11940574); GO_0090090 (EC: IMP, PMID: 11017067); GO_0090244 (EC: IBA) PMID: 8889548; 9566905; 10021369; 10049590; 10647780; 10698523; 10966653; 11017067; 11438668; 11474173; 11940574; 12072559; 12183362; 12477932; 15042511; 15304487; 15489334; 15611123; 15766563; 16247484; 16344560; 16432638; 16601693; 16820935; 16941501; 17002498; 17072303; 17143297; 17373666; 17927870; 18330950; 18372914; 18384130; 18676680; 18683894; 18708403; 18755497; 18790474; 19065536; 19119171; 19170196; 19270026; 19336002; 19584075; 19623616; 19625176; 19692168; 19759537; 19816326; 19888426; 20056645; 20128690; 20219685; 20300119; 20403997; 20453000; 20508983; 20613673; 20635389; 20844743; 21069480; 21294210; 21383061; 21541676; 21626677; 21666490; 21706018; 21733995; 21799911; 21890473; 22322943; 22370446; 22745173; 22887353; 23169889; 23393221; 23455922; 23516639; 23602568; 23624843 axin 2 Ensembl:ENSG00000168646 HGNC:904 HPRD:04935 MIM:604025 Vega:OTTHUMG00000179353 AXIN2 Bin Zhao, Yue Liu, Oliver He ATG1 ATG1A UNC51 Unc51.1 hATG1 WEB: http://www.ncbi.nlm.nih.gov/gene ULK1 unc-51 like autophagy activating kinase 1 8408 12q24.3 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000045 (EC: IEA); GO_0004674 (EC: IDA, PMID: 18936157); GO_0004674 (EC: NAS, PMID: 9693035); GO_0005515 (EC: IPI, PMID: 11146101); GO_0005524 (EC: IEA); GO_0005737 (EC: NAS, PMID: 9693035); GO_0005776 (EC: IDA, PMID: 17595159); GO_0005829 (EC: IDA, PMID: 11146101); GO_0006468 (EC: NAS, PMID: 9693035); GO_0007265 (EC: IEA); GO_0008104 (EC: IMP, PMID: 16940348); GO_0010506 (EC: IDA, PMID: 18936157); GO_0010506 (EC: IMP, PMID: 17595159); GO_0010508 (EC: ISS); GO_0016239 (EC: IMP); GO_0017137 (EC: IPI); GO_0019901 (EC: IEA); GO_0021707 (EC: IEA); GO_0021933 (EC: IEA); GO_0030659 (EC: IEA); GO_0031102 (EC: IEA); GO_0031175 (EC: IMP, PMID: 18007665); GO_0031623 (EC: IEA); GO_0031669 (EC: ISS); GO_0032403 (EC: IPI, PMID: 19211835); GO_0034045 (EC: IDA, PMID: 18936157); GO_0042594 (EC: ISS); GO_0043005 (EC: IEA); GO_0043025 (EC: IEA); GO_0046777 (EC: IDA, PMID: 18936157); GO_0048671 (EC: IEA); GO_0048675 (EC: IEA); GO_0051386 (EC: IEA); GO_0070969 (EC: IPI, PMID: 19211835) PMID: 8889548; 9693035; 9872452; 11076863; 11146101; 12477932; 14702039; 15014045; 16940348; 17081983; 17192257; 17353931; 17595159; 18007665; 18936157; 19211835; 19225151; 19258318; 19287211; 19690328; 20562859; 20921139; 21072212; 21205641; 21258367; 21460630; 21460634; 21475306; 21518141; 21560199; 21795849; 21819378; 22321011; 22539723; 22585231; 22613832; 22885598; 23027865; 23043107; 23078367; 23291726; 23455922; 23524951; 23716696; 23863160; 24119841 unc-51 like autophagy activating kinase 1 Ensembl:ENSG00000177169 HGNC:12558 HPRD:11933 MIM:603168 Vega:OTTHUMG00000168052 ULK1 Bin Zhao, Yue Liu, Oliver He HRNT1 O-GLCNAC WEB: http://www.ncbi.nlm.nih.gov/gene OGT O-linked N-acetylglucosamine (GlcNAc) transferase 8473 Xq13 20140408 9606 X protein-coding Official from a nomenclature committee GO_0000123 (EC: IDA); GO_0005515 (EC: IPI, PMID: 12150998); GO_0005547 (EC: IDA, PMID: 18288188); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005739 (EC: IEA); GO_0005815 (EC: IDA); GO_0005829 (EC: IDA); GO_0005886 (EC: IDA); GO_0006110 (EC: IDA); GO_0006325 (EC: TAS); GO_0006493 (EC: IDA); GO_0006493 (EC: IMP); GO_0006915 (EC: IDA); GO_0007165 (EC: TAS, PMID: 9083067); GO_0007584 (EC: TAS, PMID: 9083068); GO_0008047 (EC: IDA); GO_0008375 (EC: TAS, PMID: 9083068); GO_0016262 (EC: IDA); GO_0030854 (EC: IMP); GO_0031397 (EC: ISS); GO_0032868 (EC: IDA, PMID: 18288188); GO_0032922 (EC: ISS); GO_0035020 (EC: IDA, PMID: 18288188); GO_0043085 (EC: IDA); GO_0043981 (EC: IDA); GO_0043982 (EC: IDA); GO_0043984 (EC: IDA); GO_0043995 (EC: IDA, Qualifier: contributes_to); GO_0043996 (EC: IDA, Qualifier: contributes_to); GO_0045862 (EC: IDA); GO_0045944 (EC: IDA); GO_0045944 (EC: IMP); GO_0046626 (EC: IDA, PMID: 18288188); GO_0046972 (EC: IDA, Qualifier: contributes_to); GO_0048015 (EC: IDA, PMID: 18288188); GO_0051571 (EC: IDA); GO_0061087 (EC: IMP); GO_0070688 (EC: IDA); GO_0071300 (EC: IMP); GO_0080182 (EC: IMP); GO_0090526 (EC: ISS); GO_0097363 (EC: ISS) PMID: 1512232; 1533623; 1730617; 7642555; 8063760; 8076819; 8344946; 8619474; 8639509; 8702840; 8910513; 9083067; 9083068; 9110174; 9343410; 9499386; 10386995; 10580430; 10753899; 10801981; 11773972; 11846551; 12136128; 12150998; 12226704; 12373287; 12435728; 12477932; 12504895; 12538765; 12670868; 12724313; 12911634; 14601650; 15336570; 15489334; 15561949; 15795231; 15896326; 16105839; 16189514; 16344560; 16434389; 16449650; 16505006; 16966374; 17000644; 17353931; 17882263; 18029348; 18174169; 18288188; 18536723; 18653473; 18781797; 19073609; 19615732; 19932102; 20068230; 20190804; 20200153; 20206135; 20360068; 20479123; 20628624; 20805223; 20805357; 20824293; 20845477; 20876116; 21081666; 21139048; 21240259; 21252943; 21285374; 21295698; 21327254; 21567137; 21890473; 21906983; 21963094; 21987572; 22053931; 22072767; 22275356; 22294689; 22307082; 22311971; 22371499; 22384635; 22496241; 22505724; 22574218; 22783592; 22863883; 22883232; 22939629; 23000965; 23088713; 23103939; 23103942; 23152511; 23184937; 23222540; 23246001; 23487789; 23642195; 23700425; 23720054; 24256146; 24311690 O-linked N-acetylglucosamine (GlcNAc) transferase Ensembl:ENSG00000147162 HGNC:8127 HPRD:02222 MIM:300255 Vega:OTTHUMG00000033316 OGT Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene GALR3 galanin receptor 3 8484 22q13.1 20140408 9606 22 protein-coding Official from a nomenclature committee GO_0004966 (EC: IEA); GO_0005886 (EC: TAS); GO_0007193 (EC: IEA); GO_0007194 (EC: IEA); GO_0007218 (EC: TAS, PMID: 9722565); GO_0007268 (EC: TAS, PMID: 9722565); GO_0007611 (EC: TAS, PMID: 9722565); GO_0007631 (EC: TAS, PMID: 9722565); GO_0016021 (EC: IEA) PMID: 2834384; 9722565; 9832121; 9928159; 10441207; 10591208; 11867941; 17083333; 18577758; 19086053; 20398908; 20677014; 20817064; 20848231; 22889491 galanin receptor 3 GALR3 Bin Zhao, Yue Liu, Oliver He KAT1 WEB: http://www.ncbi.nlm.nih.gov/gene HAT1 histone acetyltransferase 1 8520 2q31.2-q33.1 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0004402 (EC: IEA); GO_0005515 (EC: IPI, PMID: 19862764); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IEA); GO_0006323 (EC: TAS, PMID: 9427644); GO_0006325 (EC: TAS); GO_0006348 (EC: IEA); GO_0006475 (EC: TAS, PMID: 9427644); GO_0007584 (EC: IEA); GO_0016363 (EC: IEA); GO_0043231 (EC: IDA) PMID: 9427644; 10911985; 11329013; 11492997; 11585814; 12408818; 12477932; 12775419; 14718166; 15161933; 15489334; 15815621; 16344560; 17052979; 17081983; 17207965; 17609381; 18029348; 18458078; 18781797; 19410544; 19615732; 19815555; 19862764; 20080577; 20224553; 20504901; 20562859; 20639865; 20953179; 21139048; 21145461; 21890473; 21906983; 21963094; 21987572; 22053931; 22190034; 22228774; 22505724; 22615379; 22797925; 22863883; 22939629; 22990118; 23000965; 23281010; 23653357; 24116224 histone acetyltransferase 1 Ensembl:ENSG00000128708 HGNC:4821 HPRD:04339 MIM:603053 Vega:OTTHUMG00000132282 HAT1 Bin Zhao, Yue Liu, Oliver He CAGH39 CAMGUK CMG FGS4 LIN2 MICPCH MRXSNA TNRC8 WEB: http://www.ncbi.nlm.nih.gov/gene CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 8573 RP11-540L11.1 Xp11.4 20140408 9606 X protein-coding Official from a nomenclature committee GO_0001953 (EC: IMP, PMID: 18664494); GO_0004385 (EC: TAS, PMID: 9660868); GO_0004674 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11377421); GO_0005516 (EC: IEA); GO_0005524 (EC: IEA); GO_0005604 (EC: IDA, Qualifier: colocalizes_with, PMID: 18664494); GO_0005652 (EC: IDA, PMID: 18664494); GO_0005730 (EC: IDA, PMID: 18664494); GO_0005737 (EC: IDA, PMID: 18664494); GO_0005829 (EC: IEA); GO_0005886 (EC: TAS, PMID: 9660868); GO_0005911 (EC: IDA, PMID: 18664494); GO_0007155 (EC: TAS, PMID: 9660868); GO_0010839 (EC: IMP, PMID: 18664494); GO_0015629 (EC: TAS, PMID: 9660868); GO_0016323 (EC: IEA); GO_0016363 (EC: IDA, PMID: 18664494); GO_0030198 (EC: TAS); GO_0042043 (EC: IEA); GO_0042734 (EC: ISS); GO_0045944 (EC: IEA); GO_0046939 (EC: TAS, PMID: 9660868); GO_0060170 (EC: ISS); GO_0061045 (EC: IMP, PMID: 18664494); GO_0070509 (EC: IEA); GO_0090280 (EC: IEA); GO_0090288 (EC: IMP, PMID: 18664494) PMID: 8786425; 9225980; 9546224; 9660868; 9660869; 9722958; 9753324; 9822620; 9952408; 10455105; 10460248; 10749215; 10856295; 10993877; 11003712; 11036064; 11120739; 11356864; 11377421; 11679592; 11742811; 11880184; 12006486; 12040031; 12093160; 12110687; 12151521; 12151522; 12202822; 12351654; 12477932; 12511555; 12522552; 12641734; 12676536; 14627983; 14702039; 14960569; 15024025; 15066269; 15123239; 15231748; 15331416; 15673434; 15694377; 15729360; 16637659; 16688213; 16842202; 17287346; 18423203; 18629876; 18664494; 19019082; 19125693; 19165920; 19200522; 19322201; 19523119; 19615732; 19736351; 19781660; 19847910; 20006588; 20029458; 20623620; 21139048; 21590270; 21735175; 21763699; 21855798; 21890473; 21906983; 21954287; 21988832; 22389404; 22452838; 22709267; 23165780; 23406872; 23600800; 23602568; 23864692; 24250222; 24278995 calcium/calmodulin-dependent serine protein kinase (MAGUK family) Ensembl:ENSG00000147044 HGNC:1497 HPRD:02164 MIM:300172 Vega:OTTHUMG00000021378 CASK Bin Zhao, Yue Liu, Oliver He CGB-PDE CN5A PDE5 WEB: http://www.ncbi.nlm.nih.gov/gene PDE5A phosphodiesterase 5A, cGMP-specific 8654 4q27 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0004114 (EC: NAS, PMID: 9714779); GO_0005575 (EC: ND); GO_0005829 (EC: TAS); GO_0007165 (EC: IEA); GO_0007596 (EC: TAS); GO_0010613 (EC: IEA); GO_0030553 (EC: TAS, PMID: 15938621); GO_0042130 (EC: IEA); GO_0043406 (EC: IEA); GO_0046069 (EC: IDA, PMID: 14687666); GO_0046069 (EC: IEA); GO_0046872 (EC: IEA); GO_0047555 (EC: IEA); GO_0055118 (EC: IEA); GO_0055119 (EC: IEA); GO_0060282 (EC: IEA) PMID: 2168396; 8557689; 8889548; 9115850; 9642111; 9714779; 9716380; 10393044; 10411650; 10679249; 10679255; 10859452; 11076863; 11162575; 11230166; 11358813; 11602184; 11896473; 12359732; 12477932; 12554648; 12604588; 12650945; 12955149; 14668322; 14687666; 14764637; 15093609; 15175637; 15240816; 15489334; 15489336; 15640438; 15817798; 15938621; 16381901; 16407275; 16690614; 17017938; 17138653; 17906676; 18029348; 18293931; 18635550; 18757735; 19139381; 19852267; 19961855; 19996273; 20177899; 20196613; 20308615; 20332099; 20332439; 20346360; 20351714; 20379614; 20491634; 20553468; 20555034; 20563733; 20590607; 20595799; 20861010; 21193396; 21215707; 21421555; 21425347; 21505183; 21525805; 21697861; 21736695; 21890473; 21987443; 22843873; 22960860; 23033484; 23527037 phosphodiesterase 5A, cGMP-specific Ensembl:ENSG00000138735 HGNC:8784 HPRD:04497 MIM:603310 Vega:OTTHUMG00000132971 PDE5A Bin Zhao, Yue Liu, Oliver He IRS-2 WEB: http://www.ncbi.nlm.nih.gov/gene IRS2 insulin receptor substrate 2 8660 13q34 20140408 9606 13 protein-coding Official from a nomenclature committee GO_0002053 (EC: IEA); GO_0002903 (EC: ISS); GO_0004871 (EC: IEA); GO_0005158 (EC: IEA); GO_0005515 (EC: IPI, PMID: 17901049); GO_0005829 (EC: TAS); GO_0005886 (EC: TAS); GO_0006006 (EC: TAS, PMID: 9495343); GO_0007165 (EC: TAS, PMID: 7675087); GO_0007173 (EC: TAS); GO_0007420 (EC: IEA); GO_0008283 (EC: IEA); GO_0008284 (EC: NAS, PMID: 17925406); GO_0008286 (EC: ISS); GO_0008286 (EC: TAS); GO_0008543 (EC: TAS); GO_0009749 (EC: ISS); GO_0010748 (EC: IMP, PMID: 16814735); GO_0010907 (EC: IMP, PMID: 16814735); GO_0019216 (EC: TAS, PMID: 16814735); GO_0019901 (EC: IEA); GO_0019903 (EC: IEA); GO_0019904 (EC: IEA); GO_0030335 (EC: IEA); GO_0030879 (EC: IEA); GO_0030890 (EC: ISS); GO_0032000 (EC: IMP, PMID: 16814735); GO_0032024 (EC: ISS); GO_0032869 (EC: IMP, PMID: 16814735); GO_0033673 (EC: ISS); GO_0038095 (EC: TAS); GO_0043548 (EC: IEA); GO_0045087 (EC: TAS); GO_0045725 (EC: IMP, PMID: 16814735); GO_0045725 (EC: NAS, PMID: 17925406); GO_0046326 (EC: IMP, PMID: 16814735); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS); GO_0055088 (EC: TAS, PMID: 16814735); GO_0060397 (EC: TAS); GO_0071333 (EC: IEA); GO_0071889 (EC: IEA) PMID: 7499365; 7559579; 7675087; 7876077; 8550573; 8621590; 8626379; 8662806; 8732688; 8910607; 8938433; 8954948; 9113989; 9195949; 9295312; 9312143; 9334184; 9495343; 9535722; 9609109; 9648831; 9651339; 9651378; 9852124; 10077005; 10417350; 10480623; 10594015; 10679027; 10856136; 11030756; 11054408; 11147812; 11481324; 11505033; 11522686; 11600548; 11641236; 11872698; 11912194; 12052866; 12107746; 12167717; 12189449; 12198247; 12213887; 12228220; 12379806; 12475767; 12477932; 12493740; 12519871; 12554758; 12660731; 12687350; 12732844; 12765968; 12783867; 12821935; 12933652; 12960006; 14534541; 14604996; 14653106; 14978080; 15057823; 15123681; 15127203; 15155816; 15161933; 15247132; 15292987; 15302935; 15308584; 15316008; 15324660; 15514089; 15588985; 15678496; 15778465; 15811564; 15926113; 15940190; 16030120; 16086274; 16127164; 16150916; 16448675; 16489531; 16652127; 16814735; 16839840; 16964243; 17030631; 17051426; 17068339; 17081983; 17222321; 17353931; 17361103; 17374994; 17416760; 17898946; 17901049; 17914103; 17925406; 17979178; 18059035; 18079194; 18271526; 18506362; 18611262; 18660489; 18802016; 18992263; 19038974; 19109239; 19124510; 19190347; 19259821; 19322201; 19332049; 19377890; 19447894; 19509476; 19561084; 19604268; 19690174; 19755487; 19818665; 19875459; 19878940; 19887537; 19913121; 19926323; 19929986; 20092705; 20184486; 20210696; 20354165; 20416077; 20416304; 20628086; 20634197; 20685959; 21042750; 21045156; 21258861; 21325637; 21340542; 21693764; 21700708; 21706016; 21771880; 21777391; 21801267; 21852217; 21890473; 21933986; 21984580; 22147666; 22205343; 22287730; 22465474; 22523112; 22623531; 22844442; 22912850; 22939629; 22974441; 22994406; 23018177; 23049845; 23147115; 23216712; 23251408; 23594372; 23617393; 23706954; 24255178; 24616100 insulin receptor substrate 2 Ensembl:ENSG00000185950 HGNC:6126 HPRD:02878 MIM:600797 Vega:OTTHUMG00000017338 IRS2 Bin Zhao, Yue Liu, Oliver He ATG6 VPS30 beclin1 WEB: http://www.ncbi.nlm.nih.gov/gene BECN1 beclin 1, autophagy related 8678 17q21 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000045 (EC: IEA); GO_0000910 (EC: IMP); GO_0001666 (EC: IEA); GO_0005515 (EC: IPI, PMID: 16417406); GO_0005634 (EC: IEA); GO_0005794 (EC: IEA); GO_0005802 (EC: IEA); GO_0006968 (EC: TAS, PMID: 9765397); GO_0007040 (EC: IEA); GO_0008285 (EC: IEA); GO_0016020 (EC: IEA); GO_0016023 (EC: IEA); GO_0016032 (EC: IEA); GO_0016239 (EC: IEA); GO_0030425 (EC: IEA); GO_0033197 (EC: IEA); GO_0042493 (EC: IEA); GO_0043066 (EC: TAS, PMID: 9765397); GO_0043234 (EC: IEA); GO_0048666 (EC: IEA); GO_0050435 (EC: IEA); GO_0051607 (EC: IEA); GO_0071275 (EC: IEA); GO_0071364 (EC: IEA) PMID: 7490091; 7829101; 8125298; 9765397; 10395800; 10604474; 11306555; 11309306; 11564866; 12372286; 12477932; 14966907; 14970205; 15489334; 15922724; 16267277; 16390869; 16417406; 16522639; 16713569; 16718815; 16857678; 16874027; 17203225; 17236580; 17272502; 17337444; 17355787; 17438366; 17441324; 17441338; 17446862; 17550384; 17589504; 17595761; 17643073; 17659302; 17786023; 17999086; 18005679; 18184403; 18184459; 18497881; 18497889; 18552835; 18628207; 18641390; 18769161; 18797192; 18829541; 18843052; 19050071; 19060920; 19066461; 19130303; 19145109; 19180116; 19218137; 19270693; 19270696; 19289499; 19298526; 19298604; 19318089; 19325567; 19347031; 19372752; 19375507; 19395874; 19520853; 19535901; 19535919; 19556884; 19635843; 19641499; 19680556; 19713971; 19762066; 19778902; 19798108; 19921231; 20004946; 20009549; 20010695; 20023428; 20037818; 20090905; 20150769; 20190558; 20206246; 20207475; 20230646; 20368806; 20454448; 20473282; 20501938; 20559548; 20562859; 20638385; 20639699; 20643123; 20697744; 20842118; 20863706; 20889974; 20921139; 20937944; 21081164; 21203962; 21209283; 21239722; 21327823; 21353614; 21358617; 21420796; 21444671; 21478185; 21499230; 21537144; 21543763; 21556768; 21610315; 21646862; 21654208; 21681342; 21711108; 21722286; 21729531; 21750416; 21769915; 21777947; 21779982; 21861179; 21873141; 21875280; 21890473; 21906983; 21936852; 21962518; 21971985; 21976705; 22039439; 22081109; 22095667; 22147978; 22157765; 22174682; 22219388; 22240664; 22242123; 22248718; 22286270; 22301112; 22310240; 22314358; 22335943; 22392728; 22393062; 22493499; 22498477; 22622204; 22627130; 22648564; 22650021; 22674982; 22733132; 22742832; 22797916; 22805532; 22875631; 22933281; 23029344; 23089287; 23112296; 23125008; 23184933; 23197835; 23216071; 23225331; 23264393; 23316280; 23334926; 23337876; 23420005; 23429496; 23444126; 23478334; 23479509; 23504944; 23525201; 23564079; 23569248; 23573264; 23703612; 23722017; 23737459; 23801739; 23812859; 23827971; 23877263; 23878393; 23935917; 23943370; 23974797; 24012002; 24034250; 24056301; 24141421; 24186908; 24324106; 24345332 beclin 1, autophagy related Ensembl:ENSG00000126581 HGNC:1034 HPRD:05087 MIM:604378 Vega:OTTHUMG00000180653 BECN1 Bin Zhao, Yue Liu, Oliver He SCARA2 WEB: http://www.ncbi.nlm.nih.gov/gene MARCO macrophage receptor with collagenous structure 8685 2q14.2 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0002221 (EC: TAS, PMID: 10331948); GO_0004888 (EC: TAS, PMID: 10331948); GO_0005044 (EC: IEA); GO_0005581 (EC: IEA); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 9468508); GO_0007166 (EC: TAS, PMID: 9468508); GO_0008329 (EC: TAS, PMID: 10331948); GO_0030666 (EC: TAS); GO_0043277 (EC: IEA); GO_0045087 (EC: IEA) PMID: 7867067; 9468508; 10331948; 10651831; 11315932; 11820786; 12097327; 12444143; 12477932; 12847263; 15489334; 16237101; 16335952; 19240061; 19403625; 20237496; 20810988; 21299846; 21886847; 21986627; 22470185; 22470186; 23154236; 23249958; 23617307; 23739639 macrophage receptor with collagenous structure Ensembl:ENSG00000019169 HGNC:6895 HPRD:05337 MIM:604870 Vega:OTTHUMG00000131400 MARCO Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene TNK1 tyrosine kinase, non-receptor, 1 8711 17p13.1 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0004713 (EC: IDA, PMID: 10873601); GO_0004715 (EC: NAS, PMID: 10873601); GO_0004871 (EC: TAS, PMID: 8632913); GO_0005515 (EC: IPI, PMID: 10873601); GO_0005524 (EC: IDA, PMID: 10873601); GO_0005737 (EC: IDA, PMID: 10873601); GO_0005829 (EC: IEA); GO_0006468 (EC: TAS, PMID: 8632913); GO_0007165 (EC: TAS, PMID: 8632913); GO_0016020 (EC: IDA, PMID: 10873601); GO_0018108 (EC: IDA, PMID: 10873601); GO_0018108 (EC: TAS, PMID: 8632913); GO_0030054 (EC: IDA); GO_0030308 (EC: IEA); GO_0046580 (EC: IEA); GO_0046777 (EC: IDA, PMID: 10873601) PMID: 8125298; 8632913; 10873601; 12477932; 15489334; 15778465; 16344560; 17471239; 18830724; 18976975; 20090780; 20413850; 20534741; 20574532; 21536687; 21890473; 21906983; 22939624; 24449862 tyrosine kinase, non-receptor, 1 TNK1 Bin Zhao, Yue Liu, Oliver He Hs.89862 WEB: http://www.ncbi.nlm.nih.gov/gene TRADD TNFRSF1A-associated via death domain 8717 16q22 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0004871 (EC: IEA); GO_0005164 (EC: IEA); GO_0005515 (EC: IPI, PMID: 1040062); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA, PMID: 11684708); GO_0005829 (EC: TAS); GO_0005856 (EC: IEA); GO_0006915 (EC: TAS); GO_0006919 (EC: TAS); GO_0007165 (EC: TAS, PMID: 7758105); GO_0008625 (EC: TAS, PMID: 8612133); GO_0019900 (EC: IPI, PMID: 8612133); GO_0031264 (EC: TAS, PMID: 18309324); GO_0032403 (EC: IEA); GO_0033209 (EC: TAS, PMID: 8612133); GO_0042802 (EC: IPI, PMID: 11684708); GO_0043065 (EC: TAS, PMID: 18309324); GO_0043123 (EC: IEP, PMID: 12761501); GO_0043235 (EC: IDA, PMID: 8612133); GO_0045121 (EC: IEA); GO_0051092 (EC: TAS, PMID: 18309324); GO_0051291 (EC: IEA); GO_0051798 (EC: IEA); GO_0060090 (EC: IPI, PMID: 8612133); GO_0070513 (EC: IPI, PMID: 8612133); GO_0097190 (EC: TAS); GO_0097191 (EC: IMP, PMID: 16611992); GO_0097191 (EC: TAS, PMID: 18309324); GO_2001239 (EC: TAS) PMID: 1040062; 7758105; 8565075; 8612133; 8621670; 8681376; 8702708; 8934525; 8943045; 9020361; 9082980; 9356494; 9427646; 9430227; 9560245; 9714541; 9915703; 9916731; 9916988; 10187805; 10356400; 10400625; 10544141; 10848577; 10892748; 10911999; 10980203; 11032752; 11035039; 11112409; 11112773; 11181075; 11226577; 11435712; 11479302; 11684708; 11821416; 11934887; 12045187; 12107169; 12417987; 12446787; 12477932; 12576460; 12604596; 12665801; 12753742; 12761501; 12796506; 12887920; 12911633; 14585990; 14644197; 14660619; 14702039; 14743216; 15103018; 15247912; 15310755; 15485837; 15489334; 15707590; 15761471; 16006552; 16227624; 16344560; 16603398; 16611992; 17051333; 17235653; 17540176; 17702576; 17922260; 18174230; 18198944; 18309324; 18661484; 18776134; 18939944; 18990758; 19151112; 19176810; 19287455; 19336370; 19379743; 19453261; 19573080; 19773279; 19781631; 19815541; 19854717; 20005846; 20568250; 20628368; 21068102; 21421854; 21724995; 21906983; 22099304; 22170762; 22179575; 22297296; 22510408; 22561347; 23732909; 23908590; 23955153; 23982205; 24130170; 24250222; 24374337 TNFRSF1A-associated via death domain HGNC:12030 HPRD:04610 MIM:603500 TRADD Bin Zhao, Yue Liu, Oliver He DP5 HARAKIRI WEB: http://www.ncbi.nlm.nih.gov/gene HRK harakiri, BCL2 interacting protein 8739 12q24.22 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 14596824); GO_0005739 (EC: IDA, PMID: 15031724); GO_0006915 (EC: IEA); GO_0016021 (EC: IEA); GO_0032464 (EC: IDA); GO_0043065 (EC: IMP, PMID: 15031724); GO_0090200 (EC: IDA) PMID: 9130713; 9228060; 10075695; 11076863; 11331593; 11483855; 11796190; 12217801; 12477932; 12606589; 14596824; 14695142; 15031724; 15694340; 15721256; 16697956; 18008329; 18037991; 19322201; 19641496; 20379614; 20855536; 21209886; 21666788; 21731739; 22005931; 22504417; 22504421; 22773666; 22964433; 23090478; 23192964; 23580416 harakiri, BCL2 interacting protein HGNC:5185 HPRD:04581 MIM:603447 HRK Bin Zhao, Yue Liu, Oliver He CARD3 CARDIAK CCK GIG30 RICK RIP2 WEB: http://www.ncbi.nlm.nih.gov/gene RIPK2 receptor-interacting serine-threonine kinase 2 8767 WUGSC:H_RG437L15.1 8q21 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0000187 (EC: TAS); GO_0001961 (EC: IEA); GO_0002224 (EC: TAS); GO_0002250 (EC: ISS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0002827 (EC: IEA); GO_0004674 (EC: IEA); GO_0004715 (EC: IEA); GO_0004871 (EC: TAS, PMID: 9642260); GO_0005515 (EC: IPI, PMID: 19337385); GO_0005524 (EC: IEA); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0005856 (EC: IDA); GO_0006915 (EC: IEA); GO_0006954 (EC: TAS, PMID: 9705938); GO_0007165 (EC: TAS, PMID: 9642260); GO_0007249 (EC: ISS); GO_0007254 (EC: TAS); GO_0010800 (EC: IDA); GO_0030274 (EC: IPI, PMID: 15657077); GO_0031398 (EC: IMP, PMID: 15620648); GO_0031398 (EC: NAS); GO_0031663 (EC: IEA); GO_0031982 (EC: IDA); GO_0032722 (EC: IEA); GO_0032727 (EC: NAS); GO_0032728 (EC: NAS); GO_0032729 (EC: IEA); GO_0032735 (EC: NAS); GO_0032743 (EC: IEA); GO_0032755 (EC: IEA); GO_0032760 (EC: IEA); GO_0033091 (EC: IEA); GO_0033138 (EC: IDA); GO_0034134 (EC: IDA, PMID: 11894098); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035666 (EC: TAS); GO_0035872 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042098 (EC: IEA); GO_0042803 (EC: IDA, PMID: 19337385); GO_0043065 (EC: IEA); GO_0043066 (EC: TAS); GO_0043123 (EC: IDA, PMID: 10329646); GO_0043234 (EC: IDA); GO_0043330 (EC: IEA); GO_0045087 (EC: IDA); GO_0045087 (EC: ISS); GO_0045087 (EC: TAS); GO_0045627 (EC: IEA); GO_0045944 (EC: NAS); GO_0046330 (EC: IEA); GO_0046641 (EC: IEA); GO_0048011 (EC: TAS); GO_0050700 (EC: IDA, PMID: 10329646); GO_0050700 (EC: IPI, PMID: 11087742); GO_0050731 (EC: IDA); GO_0050830 (EC: IEA); GO_0050852 (EC: ISS); GO_0050852 (EC: TAS); GO_0051092 (EC: IMP); GO_0051092 (EC: TAS); GO_0051403 (EC: TAS); GO_0070374 (EC: IEA); GO_0070423 (EC: TAS); GO_0070427 (EC: IEA); GO_0070431 (EC: IDA); GO_0070555 (EC: IEA); GO_0070671 (EC: IEA); GO_0070673 (EC: IEA); GO_0071223 (EC: IEA); GO_0071224 (EC: IEA); GO_0071225 (EC: IDA) PMID: 9575181; 9642260; 9705938; 10224040; 10329646; 10559258; 10719670; 10880512; 11087742; 11432859; 11487608; 11536016; 11894097; 11894098; 12138198; 12459189; 12477932; 12755636; 12761501; 12775719; 12938929; 12975309; 14638696; 15276183; 15489334; 15620648; 15657077; 15691841; 15761153; 16189514; 16344560; 16354923; 16418290; 16421571; 16492792; 16498402; 16517750; 16582588; 16824733; 16920334; 16997282; 17054981; 17075290; 17192257; 17348859; 17353931; 17355968; 17468049; 17851464; 17947236; 17965022; 18029348; 18079694; 18329614; 18342009; 18359207; 18426885; 18566542; 19121870; 19336552; 19337385; 19406482; 19464198; 19573080; 19592251; 19667203; 19693652; 19721713; 19773279; 19911254; 20018961; 20025869; 20125193; 20645315; 20800603; 20949042; 21048031; 21097508; 21123652; 21139048; 21757725; 21862576; 21887730; 21903422; 21906983; 21931591; 22075569; 22484241; 22504414; 22547678; 22607974; 22615316; 22665475; 22685397; 22815893; 22828789; 22993319; 23128233; 23300079; 23333941; 23437331; 23455924; 23818254; 23892723; 24015287; 24250222 receptor-interacting serine-threonine kinase 2 Ensembl:ENSG00000104312 HGNC:10020 HPRD:04585 MIM:603455 Vega:OTTHUMG00000163809 RIPK2 Bin Zhao, Yue Liu, Oliver He MORT1 WEB: http://www.ncbi.nlm.nih.gov/gene FADD Fas (TNFRSF6)-associated via death domain 8772 GIG3 11q13.3 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0001916 (EC: ISS); GO_0002020 (EC: IPI, PMID: 9208847); GO_0002224 (EC: TAS); GO_0002756 (EC: TAS); GO_0002821 (EC: ISS); GO_0005123 (EC: TAS, PMID: 7538907); GO_0005164 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10442631); GO_0005829 (EC: TAS); GO_0006915 (EC: IMP); GO_0006915 (EC: TAS); GO_0006919 (EC: TAS); GO_0008625 (EC: TAS, PMID: 7538907); GO_0016032 (EC: IEA); GO_0031264 (EC: IDA, PMID: 11101870); GO_0031264 (EC: TAS, PMID: 18309324); GO_0031265 (EC: IDA); GO_0032729 (EC: ISS); GO_0032757 (EC: IDA, PMID: 16127453); GO_0032760 (EC: IDA, PMID: 16127453); GO_0032813 (EC: IPI); GO_0033077 (EC: ISS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0035666 (EC: TAS); GO_0035877 (EC: IPI, PMID: 11717445); GO_0042104 (EC: ISS); GO_0042802 (EC: IPI, PMID: 7536190); GO_0043005 (EC: IEA); GO_0043029 (EC: ISS); GO_0043065 (EC: IMP); GO_0043123 (EC: IEP, PMID: 12761501); GO_0044297 (EC: IEA); GO_0045087 (EC: TAS); GO_0045121 (EC: IEA); GO_0045651 (EC: IMP, PMID: 17047155); GO_0045862 (EC: IDA, PMID: 18387192); GO_0045944 (EC: IDA, PMID: 16127453); GO_0048535 (EC: ISS); GO_0048536 (EC: ISS); GO_0048538 (EC: ISS); GO_0051291 (EC: IEA); GO_0051607 (EC: IMP); GO_0060340 (EC: IMP); GO_0070236 (EC: ISS); GO_0071260 (EC: IEP, PMID: 19593445); GO_0097049 (EC: IEA); GO_0097190 (EC: IDA, PMID: 11101870); GO_0097190 (EC: TAS); GO_0097191 (EC: IDA); GO_0097191 (EC: IMP, PMID: 16611992); GO_0097191 (EC: TAS, PMID: 18309324); GO_0097192 (EC: IEA); GO_0097202 (EC: IDA, PMID: 18387192); GO_0097342 (EC: IDA); GO_0097527 (EC: IMP, PMID: 11101870); GO_1902043 (EC: IEA); GO_2000454 (EC: ISS); GO_2001238 (EC: IMP); GO_2001239 (EC: TAS) PMID: 7536190; 7538907; 8565075; 8681376; 8906799; 8955195; 8967952; 9037025; 9045686; 9082980; 9208847; 9215629; 9228018; 9325248; 9326610; 9430227; 9521326; 9560245; 9582077; 9721089; 9774341; 9990010; 10235259; 10442631; 10493725; 10542291; 10640736; 10825539; 10848577; 10880445; 10894160; 10911999; 11002422; 11034606; 11035039; 11048727; 11101870; 11112409; 11353862; 11376335; 11395500; 11717445; 11739185; 11740202; 11741985; 11752160; 11753396; 11805265; 11828002; 11854271; 11859150; 11877464; 11940602; 11965497; 11975981; 12037669; 12107169; 12122017; 12196516; 12198154; 12220669; 12235128; 12477932; 12482751; 12496482; 12499380; 12604344; 12684039; 12702723; 12702765; 12721308; 12753742; 12761501; 12796506; 12815462; 12851487; 12887920; 12911633; 12954630; 14573612; 14644197; 14694156; 15034549; 15048887; 15069192; 15173180; 15207703; 15280356; 15383280; 15388581; 15452117; 15452120; 15485835; 15489334; 15601308; 15645452; 15659383; 15665818; 15688372; 15761471; 15778222; 15782135; 15849201; 15916534; 15956881; 16003390; 16006552; 16061179; 16109772; 16127453; 16169070; 16177127; 16227629; 16258269; 16289096; 16339514; 16360037; 16410793; 16450001; 16498403; 16528386; 16538383; 16611992; 16710361; 16762833; 16844082; 16871589; 16937440; 17031492; 17047155; 17159907; 17235653; 17290218; 17360386; 17511679; 17656375; 17911615; 17975136; 17977957; 18029348; 18174230; 18309324; 18328427; 18387192; 18485876; 18632871; 18632964; 18813792; 18840411; 19060883; 19074885; 19118384; 19125371; 19176810; 19303913; 19336038; 19362094; 19364499; 19373245; 19415536; 19453261; 19524513; 19557578; 19573080; 19583773; 19593445; 19773279; 19955841; 20040024; 20070122; 20353946; 20420860; 20438666; 20448643; 20484047; 20568250; 20588308; 20802294; 20890306; 20935634; 20943999; 20947025; 21048031; 21052097; 21109225; 21115735; 21183682; 21315423; 21382479; 21458669; 21525013; 21613217; 21620750; 21706480; 21724995; 21737329; 21785459; 21803845; 21822306; 21894190; 21900206; 21978935; 21979465; 21988832; 22126763; 22130896; 22179575; 22253026; 22266862; 22274400; 22297296; 22322857; 22585859; 22838074; 22848449; 22864571; 22922561; 23096115; 23142077; 23606538; 23760276; 23763459; 23972990; 24250222 Fas (TNFRSF6)-associated via death domain Ensembl:ENSG00000168040 HGNC:3573 HPRD:03909 MIM:602457 Vega:OTTHUMG00000167264 FADD Bin Zhao, Yue Liu, Oliver He CO9 PSPHL WEB: http://www.ncbi.nlm.nih.gov/gene PSPHP1 phosphoserine phosphatase pseudogene 1 8781 7q11.2 20140408 9606 7 pseudo Official from a nomenclature committee GO_0004647 (EC: TAS, PMID: 9573387); GO_0008283 (EC: TAS, PMID: 9573387); GO_0016311 (EC: TAS, PMID: 9573387) PMID: 9573387; 12477932 phosphoserine phosphatase pseudogene 1 HGNC:9578 MIM:604239 PSPHP1 Bin Zhao, Yue Liu, Oliver He CD263 DCR1 DCR1-TNFR LIT TRAIL-R3 TRAILR3 TRID WEB: http://www.ncbi.nlm.nih.gov/gene TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8794 UNQ321/PRO366 8p22-p21 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0004888 (EC: TAS, PMID: 9314565); GO_0005887 (EC: TAS, PMID: 9314565); GO_0006915 (EC: IEA); GO_0007165 (EC: TAS, PMID: 9314565); GO_0031225 (EC: IEA); GO_0045569 (EC: IEA) PMID: 9242610; 9242611; 9314565; 9325248; 9373179; 9551946; 9613612; 10435597; 11001921; 11024459; 11396170; 11417478; 11420819; 11442750; 11451151; 11464279; 11753607; 11844843; 11848467; 11859410; 12136286; 12390973; 12417331; 12477932; 12488957; 12808117; 12975309; 14623878; 14999791; 15207703; 15301860; 15340161; 15489334; 15538968; 15916713; 15921376; 15990565; 16046522; 16169070; 16174727; 16980609; 17522430; 17690453; 18345033; 18460741; 18511705; 18590575; 19035483; 19573080; 19661294; 19773279; 19936781; 20237496; 20451496; 20568250; 20799941; 21281967; 21483669; 22555108; 23320456; 23602568; 24211571 tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain Ensembl:ENSG00000173535 HGNC:11906 HPRD:04681 MIM:603613 Vega:OTTHUMG00000097844 TNFRSF10C Bin Zhao, Yue Liu, Oliver He GAL2-R GALNR2 GALR-2 WEB: http://www.ncbi.nlm.nih.gov/gene GALR2 galanin receptor 2 8811 17q25.3 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0004966 (EC: IEA); GO_0005515 (EC: IPI); GO_0005886 (EC: TAS); GO_0006936 (EC: TAS, PMID: 9480833); GO_0007166 (EC: TAS, PMID: 9480833); GO_0007188 (EC: TAS, PMID: 9685625); GO_0007194 (EC: IEA); GO_0007204 (EC: IEA); GO_0007218 (EC: TAS, PMID: 9480833); GO_0007268 (EC: TAS, PMID: 9832121); GO_0007275 (EC: TAS, PMID: 9480833); GO_0007586 (EC: TAS, PMID: 9832121); GO_0007611 (EC: TAS, PMID: 9480833); GO_0007631 (EC: TAS, PMID: 9480833); GO_0016021 (EC: IEA); GO_0031175 (EC: IEA) PMID: 2834384; 9480833; 9685625; 9832121; 9880084; 11867941; 12477932; 14592962; 15489334; 17083333; 18272487; 18577758; 19086053; 21345369; 21850381; 21894515; 22329353; 22889491; 23237663; 23278944; 23341594; 24122450 galanin receptor 2 Ensembl:ENSG00000182687 HGNC:4133 HPRD:04735 MIM:603691 Vega:OTTHUMG00000167479 GALR2 Bin Zhao, Yue Liu, Oliver He ANF CPHD5 RPX WEB: http://www.ncbi.nlm.nih.gov/gene HESX1 HESX homeobox 1 8820 3p14.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0003677 (EC: TAS, PMID: 9620767); GO_0003682 (EC: IEA); GO_0003700 (EC: IEA); GO_0005515 (EC: IPI); GO_0005634 (EC: IEA); GO_0006351 (EC: IEA); GO_0007420 (EC: TAS, PMID: 9620767); GO_0008022 (EC: IEA); GO_0030916 (EC: IEA); GO_0043565 (EC: IEA); GO_0043584 (EC: IEA); GO_0045892 (EC: IEA); GO_0047485 (EC: IEA); GO_0048853 (EC: IEA) PMID: 7876132; 8696006; 9373136; 9620767; 9751061; 11136712; 11283314; 11731482; 11748154; 12063185; 12424431; 12477932; 12519827; 14557462; 14561704; 14646405; 14714741; 15489334; 16424673; 16940453; 17148560; 17587179; 17931718; 18728160; 19561080; 20181723; 20211142; 20534763; 20694410; 20949537; 21270112; 21325470; 21761366; 23199197; 23455924; 23465708 HESX homeobox 1 HGNC:4877 HPRD:03482 MIM:601802 HESX1 Bin Zhao, Yue Liu, Oliver He CCN4 WISP1c WISP1i WISP1tc WEB: http://www.ncbi.nlm.nih.gov/gene WISP1 WNT1 inducible signaling pathway protein 1 8840 8q24.22 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0001558 (EC: IEA); GO_0005520 (EC: IEA); GO_0005615 (EC: NAS, PMID: 9843955); GO_0005737 (EC: IDA); GO_0007155 (EC: IEA); GO_0007165 (EC: TAS, PMID: 9843955); GO_0007267 (EC: TAS, PMID: 9843955); GO_0016055 (EC: IEA) PMID: 9843955; 10716946; 11571650; 11598131; 11751417; 11782444; 11855747; 12477932; 12529380; 12717393; 12805222; 15489334; 15650268; 16421571; 17353931; 17381509; 17406949; 17579708; 17593496; 17657846; 18006828; 18029348; 18404666; 18701807; 19069651; 19180479; 19238344; 19240061; 19282865; 19287097; 19339243; 19453261; 19926868; 20010302; 20074638; 20372786; 20379614; 20403915; 20506641; 20628624; 20677014; 20684029; 21109017; 21321938; 21453685; 21498727; 21516124; 22778029; 22873724; 23300278; 23313051; 23316072; 23612905 WNT1 inducible signaling pathway protein 1 HGNC:12769 HPRD:16019 MIM:603398 WISP1 Bin Zhao, Yue Liu, Oliver He CDK5P35 CDK5R NCK5A p23 p25 p35 p35nck5a WEB: http://www.ncbi.nlm.nih.gov/gene CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 8851 17q11.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000079 (EC: TAS, PMID: 7592934); GO_0001764 (EC: ISS); GO_0004672 (EC: TAS, PMID: 7592934); GO_0004693 (EC: IEA); GO_0005509 (EC: ISS); GO_0005515 (EC: IPI, PMID: 10721722); GO_0005634 (EC: ISS); GO_0005737 (EC: ISS); GO_0005829 (EC: TAS); GO_0005886 (EC: IEA); GO_0007158 (EC: ISS); GO_0007213 (EC: ISS); GO_0007411 (EC: ISS); GO_0007411 (EC: TAS); GO_0007413 (EC: ISS); GO_0007420 (EC: ISS); GO_0007420 (EC: NAS, PMID: 10915792); GO_0008283 (EC: TAS, PMID: 8090221); GO_0009790 (EC: ISS); GO_0014069 (EC: ISS); GO_0016020 (EC: ISS); GO_0016301 (EC: ISS); GO_0016533 (EC: IEA); GO_0016534 (EC: IEA); GO_0018105 (EC: IDA, PMID: 12832520); GO_0018107 (EC: IDA, PMID: 12832520); GO_0019901 (EC: IPI, PMID: 12832520); GO_0021549 (EC: IEA); GO_0021722 (EC: IEA); GO_0021766 (EC: IEA); GO_0021819 (EC: IEA); GO_0030182 (EC: ISS); GO_0030424 (EC: ISS); GO_0030425 (EC: ISS); GO_0030426 (EC: ISS); GO_0030517 (EC: IEA); GO_0031175 (EC: ISS); GO_0031594 (EC: ISS); GO_0032956 (EC: IEA); GO_0033136 (EC: IEA); GO_0035235 (EC: ISS); GO_0043025 (EC: ISS); GO_0043197 (EC: ISS); GO_0043292 (EC: ISS); GO_0043525 (EC: ISS); GO_0043539 (EC: IDA, PMID: 12832520); GO_0043539 (EC: ISS); GO_0045296 (EC: ISS); GO_0045664 (EC: NAS, PMID: 10721722); GO_0045892 (EC: IMP); GO_0046875 (EC: IEA); GO_0048013 (EC: ISS); GO_0048471 (EC: IDA, PMID: 12832520); GO_0061001 (EC: ISS); GO_0070507 (EC: IEA); GO_0090314 (EC: IEA) PMID: 7556643; 7592934; 8090221; 9010203; 9038181; 9933594; 10604467; 10721722; 10753743; 10830966; 10915792; 11113134; 11168528; 11389014; 11583627; 11604394; 11741927; 11784720; 11882646; 12037672; 12084709; 12223541; 12226093; 12230554; 12477932; 12491158; 12688339; 12826674; 12832492; 12832520; 12859671; 14521924; 14702039; 14976144; 15013773; 15123618; 15175076; 15342635; 15489224; 15489334; 15492003; 15536496; 15689152; 15741232; 15917097; 16189514; 16407256; 16425041; 16678793; 17036052; 17060323; 17121855; 17207965; 17491008; 17493033; 17496813; 17591690; 17762160; 18053171; 18247371; 18325333; 18829967; 19081376; 19154537; 19638632; 19874574; 19913121; 19953087; 20097924; 20354813; 20518484; 20618441; 20628086; 21130530; 21220307; 21544067; 21625387; 21772061; 21832049; 22654103; 22964075; 23151508; 23455922; 23602568; 24085300 cyclin-dependent kinase 5, regulatory subunit 1 (p35) Ensembl:ENSG00000176749 HGNC:1775 HPRD:04586 MIM:603460 Vega:OTTHUMG00000132814 CDK5R1 Bin Zhao, Yue Liu, Oliver He SPHK WEB: http://www.ncbi.nlm.nih.gov/gene SPHK1 sphingosine kinase 1 8877 17q25.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000287 (EC: IDA, PMID: 10947957); GO_0000287 (EC: ISS); GO_0001568 (EC: IEA); GO_0001934 (EC: IEA); GO_0001956 (EC: IEA); GO_0003677 (EC: IDA, PMID: 12393916); GO_0003951 (EC: IEA); GO_0004143 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12080051); GO_0005516 (EC: IDA, PMID: 10947957); GO_0005524 (EC: IDA, PMID: 12393916); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS, PMID: 10863092); GO_0005886 (EC: IDA); GO_0006457 (EC: TAS); GO_0006665 (EC: TAS); GO_0006670 (EC: IDA); GO_0006954 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10751414); GO_0007205 (EC: IEA); GO_0007420 (EC: IEA); GO_0007565 (EC: IEA); GO_0008021 (EC: IEA); GO_0008481 (EC: IDA, PMID: 12393916); GO_0009267 (EC: IEA); GO_0010803 (EC: IDA); GO_0010976 (EC: IEA); GO_0014075 (EC: IEA); GO_0017050 (EC: IDA, PMID: 10863092); GO_0019371 (EC: IEA); GO_0019722 (EC: IDA, PMID: 10947957); GO_0030148 (EC: TAS); GO_0030307 (EC: IDA, PMID: 12441135); GO_0030335 (EC: IDA, PMID: 12441135); GO_0030424 (EC: IEA); GO_0031398 (EC: IDA); GO_0032026 (EC: IEA); GO_0032570 (EC: IEA); GO_0032651 (EC: IEA); GO_0033198 (EC: IEA); GO_0035556 (EC: TAS, PMID: 10947957); GO_0042346 (EC: IMP); GO_0043066 (EC: IDA, PMID: 15623571); GO_0043066 (EC: TAS, PMID: 10947957); GO_0044267 (EC: TAS); GO_0044281 (EC: TAS); GO_0045766 (EC: IDA, PMID: 12441135); GO_0045931 (EC: IDA, PMID: 12441135); GO_0045987 (EC: IDA, PMID: 12847068); GO_0046521 (EC: NAS, PMID: 10863092); GO_0046834 (EC: IDA, PMID: 12393916); GO_0048146 (EC: IDA, PMID: 15623571); GO_0051084 (EC: TAS); GO_0051092 (EC: IMP); GO_0051721 (EC: IPI); GO_0070301 (EC: IEA); GO_0070555 (EC: IEA); GO_0071363 (EC: IEA) PMID: 7698749; 8125298; 8889549; 9726979; 10751414; 10802064; 10863092; 10947957; 11777919; 11915350; 12077123; 12080051; 12124383; 12393916; 12441135; 12444147; 12477932; 12847068; 14532121; 14575709; 14702039; 14742298; 14988393; 15052627; 15191888; 15193146; 15265705; 15302883; 15342556; 15585953; 15623571; 15632208; 15693752; 15710602; 15749892; 15855330; 16038795; 16194537; 16243846; 16316995; 16507765; 16516161; 16529909; 16571380; 16623665; 16888242; 17064696; 17114809; 17124500; 17388800; 17482291; 17519232; 17599053; 17641298; 17822721; 18058224; 18178871; 18192241; 18199826; 18261991; 18263879; 18362204; 18401414; 18426913; 18644866; 18718048; 18775504; 18824518; 18849324; 18852266; 18922940; 18980995; 19017993; 19074142; 19116345; 19162217; 19238330; 19240026; 19633297; 19657322; 19706837; 19782042; 19815712; 19830907; 19854831; 19914200; 19956567; 20053797; 20104488; 20237496; 20386061; 20404323; 20519401; 20520628; 20606403; 20634980; 20661259; 20838377; 20846391; 20889557; 20926375; 21075134; 21075214; 21139048; 21209394; 21304987; 21392092; 21418911; 21464128; 21575515; 21625639; 21672077; 21696364; 21756066; 21769916; 21936950; 21940753; 21988832; 22016563; 22155656; 22227192; 22315056; 22322056; 22322303; 22331716; 22422617; 22450659; 22460268; 22684547; 22733311; 22781898; 22833671; 22961081; 23166225; 23232649; 23314175; 23359503; 23426175; 23462226; 23466305; 23576579; 23602659; 23651497; 23658376; 23839903; 23861887; 23928990; 23939980; 23955546 sphingosine kinase 1 Ensembl:ENSG00000176170 HGNC:11240 HPRD:04768 MIM:603730 Vega:OTTHUMG00000180177 SPHK1 Bin Zhao, Yue Liu, Oliver He BETA-TRCP FBW1A FBXW1 FBXW1A FWD1 bTrCP bTrCP1 betaTrCP WEB: http://www.ncbi.nlm.nih.gov/gene BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 8945 RP11-529I10.2 10q24.32 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0000086 (EC: TAS); GO_0000209 (EC: IEA); GO_0000278 (EC: TAS); GO_0004842 (EC: IDA, Qualifier: contributes_to, PMID: 15448698); GO_0005515 (EC: IPI, PMID: 11238952); GO_0005634 (EC: IEA); GO_0005829 (EC: TAS); GO_0006470 (EC: IEA); GO_0006511 (EC: IDA, PMID: 15448698); GO_0007165 (EC: TAS, PMID: 9990853); GO_0008013 (EC: IEA); GO_0016032 (EC: TAS); GO_0016055 (EC: IEA); GO_0016567 (EC: IDA, PMID: 16885022); GO_0019005 (EC: IDA, PMID: 19966869); GO_0031145 (EC: TAS); GO_0031146 (EC: IBA); GO_0031648 (EC: IMP, PMID: 16885022); GO_0033598 (EC: IEA); GO_0042753 (EC: IEA); GO_0043122 (EC: IEA); GO_0043433 (EC: TAS, PMID: 11001584); GO_0045309 (EC: IEA); GO_0045862 (EC: IMP, PMID: 16885022); GO_0045879 (EC: TAS, PMID: 11001584); GO_0045892 (EC: IMP, PMID: 19966869); GO_0045893 (EC: IEA); GO_0046983 (EC: IEA); GO_0051437 (EC: TAS); GO_0051439 (EC: TAS); GO_0051726 (EC: IEA); GO_0060444 (EC: IEA); GO_0061136 (EC: IEA); GO_0071407 (EC: IEA) PMID: 8889548; 9660940; 9859996; 9990852; 9990853; 10023660; 10066435; 10072378; 10074433; 10075690; 10228155; 10331953; 10514424; 10514433; 10531035; 10564661; 10644755; 10713156; 10803460; 10828603; 10835356; 10918611; 10983987; 11001584; 11027288; 11158290; 11238952; 11278695; 11359933; 11483504; 11696595; 11818547; 11850407; 11953428; 11994270; 12037680; 12077367; 12114015; 12124804; 12151397; 12417018; 12477932; 12482991; 12504025; 12609982; 12684064; 12791267; 12820959; 12902344; 14516475; 14526201; 14561767; 14603323; 14673179; 14674748; 14676825; 14681206; 14706645; 14743216; 14752276; 14988407; 15070733; 15140882; 15314162; 15340078; 15448698; 15469984; 15485837; 15489334; 15647282; 15735746; 15743413; 15782160; 15798217; 15845771; 15855639; 15917222; 15927956; 15966899; 16165251; 16189514; 16196087; 16219772; 16275325; 16278670; 16303288; 16338364; 16344560; 16354571; 16371461; 16385451; 16651270; 16691619; 16705181; 16757476; 16778892; 16798748; 16865698; 16885021; 16885022; 17053147; 17079684; 17121803; 17213322; 17215248; 17217622; 17283138; 17295679; 17318178; 17319651; 17327410; 17387146; 17445772; 17463251; 17491012; 17500058; 17510365; 17586316; 17676996; 17937819; 17939994; 17965458; 18052253; 18056411; 18296647; 18316598; 18354482; 18354483; 18363964; 18372914; 18378770; 18460583; 18521620; 18541215; 18575781; 18617892; 18650423; 18662541; 18672082; 18765672; 18794143; 18851830; 19053519; 19061640; 19106159; 19150432; 19159283; 19196987; 19240029; 19240121; 19244337; 19297328; 19372209; 19411070; 19477924; 19478868; 19515779; 19557001; 19615732; 19647520; 19656241; 19730691; 19797085; 19822658; 19931512; 19933270; 19944437; 19955572; 19966869; 20048001; 20068069; 20102634; 20140206; 20201792; 20348946; 20353940; 20378537; 20379614; 20442859; 20503246; 20516151; 20531388; 20558726; 20625400; 20638939; 20708156; 20736409; 20797629; 20844743; 20852628; 20858893; 20980512; 21051950; 21070969; 21138764; 21139048; 21145461; 21173164; 21189257; 21249194; 21310048; 21402774; 21430439; 21454620; 21466614; 21521785; 21572392; 21807946; 21900206; 21910689; 21946088; 21987572; 21988832; 22017875; 22017876; 22017877; 22022389; 22034227; 22045853; 22078877; 22087322; 22090097; 22190034; 22350919; 22388891; 22454292; 22514278; 22586265; 22590978; 22669845; 22682247; 22692215; 22711876; 22730322; 22751928; 22851693; 22912335; 22939624; 22964642; 22975506; 23027877; 23056346; 23071779; 23115237; 23297342; 23440515; 23453757; 23455922; 23530064; 23532963; 23563313; 23583392; 23607312; 23640883; 23737552; 23769673; 23861398; 23912711; 23972993; 24211209; 24211253; 24248593; 24250222; 24318128; 24429874; 24469040; 24501426 beta-transducin repeat containing E3 ubiquitin protein ligase Ensembl:ENSG00000166167 HGNC:1144 HPRD:04596 MIM:603482 Vega:OTTHUMG00000018932 BTRC Bin Zhao, Yue Liu, Oliver He C25H WEB: http://www.ncbi.nlm.nih.gov/gene CH25H cholesterol 25-hydroxylase 9023 10q23 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0001567 (EC: IEA); GO_0005506 (EC: IEA); GO_0005789 (EC: IEA); GO_0005829 (EC: TAS); GO_0006629 (EC: TAS, PMID: 9852097); GO_0006633 (EC: IEA); GO_0006699 (EC: TAS); GO_0008203 (EC: IEA); GO_0008206 (EC: TAS); GO_0008395 (EC: TAS); GO_0016021 (EC: IEA); GO_0016126 (EC: IEA); GO_0044281 (EC: TAS) PMID: 9852097; 12477932; 15164054; 15465627; 15489334; 16157450; 16385451; 16909003; 17373700; 18830724; 20413850; 20445134; 20534741; 20535486; 20574532; 20699362; 21041692 cholesterol 25-hydroxylase Ensembl:ENSG00000138135 HGNC:1907 HPRD:05183 MIM:604551 Vega:OTTHUMG00000018705 CH25H Bin Zhao, Yue Liu, Oliver He NAE2 UBE1C hUBA3 WEB: http://www.ncbi.nlm.nih.gov/gene UBA3 ubiquitin-like modifier activating enzyme 3 9039 3p14.1 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 10722740); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0006464 (EC: TAS, PMID: 9694792); GO_0006508 (EC: TAS, PMID: 9694792); GO_0007113 (EC: IEA); GO_0008641 (EC: IEA); GO_0016881 (EC: IEA); GO_0045116 (EC: IEA); GO_0046982 (EC: IPI, PMID: 12740388); GO_0051726 (EC: IEA) PMID: 9694792; 10207026; 10409428; 10722740; 11076863; 11230166; 11256614; 12477932; 12646924; 12740388; 14690597; 14702039; 15361859; 15489334; 15489336; 15694336; 16169070; 16381901; 16400609; 16503656; 16620772; 17220875; 17353931; 18264111; 18652489; 19250909; 19549727; 19615732; 21139048; 21145461; 21890473; 21906983; 21963094; 22404213; 22505724; 22821745; 22863883; 22939629; 23000965; 23455924 ubiquitin-like modifier activating enzyme 3 Ensembl:ENSG00000144744 HGNC:12470 HPRD:04413 MIM:603172 Vega:OTTHUMG00000154325 UBA3 Bin Zhao, Yue Liu, Oliver He UBC-RS2 UBC12 hUbc12 WEB: http://www.ncbi.nlm.nih.gov/gene UBE2M ubiquitin-conjugating enzyme E2M 9040 19q13.43 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0004842 (EC: IMP, PMID: 15694336); GO_0004842 (EC: TAS, PMID: 9694792); GO_0005515 (EC: IPI, PMID: 15361859); GO_0005524 (EC: IEA); GO_0005575 (EC: ND); GO_0005829 (EC: TAS); GO_0006464 (EC: IMP, PMID: 15694336); GO_0006464 (EC: TAS, PMID: 9694792); GO_0007179 (EC: TAS); GO_0016567 (EC: IMP, PMID: 15694336); GO_0016567 (EC: TAS, PMID: 9694792); GO_0018169 (EC: IDA, PMID: 15361859); GO_0019788 (EC: IDA, PMID: 19250909); GO_0043525 (EC: IEA); GO_0045116 (EC: IDA, PMID: 19250909); GO_0045116 (EC: IEA) PMID: 9694792; 10207026; 10722740; 10828074; 11574546; 12477932; 12522145; 12565873; 15242646; 15361859; 15489334; 15694336; 16275327; 16341674; 16503656; 16620772; 16735510; 17220875; 17353931; 17643375; 18096514; 18274552; 18652489; 18826954; 19245792; 19250909; 19549727; 19738201; 19953087; 20353940; 21139048; 21145461; 21247897; 21477582; 21765416; 21832049; 21853274; 21890473; 21906983; 21940857; 21946088; 21963094; 21987584; 22388932; 22412018; 22505724; 22623428; 22797925; 22939629; 23000965; 23201271; 23267066; 23383273; 23936405; 24192928; 24250222 ubiquitin-conjugating enzyme E2M Ensembl:ENSG00000130725 HGNC:12491 HPRD:04414 MIM:603173 Vega:OTTHUMG00000183548 UBE2M Bin Zhao, Yue Liu, Oliver He APG12 APG12L FBR93 HAPG12 WEB: http://www.ncbi.nlm.nih.gov/gene ATG12 autophagy related 12 9140 5q21-q22 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0000045 (EC: ISS); GO_0005515 (EC: IPI, PMID: 11096062); GO_0032480 (EC: TAS); GO_0034045 (EC: ISS); GO_0043234 (EC: IEA); GO_0045087 (EC: TAS) PMID: 8889548; 9490301; 9852036; 11096062; 11825910; 11890701; 12207896; 12477932; 12482611; 12665549; 14702039; 15146197; 15342556; 15489334; 16189514; 16344560; 17353931; 17457038; 18187620; 19124466; 19197948; 19901552; 20417604; 20562859; 20723759; 21139048; 21832049; 21906983; 22152474; 22170153; 22342342; 23202584; 23307622 autophagy related 12 Ensembl:ENSG00000145782 HGNC:588 HPRD:08496 MIM:609608 Vega:OTTHUMG00000128889 ATG12 Bin Zhao, Yue Liu, Oliver He ABRI BRI BRI2 BRICD2B E25B E3-16 FBD imBRI2 WEB: http://www.ncbi.nlm.nih.gov/gene ITM2B integral membrane protein 2B 9445 RP11-196P14.1 13q14.3 20140408 9606 13 protein-coding Official from a nomenclature committee GO_0001540 (EC: IPI, PMID: 19849849); GO_0005515 (EC: IPI, PMID: 16027166); GO_0005524 (EC: IEA); GO_0005576 (EC: TAS); GO_0005615 (EC: IDA, PMID: 18524908); GO_0005794 (EC: IDA); GO_0005886 (EC: IDA, PMID: 19114711); GO_0007399 (EC: TAS, PMID: 10391242); GO_0010008 (EC: IEA); GO_0030660 (EC: IDA, PMID: 17965014); GO_0031301 (EC: IDA, PMID: 10526337); GO_0042985 (EC: IDA, PMID: 16027166); GO_0043231 (EC: IDA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0097192 (EC: IEA) PMID: 5466275; 9795190; 10391242; 10526337; 10781099; 10931946; 12082633; 12196136; 12477932; 12903036; 14586629; 14656991; 15489334; 15968464; 15983050; 16027166; 16344560; 16612984; 17965014; 18029348; 18282158; 18440095; 18524908; 19056867; 19072909; 19114711; 19366692; 19748705; 19849849; 20036644; 20600910; 20972266; 21048150; 21139048; 21587206; 21752865; 21841249; 21873424; 21875946; 21890473; 21906983; 21963094; 22053931; 22190034; 22194595; 22505724; 23000965; 23261769; 23418567; 23701002; 24099305 integral membrane protein 2B Ensembl:ENSG00000136156 HGNC:6174 HPRD:04878 MIM:603904 Vega:OTTHUMG00000016894 ITM2B Bin Zhao, Yue Liu, Oliver He GSTO 1-1 GSTTLp28 HEL-S-21 P28 SPG-R WEB: http://www.ncbi.nlm.nih.gov/gene GSTO1 glutathione S-transferase omega 1 9446 RP11-99N20.1 10q25.1 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0004364 (EC: IDA, PMID: 11511179); GO_0005737 (EC: IDA, PMID: 11511179); GO_0005829 (EC: TAS); GO_0006805 (EC: TAS); GO_0010880 (EC: IDA, PMID: 11035031); GO_0010881 (EC: IC, PMID: 11035031); GO_0014810 (EC: IC, PMID: 11035031); GO_0016491 (EC: IDA, PMID: 11511179); GO_0019852 (EC: IDA, PMID: 11511179); GO_0042178 (EC: IDA, PMID: 12928150); GO_0044281 (EC: TAS); GO_0045174 (EC: IDA, PMID: 11511179); GO_0050610 (EC: IEA); GO_0060315 (EC: IDA, PMID: 11035031); GO_0060316 (EC: IDA, PMID: 11035031); GO_0070062 (EC: IDA, PMID: 19056867); GO_0071243 (EC: IDA, PMID: 11511179); GO_1901687 (EC: TAS) PMID: 8076819; 8889548; 9786866; 9988762; 10783391; 11035031; 11271497; 11457926; 11511179; 12477932; 12565892; 12618591; 12928150; 14570706; 15040808; 15146197; 15159516; 15164054; 15489334; 15623683; 15901998; 15917099; 15992993; 16169070; 16385451; 17158763; 17194543; 17213182; 17450230; 17484623; 17548696; 17601350; 17617905; 17637926; 17717316; 18065725; 18186040; 18216717; 18400112; 18414193; 18414634; 18427999; 18449862; 18571971; 18720901; 18799873; 18941778; 18977241; 18986335; 19056867; 19148497; 19152805; 19513904; 19624857; 19635583; 19686770; 19738201; 19859803; 19913121; 19914269; 20106899; 20113212; 20200426; 20210239; 20237496; 20367187; 20374258; 20472488; 20532380; 20547570; 20562859; 20628086; 20670920; 20800603; 20818931; 21094982; 21106529; 21139048; 21351650; 21832049; 21890473; 21906983; 21963094; 22100662; 22283150; 22293942; 22339537; 22440634; 22494505; 22505724; 22522127; 22747749; 22939629; 23000965; 23086268; 23824909; 23888047 glutathione S-transferase omega 1 Ensembl:ENSG00000148834 HGNC:13312 HPRD:10401 MIM:605482 Vega:OTTHUMG00000019001 GSTO1 Bin Zhao, Yue Liu, Oliver He PEK PERK WRS WEB: http://www.ncbi.nlm.nih.gov/gene EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 9451 2p12 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0001501 (EC: ISS); GO_0001503 (EC: IMP, PMID: 12086964); GO_0002063 (EC: ISS); GO_0004672 (EC: TAS, PMID: 10026192); GO_0004674 (EC: ISS); GO_0004674 (EC: TAS); GO_0004694 (EC: IDA, PMID: 10026192); GO_0004694 (EC: IMP, PMID: 12086964); GO_0005515 (EC: IPI, PMID: 11907036); GO_0005524 (EC: IEA); GO_0005737 (EC: ISS); GO_0005783 (EC: IC, PMID: 11907036); GO_0005783 (EC: ISS); GO_0005783 (EC: TAS, PMID: 12086964); GO_0005789 (EC: ISS); GO_0005789 (EC: NAS, PMID: 11907036); GO_0005789 (EC: TAS); GO_0006412 (EC: IEA); GO_0006468 (EC: ISS); GO_0006919 (EC: ISS); GO_0006983 (EC: IDA, PMID: 10677345); GO_0006987 (EC: TAS); GO_0007029 (EC: ISS); GO_0007595 (EC: IEA); GO_0009967 (EC: IEA); GO_0016021 (EC: IEA); GO_0017148 (EC: TAS, PMID: 12086964); GO_0019217 (EC: IEA); GO_0019722 (EC: ISS); GO_0019899 (EC: IPI); GO_0019903 (EC: IPI); GO_0030073 (EC: ISS); GO_0030282 (EC: ISS); GO_0030968 (EC: IDA, PMID: 10677345); GO_0030968 (EC: TAS, PMID: 19816510); GO_0031018 (EC: IMP, PMID: 12086964); GO_0031642 (EC: ISS); GO_0032057 (EC: TAS, PMID: 10677345); GO_0032092 (EC: IEA); GO_0032933 (EC: IEA); GO_0034976 (EC: IMP, PMID: 19061639); GO_0042802 (EC: IPI, PMID: 11907036); GO_0044267 (EC: TAS); GO_0045444 (EC: IEA); GO_0046777 (EC: IDA, PMID: 10026192); GO_0046777 (EC: IMP, PMID: 12086964); GO_0048009 (EC: ISS); GO_0051260 (EC: IMP, PMID: 11907036); GO_0070059 (EC: IEA) PMID: 1677563; 8099443; 9819435; 10026192; 10542257; 10575235; 10677345; 10848580; 10932183; 11555640; 11907036; 12014989; 12086964; 12370288; 12446770; 12446838; 12477932; 12610133; 14517290; 15146197; 15220213; 15234121; 15483661; 15489334; 15650164; 16147992; 16148948; 16288713; 16344560; 16720581; 17229688; 17785458; 17823375; 18063576; 18216498; 18426796; 18451152; 18664456; 18787411; 19009018; 19029953; 19061639; 19586904; 19816510; 19837917; 19913121; 20072656; 20103619; 20202148; 20348950; 20371724; 20379614; 20457808; 20463975; 20628086; 20709135; 20800603; 20881960; 21385877; 21419175; 21464971; 21518408; 21648287; 21685912; 21709020; 22028037; 22072062; 22169477; 22246806; 22253692; 22354021; 22446326; 22795130; 22813743; 22915762; 22917505; 22956602; 23103912; 23110043; 23116876; 23160380; 23471998; 23585173; 23592989; 23759358; 24103755; 24114838; 24457600 eukaryotic translation initiation factor 2-alpha kinase 3 Ensembl:ENSG00000172071 HGNC:3255 HPRD:04942 MIM:604032 Vega:OTTHUMG00000155046 EIF2AK3 Bin Zhao, Yue Liu, Oliver He GGPPS GGPPS1 WEB: http://www.ncbi.nlm.nih.gov/gene GGPS1 geranylgeranyl diphosphate synthase 1 9453 1q43 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0004161 (EC: IEA); GO_0004311 (EC: IDA, PMID: 10026212); GO_0004337 (EC: IEA); GO_0005829 (EC: TAS); GO_0006695 (EC: TAS); GO_0006720 (EC: IDA, PMID: 10026212); GO_0033384 (EC: IEA); GO_0033386 (EC: IEA); GO_0044281 (EC: TAS); GO_0045337 (EC: IEA); GO_0046872 (EC: IEA) PMID: 8419360; 9741684; 10026212; 10101267; 10931946; 12446740; 12477932; 15489334; 16698791; 16710414; 16806233; 17207965; 17536018; 17646172; 18726356; 20191015; 21139048; 21224049; 21321112; 21890473; 21906983; 22505724; 23478574 geranylgeranyl diphosphate synthase 1 Ensembl:ENSG00000152904 HGNC:4249 HPRD:06099 MIM:606982 Vega:OTTHUMG00000037963 GGPS1 Bin Zhao, Yue Liu, Oliver He APG5 APG5-LIKE APG5L ASP hAPG5 WEB: http://www.ncbi.nlm.nih.gov/gene ATG5 autophagy related 5 9474 6q21 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0000045 (EC: ISS); GO_0001974 (EC: IEA); GO_0002739 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11096062); GO_0005737 (EC: ISS); GO_0005776 (EC: IDA, PMID: 15292400); GO_0005930 (EC: ISS); GO_0006914 (EC: ISS); GO_0006915 (EC: IEA); GO_0009620 (EC: IEA); GO_0031397 (EC: IEA); GO_0032480 (EC: TAS); GO_0034045 (EC: ISS); GO_0042311 (EC: IEA); GO_0042493 (EC: IEA); GO_0043066 (EC: IEA); GO_0043687 (EC: ISS); GO_0045087 (EC: TAS); GO_0048840 (EC: IEA); GO_0055015 (EC: IEA); GO_0060047 (EC: IEA); GO_1902017 (EC: ISS) PMID: 7796880; 9563500; 9852036; 10702672; 11096062; 11266458; 11349150; 11725643; 11825910; 12207896; 12417306; 12477932; 12482611; 12665549; 12703993; 14574404; 14702039; 15292400; 15342556; 15489334; 15778222; 16341674; 17207965; 17353931; 18296641; 18353420; 18448665; 19066443; 19124466; 19148225; 19194464; 19197948; 19322201; 19375507; 19783847; 19838193; 19881538; 19901552; 20038797; 20190558; 20379614; 20417604; 20529838; 20562859; 20580051; 20639872; 20697744; 20962850; 21068098; 21139048; 21622776; 21655094; 21664058; 21722286; 21795849; 21906983; 21976705; 21995634; 22040493; 22052905; 22170153; 22342342; 22536318; 22863883; 22993366; 23075929; 23202584; 23235332; 23242420; 23273568; 23317196; 23322078; 23384565; 23429496; 23486359; 23740937; 24250222; 24269628; 24324106 autophagy related 5 Ensembl:ENSG00000057663 HGNC:589 HPRD:16051 MIM:604261 Vega:OTTHUMG00000016193 ATG5 Bin Zhao, Yue Liu, Oliver He IB1 JIP-1 JIP1 PRKM8IP WEB: http://www.ncbi.nlm.nih.gov/gene MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 9479 11p11.2 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0004860 (EC: TAS, PMID: 9933567); GO_0005078 (EC: IPI, PMID: 11238452); GO_0005515 (EC: IPI, PMID: 11517249); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA, PMID: 10574993); GO_0005789 (EC: IEA); GO_0005829 (EC: IEA); GO_0006355 (EC: IEA); GO_0007258 (EC: IEA); GO_0008432 (EC: IEA); GO_0009967 (EC: IPI, PMID: 11238452); GO_0016192 (EC: ISS); GO_0019894 (EC: IPI, PMID: 11238452); GO_0019901 (EC: IPI, PMID: 11238452); GO_0031434 (EC: IEA); GO_0031435 (EC: IEA); GO_0031966 (EC: IEA); GO_0042802 (EC: IEA); GO_0043066 (EC: IEA); GO_0043508 (EC: IEA); GO_0044294 (EC: IEA); GO_0044295 (EC: IEA); GO_0044297 (EC: IEA); GO_0044302 (EC: IEA); GO_0045202 (EC: IEA); GO_0046328 (EC: ISS); GO_0046329 (EC: IEA); GO_0048471 (EC: IEA); GO_2001243 (EC: IEA) PMID: 8619474; 9110174; 9235893; 9442013; 9733513; 9933567; 10490659; 10574993; 10629060; 10700186; 10748095; 10827173; 11147798; 11238452; 11517249; 11585908; 11700324; 11724784; 11726277; 11790792; 11907332; 11912189; 12024021; 12064607; 12194869; 12477932; 12508107; 12524447; 12563035; 12665528; 12740599; 12756254; 12783873; 12893827; 12917434; 12937412; 14507925; 15138488; 15868948; 15894166; 15911620; 15998799; 16169070; 16273093; 16301330; 16456539; 16533805; 16840345; 17200414; 17709393; 18055217; 18286207; 18480379; 19491104; 19616077; 20173330; 20205790; 21237154; 23172226; 23360921; 23770673; 24144296 mitogen-activated protein kinase 8 interacting protein 1 Ensembl:ENSG00000121653 HGNC:6882 HPRD:05223 MIM:604641 Vega:OTTHUMG00000134324 MAPK8IP1 Bin Zhao, Yue Liu, Oliver He ADAMTS-2 ADAMTS-4 ADMP-1 WEB: http://www.ncbi.nlm.nih.gov/gene ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 9507 UNQ769/PRO1563 1q21-q23 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001501 (EC: TAS, PMID: 10356395); GO_0002020 (EC: IPI, PMID: 14744861); GO_0004222 (EC: IEA); GO_0005515 (EC: IPI, PMID: 18718938); GO_0005576 (EC: TAS); GO_0005578 (EC: IEA); GO_0005615 (EC: IDA, PMID: 14744861); GO_0006508 (EC: TAS, PMID: 10751421); GO_0008233 (EC: TAS, PMID: 10751421); GO_0008237 (EC: TAS, PMID: 10356395); GO_0008270 (EC: IEA); GO_0022617 (EC: TAS); GO_0030198 (EC: TAS) PMID: 9734811; 10094461; 10356395; 10438522; 10464288; 10751421; 10801887; 10827174; 10986281; 11167130; 11254106; 11278559; 11796708; 11801682; 11831030; 11854269; 11956193; 12202483; 12477932; 12646579; 12975309; 14561220; 14662755; 14701864; 14715656; 14744861; 15161923; 15489334; 16003758; 16099106; 16188468; 16344560; 16677612; 16710414; 16723216; 16741450; 16771712; 17009305; 17095512; 17208315; 17265492; 17295438; 17311924; 17430884; 17470431; 17606262; 17978660; 18039650; 18042673; 18050214; 18156631; 18221525; 18387286; 18660489; 18671934; 18718938; 18941754; 19054571; 19322201; 19342688; 19643179; 19944557; 20625753; 20664926; 20857147; 21139048; 21334453; 21345877; 21664283; 21946608; 21988832; 22065068; 22324945; 22562232; 22670872; 22735305; 23082219; 23137648; 23295731; 23319426; 23438438; 23897278; 24051360 ADAM metallopeptidase with thrombospondin type 1 motif, 4 HGNC:220 HPRD:04853 MIM:603876 ADAMTS4 Bin Zhao, Yue Liu, Oliver He GDF-15 MIC-1 MIC1 NAG-1 PDF PLAB PTGFB WEB: http://www.ncbi.nlm.nih.gov/gene GDF15 growth differentiation factor 15 9518 19p13.11 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005125 (EC: IEA); GO_0005576 (EC: TAS, PMID: 9326641); GO_0005615 (EC: IEA); GO_0007165 (EC: TAS, PMID: 9326641); GO_0007179 (EC: TAS, PMID: 9348093); GO_0007267 (EC: TAS, PMID: 9326641); GO_0008083 (EC: IEA) PMID: 8125298; 9326641; 9348093; 9375789; 9426002; 9593718; 10524241; 10777512; 10811612; 11102463; 11134143; 11141057; 11259636; 11278594; 11445565; 11895857; 11994274; 12011055; 12082608; 12090982; 12139236; 12477932; 12514175; 12624183; 12855642; 12894347; 12900512; 12941831; 14575402; 14662774; 14726168; 15073115; 15316060; 15342369; 15670751; 15677629; 15757899; 15900300; 16154591; 16286461; 16388506; 16397141; 16484622; 16699947; 16741990; 16775185; 17050687; 17192395; 17328047; 17548705; 17637746; 17721544; 17908975; 17909264; 17982462; 18029348; 18264720; 18359786; 18398830; 18550273; 18624398; 18657084; 18676680; 18754039; 18801729; 18824595; 19047680; 19060904; 19074584; 19100681; 19125423; 19133249; 19152406; 19168526; 19170196; 19302795; 19341722; 19357976; 19375854; 19401523; 19470878; 19505289; 19505919; 19515791; 19521960; 19625176; 19692168; 19695766; 19913121; 19946339; 20024638; 20031597; 20067113; 20104227; 20130018; 20160200; 20167682; 20193126; 20215826; 20237496; 20357380; 20385121; 20431030; 20534737; 20576287; 20628086; 20800603; 20854422; 20855664; 20860541; 20884666; 20937742; 20966402; 20975101; 21097678; 21245963; 21312063; 21336029; 21437897; 21475976; 21487066; 21503121; 21504622; 21535154; 21548946; 21586550; 21616994; 21645023; 21773947; 21803025; 21809352; 21865063; 21881845; 21906983; 22023041; 22064648; 22144502; 22160844; 22180562; 22231869; 22301101; 22341306; 22365732; 22384099; 22484283; 22505696; 22511768; 22723347; 22815297; 22872134; 22975449; 23071585; 23146921; 23154866; 23262134; 23328263; 23335088; 23468844; 23503457; 23799024; 23836903; 23850849; 23996089; 24136234; 24345755 growth differentiation factor 15 Ensembl:ENSG00000130513 HGNC:30142 HPRD:05608 MIM:605312 Vega:OTTHUMG00000183360 GDF15 Bin Zhao, Yue Liu, Oliver He BAG-2 dJ417I1.2 WEB: http://www.ncbi.nlm.nih.gov/gene BAG2 BCL2-associated athanogene 2 9532 RP3-496N17.2 6p12.1-p11.2 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 18457437); GO_0006457 (EC: TAS, PMID: 9873016); GO_0019538 (EC: IDA, PMID: 9873015); GO_0051087 (EC: IEA) PMID: 9873015; 9873016; 11076863; 11230166; 11256614; 12477932; 14574404; 14702039; 15271996; 15489334; 15489336; 16159877; 16169850; 16196087; 16207813; 16344560; 16381901; 17110338; 17203973; 17353931; 17569659; 18457437; 19156129; 19738201; 19875381; 20020773; 20547759; 21081666; 21139048; 21145461; 21906983; 21963094; 21987572; 22365833; 22451720; 22505724; 22863883; 22912744; 23000965; 23275444; 23349634; 23383273; 23398456; 23402259; 23438482; 23455922; 23667531; 23752268; 23824909; 23956138; 24244333; 24255178; 24318877; 24383081 BCL2-associated athanogene 2 HGNC:938 HPRD:04859 MIM:603882 BAG2 Bin Zhao, Yue Liu, Oliver He HB58 Hbeta58 PEP8A VPS26 WEB: http://www.ncbi.nlm.nih.gov/gene VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 9559 10q21.1 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 11102511); GO_0005768 (EC: IDA); GO_0005829 (EC: IDA, PMID: 11102511); GO_0005829 (EC: TAS); GO_0008565 (EC: NAS, PMID: 11102511); GO_0010008 (EC: IEA); GO_0031982 (EC: IDA); GO_0042147 (EC: NAS, PMID: 11102511); GO_0043231 (EC: IDA) PMID: 1638986; 9653160; 11042152; 11102511; 11598206; 12477932; 14702039; 15164054; 15247922; 15282546; 15489334; 16190980; 16196087; 16315276; 16407403; 16732284; 16784798; 17101778; 18781797; 19322201; 19531583; 19738201; 20619655; 20682791; 21139048; 21874001; 21875946; 21890473; 21906983; 21920005; 21963094; 22053931; 22284051; 22354992; 22610502; 22863883; 22939629; 23000965; 23452853; 23455922; 23903356 vacuolar protein sorting 26 homolog A (S. pombe) Ensembl:ENSG00000122958 HGNC:12711 HPRD:08385 MIM:605506 Vega:OTTHUMG00000018376 VPS26A Bin Zhao, Yue Liu, Oliver He N-CoR N-CoR1 TRAC1 hN-CoR WEB: http://www.ncbi.nlm.nih.gov/gene NCOR1 nuclear receptor corepressor 1 9611 17p11.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000118 (EC: IDA, Qualifier: colocalizes_with, PMID: 18326024); GO_0000122 (EC: IMP, PMID: 12628926); GO_0000122 (EC: TAS); GO_0000790 (EC: IDA, PMID: 17505061); GO_0001102 (EC: IPI, PMID: 19955185); GO_0002361 (EC: IEA); GO_0003682 (EC: IEA); GO_0003700 (EC: IEA); GO_0003714 (EC: IDA, PMID: 18052923); GO_0003714 (EC: IMP, PMID: 12628926); GO_0005515 (EC: IPI, PMID: 10049357); GO_0005634 (EC: IC, PMID: 18052923); GO_0005634 (EC: IDA, PMID: 10049357); GO_0005654 (EC: TAS); GO_0005667 (EC: IEA); GO_0005737 (EC: IEA); GO_0005876 (EC: IDA, PMID: 18326024); GO_0006351 (EC: TAS); GO_0006366 (EC: TAS, PMID: 7566114); GO_0006367 (EC: TAS); GO_0007179 (EC: TAS); GO_0007219 (EC: TAS); GO_0010467 (EC: TAS); GO_0014067 (EC: IEA); GO_0016568 (EC: IEA); GO_0016580 (EC: IDA, Qualifier: colocalizes_with, PMID: 11486045); GO_0017053 (EC: IDA, PMID: 11804585); GO_0021794 (EC: IEA); GO_0031065 (EC: IEA); GO_0032922 (EC: IEA); GO_0035033 (EC: IEA); GO_0035257 (EC: IPI, PMID: 9328355); GO_0040014 (EC: IEA); GO_0042632 (EC: IEA); GO_0042826 (EC: IPI, PMID: 11804585); GO_0043565 (EC: IEA); GO_0044212 (EC: ISS); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0046329 (EC: IDA, PMID: 11931768); GO_0046965 (EC: IEA); GO_0046966 (EC: IEA); GO_0051225 (EC: IMP, PMID: 18326024); GO_0060318 (EC: IEA); GO_0072362 (EC: IMP, PMID: 19955185); GO_0072368 (EC: IMP, PMID: 19955185); GO_2000191 (EC: IC, PMID: 19955185) PMID: 7566114; 8948627; 9111334; 9121466; 9328355; 9405624; 9482666; 9486655; 9531570; 9611234; 9694793; 9702189; 9724795; 9751061; 9804773; 9819405; 9849963; 9878542; 10049357; 10077563; 10336495; 10406466; 10441075; 10441327; 10444336; 10470851; 10573424; 10640275; 10675041; 10734313; 10809664; 10860984; 10877839; 10882117; 10898795; 10940306; 10944117; 11001911; 11013263; 11113190; 11124027; 11331609; 11430826; 11439334; 11441023; 11463857; 11466315; 11486045; 11509652; 11533236; 11748154; 11804585; 11865059; 11867749; 11877444; 11889044; 11903058; 11931768; 11971970; 11997503; 12007404; 12011091; 12077342; 12089344; 12089345; 12145334; 12149646; 12150997; 12410313; 12460926; 12466959; 12477932; 12569182; 12590135; 12628926; 12634383; 12648520; 12663743; 12738788; 12764135; 12799135; 12840002; 12861000; 12890497; 12897056; 12904255; 14525983; 14527417; 14593076; 14667819; 14701861; 14702098; 14722073; 14761981; 14985122; 14985366; 15001550; 15016838; 15109542; 15116119; 15131262; 15175761; 15231748; 15256534; 15302935; 15333839; 15336696; 15377655; 15454082; 15531890; 15536134; 15561719; 15572376; 15598662; 15601853; 15604093; 15681609; 15695367; 15729358; 15761026; 15788656; 15802375; 15829968; 15832170; 15870285; 15878880; 15934135; 16024608; 16024779; 16030140; 16033423; 16121196; 16127449; 16141343; 16147992; 16195251; 16216492; 16227606; 16252006; 16373395; 16421255; 16464943; 16469706; 16712523; 16713569; 16730330; 16849648; 16914745; 16917504; 16964243; 17018285; 17073437; 17079677; 17081983; 17182846; 17210713; 17242407; 17255935; 17373667; 17400812; 17416745; 17440114; 17468099; 17468742; 17505061; 17519354; 17572682; 17620012; 17630505; 17768398; 18052923; 18202150; 18206970; 18292238; 18326024; 18362166; 18586123; 18632669; 18637017; 18660489; 18669643; 18829436; 18832723; 18852122; 18978041; 19011633; 19032343; 19048289; 19064572; 19098224; 19126649; 19147702; 19183483; 19211732; 19244234; 19414341; 19471022; 19608741; 19781322; 19913121; 19955185; 20003447; 20181716; 20466759; 20581824; 20587609; 20628086; 20812024; 20935208; 20974212; 21081666; 21088000; 21131350; 21139048; 21143702; 21258344; 21331046; 21389087; 21518914; 21525722; 21527249; 21532573; 21693764; 21890473; 21963094; 21966475; 21987803; 21988832; 22078880; 22190034; 22294699; 22337871; 22349439; 22514634; 22622808; 22651256; 22675025; 22939629; 22944139; 23129261; 23295231; 23428870; 23518348; 23667531; 23752268; 23940660; 24315104 nuclear receptor corepressor 1 Ensembl:ENSG00000141027 HGNC:7672 HPRD:02911 MIM:600849 Vega:OTTHUMG00000059309 NCOR1 Bin Zhao, Yue Liu, Oliver He CTG26 N-CoR2 SMAP270 SMRT SMRTE SMRTE-tau TNRC14 TRAC TRAC-1 TRAC1 WEB: http://www.ncbi.nlm.nih.gov/gene NCOR2 nuclear receptor corepressor 2 9612 12q24 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000122 (EC: IDA, PMID: 10097068); GO_0000122 (EC: IMP, PMID: 12628926); GO_0000122 (EC: TAS); GO_0003677 (EC: IEA); GO_0003682 (EC: IEA); GO_0003714 (EC: IDA, PMID: 18052923); GO_0003714 (EC: IMP, PMID: 12628926); GO_0005112 (EC: IPI, PMID: 10713164); GO_0005515 (EC: IPI, PMID: 10395741); GO_0005634 (EC: IC, PMID: 18052923); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0006351 (EC: TAS); GO_0006367 (EC: TAS); GO_0007179 (EC: TAS); GO_0007219 (EC: TAS); GO_0010467 (EC: TAS); GO_0016363 (EC: IDA); GO_0016604 (EC: IDA, PMID: 16030140); GO_0017053 (EC: IDA, PMID: 11804585); GO_0042826 (EC: IPI, PMID: 11804585); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0047485 (EC: IPI, PMID: 16893456); GO_0072365 (EC: IMP, PMID: 19955185) PMID: 7566114; 7566127; 8813722; 8889548; 9171229; 9225980; 9256429; 9267036; 9380707; 9405624; 9415406; 9486654; 9702189; 9751500; 9765306; 9819405; 9878542; 10049357; 10077563; 10082574; 10097068; 10395741; 10406466; 10611298; 10640275; 10640276; 10644367; 10713164; 10757795; 10777532; 10809664; 10860984; 10869435; 10898795; 10944117; 11013263; 11113190; 11134019; 11158331; 11259580; 11331609; 11404076; 11430826; 11435691; 11466315; 11509652; 11509665; 11518802; 11559707; 11585900; 11726519; 11739383; 11804585; 11845213; 11865059; 11867749; 11923464; 11929748; 11929749; 11931768; 11959865; 11972046; 11997503; 12007404; 12011091; 12072427; 12107410; 12139968; 12205093; 12242670; 12388540; 12441355; 12460926; 12477932; 12502735; 12554770; 12589049; 12628926; 12665583; 12738788; 12771131; 12840002; 12904255; 12970571; 14527417; 14593076; 14690607; 14715875; 14982881; 14985122; 15016838; 15016912; 15062576; 15146197; 15175761; 15231748; 15300237; 15302935; 15319284; 15454082; 15494311; 15531890; 15536134; 15604093; 15632172; 15635693; 15681609; 15713534; 15729358; 15802375; 15832170; 15837933; 15843525; 15870285; 15878880; 16002533; 16024608; 16030140; 16033423; 16042694; 16121196; 16129689; 16144941; 16147992; 16219912; 16373395; 16382138; 16453284; 16480812; 16481466; 16613989; 16712523; 16893456; 16924111; 16956611; 17000644; 17043677; 17073437; 17081983; 17126328; 17242407; 17347654; 17356171; 17383980; 17475621; 17560331; 17902051; 17991421; 18029348; 18052923; 18187620; 18212045; 18347093; 18362166; 18487509; 18546531; 18632669; 18660489; 18838553; 18852122; 18950845; 19098224; 19144721; 19183483; 19211732; 19223455; 19244234; 19417136; 19432593; 19471022; 19596686; 19617623; 19730683; 19734545; 19851296; 19904269; 19934400; 19955185; 20003447; 20195357; 20198315; 20364085; 20392877; 20555024; 20812024; 20935208; 20965228; 21081666; 21083371; 21088000; 21131350; 21139048; 21143702; 21240272; 21258344; 21282530; 21518914; 21532573; 21624135; 21693764; 22185585; 22230954; 22292036; 22294699; 22337871; 22508987; 22576662; 22695118; 22944139; 23015261; 23055525; 23117886; 23221346; 23225884; 23562850; 23648065; 23690919; 23752268; 23861398; 23958962 nuclear receptor corepressor 2 Ensembl:ENSG00000196498 HGNC:7673 HPRD:02910 MIM:600848 Vega:OTTHUMG00000150455 NCOR2 Bin Zhao, Yue Liu, Oliver He KIAA0652 PARATARG8 WEB: http://www.ncbi.nlm.nih.gov/gene ATG13 autophagy related 13 9776 11p11.2 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0000045 (EC: IMP, PMID: 19211835); GO_0000407 (EC: ISS); GO_0005515 (EC: IPI, PMID: 19211835); GO_0005829 (EC: IEA); GO_0019901 (EC: IPI, PMID: 18936157); GO_0070969 (EC: IPI, PMID: 19211835) PMID: 8125298; 8619474; 9110174; 9734811; 12107413; 12477932; 14702039; 15489334; 16196087; 16344560; 17204848; 17207965; 18936157; 19211835; 19225151; 19258318; 19287211; 19597335; 19690328; 20562859; 20694011; 21460630; 21475306; 21832049; 21900206; 21976705; 23043107; 23524951; 24100292 autophagy related 13 Ensembl:ENSG00000175224 HGNC:29091 HPRD:13809 MIM:615088 Vega:OTTHUMG00000166538 ATG13 Bin Zhao, Yue Liu, Oliver He PRO2463 WEB: http://www.ncbi.nlm.nih.gov/gene NUPL1 nucleoporin like 1 9818 RP11-206I15.1 13q12.13 20140408 9606 13 protein-coding Official from a nomenclature committee GO_0000278 (EC: TAS); GO_0005487 (EC: IEA); GO_0005515 (EC: IPI, PMID: 17500595); GO_0005635 (EC: TAS); GO_0005643 (EC: IEA); GO_0005975 (EC: TAS); GO_0007077 (EC: TAS); GO_0008645 (EC: TAS); GO_0010827 (EC: TAS); GO_0015031 (EC: IEA); GO_0015758 (EC: TAS); GO_0016032 (EC: TAS); GO_0019221 (EC: TAS); GO_0031965 (EC: IEA); GO_0044281 (EC: TAS); GO_0051028 (EC: IEA); GO_0055085 (EC: TAS) PMID: 7531196; 8889548; 9455477; 10601273; 11266456; 12228227; 12477932; 14702039; 15342556; 15489334; 17500595; 20936779; 21139048; 21890473; 21900206; 21906983; 22505724; 22939629; 23000965; 23275563; 23383273 nucleoporin like 1 Ensembl:ENSG00000139496 HGNC:20261 HPRD:06355 MIM:607615 Vega:OTTHUMG00000016608 NUPL1 Bin Zhao, Yue Liu, Oliver He ATG17 CC1 FIP200 WEB: http://www.ncbi.nlm.nih.gov/gene RB1CC1 RB1-inducible coiled-coil 1 9821 8q11 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0000045 (EC: IEA); GO_0001889 (EC: IEA); GO_0001934 (EC: IEA); GO_0005515 (EC: IPI, PMID: 19211835); GO_0005737 (EC: IDA); GO_0005829 (EC: IEA); GO_0006351 (EC: IEA); GO_0006355 (EC: IEA); GO_0007049 (EC: IEA); GO_0007254 (EC: IEA); GO_0007507 (EC: IEA); GO_0010506 (EC: ISS); GO_0019901 (EC: IEA); GO_0031965 (EC: IDA); GO_0034045 (EC: ISS); GO_0043066 (EC: IEA); GO_0045793 (EC: IEA); GO_0070969 (EC: IPI, PMID: 19211835); GO_2001237 (EC: IEA) PMID: 7724523; 9039502; 10769033; 11850849; 12068296; 12095676; 12163359; 12221124; 12477932; 14533007; 15375585; 15489334; 15968549; 16043512; 16061648; 16344560; 16865226; 17015619; 17081983; 17353931; 17706618; 17707572; 17986458; 18036779; 18285457; 18443221; 18676680; 18976975; 19170196; 19211835; 19225151; 19258318; 19437535; 19625176; 19690328; 19692168; 19888451; 20301425; 20453000; 20562859; 20614030; 21139048; 21203526; 21602932; 21637919; 21717524; 21775823; 21795712; 21822266; 21903422; 21988832; 22049074; 22396748; 22751121; 23043107; 23262492; 23289756; 23602568; 23885119; 24100292; 24250222 RB1-inducible coiled-coil 1 Ensembl:ENSG00000023287 HGNC:15574 HPRD:06019 MIM:606837 Vega:OTTHUMG00000164268 RB1CC1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene GAB2 GRB2-associated binding protein 2 9846 11q14.1 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0005068 (EC: IDA, PMID: 19172738); GO_0005070 (EC: RCA, PMID: 19641626); GO_0005515 (EC: IPI, PMID: 15170389); GO_0005547 (EC: ISS); GO_0005737 (EC: IDA, PMID: 19172738); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 19172738); GO_0007169 (EC: IDA, PMID: 19172738); GO_0008284 (EC: IDA, PMID: 19172738); GO_0009967 (EC: RCA, PMID: 19641626); GO_0030316 (EC: IMP, PMID: 15750601); GO_0038095 (EC: TAS); GO_0043306 (EC: ISS); GO_0043325 (EC: ISS); GO_0045087 (EC: TAS); GO_0048015 (EC: ISS) PMID: 9628581; 10068651; 10391903; 10455108; 10704825; 10752981; 10871282; 10913131; 11287610; 11334882; 11402314; 11466412; 11572860; 11701952; 11782427; 11812650; 11830491; 11882361; 11895767; 11971018; 11997510; 12008033; 12135708; 12140767; 12176364; 12477932; 12522270; 12819203; 14530346; 14687710; 14982882; 15010462; 15143164; 15170389; 15356145; 15574337; 15750601; 15952937; 16135792; 16219545; 16253990; 16344560; 16368877; 16369543; 16736498; 17553421; 17998934; 18235045; 18272374; 18314909; 18644434; 18697750; 18853460; 18854865; 19118819; 19172738; 19204163; 19233262; 19262956; 19276544; 19342374; 19380743; 19509136; 19523899; 19608861; 19641626; 19838208; 19881546; 19909739; 19913121; 19924507; 20087860; 20188796; 20237496; 20413850; 20534741; 20574532; 20628086; 20634593; 20697350; 20888920; 20936779; 21102462; 21108942; 21118992; 21285854; 21552417; 21653832; 21706016; 21996746; 22851227; 22856364; 22859374; 22883624; 22926523; 23401857; 23525328; 23724096; 24161894; 24385586 GRB2-associated binding protein 2 GAB2 Bin Zhao, Yue Liu, Oliver He GFAT2 WEB: http://www.ncbi.nlm.nih.gov/gene GFPT2 glutamine-fructose-6-phosphate transaminase 2 9945 5q34-q35 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0004360 (EC: IEA); GO_0005829 (EC: TAS); GO_0006002 (EC: TAS, PMID: 10198162); GO_0006048 (EC: IEA); GO_0006048 (EC: TAS); GO_0006112 (EC: TAS, PMID: 10198162); GO_0006488 (EC: TAS); GO_0006541 (EC: IEA); GO_0016051 (EC: IEA); GO_0018279 (EC: TAS); GO_0030246 (EC: IEA); GO_0043687 (EC: TAS); GO_0044267 (EC: TAS) PMID: 10198162; 12477932; 14702039; 14764791; 15489334; 17081983; 17542649; 17574229; 20353610; 20881960; 21044950; 21145461; 21897333; 21906983; 22505724; 23314748 glutamine-fructose-6-phosphate transaminase 2 Ensembl:ENSG00000131459 HGNC:4242 HPRD:04842 MIM:603865 Vega:OTTHUMG00000163442 GFPT2 Bin Zhao, Yue Liu, Oliver He ARC240 CAGH45 FGS1 HOPA MED12S OHDOX OKS OPA1 TNRC11 TRAP230 WEB: http://www.ncbi.nlm.nih.gov/gene MED12 mediator complex subunit 12 9968 Xq13 20140408 9606 X protein-coding Official from a nomenclature committee GO_0000980 (EC: IEA); GO_0001104 (EC: IDA, PMID: 10198638); GO_0001190 (EC: IEA); GO_0001843 (EC: IEA); GO_0003682 (EC: IEA); GO_0003712 (EC: IDA, PMID: 12218053); GO_0003713 (EC: IDA, PMID: 12037571); GO_0004872 (EC: IDA, PMID: 12218053); GO_0005515 (EC: IPI); GO_0005634 (EC: IDA, PMID: 10235267); GO_0005654 (EC: TAS); GO_0006367 (EC: IDA, PMID: 12218053); GO_0006367 (EC: TAS); GO_0007507 (EC: IEA); GO_0008013 (EC: IEA); GO_0008022 (EC: IPI, PMID: 17000779); GO_0010467 (EC: TAS); GO_0014003 (EC: IEA); GO_0014044 (EC: IEA); GO_0016592 (EC: IDA, PMID: 10198638); GO_0019827 (EC: IEA); GO_0019904 (EC: IPI, PMID: 11984006); GO_0030178 (EC: IMP, PMID: 17000779); GO_0030374 (EC: NAS, PMID: 10235266); GO_0030518 (EC: IDA, PMID: 11867769); GO_0030521 (EC: IDA, PMID: 12218053); GO_0042809 (EC: NAS, PMID: 10235266); GO_0045893 (EC: IDA, PMID: 10198638); GO_0045944 (EC: IDA, PMID: 12037571); GO_0046966 (EC: IDA, PMID: 10198638); GO_0060070 (EC: IEA); GO_0060071 (EC: IEA); GO_0090245 (EC: IEA) PMID: 8710870; 8724849; 8781769; 8889548; 9225980; 9375929; 9702738; 10198638; 10235266; 10235267; 10480376; 10882111; 11424983; 11524702; 11834832; 11840515; 11867769; 11984006; 12037571; 12136106; 12216017; 12218053; 12477932; 12584197; 12612078; 12627458; 12660246; 12777533; 12860370; 14636573; 14638676; 14657022; 15108174; 15175163; 15717329; 15989967; 16109376; 16344560; 16538184; 16565090; 16799563; 17000779; 17081983; 17088561; 17110338; 17299734; 17334363; 17369503; 17716226; 17967894; 18029348; 18418385; 18691967; 18973276; 19036726; 19047373; 19240132; 19596686; 20098423; 20133760; 20301719; 20507344; 20508642; 20720539; 21139048; 21293490; 21729782; 21868628; 21890473; 21963094; 21987572; 22182697; 22223266; 22428002; 22505724; 22532225; 22586326; 22768200; 22939629; 23091001; 23132392; 23178117; 23222489; 23225304; 23275444; 23322298; 23347103; 23395478; 23517922; 23563140; 23602568; 23635816; 23661306; 23913526; 24163370; 24196187; 24457600 mediator complex subunit 12 Ensembl:ENSG00000184634 HGNC:11957 HPRD:02176 MIM:300188 Vega:OTTHUMG00000021788 MED12 Bin Zhao, Yue Liu, Oliver He SRA SRAP STRAA1 pp7684 WEB: http://www.ncbi.nlm.nih.gov/gene SRA1 steroid receptor RNA activator 1 10011 PP7684 5q31.3 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0003677 (EC: IEA); GO_0003713 (EC: IDA, PMID: 10199399); GO_0005515 (EC: IPI, PMID: 16595694); GO_0005634 (EC: IDA); GO_0005667 (EC: IEA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005886 (EC: IDA); GO_0006351 (EC: IEA); GO_0006915 (EC: IEA); GO_0008283 (EC: IDA, PMID: 14517287); GO_0010861 (EC: IEA); GO_0015630 (EC: IDA); GO_0030154 (EC: IDA, PMID: 14517287); GO_0030374 (EC: IBA); GO_0030529 (EC: IPI, PMID: 10199399); GO_0031252 (EC: IEA); GO_0042981 (EC: IDA, PMID: 14517287); GO_0045171 (EC: IDA); GO_0045944 (EC: IEA); GO_2000273 (EC: IBA) PMID: 10199399; 10485452; 11103781; 11250900; 11331609; 11438648; 11818499; 12118039; 12163482; 12444263; 12477932; 12565891; 12909012; 12943696; 14517287; 14702039; 14715875; 15147866; 15180993; 15327771; 15351741; 15489334; 15498874; 15607539; 16152589; 16169070; 16344560; 16540468; 16595694; 16607388; 16773180; 16848684; 17702747; 18676680; 18827892; 18950845; 19064572; 19064678; 19188450; 19483093; 19625176; 19692168; 19740422; 20079837; 20153324; 20219889; 20398657; 20677014; 20855289; 20966046; 21771633; 21790861; 21807064; 21906983; 22362738; 22939629; 22998747; 23907597 steroid receptor RNA activator 1 Ensembl:ENSG00000213523 HGNC:11281 HPRD:18716 MIM:603819 Vega:OTTHUMG00000163569 SRA1 Bin Zhao, Yue Liu, Oliver He LXR-a LXRA RLD-1 WEB: http://www.ncbi.nlm.nih.gov/gene NR1H3 nuclear receptor subfamily 1, group H, member 3 10062 11p11.2 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0000122 (EC: ISS); GO_0000790 (EC: IDA, PMID: 18511497); GO_0003677 (EC: TAS, PMID: 7744246); GO_0003707 (EC: IEA); GO_0003713 (EC: TAS, PMID: 7744246); GO_0004879 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12040021); GO_0005634 (EC: TAS, PMID: 7744246); GO_0005654 (EC: TAS); GO_0006367 (EC: TAS); GO_0008270 (EC: IEA); GO_0010467 (EC: TAS); GO_0010745 (EC: IC, PMID: 17693624); GO_0010867 (EC: IMP, PMID: 17693624); GO_0010870 (EC: IDA, PMID: 18511497); GO_0010875 (EC: IDA, PMID: 16141411); GO_0010875 (EC: IMP, PMID: 17186944); GO_0010887 (EC: IMP, PMID: 17693624); GO_0015485 (EC: TAS, PMID: 11090131); GO_0032270 (EC: IMP, PMID: 17186944); GO_0032369 (EC: IMP, PMID: 17693624); GO_0032376 (EC: IDA, PMID: 16141411); GO_0032570 (EC: IDA, PMID: 16141411); GO_0032810 (EC: IDA, PMID: 19628791); GO_0034145 (EC: IDA, PMID: 18511497); GO_0042632 (EC: ISS); GO_0042752 (EC: TAS, PMID: 18511497); GO_0043031 (EC: ISS); GO_0043277 (EC: IMP, PMID: 19628791); GO_0043565 (EC: IEA); GO_0044212 (EC: IDA, PMID: 19229075); GO_0044212 (EC: IDA, Qualifier: contributes_to, PMID: 18511497); GO_0044255 (EC: IEA); GO_0045723 (EC: IMP, PMID: 17186944); GO_0045861 (EC: IEA); GO_0045893 (EC: IMP, PMID: 19628791); GO_0045944 (EC: IDA, PMID: 16141411); GO_0045944 (EC: IMP, PMID: 17186944); GO_0048550 (EC: IMP, PMID: 17693624); GO_0050728 (EC: ISS); GO_0051006 (EC: IMP, PMID: 17186944); GO_0055088 (EC: ISS); GO_0055092 (EC: ISS); GO_0060336 (EC: NAS); GO_0070328 (EC: ISS); GO_0071222 (EC: IDA, PMID: 18511497); GO_0090188 (EC: ISS); GO_0090341 (EC: ISS); GO_2000188 (EC: ISS); GO_2000189 (EC: IDA, PMID: 18511497) PMID: 7744246; 8510758; 8621574; 9013544; 9231657; 9630215; 10022764; 11035776; 11090131; 11135616; 11149950; 11875109; 12032151; 12040021; 12054659; 12117567; 12161442; 12198243; 12470296; 12477932; 12663743; 12724417; 12932788; 12957674; 14699103; 14702039; 15319359; 15342556; 15353176; 15489334; 15489335; 15539633; 15548517; 15604093; 15615782; 15625283; 16054077; 16106051; 16141411; 16143103; 16170053; 16249184; 16341674; 16344560; 16354658; 16482468; 16567856; 16758300; 16904112; 16920108; 16941683; 16956579; 16973760; 17108812; 17110595; 17135302; 17186944; 17217555; 17218271; 17255360; 17272748; 17296605; 17391100; 17396233; 17405904; 17416342; 17452725; 17628006; 17644777; 17693624; 17724434; 17766241; 17845217; 17936707; 17960176; 18007013; 18024509; 18096827; 18182682; 18209740; 18250151; 18276933; 18327405; 18372238; 18511497; 18562803; 18636124; 18660489; 18669643; 18789440; 18854425; 19060910; 19105208; 19119143; 19164445; 19201410; 19211025; 19229075; 19261092; 19292929; 19360318; 19366697; 19380774; 19426978; 19436111; 19481530; 19628791; 19645823; 19697157; 19796621; 19798078; 19837721; 19913121; 19933273; 20005944; 20037595; 20057170; 20080977; 20118482; 20139031; 20190811; 20211142; 20219900; 20237496; 20364260; 20410489; 20494359; 20506155; 20628086; 20655109; 20686565; 20836841; 20837115; 20855565; 20868688; 20945144; 21042792; 21125317; 21136146; 21187453; 21245992; 21266776; 21310851; 21315073; 21316679; 21349840; 21350215; 21356276; 21440016; 21562465; 21625070; 21775116; 21832049; 21889884; 21903943; 21937108; 21951066; 21988832; 22027013; 22137263; 22257474; 22311022; 22367754; 22399489; 22399527; 22457708; 22503545; 22547570; 22569763; 22610535; 22623531; 22634718; 22641099; 22707265; 22723445; 22749359; 22766509; 22916038; 22939624; 22969086; 22984430; 22990668; 23018104; 23041609; 23099324; 23163651; 23185273; 23313547; 23393188; 23416078; 23451202; 23455924; 23496987; 23564066; 23680128; 23732298; 23733886; 23838803; 23867395; 24009820; 24036496; 24100084 nuclear receptor subfamily 1, group H, member 3 Ensembl:ENSG00000025434 HGNC:7966 HPRD:07211 MIM:602423 Vega:OTTHUMG00000150628 NR1H3 Bin Zhao, Yue Liu, Oliver He ARL7 LAK WEB: http://www.ncbi.nlm.nih.gov/gene ARL4C ADP-ribosylation factor-like 4C 10123 2q37.1 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0003924 (EC: TAS, PMID: 10462049); GO_0005515 (EC: IPI, PMID: 17398095); GO_0005525 (EC: IEA); GO_0005634 (EC: TAS, PMID: 10462049); GO_0005737 (EC: IDA); GO_0005886 (EC: IDA); GO_0006184 (EC: TAS, PMID: 10462049); GO_0007264 (EC: IEA); GO_0030175 (EC: IEA); GO_0032456 (EC: IDA, PMID: 19409876); GO_0043014 (EC: IDA, PMID: 19409876) PMID: 10462049; 12477932; 15147902; 15489334; 16713569; 17398095; 18029348; 19409876; 20686608; 21187453; 21832049; 21890473; 21906983; 21963094; 23000965 ADP-ribosylation factor-like 4C Ensembl:ENSG00000188042 HGNC:698 HPRD:11988 MIM:604787 Vega:OTTHUMG00000133291 ARL4C Bin Zhao, Yue Liu, Oliver He BMP-11 BMP11 WEB: http://www.ncbi.nlm.nih.gov/gene GDF11 growth differentiation factor 11 10220 12q13.2 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0001501 (EC: TAS, PMID: 10391213); GO_0001656 (EC: IEA); GO_0001657 (EC: IEA); GO_0005125 (EC: IEA); GO_0005575 (EC: ND); GO_0005615 (EC: IEA); GO_0007399 (EC: TAS, PMID: 10075854); GO_0007498 (EC: TAS, PMID: 10075854); GO_0008083 (EC: IEA); GO_0008285 (EC: IEA); GO_0021512 (EC: IEA); GO_0031016 (EC: IEA); GO_0040007 (EC: IEA); GO_0045596 (EC: IEA); GO_0048469 (EC: IEA); GO_0048593 (EC: IEA) PMID: 8889549; 10075854; 10391213; 10508689; 15988002; 16845371; 17912435; 17997109; 18519639; 18535106; 18596030; 19751112; 20734064 growth differentiation factor 11 Ensembl:ENSG00000135414 HGNC:4216 HPRD:04895 MIM:603936 Vega:OTTHUMG00000170188 GDF11 Bin Zhao, Yue Liu, Oliver He CHIP HSPABP2 NY-CO-7 SDCCAG7 UBOX1 WEB: http://www.ncbi.nlm.nih.gov/gene STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 10273 LA16c-313D11.6 16p13.3 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0000151 (EC: IDA, PMID: 16275660); GO_0000209 (EC: IDA, PMID: 15781469); GO_0000209 (EC: IMP, PMID: 19713937); GO_0004842 (EC: IDA, PMID: 15466472); GO_0004842 (EC: IMP, PMID: 19713937); GO_0004842 (EC: TAS, PMID: 16307917); GO_0005515 (EC: IPI, PMID: 11146632); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA); GO_0006281 (EC: IEA); GO_0006511 (EC: IMP, PMID: 19713937); GO_0006515 (EC: IDA, PMID: 16831871); GO_0007179 (EC: TAS); GO_0019899 (EC: IPI, PMID: 16280320); GO_0019900 (EC: IPI, PMID: 17512523); GO_0030512 (EC: TAS); GO_0030544 (EC: IDA, PMID: 10330192); GO_0030579 (EC: IDA, PMID: 15781469); GO_0030674 (EC: TAS, PMID: 16307917); GO_0030911 (EC: IDA, PMID: 11146632); GO_0031371 (EC: TAS, PMID: 16307917); GO_0031398 (EC: IDA, PMID: 11146632); GO_0031625 (EC: IEA); GO_0031943 (EC: IDA, PMID: 11146632); GO_0032436 (EC: IDA, PMID: 11146632); GO_0034450 (EC: ISS); GO_0042405 (EC: IDA, PMID: 16831871); GO_0042803 (EC: ISS); GO_0043161 (EC: IDA, PMID: 15781469); GO_0045111 (EC: IDA); GO_0046332 (EC: IDA, PMID: 15781469); GO_0051604 (EC: TAS, PMID: 16307917); GO_0051787 (EC: IDA, PMID: 16831871); GO_0051865 (EC: IDA, PMID: 16307917); GO_0051879 (EC: IDA, PMID: 11146632); GO_0070534 (EC: IDA, PMID: 16307917); GO_0071218 (EC: IDA, PMID: 16831871); GO_0090035 (EC: IDA, PMID: 16831871) PMID: 9610721; 10330192; 11146632; 11146634; 11157797; 11557750; 11676916; 11743028; 11805346; 12150907; 12200376; 12239347; 12477932; 12559985; 12574167; 12837759; 14532117; 14532270; 14612456; 14701756; 14962978; 15001357; 15046863; 15107424; 15189447; 15198682; 15215316; 15254225; 15302935; 15358145; 15447663; 15456869; 15466472; 15489334; 15525661; 15538384; 15611333; 15694383; 15708501; 15761032; 15761153; 15781469; 15911628; 15936278; 16037132; 16038411; 16111477; 16135753; 16169070; 16169850; 16207813; 16275660; 16280320; 16293251; 16307917; 16621797; 16682404; 16712791; 16714300; 16720573; 16725394; 16740632; 16809764; 16831871; 16895519; 16964243; 17081983; 17127076; 17157513; 17178836; 17209571; 17239458; 17304350; 17317785; 17324930; 17512523; 17545168; 17595347; 17666403; 17873020; 17875712; 17962192; 17963781; 18042044; 18094050; 18223694; 18292230; 18313385; 18388150; 18411298; 18436529; 18457437; 18485199; 18541707; 18655187; 18678647; 18718056; 18784277; 18818696; 18955503; 18988734; 19011619; 19056735; 19098309; 19103148; 19153604; 19165527; 19196961; 19198599; 19237536; 19240029; 19306926; 19362296; 19406989; 19465479; 19471022; 19478201; 19483080; 19524548; 19536328; 19648119; 19706771; 19713937; 19818709; 19875381; 19892702; 19913553; 19940151; 20029029; 20146531; 20151404; 20349136; 20413784; 20466727; 20588253; 20618441; 20661446; 20675402; 20677910; 20704274; 20724525; 20729196; 20811636; 20924358; 20943656; 20947504; 20947508; 20959453; 20974249; 20974815; 21044950; 21124777; 21139048; 21157430; 21209460; 21220432; 21268072; 21272160; 21293491; 21325980; 21358815; 21360678; 21454478; 21518764; 21549100; 21625540; 21652633; 21710689; 21767636; 21775628; 21793045; 21855799; 21860411; 21898230; 21911421; 21942715; 21988832; 21995445; 22038067; 22090276; 22101235; 22118674; 22128174; 22190034; 22190037; 22254155; 22271573; 22350907; 22350919; 22407479; 22427670; 22433856; 22492994; 22535373; 22543587; 22551455; 22670667; 22734001; 22824801; 22842904; 22863883; 22895543; 22939629; 23023377; 23109339; 23134341; 23237806; 23246967; 23256568; 23271055; 23322406; 23344957; 23410750; 23412384; 23431407; 23455922; 23482560; 23493285; 23554879; 23560854; 23602568; 23629654; 23679257; 23686137; 23729439; 23764847; 23865999; 23880665; 23904609; 23963841; 23973223; 23990462; 24023840; 24043303; 24250222; 24509416 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase Ensembl:ENSG00000103266 HGNC:11427 HPRD:06232 MIM:607207 Vega:OTTHUMG00000121140 STUB1 Bin Zhao, Yue Liu, Oliver He IMAC MIP-4a MIP-4alpha SCYA26 TSC-1 WEB: http://www.ncbi.nlm.nih.gov/gene CCL26 chemokine (C-C motif) ligand 26 10344 UNQ216/PRO242 7q11.23 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0001938 (EC: IDA, PMID: 19525930); GO_0005615 (EC: IEA); GO_0006935 (EC: TAS, PMID: 10373330); GO_0006954 (EC: IEA); GO_0006955 (EC: IEA); GO_0007165 (EC: NAS, PMID: 10373330); GO_0007267 (EC: TAS, PMID: 10373330); GO_0008009 (EC: IEA); GO_0030335 (EC: IDA, PMID: 19525930); GO_0030838 (EC: IDA, PMID: 19525930); GO_0032855 (EC: IDA, PMID: 19525930); GO_0060326 (EC: TAS, PMID: 10373330) PMID: 9847074; 10373330; 10415065; 10488147; 11329013; 11425309; 11544308; 11748272; 12061839; 12192108; 12477932; 12689946; 12853948; 12975309; 15039444; 15207712; 15489334; 15521376; 15784470; 15863444; 16084752; 16264039; 16391516; 16453027; 16604488; 17073866; 17490641; 17541284; 17703412; 17900656; 18055844; 18712274; 18774776; 18844613; 19141347; 19141349; 19203252; 19258923; 19331716; 19379605; 19423540; 19525930; 19567623; 20056178; 20059579; 20143648; 20236835; 20406964; 20438785; 20503287; 20505746; 20974991; 21077277; 21266446; 21303604; 21325281; 21493274; 21832049; 21881593; 21985360; 22226123; 22580413; 22739041; 22846146; 22946025; 22948508; 22952702; 23185525; 23477905; 23532518; 23607908; 24323578; 24600981 chemokine (C-C motif) ligand 26 Ensembl:ENSG00000006606 HGNC:10625 HPRD:05262 MIM:604697 Vega:OTTHUMG00000130403 CCL26 Bin Zhao, Yue Liu, Oliver He ABCA-SSN ABCX WEB: http://www.ncbi.nlm.nih.gov/gene ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 10347 19p13.3 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000139 (EC: IEA); GO_0005215 (EC: TAS, PMID: 10873640); GO_0005524 (EC: IEA); GO_0005548 (EC: IEA); GO_0005737 (EC: IDA); GO_0005794 (EC: IDA); GO_0005886 (EC: IDA); GO_0005886 (EC: TAS); GO_0006909 (EC: IEA); GO_0010008 (EC: IEA); GO_0016021 (EC: TAS, PMID: 10873640); GO_0016324 (EC: IEA); GO_0016887 (EC: IEA); GO_0033700 (EC: IEA); GO_0043190 (EC: TAS, PMID: 10873640); GO_0055085 (EC: TAS) PMID: 8889548; 10873640; 11054552; 11095984; 11355874; 11435699; 12111378; 12917409; 12925201; 14570867; 14592415; 14702039; 15203218; 15593299; 15930518; 16908670; 18029348; 18676680; 19170196; 19343046; 19625176; 19692168; 19721717; 19913121; 20628086; 20855565; 21173549; 21460840; 21460841; 21906983; 23324282; 23571587; 23669301; 24097981; 24141082 ATP-binding cassette, sub-family A (ABC1), member 7 Ensembl:ENSG00000064687 HGNC:37 HPRD:09255 MIM:605414 Vega:OTTHUMG00000167547 ABCA7 Bin Zhao, Yue Liu, Oliver He CARD4 CLR7.1 NLRC1 WEB: http://www.ncbi.nlm.nih.gov/gene NOD1 nucleotide-binding oligomerization domain containing 1 10392 7p15-p14 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0000187 (EC: TAS); GO_0002224 (EC: TAS); GO_0002606 (EC: ISS); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0005515 (EC: IPI, PMID: 15107016); GO_0005524 (EC: IEA); GO_0005737 (EC: IDA, PMID: 10329646); GO_0005737 (EC: TAS, PMID: 15967716); GO_0005829 (EC: TAS); GO_0006915 (EC: TAS, PMID: 10329646); GO_0006919 (EC: IDA, PMID: 10329646); GO_0006952 (EC: TAS, PMID: 15967716); GO_0006954 (EC: TAS, PMID: 15967716); GO_0007165 (EC: TAS, PMID: 15967716); GO_0007254 (EC: TAS); GO_0008656 (EC: TAS, PMID: 10329646); GO_0009595 (EC: TAS, PMID: 15967716); GO_0016045 (EC: IDA, PMID: 15653568); GO_0016323 (EC: IDA, PMID: 19043560); GO_0016324 (EC: IEA); GO_0032755 (EC: IEA); GO_0032760 (EC: IEA); GO_0034134 (EC: TAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035556 (EC: IDA, PMID: 15653568); GO_0035666 (EC: TAS); GO_0035872 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042228 (EC: IDA, PMID: 15653568); GO_0042742 (EC: IDA, PMID: 15653568); GO_0042802 (EC: IDA, PMID: 10329646); GO_0042802 (EC: IPI, PMID: 18186648); GO_0042803 (EC: IPI, PMID: 18186648); GO_0042834 (EC: TAS, PMID: 15967716); GO_0043123 (EC: IDA, PMID: 10329646); GO_0043280 (EC: IDA, PMID: 10329646); GO_0045087 (EC: TAS); GO_0046330 (EC: IEA); GO_0050700 (EC: IDA, PMID: 10329646); GO_0050830 (EC: IEA); GO_0051092 (EC: IDA, PMID: 17054981); GO_0051092 (EC: TAS); GO_0051259 (EC: TAS, PMID: 15967716); GO_0051403 (EC: TAS); GO_0070374 (EC: IEA); GO_0070423 (EC: TAS) PMID: 10224040; 10329646; 10880512; 11058605; 11113115; 12459189; 12477932; 12690205; 12761501; 12775719; 12791997; 12813035; 12853948; 12871942; 14702039; 14977954; 15107016; 15276183; 15489334; 15653568; 15657077; 15718249; 15790594; 15967716; 15990792; 16083881; 16115863; 16172124; 16260731; 16446438; 16464805; 16493424; 16517750; 16741608; 16893397; 16918516; 16935475; 17005562; 17012967; 17030188; 17054981; 17100974; 17156193; 17285593; 17309748; 17322292; 17337451; 17403538; 17420470; 17435760; 17452051; 17521327; 17595233; 17613538; 17620097; 17907287; 17964870; 17970764; 18186648; 18397186; 18426885; 18521924; 18536738; 18573991; 18574154; 19043560; 19050632; 19074885; 19120480; 19122645; 19167431; 19247692; 19260860; 19264973; 19273470; 19327158; 19337385; 19401779; 19406482; 19423540; 19538217; 19570976; 19587002; 19660916; 19667203; 19723304; 19818630; 19843337; 19882212; 19898471; 19913121; 20002790; 20007577; 20039881; 20124104; 20300534; 20384614; 20389019; 20395963; 20403997; 20406964; 20438785; 20453000; 20470879; 20485444; 20519512; 20595247; 20628086; 20646321; 20713621; 20818820; 20844241; 20846183; 21042538; 21048031; 21097508; 21241317; 21263023; 21310790; 21330608; 21342182; 21677137; 21722177; 21739538; 21745515; 21757725; 21768114; 21864388; 21924184; 21978001; 21988832; 22062585; 22143988; 22218461; 22507623; 22563200; 22763410; 22795647; 22848741; 22870324; 22902391; 23062636; 23136938; 23182460; 23275338; 23300079; 23353647; 23382681; 23460743; 23711367; 23712977; 23740944; 23839082; 23888881; 23935490 nucleotide-binding oligomerization domain containing 1 Ensembl:ENSG00000106100 HGNC:16390 HPRD:05815 MIM:605980 Vega:OTTHUMG00000023923 NOD1 Bin Zhao, Yue Liu, Oliver He Gnb2-rs1 H12.3 HLC-7 PIG21 RACK1 WEB: http://www.ncbi.nlm.nih.gov/gene GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 10399 HLC7 5q35.3 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0001891 (EC: IDA); GO_0001934 (EC: IDA, PMID: 11312657); GO_0005080 (EC: IDA, PMID: 11279199); GO_0005102 (EC: NAS, PMID: 12809483); GO_0005515 (EC: IPI, PMID: 10849009); GO_0005634 (EC: IDA, PMID: 10849009); GO_0005737 (EC: IDA, PMID: 10849009); GO_0005739 (EC: IMP, PMID: 19767770); GO_0005829 (EC: IMP, PMID: 19767770); GO_0005856 (EC: IEA); GO_0006919 (EC: IMP, PMID: 19767770); GO_0007049 (EC: IEA); GO_0007369 (EC: IEA); GO_0008200 (EC: ISS); GO_0008656 (EC: IMP, PMID: 19767770); GO_0015935 (EC: ISS); GO_0016032 (EC: IEA); GO_0017148 (EC: ISS); GO_0019899 (EC: IPI); GO_0019903 (EC: IPI, PMID: 11278757); GO_0030178 (EC: ISS); GO_0030292 (EC: IDA, PMID: 9584165); GO_0030308 (EC: IDA, PMID: 9584165); GO_0030335 (EC: IDA); GO_0030425 (EC: ISS); GO_0030496 (EC: IDA, PMID: 15166316); GO_0030822 (EC: IMP); GO_0030971 (EC: IDA, PMID: 9584165); GO_0032436 (EC: IDA, PMID: 19785988); GO_0032464 (EC: IDA); GO_0032464 (EC: IMP, PMID: 19767770); GO_0032880 (EC: ISS); GO_0032947 (EC: TAS); GO_0042169 (EC: IDA, PMID: 11279199); GO_0043025 (EC: ISS); GO_0043065 (EC: IDA); GO_0043065 (EC: IMP, PMID: 19767770); GO_0043204 (EC: IEA); GO_0043547 (EC: IDA); GO_0044822 (EC: IDA); GO_0048471 (EC: IDA, PMID: 11279199); GO_0048511 (EC: IEA); GO_0050765 (EC: IMP); GO_0051302 (EC: ISS); GO_0051343 (EC: IMP); GO_0051726 (EC: IDA, PMID: 9584165); GO_0051898 (EC: IMP, PMID: 19767770); GO_0051901 (EC: IMP, PMID: 19767770); GO_0061099 (EC: IDA, PMID: 9584165); GO_0070062 (EC: IDA, PMID: 19056867); GO_0090003 (EC: IEA); GO_2000114 (EC: ISS); GO_2000543 (EC: ISS); GO_2001244 (EC: IMP, PMID: 19767770) PMID: 1326322; 1602151; 2499885; 7782277; 7821789; 8125298; 8290562; 8302854; 9442085; 9584165; 9765275; 9876970; 10329691; 10480917; 10490850; 10708423; 10820259; 10849009; 11046044; 11076863; 11256614; 11278757; 11279199; 11301323; 11312657; 11350068; 11516626; 11709417; 11733189; 11801604; 11824616; 11884618; 11934885; 11943848; 11956211; 11964397; 12193273; 12359736; 12388589; 12391233; 12400005; 12435334; 12477932; 12521306; 12524444; 12692135; 12761493; 12809483; 12884273; 12958311; 12960323; 14559993; 14654845; 14699138; 14702039; 14724252; 14963031; 14966116; 15159402; 15166316; 15202772; 15252133; 15254245; 15467455; 15489334; 15489336; 15548575; 15577927; 15592455; 15596539; 15611085; 15952740; 15955845; 16009940; 16061178; 16169070; 16189514; 16196087; 16212959; 16236267; 16381901; 16382134; 16449650; 16455055; 16689683; 16702786; 16705158; 16757810; 16849317; 16920332; 16997272; 17072338; 17108144; 17110338; 17166942; 17201176; 17244529; 17269730; 17361105; 17361185; 17409124; 17500595; 17515463; 17558393; 17574549; 17718421; 17875644; 17875659; 17900862; 17936896; 17965024; 18057008; 18088317; 18172692; 18420585; 18442364; 18557705; 18567578; 18596232; 18621736; 18624398; 18755685; 18781797; 18954305; 19000751; 19010305; 19056867; 19251694; 19372219; 19423701; 19451233; 19454010; 19616115; 19738201; 19767770; 19785988; 19855191; 19892429; 19917775; 19946739; 19966859; 20020495; 20020773; 20099848; 20103773; 20360068; 20410295; 20499158; 20529362; 20639865; 20689807; 20697360; 20736409; 20819076; 20858845; 20871634; 20874815; 20875397; 20976005; 21139048; 21145461; 21146485; 21212275; 21282530; 21319273; 21347310; 21525958; 21685945; 21738584; 21756811; 21848913; 21860413; 21890473; 21900206; 21906983; 21935400; 21963094; 21987572; 21988832; 22007921; 22053931; 22065575; 22069327; 22174317; 22174419; 22207523; 22240482; 22246531; 22262830; 22268729; 22289149; 22314363; 22334666; 22365833; 22378065; 22505724; 22538239; 22547057; 22558273; 22586326; 22592183; 22653060; 22659028; 22797925; 22863883; 22869111; 22903704; 22939629; 22990118; 23000965; 23077236; 23151878; 23173782; 23246001; 23313748; 23455324; 23455922; 23463506; 23608534; 23636454; 23651062; 23798571; 23893384; 23912224; 24005669; 24457600 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 Ensembl:ENSG00000204628 HGNC:4399 HPRD:01503 MIM:176981 Vega:OTTHUMG00000163380 GNB2L1 Bin Zhao, Yue Liu, Oliver He C19orf1 D19S1177E PER-EC1 PEREC1 TOM40 WEB: http://www.ncbi.nlm.nih.gov/gene TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 10452 19q13 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005739 (EC: IMP, Qualifier: NOT, PMID: 11745481); GO_0005742 (EC: IDA, PMID: 12198123); GO_0006626 (EC: IMP, PMID: 15644312); GO_0006626 (EC: TAS); GO_0006811 (EC: IEA); GO_0008320 (EC: ISS); GO_0008320 (EC: TAS, PMID: 15644312); GO_0015288 (EC: IEA); GO_0016021 (EC: IDA, PMID: 15644312); GO_0031307 (EC: ISS, PMID: 10980201); GO_0044267 (EC: TAS); GO_0046930 (EC: IEA); GO_0071806 (EC: ISS); GO_0071806 (EC: TAS, PMID: 15644312) PMID: 10520737; 10980201; 11745481; 12198123; 12477932; 15342556; 15489334; 15644312; 16495475; 17635912; 17672918; 18095154; 18430993; 18439552; 18823527; 19060910; 19060911; 19125160; 19197348; 19668339; 19734902; 19734903; 19913121; 20029386; 20061627; 20100581; 20370913; 20460622; 20467438; 20628086; 20877624; 20885792; 20932310; 21123754; 21139048; 21418511; 21627779; 21717124; 21720235; 21784354; 21803501; 21820212; 21825236; 21835183; 21890473; 21906983; 21909109; 21943158; 21963094; 21983493; 22005931; 22008263; 22054870; 22089642; 22190034; 22280891; 22359560; 22399527; 22472643; 22596268; 22694956; 22710912; 22832961; 22863908; 22898894; 22939629; 22939635; 23102119; 23182705; 23183136; 23207651; 23234877; 23288655; 23326517; 23419831; 23435269; 23522842; 23546992; 23562540; 23565137; 23626796; 23726366; 23844046; 24146538; 24149440 translocase of outer mitochondrial membrane 40 homolog (yeast) Ensembl:ENSG00000130204 HGNC:18001 HPRD:16274 MIM:608061 Vega:OTTHUMG00000180842 TOMM40 Bin Zhao, Yue Liu, Oliver He CIB CIBP KIP1 PRKDCIP SIP2-28 WEB: http://www.ncbi.nlm.nih.gov/gene CIB1 calcium and integrin binding 1 (calmyrin) 10519 15q25.3-q26 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0001525 (EC: IEA); GO_0001933 (EC: ISS); GO_0001934 (EC: ISS); GO_0001954 (EC: ISS); GO_0002931 (EC: ISS); GO_0005509 (EC: IMP, PMID: 15475008); GO_0005515 (EC: IPI, PMID: 10366599); GO_0005634 (EC: IDA); GO_0005654 (EC: IMP, PMID: 10366599); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA, PMID: 11756406); GO_0005737 (EC: IMP, PMID: 10366599); GO_0005783 (EC: IMP, PMID: 10366599); GO_0005794 (EC: IEA); GO_0005813 (EC: IDA); GO_0005886 (EC: IDA); GO_0006302 (EC: TAS, PMID: 9372844); GO_0006915 (EC: IMP, PMID: 10366599); GO_0006974 (EC: IDA, PMID: 12011095); GO_0007026 (EC: IDA); GO_0007113 (EC: IDA); GO_0007155 (EC: IEA); GO_0007286 (EC: ISS); GO_0008284 (EC: ISS); GO_0008285 (EC: IMP); GO_0010977 (EC: IDA); GO_0016020 (EC: IDA, PMID: 10366599); GO_0016324 (EC: IEA); GO_0017016 (EC: IPI, PMID: 11756406); GO_0030027 (EC: IDA); GO_0030220 (EC: ISS); GO_0030307 (EC: ISS); GO_0030335 (EC: ISS); GO_0030426 (EC: IDA); GO_0031122 (EC: IMP); GO_0032433 (EC: IDA); GO_0032587 (EC: IEA); GO_0033630 (EC: IDA, PMID: 11756406); GO_0038163 (EC: ISS); GO_0042127 (EC: IMP); GO_0042383 (EC: IDA); GO_0043005 (EC: IDA); GO_0043025 (EC: IDA); GO_0043066 (EC: IMP, PMID: 19854831); GO_0043495 (EC: IGI); GO_0044325 (EC: IEA); GO_0045653 (EC: ISS); GO_0048471 (EC: IDA, PMID: 11756406); GO_0048554 (EC: ISS); GO_0051092 (EC: IMP, PMID: 19854831); GO_0051301 (EC: IEA); GO_0051302 (EC: IMP); GO_0051898 (EC: ISS); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070374 (EC: ISS); GO_0070886 (EC: IDA); GO_0071356 (EC: IMP, PMID: 19854831); GO_0071363 (EC: ISS); GO_0071902 (EC: ISS); GO_0071944 (EC: IDA, PMID: 11756406); GO_0090004 (EC: IGI); GO_0090050 (EC: ISS); GO_0090314 (EC: IMP, PMID: 19854831); GO_0097191 (EC: TAS, PMID: 19805025); GO_1900026 (EC: IDA, PMID: 11756406); GO_1901313 (EC: ISS); GO_1990090 (EC: IDA); GO_2000256 (EC: ISS) PMID: 9030514; 9372844; 9852683; 10366599; 10523297; 10822252; 10826701; 11039900; 11756406; 11856312; 11997098; 12011095; 12023286; 12477932; 12651910; 12714504; 12881299; 14992593; 15190070; 15203218; 15231747; 15475008; 15489334; 15574431; 15604093; 15685448; 15885068; 15933764; 16061695; 16418530; 16582881; 16723353; 16825200; 17516631; 18627437; 18989529; 19056867; 19388079; 19805025; 19854831; 19913121; 19923078; 20473878; 20628086; 20951827; 20959453; 21215777; 21388953; 21748785; 21857112; 21890473; 21906983; 21963094; 21988832; 22505724; 22547769; 22779914; 22964641; 23503467; 24011356; 24250222 calcium and integrin binding 1 (calmyrin) HGNC:16920 HPRD:03800 MIM:602293 CIB1 Bin Zhao, Yue Liu, Oliver He ESA1 HTATIP HTATIP1 PLIP TIP TIP60 ZC2HC5 cPLA2 WEB: http://www.ncbi.nlm.nih.gov/gene KAT5 K(lysine) acetyltransferase 5 10524 11q13 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0000122 (EC: IMP, PMID: 17360565); GO_0000812 (EC: IDA); GO_0003713 (EC: IDA, PMID: 14966270); GO_0003713 (EC: TAS, PMID: 17360565); GO_0004402 (EC: IDA, PMID: 18397884); GO_0004402 (EC: IDA, Qualifier: contributes_to, PMID: 14966270); GO_0004402 (EC: IMP, PMID: 17996965); GO_0005515 (EC: IPI, PMID: 15383276); GO_0005634 (EC: IDA); GO_0005654 (EC: TAS); GO_0005667 (EC: IEA); GO_0005730 (EC: IDA, PMID: 16387653); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005829 (EC: IEA); GO_0006302 (EC: IMP, PMID: 10966108); GO_0006325 (EC: TAS); GO_0006351 (EC: IEA); GO_0006978 (EC: IDA, PMID: 14966270); GO_0010212 (EC: IDA, PMID: 18397884); GO_0016032 (EC: IEA); GO_0016573 (EC: IDA, PMID: 10966108); GO_0030521 (EC: NAS, PMID: 15572661); GO_0032403 (EC: IEA); GO_0032703 (EC: IDA, PMID: 17360565); GO_0032777 (EC: IDA, PMID: 14966270); GO_0035267 (EC: IDA, PMID: 10966108); GO_0040008 (EC: IEA); GO_0043161 (EC: IMP, PMID: 18397884); GO_0045892 (EC: IDA, PMID: 17360565); GO_0045893 (EC: IDA, PMID: 14966270); GO_0045893 (EC: NAS, PMID: 15572661); GO_0045944 (EC: IEA); GO_0046872 (EC: IEA); GO_0048471 (EC: IEA); GO_0050681 (EC: NAS, PMID: 15572661); GO_0070491 (EC: IPI, PMID: 17360565) PMID: 8125298; 8607265; 8889548; 9388189; 10096020; 10362352; 10364196; 10393559; 10486269; 10720489; 10966108; 11111051; 11262386; 11275565; 11416127; 11441186; 11509179; 11591700; 11839798; 11927554; 11994312; 12032152; 12036595; 12150997; 12154097; 12464179; 12468530; 12477932; 12551922; 12737628; 12776177; 12801643; 12888553; 12963728; 14699153; 14701804; 14966270; 15005629; 15016909; 15017382; 15042092; 15044485; 15121871; 15196461; 15310756; 15331662; 15383276; 15474031; 15489334; 15502158; 15572661; 15572685; 15591049; 15647280; 15829968; 15985650; 16001085; 16141325; 16169070; 16189514; 16223726; 16287840; 16341205; 16344560; 16387653; 16455055; 16469706; 16501607; 16601686; 16603769; 16698308; 16705183; 16835243; 16844118; 17110330; 17126496; 17189186; 17308053; 17360565; 17368826; 17406968; 17418098; 17551969; 17573780; 17636029; 17704809; 17709392; 17728759; 17827213; 17851107; 17967892; 17980166; 17996965; 18003922; 18029348; 18087039; 18096664; 18218781; 18239623; 18263878; 18264029; 18280244; 18285460; 18397884; 18406329; 18414493; 18451177; 18458078; 18485870; 18499675; 18577246; 18625847; 18985155; 19048121; 19114310; 19150978; 19169279; 19176879; 19308289; 19716452; 19783983; 19800870; 19819149; 19846935; 19895790; 19909775; 19938016; 20070254; 20100829; 20159953; 20224553; 20332121; 20351180; 20383146; 20507282; 20542002; 20796290; 20946988; 21045206; 21157427; 21273583; 21320689; 21320693; 21463657; 21574959; 21658600; 21668587; 21699783; 21704408; 21781306; 21832049; 21900206; 21906983; 21936881; 21963094; 21988832; 22018239; 22071692; 22081016; 22084066; 22094252; 22100137; 22110127; 22159227; 22249179; 22354990; 22379092; 22391203; 22398289; 22467210; 22539723; 22573825; 22586264; 22673729; 22902274; 22939624; 22939629; 23044042; 23046361; 23056207; 23178490; 23238566; 23297341; 23555077; 23576563; 23609452; 23677994; 23685072; 23708966; 23775119; 23777805; 23857583 K(lysine) acetyltransferase 5 Ensembl:ENSG00000172977 HGNC:5275 HPRD:03245 MIM:601409 Vega:OTTHUMG00000166617 KAT5 Bin Zhao, Yue Liu, Oliver He APG7-LIKE APG7L GSA7 WEB: http://www.ncbi.nlm.nih.gov/gene ATG7 autophagy related 7 10533 3p25.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000407 (EC: IEA); GO_0001889 (EC: IEA); GO_0004839 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11096062); GO_0005737 (EC: TAS, PMID: 10233149); GO_0005930 (EC: ISS); GO_0006464 (EC: TAS, PMID: 10233149); GO_0006497 (EC: IDA, PMID: 12890687); GO_0006520 (EC: IEA); GO_0006914 (EC: IEA); GO_0006996 (EC: IEA); GO_0007628 (EC: IEA); GO_0009791 (EC: IEA); GO_0015031 (EC: IEA); GO_0016239 (EC: IMP); GO_0019778 (EC: ISS); GO_0021680 (EC: IEA); GO_0021860 (EC: IEA); GO_0021955 (EC: IEA); GO_0021987 (EC: IEA); GO_0030163 (EC: IEA); GO_0031396 (EC: IEA); GO_0031401 (EC: IDA, PMID: 12890687); GO_0032446 (EC: IEA); GO_0042594 (EC: IEA); GO_0042803 (EC: IDA, PMID: 11096062); GO_0043066 (EC: IEA); GO_0050877 (EC: IEA); GO_0055013 (EC: IEA); GO_0061025 (EC: TAS, PMID: 10233149) PMID: 10233149; 11096062; 11825910; 11890701; 12477932; 12482611; 12890687; 15342556; 15489334; 16303743; 16303767; 16344560; 16704426; 18029348; 18187620; 18296641; 18688877; 19124466; 19148225; 19635843; 19881538; 20083906; 20195357; 20379614; 20543840; 20562859; 20697744; 21139048; 21274862; 21655094; 21832049; 21903422; 21963094; 22170151; 22499945; 22622204; 22674379; 22863883; 22927446; 23295909; 23386620; 23527187; 23640897; 23824909; 23894380; 24068947; 24250222 autophagy related 7 Ensembl:ENSG00000197548 HGNC:16935 HPRD:12293 MIM:608760 Vega:OTTHUMG00000129740 ATG7 Bin Zhao, Yue Liu, Oliver He MTAP44 TLDC5 p44 WEB: http://www.ncbi.nlm.nih.gov/gene IFI44 interferon-induced protein 44 10561 1p31.1 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0005737 (EC: IEA); GO_0009615 (EC: TAS, PMID: 7925411) PMID: 7925411; 12477932; 12539042; 15489334; 16886895; 17207965; 17784819; 18029348; 18953482; 19460752; 20237496; 21963094; 21987572; 22896602; 23453885 interferon-induced protein 44 Ensembl:ENSG00000137965 HGNC:16938 HPRD:09998 MIM:610468 Vega:OTTHUMG00000009723 IFI44 Bin Zhao, Yue Liu, Oliver He HUMPMKI PMK PMKA PMKASE WEB: http://www.ncbi.nlm.nih.gov/gene PMVK phosphomevalonate kinase 10654 RP11-307C12.5 1q22 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0004631 (EC: IDA, PMID: 14680974); GO_0005524 (EC: IDA, PMID: 16519518); GO_0005777 (EC: IDA, PMID: 10191291); GO_0005829 (EC: IDA, PMID: 14729858); GO_0005829 (EC: TAS); GO_0006695 (EC: IDA, PMID: 8663599); GO_0006695 (EC: TAS); GO_0016126 (EC: IDA, PMID: 16519518); GO_0019287 (EC: IEA); GO_0044281 (EC: TAS); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070723 (EC: IEP, PMID: 10191291) PMID: 8188698; 8663599; 10191291; 12477932; 14680974; 14729858; 15489334; 16519518; 17180682; 17353931; 17902708; 18618710; 18660489; 18798562; 19056867; 19913121; 20628086; 21139048; 21890473; 21906983; 22544366; 22939629; 23000965; 23535732 phosphomevalonate kinase Ensembl:ENSG00000163344 HGNC:9141 HPRD:07404 MIM:607622 Vega:OTTHUMG00000037415 PMVK Bin Zhao, Yue Liu, Oliver He BRUNOL2 CUG-BP CUGBP CUGBP1 EDEN-BP NAB50 NAPOR hNab50 WEB: http://www.ncbi.nlm.nih.gov/gene CELF1 CUGBP, Elav-like family member 1 10658 11p11 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0000166 (EC: IEA); GO_0000900 (EC: NAS, PMID: 10893231); GO_0003723 (EC: IDA, PMID: 16946708); GO_0003729 (EC: IDA, PMID: 14726956); GO_0005515 (EC: IPI, PMID: 16946708); GO_0005634 (EC: IDA); GO_0005634 (EC: NAS, PMID: 10893231); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IEA); GO_0006376 (EC: ISS); GO_0006397 (EC: TAS, PMID: 8948631); GO_0007281 (EC: NAS, PMID: 10893231); GO_0007286 (EC: IEA); GO_0009790 (EC: NAS, PMID: 10893231); GO_0016246 (EC: NAS, PMID: 10893231); GO_0017148 (EC: NAS, PMID: 10893231); GO_0030529 (EC: NAS, PMID: 10893231); GO_0031369 (EC: IEA); GO_0040018 (EC: IEA); GO_0042835 (EC: IDA, PMID: 10893231); GO_0043484 (EC: IDA, PMID: 16946708); GO_0044822 (EC: IDA) PMID: 8789448; 8912635; 8948631; 9371827; 10446244; 10536163; 10893231; 11124939; 11158314; 11564876; 11686919; 12477932; 12799066; 14657503; 14702039; 14726956; 14759258; 15082764; 15099703; 15489334; 15546872; 15756469; 16169070; 16341674; 16344560; 16601207; 16946708; 17531403; 17854664; 17936705; 18039683; 18164289; 18243120; 18570922; 19047369; 19106619; 19322201; 19471022; 19553194; 19615732; 20020773; 20051426; 20227387; 20547756; 20603324; 20935630; 20947024; 21139048; 21508681; 21637851; 21832049; 21890473; 21906983; 21963094; 22053931; 22117072; 22355723; 22365833; 22505724; 22646166; 22982313; 23000965; 23155001; 23324604; 24457600 CUGBP, Elav-like family member 1 Ensembl:ENSG00000149187 HGNC:2549 HPRD:03046 MIM:601074 CELF1 Bin Zhao, Yue Liu, Oliver He HRG3 pro-NRG3 WEB: http://www.ncbi.nlm.nih.gov/gene NRG3 neuregulin 3 10718 10q22-q23 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0001558 (EC: NAS, PMID: 9275162); GO_0005576 (EC: NAS, PMID: 9275162); GO_0005887 (EC: NAS, PMID: 9275162); GO_0007171 (EC: NAS, PMID: 9275162); GO_0007389 (EC: IEA); GO_0008083 (EC: NAS, PMID: 9275162); GO_0030297 (EC: NAS, PMID: 9275162); GO_0030971 (EC: NAS, PMID: 9275162); GO_0060596 (EC: IEA) PMID: 9275162; 11032326; 12477932; 14702039; 15164054; 16344560; 16478787; 17598910; 17880691; 17962208; 18519826; 18521091; 18708184; 18846501; 19086053; 19118813; 19776380; 19913121; 20379614; 20398908; 20548296; 20628086; 20713722; 21248748; 21348951; 21705454; 21762460; 22589734; 22831755; 22981155; 23251661; 23315268; 23382691; 23393555; 24431462 neuregulin 3 Ensembl:ENSG00000185737 HGNC:7999 HPRD:16115 MIM:605533 Vega:OTTHUMG00000018626 NRG3 Bin Zhao, Yue Liu, Oliver He CC-CKR-9 CDw199 GPR-9-6 GPR28 WEB: http://www.ncbi.nlm.nih.gov/gene CCR9 chemokine (C-C motif) receptor 9 10803 3p21.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0004950 (EC: TAS, PMID: 10229797); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 10229797); GO_0006935 (EC: IEA); GO_0006955 (EC: IEA); GO_0006968 (EC: TAS, PMID: 10544196); GO_0007186 (EC: TAS, PMID: 10544196); GO_0007204 (EC: TAS, PMID: 10229797); GO_0016493 (EC: IEA); GO_0070098 (EC: TAS, PMID: 10229797) PMID: 2834384; 10229797; 10498628; 10544196; 10602049; 10640743; 10702689; 10974041; 11046037; 12477932; 12816994; 14559839; 15489334; 15623660; 15717282; 16344560; 17205512; 17570212; 18240029; 18245518; 18245522; 18577758; 19423540; 19525985; 19756884; 20036838; 20056178; 20081876; 20190752; 20406964; 20438785; 20738854; 20947433; 21075690; 21344163; 21511186; 21637913; 21984373; 23326330 chemokine (C-C motif) receptor 9 Ensembl:ENSG00000173585 HGNC:1610 HPRD:09200 MIM:604738 Vega:OTTHUMG00000133450 CCR9 Bin Zhao, Yue Liu, Oliver He KIND2 MIG2 PLEKHC1 UNC112 UNC112B mig-2 WEB: http://www.ncbi.nlm.nih.gov/gene FERMT2 fermitin family member 2 10979 14q22.1 20140408 9606 14 protein-coding Official from a nomenclature committee GO_0001725 (EC: IEA); GO_0005515 (EC: IPI); GO_0005547 (EC: IDA); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0005925 (EC: IDA); GO_0005938 (EC: IEA); GO_0007160 (EC: IMP); GO_0007160 (EC: ISS); GO_0007179 (EC: IMP); GO_0007229 (EC: IMP); GO_0008360 (EC: IEA); GO_0009986 (EC: IEA); GO_0016055 (EC: IMP); GO_0031234 (EC: IDA); GO_0031258 (EC: IEA); GO_0031674 (EC: IEA); GO_0031941 (EC: IEA); GO_0033622 (EC: IMP); GO_0034329 (EC: TAS); GO_0034446 (EC: ISS); GO_0048041 (EC: ISS); GO_0072657 (EC: ISS) PMID: 8175911; 12477932; 12508121; 12679033; 12697302; 12789646; 14702039; 14745725; 15489334; 17081983; 18029348; 18458155; 18528435; 18781797; 19854292; 20127858; 20702409; 20861856; 21139048; 21325030; 21356350; 21624607; 21636915; 21832049; 21890473; 21922223; 22030399; 22056622; 22078565; 22391155; 22648415; 22699938; 22863883; 22939629; 23000965; 23151599; 23209705; 23211537; 23337877; 23383273; 23483548; 23508013; 23535732; 23667531; 23723426; 23857544 fermitin family member 2 Ensembl:ENSG00000073712 HGNC:15767 HPRD:06374 MIM:607746 Vega:OTTHUMG00000140309 FERMT2 Bin Zhao, Yue Liu, Oliver He ASFGF2 FGF-AS FGF2AS GFG-1 GFG1 WEB: http://www.ncbi.nlm.nih.gov/gene NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 11162 4q26 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0005575 (EC: ND); GO_0005634 (EC: IEA); GO_0005739 (EC: IEA); GO_0008083 (EC: TAS, PMID: 7984147); GO_0008150 (EC: ND); GO_0016787 (EC: IEA) PMID: 7984147; 7999082; 9406864; 10022609; 11266510; 11801566; 12477932; 15247275; 15489334; 16712791; 17203973; 17569023; 17681892; 18401527; 19054571; 19416273; 19423540; 19913121; 20406964; 20438785; 20628086; 20800603; 21139048; 21890473 nudix (nucleoside diphosphate linked moiety X)-type motif 6 Ensembl:ENSG00000170917 HGNC:8053 HPRD:05880 MIM:606261 Vega:OTTHUMG00000039507 NUDT6 Bin Zhao, Yue Liu, Oliver He WIF-1 WEB: http://www.ncbi.nlm.nih.gov/gene WIF1 WNT inhibitory factor 1 11197 UNQ191/PRO217 12q14.3 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 19188438); GO_0005576 (EC: IEA); GO_0007165 (EC: NAS, PMID: 10201374); GO_0007275 (EC: IEA); GO_0016055 (EC: IEA); GO_0045600 (EC: IEA) PMID: 10201374; 12477932; 12975309; 15351726; 15377999; 15389810; 15489334; 15735743; 16007117; 16427602; 16428476; 16476441; 16516163; 16525492; 16609023; 17012225; 17094650; 17171686; 17384664; 18005197; 18079202; 18093228; 18256869; 18701434; 19054571; 19085002; 19174556; 19188438; 19307728; 19453261; 19496188; 19528461; 19570204; 19690140; 19773381; 19787276; 19885602; 19887605; 19926868; 20066439; 20119713; 20197388; 20334650; 20364027; 20376066; 20395289; 20421722; 20573255; 20596629; 20697356; 20811686; 20844743; 20874008; 21052890; 21642372; 21743455; 21819494; 21873353; 21928342; 21988832; 22002305; 22315090; 22333550; 22504421; 22901505; 22951645; 22951732; 22986341; 23193918; 23316316; 23328978; 23358094; 23417837; 23686431; 23746174; 23939044; 24118380; 24289328 WNT inhibitory factor 1 Ensembl:ENSG00000156076 HGNC:18081 HPRD:05541 MIM:605186 Vega:OTTHUMG00000168832 WIF1 Bin Zhao, Yue Liu, Oliver He CARD7 CIDED CLR17.1 DEFCAP DEFCAP-L/S NAC NALP1 PP1044 SLEV1 VAMAS1 WEB: http://www.ncbi.nlm.nih.gov/gene NLRP1 NLR family, pyrin domain containing 1 22861 17p13.2 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 11472070); GO_0005524 (EC: IDA, PMID: 15212762); GO_0005622 (EC: IC, PMID: 11076957); GO_0005634 (EC: IDA, PMID: 17164409); GO_0005829 (EC: TAS); GO_0006915 (EC: NAS, PMID: 11076957); GO_0006919 (EC: IDA, PMID: 15212762); GO_0006919 (EC: NAS, PMID: 11076957); GO_0008656 (EC: NAS, PMID: 11076957); GO_0019899 (EC: IPI, PMID: 11076957); GO_0019904 (EC: IPI, PMID: 16575408); GO_0032495 (EC: ISS); GO_0035872 (EC: TAS); GO_0042742 (EC: ISS); GO_0045087 (EC: TAS); GO_0050718 (EC: ISS); GO_0050727 (EC: IC, PMID: 15212762); GO_0051402 (EC: IDA, PMID: 15212762); GO_0072558 (EC: IDA, PMID: 12191486); GO_0072558 (EC: TAS) PMID: 8619474; 8781126; 9110174; 10231032; 11076957; 11113115; 11250163; 11270363; 11472070; 11592035; 12191486; 12477932; 12563287; 14527388; 14691733; 14702039; 15107016; 15174051; 15212762; 15749123; 16575408; 17164409; 17377159; 17418785; 17620097; 17637824; 18263805; 18348116; 18854154; 18946481; 19001869; 19074885; 19120479; 19223160; 19337385; 19727120; 19913121; 20152874; 20370570; 20379614; 20403135; 20502346; 20574744; 20628086; 20697295; 20800603; 21098108; 21149496; 21245836; 21252346; 21331694; 21376416; 21946017; 21976003; 22087307; 22117610; 22227487; 22235789; 22507623; 22524199; 22665479; 23053059; 23253924; 23349227; 23374100; 23380025; 23382179; 23508996; 23563199; 23940760; 24008734 NLR family, pyrin domain containing 1 Ensembl:ENSG00000091592 HGNC:14374 HPRD:07364 MIM:606636 Vega:OTTHUMG00000132419 NLRP1 Bin Zhao, Yue Liu, Oliver He C1QR1 C1qR(P) C1qRP CDw93 ECSM3 MXRA4 dJ737E23.1 WEB: http://www.ncbi.nlm.nih.gov/gene CD93 CD93 molecule 22918 20p11.21 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0001849 (EC: IDA, PMID: 11781389); GO_0004872 (EC: NAS, PMID: 9047234); GO_0005509 (EC: IEA); GO_0005515 (EC: IPI, PMID: 15459234); GO_0005886 (EC: IDA); GO_0006909 (EC: NAS, PMID: 10092817); GO_0009986 (EC: IEA); GO_0016021 (EC: IC, PMID: 9047234); GO_0016023 (EC: IEA); GO_0016032 (EC: IEA); GO_0016337 (EC: IDA, PMID: 11994479); GO_0030246 (EC: IEA); GO_0042116 (EC: NAS, PMID: 9047234) PMID: 1377218; 2212670; 8062452; 8710908; 9047234; 9136074; 9469455; 9476117; 9777410; 10092817; 10430665; 10648005; 11076863; 11086025; 11204562; 11256614; 11780052; 11781389; 11994479; 12140365; 12213329; 12477932; 12891708; 14702039; 15459234; 15489334; 15489336; 15819698; 16381901; 17474147; 18094537; 18599554; 18834607; 19166692; 19344414; 19372141; 19423540; 19796797; 20237496; 20406964; 20438785; 20512406; 21332844; 21768350; 21988832; 22206251; 23251661; 23268996; 23272129; 23651874; 24124411 CD93 molecule Ensembl:ENSG00000125810 HGNC:15855 HPRD:00396 MIM:120577 Vega:OTTHUMG00000032058 CD93 Bin Zhao, Yue Liu, Oliver He CBS-1 CBS1 MSRB PILB WEB: http://www.ncbi.nlm.nih.gov/gene MSRB2 methionine sulfoxide reductase B2 22921 CGI-131 10p12 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0003700 (EC: TAS, PMID: 10375640); GO_0003779 (EC: ISS); GO_0005739 (EC: ISS, PMID: 14699060); GO_0006355 (EC: TAS, PMID: 10375640); GO_0006979 (EC: IEA); GO_0008270 (EC: ISS, PMID: 14699060); GO_0030041 (EC: ISS); GO_0030091 (EC: ISS, PMID: 14699060); GO_0033743 (EC: ISS) PMID: 8749308; 10375640; 10810093; 12220640; 12477932; 14699060; 14759519; 14980072; 16385451; 16480945; 17601350; 17943184; 18424444; 18977241; 19237503; 19322201; 19542914; 20877624; 22145905; 22634633; 22939629; 23251661 methionine sulfoxide reductase B2 Ensembl:ENSG00000148450 HGNC:17061 HPRD:17606 MIM:613782 Vega:OTTHUMG00000017812 MSRB2 Bin Zhao, Yue Liu, Oliver He ATF6A WEB: http://www.ncbi.nlm.nih.gov/gene ATF6 activating transcription factor 6 22926 1q22-q23 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000139 (EC: TAS); GO_0003700 (EC: IEA); GO_0003713 (EC: TAS, PMID: 10866666); GO_0005515 (EC: IPI, PMID: 16469704); GO_0005634 (EC: TAS, PMID: 10564271); GO_0005635 (EC: TAS, PMID: 10866666); GO_0005654 (EC: TAS); GO_0005789 (EC: TAS); GO_0006351 (EC: IEA); GO_0006357 (EC: TAS, PMID: 10564271); GO_0006457 (EC: TAS, PMID: 10564271); GO_0006950 (EC: TAS, PMID: 10866666); GO_0006987 (EC: TAS); GO_0006990 (EC: TAS, PMID: 9837962); GO_0007165 (EC: TAS, PMID: 9271374); GO_0016021 (EC: IEA); GO_0030968 (EC: TAS, PMID: 19816510); GO_0043565 (EC: IEA); GO_0044267 (EC: TAS) PMID: 2516827; 8889548; 9271374; 9837962; 10564271; 10866666; 11158310; 11163209; 11256944; 11287625; 11483355; 11805088; 11821395; 11909875; 12014989; 12076252; 12097557; 12477932; 12713871; 12782636; 12805554; 12949534; 14699159; 14765107; 15063770; 15299016; 15342556; 15489334; 15598891; 15899857; 16196087; 16469704; 16505252; 16710414; 17092596; 17101776; 17327457; 17440018; 17442311; 17522056; 17686766; 18022401; 18635891; 18650380; 18840095; 19122331; 19304306; 19420237; 19667116; 19693772; 19722195; 19723703; 19772629; 19816510; 19822759; 19913121; 20160352; 20219975; 20628086; 20732420; 20800603; 20936779; 21106748; 21131360; 21150130; 21211013; 21329801; 21329806; 21345978; 21355074; 21385877; 21454619; 21521793; 21693764; 21809331; 21832049; 21841196; 21906983; 21963094; 21988832; 22013072; 22102412; 22146569; 22268729; 22354938; 22577136; 22872700; 22917505; 22956602; 23011799; 23037953; 23382691; 23661758; 23864652; 23924739; 24043630 activating transcription factor 6 Ensembl:ENSG00000118217 HGNC:791 HPRD:16118 MIM:605537 Vega:OTTHUMG00000023961 ATF6 Bin Zhao, Yue Liu, Oliver He SIR2 SIR2L SIR2L2 WEB: http://www.ncbi.nlm.nih.gov/gene SIRT2 sirtuin 2 22933 19q13 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000183 (EC: NAS, PMID: 11427894); GO_0003950 (EC: TAS, Qualifier: NOT, PMID: 17456799); GO_0005515 (EC: IPI, PMID: 12697818); GO_0005677 (EC: NAS, PMID: 12697818); GO_0005737 (EC: IDA, PMID: 12697818); GO_0005874 (EC: IDA, PMID: 12620231); GO_0006342 (EC: NAS, PMID: 12697818); GO_0006348 (EC: NAS, PMID: 11427894); GO_0006471 (EC: NAS, PMID: 10381378); GO_0006471 (EC: TAS, Qualifier: NOT, PMID: 17456799); GO_0006476 (EC: IDA, PMID: 17172643); GO_0007067 (EC: IEA); GO_0007096 (EC: NAS, PMID: 12697818); GO_0008134 (EC: IPI, PMID: 12887892); GO_0008270 (EC: IDA, PMID: 11427894); GO_0016458 (EC: NAS, PMID: 10381378); GO_0016575 (EC: TAS, PMID: 12697818); GO_0017136 (EC: IDA, PMID: 11427894); GO_0021762 (EC: IEP); GO_0033558 (EC: IDA, PMID: 17172643); GO_0034979 (EC: IDA); GO_0034983 (EC: IDA); GO_0035035 (EC: IPI, PMID: 12887892); GO_0042325 (EC: NAS, PMID: 12697818); GO_0042826 (EC: IPI, PMID: 12620231); GO_0042903 (EC: IDA, PMID: 12620231); GO_0043130 (EC: IDA, PMID: 12697818); GO_0043161 (EC: IMP); GO_0045843 (EC: IDA, PMID: 12887892); GO_0045892 (EC: IDA, PMID: 12887892); GO_0051775 (EC: NAS, PMID: 12887892); GO_0070403 (EC: IDA, PMID: 11427894) PMID: 8125298; 8619474; 9110174; 10381378; 10393250; 10873683; 10931946; 11427894; 11483616; 11812793; 12477932; 12620231; 12697818; 12887892; 12963026; 14522900; 14702039; 15126506; 15213244; 15220471; 15274642; 15328540; 15489334; 15719057; 16079181; 16211212; 16247014; 16344560; 16565078; 16648462; 16909107; 17172643; 17353931; 17456799; 17516032; 17708669; 17726514; 18193082; 18249170; 18249187; 18332217; 18722353; 18995842; 19282667; 19801601; 20159555; 20237298; 20378838; 20543840; 20562129; 20849899; 21349544; 21511279; 21726808; 21890473; 22014574; 22053931; 22089141; 22166219; 22302938; 22651940; 22735931; 22796962; 22819792; 22833565; 22857867; 22944623; 23000965; 23175188; 23348706; 23358244; 23382805; 23416275; 23460888; 23468428; 23475622; 23723075; 23806683; 23908241; 24161395; 24183459 sirtuin 2 Ensembl:ENSG00000068903 HGNC:10886 HPRD:10377 MIM:604480 Vega:OTTHUMG00000150480 SIRT2 Bin Zhao, Yue Liu, Oliver He DKK-1 SK WEB: http://www.ncbi.nlm.nih.gov/gene DKK1 dickkopf WNT signaling pathway inhibitor 1 22943 UNQ492/PRO1008 10q11.2 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0000122 (EC: IDA); GO_0000122 (EC: ISS); GO_0000904 (EC: IEA); GO_0001706 (EC: IEA); GO_0001707 (EC: IEA); GO_0001942 (EC: IEA); GO_0002090 (EC: IDA, PMID: 17804805); GO_0004871 (EC: TAS, PMID: 10383463); GO_0005515 (EC: IPI, PMID: 11448771); GO_0005615 (EC: IDA, PMID: 11448771); GO_0005886 (EC: IDA, PMID: 16263759); GO_0008083 (EC: TAS, PMID: 10383463); GO_0030326 (EC: IEA); GO_0030514 (EC: IEA); GO_0030900 (EC: IEA); GO_0031333 (EC: IDA, PMID: 11448771); GO_0032526 (EC: IEA); GO_0033137 (EC: IDA); GO_0042662 (EC: IDA); GO_0042663 (EC: IDA); GO_0048019 (EC: IDA); GO_0048642 (EC: IEA); GO_0050750 (EC: IDA, PMID: 16263759); GO_0060325 (EC: IEA); GO_0060394 (EC: IDA); GO_0090082 (EC: ISS); GO_0090090 (EC: IDA, PMID: 11448771); GO_0090090 (EC: IGI, PMID: 18166153); GO_0090244 (EC: IEA); GO_1900116 (EC: IDA); GO_1901296 (EC: IDA); GO_2000726 (EC: IDA) PMID: 10383463; 10570958; 10965128; 11357136; 11448771; 11516963; 11742004; 11840333; 12050670; 12167704; 12477932; 12740383; 12975309; 14695408; 15035989; 15117970; 15229249; 15231748; 15340161; 15378020; 15451431; 15489334; 15542433; 15592430; 15592505; 15694380; 15923613; 16189514; 16263759; 16293576; 16491118; 16568085; 16646053; 16763196; 16863544; 16919965; 17026960; 17068150; 17159916; 17237793; 17245340; 17255354; 17329407; 17353931; 17373700; 17449905; 17485441; 17643814; 17657240; 17700537; 17702698; 17804805; 17876334; 17984176; 17987039; 18044981; 18157634; 18163421; 18166153; 18294945; 18297060; 18305214; 18331598; 18339843; 18461655; 18502762; 18505732; 18521528; 18546262; 18561248; 18571836; 18606139; 18653765; 18843784; 18978943; 19016584; 19040566; 19060904; 19067746; 19093005; 19247449; 19252761; 19273195; 19303159; 19358268; 19389391; 19396460; 19407319; 19424619; 19453261; 19477926; 19540374; 19657367; 19675559; 19711349; 19720407; 19744316; 19746449; 19776352; 19787627; 19820386; 19832854; 19895917; 19898734; 19926868; 19936252; 19943155; 19955106; 19995224; 20004015; 20019092; 20033851; 20038269; 20039407; 20062063; 20093360; 20101398; 20139903; 20153141; 20543981; 20549706; 20589421; 20603237; 20613589; 20618428; 20628624; 20634891; 20650998; 20653953; 20797317; 20819596; 20823417; 20843343; 20847303; 20920327; 20929859; 20932948; 20957670; 21029453; 21034532; 21062498; 21076409; 21098705; 21164019; 21304055; 21317455; 21344486; 21362762; 21389688; 21531794; 21540552; 21546446; 21562161; 21607803; 21617850; 21663914; 21683813; 21712726; 21805521; 21811562; 21833531; 21858178; 21909757; 21935273; 21944272; 21944579; 21955977; 21984209; 21988832; 22000856; 22015605; 22022386; 22032557; 22042700; 22048647; 22120987; 22122879; 22278426; 22321022; 22358062; 22363428; 22386696; 22391424; 22399772; 22430125; 22447857; 22455953; 22496615; 22527202; 22576962; 22589387; 22592030; 22649545; 22723594; 22738799; 22789636; 22796372; 22815877; 22898215; 22966878; 22984994; 23028464; 23041840; 23125289; 23152495; 23261982; 23266194; 23316316; 23348703; 23359112; 23360788; 23396252; 23445914; 23452984; 23457386; 23467116; 23595579; 23600832; 23636253; 23702386; 23922913; 24024966; 24361889 dickkopf WNT signaling pathway inhibitor 1 Ensembl:ENSG00000107984 HGNC:2891 HPRD:05544 MIM:605189 Vega:OTTHUMG00000018247 DKK1 Bin Zhao, Yue Liu, Oliver He Munc13-1 WEB: http://www.ncbi.nlm.nih.gov/gene UNC13A unc-13 homolog A (C. elegans) 23025 19p13.11 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0001956 (EC: IEA); GO_0005737 (EC: IEA); GO_0007528 (EC: IEA); GO_0016081 (EC: IEA); GO_0016188 (EC: IEA); GO_0019992 (EC: IEA); GO_0030054 (EC: IEA); GO_0031594 (EC: IEA); GO_0035249 (EC: IEA); GO_0035556 (EC: IEA); GO_0042734 (EC: IEA); GO_0046872 (EC: IEA); GO_0048172 (EC: IEA); GO_0050435 (EC: IEA); GO_0060384 (EC: IEA) PMID: 10470851; 12421765; 12477932; 12871971; 14702039; 14734538; 15123597; 16344560; 19734901; 19996097; 20379614; 20385924; 22118904; 22248876; 22921269; 22959728; 23251661; 23801330; 24250222 unc-13 homolog A (C. elegans) Ensembl:ENSG00000130477 HGNC:23150 MIM:609894 Vega:OTTHUMG00000163877 UNC13A Bin Zhao, Yue Liu, Oliver He HBEBP3 HBEBP36 KIBRA MEMRYQTL WEB: http://www.ncbi.nlm.nih.gov/gene WWC1 WW and C2 domain containing 1 23286 5q34 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0003713 (EC: IDA, PMID: 16684779); GO_0005515 (EC: IPI, PMID: 16684779); GO_0005634 (EC: IDA, PMID: 16684779); GO_0005737 (EC: IDA, PMID: 16684779); GO_0005829 (EC: TAS); GO_0006351 (EC: IEA); GO_0006355 (EC: IEA); GO_0016477 (EC: IDA, PMID: 18596123); GO_0030674 (EC: IEA); GO_0032587 (EC: IDA, PMID: 18190796); GO_0035329 (EC: TAS); GO_0035330 (EC: IMP); GO_0043234 (EC: IEA); GO_0043410 (EC: IDA, PMID: 18190796); GO_0048471 (EC: IDA, PMID: 18596123) PMID: 8889548; 10048485; 12477932; 12559952; 14702039; 15081397; 15489334; 16169070; 16484223; 16684779; 17010949; 17043677; 17053149; 17353070; 17707552; 17994011; 18029348; 18190796; 18194457; 18205171; 18378080; 18596123; 18672031; 18789830; 19058786; 19397951; 19606085; 19804789; 20125193; 20150879; 20185150; 20379614; 20509760; 20691427; 20881395; 21173572; 21185624; 21204039; 21233212; 21346737; 21497093; 21643791; 21878642; 21900206; 21943600; 21976506; 22129841; 22430796; 22614006; 22699663; 22784093; 22794909; 22904328; 22948661; 23065961; 23163744; 23266749; 23778582; 23926262; 24255178 WW and C2 domain containing 1 Ensembl:ENSG00000113645 HGNC:29435 HPRD:10033 MIM:610533 Vega:OTTHUMG00000130408 WWC1 Bin Zhao, Yue Liu, Oliver He ATAG1874 WEB: http://www.ncbi.nlm.nih.gov/gene NCSTN nicastrin 23385 RP11-517F10.1 1q22-q23 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0002262 (EC: IEA); GO_0004175 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12297508); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005783 (EC: IDA, PMID: 15274632); GO_0005783 (EC: ISS); GO_0005794 (EC: IDA, PMID: 15274632); GO_0005794 (EC: ISS); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 15274632); GO_0005887 (EC: ISS); GO_0006508 (EC: NAS, PMID: 10993067); GO_0006509 (EC: IDA, PMID: 15274632); GO_0006509 (EC: ISS); GO_0007219 (EC: TAS); GO_0007220 (EC: TAS, PMID: 15274632); GO_0016021 (EC: NAS, PMID: 10993067); GO_0016485 (EC: IDA, PMID: 15274632); GO_0016485 (EC: ISS); GO_0022617 (EC: TAS); GO_0030198 (EC: TAS); GO_0031293 (EC: TAS); GO_0042098 (EC: IEA); GO_0042470 (EC: IEA); GO_0042987 (EC: TAS, PMID: 15274632); GO_0043065 (EC: TAS); GO_0043085 (EC: IDA, PMID: 15274632); GO_0043085 (EC: ISS); GO_0048011 (EC: TAS); GO_0050435 (EC: IEA); GO_0050673 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867); GO_0097190 (EC: TAS) PMID: 9039502; 10993067; 11295540; 11396676; 11483961; 11726200; 11943765; 11992262; 12021275; 12032140; 12044882; 12048259; 12054507; 12130643; 12198112; 12297508; 12419494; 12471034; 12477932; 12603837; 12643545; 12644462; 12660785; 12679784; 12692078; 12736250; 12740439; 12754519; 12763021; 12787561; 12815056; 12821663; 12843241; 12857757; 12917438; 14572442; 14593096; 14602727; 14642438; 14664923; 15146197; 15157994; 15189355; 15210705; 15249634; 15257293; 15274632; 15322084; 15322109; 15474363; 15489334; 15567563; 15591316; 15711015; 15721744; 15975090; 16303145; 16423463; 16630834; 16641999; 16938437; 17081065; 17192785; 17897319; 17986144; 18201567; 18667537; 19028695; 19056867; 19077115; 19105203; 19187441; 19322201; 19394408; 19684016; 19729449; 19840113; 20224929; 20880607; 20929727; 21123562; 21364883; 21412258; 21430701; 21495993; 21674799; 21725355; 21848507; 21906983; 21963094; 21987572; 22086926; 22268729; 22358060; 22404891; 22405046; 22586122; 22590650; 22622421; 22779921; 22787765; 22834455; 22939629; 23012411; 23096707; 23517242; 23585889; 23595812 nicastrin Ensembl:ENSG00000162736 HGNC:17091 HPRD:05584 MIM:605254 Vega:OTTHUMG00000033110 NCSTN Bin Zhao, Yue Liu, Oliver He SIR2L5 WEB: http://www.ncbi.nlm.nih.gov/gene SIRT5 sirtuin 5 23408 6p23 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0003950 (EC: TAS, Qualifier: NOT, PMID: 17456799); GO_0005634 (EC: TAS); GO_0005739 (EC: IDA); GO_0005758 (EC: IDA, PMID: 18680753); GO_0005759 (EC: IDA, PMID: 18680753); GO_0005829 (EC: IDA); GO_0006342 (EC: TAS, PMID: 10381378); GO_0006471 (EC: TAS, Qualifier: NOT, PMID: 17456799); GO_0006476 (EC: IDA, PMID: 18680753); GO_0006476 (EC: IDA, Qualifier: NOT); GO_0008270 (EC: IDA); GO_0036047 (EC: IDA); GO_0036048 (EC: IDA); GO_0036049 (EC: IDA); GO_0036054 (EC: IDA); GO_0036055 (EC: IDA); GO_0070403 (EC: IDA); GO_2000378 (EC: IDA) PMID: 10381378; 10873683; 11076863; 11256614; 12477932; 14574404; 14702039; 15489334; 15489336; 16079181; 16381901; 16484774; 16712791; 16827919; 17456799; 17715127; 18029348; 18680753; 19135889; 20800603; 20877624; 20887790; 21139048; 21143562; 21832049; 21908771; 22076378; 22585829; 22767592; 23028781; 23475622; 24140062; 24163370; 24250222 sirtuin 5 Ensembl:ENSG00000124523 HGNC:14933 HPRD:06838 MIM:604483 Vega:OTTHUMG00000014278 SIRT5 Bin Zhao, Yue Liu, Oliver He SIR2L4 WEB: http://www.ncbi.nlm.nih.gov/gene SIRT4 sirtuin 4 23409 12q 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0003950 (EC: IDA, PMID: 16959573); GO_0003950 (EC: TAS, PMID: 17456799); GO_0005515 (EC: IPI, PMID: 16959573); GO_0005739 (EC: IDA, PMID: 16079181); GO_0005759 (EC: IDA, PMID: 16959573); GO_0006342 (EC: TAS, PMID: 10381378); GO_0006471 (EC: ISS); GO_0006471 (EC: TAS, PMID: 17456799); GO_0006541 (EC: ISS); GO_0006974 (EC: ISS); GO_0034979 (EC: IDA, Qualifier: NOT, PMID: 17715127); GO_0034983 (EC: ISS); GO_0046322 (EC: ISS); GO_0046676 (EC: IMP, PMID: 17715127); GO_0046872 (EC: IEA); GO_0046889 (EC: ISS); GO_0070403 (EC: IEA); GO_0072350 (EC: ISS) PMID: 9847074; 10381378; 10873683; 12477932; 15122253; 15342556; 15489334; 16079181; 16541075; 16959573; 17456799; 17715127; 19209188; 21556116; 22770219; 23044393; 23045395; 23663782; 24250222 sirtuin 4 Ensembl:ENSG00000089163 HGNC:14932 HPRD:06837 MIM:604482 Vega:OTTHUMG00000169028 SIRT4 Bin Zhao, Yue Liu, Oliver He SIR2L3 WEB: http://www.ncbi.nlm.nih.gov/gene SIRT3 sirtuin 3 23410 11p15.5 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0003950 (EC: TAS, Qualifier: NOT, PMID: 17456799); GO_0005515 (EC: IPI, PMID: 16788062); GO_0005739 (EC: IDA, PMID: 16079181); GO_0005759 (EC: IEA); GO_0006471 (EC: TAS, Qualifier: NOT, PMID: 17456799); GO_0006476 (EC: IDA, PMID: 16788062); GO_0008270 (EC: IDA, PMID: 19535340); GO_0009060 (EC: IMP); GO_0016020 (EC: IEA); GO_0032041 (EC: IEA); GO_0034983 (EC: IMP); GO_0070403 (EC: IEA) PMID: 8889548; 10381378; 10873683; 11056054; 12186850; 12374852; 12477932; 15489334; 15676284; 15719057; 16079181; 16169070; 16189514; 16788062; 17059877; 17437997; 17456799; 17715127; 17957139; 18215119; 18680753; 18710944; 18781224; 19209188; 19240061; 19343720; 19367319; 19535340; 19680556; 19714312; 20129246; 20132432; 20159966; 20198340; 20463968; 20661474; 20800603; 20819778; 20877624; 20945913; 21358671; 21397863; 21449565; 21460842; 21566644; 21701047; 21840382; 22155639; 22326535; 22416140; 22585829; 22589271; 22595756; 22609775; 22674009; 22750084; 22770219; 23045395; 23046812; 23075334; 23139766; 23272146; 23397292; 23665396; 23790338; 23800187; 23856293; 23868064; 23898059; 23956348; 24026423; 24121500; 24194516; 24324009 sirtuin 3 Ensembl:ENSG00000142082 HGNC:14931 HPRD:06836 MIM:604481 Vega:OTTHUMG00000119074 SIRT3 Bin Zhao, Yue Liu, Oliver He SIR2L1 WEB: http://www.ncbi.nlm.nih.gov/gene SIRT1 sirtuin 1 23411 RP11-57G10.3 10q21.3 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0000012 (EC: IMP); GO_0000122 (EC: IDA, PMID: 12535671); GO_0000122 (EC: IMP); GO_0000183 (EC: IDA, PMID: 18485871); GO_0000720 (EC: IMP); GO_0000731 (EC: ISS); GO_0000790 (EC: IDA, PMID: 17505061); GO_0001525 (EC: IDA); GO_0001542 (EC: IEA); GO_0001678 (EC: ISS); GO_0001934 (EC: ISS); GO_0002039 (EC: IPI, PMID: 11672523); GO_0002821 (EC: IDA); GO_0003714 (EC: IDA, PMID: 12535671); GO_0003714 (EC: ISS); GO_0003950 (EC: TAS, Qualifier: NOT, PMID: 17456799); GO_0004407 (EC: IDA); GO_0005515 (EC: IPI, PMID: 11672523); GO_0005634 (EC: IDA); GO_0005635 (EC: IDA, PMID: 15469825); GO_0005637 (EC: IDA, PMID: 15469825); GO_0005654 (EC: IDA, PMID: 16079181); GO_0005677 (EC: IDA, PMID: 18485871); GO_0005719 (EC: IDA, PMID: 15469825); GO_0005720 (EC: IDA, PMID: 15469825); GO_0005730 (EC: IDA, PMID: 15469825); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005737 (EC: IDA, Qualifier: NOT, PMID: 15469825); GO_0005739 (EC: IDA); GO_0006260 (EC: TAS, PMID: 17317627); GO_0006281 (EC: TAS, PMID: 17317627); GO_0006342 (EC: TAS, PMID: 10381378); GO_0006343 (EC: IDA, PMID: 15469825); GO_0006344 (EC: IMP, PMID: 15469825); GO_0006346 (EC: TAS); GO_0006351 (EC: IEA); GO_0006364 (EC: IEA); GO_0006471 (EC: TAS, Qualifier: NOT, PMID: 17456799); GO_0006476 (EC: IDA, PMID: 18203716); GO_0006476 (EC: IMP, PMID: 11672523); GO_0006642 (EC: ISS); GO_0006974 (EC: IDA, PMID: 18203716); GO_0006979 (EC: IDA, PMID: 14976264); GO_0007283 (EC: IEA); GO_0007346 (EC: IDA, PMID: 15692560); GO_0007517 (EC: IEA); GO_0007569 (EC: TAS, PMID: 11672523); GO_0008022 (EC: IPI, PMID: 18203716); GO_0008284 (EC: IMP); GO_0009267 (EC: ISS); GO_0010875 (EC: ISS); GO_0010906 (EC: ISS); GO_0016032 (EC: IEA); GO_0016239 (EC: IDA, PMID: 18296641); GO_0016567 (EC: IDA); GO_0016575 (EC: IDA, PMID: 12006491); GO_0016605 (EC: IDA, PMID: 12006491); GO_0017136 (EC: IDA, PMID: 12006491); GO_0018394 (EC: IMP, PMID: 18004385); GO_0019213 (EC: IDA, PMID: 18203716); GO_0030308 (EC: IMP, PMID: 17505061); GO_0030512 (EC: ISS); GO_0031393 (EC: ISS); GO_0031648 (EC: ISS); GO_0031937 (EC: IMP, PMID: 15469825); GO_0032007 (EC: IMP); GO_0032071 (EC: IMP, PMID: 19934257); GO_0032088 (EC: IDA, PMID: 15152190); GO_0032868 (EC: ISS); GO_0033158 (EC: IMP, PMID: 18203716); GO_0033553 (EC: IDA, PMID: 18485871); GO_0033558 (EC: IDA, PMID: 19934257); GO_0034391 (EC: ISS); GO_0034979 (EC: IDA); GO_0034979 (EC: IMP, PMID: 11672523); GO_0034983 (EC: IDA, PMID: 15469825); GO_0035098 (EC: IDA, Qualifier: colocalizes_with, PMID: 15684044); GO_0035356 (EC: ISS); GO_0035358 (EC: ISS); GO_0042127 (EC: IMP, PMID: 12006491); GO_0042326 (EC: IMP, PMID: 17612497); GO_0042393 (EC: IPI, PMID: 15469825); GO_0042542 (EC: IDA, PMID: 19934257); GO_0042632 (EC: ISS); GO_0042771 (EC: IMP); GO_0042802 (EC: IPI, PMID: 15469825); GO_0043065 (EC: IDA, PMID: 15152190); GO_0043065 (EC: IMP, PMID: 19047049); GO_0043066 (EC: IMP, PMID: 16892051); GO_0043124 (EC: IDA, PMID: 17680780); GO_0043161 (EC: IMP); GO_0043280 (EC: IMP, PMID: 19047049); GO_0043398 (EC: IPI, PMID: 12535671); GO_0043425 (EC: IPI, PMID: 12535671); GO_0043433 (EC: IDA, PMID: 11672523); GO_0043433 (EC: IMP, PMID: 17505061); GO_0043518 (EC: IDA, PMID: 11672523); GO_0045348 (EC: IDA); GO_0045599 (EC: ISS); GO_0045739 (EC: IMP, PMID: 19934257); GO_0045892 (EC: IDA, PMID: 11672523); GO_0045944 (EC: IDA); GO_0046628 (EC: IDA); GO_0046872 (EC: IEA); GO_0046969 (EC: ISS); GO_0050872 (EC: ISS); GO_0051019 (EC: IPI); GO_0051097 (EC: IDA, PMID: 18203716); GO_0051898 (EC: IMP); GO_0055089 (EC: ISS); GO_0060766 (EC: IMP, PMID: 17505061); GO_0070301 (EC: IDA); GO_0070403 (EC: IEA); GO_0070857 (EC: ISS); GO_0070932 (EC: IDA); GO_0070932 (EC: IMP, PMID: 17505061); GO_0071356 (EC: IDA, PMID: 15152190); GO_0071456 (EC: IMP); GO_0071479 (EC: ISS); GO_1902166 (EC: ISS, PMID: 11672522); GO_1902176 (EC: IMP, PMID: 17317627); GO_2000111 (EC: ISS); GO_2000480 (EC: IDA); GO_2000481 (EC: IMP, PMID: 18687677); GO_2000655 (EC: IMP, PMID: 17505061); GO_2000757 (EC: IDA); GO_2000773 (EC: IDA); GO_2000774 (EC: IDA, PMID: 18687677) PMID: 10381378; 10873683; 11230166; 11672522; 11672523; 12006491; 12297502; 12413881; 12477932; 12535671; 12930829; 12939617; 14702039; 14976264; 14980222; 15126506; 15152190; 15164054; 15175761; 15205477; 15302935; 15469825; 15489334; 15632193; 15639232; 15640142; 15684044; 15692560; 15719057; 15744310; 15749705; 15780941; 16079181; 16154098; 16166628; 16183991; 16207712; 16257164; 16269335; 16288004; 16328012; 16344560; 16354677; 16385451; 16628003; 16751189; 16892051; 16923962; 16959573; 16964243; 16998474; 16998810; 17041012; 17081983; 17098745; 17099246; 17112576; 17172643; 17180656; 17213307; 17283066; 17317627; 17334224; 17373700; 17456799; 17487425; 17505061; 17516504; 17581637; 17601350; 17612497; 17624472; 17638871; 17680780; 17785417; 17806102; 17895433; 17901049; 17916362; 17934453; 17936707; 17937892; 17964266; 17996922; 18004385; 18029348; 18174544; 18184747; 18193082; 18203716; 18230337; 18235501; 18235502; 18296641; 18329615; 18342601; 18344999; 18414679; 18438697; 18482975; 18485871; 18485895; 18556572; 18563176; 18573234; 18636124; 18660489; 18662546; 18662547; 18681908; 18687677; 18689793; 18704159; 18723829; 18724249; 18755897; 18774777; 18800364; 18820948; 18821472; 18823944; 18829436; 18829956; 18834855; 18835033; 18838864; 18850005; 18922603; 18957417; 18977241; 19008647; 19014491; 19017485; 19047049; 19060927; 19071085; 19075016; 19104446; 19132007; 19149601; 19166820; 19167483; 19188449; 19218236; 19220062; 19229036; 19236849; 19244234; 19267881; 19285077; 19286634; 19289152; 19322201; 19343720; 19364925; 19376817; 19377286; 19404850; 19430421; 19433578; 19478080; 19491102; 19498162; 19509139; 19553684; 19555662; 19568959; 19578370; 19581416; 19615732; 19643082; 19649206; 19664641; 19680556; 19690166; 19713122; 19714620; 19716821; 19720090; 19741164; 19786632; 19819989; 19883617; 19887452; 19895790; 19923004; 19934257; 19934264; 19995796; 19996091; 20027304; 20033348; 20041875; 20042607; 20060806; 20068143; 20071779; 20089851; 20100829; 20102704; 20103737; 20107110; 20131294; 20157519; 20160399; 20167603; 20203304; 20217115; 20225204; 20335544; 20360068; 20375098; 20379614; 20412117; 20421294; 20426787; 20431927; 20439735; 20448046; 20451257; 20463039; 20479254; 20484414; 20488443; 20493163; 20503258; 20506278; 20555380; 20595232; 20617556; 20620956; 20627091; 20631301; 20633545; 20668205; 20668706; 20670893; 20689156; 20693263; 20702418; 20733005; 20803525; 20812964; 20813124; 20817729; 20819794; 20844277; 20869593; 20941378; 20955178; 20956937; 20966076; 20972425; 20977650; 20978007; 21030595; 21056897; 21067862; 21074897; 21098725; 21108727; 21118843; 21130087; 21139048; 21144831; 21149449; 21149730; 21163946; 21176092; 21212262; 21241768; 21245135; 21245319; 21277951; 21289058; 21329659; 21331741; 21337390; 21345792; 21349544; 21390332; 21414717; 21454709; 21471201; 21474819; 21501079; 21502801; 21502975; 21504832; 21505241; 21527554; 21533107; 21543634; 21555002; 21556116; 21567102; 21596753; 21604001; 21636977; 21697093; 21698133; 21700104; 21701047; 21703114; 21713995; 21719763; 21720722; 21745208; 21746786; 21760635; 21775285; 21778425; 21789216; 21807113; 21810449; 21813271; 21832856; 21852339; 21865267; 21871827; 21882241; 21890473; 21906983; 21915620; 21920899; 21947282; 21956116; 21963094; 21968188; 21972126; 21987377; 22000456; 22013015; 22017869; 22038097; 22050448; 22073865; 22094255; 22094256; 22121772; 22124156; 22133824; 22137654; 22146883; 22149272; 22152608; 22157007; 22157016; 22159506; 22169038; 22178470; 22190034; 22190494; 22197555; 22198152; 22200427; 22207735; 22219708; 22228742; 22230810; 22245592; 22249256; 22266962; 22272724; 22302044; 22306819; 22308024; 22312127; 22322739; 22328728; 22330808; 22333659; 22340598; 22355666; 22363646; 22364258; 22370592; 22378745; 22385246; 22389628; 22406815; 22410779; 22446626; 22448750; 22465953; 22479397; 22493485; 22510409; 22537175; 22542455; 22552445; 22553202; 22554968; 22564731; 22584570; 22586264; 22590959; 22613205; 22623155; 22628222; 22640743; 22661383; 22674476; 22683003; 22683888; 22689577; 22696478; 22700961; 22703651; 22728651; 22732402; 22735644; 22740055; 22773876; 22780949; 22789853; 22796962; 22807441; 22824213; 22833338; 22836009; 22863883; 22867969; 22885181; 22893703; 22902550; 22902626; 22934845; 22935421; 22939629; 22980663; 22986535; 22986747; 22990118; 22995302; 23024800; 23038275; 23045412; 23050959; 23056314; 23070058; 23075334; 23079621; 23133645; 23135526; 23137540; 23143889; 23169992; 23178529; 23209300; 23224247; 23224434; 23238746; 23247197; 23247634; 23248098; 23255128; 23257246; 23262029; 23267107; 23276927; 23305113; 23332867; 23340254; 23349863; 23354305; 23357110; 23361587; 23363613; 23365135; 23370328; 23382074; 23382833; 23390957; 23395904; 23417673; 23449222; 23450480; 23453030; 23473037; 23474493; 23475622; 23483263; 23505545; 23548308; 23561972; 23583951; 23602568; 23613875; 23661372; 23673452; 23702379; 23704280; 23754392; 23760629; 23768087; 23770291; 23797802; 23800577; 23814050; 23827175; 23855981; 23877372; 23892437; 23897426; 23922917; 23952905; 23993977; 24039251; 24126058; 24141423; 24147777; 24184811; 24211209; 24211575; 24218438; 24507186 sirtuin 1 Ensembl:ENSG00000096717 HGNC:14929 HPRD:08381 MIM:604479 Vega:OTTHUMG00000018340 SIRT1 Bin Zhao, Yue Liu, Oliver He Nomo PM5 WEB: http://www.ncbi.nlm.nih.gov/gene NOMO1 NODAL modulator 1 23420 16p13.11 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0003674 (EC: ND); GO_0005575 (EC: ND); GO_0008150 (EC: ND); GO_0016021 (EC: IEA); GO_0030246 (EC: IEA) PMID: 1310294; 8076819; 9267806; 10493829; 12477932; 15231747; 15231748; 15257293; 15616553; 15862967; 16169070; 16713569; 21319273; 21890473; 21906983; 21963094; 21987572; 21988832; 22268729; 22505724; 22832245; 22939629; 22990118; 23000965; 24250222 NODAL modulator 1 Ensembl:ENSG00000103512 HGNC:30060 HPRD:11398 MIM:609157 Vega:OTTHUMG00000090541 NOMO1 Bin Zhao, Yue Liu, Oliver He ALS10 TDP-43 WEB: http://www.ncbi.nlm.nih.gov/gene TARDBP TAR DNA binding protein 23435 RP4-635E18.2 1p36.22 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000166 (EC: IEA); GO_0003690 (EC: IDA, PMID: 7745706); GO_0003700 (EC: TAS, PMID: 7745706); GO_0003723 (EC: IDA, PMID: 11285240); GO_0003730 (EC: IDA, PMID: 17481916); GO_0005515 (EC: IPI); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0006366 (EC: TAS, PMID: 7745706); GO_0006397 (EC: IEA); GO_0008219 (EC: IEA); GO_0008380 (EC: IDA, PMID: 11285240); GO_0042802 (EC: IPI); GO_0043922 (EC: IDA, PMID: 7745706); GO_0044822 (EC: IDA); GO_0070935 (EC: IDA, PMID: 17481916) PMID: 7745706; 8125298; 8599929; 8889548; 11076863; 11230166; 11256614; 11285240; 11470789; 12361981; 12477932; 15231747; 15489334; 15489336; 16157593; 16169070; 16381901; 16710414; 17023659; 17081983; 17360763; 17481916; 17492294; 17569066; 17614162; 17623298; 17643375; 17653732; 17981595; 18029348; 18068872; 18087705; 18088371; 18206910; 18288693; 18304732; 18305110; 18305152; 18309045; 18372902; 18377426; 18379440; 18391021; 18396105; 18438952; 18505686; 18506455; 18520774; 18545701; 18546284; 18549326; 18584184; 18592312; 18634762; 18656473; 18657254; 18703504; 18723384; 18723524; 18755042; 18779421; 18802454; 18843496; 18923836; 18929508; 18931000; 18957508; 18974920; 18989684; 19018245; 19039597; 19048944; 19066918; 19111550; 19112176; 19125255; 19139310; 19139911; 19164285; 19191304; 19204154; 19204172; 19217189; 19224587; 19225410; 19228676; 19235466; 19236453; 19237541; 19283396; 19285963; 19303844; 19306141; 19330339; 19338576; 19350673; 19383787; 19411082; 19422539; 19455346; 19465477; 19471022; 19515851; 19526244; 19533646; 19560462; 19609911; 19618195; 19664364; 19685386; 19695877; 19714537; 19738201; 19760257; 19781077; 19786775; 19798749; 19808791; 19815002; 19816201; 19833869; 19851068; 19864663; 19864664; 19887443; 19910924; 19938687; 19944744; 19959528; 20008652; 20020773; 20031275; 20043239; 20047951; 20055380; 20071528; 20082726; 20133711; 20154090; 20154440; 20175762; 20225928; 20236174; 20301623; 20301761; 20360068; 20372915; 20423455; 20447446; 20472325; 20519548; 20530643; 20551689; 20554523; 20555136; 20558162; 20558945; 20577002; 20600671; 20621187; 20624952; 20645878; 20669025; 20675015; 20697052; 20702714; 20708823; 20720006; 20720505; 20736350; 20804554; 20864052; 20933032; 20937952; 20948999; 20951205; 20959352; 21062285; 21086759; 21118398; 21120508; 21123567; 21126161; 21131904; 21139048; 21145461; 21172843; 21172844; 21206091; 21209826; 21220647; 21243369; 21252943; 21257637; 21339291; 21355045; 21358640; 21376022; 21403029; 21412434; 21418058; 21421050; 21450909; 21452073; 21454603; 21454607; 21471218; 21487023; 21508314; 21541367; 21647631; 21651514; 21666678; 21667065; 21678031; 21706176; 21753175; 21783252; 21830155; 21832049; 21853274; 21881207; 21890473; 21899152; 21903422; 21906983; 21933185; 21943958; 21946215; 21956716; 21956718; 21963094; 21987572; 22029574; 22079093; 22100394; 22118674; 22127299; 22133803; 22147697; 22156203; 22177996; 22193716; 22235134; 22252998; 22257502; 22268729; 22292843; 22323604; 22327514; 22363618; 22398199; 22405725; 22406069; 22414730; 22424122; 22446626; 22456481; 22493728; 22505724; 22506890; 22539017; 22539580; 22550220; 22563080; 22575358; 22578468; 22584570; 22623428; 22674379; 22674575; 22691390; 22693459; 22718532; 22732773; 22751105; 22751173; 22752089; 22764223; 22797246; 22797925; 22804696; 22835933; 22855830; 22860700; 22872699; 22873561; 22900096; 22939629; 22941224; 22944662; 22957047; 22970712; 22990118; 23000965; 23022214; 23023293; 23041957; 23048034; 23053136; 23062702; 23092511; 23097605; 23124365; 23138004; 23231971; 23235148; 23258539; 23300771; 23317354; 23327806; 23372158; 23384725; 23389994; 23449777; 23475610; 23475817; 23541532; 23546887; 23558684; 23559573; 23587065; 23604587; 23664753; 23686809; 23689371; 23703321; 23704877; 23721326; 23737961; 23742895; 23798571; 23840565; 23874513; 24080705; 24240615; 24298989; 24457600; 24507183; 24507191 TAR DNA binding protein HGNC:11571 HPRD:05466 MIM:605078 TARDBP Bin Zhao, Yue Liu, Oliver He CMS WEB: http://www.ncbi.nlm.nih.gov/gene CD2AP CD2-associated protein 23607 6p12 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0001726 (EC: IDA, PMID: 10339567); GO_0005172 (EC: IEA); GO_0005200 (EC: TAS, PMID: 10339567); GO_0005515 (EC: IPI, PMID: 10339567); GO_0005737 (EC: TAS, PMID: 10339567); GO_0005886 (EC: IEA); GO_0006461 (EC: TAS, PMID: 10339567); GO_0006930 (EC: TAS, PMID: 10339567); GO_0007067 (EC: IEA); GO_0007165 (EC: NAS, PMID: 10339567); GO_0008013 (EC: IEA); GO_0008022 (EC: IEA); GO_0015629 (EC: TAS, PMID: 10339567); GO_0016050 (EC: IEA); GO_0016337 (EC: IEA); GO_0017124 (EC: IPI, PMID: 10339567); GO_0030139 (EC: IEA); GO_0031941 (EC: IDA, PMID: 10339567); GO_0032403 (EC: IEA); GO_0043161 (EC: IEA); GO_0045296 (EC: IEA); GO_0048259 (EC: IEA); GO_0048471 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 8889548; 9741631; 10339567; 10913159; 10997929; 11067845; 11733557; 12029088; 12477932; 12530983; 12559036; 12618476; 12672817; 12690097; 12764198; 14679214; 14736876; 15128873; 15489334; 15592455; 15659563; 15800069; 16344560; 16678097; 16707503; 16895919; 17020880; 17072306; 17081983; 17188587; 17283187; 17428861; 17474147; 17606992; 17713465; 17823309; 17853893; 17922258; 18029348; 18396147; 18654987; 18753381; 18791326; 19056867; 19131354; 19380743; 19738201; 19945749; 19956976; 20360068; 20379614; 20404345; 20457601; 20515931; 20654576; 20697350; 21460840; 21460841; 21519904; 21655212; 21706016; 21822214; 21890473; 21911934; 21963094; 21988832; 22412018; 22623428; 22706086; 22745667; 22863883; 22880102; 22939629; 23279575; 24039852; 24167568; 24322428 CD2-associated protein Ensembl:ENSG00000198087 HGNC:14258 HPRD:05026 MIM:604241 Vega:OTTHUMG00000014799 CD2AP Bin Zhao, Yue Liu, Oliver He ASP2 BACE HSPC104 WEB: http://www.ncbi.nlm.nih.gov/gene BACE1 beta-site APP-cleaving enzyme 1 23621 11q23.2-q23.3 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0004190 (EC: IDA, PMID: 10531052); GO_0005768 (EC: IDA, PMID: 10531052); GO_0005783 (EC: IEA); GO_0005794 (EC: IDA, PMID: 10531052); GO_0005802 (EC: IDA, PMID: 11466313); GO_0005887 (EC: IDA, PMID: 12586838); GO_0006508 (EC: IDA, PMID: 10531052); GO_0006509 (EC: TAS, PMID: 12354787); GO_0008798 (EC: TAS, PMID: 10591214); GO_0009986 (EC: IEA); GO_0016021 (EC: NAS, PMID: 10531052); GO_0019899 (EC: IPI, PMID: 12586838); GO_0030424 (EC: IEA); GO_0030659 (EC: IEA); GO_0050435 (EC: IDA, PMID: 15080893) PMID: 10531052; 10574461; 10591213; 10591214; 10656250; 10677483; 10749877; 10801872; 10887202; 10956649; 11021803; 11032903; 11152683; 11234778; 11266439; 11278841; 11466313; 11516562; 11684351; 11714100; 11741910; 11744168; 11847218; 11860271; 11922623; 11953458; 12054507; 12054559; 12093293; 12112088; 12135764; 12206667; 12223024; 12270690; 12354787; 12438920; 12445809; 12471021; 12477932; 12514700; 12535780; 12586836; 12586838; 12618121; 12649271; 12665519; 12707937; 12801932; 12824768; 12857759; 12901838; 12928915; 14507929; 14567678; 14681914; 14699153; 14701757; 14748006; 14748707; 14978286; 14991462; 15034149; 15059975; 15059977; 15080893; 15096037; 15117318; 15197182; 15211591; 15213451; 15234966; 15247262; 15286784; 15451669; 15452128; 15466887; 15485862; 15489334; 15491607; 15584902; 15592644; 15606899; 15615712; 15628850; 15671026; 15749709; 15784960; 15824102; 15857888; 15880353; 15886016; 15931081; 16027115; 16033761; 16181410; 16243299; 16246054; 16249081; 16279945; 16303743; 16342950; 16354928; 16449801; 16605258; 16611980; 16679558; 16716081; 16757811; 16769154; 16816111; 16897184; 16908986; 16965550; 16979658; 17113083; 17174011; 17236572; 17293612; 17307738; 17331621; 17409228; 17425515; 17511654; 17576410; 17596706; 17601350; 17699523; 17854420; 17897958; 17961921; 18039469; 18163181; 18177262; 18182389; 18182766; 18255190; 18263584; 18307033; 18374657; 18378702; 18393796; 18434550; 18581272; 18587408; 18632981; 18650447; 18660751; 18695061; 18790604; 18798280; 18805488; 18977241; 19011241; 19056495; 19057901; 19074428; 19106624; 19153172; 19196715; 19251705; 19302194; 19344981; 19372755; 19405102; 19429494; 19462468; 19508864; 19682432; 19815556; 19827607; 19889475; 19968762; 20041192; 20066010; 20080541; 20089133; 20127045; 20164582; 20212127; 20236612; 20354142; 20455082; 20468060; 20484053; 20607864; 20685197; 20726888; 20806954; 20849576; 20853423; 20854419; 20930275; 20930286; 20946940; 21209097; 21245145; 21321391; 21354237; 21440067; 21500352; 21565331; 21576249; 21585286; 21642424; 21695060; 21707077; 21712774; 21726644; 21779381; 21795680; 21825135; 21942621; 22045484; 22052506; 22122287; 22122349; 22150401; 22178568; 22194329; 22223639; 22267734; 22275252; 22299711; 22303960; 22306812; 22351782; 22450048; 22491325; 22553349; 22709416; 22721728; 22726800; 22728099; 22775589; 22796214; 22846573; 22879628; 22952813; 22975420; 22988240; 23021373; 23023105; 23024787; 23036023; 23036978; 23048024; 23109336; 23127467; 23142975; 23180460; 23202730; 23312803; 23324234; 23344193; 23504710; 23577068; 23676825; 23681056; 23701002; 23713656 beta-site APP-cleaving enzyme 1 Ensembl:ENSG00000186318 HGNC:933 HPRD:07255 MIM:604252 Vega:OTTHUMG00000160636 BACE1 Bin Zhao, Yue Liu, Oliver He IBSN SNDI p62 WEB: http://www.ncbi.nlm.nih.gov/gene NUP62 nucleoporin 62kDa 23636 19q13.33 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000278 (EC: TAS); GO_0000922 (EC: IEA); GO_0003682 (EC: NAS, PMID: 11852044); GO_0005487 (EC: NAS, Qualifier: contributes_to, PMID: 8589458); GO_0005515 (EC: IPI, PMID: 10356400); GO_0005635 (EC: IDA); GO_0005635 (EC: TAS); GO_0005643 (EC: IDA, PMID: 1915414); GO_0005643 (EC: ISS); GO_0005737 (EC: NAS, PMID: 10373430); GO_0005975 (EC: TAS); GO_0006351 (EC: IDA, PMID: 10373430); GO_0006351 (EC: ISS); GO_0006913 (EC: NAS, PMID: 8589458); GO_0007077 (EC: TAS); GO_0007166 (EC: IDA, PMID: 10799545); GO_0007166 (EC: ISS); GO_0007166 (EC: NAS, PMID: 10373430); GO_0007569 (EC: IEA); GO_0008219 (EC: IMP, PMID: 11244088); GO_0008219 (EC: ISS); GO_0008285 (EC: IDA, PMID: 11013214); GO_0008285 (EC: ISS); GO_0008645 (EC: TAS); GO_0009755 (EC: NAS, PMID: 15625236); GO_0009966 (EC: NAS, PMID: 8702753); GO_0010827 (EC: TAS); GO_0015031 (EC: IEA); GO_0015758 (EC: TAS); GO_0016032 (EC: TAS); GO_0017056 (EC: IEA); GO_0019221 (EC: TAS); GO_0030159 (EC: IDA, PMID: 11244088); GO_0030159 (EC: ISS); GO_0030529 (EC: IDA, PMID: 18809582); GO_0031074 (EC: NAS, PMID: 8589458); GO_0031965 (EC: IDA); GO_0042059 (EC: IEA); GO_0042169 (EC: IDA, PMID: 8650207); GO_0042169 (EC: ISS); GO_0043066 (EC: IDA, PMID: 11755531); GO_0043066 (EC: ISS); GO_0043069 (EC: IDA, PMID: 11244088); GO_0043069 (EC: ISS); GO_0043123 (EC: IDA, PMID: 10356400); GO_0043123 (EC: ISS); GO_0043130 (EC: IDA, PMID: 8702753); GO_0043130 (EC: ISS); GO_0043231 (EC: IDA); GO_0043407 (EC: IEA); GO_0044281 (EC: TAS); GO_0045742 (EC: NAS, PMID: 11244088); GO_0045893 (EC: IDA, PMID: 15625236); GO_0045893 (EC: ISS); GO_0046578 (EC: NAS, PMID: 11553620); GO_0046580 (EC: IEA); GO_0046930 (EC: NAS, PMID: 15175862); GO_0046966 (EC: IPI, PMID: 15625236); GO_0046966 (EC: ISS); GO_0051028 (EC: IEA); GO_0051425 (EC: IEA); GO_0055085 (EC: TAS) PMID: 1915414; 7744965; 8125298; 8537436; 8589458; 8650207; 8702753; 8707840; 8757804; 8889548; 9102465; 9114010; 9348540; 9367915; 9407313; 10330396; 10356400; 10373430; 10395558; 10601273; 10668806; 10781837; 10799545; 11013214; 11073998; 11076863; 11113176; 11230166; 11238447; 11244088; 11256614; 11266456; 11310559; 11425870; 11553620; 11755531; 11852044; 12163599; 12228227; 12477932; 12894213; 14667819; 14702039; 14718703; 15175862; 15489334; 15489336; 15507209; 15522285; 15625236; 15820316; 15953362; 16169070; 16189514; 16314397; 16344560; 16381901; 16434389; 16648475; 16730000; 16786527; 17098863; 17500061; 17960595; 18029348; 18292223; 18809582; 18854154; 19144712; 19615732; 19828735; 20360068; 20622012; 21078624; 21139048; 21145461; 21698267; 21726808; 21890473; 21906983; 21988832; 22110128; 22308026; 22334672; 22505724; 22558357; 22928108; 22939629; 23383273; 23777819; 24074597; 24250222 nucleoporin 62kDa Ensembl:ENSG00000213024 HGNC:8066 HPRD:05782 MIM:605815 Vega:OTTHUMG00000183077 NUP62 Bin Zhao, Yue Liu, Oliver He FKBP38 FKBPr38 WEB: http://www.ncbi.nlm.nih.gov/gene FKBP8 FK506 binding protein 8, 38kDa 23770 19p12 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000413 (EC: IBA); GO_0003755 (EC: IBA); GO_0005515 (EC: IPI, PMID: 16844119); GO_0005528 (EC: IBA); GO_0005740 (EC: IBA); GO_0006457 (EC: IEA); GO_0006915 (EC: IEA); GO_0016032 (EC: IEA); GO_0018208 (EC: IBA); GO_0030176 (EC: IBA); GO_0031966 (EC: IEA); GO_0035556 (EC: TAS, PMID: 10197430); GO_0042802 (EC: IPI, PMID: 17024179); GO_0046872 (EC: IEA) PMID: 7543869; 8889548; 10197430; 11076863; 11230166; 12477932; 12510191; 12894220; 15057824; 15105374; 15489334; 15489336; 15592455; 15733859; 15757646; 15990872; 16169070; 16176796; 16341674; 16381901; 16604427; 16844119; 17024179; 17082457; 17090549; 17353276; 17379601; 17569659; 17573772; 17942410; 17986458; 17991864; 18216108; 18385096; 18459960; 18658153; 18676370; 19147576; 19222999; 19546213; 19615732; 20029029; 20048149; 20139069; 20140889; 20707607; 20877624; 21044950; 21139048; 21145461; 21320469; 21360678; 21559462; 21737445; 21890473; 21906983; 21988832; 22030396; 22474283; 22523079; 22645275; 22797925; 22810585; 22939629; 23000965; 23455922; 23464991; 23602568; 23798571 FK506 binding protein 8, 38kDa Ensembl:ENSG00000105701 HGNC:3724 HPRD:05327 MIM:604840 Vega:OTTHUMG00000183368 FKBP8 Bin Zhao, Yue Liu, Oliver He AUTS15 CASPR2 CDFE NRXN4 PTHSL1 WEB: http://www.ncbi.nlm.nih.gov/gene CNTNAP2 contactin associated protein-like 2 26047 7q35 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0005769 (EC: IDA, PMID: 19706678); GO_0005794 (EC: IDA, PMID: 19166515); GO_0007155 (EC: IEA); GO_0007420 (EC: TAS, PMID: 10624965); GO_0007612 (EC: IMP, PMID: 18179893); GO_0008038 (EC: NAS, PMID: 10624965); GO_0008076 (EC: IDA, PMID: 10624965); GO_0009986 (EC: IDA, PMID: 19706678); GO_0016020 (EC: IDA, PMID: 10624965); GO_0016021 (EC: NAS, PMID: 11352571); GO_0019226 (EC: NAS, PMID: 11352571); GO_0019899 (EC: IPI, PMID: 19166515); GO_0021756 (EC: IEP, PMID: 18179893); GO_0021761 (EC: IEP, PMID: 18179895); GO_0021794 (EC: IEP, PMID: 18179893); GO_0021987 (EC: IEP, PMID: 18179893); GO_0030424 (EC: ISS); GO_0030425 (EC: ISS); GO_0030534 (EC: IMP, PMID: 18179893); GO_0030673 (EC: IDA, PMID: 19706678); GO_0031175 (EC: ISS); GO_0034613 (EC: ISS); GO_0035176 (EC: IMP, PMID: 18179893); GO_0043025 (EC: ISS); GO_0043204 (EC: ISS); GO_0044224 (EC: ISS); GO_0045163 (EC: ISS); GO_0071109 (EC: IEP, PMID: 18179893); GO_0071205 (EC: ISS); GO_0071625 (EC: IMP, PMID: 18179893) PMID: 10048485; 10624965; 11352571; 12093160; 12421765; 12477932; 12542678; 12690205; 12809671; 12853948; 12963709; 12975355; 14702039; 15203218; 15489334; 16571880; 17392702; 17646849; 17903296; 18179893; 18179894; 18179895; 18496130; 18512134; 18957941; 18987363; 19086053; 19166515; 19546859; 19582487; 19706678; 19889080; 19896112; 19913121; 20157312; 20176116; 20200978; 20379614; 20414140; 20421335; 20446882; 20502679; 20628086; 20711234; 20808326; 20889312; 21048216; 21193173; 21310003; 21387375; 21448237; 21565611; 21827697; 21906983; 21987501; 22031302; 22159054; 22365836; 22429864; 22500773; 22589738; 22690117; 22728895; 22744455; 22872700; 22948383; 23074245; 23115634; 23123147; 23192594; 23251661; 23277129; 23382691; 23407760; 23459443; 23871450 contactin associated protein-like 2 Ensembl:ENSG00000174469 HGNC:13830 HPRD:05197 MIM:604569 Vega:OTTHUMG00000152743 CNTNAP2 Bin Zhao, Yue Liu, Oliver He GAPD2 GAPDH-2 GAPDS HSD-35 WEB: http://www.ncbi.nlm.nih.gov/gene GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 26330 HSD35 19q13.12 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0004365 (EC: TAS, PMID: 10714828); GO_0005515 (EC: IPI, PMID: 16820410); GO_0005829 (EC: TAS); GO_0005975 (EC: TAS); GO_0006006 (EC: TAS); GO_0006094 (EC: TAS); GO_0006096 (EC: IEA); GO_0006096 (EC: TAS); GO_0007286 (EC: IEA); GO_0030317 (EC: ISS); GO_0031514 (EC: IEA); GO_0044281 (EC: TAS); GO_0045821 (EC: TAS, PMID: 10714828); GO_0050661 (EC: IEA); GO_0051287 (EC: IEA) PMID: 2793178; 4349855; 8125298; 9264469; 10655454; 10714828; 11225901; 11330647; 12477932; 15057824; 15342556; 15489334; 15507493; 16324157; 16700075; 16820410; 16832079; 17047026; 17192785; 17353931; 18298375; 18654987; 20534741; 20828617; 20833277; 20880607; 21269272; 21832049; 21995946; 23026046; 23306140; 23675907 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Ensembl:ENSG00000105679 HGNC:24864 HPRD:13566 MIM:609169 Vega:OTTHUMG00000182298 GAPDHS Bin Zhao, Yue Liu, Oliver He BM-018 CD358 DR6 WEB: http://www.ncbi.nlm.nih.gov/gene TNFRSF21 tumor necrosis factor receptor superfamily, member 21 27242 UNQ437/PRO868 6p21.1 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0001783 (EC: ISS); GO_0002250 (EC: ISS); GO_0005515 (EC: IPI, PMID: 19225519); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 19654028); GO_0006915 (EC: IMP); GO_0006959 (EC: ISS); GO_0030424 (EC: IEA); GO_0030889 (EC: ISS); GO_0031226 (EC: ISS); GO_0031642 (EC: IMP); GO_0042130 (EC: ISS); GO_0042552 (EC: ISS); GO_0044255 (EC: TAS); GO_0044281 (EC: TAS); GO_0048713 (EC: ISS); GO_0050852 (EC: ISS); GO_0051402 (EC: ISS); GO_0071356 (EC: IDA, PMID: 19654028); GO_0097252 (EC: ISS); GO_2000663 (EC: ISS); GO_2000666 (EC: ISS); GO_2001180 (EC: ISS) PMID: 9714541; 11485735; 11714751; 11753679; 12477932; 12975309; 14574404; 14702039; 15301860; 15489334; 15623156; 16378686; 17962943; 18029348; 19165232; 19225519; 19322201; 19654028; 20237496; 20819778; 21337622; 21501873; 21900206; 22297296; 22525750; 22567163; 22761420; 24374337 tumor necrosis factor receptor superfamily, member 21 Ensembl:ENSG00000146072 HGNC:13469 HPRD:05759 MIM:605732 Vega:OTTHUMG00000014796 TNFRSF21 Bin Zhao, Yue Liu, Oliver He PCDH-X PCDH11 PCDHX WEB: http://www.ncbi.nlm.nih.gov/gene PCDH11X protocadherin 11 X-linked 27328 RP13-138P15.1 Xq21.3 20140408 9606 X protein-coding Official from a nomenclature committee GO_0005509 (EC: IEA); GO_0005886 (EC: TAS, PMID: 10644456); GO_0005887 (EC: TAS, PMID: 10644456); GO_0007156 (EC: IEA); GO_0010923 (EC: IDA, PMID: 19389623) PMID: 8619474; 8889548; 9110174; 10644456; 10716726; 10718198; 10817752; 10835267; 11003707; 12815422; 14660691; 14727141; 15772651; 15905963; 16825765; 16874762; 18029348; 18187620; 18502103; 19125366; 19136949; 19389623; 19859901; 20523261; 20555150; 20574532; 20707987; 21276771; 22744706; 22808956; 23600975 protocadherin 11 X-linked Ensembl:ENSG00000102290 HGNC:8656 HPRD:02215 MIM:300246 Vega:OTTHUMG00000021965 PCDH11X Bin Zhao, Yue Liu, Oliver He ASC CARD5 TMS TMS-1 TMS1 WEB: http://www.ncbi.nlm.nih.gov/gene PYCARD PYD and CARD domain containing 29108 16p11.2 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0001773 (EC: IMP); GO_0002020 (EC: IEA); GO_0002218 (EC: IDA); GO_0002230 (EC: IEA); GO_0002277 (EC: ISS); GO_0002588 (EC: ISS); GO_0002821 (EC: IMP); GO_0005515 (EC: IPI, PMID: 11786556); GO_0005576 (EC: IEA); GO_0005634 (EC: IDA); GO_0005634 (EC: ISS); GO_0005730 (EC: IDA); GO_0005737 (EC: IDA); GO_0005737 (EC: NAS, PMID: 12019269); GO_0005739 (EC: IDA, PMID: 14730312); GO_0005783 (EC: IEA); GO_0005829 (EC: TAS); GO_0006915 (EC: TAS, PMID: 10567338); GO_0006919 (EC: NAS, PMID: 12019269); GO_0006954 (EC: IEA); GO_0007165 (EC: NAS, PMID: 12019269); GO_0008385 (EC: IDA, Qualifier: colocalizes_with, PMID: 12486103); GO_0008385 (EC: TAS, PMID: 12656673); GO_0008656 (EC: NAS, PMID: 12019269); GO_0010803 (EC: IMP, PMID: 14730312); GO_0030838 (EC: ISS); GO_0031647 (EC: ISS); GO_0032088 (EC: IMP, PMID: 16585594); GO_0032090 (EC: IPI, PMID: 15030775); GO_0032314 (EC: IEA); GO_0032611 (EC: IEA); GO_0032688 (EC: IMP, PMID: 19158675); GO_0032729 (EC: ISS); GO_0032755 (EC: ISS); GO_0032760 (EC: IMP, PMID: 16982856); GO_0033209 (EC: IDA, PMID: 12656673); GO_0035872 (EC: TAS); GO_0042104 (EC: ISS); GO_0042771 (EC: IMP, PMID: 14730312); GO_0042803 (EC: IDA, PMID: 15030775); GO_0043025 (EC: IEA); GO_0043065 (EC: IDA, PMID: 12646168); GO_0043124 (EC: IDA, PMID: 12486103); GO_0043280 (EC: IDA, PMID: 15030775); GO_0044325 (EC: IEA); GO_0044351 (EC: ISS); GO_0045087 (EC: TAS); GO_0046330 (EC: IMP); GO_0050718 (EC: IDA, PMID: 15030775); GO_0050727 (EC: IEA); GO_0050766 (EC: ISS); GO_0050829 (EC: IMP, PMID: 16982856); GO_0050870 (EC: IMP); GO_0051091 (EC: IDA, PMID: 19494289); GO_0051092 (EC: IDA, PMID: 12646168); GO_0051607 (EC: IDA); GO_0070374 (EC: IMP); GO_0071222 (EC: IDA, PMID: 12486103); GO_0071347 (EC: IDA, PMID: 12486103); GO_0071356 (EC: IDA, PMID: 12486103); GO_0071901 (EC: IDA, PMID: 12486103); GO_0072332 (EC: IMP, PMID: 14730312); GO_0072558 (EC: IDA, PMID: 12191486); GO_0072559 (EC: IDA, PMID: 15030775); GO_0090197 (EC: IMP); GO_0090200 (EC: IDA, PMID: 14730312); GO_0097169 (EC: IDA, PMID: 19158676); GO_2000406 (EC: ISS); GO_2000484 (EC: IMP, PMID: 16982856); GO_2000778 (EC: IMP, PMID: 16982856); GO_2001056 (EC: IDA, PMID: 19158676); GO_2001181 (EC: IMP, PMID: 16982856); GO_2001238 (EC: IDA, PMID: 16964285); GO_2001242 (EC: IDA, PMID: 14730312) PMID: 10567338; 10847592; 11103776; 11103777; 11250163; 11374873; 11498534; 11733524; 11786556; 11967258; 12019269; 12054656; 12191486; 12477932; 12486103; 12553049; 12615073; 12646168; 12656673; 12776200; 12800194; 12949795; 14499617; 14634131; 14643031; 14702039; 14730312; 14985395; 15020601; 15030775; 15041718; 15456791; 15489334; 15641782; 15701651; 16037825; 16189514; 16425203; 16585594; 16715133; 16777061; 16848908; 16964285; 16982856; 17048097; 17178784; 17339483; 17418785; 17599361; 17964261; 17986858; 18263805; 18311798; 18348116; 18701507; 18791131; 18945969; 19158675; 19158676; 19158679; 19201894; 19223547; 19234215; 19258216; 19324871; 19443857; 19494289; 19636848; 19661336; 19759015; 19759850; 20020448; 20140741; 20148899; 20500518; 20808838; 20926535; 21036703; 21058222; 21104989; 21270336; 21487011; 21832064; 21890473; 22230750; 22286270; 22295065; 22732093; 22931929; 22934972; 23064206; 23066025; 23090995; 23110696; 23209292; 23839215 PYD and CARD domain containing Ensembl:ENSG00000103490 HGNC:16608 HPRD:06020 MIM:606838 Vega:OTTHUMG00000176753 PYCARD Bin Zhao, Yue Liu, Oliver He DA41 DSK2 PLIC-1 UBQN XDRP1 WEB: http://www.ncbi.nlm.nih.gov/gene UBQLN1 ubiquilin 1 29979 9q22|9q21.2-q21.3 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0000502 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11076969); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA); GO_0005737 (EC: IMP, PMID: 12634373); GO_0005783 (EC: IDA, PMID: 12095988); GO_0019900 (EC: IPI, PMID: 11853878); GO_0019904 (EC: IEA); GO_0031396 (EC: IDA, PMID: 12634373); GO_0034976 (EC: IMP, PMID: 12095988); GO_0043234 (EC: IDA); GO_0048471 (EC: IDA, PMID: 12095988); GO_0048471 (EC: NAS, PMID: 11853878); GO_0071456 (EC: IMP, PMID: 12095988); GO_1902175 (EC: IMP, PMID: 12095988) PMID: 9268694; 9303440; 10390159; 10549293; 10807547; 10983987; 11076969; 11230166; 11256614; 11528422; 11827521; 11853878; 12095988; 12477932; 12634373; 14662753; 14702039; 15004330; 15147878; 15231748; 15489334; 15492808; 15745979; 15975090; 16007098; 16091357; 16159959; 16189514; 16196087; 16214290; 16278862; 16302009; 16344560; 16461334; 16504527; 16526030; 16712842; 16713569; 16725228; 16799550; 16813565; 16815845; 16862145; 16945923; 17082820; 17098253; 17558393; 17603015; 17614368; 17709205; 17947293; 18199683; 18241885; 18307982; 18340109; 18467327; 18535780; 18781797; 18953672; 18985028; 19112176; 19148225; 19815544; 19822669; 20059542; 20350585; 20379614; 20529957; 20693704; 20972266; 21139048; 21143716; 21695056; 21852239; 21890473; 21906983; 21963094; 21987572; 21988832; 22053931; 22134777; 22233804; 22272618; 22428841; 22505724; 22766032; 22863883; 22939629; 23000965; 23246001; 23307288; 23383273; 23459205; 23649778; 23663107; 23774650; 23940030 ubiquilin 1 Ensembl:ENSG00000135018 HGNC:12508 HPRD:05440 MIM:605046 Vega:OTTHUMG00000020104 UBQLN1 Bin Zhao, Yue Liu, Oliver He FPN1 HFE4 IREG1 MST079 MTP1 SLC11A3 WEB: http://www.ncbi.nlm.nih.gov/gene SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 30061 MSTP079 2q32 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0002260 (EC: IEA); GO_0003158 (EC: IEA); GO_0005381 (EC: IMP, PMID: 12091367); GO_0005515 (EC: IPI); GO_0005737 (EC: TAS, PMID: 10747949); GO_0005771 (EC: IEA); GO_0005886 (EC: IDA); GO_0005886 (EC: TAS); GO_0005887 (EC: IC, PMID: 12091367); GO_0006879 (EC: IMP, PMID: 12091367); GO_0006879 (EC: TAS); GO_0008021 (EC: IEA); GO_0009653 (EC: TAS, PMID: 10693807); GO_0016021 (EC: TAS, PMID: 10747949); GO_0034755 (EC: IMP, PMID: 12091367); GO_0043066 (EC: IEA); GO_0055085 (EC: TAS); GO_0060345 (EC: IEA); GO_0060586 (EC: IEA) PMID: 8125298; 10693807; 10747949; 10828623; 10882071; 11076863; 11230166; 11256614; 11431687; 11518736; 11774199; 11783942; 11897618; 11925460; 12091366; 12091367; 12123233; 12161425; 12376346; 12406098; 12477932; 12730114; 12857562; 12865285; 12873829; 14636642; 14636643; 14702039; 14757427; 14768003; 15075083; 15338274; 15466004; 15489334; 15489336; 15514116; 15692071; 15727899; 15831700; 15894659; 15897636; 15935710; 15942076; 15956209; 16169070; 16274220; 16280445; 16330432; 16344560; 16351644; 16381901; 16648237; 16885049; 17042772; 17135308; 17276706; 17383046; 17475779; 17486601; 17490902; 17847004; 17997113; 18160317; 18160816; 18177470; 18586377; 18646536; 18680715; 18782341; 18820912; 19066423; 19150361; 19234114; 19589941; 19610021; 19709084; 19759876; 19787796; 19846751; 19937651; 19958990; 20007457; 20230395; 20460119; 20564534; 20587610; 20655381; 20686179; 20688958; 20691492; 20739079; 21094556; 21126372; 21199650; 21231898; 21303654; 21396368; 21607294; 21890473; 22137264; 22170436; 22178646; 22246570; 22249207; 22357659; 22682226; 22682227; 22776295; 22890139; 23012398; 23065513; 23178444; 23335088; 23630227; 23640881; 23680252; 23846698 solute carrier family 40 (iron-regulated transporter), member 1 Ensembl:ENSG00000138449 HGNC:10909 HPRD:05229 MIM:604653 Vega:OTTHUMG00000132662 SLC40A1 Bin Zhao, Yue Liu, Oliver He CSEN DREAM KCHIP3 WEB: http://www.ncbi.nlm.nih.gov/gene KCNIP3 Kv channel interacting protein 3, calsenilin 30818 2q21.1 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0000122 (EC: IEA); GO_0003677 (EC: TAS, PMID: 10078534); GO_0003714 (EC: TAS, PMID: 10078534); GO_0005244 (EC: IEA); GO_0005267 (EC: IEA); GO_0005509 (EC: IEA); GO_0005634 (EC: IEA); GO_0005783 (EC: IEA); GO_0005794 (EC: IEA); GO_0005829 (EC: IEA); GO_0005886 (EC: IEA); GO_0006351 (EC: IEA); GO_0006357 (EC: TAS, PMID: 10078534); GO_0006886 (EC: IEA); GO_0006915 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10900016); GO_0008022 (EC: IEA); GO_0015459 (EC: IEA); GO_0019233 (EC: IEA); GO_0030425 (EC: IEA); GO_0032993 (EC: IEA); GO_0043523 (EC: IEA); GO_0043565 (EC: IEA); GO_0043679 (EC: IEA); GO_0044325 (EC: IEA); GO_0048266 (EC: IEA); GO_0048306 (EC: IEA) PMID: 9771752; 9819380; 10078534; 10676964; 10854253; 10900016; 11072133; 11094064; 11259376; 11278424; 11535596; 11792319; 11988022; 12006572; 12198160; 12207970; 12217801; 12451113; 12477932; 12648752; 12829703; 12837631; 14702039; 14720210; 15086516; 15184042; 15489334; 15770150; 15815621; 16112838; 16177826; 16189514; 16306395; 16840549; 17102134; 17189291; 17962406; 18187620; 18269347; 18393943; 18507845; 18628663; 18664571; 18957440; 19299442; 19730683; 20211142; 21070824; 21216226; 21813705; 21852538; 22730276; 23019329; 23187802; 23300953; 23692269; 23786773 Kv channel interacting protein 3, calsenilin Ensembl:ENSG00000115041 HGNC:15523 HPRD:05232 MIM:604662 Vega:OTTHUMG00000130392 KCNIP3 Bin Zhao, Yue Liu, Oliver He 6530402N02Rik APH-1 APH-1A CGI-78 WEB: http://www.ncbi.nlm.nih.gov/gene APH1A APH1A gamma secretase subunit 51107 RP4-790G17.3 1p36.13-q31.3 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001656 (EC: IEA); GO_0004175 (EC: IEA); GO_0005515 (EC: IPI, PMID: 12297508); GO_0005783 (EC: IDA, PMID: 15274632); GO_0005789 (EC: IEA); GO_0005794 (EC: IDA, PMID: 15274632); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 15274632); GO_0006509 (EC: IDA, PMID: 15274632); GO_0007219 (EC: TAS); GO_0007220 (EC: IMP, PMID: 12297508); GO_0007220 (EC: TAS, PMID: 15274632); GO_0016485 (EC: IDA, PMID: 15274632); GO_0031293 (EC: IMP, PMID: 12297508); GO_0031293 (EC: TAS); GO_0032580 (EC: IEA); GO_0042987 (EC: IMP, PMID: 12297508); GO_0042987 (EC: TAS, PMID: 15274632); GO_0043065 (EC: TAS); GO_0043085 (EC: IDA, PMID: 15274632); GO_0048011 (EC: TAS); GO_0097190 (EC: TAS) PMID: 10810093; 12110170; 12297508; 12471034; 12477932; 12522139; 12679784; 12740439; 12763021; 12787561; 12843241; 12857757; 12917438; 12972157; 12975309; 14572442; 14593096; 14627705; 14702039; 15210705; 15257293; 15274632; 15286082; 15322084; 15322109; 15474363; 15489334; 15629423; 15721744; 16303743; 16344560; 16630834; 16641999; 16757808; 17059559; 17207965; 17986144; 18801744; 19028695; 19322201; 19368855; 19369254; 20145246; 20299451; 20379614; 20674680; 21123562; 21443683; 21890473; 21988832; 23253155; 23291095; 23864651 APH1A gamma secretase subunit Ensembl:ENSG00000117362 HGNC:29509 MIM:607629 Vega:OTTHUMG00000012545 APH1A Bin Zhao, Yue Liu, Oliver He LEF-1 TCF10 TCF1ALPHA TCF7L3 WEB: http://www.ncbi.nlm.nih.gov/gene LEF1 lymphoid enhancer-binding factor 1 51176 4q23-q25 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0000122 (EC: IEA); GO_0000977 (EC: IDA); GO_0001228 (EC: IMP); GO_0001569 (EC: IBA); GO_0001649 (EC: IEP); GO_0001755 (EC: IBA); GO_0001756 (EC: IBA); GO_0001837 (EC: ISS); GO_0002040 (EC: IBA); GO_0003677 (EC: ISS); GO_0003682 (EC: IBA); GO_0003700 (EC: IDA, PMID: 11751639); GO_0003705 (EC: IBA); GO_0005515 (EC: IPI, PMID: 12192039); GO_0005634 (EC: IC, PMID: 9308964); GO_0005634 (EC: IDA, PMID: 17063141); GO_0005654 (EC: TAS); GO_0005667 (EC: IDA, PMID: 11751639); GO_0005737 (EC: IDA, PMID: 19402906); GO_0006366 (EC: IDA); GO_0008013 (EC: IDA, PMID: 9488439); GO_0008013 (EC: IPI, PMID: 10825188); GO_0008013 (EC: TAS, PMID: 16344550); GO_0008134 (EC: IEA); GO_0008284 (EC: IDA, PMID: 19351848); GO_0008301 (EC: ISS); GO_0010628 (EC: IDA, PMID: 16344550); GO_0010718 (EC: IMP); GO_0016055 (EC: IDA, PMID: 10644691); GO_0016202 (EC: IBA); GO_0021542 (EC: IBA); GO_0021854 (EC: IBA); GO_0021861 (EC: IBA); GO_0021873 (EC: IBA); GO_0021879 (EC: IBA); GO_0021943 (EC: IBA); GO_0022407 (EC: IEA); GO_0022408 (EC: IDA, PMID: 19653274); GO_0022409 (EC: IDA, PMID: 19653274); GO_0030223 (EC: IMP, PMID: 17063141); GO_0030284 (EC: IDA, PMID: 18794125); GO_0030307 (EC: IMP); GO_0030326 (EC: IBA); GO_0030331 (EC: IDA, PMID: 18794125); GO_0030335 (EC: IDA, PMID: 19653274); GO_0030335 (EC: IMP); GO_0030509 (EC: IBA); GO_0030854 (EC: IDA, PMID: 19620402); GO_0030854 (EC: IMP); GO_0030879 (EC: IBA); GO_0032696 (EC: IDA, PMID: 18445004); GO_0032713 (EC: IDA, PMID: 18445004); GO_0032714 (EC: IDA, PMID: 18445004); GO_0032993 (EC: IDA, PMID: 10825188); GO_0033153 (EC: IEA); GO_0035326 (EC: IDA, PMID: 7657162); GO_0042100 (EC: IBA); GO_0042393 (EC: IPI); GO_0042475 (EC: IEA); GO_0043027 (EC: IMP); GO_0043066 (EC: IMP); GO_0043154 (EC: IMP); GO_0043392 (EC: IDA, PMID: 18445004); GO_0043401 (EC: IDA, PMID: 18794125); GO_0043565 (EC: IDA, PMID: 10825188); GO_0043586 (EC: IEA); GO_0043923 (EC: IDA, PMID: 7657162); GO_0043966 (EC: IMP); GO_0043967 (EC: IMP); GO_0044212 (EC: IDA, PMID: 16344550); GO_0045063 (EC: ISS); GO_0045295 (EC: IPI, PMID: 14661054); GO_0045843 (EC: IEA); GO_0045892 (EC: IDA, PMID: 18794125); GO_0045892 (EC: IMP, PMID: 18579517); GO_0045893 (EC: IDA, PMID: 10644691); GO_0045893 (EC: IMP, PMID: 19351848); GO_0045944 (EC: IDA, PMID: 11751639); GO_0045944 (EC: IMP); GO_0046632 (EC: IBA); GO_0048069 (EC: IBA); GO_0048341 (EC: IBA); GO_0048747 (EC: IBA); GO_0050909 (EC: IEA); GO_0060021 (EC: ISS); GO_0060033 (EC: IEA); GO_0060070 (EC: IDA); GO_0060070 (EC: IMP, PMID: 19576624); GO_0060325 (EC: IBA); GO_0060326 (EC: IDA, PMID: 19576624); GO_0060561 (EC: IBA); GO_0060710 (EC: IBA); GO_0061153 (EC: IBA); GO_0070016 (EC: IPI, PMID: 12408825); GO_0070742 (EC: IPI, PMID: 18445004); GO_0071345 (EC: IMP); GO_0071353 (EC: IDA, PMID: 18579517); GO_0071864 (EC: IMP, PMID: 17063141); GO_0071866 (EC: IMP, PMID: 17063141); GO_0071895 (EC: IBA); GO_0071899 (EC: IDA, PMID: 18794125); GO_0090068 (EC: IDA, PMID: 19653274); GO_0090090 (EC: IMP, PMID: 19402906); GO_1902262 (EC: IEA) PMID: 1783375; 1827423; 1989880; 2010090; 7537238; 7657162; 7958926; 8125298; 8631802; 8757136; 9119227; 9119228; 9308964; 9419974; 9488439; 9671491; 9751710; 9843967; 10644691; 10756202; 10825188; 10890911; 10958684; 11266540; 11326276; 11440173; 11604490; 11696550; 11731474; 11751639; 11835406; 12032083; 12048204; 12052822; 12077367; 12095232; 12161443; 12183361; 12192039; 12235165; 12408825; 12446687; 12477932; 12551949; 12556497; 12589056; 12707037; 12748295; 12901858; 14661054; 14759258; 14990565; 15000148; 15143193; 15194563; 15245424; 15489334; 15525529; 15684397; 15728254; 15750622; 15756419; 15768032; 16014379; 16120831; 16142310; 16204248; 16228014; 16344550; 16415175; 16424171; 16474850; 16510874; 16510875; 16565724; 16714285; 16809766; 17063141; 17132729; 17240357; 17360796; 17466981; 17585052; 17785436; 17785445; 17947518; 17980157; 18029348; 18077326; 18296023; 18316418; 18445004; 18579517; 18615589; 18636547; 18794125; 18936100; 19060910; 19079342; 19131506; 19244345; 19304756; 19351848; 19402906; 19453261; 19460168; 19576624; 19590514; 19620402; 19653274; 19784072; 20019092; 20098615; 20124220; 20194509; 20211142; 20219685; 20332099; 20363964; 20595513; 20634891; 20676368; 21190562; 21270130; 21282610; 21285352; 21383983; 21444716; 21471213; 21527502; 21544627; 21599871; 21685909; 21744004; 21781440; 21795403; 21980470; 21988832; 21998751; 22020335; 22111711; 22261717; 22291604; 22359570; 22436613; 22505724; 22507326; 22639890; 22686279; 22766851; 22769578; 22792274; 22815426; 22837378; 22905168; 23001182; 23068607; 23224985; 23325550; 23375451; 23572277; 23770605; 23913826 lymphoid enhancer-binding factor 1 Ensembl:ENSG00000138795 HGNC:6551 HPRD:01075 MIM:153245 Vega:OTTHUMG00000131809 LEF1 Bin Zhao, Yue Liu, Oliver He CD288 WEB: http://www.ncbi.nlm.nih.gov/gene TLR8 toll-like receptor 8 51311 UNQ249/PRO286 Xp22 20140408 9606 X protein-coding Official from a nomenclature committee GO_0000139 (EC: TAS); GO_0002224 (EC: TAS); GO_0002282 (EC: IEA); GO_0003677 (EC: IDA, PMID: 16123302); GO_0003723 (EC: TAS, PMID: 16123302); GO_0003725 (EC: IDA, PMID: 16111635); GO_0003727 (EC: IDA, PMID: 14976262); GO_0004872 (EC: NAS, PMID: 12032557); GO_0005789 (EC: TAS); GO_0006954 (EC: IEA); GO_0007249 (EC: IDA, PMID: 12032557); GO_0008144 (EC: IEA); GO_0009615 (EC: IDA, PMID: 12032557); GO_0010008 (EC: TAS); GO_0016021 (EC: IC, PMID: 12032557); GO_0016064 (EC: TAS, PMID: 16123302); GO_0034162 (EC: TAS); GO_0036020 (EC: TAS); GO_0045078 (EC: IDA, PMID: 16286015); GO_0045087 (EC: NAS, PMID: 12032557); GO_0045087 (EC: TAS); GO_0045089 (EC: IDA, PMID: 16123302); GO_0045356 (EC: IDA, PMID: 16286015); GO_0045359 (EC: IDA, PMID: 16286015); GO_0045416 (EC: IMP, PMID: 16188996); GO_0051607 (EC: IMP, PMID: 16188996); GO_0052033 (EC: IEA); GO_0071260 (EC: IEP, PMID: 19593445) PMID: 9435236; 11022119; 11022120; 11607792; 11782555; 11909637; 12032557; 12477932; 12724322; 12975309; 14625308; 14976262; 15276183; 15489334; 16008579; 16024789; 16025564; 16111635; 16123302; 16188996; 16286015; 16303743; 16482509; 16737960; 16857668; 16935934; 17023556; 17040905; 17090647; 17301562; 17698957; 17703412; 17724596; 17868034; 17932028; 17964520; 18394314; 18406377; 18431484; 18438411; 18605904; 18682521; 18686608; 18810425; 18818748; 18927625; 18942751; 18985439; 18985539; 19017992; 19019335; 19028959; 19164127; 19164128; 19258923; 19265114; 19381167; 19406482; 19437550; 19454678; 19505919; 19527497; 19527514; 19593445; 19614650; 19637197; 19841637; 19850743; 19913121; 19915052; 19924287; 20004021; 20100933; 20124101; 20190752; 20194452; 20227302; 20237413; 20237496; 20364151; 20399690; 20412752; 20503287; 20588308; 20595247; 20628086; 20652908; 20674764; 20829351; 20832340; 20946625; 20977567; 21061265; 21092001; 21321205; 21354862; 21499082; 21677671; 21734241; 21947541; 21977996; 22022576; 22065095; 22164301; 22196370; 22210629; 22243920; 22289837; 22340042; 22363482; 22393042; 22525943; 22730373; 22768144; 22795647; 22857391; 23221735; 23223421; 23369718; 23386618; 23425350; 23520111; 23685782; 23787171; 23906644; 24046015; 24227841; 24254490 toll-like receptor 8 Ensembl:ENSG00000101916 HGNC:15632 HPRD:02296 MIM:300366 Vega:OTTHUMG00000021145 TLR8 Bin Zhao, Yue Liu, Oliver He CILD6 NM23-H8 SPTRX2 TXNDC3 sptrx-2 WEB: http://www.ncbi.nlm.nih.gov/gene NME8 NME/NM23 family member 8 51314 7p14.1 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0004550 (EC: IEA); GO_0005524 (EC: IEA); GO_0005737 (EC: IEA); GO_0006183 (EC: IEA); GO_0006228 (EC: IEA); GO_0006241 (EC: IEA); GO_0007275 (EC: IEA); GO_0007283 (EC: IEA); GO_0030154 (EC: IEA); GO_0045454 (EC: IEA) PMID: 11574167; 11737268; 11768308; 12477932; 15489334; 16642435; 17304710; 17360648; 18029348; 18471322; 19852809; 20237151; 20301301; 20379614; 21832049; 22504420 NME/NM23 family member 8 Ensembl:ENSG00000086288 HGNC:16473 HPRD:16243 MIM:607421 Vega:OTTHUMG00000023716 NME8 Bin Zhao, Yue Liu, Oliver He CSD PCAP WEB: http://www.ncbi.nlm.nih.gov/gene CSAD cysteine sulfinic acid decarboxylase 51380 12q13.11-q14.3 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0000096 (EC: TAS); GO_0000098 (EC: TAS); GO_0004782 (EC: IEA); GO_0030170 (EC: IEA); GO_0034641 (EC: TAS); GO_0042412 (EC: IEA); GO_0044281 (EC: TAS) PMID: 11752456; 11997111; 12477932; 14702039; 15489334; 16344560; 21900206; 22718265; 23251661; 24250222 cysteine sulfinic acid decarboxylase Ensembl:ENSG00000139631 HGNC:18966 HPRD:16763 Vega:OTTHUMG00000048076 CSAD Bin Zhao, Yue Liu, Oliver He SIR2L7 WEB: http://www.ncbi.nlm.nih.gov/gene SIRT7 sirtuin 7 51547 17q25 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0000122 (EC: IDA); GO_0003682 (EC: IDA); GO_0005515 (EC: IPI, PMID: 19174463); GO_0005730 (EC: IDA, PMID: 16079181); GO_0005731 (EC: IDA, PMID: 19174463); GO_0005737 (EC: IEA); GO_0007072 (EC: IMP, PMID: 19174463); GO_0009303 (EC: IMP, PMID: 19174463); GO_0046872 (EC: IEA); GO_0070403 (EC: IEA); GO_0070932 (EC: IDA); GO_0070933 (EC: IDA); GO_0097372 (EC: IDA) PMID: 9776767; 10873683; 11953824; 12454780; 12477932; 14702039; 15489334; 16079181; 16169070; 16525639; 16618798; 17003781; 19174463; 20375098; 21832049; 22147730; 22586326; 22722849; 23079745; 23680022; 23750001; 24207024; 24250222 sirtuin 7 Ensembl:ENSG00000187531 HGNC:14935 HPRD:12094 MIM:606212 Vega:OTTHUMG00000177957 SIRT7 Bin Zhao, Yue Liu, Oliver He SIR2L6 WEB: http://www.ncbi.nlm.nih.gov/gene SIRT6 sirtuin 6 51548 19p13.3 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0003950 (EC: TAS, PMID: 17456799); GO_0003956 (EC: ISS); GO_0005515 (EC: IPI, PMID: 19135889); GO_0005634 (EC: ISS); GO_0005654 (EC: IDA, PMID: 16079181); GO_0005724 (EC: IDA, PMID: 18337721); GO_0005730 (EC: IDA, Qualifier: NOT, PMID: 16079181); GO_0006471 (EC: ISS); GO_0006471 (EC: TAS, PMID: 17456799); GO_0008270 (EC: ISS); GO_0010569 (EC: IDA, PMID: 19135889); GO_0016575 (EC: ISS); GO_0017136 (EC: ISS); GO_0046969 (EC: IDA, PMID: 18337721); GO_0070403 (EC: ISS); GO_0070932 (EC: IDA, PMID: 18337721) PMID: 8125298; 10873683; 12477932; 14702039; 15057824; 15489334; 15719057; 16079181; 16169070; 16189514; 17131381; 17456799; 18242175; 18337721; 18388907; 19135889; 19625767; 20157594; 20375098; 20829486; 21224216; 21349544; 21362626; 21502801; 21680843; 21847107; 21890473; 21900206; 21900744; 21906983; 21981042; 22087257; 22505724; 22700961; 22743824; 22753495; 22770219; 22792191; 22939629; 23041974; 23075334; 23086953; 23132960; 23136298; 23201774; 23217706; 23514751; 23526469; 23552949; 23653361; 23860128; 24043303; 24052263; 24250222; 24367027 sirtuin 6 Ensembl:ENSG00000077463 HGNC:14934 HPRD:12093 MIM:606211 Vega:OTTHUMG00000181847 SIRT6 Bin Zhao, Yue Liu, Oliver He DC15 PEP11 WEB: http://www.ncbi.nlm.nih.gov/gene VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 51699 DC7 12q24 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0004647 (EC: IEA); GO_0005737 (EC: IDA); GO_0005768 (EC: IDA); GO_0005829 (EC: TAS); GO_0010008 (EC: IEA); GO_0015031 (EC: IEA); GO_0043231 (EC: IDA); GO_0046872 (EC: IEA) PMID: 8889549; 9700157; 11062004; 11076863; 11102511; 11230166; 11256614; 12477932; 15247922; 15282546; 15489334; 15489336; 15788412; 16169070; 16381901; 16712791; 16737443; 17101778; 17891154; 19531583; 20923837; 21629666; 21832049; 21900206; 21906983; 22354992; 22863883; 22939629; 23452853; 23455922 vacuolar protein sorting 29 homolog (S. cerevisiae) Ensembl:ENSG00000111237 HGNC:14340 HPRD:09499 MIM:606932 Vega:OTTHUMG00000169527 VPS29 Bin Zhao, Yue Liu, Oliver He PPS SKIP WEB: http://www.ncbi.nlm.nih.gov/gene INPP5K inositol polyphosphate-5-phosphatase K 51763 17p13.3 20140408 9606 17 protein-coding Official from a nomenclature committee GO_0001701 (EC: IEA); GO_0001726 (EC: IDA, PMID: 12536145); GO_0001933 (EC: ISS); GO_0004445 (EC: IEA); GO_0005000 (EC: ISS); GO_0005515 (EC: IPI, PMID: 16002321); GO_0005634 (EC: IDA, PMID: 18774950); GO_0005737 (EC: ISS); GO_0005783 (EC: IDA, PMID: 12536145); GO_0005802 (EC: IDA, PMID: 12556481); GO_0005829 (EC: IDA, PMID: 10753883); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA, PMID: 12556481); GO_0005979 (EC: ISS); GO_0006469 (EC: IDA, PMID: 12556481); GO_0006644 (EC: TAS); GO_0006661 (EC: TAS); GO_0007186 (EC: ISS); GO_0010801 (EC: IDA, PMID: 12556481); GO_0010829 (EC: IDA, PMID: 12556481); GO_0016020 (EC: IDA, PMID: 12536145); GO_0016311 (EC: IDA, PMID: 18573875); GO_0016311 (EC: IMP, PMID: 18774950); GO_0016312 (EC: IDA, PMID: 10753883); GO_0030036 (EC: NAS, PMID: 10753883); GO_0032587 (EC: IDA, PMID: 12556481); GO_0032869 (EC: IDA, PMID: 12556481); GO_0032870 (EC: ISS); GO_0033137 (EC: IDA, PMID: 12556481); GO_0034485 (EC: IDA); GO_0034594 (EC: IDA, PMID: 12556481); GO_0034595 (EC: IMP, PMID: 18774950); GO_0035305 (EC: ISS); GO_0035810 (EC: ISS); GO_0042577 (EC: NAS, PMID: 10753883); GO_0042593 (EC: ISS); GO_0043005 (EC: IDA, PMID: 10753883); GO_0043407 (EC: IDA, PMID: 12556481); GO_0043922 (EC: IDA, PMID: 18774950); GO_0044281 (EC: TAS); GO_0045719 (EC: IDA, PMID: 12556481); GO_0045869 (EC: IDA, PMID: 18774950); GO_0045892 (EC: ISS); GO_0045893 (EC: ISS); GO_0046030 (EC: IDA, PMID: 10753883); GO_0046627 (EC: IDA, PMID: 12556481); GO_0046855 (EC: IDA, PMID: 12536145); GO_0046856 (EC: IDA, PMID: 12536145); GO_0048471 (EC: IDA, PMID: 18774950); GO_0051497 (EC: IDA, PMID: 12556481); GO_0051898 (EC: IDA, PMID: 12556481); GO_0051926 (EC: IDA, PMID: 12556481); GO_0052658 (EC: IEA); GO_0052659 (EC: IEA); GO_0071320 (EC: ISS); GO_0071356 (EC: IDA); GO_0071364 (EC: IDA); GO_0072661 (EC: ISS); GO_0090315 (EC: IDA, PMID: 12556481); GO_0097178 (EC: IDA, PMID: 12556481); GO_2000466 (EC: ISS); GO_2001153 (EC: ISS) PMID: 8968499; 8968500; 10753883; 11509665; 12477932; 12536145; 12556481; 12621583; 16002321; 16189514; 17353931; 18573875; 18774950; 21890473; 21900206; 21903422; 21988832; 22751929; 22815484; 24250222 inositol polyphosphate-5-phosphatase K Ensembl:ENSG00000132376 HGNC:33882 HPRD:08489 MIM:607875 Vega:OTTHUMG00000150648 INPP5K Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene NUP54 nucleoporin 54kDa 53371 4q21.1 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0000278 (EC: TAS); GO_0005487 (EC: IEA); GO_0005635 (EC: TAS); GO_0005643 (EC: IEA); GO_0005654 (EC: TAS, PMID: 8707840); GO_0005737 (EC: TAS, PMID: 8707840); GO_0005975 (EC: TAS); GO_0006605 (EC: IEA); GO_0007077 (EC: TAS); GO_0008645 (EC: TAS); GO_0010827 (EC: TAS); GO_0015758 (EC: TAS); GO_0016032 (EC: TAS); GO_0019221 (EC: TAS); GO_0031965 (EC: IEA); GO_0044281 (EC: TAS); GO_0051028 (EC: IEA); GO_0055085 (EC: TAS) PMID: 2050741; 7531196; 8125298; 8589458; 8707840; 9582382; 10395558; 10546895; 10601273; 10931946; 11266456; 12228227; 12477932; 14702039; 15489334; 16189514; 16344560; 16651408; 17623298; 19275582; 19458171; 20012529; 20936779; 21139048; 21489275; 21890473; 21906983; 21963094; 21987572; 22939629; 23000965 nucleoporin 54kDa NUP54 Bin Zhao, Yue Liu, Oliver He CD289 WEB: http://www.ncbi.nlm.nih.gov/gene TLR9 toll-like receptor 9 54106 UNQ5798/PRO19605 3p21.3 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000139 (EC: TAS); GO_0002224 (EC: TAS); GO_0002237 (EC: TAS, PMID: 15356140); GO_0002755 (EC: IEA); GO_0004888 (EC: IEA); GO_0005149 (EC: IPI, PMID: 12925853); GO_0005576 (EC: NAS, PMID: 11130078); GO_0005737 (EC: IDA, PMID: 19740627); GO_0005764 (EC: ISS); GO_0005768 (EC: ISS); GO_0005783 (EC: ISS); GO_0005789 (EC: TAS); GO_0005886 (EC: IDA, PMID: 19740627); GO_0006954 (EC: IEA); GO_0007252 (EC: IDA, PMID: 19740627); GO_0008286 (EC: TAS); GO_0010008 (EC: TAS); GO_0016021 (EC: IEA); GO_0016323 (EC: IDA, PMID: 17128265); GO_0016324 (EC: IDA, PMID: 17128265); GO_0030277 (EC: ISS); GO_0032009 (EC: ISS); GO_0032088 (EC: IDA, PMID: 17128265); GO_0032715 (EC: ISS); GO_0032717 (EC: IDA, PMID: 17128265); GO_0032722 (EC: IDA, PMID: 19740627); GO_0032728 (EC: ISS); GO_0032733 (EC: ISS); GO_0032735 (EC: ISS); GO_0032741 (EC: ISS); GO_0032755 (EC: IDA, PMID: 19740627); GO_0032757 (EC: IDA, PMID: 17128265); GO_0032760 (EC: ISS); GO_0034122 (EC: IDA, PMID: 17128265); GO_0034123 (EC: IDA, PMID: 17128265); GO_0034162 (EC: TAS); GO_0035197 (EC: IMP, PMID: 15723075); GO_0036020 (EC: TAS); GO_0042346 (EC: IDA, PMID: 19740627); GO_0042742 (EC: NAS, PMID: 11130078); GO_0043123 (EC: IDA, PMID: 17128265); GO_0043507 (EC: IDA, PMID: 17128265); GO_0045078 (EC: IDA, PMID: 16286015); GO_0045087 (EC: TAS, PMID: 15356140); GO_0045356 (EC: IDA, PMID: 16286015); GO_0045359 (EC: IDA, PMID: 16286015); GO_0045944 (EC: ISS); GO_0046330 (EC: IC, PMID: 17128265); GO_0050707 (EC: IEA); GO_0050729 (EC: IC, PMID: 19740627); GO_0050829 (EC: IMP); GO_0051092 (EC: IDA, PMID: 17128265); GO_0051770 (EC: ISS) PMID: 9435236; 11022119; 11022120; 11130078; 11561001; 11564765; 11782555; 11867692; 11909637; 11970999; 11976718; 12477932; 12560217; 12573264; 12600829; 12660731; 12689944; 12724322; 12734363; 12778475; 12867418; 12925853; 12941697; 12975309; 14625308; 14694183; 14716310; 14751759; 14987294; 15107846; 15153500; 15207506; 15276183; 15294971; 15307186; 15356140; 15489334; 15585868; 15607737; 15631627; 15723075; 15730519; 15790341; 15860583; 15878652; 16002719; 16024265; 16024789; 16125159; 16164440; 16230478; 16237063; 16286015; 16371473; 16394009; 16424230; 16428738; 16437636; 16575840; 16608528; 16731773; 16779724; 16847112; 16849519; 16864658; 16920494; 16951309; 16971956; 16990271; 17000223; 17040905; 17075805; 17128265; 17142771; 17145922; 17192395; 17229603; 17258734; 17292969; 17295441; 17301562; 17325049; 17328813; 17344245; 17360657; 17373717; 17440926; 17469139; 17473064; 17474147; 17482427; 17516623; 17534115; 17573724; 17636117; 17703412; 17768129; 17854429; 17854755; 17878374; 17893430; 17894360; 17914947; 17932028; 17964520; 17984204; 17986857; 18036648; 18092352; 18160420; 18208876; 18215354; 18253698; 18262306; 18275280; 18312481; 18318750; 18332208; 18394314; 18406377; 18437017; 18524824; 18535206; 18539711; 18568766; 18595521; 18606688; 18633634; 18686608; 18763053; 18769358; 18776126; 18776592; 18806803; 18810425; 18818748; 18832675; 18841790; 18922969; 18946062; 19019335; 19033535; 19034349; 19050243; 19079358; 19096003; 19120473; 19129482; 19130296; 19201477; 19211891; 19247692; 19254290; 19258923; 19264973; 19275920; 19284650; 19289178; 19297619; 19299739; 19317913; 19319670; 19337058; 19362685; 19367581; 19390575; 19401392; 19406482; 19423540; 19459480; 19505919; 19513613; 19527514; 19539691; 19564354; 19578108; 19601804; 19618291; 19620253; 19627277; 19639721; 19714766; 19723394; 19724876; 19740627; 19745833; 19771452; 19789190; 19794067; 19796535; 19809335; 19810822; 19840968; 19844589; 19854217; 19855253; 19903791; 19906293; 19913121; 19914718; 19924287; 19948975; 19953283; 20026892; 20038537; 20041977; 20044998; 20054821; 20085599; 20100933; 20130217; 20132814; 20137629; 20181802; 20194452; 20197609; 20207250; 20227302; 20227772; 20237496; 20307689; 20331378; 20348497; 20363151; 20364327; 20375564; 20375566; 20399690; 20406964; 20422193; 20438785; 20442853; 20452482; 20497632; 20500814; 20503287; 20514021; 20559388; 20588308; 20592251; 20595247; 20604744; 20622911; 20628086; 20635795; 20646321; 20646633; 20659127; 20667457; 20673868; 20674764; 20696081; 20713890; 20797905; 20811701; 20819670; 20821041; 20843333; 20843814; 20935225; 20977567; 20978888; 20980519; 21048031; 21048937; 21050493; 21057083; 21059889; 21068441; 21086718; 21115235; 21129170; 21132533; 21155002; 21176371; 21191071; 21220755; 21223799; 21250838; 21258099; 21273385; 21287547; 21317915; 21324137; 21328884; 21391743; 21398612; 21425908; 21448350; 21457584; 21462132; 21483736; 21490291; 21499878; 21515789; 21527067; 21575365; 21595536; 21604257; 21607583; 21633947; 21682079; 21689850; 21703981; 21720175; 21734566; 21741080; 21748790; 21778270; 21778277; 21833528; 21843566; 21844166; 21850017; 21866115; 21876325; 21903422; 21908428; 21908957; 21911421; 21926972; 21929816; 21940676; 21968308; 21968713; 21977996; 21978158; 21990957; 22001237; 22014045; 22041559; 22046272; 22055432; 22057691; 22059466; 22065095; 22067623; 22070100; 22132241; 22169598; 22170068; 22174451; 22178715; 22196370; 22207622; 22211722; 22221660; 22228476; 22251233; 22269973; 22288832; 22344539; 22423970; 22488361; 22552867; 22554506; 22577991; 22594374; 22594608; 22613717; 22653776; 22662111; 22671429; 22672741; 22684144; 22691414; 22695187; 22701693; 22714906; 22768144; 22822061; 22836641; 22847512; 22853846; 22893852; 22898741; 22908309; 22931661; 22932083; 22948021; 22948541; 22952899; 22964787; 23009111; 23021866; 23043436; 23045477; 23071157; 23091345; 23103284; 23123793; 23133627; 23135998; 23179584; 23182970; 23183093; 23219390; 23221735; 23237868; 23266611; 23276930; 23289794; 23296704; 23369718; 23383065; 23406596; 23407387; 23425749; 23467704; 23472199; 23490285; 23497207; 23564191; 23593431; 23617757; 23651260; 23673637; 23677790; 23724117; 23752229; 23766695; 23776537; 23816930; 23827939; 23855294; 23893288; 23913633; 23957925; 23962979; 23967355; 23974872; 24004541; 24067965; 24080302; 24168509; 24269682 toll-like receptor 9 Ensembl:ENSG00000239732 HGNC:15633 HPRD:05685 MIM:605474 Vega:OTTHUMG00000158106 TLR9 Bin Zhao, Yue Liu, Oliver He CYC HCS THC4 WEB: http://www.ncbi.nlm.nih.gov/gene CYCS cytochrome c, somatic 54205 7p15.3 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0000159 (EC: TAS, PMID: 8206937); GO_0004722 (EC: TAS, Qualifier: contributes_to, PMID: 8206937); GO_0005506 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10206961); GO_0005634 (EC: IDA); GO_0005739 (EC: IDA); GO_0005743 (EC: TAS); GO_0005758 (EC: TAS, PMID: 8689682); GO_0005829 (EC: IMP, PMID: 8689682); GO_0005829 (EC: TAS); GO_0006309 (EC: IMP, PMID: 8689682); GO_0006915 (EC: TAS); GO_0008635 (EC: TAS, PMID: 9267021); GO_0016311 (EC: TAS, PMID: 8206937); GO_0020037 (EC: TAS, PMID: 9515723); GO_0022904 (EC: TAS); GO_0044237 (EC: TAS); GO_0044281 (EC: TAS); GO_0045155 (EC: IDA, PMID: 8689682); GO_0045333 (EC: TAS, PMID: 10383829); GO_0070469 (EC: IEA); GO_0097193 (EC: TAS) PMID: 199233; 1309738; 2153405; 2580882; 2844747; 2849112; 4403130; 6087732; 6088481; 6251869; 6262312; 6270113; 8206937; 8663341; 8689682; 9027314; 9192670; 9267021; 9390557; 9515723; 9615439; 9760250; 9847074; 9922454; 10082581; 10206961; 10383829; 10506125; 10622714; 10625700; 10683230; 10801801; 10818086; 10980706; 11076863; 11193032; 11230166; 11256614; 11462036; 11737208; 11739707; 11784858; 11790791; 11839755; 12019321; 12101247; 12147322; 12243190; 12404116; 12416732; 12477932; 12555167; 12690205; 12853948; 12909341; 13933734; 14063298; 14702039; 15033690; 15254227; 15489334; 15489336; 15691386; 15698476; 16196087; 16381901; 16520893; 16713569; 16934433; 17353931; 17409234; 18345000; 18417609; 18825408; 18973553; 18976975; 19029908; 19172527; 19404857; 19458171; 19640329; 19770576; 19812265; 19851871; 19875445; 19895853; 20227384; 20237496; 20877624; 20972266; 21139048; 21192676; 21319273; 21448217; 21693764; 21706253; 21712378; 21751259; 21869827; 21890473; 21906983; 22102269; 22157762; 22184220; 22192356; 22216281; 22320973; 22363611; 22505724; 22552851; 22623428; 22632162; 22939629; 23000965; 23070294; 23150584; 23207240; 23334161; 23535033; 24163370; 24250222 cytochrome c, somatic HGNC:19986 HPRD:00479 MIM:123970 CYCS Bin Zhao, Yue Liu, Oliver He TREM-2 Trem2a Trem2b Trem2c WEB: http://www.ncbi.nlm.nih.gov/gene TREM2 triggering receptor expressed on myeloid cells 2 54209 RP1-238O23.2 6p21.1 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0001530 (EC: IEA); GO_0004872 (EC: TAS, PMID: 10799849); GO_0005576 (EC: IEA); GO_0005886 (EC: TAS); GO_0006959 (EC: TAS, PMID: 10799849); GO_0007411 (EC: TAS); GO_0016021 (EC: IEA); GO_0045087 (EC: TAS) PMID: 10799849; 12080485; 12477932; 12645956; 12754369; 12913093; 12925681; 15489334; 15966270; 16505336; 16715077; 17530208; 18546367; 18551625; 19019460; 19079182; 19230638; 19457124; 19913121; 20301376; 20421649; 20628086; 20640189; 21834902; 22939635; 23150908; 23150934; 23380991; 23391427; 23407992; 23533697; 23582655; 23721075; 23759145; 23800361; 23855982; 23855984; 23870839; 24078628; 24131187 triggering receptor expressed on myeloid cells 2 Ensembl:ENSG00000095970 HGNC:17761 HPRD:05473 MIM:605086 Vega:OTTHUMG00000014671 TREM2 Bin Zhao, Yue Liu, Oliver He CD354 TREM-1 WEB: http://www.ncbi.nlm.nih.gov/gene TREM1 triggering receptor expressed on myeloid cells 1 54210 6p21.1 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0004872 (EC: TAS, PMID: 10799849); GO_0005576 (EC: IEA); GO_0005886 (EC: TAS); GO_0006959 (EC: TAS, PMID: 10799849); GO_0007596 (EC: TAS); GO_0016021 (EC: IEA); GO_0035556 (EC: TAS, PMID: 10799849); GO_0045087 (EC: TAS); GO_0050900 (EC: TAS) PMID: 8125298; 10799849; 11323674; 11922939; 12477932; 12645956; 12646648; 12792857; 14574404; 14656437; 15067076; 15309732; 15351648; 15489334; 15585833; 16344560; 16437719; 16733861; 17008237; 17202378; 17277102; 17336301; 17452516; 17505044; 17558349; 17634956; 17659879; 17729416; 17785845; 18008257; 18317529; 18396215; 18628981; 18634145; 18656898; 18818748; 19019335; 19109693; 19230638; 19251433; 19396532; 19479878; 19484952; 19527514; 19591072; 19596984; 19913121; 19917159; 19923060; 20140262; 20156945; 20237496; 20375613; 20628086; 20640189; 21148811; 21306476; 21393102; 21421043; 21555403; 21701149; 21763322; 21855288; 21906983; 21910175; 21942576; 21967868; 21976106; 22179409; 22417086; 22422501; 22459945; 22642593; 22721842; 22798017; 22829716; 22996209; 23046618; 23364598; 23414215; 23436478; 23468854; 23734253; 23861562; 23880194; 24605677 triggering receptor expressed on myeloid cells 1 Ensembl:ENSG00000124731 HGNC:17760 HPRD:05472 MIM:605085 Vega:OTTHUMG00000014674 TREM1 Bin Zhao, Yue Liu, Oliver He ZCW1 WEB: http://www.ncbi.nlm.nih.gov/gene ZCWPW1 zinc finger, CW type with PWWP domain 1 55063 7q22.1 20140408 9606 7 protein-coding Official from a nomenclature committee GO_0008270 (EC: IEA) PMID: 11230166; 12477932; 14607086; 14702039; 15489334; 20826339; 24250222 zinc finger, CW type with PWWP domain 1 Ensembl:ENSG00000078487 HGNC:23486 HPRD:15706 Vega:OTTHUMG00000159537 ZCWPW1 Bin Zhao, Yue Liu, Oliver He MEM3 PARK17 WEB: http://www.ncbi.nlm.nih.gov/gene VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 55737 TCCCTA00141 16q12 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 11102511); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005768 (EC: IDA); GO_0005829 (EC: IDA, PMID: 11102511); GO_0005829 (EC: TAS); GO_0008219 (EC: IEA); GO_0015031 (EC: IEA); GO_0030904 (EC: IEA); GO_0042147 (EC: NAS, PMID: 11102511); GO_0070062 (EC: IDA, PMID: 19056867) PMID: 8125298; 8619474; 8889548; 9110174; 11062004; 11076863; 11102511; 11112353; 11230166; 11256614; 12477932; 14702039; 15231748; 15247922; 15282546; 15489334; 15489336; 16190980; 16196087; 16335966; 16344560; 16381901; 17101778; 17215244; 17353931; 17620599; 17891154; 17897319; 17916227; 18029348; 18781797; 19056867; 19322201; 19531583; 19553991; 19615732; 19738201; 19874558; 20000738; 20164305; 20301402; 20619655; 20923837; 21139048; 21319273; 21515373; 21733561; 21763482; 21763483; 21822266; 21832049; 21849449; 21875946; 21890473; 21903422; 21906983; 21988832; 22053931; 22154191; 22278960; 22284051; 22336192; 22354992; 22410496; 22513087; 22517097; 22623428; 22673036; 22673115; 22797925; 22801713; 22863883; 22891780; 22939629; 22991136; 23125461; 23261770; 23408866; 23411763; 23452853; 23455922; 23463506; 23536430; 23726718; 24250222 vacuolar protein sorting 35 homolog (S. cerevisiae) HGNC:13487 HPRD:06085 MIM:601501 VPS35 Bin Zhao, Yue Liu, Oliver He ENA MENA NDPP1 WEB: http://www.ncbi.nlm.nih.gov/gene ENAH enabled homolog (Drosophila) 55740 RP11-496N12.7 1q42.12 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001725 (EC: IEA); GO_0001843 (EC: IEA); GO_0003779 (EC: IEA); GO_0005515 (EC: IPI, PMID: 16979624); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA); GO_0005925 (EC: IDA); GO_0007411 (EC: TAS); GO_0008154 (EC: IEA); GO_0017124 (EC: IEA); GO_0030027 (EC: IEA); GO_0030054 (EC: IDA); GO_0030175 (EC: IEA); GO_0045202 (EC: IEA); GO_0046907 (EC: IEA); GO_0050699 (EC: IPI, PMID: 17686488); GO_0050852 (EC: TAS) PMID: 1420303; 9171351; 9312002; 9407065; 9473484; 10725224; 10747096; 10801818; 10892742; 11696321; 12477932; 12571287; 12672821; 12695497; 12941633; 12967995; 14506234; 14592989; 14702039; 15027125; 15148305; 15469845; 15469846; 15489334; 15556561; 16055720; 16336193; 16494957; 16533770; 16710414; 16964243; 16979624; 17081983; 17101133; 17686488; 18029348; 18158903; 18676769; 18985426; 19081071; 19082477; 19277120; 19322201; 19434313; 19641378; 20083228; 20379614; 21044950; 21139048; 21209853; 21335464; 21398369; 21423205; 21769917; 21890473; 21988832; 22472896; 22615875; 22863883; 23000965; 23062752; 23129656; 23251661; 23602568; 24076656; 24163370 enabled homolog (Drosophila) Ensembl:ENSG00000154380 HGNC:18271 HPRD:12360 MIM:609061 Vega:OTTHUMG00000037742 ENAH Bin Zhao, Yue Liu, Oliver He HCA2 SAC SACI Sacy WEB: http://www.ncbi.nlm.nih.gov/gene ADCY10 adenylate cyclase 10 (soluble) 55811 RP1-313L4.2 1q24 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0000287 (EC: IEA); GO_0004016 (EC: NAS, PMID: 9874775); GO_0005524 (EC: IEA); GO_0005737 (EC: TAS, PMID: 9874775); GO_0005829 (EC: NAS, PMID: 9874775); GO_0005856 (EC: IEA); GO_0005886 (EC: IEA); GO_0006171 (EC: NAS, PMID: 9874775); GO_0007283 (EC: IEA); GO_0030145 (EC: IEA); GO_0030424 (EC: IEA); GO_0030425 (EC: IEA); GO_0030426 (EC: IEA); GO_0035556 (EC: IEA); GO_0043025 (EC: IEA); GO_0043065 (EC: IEA); GO_0045177 (EC: IEA); GO_0045178 (EC: IEA); GO_0048471 (EC: IEA); GO_0051117 (EC: IEA) PMID: 2165385; 7937899; 8663304; 9417641; 9694905; 9874775; 10446129; 10737962; 10915626; 11423534; 11875252; 11932268; 12475901; 12477932; 12609998; 12626323; 12958208; 14993377; 16144836; 16344560; 17591988; 18209474; 19064610; 19093065; 19536175; 20130594; 20379614; 21994938; 22775536; 23255611; 23455922; 24100033 adenylate cyclase 10 (soluble) Ensembl:ENSG00000143199 HGNC:21285 HPRD:05549 MIM:605205 Vega:OTTHUMG00000034573 ADCY10 Bin Zhao, Yue Liu, Oliver He MSTP064 PEN-2 PEN2 WEB: http://www.ncbi.nlm.nih.gov/gene PSENEN presenilin enhancer gamma secretase subunit 55851 MDS033 19q13.12 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 16641999); GO_0005783 (EC: IDA, PMID: 15274632); GO_0005789 (EC: IEA); GO_0005794 (EC: IDA, PMID: 15274632); GO_0005886 (EC: TAS); GO_0005887 (EC: IDA, PMID: 15274632); GO_0006509 (EC: IDA, PMID: 15274632); GO_0007219 (EC: TAS); GO_0007220 (EC: TAS, PMID: 15274632); GO_0016485 (EC: IDA, PMID: 15274632); GO_0031293 (EC: TAS); GO_0032580 (EC: IEA); GO_0042987 (EC: TAS, PMID: 15274632); GO_0043065 (EC: TAS); GO_0043085 (EC: IDA, PMID: 15274632); GO_0048011 (EC: TAS); GO_0097190 (EC: TAS) PMID: 12110170; 12198112; 12477932; 12522139; 12639958; 12660785; 12679784; 12740439; 12763021; 12787561; 12843241; 14572442; 15274632; 15322084; 15322109; 15474363; 15489334; 15721744; 15953349; 15975090; 16234243; 16234244; 16331303; 16449647; 16630834; 16641999; 16712791; 17280645; 17668005; 17986144; 19036728; 19889971; 20178366; 20534834; 20847418; 20929727; 21412258; 21454611; 21852538; 21988832; 22479317; 22622421; 22689582; 22787762; 23096707; 23134962; 23246698; 23685131; 24250222 presenilin enhancer gamma secretase subunit HGNC:30100 HPRD:06362 MIM:607632 PSENEN Bin Zhao, Yue Liu, Oliver He TMTSP UNQ3010 WEB: http://www.ncbi.nlm.nih.gov/gene THSD1 thrombospondin, type I, domain containing 1 55901 RP11-245D16.1 13q14.3 20140408 9606 13 protein-coding Official from a nomenclature committee GO_0002244 (EC: IEA); GO_0005576 (EC: IEA); GO_0005737 (EC: IDA); GO_0009986 (EC: IEA); GO_0016021 (EC: IEA); GO_0071944 (EC: IEA) PMID: 7687569; 12477932; 12975309; 14702039; 15057823; 15371459; 15489334; 17047544; 18029348; 18403638; 22664866 thrombospondin, type I, domain containing 1 Ensembl:ENSG00000136114 HGNC:17754 HPRD:18180 Vega:OTTHUMG00000016963 THSD1 Bin Zhao, Yue Liu, Oliver He CRAM CRMP-5 CRMP5 Ulip6 WEB: http://www.ncbi.nlm.nih.gov/gene DPYSL5 dihydropyrimidinase-like 5 56896 2p23.3 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0005829 (EC: TAS); GO_0006208 (EC: IEA); GO_0007165 (EC: TAS, PMID: 10851247); GO_0007399 (EC: TAS, PMID: 10851247); GO_0007411 (EC: TAS); GO_0016812 (EC: IEA); GO_0030425 (EC: IEA); GO_0043025 (EC: IEA) PMID: 10851247; 10956643; 11034345; 11220734; 11549731; 12093729; 12134159; 12477932; 12838519; 14702039; 15489334; 16169070; 16344560; 18306241; 18347453; 18769332; 18854154; 18931014; 21139048; 21988832; 22581228; 23251661; 23298946; 23373749; 24324268 dihydropyrimidinase-like 5 Ensembl:ENSG00000157851 HGNC:20637 HPRD:10522 MIM:608383 Vega:OTTHUMG00000097071 DPYSL5 Bin Zhao, Yue Liu, Oliver He NET59 WEB: http://www.ncbi.nlm.nih.gov/gene NCLN nicalin 56926 19p13.3 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 17261586); GO_0005789 (EC: IEA); GO_0008233 (EC: IEA); GO_0009966 (EC: IEA); GO_0016021 (EC: IEA) PMID: 11076863; 11230166; 12477932; 14702039; 15057824; 15257293; 15489334; 15489336; 16196087; 16381901; 17261586; 18029348; 21139048; 21890473; 21906983; 21963094; 21987572; 22268729; 22505724; 22939629 nicalin Ensembl:ENSG00000125912 HGNC:26923 HPRD:07126 MIM:609156 Vega:OTTHUMG00000180687 NCLN Bin Zhao, Yue Liu, Oliver He LALP1 WEB: http://www.ncbi.nlm.nih.gov/gene ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 57089 RP11-483F11.1 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0016021 (EC: IEA); GO_0016787 (EC: IEA); GO_0030659 (EC: IEA); GO_0046872 (EC: IEA) PMID: 11278936; 12477932; 14702039; 15164054; 15489334; 20534741; 22412388 ectonucleoside triphosphate diphosphohydrolase 7 HGNC:19745 HPRD:10939 ENTPD7 Bin Zhao, Yue Liu, Oliver He C20orf32 CAS4 HEFL HEPL WEB: http://www.ncbi.nlm.nih.gov/gene CASS4 Cas scaffolding protein family member 4 57091 20q13.31 20140408 9606 20 protein-coding Official from a nomenclature committee GO_0000155 (EC: IEA); GO_0005737 (EC: IEA); GO_0005856 (EC: IEA); GO_0005925 (EC: IEA); GO_0007155 (EC: IEA); GO_0016020 (EC: IEA) PMID: 11780052; 12477932; 14702039; 15489334; 16344560; 18256281; 19380743; 23001926 Cas scaffolding protein family member 4 Ensembl:ENSG00000087589 HGNC:15878 HPRD:09842 Vega:OTTHUMG00000032788 CASS4 Bin Zhao, Yue Liu, Oliver He CARD12 CLAN CLAN1 CLANA CLANB CLANC CLAND CLR2.1 IPAF WEB: http://www.ncbi.nlm.nih.gov/gene NLRC4 NLR family, CARD domain containing 4 58484 UNQ6189/PRO20215 2p22-p21 20140408 9606 2 protein-coding Official from a nomenclature committee GO_0000287 (EC: TAS, PMID: 15882992); GO_0002218 (EC: ISS); GO_0005515 (EC: IPI, PMID: 11374873); GO_0005524 (EC: IDA, PMID: 15882992); GO_0005622 (EC: NAS, PMID: 15107016); GO_0005829 (EC: ISS); GO_0005829 (EC: TAS); GO_0006919 (EC: IDA, PMID: 15030775); GO_0006954 (EC: ISS); GO_0016045 (EC: IDA, PMID: 15107016); GO_0035872 (EC: TAS); GO_0042742 (EC: IDA, PMID: 15107016); GO_0042802 (EC: IPI, PMID: 11374873); GO_0042803 (EC: IDA, PMID: 15107016); GO_0043065 (EC: IDA, PMID: 12646168); GO_0045087 (EC: TAS); GO_0050702 (EC: IDA, PMID: 15882992); GO_0051092 (EC: IDA, PMID: 12646168); GO_0051260 (EC: ISS); GO_0070269 (EC: ISS); GO_0072557 (EC: ISS) PMID: 11374873; 11390368; 11472070; 12477932; 12545166; 12646168; 12975309; 14702039; 15030775; 15107016; 15174051; 15489334; 15528373; 15580302; 15882992; 16817903; 17418785; 17620097; 18453601; 20085538; 20349122; 21918512; 22227487; 22547706; 23012363; 23215645 NLR family, CARD domain containing 4 Ensembl:ENSG00000091106 HGNC:16412 HPRD:06014 MIM:606831 Vega:OTTHUMG00000152107 NLRC4 Bin Zhao, Yue Liu, Oliver He ACUG BLAU CARD15 CD CLR16.3 IBD1 NLRC2 NOD2B PSORAS1 WEB: http://www.ncbi.nlm.nih.gov/gene NOD2 nucleotide-binding oligomerization domain containing 2 64127 16q21 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0000187 (EC: TAS); GO_0002224 (EC: TAS); GO_0002227 (EC: IEA); GO_0002282 (EC: IEA); GO_0002367 (EC: IMP, PMID: 16260731); GO_0002381 (EC: IEA); GO_0002606 (EC: ISS); GO_0002710 (EC: IEA); GO_0002732 (EC: IEA); GO_0002755 (EC: TAS); GO_0002756 (EC: TAS); GO_0002830 (EC: IMP); GO_0002862 (EC: IEA); GO_0002925 (EC: IEA); GO_0005515 (EC: IPI, PMID: 11472070); GO_0005524 (EC: IEA); GO_0005737 (EC: IDA); GO_0005737 (EC: TAS, PMID: 15967716); GO_0005829 (EC: IDA, PMID: 15998797); GO_0005829 (EC: TAS); GO_0005856 (EC: IDA); GO_0005886 (EC: IDA, PMID: 15998797); GO_0006952 (EC: TAS, PMID: 15967716); GO_0006965 (EC: IEA); GO_0007254 (EC: TAS); GO_0007584 (EC: IEA); GO_0008180 (EC: IDA, Qualifier: colocalizes_with, PMID: 17337451); GO_0009595 (EC: TAS, PMID: 15967716); GO_0009986 (EC: IDA, PMID: 16714539); GO_0016045 (EC: IDA, PMID: 15653568); GO_0019899 (EC: IPI, PMID: 15753091); GO_0019901 (EC: IPI, PMID: 15075345); GO_0030277 (EC: IMP, PMID: 17058067); GO_0031982 (EC: IDA, PMID: 15998797); GO_0032088 (EC: IEA); GO_0032495 (EC: IDA, PMID: 15998797); GO_0032496 (EC: IEA); GO_0032498 (EC: IDA, PMID: 12527755); GO_0032500 (EC: IDA, PMID: 15998797); GO_0032689 (EC: IEA); GO_0032695 (EC: IEA); GO_0032701 (EC: IEA); GO_0032703 (EC: IEA); GO_0032720 (EC: IEA); GO_0032731 (EC: IMP); GO_0032733 (EC: ISS); GO_0032735 (EC: IEA); GO_0032740 (EC: IMP, PMID: 17919942); GO_0032755 (EC: IDA, PMID: 16414084); GO_0032760 (EC: IDA, PMID: 17187069); GO_0032760 (EC: IMP); GO_0032874 (EC: IDA, PMID: 17187069); GO_0034134 (EC: TAS); GO_0034136 (EC: IEA); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0034146 (EC: TAS); GO_0034162 (EC: TAS); GO_0034166 (EC: TAS); GO_0035419 (EC: ISS); GO_0035556 (EC: IDA, PMID: 15653568); GO_0035666 (EC: TAS); GO_0035872 (EC: TAS); GO_0038123 (EC: TAS); GO_0038124 (EC: TAS); GO_0042742 (EC: IDA, PMID: 15653568); GO_0042834 (EC: IDA, PMID: 15998797); GO_0043123 (EC: IDA, PMID: 11087742); GO_0043234 (EC: IDA); GO_0043330 (EC: IEA); GO_0043552 (EC: ISS); GO_0044130 (EC: IEA); GO_0045087 (EC: IDA); GO_0045087 (EC: NAS, PMID: 17690884); GO_0045087 (EC: TAS); GO_0045747 (EC: ISS); GO_0045944 (EC: IDA); GO_0046330 (EC: IDA, PMID: 17187069); GO_0046645 (EC: ISS); GO_0050679 (EC: ISS); GO_0050700 (EC: IPI, PMID: 11087742); GO_0050718 (EC: IDA, PMID: 15107016); GO_0050727 (EC: IC, PMID: 11385577); GO_0050731 (EC: IEA); GO_0050766 (EC: IEA); GO_0050830 (EC: IEA); GO_0050871 (EC: IDA); GO_0051092 (EC: IDA, PMID: 11385577); GO_0051092 (EC: TAS); GO_0051259 (EC: TAS, PMID: 15967716); GO_0051353 (EC: ISS); GO_0051403 (EC: TAS); GO_0051770 (EC: ISS); GO_0052033 (EC: IEA); GO_0060585 (EC: ISS); GO_0070374 (EC: ISS); GO_0070423 (EC: TAS); GO_0070431 (EC: IDA, PMID: 12527755); GO_0071224 (EC: IEA); GO_0071225 (EC: IDA); GO_0071608 (EC: IEA); GO_0090022 (EC: IEA); GO_2000110 (EC: ISS); GO_2000363 (EC: ISS) PMID: 7809109; 8587604; 8894707; 9541106; 9797359; 9924607; 10053016; 10439963; 11087742; 11318544; 11385576; 11385577; 11425413; 11472070; 11528384; 11752413; 11834373; 11837220; 11875755; 11890351; 11910336; 11910337; 11938034; 11976792; 12019209; 12019468; 12020527; 12105836; 12105838; 12115195; 12115249; 12198692; 12202985; 12210321; 12360101; 12397216; 12415614; 12454871; 12459523; 12474146; 12492195; 12508397; 12512038; 12512064; 12514169; 12527755; 12529700; 12532667; 12556233; 12563685; 12577202; 12595627; 12595906; 12617879; 12618963; 12626759; 12631666; 12631668; 12631669; 12649405; 12650796; 12671896; 12671897; 12673278; 12704363; 12810925; 12823148; 12851870; 12871942; 12876263; 12879366; 12923865; 12930309; 12940436; 13680285; 14508222; 14516815; 14522785; 14555911; 14597055; 14627676; 14638352; 14644139; 14690304; 14743885; 14747834; 14750643; 14971813; 14996717; 15002819; 15008984; 15016407; 15024686; 15044951; 15046221; 15046222; 15052696; 15056084; 15075345; 15090455; 15095853; 15107016; 15107849; 15140210; 15142196; 15145460; 15168811; 15180737; 15190267; 15194649; 15202784; 15214053; 15276183; 15279649; 15289769; 15308523; 15320482; 15367194; 15377357; 15459013; 15468360; 15472511; 15479689; 15489579; 15492242; 15515785; 15516360; 15520108; 15527324; 15539411; 15539413; 15551253; 15571586; 15571588; 15578724; 15620648; 15626887; 15626888; 15637755; 15638227; 15643611; 15653568; 15654786; 15655821; 15666202; 15667501; 15685536; 15712650; 15753091; 15770725; 15778542; 15785318; 15795594; 15800781; 15803022; 15807862; 15812565; 15840263; 15842589; 15843082; 15927452; 15930978; 15967635; 15967716; 15973116; 15973118; 15984988; 15990626; 15998797; 16000642; 16002353; 16008671; 16009674; 16010583; 16080653; 16115863; 16126943; 16133971; 16134725; 16134731; 16148063; 16161956; 16167972; 16174099; 16179784; 16198136; 16203728; 16230083; 16239840; 16239841; 16244543; 16255050; 16257953; 16260731; 16266221; 16267612; 16278823; 16279904; 16306764; 16315780; 16319062; 16344053; 16344054; 16385250; 16389181; 16393227; 16397396; 16402184; 16414084; 16416181; 16424393; 16436969; 16437636; 16437728; 16441470; 16446977; 16454837; 16461743; 16485124; 16489646; 16492792; 16493424; 16493449; 16494109; 16494592; 16510569; 16519819; 16522788; 16534418; 16611251; 16614992; 16641610; 16642031; 16669960; 16670523; 16670524; 16714539; 16716969; 16741608; 16771961; 16773683; 16804398; 16804670; 16819374; 16825909; 16840031; 16897777; 16907704; 16920047; 16933467; 16949315; 16952484; 16965521; 16977346; 17005562; 17006998; 17009307; 17012967; 17018387; 17020469; 17030188; 17057186; 17058067; 17068223; 17096091; 17100974; 17100976; 17101573; 17113749; 17119385; 17131470; 17142621; 17156146; 17156193; 17157607; 17160430; 17171451; 17174426; 17187069; 17200669; 17206080; 17206636; 17206688; 17258734; 17269998; 17278126; 17285593; 17301648; 17303577; 17319929; 17333217; 17337451; 17337463; 17348859; 17351900; 17355968; 17356065; 17379562; 17389014; 17389035; 17393391; 17403538; 17404888; 17417801; 17420470; 17435756; 17447842; 17451203; 17452051; 17460484; 17476680; 17484863; 17484864; 17486745; 17489054; 17498224; 17509030; 17538984; 17548659; 17554300; 17558494; 17558906; 17563761; 17565648; 17570063; 17595233; 17600378; 17613538; 17620097; 17652449; 17660460; 17661913; 17666747; 17684544; 17690884; 17703412; 17705850; 17719742; 17724347; 17725592; 17763471; 17786191; 17804789; 17852840; 17876878; 17877509; 17892524; 17894849; 17907287; 17911997; 17919942; 17941079; 17964196; 17964870; 17965022; 17968944; 17976376; 17978873; 17980027; 18022867; 18022871; 18028374; 18047543; 18052659; 18069758; 18088053; 18090989; 18092344; 18092345; 18096043; 18157816; 18158963; 18162085; 18166373; 18182678; 18184136; 18200509; 18200510; 18213697; 18219096; 18227809; 18240302; 18243161; 18248772; 18253730; 18256385; 18271063; 18305068; 18317454; 18329614; 18340358; 18341489; 18367950; 18371139; 18371140; 18382655; 18383179; 18384487; 18413660; 18419343; 18433468; 18438406; 18466472; 18489434; 18507017; 18521914; 18521924; 18541930; 18563169; 18573991; 18574154; 18576390; 18587394; 18594982; 18617779; 18619921; 18633131; 18640012; 18647548; 18670786; 18676680; 18680223; 18698678; 18715515; 18756601; 18758419; 18758464; 18787464; 18804983; 18818748; 18819462; 18824555; 18855982; 18938111; 18942751; 18942754; 18972554; 18976442; 18985712; 19019335; 19050632; 19058231; 19074885; 19079230; 19098858; 19103524; 19103559; 19112191; 19116920; 19120480; 19139201; 19169908; 19170196; 19174806; 19183163; 19184348; 19184350; 19189651; 19200604; 19219079; 19235913; 19240061; 19244164; 19247692; 19253375; 19258923; 19262523; 19266573; 19273470; 19275920; 19299732; 19305026; 19319132; 19337309; 19337385; 19349988; 19397946; 19406482; 19422935; 19423540; 19426395; 19434699; 19479836; 19479837; 19482182; 19527514; 19535145; 19570052; 19570976; 19572373; 19579027; 19579029; 19590455; 19592251; 19625176; 19638967; 19641059; 19659808; 19664207; 19667203; 19679065; 19679608; 19692168; 19693669; 19701189; 19701969; 19713276; 19721713; 19728064; 19748964; 19759286; 19760754; 19787357; 19809335; 19822951; 19826411; 19830732; 19843337; 19853919; 19880660; 19888426; 19896081; 19898471; 19907652; 19912254; 19913121; 19948723; 19966812; 20002790; 20018961; 20024904; 20027650; 20032092; 20047977; 20066736; 20079790; 20082483; 20087966; 20110711; 20124104; 20140262; 20155851; 20177049; 20182871; 20230816; 20232407; 20298285; 20332463; 20346235; 20350193; 20362271; 20371648; 20373538; 20379614; 20380008; 20384614; 20385562; 20387682; 20403997; 20406964; 20412372; 20428899; 20436512; 20438785; 20441518; 20452482; 20453000; 20483763; 20485703; 20503287; 20524760; 20525885; 20537165; 20541026; 20549515; 20565245; 20570966; 20583427; 20595247; 20601676; 20622911; 20628086; 20632099; 20637199; 20646002; 20646321; 20673868; 20676658; 20698950; 20713205; 20800603; 20839241; 20844241; 20850627; 20854823; 20865702; 20875485; 20886065; 20940596; 20959815; 20962850; 21039068; 21040192; 21040358; 21042538; 21097508; 21102463; 21123652; 21155887; 21206965; 21209938; 21215810; 21218092; 21241317; 21263023; 21274544; 21310790; 21335489; 21337670; 21342182; 21343918; 21385537; 21388357; 21391291; 21410503; 21448648; 21460759; 21565239; 21573891; 21596301; 21625457; 21659536; 21665963; 21690088; 21699783; 21716313; 21730793; 21734346; 21734790; 21739538; 21744420; 21745302; 21745515; 21768114; 21799103; 21887730; 21906983; 21914217; 21943069; 21978001; 22139875; 22147245; 22212192; 22218461; 22244368; 22266421; 22275320; 22286692; 22289211; 22319155; 22346247; 22397822; 22412388; 22416979; 22426692; 22464675; 22502597; 22504414; 22509093; 22549783; 22563200; 22571967; 22607974; 22665475; 22684479; 22700971; 22719818; 22730064; 22739221; 22795647; 22807259; 22815893; 22829933; 22879519; 22936669; 22997500; 22998942; 23019338; 23085276; 23100559; 23102769; 23109427; 23121969; 23128233; 23173613; 23287275; 23300079; 23322906; 23409731; 23437331; 23493074; 23558906; 23594678; 23615072; 23651603; 23709157; 23711367; 23712977; 23740944; 23818254; 23824692; 23850724; 23868940; 23872065; 23888881; 23892590; 24015287; 24054330; 24076061; 24098051; 24099766; 24298015 nucleotide-binding oligomerization domain containing 2 Ensembl:ENSG00000167207 HGNC:5331 HPRD:05810 MIM:605956 Vega:OTTHUMG00000133171 NOD2 Bin Zhao, Yue Liu, Oliver He APG3 APG3-LIKE APG3L PC3-96 WEB: http://www.ncbi.nlm.nih.gov/gene ATG3 autophagy related 3 64422 3q13.2 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000045 (EC: ISS); GO_0000153 (EC: IPI, PMID: 11825910); GO_0005515 (EC: IPI, PMID: 11825910); GO_0005829 (EC: IDA, PMID: 11825910); GO_0006464 (EC: IDA, PMID: 11825910); GO_0006612 (EC: ISS); GO_0016567 (EC: IDA, PMID: 11825910); GO_0019776 (EC: ISS); GO_0019777 (EC: ISS); GO_0019787 (EC: IDA, PMID: 11825910); GO_0019899 (EC: IPI, PMID: 11825910); GO_0043653 (EC: ISS); GO_1902017 (EC: ISS) PMID: 11825910; 12477932; 14702039; 15144186; 15355958; 15489334; 15592455; 16303767; 16704426; 17353931; 19342671; 19838173; 19932681; 20061800; 20562859; 20697744; 20723759; 21139048; 21906983; 22053931; 22505724; 22644571; 22863883; 23119048; 23824909; 23829686; 24191030 autophagy related 3 Ensembl:ENSG00000144848 HGNC:20962 HPRD:10654 MIM:609606 Vega:OTTHUMG00000159260 ATG3 Bin Zhao, Yue Liu, Oliver He DHOF FODH MG61 PORC PPN WEB: http://www.ncbi.nlm.nih.gov/gene PORCN porcupine homolog (Drosophila) 64840 Xp11.23 20140408 9606 X protein-coding Official from a nomenclature committee GO_0009100 (EC: IEA); GO_0016055 (EC: IEA); GO_0016746 (EC: IEA); GO_0030176 (EC: IEA); GO_0032281 (EC: IEA) PMID: 10866835; 12034504; 12477932; 14702039; 15146197; 15489334; 17546030; 17546031; 18193088; 18325042; 19277062; 19309688; 19586929; 19681149; 19863546; 20198348; 20301712; 20854095; 21472892; 22509316; 22735390; 22888000; 22923569; 23131169; 23188502; 23399492; 23547709; 23696273 porcupine homolog (Drosophila) Ensembl:ENSG00000102312 HGNC:17652 HPRD:06680 MIM:300651 Vega:OTTHUMG00000024116 PORCN Bin Zhao, Yue Liu, Oliver He KRM2 WEB: http://www.ncbi.nlm.nih.gov/gene KREMEN2 kringle containing transmembrane protein 2 79412 16p13.3 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0016021 (EC: IEA); GO_0016055 (EC: IEA) PMID: 8125298; 12050670; 12477932; 14702039; 15489334; 16303743; 20846389; 21139048 kringle containing transmembrane protein 2 Ensembl:ENSG00000131650 HGNC:18797 HPRD:13933 MIM:609899 Vega:OTTHUMG00000128976 KREMEN2 Bin Zhao, Yue Liu, Oliver He APH-1B PRO1328 PSFL TAAV688 WEB: http://www.ncbi.nlm.nih.gov/gene APH1B APH1B gamma secretase subunit 83464 UNQ688/PRO1328 15q22.2 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 12297508); GO_0005886 (EC: TAS); GO_0007219 (EC: TAS); GO_0007220 (EC: TAS); GO_0008233 (EC: IDA, PMID: 12297508); GO_0016021 (EC: IDA, PMID: 12297508); GO_0016485 (EC: IDA, PMID: 12297508); GO_0030133 (EC: IDA); GO_0031293 (EC: TAS); GO_0043065 (EC: TAS); GO_0043085 (EC: IEA); GO_0048011 (EC: TAS); GO_0097190 (EC: TAS) PMID: 11076863; 11230166; 11256614; 12110170; 12297508; 12471034; 12477932; 12740439; 12763021; 12787561; 12843241; 12857757; 12975309; 14702039; 15286082; 15474363; 15489334; 15489336; 15591316; 15629423; 15721744; 15823552; 16344560; 16381901; 16630834; 16757808; 17466415; 17986144; 18987747; 19774691; 21890473; 21906983; 21963094 APH1B gamma secretase subunit Ensembl:ENSG00000138613 HGNC:24080 HPRD:06361 MIM:607630 Vega:OTTHUMG00000132863 APH1B Bin Zhao, Yue Liu, Oliver He APG10 APG10L pp12616 WEB: http://www.ncbi.nlm.nih.gov/gene ATG10 autophagy related 10 83734 PP12616 5q14.1 20140408 9606 5 protein-coding Official from a nomenclature committee GO_0005622 (EC: IDA); GO_0005737 (EC: IEA); GO_0006497 (EC: ISS); GO_0006914 (EC: IMP, PMID: 15657430); GO_0015031 (EC: IEA); GO_0019777 (EC: ISS); GO_0031401 (EC: ISS); GO_0032446 (EC: IDA, PMID: 16963840); GO_0034263 (EC: IMP, PMID: 17256008) PMID: 2890687; 8125298; 11076863; 11230166; 11256614; 12477932; 12482611; 12890687; 14702039; 15489334; 15489336; 15498874; 15657430; 16381901; 16963840; 17256008; 17353931; 20379614; 20562859; 23285162; 23850577; 24250222 autophagy related 10 Ensembl:ENSG00000152348 HGNC:20315 HPRD:16497 MIM:610800 Vega:OTTHUMG00000119041 ATG10 Bin Zhao, Yue Liu, Oliver He EIF-2A MST089 MSTP004 MSTP089 WEB: http://www.ncbi.nlm.nih.gov/gene EIF2A eukaryotic translation initiation factor 2A, 65kDa 83939 CDA02 3q25.1 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0000049 (EC: IMP, PMID: 12133843); GO_0003743 (EC: IMP, PMID: 12133843); GO_0005515 (EC: IPI, PMID: 18816594); GO_0005615 (EC: IDA); GO_0005737 (EC: IDA, PMID: 12133843); GO_0005850 (EC: IDA, PMID: 12133843); GO_0006417 (EC: IMP, PMID: 12133843); GO_0006468 (EC: IEA); GO_0009967 (EC: IEA); GO_0032933 (EC: IEA); GO_0042255 (EC: IMP, PMID: 12133843); GO_0043022 (EC: IMP, PMID: 12133843); GO_0072562 (EC: IDA) PMID: 1620067; 12133843; 12370288; 12477932; 12687390; 14702039; 15341733; 15345721; 15475356; 15718232; 15781241; 15961545; 16373505; 16631606; 16717090; 16870703; 16928686; 17274640; 17407708; 17553788; 17715234; 17894550; 18063576; 18195013; 18274552; 18287093; 18337511; 18794359; 18816594; 19131336; 19190324; 19223463; 19229320; 19586904; 19605483; 19744687; 19913121; 20376341; 20434207; 20519500; 20628086; 20706999; 21085474; 21090173; 21139048; 21203563; 21622569; 21730287; 21832049; 21906983; 21963094; 22355666; 22505724; 22863883; 22915583; 22939629; 22948139; 23000965; 23046979; 23471998; 23690448 eukaryotic translation initiation factor 2A, 65kDa Ensembl:ENSG00000144895 HGNC:3254 HPRD:11739 MIM:609234 Vega:OTTHUMG00000159775 EIF2A Bin Zhao, Yue Liu, Oliver He MOF MYST1 ZC2HC8 hMOF WEB: http://www.ncbi.nlm.nih.gov/gene KAT8 K(lysine) acetyltransferase 8 84148 PP7073 16p11.2 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0000123 (EC: IDA); GO_0000776 (EC: IEA); GO_0004402 (EC: IDA, PMID: 11742995); GO_0005515 (EC: IPI, PMID: 11965546); GO_0005634 (EC: IDA, PMID: 11742995); GO_0005654 (EC: TAS); GO_0006325 (EC: TAS); GO_0006351 (EC: IEA); GO_0008134 (EC: IDA, PMID: 11742995); GO_0016407 (EC: IDA, PMID: 11742995); GO_0016573 (EC: IDA, PMID: 11742995); GO_0019899 (EC: IEA); GO_0030099 (EC: IDA, PMID: 11742995); GO_0031965 (EC: IDA); GO_0035064 (EC: IDA, PMID: 15960975); GO_0043981 (EC: IDA); GO_0043982 (EC: IDA); GO_0043984 (EC: IDA); GO_0043984 (EC: IMP, PMID: 15960975); GO_0043995 (EC: IDA, Qualifier: contributes_to); GO_0043996 (EC: IDA, Qualifier: contributes_to); GO_0045892 (EC: IDA, PMID: 11742995); GO_0045893 (EC: IDA, PMID: 11742995); GO_0045893 (EC: IMP, PMID: 15960975); GO_0046872 (EC: IEA); GO_0046972 (EC: IDA, Qualifier: contributes_to); GO_0071339 (EC: IDA, PMID: 15960975); GO_0072487 (EC: IDA) PMID: 8125298; 10786633; 11742995; 11965546; 12397079; 12477932; 14702039; 15342556; 15489334; 15498874; 15923642; 15960975; 16024812; 16096645; 16227571; 17182677; 17189187; 17694080; 17967868; 18058815; 19578370; 19766566; 19854137; 19913121; 20018852; 20224553; 20360068; 20479123; 20628086; 21217699; 21321083; 21502975; 21691301; 22020126; 22152480; 22586264; 22918831; 22939629; 23602568; 23628702; 23638218; 23863932; 24126058; 24163370 K(lysine) acetyltransferase 8 Ensembl:ENSG00000103510 HGNC:17933 HPRD:11381 MIM:609912 Vega:OTTHUMG00000132410 KAT8 Bin Zhao, Yue Liu, Oliver He Lobe PRAS40 WEB: http://www.ncbi.nlm.nih.gov/gene AKT1S1 AKT1 substrate 1 (proline-rich) 84335 19q13.33 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 12524439); GO_0005634 (EC: IEA); GO_0005737 (EC: IDA); GO_0005829 (EC: ISS); GO_0005829 (EC: TAS); GO_0006469 (EC: IDA, PMID: 17386266); GO_0007173 (EC: TAS); GO_0008543 (EC: TAS); GO_0031931 (EC: IDA, Qualifier: colocalizes_with, PMID: 17386266); GO_0032007 (EC: IDA, PMID: 17386266); GO_0038095 (EC: TAS); GO_0043523 (EC: ISS); GO_0045087 (EC: TAS); GO_0045792 (EC: IDA, PMID: 17386266); GO_0048011 (EC: TAS); GO_0048015 (EC: TAS) PMID: 8125298; 12477932; 12524439; 14702039; 14973226; 15161933; 15302935; 15324660; 15489334; 16169070; 16174443; 16344560; 17081983; 17277771; 17386266; 17510057; 17604271; 18215133; 18372248; 19446321; 20169205; 21886838; 21900206; 21906675; 21910584; 21914810; 21981924; 22090422; 22241085; 22354785; 22863883; 22873724; 23444366; 23460019; 23712034; 24255178 AKT1 substrate 1 (proline-rich) Ensembl:ENSG00000204673 HGNC:28426 HPRD:12441 MIM:610221 Vega:OTTHUMG00000150246 AKT1S1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene DCTN5 dynactin 5 (p25) 84516 16p12.2 20140408 9606 16 protein-coding Official from a nomenclature committee GO_0000777 (EC: IEA); GO_0005813 (EC: IDA); GO_0005829 (EC: TAS); GO_0019886 (EC: TAS) PMID: 10525537; 12477932; 14702039; 15043994; 15489334; 16189514; 16344560; 17554300; 20360068; 20508983; 21139048; 21890473; 21906983; 22505724 dynactin 5 (p25) DCTN5 Bin Zhao, Yue Liu, Oliver He HUCEP-4 SCAND4 dJ874C20.4 WEB: http://www.ncbi.nlm.nih.gov/gene PGBD1 piggyBac transposable element derived 1 84547 hucep-4 6p22.1 20140408 9606 6 protein-coding Official from a nomenclature committee GO_0003700 (EC: IEA); GO_0005044 (EC: IEA); GO_0005634 (EC: IEA); GO_0016020 (EC: IEA) PMID: 8125298; 8889548; 12477932; 12955498; 16344560; 18029348; 18830724; 20534741; 20673877; 20873219; 22037552; 22488895 piggyBac transposable element derived 1 Ensembl:ENSG00000137338 HGNC:19398 HPRD:11426 Vega:OTTHUMG00000014520 PGBD1 Bin Zhao, Yue Liu, Oliver He CRACM1 IMD9 ORAT1 TMEM142A WEB: http://www.ncbi.nlm.nih.gov/gene ORAI1 ORAI calcium release-activated calcium modulator 1 84876 12q24.31 20140408 9606 12 protein-coding Official from a nomenclature committee GO_0002115 (EC: IEA); GO_0002376 (EC: IEA); GO_0005515 (EC: IPI, PMID: 17905723); GO_0005887 (EC: IDA, PMID: 16645049); GO_0007596 (EC: TAS); GO_0015279 (EC: IDA, PMID: 16645049); GO_0043234 (EC: IEA); GO_0051924 (EC: IMP, PMID: 16921383); GO_0051928 (EC: IDA, PMID: 16645049) PMID: 12477932; 14702039; 15489334; 16147976; 16341674; 16582901; 16645049; 16733527; 16766533; 16807233; 16921383; 16978865; 17045966; 17218358; 17224452; 17360584; 17400243; 17442569; 17452328; 17684017; 17702753; 17905723; 17968026; 17991693; 18006576; 18096706; 18187424; 18190941; 18239188; 18250319; 18326500; 18400989; 18403424; 18420579; 18436303; 18448669; 18506892; 18542992; 18569867; 18644792; 18768920; 18832420; 18843204; 18845811; 18995841; 19075015; 19088073; 19171672; 19182790; 19185847; 19189966; 19228695; 19249086; 19260825; 19289460; 19366689; 19403622; 19429662; 19433061; 19447651; 19487696; 19506081; 19622747; 19675303; 19706554; 19754898; 19843011; 19887627; 19965684; 20004786; 20007711; 20018736; 20037597; 20073506; 20194530; 20194792; 20354224; 20395295; 20534587; 20587595; 20607548; 20887894; 20961852; 21224390; 21239714; 21266088; 21300876; 21321120; 21364678; 21383014; 21408196; 21420116; 21441136; 21487896; 21640715; 21670147; 21674042; 21782006; 21790973; 21847095; 21865174; 21873556; 21945734; 21956116; 21987804; 22031597; 22110130; 22144678; 22253717; 22278058; 22298778; 22381755; 22384096; 22387225; 22389502; 22494970; 22495877; 22546867; 22549787; 22556336; 22586105; 22640869; 22641696; 22681560; 22778704; 23043102; 23049826; 23115638; 23184982; 23203806; 23212906; 23307288; 23447534; 23455504; 23512987; 23512989; 23515871; 23685155; 23700407; 23703676; 23774210; 23800047; 23816623; 23890116; 23890117; 23943619; 24056904; 24321771 ORAI calcium release-activated calcium modulator 1 HGNC:25896 HPRD:08599 MIM:610277 ORAI1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene WNT3A wingless-type MMTV integration site family, member 3A 89780 1q42 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0001649 (EC: IEA); GO_0001701 (EC: IEA); GO_0001934 (EC: IDA); GO_0001947 (EC: IEA); GO_0002092 (EC: IDA, PMID: 16890161); GO_0003136 (EC: IDA, PMID: 19736317); GO_0003713 (EC: ISS); GO_0005109 (EC: IBA); GO_0005110 (EC: IEA); GO_0005515 (EC: IPI, PMID: 19072540); GO_0005576 (EC: TAS); GO_0005578 (EC: IEA); GO_0005615 (EC: IBA); GO_0005615 (EC: ISS); GO_0005788 (EC: TAS); GO_0005796 (EC: TAS); GO_0005886 (EC: TAS); GO_0007411 (EC: IEA); GO_0008284 (EC: ISS); GO_0009986 (EC: ISS); GO_0010387 (EC: ISS); GO_0010977 (EC: ISS); GO_0019904 (EC: IEA); GO_0021527 (EC: IEA); GO_0021766 (EC: IEA); GO_0021846 (EC: ISS); GO_0021874 (EC: IEA); GO_0021904 (EC: IEA); GO_0030097 (EC: IEA); GO_0030182 (EC: IBA); GO_0030182 (EC: ISS); GO_0030198 (EC: IEA); GO_0030879 (EC: IEA); GO_0030890 (EC: IEA); GO_0032092 (EC: IDA, PMID: 16890161); GO_0033138 (EC: IDA); GO_0034613 (EC: IEA); GO_0035413 (EC: IDA); GO_0035914 (EC: IEA); GO_0036342 (EC: IEA); GO_0042472 (EC: IEA); GO_0043280 (EC: IEA); GO_0045599 (EC: IEA); GO_0045893 (EC: ISS); GO_0045944 (EC: IDA); GO_0048018 (EC: IDA); GO_0048337 (EC: IDA); GO_0048343 (EC: IEA); GO_0048697 (EC: IEA); GO_0048843 (EC: IEA); GO_0050768 (EC: ISS); GO_0051091 (EC: IEA); GO_0060021 (EC: IMP, PMID: 18413325); GO_0060070 (EC: IDA, PMID: 19101069); GO_0061098 (EC: IEA); GO_0061184 (EC: IDA, PMID: 10654605); GO_0061317 (EC: IDA); GO_0070507 (EC: IEA); GO_0070527 (EC: IEA); GO_0071300 (EC: ISS); GO_0090245 (EC: IEA); GO_0090263 (EC: IDA, PMID: 17976063); GO_2000049 (EC: IEA); GO_2000081 (EC: IEA); GO_2000727 (EC: IDA) PMID: 8167409; 8168088; 10557084; 10654605; 10866835; 11414706; 11788904; 11836627; 12052822; 12067714; 12477932; 12556519; 12629517; 12805222; 12897152; 14702039; 14722104; 14739301; 15454084; 15489334; 16227623; 16344560; 16565323; 16621789; 16710414; 16799642; 16890161; 17137849; 17211448; 17458904; 17544413; 17546602; 17595165; 17698587; 17822920; 17888180; 17976063; 17990294; 18242164; 18305214; 18344425; 18413325; 18462958; 18505824; 18555765; 18615587; 18632632; 18719101; 18724388; 18941195; 19072540; 19101069; 19144919; 19265664; 19351711; 19453261; 19523451; 19736317; 19816934; 19881541; 19887570; 19901330; 19910923; 20085589; 20093360; 20227366; 20336604; 20347274; 20634891; 20693288; 20723538; 20735988; 20932509; 21123170; 21422228; 21536751; 21600099; 21606194; 21667018; 21670201; 21957254; 22005028; 22110662; 22396540; 22550094; 22705156; 22714865; 22789636; 22824791; 22876125; 22941468; 23168335; 23204070; 23268410; 23276938; 23337036; 23382209; 23396967; 23396968; 23509994; 23559372; 23893409; 23954131; 23999248; 24321072 wingless-type MMTV integration site family, member 3A WNT3A Bin Zhao, Yue Liu, Oliver He CHRNA7 CHRNA7-DR1 D-10 WEB: http://www.ncbi.nlm.nih.gov/gene CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 89832 15q13.1 20140408 9606 15 protein-coding Official from a nomenclature committee GO_0005230 (EC: IEA); GO_0016021 (EC: IEA) PMID: 9782083; 11424985; 11829490; 12477932; 14729617; 15489334; 15885267; 16417613; 16572171; 16823804; 17012698; 17192894; 19082523; 19149910; 19462340; 19631623; 19641318; 20351714; 20926142; 22300029; 23553139; 24024466 CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion Ensembl:ENSG00000166664 HGNC:15781 HPRD:18704 MIM:609756 Vega:OTTHUMG00000175645 CHRFAM7A Bin Zhao, Yue Liu, Oliver He XTP7 WEB: http://www.ncbi.nlm.nih.gov/gene EXOC3L2 exocyst complex component 3-like 2 90332 19q13.32 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000145 (EC: IEA); GO_0003674 (EC: ND); GO_0005575 (EC: ND); GO_0006887 (EC: IEA); GO_0008150 (EC: ND) PMID: 8125298; 8889549; 12477932; 14702039; 19197348; 20460622; 21566143; 22139419; 22381399 exocyst complex component 3-like 2 Ensembl:ENSG00000130201 HGNC:30162 HPRD:10311 Vega:OTTHUMG00000155018 EXOC3L2 Bin Zhao, Yue Liu, Oliver He C9orf26 DVS27 IL1F11 NF-HEV NFEHEV WEB: http://www.ncbi.nlm.nih.gov/gene IL33 interleukin 33 90865 RP11-575C20.2 9p24.1 20140408 9606 9 protein-coding Official from a nomenclature committee GO_0002686 (EC: IEA); GO_0002826 (EC: IEA); GO_0002830 (EC: IEA); GO_0005125 (EC: IDA, PMID: 19841166); GO_0005515 (EC: IPI, PMID: 16286016); GO_0005615 (EC: IEA); GO_0005634 (EC: IEA); GO_0005694 (EC: IEA); GO_0006351 (EC: IEA); GO_0030133 (EC: IEA); GO_0032689 (EC: IEA); GO_0032736 (EC: IEA); GO_0032753 (EC: IEA); GO_0032754 (EC: IEA); GO_0032755 (EC: IEA); GO_0043032 (EC: IDA, PMID: 19841166); GO_0045944 (EC: ISS, PMID: 19841166); GO_0050729 (EC: ISS, PMID: 19841166); GO_0051024 (EC: IEA); GO_0051025 (EC: IEA); GO_0090197 (EC: IDA, PMID: 19841166) PMID: 10566975; 12477932; 12819012; 15164053; 15489334; 16169070; 16286016; 17185418; 17623648; 17675461; 17700564; 17853410; 18250453; 18539196; 18688256; 18762778; 18787100; 18802081; 18827826; 18836528; 18941187; 18955562; 19037964; 19198610; 19204726; 19248109; 19266498; 19372185; 19393621; 19439663; 19465481; 19508382; 19559631; 19596270; 19756962; 19801525; 19841166; 19860791; 19888696; 19906013; 19913053; 19918048; 20029461; 20035719; 20072851; 20153038; 20305685; 20338108; 20379614; 20385815; 20405148; 20406635; 20532808; 20534741; 20682660; 20689058; 20708824; 20731692; 20816195; 20860503; 20926795; 20931364; 20958987; 20963466; 21037074; 21190867; 21246230; 21357533; 21431944; 21441054; 21454686; 21519352; 21674220; 21674479; 21682736; 21684348; 21734074; 21737781; 21765905; 21802127; 21804549; 21898270; 21935266; 21949719; 22079334; 22100205; 22189043; 22215666; 22233535; 22239947; 22246057; 22270365; 22304300; 22307629; 22315510; 22329990; 22349136; 22540331; 22587998; 22590860; 22627366; 22634619; 22673732; 22682001; 22699663; 22708120; 22785132; 22809957; 22819319; 22828942; 22836779; 22841163; 22858587; 22921786; 23000728; 23028054; 23039129; 23093619; 23159404; 23162017; 23178147; 23205532; 23206447; 23219168; 23261461; 23300625; 23319592; 23357301; 23362867; 23363980; 23433789; 23464866; 23472165; 23484079; 23485578; 23488689; 23521712; 23525523; 23585867; 23634226; 23641786; 23656573; 23725175; 23759184; 23764374; 23775566; 23805875; 23817569; 23855553; 23935505; 23936781; 23980170; 23999434; 24075188; 24106520; 24107076; 24116703; 24257755; 24323357; 24459820 interleukin 33 Ensembl:ENSG00000137033 HGNC:16028 HPRD:12275 MIM:608678 Vega:OTTHUMG00000019516 IL33 Bin Zhao, Yue Liu, Oliver He AGTAVPRL AII AVP C1orf7 CIAS1 CLR1.1 FCAS FCU MWS NALP3 PYPAF1 WEB: http://www.ncbi.nlm.nih.gov/gene NLRP3 NLR family, pyrin domain containing 3 114548 1q44 20140408 9606 1 protein-coding Official from a nomenclature committee GO_0002674 (EC: IMP, PMID: 11687797); GO_0005515 (EC: IPI, PMID: 11786556); GO_0005524 (EC: IEA); GO_0005737 (EC: IDA, PMID: 17164409); GO_0005737 (EC: TAS, PMID: 15967716); GO_0005829 (EC: TAS); GO_0006915 (EC: NAS, PMID: 12032915); GO_0006919 (EC: IEA); GO_0006952 (EC: TAS, PMID: 15967716); GO_0006954 (EC: IMP, PMID: 12093792); GO_0007165 (EC: NAS, PMID: 11786556); GO_0009595 (EC: TAS, PMID: 15967716); GO_0032088 (EC: IDA, PMID: 14662828); GO_0032611 (EC: IEA); GO_0032621 (EC: IEA); GO_0035872 (EC: TAS); GO_0042347 (EC: IDA, PMID: 14662828); GO_0042834 (EC: TAS, PMID: 15967716); GO_0043280 (EC: IDA, PMID: 15030775); GO_0044546 (EC: IEA); GO_0045087 (EC: TAS); GO_0050701 (EC: IEA); GO_0050713 (EC: IMP, PMID: 12483741); GO_0050718 (EC: IDA, PMID: 15030775); GO_0050728 (EC: IMP, PMID: 12483741); GO_0051092 (EC: IDA, PMID: 19158675); GO_0051259 (EC: TAS, PMID: 15967716); GO_0051607 (EC: IEA); GO_0071222 (EC: IMP, PMID: 12483741); GO_0072559 (EC: IDA, PMID: 15030775) PMID: 9653160; 10741953; 11042152; 11687797; 11786556; 11967258; 11992256; 12032915; 12093792; 12355493; 12477932; 12483741; 12522564; 12563287; 12615073; 12673085; 12766759; 14630794; 14662828; 15020601; 15030775; 15071491; 15107016; 15334500; 15593220; 15967716; 16037825; 16234278; 16344560; 16531551; 16642435; 16710414; 16868559; 17046979; 17164343; 17164409; 17178985; 17213252; 17284928; 17393462; 17435760; 17592301; 17599094; 17620097; 17697637; 17763411; 17907925; 18005730; 18063752; 18080732; 18084703; 18174231; 18175851; 18189199; 18263599; 18311798; 18576390; 18719602; 18772453; 19001869; 19058789; 19098911; 19120479; 19120481; 19158675; 19201894; 19223160; 19254587; 19319132; 19337385; 19364881; 19414800; 19454352; 19570822; 19579027; 19648107; 19767079; 19784369; 19805629; 19811501; 19824913; 19826485; 19890791; 19913121; 20002790; 20008285; 20011700; 20031576; 20038581; 20060594; 20131254; 20131270; 20135584; 20148899; 20179743; 20182451; 20237496; 20368800; 20370570; 20384614; 20401456; 20401526; 20403135; 20407038; 20421639; 20502346; 20506209; 20628086; 20668705; 20688930; 20800603; 20808838; 20884650; 20962258; 20980503; 21035374; 21051542; 21058222; 21109514; 21124315; 21124859; 21217695; 21241317; 21245836; 21300955; 21315400; 21342182; 21394384; 21421008; 21451572; 21508263; 21550598; 21560198; 21566220; 21621776; 21637346; 21646297; 21876553; 21880711; 21930705; 21940629; 21940680; 21971358; 21978001; 21994456; 22102247; 22112657; 22128899; 22146561; 22227418; 22227487; 22276187; 22295065; 22325453; 22403613; 22461501; 22490866; 22497426; 22503597; 22522430; 22524199; 22529966; 22541070; 22558425; 22608495; 22698681; 22723549; 22768094; 22796220; 22843550; 22904305; 22933232; 22933241; 22935299; 22948162; 22981536; 22984081; 22984082; 22997256; 23015306; 23066025; 23086037; 23110140; 23171454; 23206693; 23209696; 23211828; 23221073; 23254930; 23264657; 23271661; 23280543; 23315075; 23375846; 23382313; 23399110; 23427152; 23430110; 23434541; 23440695; 23505242; 23530046; 23549611; 23563199; 23567555; 23582325; 23588528; 23614732; 23633957; 23737748; 23738518; 23815151; 23825667; 23838163; 23840644; 23843215; 23871209; 23884315; 23911403; 23937860; 23954133; 23969696; 23973727; 23980097; 24008734; 24048902; 24144834; 24166187 NLR family, pyrin domain containing 3 Ensembl:ENSG00000162711 HGNC:16400 HPRD:05915 MIM:606416 Vega:OTTHUMG00000040647 NLRP3 Bin Zhao, Yue Liu, Oliver He hSorCS WEB: http://www.ncbi.nlm.nih.gov/gene SORCS1 sortilin-related VPS10 domain containing receptor 1 114815 RP11-446H13.1 10q23-q25 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0005515 (EC: IPI, PMID: 12482870); GO_0007218 (EC: NAS, PMID: 11499680); GO_0008188 (EC: NAS, PMID: 11499680); GO_0016020 (EC: IDA, PMID: 12482870); GO_0016021 (EC: IEA) PMID: 11499680; 12477932; 12482870; 14702039; 15164054; 16385451; 18315530; 18519826; 18830724; 19241460; 19875614; 19913121; 19948975; 20379614; 20413850; 20534741; 20574532; 20628086; 20677014; 20881129; 21294870; 22046233; 22353753; 23055476; 23279143; 23472165; 23700427; 23780848; 23934736; 24128306 sortilin-related VPS10 domain containing receptor 1 Ensembl:ENSG00000108018 HGNC:16697 HPRD:12098 MIM:606283 Vega:OTTHUMG00000019018 SORCS1 Bin Zhao, Yue Liu, Oliver He HAK WEB: http://www.ncbi.nlm.nih.gov/gene ALPK2 alpha-kinase 2 115701 18q21.31 20140408 9606 18 protein-coding Official from a nomenclature committee GO_0004674 (EC: IEA); GO_0005524 (EC: IEA); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT) PMID: 10021370; 14702039; 19690890; 21833088; 21963094; 22641666 alpha-kinase 2 Ensembl:ENSG00000198796 HGNC:20565 HPRD:11019 Vega:OTTHUMG00000132755 ALPK2 Bin Zhao, Yue Liu, Oliver He MIST WEB: http://www.ncbi.nlm.nih.gov/gene CLNK cytokine-dependent hematopoietic cell linker 116449 4p16.1 20140408 9606 4 protein-coding Official from a nomenclature committee GO_0005070 (EC: NAS, PMID: 10744659); GO_0005515 (EC: IPI, PMID: 16273093); GO_0005622 (EC: NAS, PMID: 10744659); GO_0006955 (EC: NAS, PMID: 10744659); GO_0007169 (EC: IEA); GO_0009967 (EC: NAS, PMID: 10744659); GO_0035556 (EC: IDA, PMID: 10744659) PMID: 10562326; 10744659; 11463797; 12477932; 14702039; 16273093; 18987618; 20379614; 22561518 cytokine-dependent hematopoietic cell linker HGNC:17438 HPRD:14720 MIM:611434 CLNK Bin Zhao, Yue Liu, Oliver He NCKX4 SHEP6 SLC24A2 WEB: http://www.ncbi.nlm.nih.gov/gene SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 123041 14q32.12 20140408 9606 14 protein-coding Official from a nomenclature committee GO_0005886 (EC: TAS); GO_0006811 (EC: TAS); GO_0006874 (EC: IEA); GO_0007608 (EC: ISS); GO_0008273 (EC: IEA); GO_0015293 (EC: IEA); GO_0016021 (EC: IEA); GO_0050896 (EC: IEA); GO_0055085 (EC: TAS); GO_0097186 (EC: ISS) PMID: 12379639; 12477932; 14702039; 15489334; 17952075; 18483556; 19609347; 19710684; 20379614; 20585627; 21126331; 21546767; 23375655; 23548203 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 HGNC:10978 HPRD:15353 MIM:609840 SLC24A4 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 245802 11q12.2 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0016021 (EC: IEA) PMID: 11486273; 12477932; 15489334; 17207965; 21460841 membrane-spanning 4-domains, subfamily A, member 6E MS4A6E Bin Zhao, Yue Liu, Oliver He FAM26C WEB: http://www.ncbi.nlm.nih.gov/gene CALHM1 calcium homeostasis modulator 1 255022 10q24.33 20140408 9606 10 protein-coding Official from a nomenclature committee GO_0005227 (EC: IDA); GO_0005244 (EC: IDA); GO_0005262 (EC: IEA); GO_0005789 (EC: IEA); GO_0005887 (EC: IDA); GO_0006812 (EC: IDA); GO_0015867 (EC: ISS); GO_0034765 (EC: IDA); GO_0042802 (EC: IPI, PMID: 18585350); GO_0050913 (EC: ISS); GO_0050916 (EC: ISS); GO_0050917 (EC: ISS); GO_0051260 (EC: IDA) PMID: 12477932; 15164054; 15489334; 18585350; 18667147; 19038093; 19070563; 19191331; 19191332; 19472444; 19545933; 19655363; 19944073; 20005921; 20061624; 20164573; 20164592; 20164602; 20534741; 20574532; 20592574; 20634593; 20847397; 21378601; 21439911; 21574960; 21629967; 22874670; 23300080; 23345406; 23467090; 23884934; 23974872 calcium homeostasis modulator 1 Ensembl:ENSG00000185933 HGNC:23494 HPRD:16879 MIM:612234 Vega:OTTHUMG00000018991 CALHM1 Bin Zhao, Yue Liu, Oliver He HLA-17 WEB: http://www.ncbi.nlm.nih.gov/gene HLA-S major histocompatibility complex, class I, S (pseudogene) 267015 6p21.3 20140408 9606 6 pseudo Official from a nomenclature committee PMID: 1517563; 10452889 major histocompatibility complex, class I, S (pseudogene) HGNC:19395 HLA-S Bin Zhao, Yue Liu, Oliver He DUB-3 DUB3 USP17 WEB: http://www.ncbi.nlm.nih.gov/gene USP17L2 ubiquitin specific peptidase 17-like family member 2 377630 8p23.1 20140408 9606 8 protein-coding Official from a nomenclature committee GO_0000075 (EC: IMP); GO_0004221 (EC: IMP); GO_0004843 (EC: IDA); GO_0004843 (EC: IMP, PMID: 19188362); GO_0005515 (EC: IPI); GO_0005634 (EC: IDA); GO_0005789 (EC: IDA, PMID: 19188362); GO_0006511 (EC: IEA); GO_0006915 (EC: IEA); GO_0007093 (EC: IMP); GO_0010955 (EC: IMP, PMID: 19188362); GO_0016579 (EC: IDA); GO_0030334 (EC: IMP); GO_0031064 (EC: IMP); GO_0032321 (EC: IMP); GO_0034261 (EC: IDA, PMID: 19188362); GO_0042127 (EC: IMP, PMID: 19188362); GO_0042981 (EC: IMP); GO_0050691 (EC: IMP); GO_0070536 (EC: IDA); GO_0070536 (EC: IMP, PMID: 19188362); GO_0071108 (EC: IMP, PMID: 19188362); GO_0071586 (EC: IMP, PMID: 19188362); GO_0090315 (EC: IMP, PMID: 19188362); GO_1900027 (EC: IMP); GO_1900245 (EC: IMP); GO_1900246 (EC: IMP) PMID: 9806828; 10936051; 11941478; 14699124; 15780755; 16611142; 17109758; 19188362; 19615732; 19718026; 20147298; 20228807; 20228808; 20368735; 20388806; 20403174; 20715989; 21239494; 21448158 ubiquitin specific peptidase 17-like family member 2 Ensembl:ENSG00000223443 HGNC:34434 HPRD:16844 MIM:610186 Vega:OTTHUMG00000165295 USP17L2 Bin Zhao, Yue Liu, Oliver He MIR128A MIRN128-1 MIRN128A WEB: http://www.ncbi.nlm.nih.gov/gene MIR128-1 microRNA 128-1 406915 2q21.3 20140408 9606 2 ncRNA Official from a nomenclature committee PMID: 12007417; 15325244; 16381832; 17604727; 18056805; 18381601; 19048628; 19713529; 19955085; 20054641; 20889907; 21228036; 21358821; 21596314; 22614013; 23034410; 23482671; 23492773; 23958464 microRNA 128-1 HGNC:31510 MIM:611774 miRBase:MI0000447 MIR128-1 Bin Zhao, Yue Liu, Oliver He CC-CKR-2 CCR-2 CCR2A CCR2B CD192 CKR2 CKR2A CKR2B CMKBR2 MCP-1-R WEB: http://www.ncbi.nlm.nih.gov/gene CCR2 chemokine (C-C motif) receptor 2 729230 hCG_14621 3p21.31 20140408 9606 3 protein-coding Official from a nomenclature committee GO_0001974 (EC: ISS); GO_0002407 (EC: TAS, PMID: 16621978); GO_0002827 (EC: ISS); GO_0002829 (EC: ISS); GO_0004950 (EC: TAS, PMID: 10623817); GO_0005737 (EC: IDA, PMID: 15995708); GO_0005829 (EC: ISS); GO_0005886 (EC: IDA, PMID: 15995708); GO_0005886 (EC: TAS); GO_0005887 (EC: TAS, PMID: 8146186); GO_0006874 (EC: ISS); GO_0006935 (EC: TAS, PMID: 10623817); GO_0006954 (EC: IEA); GO_0006955 (EC: TAS, PMID: 10751368); GO_0006968 (EC: TAS, PMID: 10201901); GO_0007194 (EC: TAS, PMID: 8995400); GO_0007204 (EC: TAS, PMID: 9548499); GO_0007259 (EC: TAS, PMID: 9670957); GO_0009611 (EC: TAS, PMID: 8146186); GO_0010574 (EC: ISS); GO_0010820 (EC: ISS); GO_0016021 (EC: TAS, PMID: 8530354); GO_0016032 (EC: IEA); GO_0016493 (EC: IEA); GO_0016525 (EC: ISS); GO_0019221 (EC: IDA, PMID: 15995708); GO_0019725 (EC: ISS); GO_0030425 (EC: ISS); GO_0031727 (EC: IDA, PMID: 15995708); GO_0032729 (EC: ISS); GO_0032743 (EC: ISS); GO_0035705 (EC: ISS); GO_0042535 (EC: ISS); GO_0042803 (EC: ISS); GO_0043025 (EC: ISS); GO_0043204 (EC: ISS); GO_0043310 (EC: ISS); GO_0045087 (EC: TAS); GO_0046641 (EC: ISS); GO_0048471 (EC: ISS); GO_0050729 (EC: ISS); GO_0050870 (EC: ISS); GO_0070098 (EC: ISS); GO_0090026 (EC: IDA, PMID: 18587271); GO_0090026 (EC: ISS); GO_0090265 (EC: ISS); GO_2000439 (EC: ISS); GO_2000451 (EC: ISS); GO_2000464 (EC: IDA, PMID: 12271471); GO_2000473 (EC: ISS) PMID: 2834384; 8048929; 8146186; 8530354; 8884276; 8995400; 9058802; 9115216; 9143512; 9195948; 9225989; 9252328; 9287323; 9501202; 9548499; 9653051; 9662369; 9670957; 9710230; 9736741; 9789057; 9886417; 10201901; 10479649; 10486323; 10529171; 10623817; 10741397; 10751368; 10877489; 10888629; 10985245; 11023492; 11046064; 11115360; 11120855; 11175286; 11181995; 11264152; 11350939; 11377705; 11385319; 11468722; 11470772; 11477473; 11485615; 11500196; 11590385; 11596075; 11694103; 11696224; 11709782; 11729511; 11752157; 11756347; 11779135; 11782014; 11804551; 11856781; 11860793; 11860823; 11873083; 11898620; 11958683; 11964548; 11988632; 12001056; 12010355; 12032878; 12070001; 12078856; 12079277; 12082592; 12149192; 12192431; 12201365; 12215924; 12239249; 12271471; 12374865; 12399623; 12403355; 12426226; 12436194; 12445801; 12447757; 12469616; 12477932; 12556692; 12557141; 12571520; 12584049; 12651900; 12654703; 12680626; 12719858; 12837756; 12853162; 12853745; 12882757; 12884524; 12889997; 12913933; 13678532; 14533004; 14533983; 14624371; 14644039; 14647058; 14742283; 14981141; 15053339; 15076247; 15086346; 15086398; 15135805; 15140377; 15192276; 15230854; 15236615; 15257681; 15319853; 15362666; 15458467; 15465089; 15466648; 15472820; 15488313; 15489334; 15575507; 15579296; 15585333; 15602133; 15611878; 15639953; 15721423; 15750046; 15754978; 15769362; 15793370; 15863470; 15929697; 15976001; 15980693; 15992849; 15995708; 16033640; 16055130; 16095529; 16123688; 16140745; 16196460; 16206074; 16207551; 16261210; 16286054; 16286055; 16305685; 16314800; 16320328; 16323127; 16344560; 16356504; 16415174; 16426243; 16461193; 16478397; 16480760; 16485782; 16524739; 16529059; 16598837; 16621978; 16631114; 16641997; 16733654; 16781696; 16831471; 16858645; 16865553; 16903979; 16908772; 16950632; 17060059; 17091019; 17094383; 17135764; 17216598; 17240189; 17295203; 17298432; 17355643; 17361671; 17364026; 17395051; 17413295; 17417600; 17426779; 17428349; 17464174; 17465499; 17482150; 17499741; 17504503; 17558413; 17560067; 17596666; 17604544; 17615573; 17653321; 17664883; 17672867; 17688234; 17703277; 17703412; 17704101; 17715128; 17786209; 17845302; 17917677; 17934338; 17989610; 18055544; 18060801; 18093816; 18096169; 18164016; 18172114; 18186797; 18197127; 18240029; 18306985; 18332000; 18391751; 18513341; 18577758; 18587271; 18615095; 18633131; 18676680; 18763111; 18829011; 18845960; 18846510; 18855658; 18928397; 18936436; 18974840; 18977759; 18996288; 19002595; 19017998; 19028820; 19032065; 19037908; 19055601; 19064579; 19082218; 19098363; 19124913; 19131662; 19170196; 19196047; 19225544; 19258923; 19263529; 19411748; 19420105; 19433914; 19465829; 19479237; 19506371; 19520154; 19526283; 19527467; 19535619; 19559392; 19578796; 19625176; 19643177; 19669591; 19692168; 19693089; 19720836; 19841162; 19904283; 19917610; 19942750; 19950235; 19958843; 19965779; 20017911; 20038229; 20066125; 20153665; 20181074; 20182805; 20190752; 20220260; 20231199; 20339010; 20364004; 20380698; 20411675; 20442634; 20449800; 20452482; 20483750; 20485444; 20503287; 20531015; 20536507; 20537184; 20603037; 20605053; 20628649; 20637631; 20673868; 20681057; 20726788; 20740585; 20808917; 20842059; 20947712; 21054877; 21091093; 21097527; 21097672; 21146687; 21148810; 21220372; 21264360; 21322034; 21348591; 21396623; 21429204; 21440726; 21450101; 21461583; 21527853; 21570337; 21602126; 21667221; 21682549; 21868018; 21883707; 21890375; 22026334; 22041342; 22081934; 22086059; 22159219; 22183310; 22197827; 22218121; 22226505; 22276574; 22285384; 22479344; 22554651; 22607625; 22612293; 22615942; 22685564; 22752804; 22815949; 22842622; 22909007; 22927430; 23007133; 23041556; 23057571; 23090289; 23185481; 23185512; 23251661; 23298254; 23325742; 23374597; 23376609; 23408426; 23454776; 23612252; 23632061; 23657965; 23686489; 23880174; 24078580; 24128342 chemokine (C-C motif) receptor 2 Ensembl:ENSG00000121807 HGNC:1603 MIM:601267 Vega:OTTHUMG00000156466 CCR2 Bin Zhao, Yue Liu, Oliver He GATAD3 GLP-1 GLP1 WEB: http://www.ncbi.nlm.nih.gov/gene ZGLP1 zinc finger, GATA-like protein 1 100125288 19p13.2 20140408 9606 19 protein-coding Official from a nomenclature committee GO_0000122 (EC: IEA); GO_0003700 (EC: IEA); GO_0005634 (EC: IEA); GO_0006351 (EC: IEA); GO_0007275 (EC: IEA); GO_0007283 (EC: IEA); GO_0008270 (EC: IEA); GO_0043565 (EC: IEA); GO_0048599 (EC: IEA) PMID: 12477932; 14702039; 15057824; 15489334; 16982049 zinc finger, GATA-like protein 1 Ensembl:ENSG00000220201 HGNC:37245 MIM:611639 Vega:OTTHUMG00000152114 ZGLP1 Bin Zhao, Yue Liu, Oliver He WEB: http://www.ncbi.nlm.nih.gov/gene 100271696 1p36 20140305 9606 1 unknown NCBI-supplied Multiple sclerosis, susceptiblity to, 4 MS4 Bin Zhao, Yue Liu, Oliver He CASP-12 CASP12P1 WEB: http://www.ncbi.nlm.nih.gov/gene CASP12 caspase 12 (gene/pseudogene) 100506742 UNQ9415 11q22.3 20140408 9606 11 protein-coding Official from a nomenclature committee GO_0004197 (EC: IBA); GO_0005737 (EC: IBA); GO_0030968 (EC: IEA); GO_0042981 (EC: IEA); GO_0050727 (EC: IBA, Qualifier: NOT); GO_0070059 (EC: IBA); GO_0072557 (EC: IBA, Qualifier: NOT); GO_0072559 (EC: IBA, Qualifier: NOT); GO_0097169 (EC: IBA, Qualifier: NOT); GO_0097194 (EC: IBA, Qualifier: NOT) PMID: 9038361; 11278723; 11329013; 11943137; 12054529; 12975309; 14532116; 15033764; 15129283; 16532395; 16917906; 17574210; 18329614; 18332441; 18710920; 18791174; 19447924; 19721713; 20031604; 20041182; 20299359; 20299368; 20423816; 20577092; 20646990; 21706251; 21872999 caspase 12 (gene/pseudogene) Ensembl:ENSG00000204403 HGNC:19004 MIM:608633 Vega:OTTHUMG00000154965 CASP12 Bin Zhao, Yue Liu, Oliver He lincRNA-RoR WEB: http://www.ncbi.nlm.nih.gov/gene LINC-ROR long intergenic non-protein coding RNA, regulator of reprogramming 100885779 18q21.31 20140408 9606 18 ncRNA Official from a nomenclature committee PMID: 21057500; 23208419; 23541921; 23597480; 24463816 long intergenic non-protein coding RNA, regulator of reprogramming Ensembl:ENSG00000258609 HGNC:43773 MIM:615173 LINC-ROR A representation that is either the output of a clinical history taking or a physical examination or an image finding, or some combination thereof. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-07-19T10:18:02Z clinical finding A series of statements representing health-relevant qualities of a patient and of a patient's family. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-07-19T10:18:59Z clinical history A representation of a quality of a specimen that is the output of a laboratory test and that can support an inference to an assertion about some quality of the patient. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T10:21:58Z laboratory finding A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-07-19T11:13:49Z phenotype A quality of a patient, a material entity that is part of a patient, or a processual entity that a patient participates in, any one of which is observed in a physical examination and is deemed by the clinician to be of clinical significance. note: defined class Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-11-18T11:14:36Z sign A physical sign in which a non-zero value is standardly considered to be an indication that the organism is alive. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:19:17Z vital sign A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:21:20Z disease http://purl.obolibrary.org/obo/DOID_4 Homeostasis is defined as the property of a system in which variables are regulated so that internal conditions remain stable and relatively constant. Examples of homeostasis include the regulation of body temperature, and the balance between acidity and alkalinity. It is a process that maintains the stability of the organism’s internal environment in response to fluctuations in external environmental conditions. Albert Goldfain creation date: 2009-06-23T11:22:01Z homeostasis Homeostasis is defined as the property of a system in which variables are regulated so that internal conditions remain stable and relatively constant. Examples of homeostasis include the regulation of body temperature, and the balance between acidity and alkalinity. It is a process that maintains the stability of the organism’s internal environment in response to fluctuations in external environmental conditions. https://www.ncbi.nlm.nih.gov/pubmed/26389962 Homeostasis that is clinically abnormal for an organism of a given type and age in a given environment. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:26:44Z abnormal homeostasis A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:39:44Z disorder A sequence of acts of observing and measuring qualities of a patient performed by a clinician; measurements may occur with and without elicitation. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-07-19T11:50:18Z physical examination A process in which at least one bodily component of an organsim participates. Albert Goldfain http://www.jbiomedsem.com/content/1/1/10 creation date: 2009-06-23T11:53:49Z From OGMS: http://purl.obolibrary.org/obo/OGMS_0000060 bodily process A bodily process that is clinically abnormal. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:54:29Z pathological bodily process The representation of a conclusion of a diagnostic process. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T12:42:23Z diagnosis TODO: Define. The information regarding anatomic findings obtained through the use of observation, palpation, percussion, and auscultation. Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=26 creation date: 2009-11-24T04:51:11Z Modified definition physical examination finding https://www.ncbi.nlm.nih.gov/books/NBK361/ A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate the signs and symptoms of a disorder or pathological process Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=35 creation date: 2010-03-31T04:51:11Z treatment A bodily process caused by some disorder that results in recruitment of leukocytes into a localized tissue site, typically causing localized pain and swelling. Albert Goldfain Richard Scheuermann Sagar Jain http://code.google.com/p/ogms/wiki/Meeting_notes_20100513 creation date: 2010-07-19T11:57:44Z Updated: 10 NOV 2015 inflammatory process A planned process with the objective to improve the health status of a patient that directly involves the treatment, diagnosis, or prevention of disease or injury of a patient Albert Goldfain Sagar Jain http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6 creation date: 2011-02-21T09:57:44Z editor date: 2017-04-18 creation date: 2011-02-21T09:57:44Z editor date: 2017-04-18 health care process A treatment whose completion is hypothesized by a health care provider to eliminate a disorder or to alleviate the signs and symptoms of a disorder or pathological process. Creation data: 2018-11-27 therapeutic procedure A disease stage that marks the beginning of a disease creation date 2018-11-27 onset a data item that is about a patient and is the specified output of a health care process assay or diagnostic process creation date: 2018-11-27 clinical data item A study design that is multidisciplinary done at the population level or among the population groups, generally to find the cause, incidence or spread of the disease or to see the response to the treatment, nutrition or environment. Alice Nzinga population based study design Pathogen-Associated Molecular Pattern Molecules Adenine Nucleotides Adenosine Diphosphate Adenosine Monophosphate Blood Proteins Cell Cycle Cholinesterase Inhibitors Chylomicrons Diagnosis, Differential Galantamine Guanine Nucleotides Guanosine Diphosphate Guanosine Monophosphate Guanosine Triphosphate Hexokinase Interphase Brief Psychiatric Rating Scale Type C Phospholipases Phospholipase D Pyruvate Dehydrogenase Complex Lipid Peroxidation Complement C1q Complement C3a Cohort Effect Placebo Effect G0 Phase G1 Phase G2 Phase Antigens, CD45 GTP-Binding Protein Regulators Guanine Nucleotide Exchange Factors Lipid Metabolism Complement C5b DNA Fragmentation Diffusion Tensor Imaging Sirtuin 1 An endophenotype (also known as intermediate phenotype) is a quantitative biological trait that is reliable in reflecting the function of a discrete biological system and is reasonably heritable, and as such is more closely related to the root cause of the disease than the broad clinical phenotype. Endophenotypes An endophenotype (also known as intermediate phenotype) is a quantitative biological trait that is reliable in reflecting the function of a discrete biological system and is reasonably heritable, and as such is more closely related to the root cause of the disease than the broad clinical phenotype. https://www.sciencedirect.com/topics/neuroscience/endophenotype Receptors, Ionotropic Glutamate Cholinergic Neurons Cell Cycle Checkpoints G2 Phase Cell Cycle Checkpoints G1 Phase Cell Cycle Checkpoints Non-invasive methods of visualizing the central nervous system, especially the brain, by various imaging modalities. Neuroimaging Non-invasive methods of visualizing the central nervous system, especially the brain, by various imaging modalities. https://www.ncbi.nlm.nih.gov/mesh/68059906 Methods for visualizing regional blood flow, metabolic, electrical, or other physiological activities in the central nervous system using various imaging modalities. Functional Neuroimaging Methods for visualizing regional blood flow, metabolic, electrical, or other physiological activities in the central nervous system using various imaging modalities. https://www.ncbi.nlm.nih.gov/mesh/68059907 Immunoreceptor Tyrosine-Based Activation Motif Data are obtained from groups who have been exposed, or not exposed, to the new technology or factor of interest (eg from databases). No allocation of exposure is made by the researcher. Best for study the effect of predictive risk factors on an outcome. ENPADASI_WP4 true Cohort Study http://www.cebm.net/study-designs/ A study that examines the relationship between diseases (or other health-related characteristics) and other variables of interest as they exist in a defined population at one particular time (ie exposure and outcomes are both measured at the same time). Best for quantifying the prevalence of a disease or risk factor, and for quantifying the accuracy of a diagnostic test. ENPADASI_WP4 true Cross-Sectional Survey http://www.cebm.net/study-designs/ A material entity that has a measurable quality or process profile(s), which can be used as an indicator of an underlying biological state or identity. The NIH Biomarkers and Surrogate Endpoint Working Group defined a biomarker as “A characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention” (https://pubmed.ncbi.nlm.nih.gov/11240971/). However, the definition of 'characteriistc' is unclear, so we do not use the exact definintion in the ontology. Yingtong Liu, Anthony Huffman, Oliver He https://en.wikipedia.org/wiki/Biomarker https://en.wikipedia.org/wiki/Biomarker_(cell) https://en.wikipedia.org/wiki/Biomarker_(medicine) biomarker Anthony Huffman, Oliver He A biomarker that is indicative of an immune response https://pubmed.ncbi.nlm.nih.gov/22072636/ https://pubmed.ncbi.nlm.nih.gov/32286245/ immune biomarker Anthony Huffman, Oliver He cytokine biomarker Anthony Huffman, Oliver He inflammatory cytokine biomarker A time quality inhering in a bearer by virtue of how long the bearer has existed. quality PATO:0000011 age An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved. quality PATO:0000047 biological sex A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc). PATO:0001647 relational shape quality quality PATO:0000052 Shapes are invariant on size transformations. Shapes can be subdivided into 2D and 3D shapes, We can also make a distinction between shapes of complete self-connected objects, and shapes of parts of objects. shape A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time. quality PATO:0000161 rate A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes. quality PATO:0000383 female A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes. quality PATO:0000384 male A shape quality inhering in a bearer by virtue of the bearer's terminating abruptly by having or as if having an end or point cut off. truncate quality PATO:0000936 truncated A quality which inheres in a continuant. PATO:0001237 PATO:0001238 snap:Quality monadic quality of a continuant multiply inhering quality of a physical entity quality of a continuant quality of a single physical entity quality of an object quality of continuant monadic quality of an object monadic quality of continuant quality PATO:0001241 Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles. physical object quality Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. https://orcid.org/0000-0003-2569-1939 | https://orcid.org/0000-0002-7535-4407 GO:0043195 PMID:23903188 pre-synaptic terminal Planarian_Anatomy presynaptic terminal An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof. natural protein native protein protein PR:000000001 The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB]. protein A protein that contains a Rel homology domain (RHD) (Pfam:PF00554) followed by an IPT/TIG domain (Pfam:PF01833). PANTHER:PTHR12533 protein PR:000003112 Category=family. NFAT protein A protein that is a translation product of the human APP gene or a 1:1 ortholog thereof. ABPP AG APP APPI CVAP PN-II PreA4 alzheimer disease amyloid A4 protein homolog alzheimer disease amyloid protein amyloid beta A4 protein amyloid precursor protein amyloid-beta A4 protein amyloidogenic glycoprotein cerebral vascular amyloid peptide protease nexin-II protein A4 AD1 PR:000004168 Category=gene. Requested by=Alzforum. amyloid-beta precursor protein A protein that is produced as the result of proteolytic processing of a longer protein. ClvPrd peptide polypeptide protein PR:000018264 proteolytic cleavage product A protein that is a neurotrophic polypeptide factor that regulates neuronal differentiation and is essential for neuronal survival, neurite growth and plasticity. It contains a signal peptide, a propeptide, and a C-terminal Nerve growth factor family (Pfam:PF00243) domain. PIRSF:PIRSF001789 protein PR:000021998 Category=family. neurotrophin An amyloid-beta precursor protein proteolytic cleavage product that is the C-terminal product of cleavage by beta-secretase of certain amyloid-beta precursor protein isoforms, signal peptide removed form. Example: UniProtKB:P05067-1, 672-770. APP-C99 protein PR:000025580 Category=modification. Requested by=Alzforum. C99 An amyloid-beta precursor protein proteolytic cleavage product that is the C-terminal product of cleavage by alpha-secretase of certain amyloid-beta precursor protein isoforms, signal peptide removed form. Example: UniProtKB:P05067-1, 688-770. APP-C83 protein PR:000025581 Category=modification. Requested by=Alzforum. C83 A pathway is a set of inter-connected reactions and interactions whose delineation and scope are used as a model for exploring and studying, describing and understanding the working of and relationships between biomolecules within a context. pathway PW:0000001 pathway The secreted glycoproteins of the Wnt family regulate a wide spectrum of developmental processes and they are also playing important roles in the adult organism. Deregulation of Wnt cascades has oncogenic effects and is responsible for tumorigenesis in adults. pathway KEGG:04310 PW:0000008 Wnt signaling pathway Insulin, the peptide hormone, secreted by the pancreatic beta cells, plays essential roles in glucose and energy homeostasis. Insulin signaling activates two main intracellular pathways to regulate carbohydrate and fat metabolism and to prompt glucose absorption in insulin sensitive tissues such as skeletal muscle and adipocytes. Deregulation of the pathway has been associated with a number of conditions, primarily diabetes. pathway KEGG:04910 PID:200014 SMP:00391 PW:0000143 insulin signaling pathway mTOR signaling pathway regulates cellular processes such as translation, ribosome biogenesis, cell growth and autophagy and is regulated or responds to growth factors, energy metabolites and/or levels of nutrients. pathway KEGG:04150 PID:200096 PW:0000180 mTOR signaling pathway The release pathway of neurotransmitter filled synaptic vesicles. VPetri 2016-01-14T11:49:08Z pathway PW:0002425 synaptic vesicle exocytosis pathway The carriage of a solute across a biological membrane from low to high concentration which requires the expenditure of (metabolic) energy. rex.oboInOwl REX:0000120 active transport Comparison of outcomes, results, responses, etc for different techniques, therapeutic approaches or other inputs. http://purl.bioontology.org/ontology/MESH/D003160 Sufficient SCDO:0000268 MESH:D003160 Comparative Studies Comparative Study Laboratory tests used to evaluate how well the kidneys are working through examination of blood and urine. http://purl.bioontology.org/ontology/MESH/D007677 Sufficient SCDO:0000676 MESH:D007677 Kidney Function Tests Renal Function Test Renal Function Tests Kidney Function Test A regulatory_region composed of the TSS(s) and binding sites for TF_complexes of the core transcription machinery. A region (DNA) to which RNA polymerase binds, to begin transcription. INSDC_feature:regulatory http://en.wikipedia.org/wiki/Promoter INSDC_qualifier:promoter promoter sequence sequence SO:0000167 This term is mapped to MGED. Do not obsolete without consulting MGED ontology. The region on a DNA molecule involved in RNA polymerase binding to initiate transcription. Moved from is_a: SO:0001055 transcriptional_cis_regulatory_region as per request from GREEKC initiative in August 2020. Merged with RNA_polymerase_promoter (SO:0001203) Aug 2020. Moved up one level from is_a CRM (SO:0000727) to is_a transcriptional_cis_regulatory_region (SO:0001055) as part of the GREEKC work January 2021. Pascale Gaudet from Gene Ontology pointed out that CRM can be located upstream of the promoter and therefore cannot include the promoter. promoter Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene (or the product of other non coding RNA genes. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (usually via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors. SO:0000649 INSDC_feature:ncRNA http://en.wikipedia.org/wiki/MiRNA http://en.wikipedia.org/wiki/StRNA INSDC_qualifier:miRNA micro RNA microRNA small temporal RNA stRNA sequence SO:0000276 miRNA a case-control study design is a observation study design which assess the risk of particular outcome (a trait or a disease) associated with an event (either an exposure or endogenous factor). A case-control study design therefore declares an exposure variable which is dichotomous in nature (exposed/non-exposed) and an outcome variable, which is also dichotomous (case or control), thus giving the name to the design. During the execution of the design, a case control study defines a population and counts the events to determine their frequency. Alejandra Gonzalez-Beltran Orlaith Burke Philippe Rocca-Serra STATO, adapted from: http://www.drcath.net/toolkit/casecontrol.html case-control study design Odds ratio is a ratio that measures effect size, that is the strength of association between 2 dichotomous variables, one describing an exposure and one describing an outcome. It represents the odds that an outcome will occur given a particular exposure, compared to the odds of the outcome occurring in the absence of that exposure ( the probability of the event occuring divided by the probability of an event not occurring). The odds ratio is a ratio of describing the strength of association or non-independence between two binary data values by forming the ratio of the odds for the first group and the odds for the second group. Odds ratio are used when one wants to compare the odds of something occurring to two different groups. Alejandra Gonzalez-Beltran Orlaith Burke Philippe Rocca-Serra http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938757/ http://www.stats.org/stories/2008/odds_ratios_april4_2008.html OR odds ratio A ratio is a data item which is formed with two numbers r and s is written r/s, where r is the numerator and s is the denominator. The ratio of r to s is equivalent to the quotient r/s. review formal definition as both numerator and denominator should be of the same type, not just some data item Alejandra Gonzalez-Beltran Orlaith Burke Philippe Rocca-Serra adapted from Wolfram Alpha: https://www.wolframalpha.com/share/clip?f=d41d8cd98f00b204e9800998ecf8427efdcsig76g7 ratio prevalence is a ratio formed by the number of subjects diagnosed with a disease divided by the total population size. Philippe Rocca-Serra adapted from: https://www.health.ny.gov/diseases/chronic/basicstat.htm prevalence Incidence is the ratio of the number of new cases of a disease divided by the number of persons at risk for the disease. Philippe Rocca-Serra adapted from: https://www.health.ny.gov/diseases/chronic/basicstat.htm incidence mortality is a ratio formed by the number of deaths due to a disease divided by the total population size. Philippe Rocca-Serra adapted from: https://www.health.ny.gov/diseases/chronic/basicstat.htm mortality Confusion is a neurological and physiological symptom characterized by a disturbance of consciousness characterized by inability to engage in orderly thought or by lack of power to distinguish, choose, or act decisively. symptoms SYMP:0000016 confusion symptoms SYMP:0000022 depression drowsy somnolence symptoms SYMP:0000024 drowsiness Inflammation is a general symptom where there is a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue. symptoms SYMP:0000061 inflammation A sensation perception where there is an unpleasant sensation that usually indicates the body is threatened or damaged. The sensation may be sharp or dull, short-lived or chronic, intermittent or continual, confined to one area or spread over the entire body. symptoms SYMP:0000099 pain seizure symptoms SYMP:0000124 seizure Necrosis is a general symptom where death of a portion of tissue differentially affected by local injury (as loss of blood supply, corrosion, burning, or the local lesion of a disease). symptoms SYMP:0000132 necrosis symptoms SYMP:0000178 weight loss symptoms SYMP:0000271 complex partial seizure symptoms SYMP:0000387 head symptom symptoms SYMP:0000410 neurological and physiological symptom Anxiety is a neurological and physiological symptom characterized by a painful or apprehensive uneasiness of mind usually over an impending or anticipated ill. symptoms SYMP:0000412 anxiety Urticaria is a skin and integumentary tissue symptom characterized by raised red skin wheals (welts) commonly caused by an allergic reaction with wheals that may vary in size from about 5 mm (0.2 inches) in diameter to the size of a dinner plate that are described as severely itchy a stingnig or burning sensation, and having a pale border. hives nettle rash uredo symptoms SYMP:0000434 doid/symp duplicate urticaria Heartburn is a pain characterized by a painful burning feeling in your chest or throat that happens when stomach acid backs up into your esophagus. acid indigestion symptoms SYMP:0000439 heartburn ICD9CM_2005:789.0 ICD9CM_2005:789.00 UMLS_CUI:C0000737 UMLS_ICD9CM_2005_AUI:A0387333 UMLS_ICD9CM_2005_AUI:A0637138 symptoms SYMP:0000457 abdominal pain Nausea is a digestive system symptom characterized by an uneasy or unsettled feeling in the stomach together with an urge to vomit. ICD9CM_2005:787.02 UMLS_CUI:C0375548 UMLS_ICD9CM_2005_AUI:A0750850 symptoms SYMP:0000458 nausea ICD9CM_2005:787 SyOID:5330 UMLS_CUI:C0159058 UMLS_ICD9CM_2005_AUI:A0284224 symptoms SYMP:0000459 digestive system symptom ICD9CM_2005:789 ICD9CM_2005:789.9 SyOID:12097 UMLS_CUI:C0159065 UMLS_ICD9CM_2005_AUI:A0284267 UMLS_ICD9CM_2005_AUI:A0284268 symptoms SYMP:0000461 abdominal symptom A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease. SyOID:14974 symptoms SYMP:0000462 symptom ICD9CM_2005:783 SyOID:2644 UMLS_CUI:C0159041 UMLS_ICD9CM_2005_AUI:A0284163 symptoms SYMP:0000473 nutrition, metabolism, and development symptom ICD9CM_2005:781 SyOID:90 UMLS_CUI:C0159033 UMLS_ICD9CM_2005_AUI:A0284131 symptoms SYMP:0000480 nervous system symptom ICD9CM_2005:788 UMLS_CUI:C0476293 UMLS_ICD9CM_2005_AUI:A0284245 symptoms SYMP:0000486 urinary system symptom ICD9CM_2005:782 ICD9CM_2005:782.9 UMLS_CUI:C0159037 UMLS_ICD9CM_2005_AUI:A0284146 UMLS_ICD9CM_2005_AUI:A0284161 symptoms SYMP:0000488 skin and integumentary tissue symptom Headache is a pain characterized by a pain in the head. ICD9CM_2005:784.0 UMLS_CUI:C0018681 UMLS_ICD9CM_2005_AUI:A0065994 cephalalgia symptoms SYMP:0000504 headache ICD9CM_2005:780 SyOID:777 UMLS_CUI:C0159028 UMLS_ICD9CM_2005_AUI:A0284119 symptoms SYMP:0000567 general symptom Insomnia is a sleep disturbance characterized by prolonged and usually abnormal inability to obtain adequate sleep. ICD9CM_2005:780.52 UMLS_CUI:C0029645 UMLS_ICD9CM_2005_AUI:A0243733 agrypnia symptoms SYMP:0000571 insomnia ICD9CM_2005:786.5 ICD9CM_2005:786.50 UMLS_CUI:C0008031 UMLS_ICD9CM_2005_AUI:A0243830 UMLS_ICD9CM_2005_AUI:A0400627 symptoms SYMP:0000576 chest pain Dizziness is a neurological and physiological symptom characterized by a sensation of unsteadiness accompanied by a feeling of movement within the head. ICD9CM_2005:780.4 UMLS_CUI:C0476206 UMLS_ICD9CM_2005_AUI:A0243727 dizzy symptoms SYMP:0000610 dizziness symptoms SYMP:0000731 renal failure Stroke is a nervous system symptom characterized by a sudden diminution or loss of consciousness, sensation, and voluntary motion caused by rupture or obstruction (as by a clot) of a blood vessel of the brain. apoplexy brain attack cerebral accident cerebrovascular accident symptoms SYMP:0000734 stroke Constipation is a feces and droppings symptom involving the abnormally delayed or infrequent passage of dry hardened feces. symptoms SYMP:0019180 doid/symp duplicate constipation A nervous system symptom that involves, is related to, or emphasizes behavior. behavioral symptom Function-related process is a process that related to the execution of a function, a metafunction, and the malfunction. FBRL: A Function and Behavior Representation Language. Sasajima, M., Kitamura, Y., Ikeda, M. & Mizoguchi, R., In Proc. of IJCAI-95 (pp. 1830-1836), 1995 doi:10.1115/DETC2006-9913 https://doi.org/10.1016/S1474-0346(02)00006-X This tree is based on a functional concept ontology (Kitamura 2002). function-related process Primitive process is a unit of process. Process series at a certain granular level can appear as one primitive process at the higher level. Whether the process is a primitive process or not depends on the setting of the granularity. When one does not consider the details more than a certain level, or a level as the minimum grain size, the process at that level becomes the primitive process. primitive process A role played by the entity which enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size). related molecular function GO:0005216 ion channel Functioning process is a subtype of function-related process: A process that executes and manifests function. functioning process Malfunctioning process is a subtype of function-related process: A process that cannot perform a function appropriately or cannot realize it at all. malfunctioning process Dysfunctioning is a subtype of malfunctioning process: A process that performs an abnormal and incomplete functioning. dysfunctioning Starvation is a subtype of depleting: A process that lessens markedly in quantity of the nourishment. http://purl.bioontology.org/ontology/MESH/D013217 starvation Catalysis role of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. rerlated molecular fuction GO:0004672 protein kinase Mitochondrial dysfunction is a subtype of dysfunctioning: A process that performs an abnormal and incomplete mitochondrial function. mitochondrial dysfunction Protein aggregation is a subtype of molecular assembly: The aggregation, arrangement and bonding together of molecules. http://jglobal.jst.go.jp/en/detail?JGLOBAL_ID=200906073816740790 http://purl.jp/bio/4/id/200906073816740790 protein aggregation Catalysis role of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine. ceramidase A role which enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells. related molecular function GO:0005215 transporter A role played by the entity to initiate or regulate transcription. IMR:0000368 (obsolete) This term is sometimes used for both gene regulatory proteins as well as the general transcription factors. transcription factor A role played by the entity which enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. related molecular function GO:0005267 potassium channel Catalysis role of the reaction: GTP + H2O = GDP + phosphate. EC:3.6.5.- IMR:0000960 (obsolete) related moleular function: GO:0003924 GTPase Catalysis role of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes. IMR:0001166 (obsolete) related molecule fuction GO:0004407 HDAC histone deacetylase Catalysis role of the hydrolysis of a glycerophospholipid. EC:3.1.1 IMR:0000281 (obsolete) related molecular fuction : GO:0004620 phospholipase Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. EC:3.1.3. EC:3.1.3.41 IMR:0000517 (obsolete) phosphoric monoester hydrolase activity NPPase activity related molecular function GO:0016791 phosphatase A role played by the entity which enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. related molecular function GO:0015276 ligand-gated ion channel A role played by the entity of funtion as realizable entity. functional role The process in which one or more ubiquitin groups are added to a protein. protein ubiquitinylation protein ubiquitylation protein ubiquitination ceramide accumulation is a subtype of accumulation of substances in a biological object: A process that keeps ceramide in an organism, tissue, organelle, or cell. ceramide acumulation G protein-coupled receptors GPCR niacin A biological tissue mass, most commonly a mass of nerve cell bodies. TODO - check vert vs invert. Other species: Any of a number of aggregations of neurons, glial cells and their processes, surrounded by a glial cell and connective tissue sheath (plural: ganglia). // Subdivision of neural tree (organ) which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord); together with a nucleus and its associated nerve, it constitutes a neural tree (organ). Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion. // a cluster of nerve cells and associated glial cells (nuclear location) // Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system. A ganglion is a cluster of neurons. It is part of a nervous system. It may include glial cells. The neurons are arranged in a specific constellation: neuronal somata are concentrated at the surface, thus forming a cell cortex, and neurites are concentrated in the centre of the ganglion to form the neuropil. A ganglion is a distinct unit but several ganglia may be anterio-posteriorly joined by connectives or transversally by commissures Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system.[AAO] Structures containing a collection of nerve cell bodies. (Source: BioGlossary, www.Biology-Text.com)[TAO] Subdivision of nervous system which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord. Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion (adapted from Foundational Model of Anatomy)[NLXANAT:100302]. Cranial sensory placodes are focused areas of the head ectoderm of vertebrates that contribute to the development of the cranial sense organs and their associated ganglia. Placodes have long been considered a key character of vertebrates, and their evolution is proposed to have been essential for the evolution of an active predatory lifestyle by early vertebrates.[well established][VHOG] ganglionic AAO:0010426 AEO:0000135 BAMS:G BTO:0000497 CALOHA:TS-0397 EFO:0000899 EHDAA2:0003135 EHDAA:2897 EHDAA:4662 EHDAA:5621 EHDAA:918 EMAPA:32846 EV:0100372 FBbt:00005137 FMA:5884 MA:0002406 MAT:0000207 MAT:0000343 MESH:D005724 MIAA:0000207 MIAA:0000343 NCIT:C12719 NLXANAT:100302 TAO:0000190 TGMA:0001016 UMLS:C0017067 VHOG:0000156 WBbt:0005189 XAO:0000209 ZFA:0000190 uberon ganglia neural ganglion UBERON:0000045 ganglion Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. AAO:0010825 AEO:0000003 BILA:0000003 CARO:0000003 EHDAA2:0003003 EMAPA:0 FBbt:00007001 FMA:305751 FMA:67135 GAID:781 HAO:0000003 MA:0003000 MESH:D000825 TAO:0000037 TGMA:0001823 VHOG:0001759 XAO:0003000 ZFA:0000037 biological structure connected biological structure uberon UBERON:0000061 anatomical structure Anatomical structure that performs a specific function or group of functions [WP]. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. CARO v1 does not include a generic 'organ' class, only simple and compound organ. CARO v2 may include organ, see https://github.com/obophenotype/caro/issues/4 BIRNLEX:4 CARO:0020004 EFO:0000634 EMAPA:35949 ENVO:01000162 FMA:67498 MA:0003001 NCIT:C13018 OpenCyc:Mx4rv5XMb5wpEbGdrcN5Y29ycA OpenCyc:Mx4rwP3iWpwpEbGdrcN5Y29ycA UMLS:C0178784 WBbt:0003760 uberon anatomical unit body organ element UBERON:0000062 organ A multicellular structure that is a part of an organ. currently defined in a very broad sense, may be replaced by more specific classes in the future AAO:0011124 BIRNLEX:16 EFO:0000635 FMA:82472 cardinal organ part uberon regional part of organ UBERON:0000064 organ part Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS. Melissa Haendel 2009-06-18T09:00:04Z BIRNLEX:1157 NCIT:C13040 UMLS:C1518256 part of nervous system uberon UBERON:0000073 regional part of nervous system Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions. NCIT:C13194 UMLS:C0005854 blood-brain barrier uberon BBB UBERON:0000120 blood brain barrier A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses. UBERON:0005163 CARO:0001001 FBbt:00005099 NLX:147821 funiculus nerve fiber bundle neural fiber bundle uberon UBERON:0000122 neuron projection bundle A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO) A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO). Anatomical structure consisting of a discrete aggregate of neuronal soma[GO][GO_REF:0000021]. Proposed CUMBO def from MM: A subcortical part of the nervous system consisting of a relatively compact group of cells that is distinguishable histologically that share a commonality of cytoarchitecture, chemoarchitecturel and connectivity. (comments: I put in 'subcortical' because I don't think we consider either the cerebellar cortex or cerebral cortex to be nuclei. Some people distinguish between a nucleus and a laminar structure (see Wikipedia definition). However, there are structures identified as nuclei that are laminar, e.g., lateral geniculate nucleus, although they are not laminated in all species. Also, I put in 'relatively compact' and 'distiguishable by histology' because we have groups of cells, e.g., cholinergic cell groups, doparminergic cell groups that are related on the 3 criteria but which we don't tend to consider nuclei because they don't occupy an easily defined territory. But all is open to debate. nucleus AEO:0000136 FMA:83686 NCIT:C13197 NLX:28443 nervous system nucleus neuraxis nucleus neuronal nucleus nucleus of CNS uberon nucleus of neuraxis UBERON:0000125 neural nucleus A fluid that is composed of blood plasma and erythrocytes. This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. A complex mixture of cells suspended in a liquid matrix that delivers nutrients to cells and removes wastes. (Source: BioGlossary, www.Biology-Text.com)[TAO] Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO] relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO] Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrates phyla. (...) There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast.[well established][VHOG] AAO:0000046 BTO:0000089 CALOHA:TS-0079 EFO:0000296 EHDAA2:0000176 EHDAA:418 EMAPA:16332 ENVO:02000027 EV:0100047 FMA:9670 GAID:965 MA:0000059 MESH:D001769 MIAA:0000315 NCIT:C12434 OpenCyc:Mx4rvVjI8JwpEbGdrcN5Y29ycA TAO:0000007 UMLS:C0005767 VHOG:0000224 XAO:0000124 ZFA:0000007 galen:Blood portion of blood vertebrate blood uberon whole blood UBERON:0000178 blood A ridge on the cerebral cortex. It is generally surrounded by one or more sulci . BTO:0002495 FMA:83874 NCIT:C32290 UMLS:C0458308 cerebral gyrus gyrus of neuraxis neuraxis gyrus uberon folia folium folium of brain gyri gyri of cerebrum gyrus of cerebral hemisphere gyrus of cerebrum UBERON:0000200 gyrus https://github.com/obophenotype/uberon/issues/573 functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. parenchymal Early in development the mammalian embryo has three distinct layers: ectoderm (external layer), endoderm (internal layer) and in between those two layers the middle layer or mesoderm. The parenchyma of most organs is of ectodermal (brain, skin) or endodermal origin (lungs, gastrointestinal tract, liver, pancreas). The parenchyma of a few organs (spleen, kidneys, heart) is of mesodermal origin. The stroma of all organs is of mesodermal origin the FMA definition is more restrictive, and limits this to solid organs. This would seem to cause problems for the lung parenchyma, except FMA classifies Lung as solid rather than cavitated EHDAA:3015 EHDAA:3905 EHDAA:3999 EHDAA:4005 EHDAA:6899 EHDAA:6903 EHDAA:6994 EHDAA:8086 EHDAA:9182 EHDAA:9190 EHDAA:9196 EHDAA:9202 FMA:45732 NCIT:C74601 UMLS:C0933845 uberon UBERON:0000353 parenchyma The anterior part of the frontal lobes of the brain, lying in front of the motor and premotor areas.nnThis brain region has been implicated in planning complex cognitive behaviors, personality expression, decision making and moderating correct social behavior. The basic activity of this brain region is considered to be orchestration of thoughts and actions in accordance with internal goals.nnThe most typical psychological term for functions carried out by the pre-frontal cortex area is executive function. Executive function relates to abilities to differentiate among conflicting thoughts, determine good and bad, better and best, same and different, future consequences of current activities, working toward a defined goal, prediction of outcomes, expectation based on actions, and social 'control' (the ability to suppress urges that, if not suppressed, could lead to socially-unacceptable outcomes).nnMany authors have indicated an integral link between a person's personality and the functions of the prefrontal cortex. - definition adapted from Wikipedia. TODO - check MA BAMS:FrA BTO:0002807 DHBA:10172 EFO:0001384 EMAPA:35356 FMA:224850 GAID:676 MA:0000906 MESH:A08.186.211.730.885.213.270.700 NLXANAT:090801 prefrontal association cortex uberon frontal association cortex prefrontal association complex UBERON:0000451 prefrontal cortex http://upload.wikimedia.org/wikipedia/commons/5/59/Gray726-Brodman-prefrontal.svg Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. AAO:0010839 AEO:0000004 BILA:0000004 CALOHA:TS-2101 CARO:0000004 EHDAA2:0003004 EMAPA:35178 FBbt:00007019 FMA:9669 HAO:0000004 MA:0002450 NCIT:C13236 SPD:0000008 TAO:0001487 TGMA:0001824 VHOG:0001726 XAO:0004001 ZFA:0001487 galen:BodySubstance body fluid or substance body substance organism substance portion of body substance portion of organism substance uberon UBERON:0000463 organism substance Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. lumen space AAO:0010110 AEO:0000005 BILA:0000005 CARO:0000005 EHDAA2:0003005 FBbt:00007017 FMA:5897 HAO:0000005 NCIT:C94478 TAO:0001668 TGMA:0001825 UMLS:C0524461 VHOG:0001728 XAO:0003190 ZFA:0001643 lumen space uberon anatomical spaces UBERON:0000464 anatomical space Anatomical entity that has mass. AAO:0010264 AEO:0000006 BILA:0000006 CARO:0000006 EHDAA2:0003006 FBbt:00007016 FMA:67165 HAO:0000006 TAO:0001836 TGMA:0001826 VHOG:0001721 uberon UBERON:0000465 material anatomical entity Anatomical entity that has no mass. AAO:0010265 AEO:0000007 BILA:0000007 CARO:0000007 EHDAA2:0003007 FBbt:00007015 FMA:67112 HAO:0000007 TAO:0001835 TGMA:0001827 VHOG:0001727 immaterial physical anatomical entity uberon UBERON:0000466 immaterial anatomical entity Anatomical group that has its parts adjacent to one another. Will be obsoleted in CARO v2 [https://github.com/obophenotype/caro/issues/3] AAO:0010009 AEO:0000041 BILA:0000041 CARO:0000041 EHDAA2:0003041 FBbt:00007277 FMA:49443 HAO:0000041 TADS:0000605 TAO:0001478 TGMA:0001842 VHOG:0001737 XAO:0003160 ZFA:0001478 uberon UBERON:0000477 anatomical cluster Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. changed label and definition to reflect CARO2 AAO:0000607 AAO:0010054 AEO:0000043 BILA:0000043 BIRNLEX:19 CALOHA:TS-2090 CARO:0000043 EHDAA2:0003043 EMAPA:35868 FBbt:00007003 FMA:9637 HAO:0000043 MA:0003002 MESH:D014024 NCIT:C12801 TAO:0001477 TGMA:0001844 UMLS:C0040300 VHOG:0001757 WBbt:0005729 XAO:0003040 ZFA:0001477 galen:Tissue portion of tissue tissue portion simple tissue uberon UBERON:0000479 tissue Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. AAO:0010048 AEO:0000055 BILA:0000055 CARO:0000055 EHDAA2:0003055 FBbt:00007010 HAO:0000055 TAO:0001488 TGMA:0001847 VHOG:0001762 XAO:0003037 ZFA:0001488 uberon multi-tissue structures UBERON:0000481 multi-tissue structure Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. The two basic types of metazoan tissue are epithelial and connective. The simplest metazoans, and developmental stages of many primitive invertebrates, consist solely of these two layers. Thus, epithelial and connective tissues may be the primary (original) tissues of metazoans, and both are important in the functional organization of animals.[well established][VHOG] epithelial AAO:0000144 AAO:0010055 AEO:0000066 BILA:0000066 BTO:0000416 CALOHA:TS-0288 CARO:0000066 EHDAA2:0003066 EMAPA:32738 FBbt:00007005 FMA:9639 GAID:402 HAO:0000066 MA:0003060 MESH:D004848 NCIT:C12710 TAO:0001486 UMLS:C0014609 VHOG:0000387 XAO:0003045 ZFA:0001486 epithelial tissue portion of epithelium uberon UBERON:0000483 Editor note: surface epithelium may contain non-epithelial cells, such as melanocytes, lymphocytes and dendritic cells, within the sheet of epithelial cells. Do we consider these part of the epithelium, or located-in it? epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]. Unilaminar epithelium that consists of a single layer of squamous cells.[CARO] AAO:0010066 AEO:0000070 BILA:0000070 BTO:0002073 CARO:0000070 EHDAA2:0003070 FMA:45565 HAO:0000070 NCIT:C13178 TAO:0001498 UMLS:C0836133 XAO:0004010 ZFA:0001498 epithelium simplex squamosum uberon simple squamous epithelia UBERON:0000487 simple squamous epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg Compound organ that contains one or more macroscopic anatomical spaces. this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future AAO:0010016 AEO:0000072 BILA:0000072 CARO:0000072 EHDAA2:0003072 FMA:55671 HAO:0000072 TAO:0001490 TGMA:0001857 VHOG:0001730 XAO:0003165 ZFA:0001490 cavitated organ uberon cavitated compound organs UBERON:0000489 cavitated compound organ Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]. consider adding disjointness axiom between unilaminar and multilaminar - but note that this will render EHDAA2:0003244 (chorionic trophoblast) unsatisfiable Epithelium that consists of a single layer of epithelial cells.[CARO] AAO:0010062 AEO:0000073 BILA:0000073 BTO:0002073 CARO:0000073 EHDAA2:0003073 FMA:45561 HAO:0000073 NCIT:C33554 TAO:0001495 UMLS:C0682574 XAO:0004007 ZFA:0001495 simple epithelium uberon unilaminar epithelia UBERON:0000490 unilaminar epithelium The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. requires review for applicability to invertebrate structures, e.g. synganglion Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system.[TAO] Part of the central nervous system situated within the cranium and composed of both nerve cell bodies and nerve fibers.[AAO] The part of the central nervous system contained within the cranium, comprising the forebrain, midbrain, hindbrain, and metencephalon. It is derived from the anterior part of the embryonic neural tube (or the encephalon). Does not include retina. (CUMBO) (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG] AAO:0010478 ABA:Brain BAMS:Br BAMS:Brain BILA:0000135 BIRNLEX:796 BTO:0000142 CALOHA:TS-0095 DHBA:10155 EFO:0000302 EHDAA2:0000183 EHDAA:2641 EHDAA:6485 EMAPA:16894 EV:0100164 FBbt:00005095 FMA:50801 GAID:571 HBA:4005 MA:0000168 MAT:0000098 MBA:8 MBA:997 MESH:D001921 MIAA:0000098 NCIT:C12439 OpenCyc:Mx4rvVjT65wpEbGdrcN5Y29ycA PBA:3999 TAO:0000008 UMLS:C0006104 UMLS:C1269537 VHOG:0000157 XAO:0000010 ZFA:0000008 galen:Brain http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=21 uberon encephalon suprasegmental levels of nervous system suprasegmental structures synganglion the brain UBERON:0000955 brain The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex. We follow NIFSTD in defining cerebral cortex and including both neocortex and hippocampal formation (DG+hippocampus). The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2-4 mm (0.08-0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts. [WP,unvetted][Wikipedia:Cerebral_cortex]. Migration of neurons from the basal or striatal portions of the anterior part of the neural tube occurs to varying degrees in different vertebrate classes, but a true cerebral cortex is generally acknowledged to have made its first appearance in reptiles. The definition can be unambiguous, since 'cortex' simply implies the existence of a surface neuronal layer with an overlying 'zonal lamina' or 'molecular' layer containing dendrites and axons, which is separated from the underlying basal 'matrix' by white matter. Although reptilian cerebral cortex does indeed fulfill these conditions in certain locations, the separation from striatal structures is often indistinct, so that it may even be argued that some primitive dipnoans possess a pallium or cortex. Nevertheless, an extensive laminated layer separated by underlying white matter is well represented only in reptiles and mammals.[well established][VHOG] hagfishes have independently evolved a highly laminated cerebral cortex, comparable in many ways to the cerebral cortex of mammals [http://icb.oxfordjournals.org/content/42/4/743] BAMS:C BAMS:CTX BAMS:Cerebral_cortex BAMS:Cx BIRNLEX:1494 BM:Tel-Cx BTO:0000233 CALOHA:TS-0091 DHBA:10159 EFO:0000328 EHDAA2:0000234 EHDAA:5464 EMAPA:17544 EV:0100166 FMA:61830 GAID:629 HBA:4008 MA:0000185 MAT:0000108 MBA:688 MESH:A08.186.211.730.885.213 MIAA:0000108 NCIT:C12443 PBA:128011354 UMLS:C0007776 VHOG:0000722 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=39 cortex of cerebral hemisphere uberon brain cortex cortex cerebralis cortex cerebri cortical plate (CTXpl) cortical plate (areas) pallium of the brain UBERON:0000956 cerebral cortex The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. Part of the nervous system which includes the brain and spinal cord.[AAO] The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG] AAO:0000090 BAMS:CNS BILA:0000080 BIRNLEX:1099 BTO:0000227 CALOHA:TS-0150 EFO:0000908 EHDAA2:0000225 EHDAA:828 EMAPA:16470 EMAPA:16754 EV:0100163 FBbt:00005094 FMA:55675 GAID:570 MA:0000167 MAT:0000457 MESH:D002490 NCIT:C12438 OpenCyc:Mx4rvzYt3pwpEbGdrcN5Y29ycA TAO:0000012 UMLS:C0927232 VHOG:0000293 XAO:0000215 ZFA:0000012 CNS systema nervosum centrale cerebrospinal axis uberon neuraxis UBERON:0001017 central nervous system A group of axons linking two or more neuropils and having a common origin, termination[FBbt]. White matter structure of CNS that contains axons that arise predominantly in one central nervous system part and terminate in another. Tracts are generally named by their region or origin followed by their region of primary termination, e.g., mammillothalamic tract contains axons that arise from neurons in the mammillary bodies and terminate in the thalamus. (CUMBO) BIRNLEX:1649 EV:0100304 FBbt:00005100 FMA:83847 NLX:147822 axonal tract neuraxis tract tract of neuraxis nerve tract uberon nerve tract tract UBERON:0001018 WP says this is the analog of peripheral nerves in CNS. axon tract Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. AAO:0010841 AEO:0000000 BILA:0000000 BIRNLEX:6 CARO:0000000 EHDAA2:0002229 FBbt:10000000 FBbt_root:00000000 FMA:62955 HAO:0000000 MA:0000001 NCIT:C12219 TAO:0100000 TGMA:0001822 UMLS:C1515976 WBbt:0000100 XAO:0000000 ZFA:0100000 uberon UBERON:0001062 anatomical entity http://purl.obolibrary.org/obo/FMA_62955 Epithelial layer that lines the intestine. Simple columnar epithelium that lines the intestine, sometimes pseudostratified, with absorptive brush-border cells and mucous goblet cells clearly visible. Crosnier et al. 2005[TAO] BTO:0000781 EMAPA:32873 FMA:17229 MA:0001536 NCIT:C49240 TAO:0005124 UMLS:C0226890 ZFA:0005124 bowel epithelial tissue bowel epithelium epithelial tissue of bowel epithelial tissue of intestine epithelium of bowel epithelium of intestine intestine epithelial tissue villous epithelium uberon intestine epithelium UBERON:0001277 intestinal epithelium A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord. many sources state the CP as sole producer of CSF, but this is disputed [DOI:10.1007/s11064-015-1581-6] Portion of organism substance that is a clear fluid that occupies the subarachnoid space and the ventricular system around and inside the brain.[TAO] In vertebrates, at early stages of Central Nervous System (CNS) development, the architecture of the brain primordium reveals the presence of the cavity of brain vesicles, which is filled by Embryonic Cerebro-Spinal Fluid (E-CSF). (...) Rat and chick E-CSF proteomes are similar, although rat is more complex in certain groups of proteins, e.g., apolipoproteins, which may be involved in the control of neural diversity, and has soluble enzymes present, just like adult human CSF, but unlike chick E-CSF, revealing phylogenetic brain differences between these groups of vertebrates.[uncertain][VHOG] EHDAA2 models this as developing from CP, which is wrong the FMA def states that this is subarachnoid spaces only. ZFA def states subarachnoid spaces and brain ventricles, but not SC (and has part_of to brain). Circulation: It circulates from the lateral ventricles to the foramen of Monro (Interventricular foramen), third ventricle, aqueduct of Sylvius (Cerebral aqueduct), fourth ventricle, foramen of Magendie (Median aperture) and foramina of Luschka (Lateral apertures), subarachnoid space over brain and spinal cord. It should be noted that the CSF moves in a pulsatile manner throughout the CSF system with nearly zero net flow. CSF is reabsorbed into venous sinus blood via arachnoid granulations. BIRNLEX:1798 BTO:0000237 CALOHA:TS-0130 EFO:0000329 EHDAA2:0004441 ENVO:02000029 EV:0100311 FMA:20935 GAID:1181 MA:0002503 MAT:0000499 MESH:A12.207.268 NCIT:C12692 TAO:0002184 UMLS:C0007806 VHOG:0001278 ZFA:0001626 CSF cerebral spinal fluid uberon liquor cerebrospinalis spinal fluid UBERON:0001359 cerebrospinal fluid Outermost layer of an organ[WP]. cortical this class is used more generically than in FMA, and includes e.g. cortex of hair EFO:0000383 EHDAA:9344 FMA:61109 galen:Cortex cortex cortex of organ uberon UBERON:0001851 cortex One of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter.[FMA]. Part of the telencephalon consisting of either of the two smooth, elongated halves of the cerebrum.[AAO] The presence of paired evaginated hemispheres and olfactory bulbs in both agnathan and gnathostome radiations suggests that such hemispheres were also present in the common ancestor.[well established][VHOG] AAO:0010480 BAMS:HEM BIRNLEX:1042 BTO:0000231 CALOHA:TS-2007 DMBA:15739 EFO:0002521 EMAPA:16653 FMA:61817 MA:0000133 MBA:403 NCIT:C12351 OpenCyc:Mx4rvigx5ZwpEbGdrcN5Y29ycA UMLS:C0228174 UMLS:C0242202 VHOG:0001639 galen:CerebralHemisphere http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=241 uberon cerebrum hemisphere hemispheric regions hemispherium cerebri medial amygdalar nucleus nucleus amygdaloideus medialis nucleus medialis amygdalae UBERON:0001869 cerebral hemisphere http://upload.wikimedia.org/wikipedia/commons/9/92/Hemispheres.png Lower lateral part of the cerebral hemisphere. (MSH). BAMS:TL BAMS:Temporal_lobe BIRNLEX:1160 BTO:0001355 CALOHA:TS-1020 DHBA:12139 EFO:0000917 EMAPA:18797 EV:0100169 FMA:61825 GAID:635 HBA:4132 MAT:0000508 MESH:A08.186.211.730.885.213.863 NCIT:C12353 OpenCyc:Mx4rwQLi-ZwpEbGdrcN5Y29ycA UMLS:C0039485 UMLS:C1268978 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=125 lobus temporalis temporal cortex uberon UBERON:0001871 Boundary notes: It is bounded dorsally by the lateral fissure and posteriorly by an arbitrary border shared with the occipital lobe. [Wikipedia:Temporal_lobe] temporal lobe http://upload.wikimedia.org/wikipedia/commons/9/91/Gray730.png Upper central part of the cerebral hemisphere. (MSH). parietal region BAMS:Parietal_lobe BIRNLEX:1148 BTO:0001001 CALOHA:TS-0747 DHBA:12131 EFO:0000914 EV:0100168 FMA:61826 GAID:680 HBA:4084 MAT:0000506 MESH:A08.186.211.730.885.213.670 NCIT:C12354 OpenCyc:Mx4rvg-typwpEbGdrcN5Y29ycA UMLS:C0030560 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=95 regio parietalis uberon lobus parietalis UBERON:0001872 parietal lobe http://upload.wikimedia.org/wikipedia/commons/b/b2/Gray726_parietal_lobe.png Subcortical brain region lying anterior to the hippocampal formation in the temporal lobe and anterior to the temporal horn of the lateral ventricle in some species. It is usually subdivided into several groups. Functionally, it is not considered a unitary structure (MM). Subdivision of basal ganglion of telencephalon which is an almond-shaped gray mass in the dorsomedial part of the temporal lobe[FMA:61841] One part of the striatum is called the archistriatum. (...) The archistriatum of fishes consists of several indistinctly segregated nuclei called the amygdaloid (...) complex. Tetrapods retain the structure, and in mammals the corresponding amygdala is a globular mass that tends to be ventral to the other basal nuclei.[well established][VHOG] amygdalar MA and FMA differ on relationship to basal ganglion. The FMA text def suggests a subdivision, but it is classified as a subtype BAMS:AMY BAMS:Amg BAMS:Amy BAMS:Amygdala BAMS:Amygdaloid_complex BIRNLEX:1241 BM:Tel-Am BTO:0001042 CALOHA:TS-0037 DHBA:10361 EFO:0000252 EMAPA:32672 EMAPA:36051 EV:0100189 EV:0100190 FMA:61841 GAID:616 HBA:4327 MA:0000887 MAT:0000289 MESH:A08.186.211.577.090 MIAA:0000289 NCIT:C12440 OpenCyc:Mx4rwJC_2ZwpEbGdrcN5Y29ycA PBA:4002 UMLS:C0002708 VHOG:0001277 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=237 amygdaloid body amygdaloid complex amygdaloid nuclear complex amygdaloid nuclear groups archistriatum uberon amygdaloid area amygdaloid nuclear group amygdaloid nucleus corpus amygdalae corpus amygdaloideum nucleus amygdalae UBERON:0001876 amygdala http://upload.wikimedia.org/wikipedia/commons/8/8b/Amyg.png The division of the forebrain that develops from the foremost primary cerebral vesicle. The more posterior and ventral of two forebrain neuromeres, the other being the telencephalon; major derivatives are the eye cups, the brain pretectal region, the thalamus, hypothalamus, and epithalamus (including the habenula and epiphysis). Kimmel et al, 1995.[TAO] Unpaired part of the forebrain comprised of three major parts; the epithalamus, thalamus, and hypothalamus.[AAO] Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG] diencephalic in ABA, this is part of the brain stem DiE AAO:0010481 BAMS:DI BAMS:Di BAMS:DiE BAMS:IB BAMS:Zh. BIRNLEX:1503 BM:Die BTO:0000342 CALOHA:TS-0199 DHBA:10389 DMBA:16308 EFO:0000911 EHDAA2:0000385 EHDAA:1969 EHDAA:2645 EHDAA:3472 EMAPA:16896 EV:0100194 FMA:62001 GAID:618 HBA:4391 MA:0000171 MAT:0000420 MBA:1129 MESH:A08.186.211.730.385 MIAA:0000420 NCIT:C12456 OpenCyc:Mx4rwC-V0JwpEbGdrcN5Y29ycA PBA:128013010 TAO:0000101 UMLS:C0012144 VHOG:0000318 XAO:0000013 ZFA:0000101 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=288 between brain interbrain mature diencephalon thalamencephalon uberon betweenbrain diencephalon UBERON:0001894 diencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg the group of neurons that serve as the primary processor of visual information received from the retina via the optic tract and send processed information to the visual cortex of the occipital lobe BTO has distinct classes for body and nucleus, but other sources treat as identical LGN BAMS:C.gl. BAMS:LG BIRNLEX:1662 BTO:0004366 BTO:0004367 DHBA:10429 EFO:0001988 EMAPA:35478 EV:0100219 FMA:62209 MA:0000869 NCIT:C32556 PBA:128013070 UMLS:C0086526 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=352 corpus geniculatum laterales lateral geniculate complex lateral geniculate nucleus nucleus geniculatus lateralis uberon LGB corpus geniculatum externum corpus geniculatum laterale corpus geniculatus lateralis external geniculate body nucleus corporis geniculati lateralis UBERON:0001926 lateral geniculate body http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray719.png An area of cerebral cortex defined on the basis of cytoarchitecture that have six layers. Starting from the cortical surface the layers are: molecular layer (I), external granular layer (II), external pyramidal layer (III), internal granular layer (IV), internal pyramidal layer (V), and multiform layer (VI). Neocortex is most prominent in the frontal lobe, the parietal lobe, the temporal lobe and the occipital lobe, less so in the cingulate gyrus, the parahippocampal gyrus and the insula. It is composed of two subdivisions: true isocortex and proisocortex (Carpenter-83)(NN). The 6-layer neocortex is well conserved in all extant mammals, but not present in birds or reptils BAMS:ISO BAMS:Iso-cortex BAMS:NCX BIRNLEX:2547 BTO:0000920 DHBA:10160 EHDAA2:0004662 EMAPA:32842 EMAPA:35589 FMA:62429 GAID:677 MA:0002754 MBA:315 MESH:A08.186.211.730.885.213.420 PBA:294021746 UMLS:C0175173 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=757 cerebral neocortex homogenetic cortex homotypical cortex isocortex (sensu lato) neocortex (isocortex) neopallial cortex neopallium isocortex uberon iso-cortex nonolfactory cortex nucleus hypoglossalis UBERON:0001950 neocortex http://upload.wikimedia.org/wikipedia/commons/7/77/Neocortex.jpg A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]. endothelial BTO:0000393 CALOHA:TS-0278 EFO:0002548 FMA:63916 GAID:520 MESH:D004727 NCIT:C12481 UMLS:C0014257 galen:Endothelium uberon UBERON:0001986 The term 'endothelium' has been either restricted to the continuous cell layer of the vertebrates, as we are assuming here, or applied to all the cells able to adhere to the luminal surface of the vascular basement membrane (Casley-Smith 1980) endothelium A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons. Multi-tissue comprised of neurons, dendrites, axon terminals, glial cells, and capillaries.[TAO] AEO:0001012 EHDAA2:0003136 EHDAA2_RETIRED:0004658 EMAPA:37596 FMA:67242 HBA:4006 MA:0001112 NCIT:C32695 OpenCyc:Mx4rwDdKMpwpEbGdrcN5Y29ycA TAO:0002197 UMLS:C0018220 VHOG:0001768 ZFA:0001681 gray matter gray matter of neuraxis grey matter grey matter of neuraxis grey substance neuronal grey matter substantia grisea uberon gray mater grisea UBERON:0002020 gray matter https://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]. Dorsal part of the hindbrain that coordinates muscle movement, posture, and balance.[AAO] Specialized brain region derived from the dorsal metencephalon (anterior hindbrain, and perhaps including posterior midbrain) and becoming distinctive late in the segmentation period. Kimmel et al, 1995.[TAO] However, although the lamprey possesses a region comparable to the cerebellum and display expression of LjFgf8/17 at the MHB (midbrain hindbrain boundary), it does not have Purkinje cells and cerebellar nuclei, as well as components of the rhombic lip-derived cerebellar and pre-cerebellar systems. It is noteworthy that the latter structures require specific expression of Pax6 in the rhombic lip of the gnathostome hindbrain. Interestingly, the lamprey rhombic lip does not express Pax6. Thus, it is tempting to speculate that in vertebrate evolution the rostral hindbrain is incapable of differentiating into the cerebellum before the co-option of Pax6 in that region. In other words, cerebellum has been brought about as an evolutionary innovation in gnathostomes, based on exaptation of MHB, rhombic lip, and some regulatory gene expression already present in the vertebrate common ancestor.[well established][VHOG] cerebellar The absence of a cerebellum in hagfishes and lampreys appears to be the only exception [to the rule that vertebrates possess the same number of brain divisions]. Both hagfishes and lampreys do possess a thin band of cells located medial to the lateral line centers of the medulla (Ronan and Northcutt, 1998), which has been interpreted as a primitive cerebellum (Larsell, 1967), but more recent experimental studies (Kishida et al., 1987; Weigle and Northcutt, 1998) fail to support Larsell's claim[http://icb.oxfordjournals.org/content/42/4/743.full] almost all AOs agree that the cerebellum is part of the hindbrain (sometimes specifically part of the metencephalon, which, when present, is part of the hindbrain). However, ABA has cerebellum and brain stem as partof siblings, with the hindbrain part of the brainstem infratentorial region AAO:0010485 BAMS:CB BAMS:Cb BIRNLEX:1489 BM:CB BTO:0000232 CALOHA:TS-0125 DHBA:10656 EFO:0000327 EHDAA2:0000232 EMAPA:17787 EV:0100293 FMA:67944 GAID:595 HBA:4696 MA:0000198 MAT:0000110 MBA:512 MESH:D002531 MIAA:0000110 NCIT:C12445 OpenCyc:Mx4rvl1eipwpEbGdrcN5Y29ycA TAO:0000100 UMLS:C0007765 UMLS:C1268981 VHOG:0000024 XAO:0003098 ZFA:0000100 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=643 epencephalon-1 uberon corpus cerebelli parencephalon UBERON:0002037 cerebellum https://upload.wikimedia.org/wikipedia/commons/a/a7/Cerebellum_NIH.png Predominantly gray matter midbrain structure lying dorsal to the crus cerebri and ventral to the midbrain tegmentum. It is divided into a dorsal, cellularly compact region known as the pars compacta and a more ventrally located, containing more loosely packed cells, the pars reticulata. The most lateral region of the reticulata is identified as the pars lateralis (MM). TODO - In BTO and NIF, part of basal ganglion which is part of telencephalon - but this is inconsistent with being part of midbrain, if these are spatially disjoint, as in ABA Subdivision of the midbrain anterior to the midbrain tegmentum which contains darkly pigmented neurons[FMA][FMA:67947]. (...) the substantia nigra first appears in reptiles and is best developed in primates.[well established][VHOG] SN BAMS:SN BIRNLEX:789 BTO:0000143 CALOHA:TS-0990 DHBA:12251 EFO:0000922 EHDAA2:0004711 EMAPA:35835 EV:0100247 FMA:67947 GAID:581 HBA:9072 MA:0000210 MAT:0000504 MESH:A08.186.211.132.659.687 NCIT:C12453 UMLS:C0038590 UMLS:C1269578 VHOG:0001573 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=536 Soemmering's substance nucleus of basis pedunculi uberon nucleus pigmentosus subthalamo-peduncularis substancia nigra substantia nigra (Soemmerringi) UBERON:0002038 substantia nigra http://upload.wikimedia.org/wikipedia/commons/5/5f/Midbraincrosssection.png The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]. TODO - check ZFA/pons. also GO says part of dorsorostral pons BAMS:CAE BAMS:LC BIRNLEX:905 BM:Pons-LC BTO:0001408 DHBA:12819 DMBA:16972 EFO:0001963 EMAPA:35502 FMA:72478 GAID:577 HBA:9148 MA:0001017 MBA:147 MESH:D008125 NCIT:C97333 TAO:0000539 UMLS:C0023951 ZFA:0000539 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=583 blue nucleus caerulean nucleus locus caeruleus locus coeruleu locus coeruleus nucleus caeruleus nucleus of locus caeruleus nucleus pigmentosus pontis substantia ferruginea uberon loci coeruleus locus cinereus locus coeruleus (Vicq d'Azyr) nucleus loci caerulei UBERON:0002148 locus ceruleus http://upload.wikimedia.org/wikipedia/commons/7/77/Gray709.png Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). TODO - add superclass to unify with VNC? Part of the central nervous system which descends from the hindbrain within the vertebral column.[AAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG] AAO:0010151 BAMS:SP BAMS:Spinal BIRNLEX:1709 BM:SpC BTO:0001279 CALOHA:TS-0953 DHBA:12890 DMBA:17651 EFO:0000110 EHDAA2:0001255 EHDAA:2863 EMAPA:17577 EV:0100316 FMA:7647 GAID:695 MA:0000216 MAT:0000183 MESH:D013116 MIAA:0000183 NCIT:C12464 OpenCyc:Mx4rvVjjk5wpEbGdrcN5Y29ycA TAO:0000075 UMLS:C0037925 VHOG:0000601 XAO:0000020 ZFA:0000075 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=22 uberon SpC cerebro-cerebellar fissure cerebrocerebellar fissure fissura cerebro-cerebellaris fissura cerebrocerebellaris medulla spinalis spinal cord structure spinal medulla UBERON:0002240 spinal cord http://upload.wikimedia.org/wikipedia/commons/5/58/Spinal_cord_direv.svg Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]. Multi-tissue structure that has as its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain.[TAO] Multi-tissue structure that has as its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,adopted][ZFA:0001707]. the stalk-like part of the brain that comprises the midbrain (aka mesencephalon), the pons (aka pons Varolii), and the medulla oblongata, and connects the cerebral hemispheres with the cervical spinal cord[MP] BAMS:BS BIRNLEX:1565 BTO:0000146 CALOHA:TS-0093 EFO:0001962 EMAPA:32678 EV:0100241 FMA:79876 MA:0000169 MBA:343 MESH:D001933 NCIT:C12441 TAO:0002156 UMLS:C0006121 VHOG:0001457 ZFA:0001707 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=236 brain stem truncus encephali uberon accessory medullary lamina of pallidum lamella pallidi incompleta lamina medullaris accessoria lamina medullaris incompleta pallidi lamina pallidi incompleta truncus encephalicus UBERON:0002298 'brainstem' is a loose term that sometimes refers to the ventral parts o the brain except for any part of the telencephalon - sometimes it includes the diencephalon or subpallial telencephalon structures (ISBN:0471888893). Here we use it in a more restriced sense, to include only the medulla oblongata, pons (when present) and the midbrain tegmentum (following the ZFA definitions). brainstem http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray719.png One of the three layers of the dentate gyrus of the hippocampal formation. the basic trilaminar structure of the dentate gyrus is common across all species studied, with relatively minimal phylogenetic variation[PMC2492885] EMAPA:35278 FMA:83678 MA:0002429 dentate gyrus cell layer dentate gyrus layer uberon UBERON:0002304 layer of dentate gyrus A neural nucleus that is part of the brain. EMAPA:35185 FMA:83840 MA:0000811 NCIT:C49346 UMLS:C1706993 ZFA:0005575 brain nucleus uberon brain nuclei UBERON:0002308 nucleus of brain Neural tissue consisting of myelinated axons connecting grey matter areas of the central nervous system. Cell part cluster consisting predominantly of neurites in the brain and the spinal cord[FMA:83929]. Multi-tissue structure comprised largely of myelinated axons.[TAO] The myelination of axons by glial cells was the last major step in the evolution of cells in the vertebrate nervous system, and white-matter tracts are key to the architecture of the mammalian brain.[well established][VHOG] nlx_anat_101177 seems to have been lost in the transition from NIFGA to Neurolex AEO:0000139 AEO:0001011 EMAPA:35927 FMA:83929 HBA:9218 MA:0001135 NCIT:C33892 NLX:412 NLXANAT:101177 OpenCyc:Mx4rwOAsDZwpEbGdrcN5Y29ycA PBA:294022044 TAO:0000145 TAO:0002142 TAO:0002143 UMLS:C0682708 VHOG:0001764 ZFA:0001682 CNS tract/commissure neuronal white matter white matter of neuraxis white substance uberon CNS tracts and commissures CNS white matter substantia alba white mater UBERON:0002316 white matter An individual member of a collection of basal ganglia. Basal ganglia are subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum[NIF,modified]. it is necessary to introduce two classes, one representing an individual basal ganglion, another representing the aggregate structure, in order to have consistent classification amongst AOs (e.g. in MA the aygdala is part of the BG, in FMA and BTO it is a subclass). Apart from achieving this consistency, the value of having two distinct classes is questionable, since the BG-plural is trivially the set of all BGs-singular. it would be better for all AOs to decide on one single way of doing this. Do not merge until this is done. BTO:0000235 CALOHA:TS-1149 DHBA:10332 EFO:0000904 FMA:62514 basal ganglion of telencephalon uberon basal ganglia basal nucleus nuclei basales UBERON:0002420 basal ganglion http://upload.wikimedia.org/wikipedia/commons/1/1b/Basal_Ganglia_and_Related_Structures.svg Hippocampus (proper) plus dentate gyrus and subiculum[definition derived from NIF comments and ontology alignment]. The term hippocampus is often used synonymously with hippocampal formation which consists of the hippocampus proper or Cornu Ammonis, the dentate gyrus and the subiculum BTO:0000601 is placed here since it includes the DG. GO also includes dentate gyrus development as part of hippocampus development, so we assume when GO says 'hippocampus' it means 'hippocampal formation'. In ABA HPF = (.. subiculum) + HIP, HIP = DG + AH. BAMS:HPF BAMS:Hi BAMS:HiF BIRNLEX:715 BM:Tel-HF BTO:0000601 DHBA:10294 EMAPA:35405 FMA:74038 HBA:4249 MA:0000189 MBA:1089 PBA:4003 UMLS:C0175202 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=177 hippocampus (Crosby) hippocampus uberon archipallium formatio hippocampi major hippocampus primal cortex seahorse UBERON:0002421 hippocampal formation A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.[GO]. striatal FMA divides 'striatum of neuraxis' into 4, neostriatum is seperate class. In NIF these are synonyms. TODO - check striatum vs corpus striatum see Wikipedia:Striatum#History. Check caudoputamen BAMS:STR BAMS:Str BAMS:Striatum BIRNLEX:1672 BM:N BTO:0000418 DHBA:10333 DMBA:15851 EFO:0000109 EMAPA:17549 FMA:77618 FMA:83683 HBA:4277 MA:0000891 MBA:477 MESH:A08.186.211.730.885.105.487.550 NCIT:C111122 PBA:10080 UMLS:C0162512 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=225 ncithesaurus:Striatum neostriatum neuraxis striatum striate nucleus striatum striatum of neuraxis uberon caudate putamen corpus striatum corpus striatum (Zilles) dorsal striatum striated nucleus UBERON:0002435 striatum http://upload.wikimedia.org/wikipedia/commons/3/33/BrainCaudatePutamen.svg Part of cerebral hemisphere located on the medial surface, forming a ring around the brain stem. BAMS:LL BAMS:Limbic_lobe BIRNLEX:1128 CALOHA:TS-2061 DHBA:12155 FMA:72719 HBA:4219 UMLS:C0458337 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=834 fornicate gyrus grande lobe limbique of Broca limbic lobe (carpenter) uberon fornicate convolution fornicate lobe gyrus fornicatus lobus limbicus UBERON:0002600 limbic lobe http://upload.wikimedia.org/wikipedia/commons/7/7e/Human_brain_inferior-medial_view_description.JPG Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia. BIRNLEX:1167 FMA:55676 NCIT:C13031 UMLS:C0445620 anatomical structure of brain biological structure of brain brain anatomical structure brain biological structure brain part neuraxis segment neuroanatomical region segment of brain uberon UBERON:0002616 regional part of brain Component of the temporal lobe on the mesial surface. The rostral and caudal boundaries of the entorhinal cortex are the rostral end of the collateral sulcus and the caudal end of the amygdala respectively. The medial boundary is the medial aspect of the temporal lobe and the lateral boundary is the collateral sulcus. (DK). TODO - check area vs complex. MBA:909 this is part of the hippocampal formation via retrohippocampal region In primates it is found on the medial surface of the temporal lobe, partially bounded ventrolaterally by the collateral sulcus in the human and by the rhinal sulcus in the macaque. It is subdivided on the basis of internal structure into eight parts in the human ( Insausti-2004 ),and seven parts in the macaque ( Paxinos-2009a ). In the rat and mouse it is divided into a lateral part of the entorhinal area and a medial part of the entorhinal area; the latter is further divided into dorsal and ventral zones to produce three subdivisions in the rodent ( Swanson-2004 ) BAMS:ENT BAMS:Ent BIRNLEX:1508 BM:Tel-Cx-ENT BTO:0002650 DHBA:10317 DMBA:16102 EFO:0001920 EMAPA:35313 FMA:72356 GAID:636 MA:0003117 MBA:909 MESH:A08.186.211.577.710.225 NCIT:C97338 PBA:294022158 UMLS:C0175196 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=168 entorhinal area uberon Brodmann's area 28 area entorhinalis (28,34) area entorhinalis ventralis et dorsalis cortex entorhinalis entorhinal cortex UBERON:0002728 entorhinal cortex http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray-Brodman-Entorhinal_Cortex_EC_.png Component of the temporal lobe, lateral aspect. The rostral boundary is the rostral extent of the inferior temporal sulcus whereas the caudal boundary is designated as the temporo-occipital incisure on the cortical surface. The occipitotemporal sulcus is the medial boundary and the inferior temporal sulcus is the lateral boundary (Christine Fennema-Notestine). BAMS:ITG BIRNLEX:1577 BM:Tel-ITG DHBA:12142 FMA:61907 HBA:4147 NCIT:C32791 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=138 ncithesaurus:Inferior_Temporal_Gyrus gyrus temporalis inferior lateral occipitotemporal gyrus (heimer-83) uberon IT cortex gyrus temporalis inferior inferotemporal cortex UBERON:0002751 inferior temporal gyrus http://upload.wikimedia.org/wikipedia/commons/3/35/Gray726.png The cingulate cortex is a part of the brain situated in the medial aspect of the cortex. It is extended from the corpus callosum below to the cingulate sulcus above, at least anteriorly. [WP,unvetted]. BIRNLEX:934 BM:Tel-Cx-Cg BTO:0003975 DHBA:10277 DMBA:16072 EFO:0000343 EMAPA:35242 MA:0000904 NCIT:C52713 UMLS:C0598179 cingulate neocortex uberon gyrus cingulatus gyrus cinguli UBERON:0003027 cingulate cortex http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray727_cingulate_gyrus.png Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. this class was introduced for consistency with CARO. However, in this ontology we typically classify organs directly under 'organ' rather than subdividing into compound and simple organs AAO:0010015 AEO:0000024 BILA:0000024 CARO:0000024 EHDAA2:0003024 HAO:0000024 TADS:0000598 TAO:0000496 TGMA:0001837 VHOG:0001723 XAO:0003041 ZFA:0000496 uberon organ UBERON:0003103 compound organ A gray matter that is part of a brain [Automatically generated definition]. EMAPA:35184 MA:0000810 NCIT:C49333 UMLS:C1707348 brain grey matter brain grey substance gray matter of brain grey matter of brain grey substance of brain uberon UBERON:0003528 brain gray matter a part or parts of the hippocampus that have a particular function do not include ABA:HIP BAMS:HIP BAMS:Hi/CA EMAPA:32772 FMA:74041 MA:0002428 hippocampus subdivision subdivision of hippocampus uberon hippocampal region hippocampus region UBERON:0003876 hippocampal field small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]. Fenestrated blood vessel endothelium with pores that are large enough for blood cells to pass. The basal lamina and gap junctions may be discontinuous.[TAO] sinusoidal some sources give discontinuous capillary as synonym but this may be a subtype - see FMA:63198 discontinuous sinusoid (undefined). FMA:63131 TAO:0005261 ZFA:0005261 sinusoidal blood vessel sinusoidal blood vessel endothelium uberon endothelium of irregular blood filled space sinusoidal capillary sinusoidal endothelium UBERON:0003909 sinusoid The brain ventricles or their associated choroid plexuses TODO - check relationship between CP and BV. If this is part of then this class should be obsoleted TODO merge into BV uberon UBERON:0003947 brain ventricle/choroid plexus one of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that like it are derived from the medullary canal of the embryo, that are lined with an epithelial ependyma, and that contain a serous fluid Organ cavity of the brain which consists of the lateral ventricles, the third and fourth ventricles and the cerebral aqueduct[BIRNLEX:1356]. FMA draws the distinction between e.g. 'fourth ventricle' and 'cavity of fourth ventricle'. The latter is a cavity, and part of the former, which is a region. The superclass of 'fourth ventricle' is_a 'region of ventricular system of the brain'. We place this class here, although it is not equivalent to ventricles, as it includes ventricle bodies. BIRNLEX:1356 BTO:0001442 EFO:0001914 EMAPA:32674 FMA:78447 HBA:9418 MA:0000818 MESH:D002552 NCIT:C12356 OpenCyc:Mx4rvmTY65wpEbGdrcN5Y29ycA UMLS:C0007799 brain ventricles cerebral ventricle region of ventricular system of brain uberon UBERON:0004086 brain ventricle An anatomical structure that develops (entirely or partially) from the mesoderm. Grouping term for query purposes FBbt:00025998 mesodermal derivative uberon UBERON:0004120 mesoderm-derived structure An anatomical structure that develops (entirely or partially) from the ectoderm. Grouping term for query purposes FBbt:00025990 ectodermal deriviative uberon UBERON:0004121 ectoderm-derived structure A part of a wall of an organ that forms a layer. FMA:82485 uberon UBERON:0004923 organ component layer A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part. we go with the FMA classification rather than the CARO one. FMA def: 'Anatomical cluster which has as direct parts cell parts from two or more cells.' AAO:0011000 CARO:0001000 FBbt:00007060 FMA:83115 multi-cell-component structure multi-cell-part structure uberon cell part cluster UBERON:0005162 multi cell part structure An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back. EMAPA:37274 MA:0001901 back organ dorsal region organ uberon UBERON:0005174 dorsal region element A layer in the central nervous system that lines system of communicating cavities in the brain and spinal cord. EMAPA:35209 FMA:242770 ventricular layer uberon region of wall of ventricular system of neuraxis UBERON:0005358 ventricle of nervous system A gray matter that is part of a cerebral hemisphere. BTO may actually be a more generic structure; FMA may represent a more specific structure. Consider merging with gray matter of telencephalon BTO:0000823 CALOHA:TS-2361 EMAPA:37477 FMA:61821 MA:0000944 cerebral gray matter cerebral grey matter cerebral hemisphere grey matter uberon UBERON:0005401 cerebral hemisphere gray matter FMA:10483 bone organ zone uberon UBERON:0005913 zone of bone organ Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. fluid BIRNLEX:20 EMAPA:37441 FMA:280556 GAID:266 MESH:D001826 galen:BodyFluid body fluid uberon UBERON:0006314 bodily fluid A nucleus of brain that is part of a brainstem. EMAPA:32790 MA:0000821 uberon brain stem nucleus UBERON:0006331 brainstem nucleus An epithelium characterised by its most superficial layer consisting of squamous epithelial cells. FBbt:00007028 (squamous epithelium) A type of epithelium that is made up of flattened cells which are arranged with their long axes in the plane of the epithelium BTO:0002072 NCIT:C12848 UMLS:C0221909 uberon UBERON:0006914 squamous epithelium Gray matter of the central nervous system which is a collection of clustered nuclei. FMA:256381 FMA:84059 uberon cluster of neural nuclei neural nuclei nuclear complex UBERON:0007245 nuclear complex of neuraxis Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces. transudative characteristically low in protein and cellular content (unless there has been secondary concentration) FMA:12276 GAID:1195 MESH:D005122 ncithesaurus:Transudate uberon plasma ultrafiltrate UBERON:0007779 transudate Nucleus located in the midbrain. TAO:0002209 ZFA:0001665 uberon UBERON:0009661 midbrain nucleus Nucleus located within the hindbrain. TAO:0002177 ZFA:0001658 uberon UBERON:0009662 hindbrain nucleus The dorsolateral prefrontal cortex (DL-PFC or DLPFC), according to a more restricted definition, is roughly equivalent to Brodmann areas 9 and 46.[1] According to a broader definition DL-PFC consists of the lateral portions of Brodmann areas 9 - 12, of areas 45, 46, and the superior part of area 47.[2] These regions mainly receive their blood supply from the middle cerebral artery. With respect to neurotransmitter systems, there is evidence that dopamine plays a particularly important role in DL-PFC.[2]DL-PFC is connected to the orbitofrontal cortex, and to a variety of brain areas, which include the thalamus, parts of the basal ganglia (the dorsal caudate nucleus), the hippocampus, and primary and secondary association areas of neocortex, including posterior temporal, parietal, and occipital areas. check dorsolateral prefrontal neocortex DHBA:10173 FMA:276189 uberon UBERON:0009834 dorsolateral prefrontal cortex The frontal part of the cingulate cortex that resembles a collar form around the corpus callosum. It includes both the ventral and dorsal areas of the cingulate cortex. Wikipedia:File:Gray727.svg. BIRNLEX:936 BTO:0004249 FMA:271599 uberon ACC UBERON:0009835 anterior cingulate cortex http://upload.wikimedia.org/wikipedia/commons/2/22/Gray727_anterior_cingulate_cortex.png An anatomical structure that has more than one cell as a part. CARO:0010000 FBbt:00100313 multicellular structure uberon UBERON:0010000 multicellular anatomical structure A small cluster of cells of various types which form a discrete structure, largely delimited by a morphological boundary and whose components work together to make the whole structure capable of a specific function. CARO:0010001 FBbt:00007229 uberon UBERON:0010001 Examples include arthropod sensilla. cell cluster organ An anatomical structure that has some part that develops from the neural crest. Grouping term for query purposes uberon UBERON:0010314 structure with developmental contribution from neural crest A multi cell part structure that is part of a central nervous system. FMA:83143 cell part cluster of neuraxis neuraxis layer uberon UBERON:0011215 central nervous system cell part cluster A subdivision of an anatomical system. FBbt:00007330 FMA:67509 uberon UBERON:0011216 organ system subdivision A portion of gray matter that is part of a telencephalon. UBERON:0024186 BIRNLEX:1067 FMA:83911 predominantly gray regional part of telencephalon uberon UBERON:0011300 gray matter of telencephalon Epithelium that derives from the mesoderm. [Automatically generated definition]. FMA:86452 mesoderm-derived epithelium mesoepithelium uberon UBERON:0012275 meso-epithelium A segmentation of the cerebral cortex on the basis of cytoarchitecture as described in Brodmann-1905, Brodmann-1909 and Brodmann-10. Maps for several species were presented. NeuroNames includes only areas in the human and in Old World monkeys. Of the latter, Brodmann studied representatives of several species including guenons (one Cercopithecus mona, one Cercocebus torquatus, and one Cercopithecus otherwise unspecified), which are all closely related African species, and one macaque (Macaca mulatta) an Asian species (Brodmann-1905). The legend to the summary map in Brodmann-1909 ascribes the areas simply to Cercopithecus. Brodmann referenced the areas by name and number. The same area number in humans and monkeys did not necessarily refer to topologically or cytoarchitecturally homologous structures. In NeuroNames the standard term for human areas consists of the English translation of Brodmann's Latin name followed by the number he assigned, e.g., agranular frontal area 6; the standard terms for monkey areas are in the format: area 6 of Brodmann-1909. He mapped a portion of areas limited to the banks of sulci, e.g., area 3 of Brodmann-1909 (Brodmann-1909) onto the adjacent, visible surface. This accounts for the fact that some areas appear larger on his surface map than on maps of other authors, e.g., area 3 of Vogts-1919. (Adapted from NeuroNames) BAMS:VTM BIRNLEX:1731 FMA:68596 NCIT:C94868 WikipediaCategory:Brodmann_areas http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=1032 uberon Brodmann parcellation scheme region Brodmann partition scheme region Brodmann's areas UBERON:0013529 Brodmann area periventricular grey matter uberon UBERON:0014933 periventricular gray matter Any structure that is placed on one side of the left-right axis of a bilaterian. This class is primarily to implement taxon constraints. It may be removed in the future. uberon UBERON:0015212 lateral structure Frontal lobe is the anterior-most of five lobes of the cerebral hemisphere. It is bounded by the central sulcus on its posterior border and by the longitudinal cerebral fissure on its medial border. Many species don't have lobes but they do have frontal cortex. Lobe isn't a really well defined term though frontal region regio frontalis BAMS:Frontal_lobe BIRNLEX:928 BM:Tel-Cx-FR CALOHA:TS-0389 DHBA:12113 EFO:0000913 EV:0100167 FMA:61824 HBA:4009 MAT:0000505 MESH:A08.186.211.730.885.213.270 NCIT:C12352 OpenCyc:Mx4rv3OJ8JwpEbGdrcN5Y29ycA UMLS:C0016733 UMLS:C1268977 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=56 lobi frontales lobus frontalis frontal cortex uberon UBERON:0016525 frontal lobe Subdivision of telencephalon which is one of a number of subdivisions of each hemisphere separated by both real landmarks (sulci and fissures) and arbitrary boundaries[FMA,modified]. UBERON:0000322 BIRNLEX:922 BTO:0000445 FMA:61823 cerebral hemisphere lobe cerebral lobe lobe of cerebral cortex lobe parts of cerebral cortex lobi cerebri uberon cerebral cortical segment lobes of the brain regional organ part of cerebral cortex segment of cerebral cortex UBERON:0016526 We use the term lobe broadly as a rough regional area, encompassing homologous regions in smooth-brained mammals. We subdivide the lobes into white matter and neocortical parts. lobe of cerebral hemisphere Grey matter neocortex region of a lobe of the cerebral hemisphere. FMA:242197 cortex of cerebral hemisphere lobe cortex of lobe of cerebral hemisphere uberon gray matter of lobe of cerebral hemisphere neocortical part of cerebral hemisphere UBERON:0016529 cortex of cerebral lobe DHBA:10268 DMBA:16030 EMAPA:35604 FMA:242205 MA:0000913 PBA:4004 cortex of occipital lobe occipital lobe cortex occipital neocortex uberon gray matter of occipital lobe UBERON:0016540 occipital cortex A layer of of the central nervous system that is part of gray matter. grey matter layer FMA:83142 CNS gray matter layer CNS grey matter layer gray matter layer of neuraxis grey matter layer of neuraxis uberon UBERON:0016548 central nervous system gray matter layer DHBA:10157 FMA:268608 uberon UBERON:0019264 gray matter of forebrain Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]. this is currently used to group some cellular layers that may not strictly conform to the CARO definition of cell-part layer. Consider genericisizing and introducing subtypes for cellular layer, fibrous layer and cell soma layer lamina layer NLX:149357 uberon UBERON:0022303 nervous system cell part layer Component of the cingulate cortex. The rostral and caudal extent were the caudal anterior and the isthmus divisions of the cingulate cortex respectively. The medial and lateral boundaries were the corpus callosum and as the superior frontal gyrus and/or paracentral lobule respectively (Christine Fennema-Notestine). check relationship to gyrus. See https://github.com/obophenotype/uberon/issues/626 posterior cingulate BIRNLEX:950 BTO:0004250 EFO:0002471 FMA:271593 uberon cingulate gyrus, posterior division posterior cingular cortex UBERON:0022353 posterior cingulate cortex A part of an organism or organ that is continuous with its surroundings and distinguished from its surroundings based on morphology. uberon UBERON:0034768 morphological feature A cluster of cells, largely surrounded by a morphological boundary. CARO:0020002 FMA:62807 uberon UBERON:0034922 cell cluster FMA:55268 organ sector organ zonal region organ zone uberon organ region with floating fiat boundary UBERON:0034944 zone of organ A brain region defined by functional criteria, e.g. auditory cortex, rather than by structural or histological criteria. NLX:155513 uberon UBERON:0035014 functional part of brain This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon ZFA:0001710 uberon UBERON:2002210 mossy fiber This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon ZFA:0001713 parallel fibers uberon UBERON:2002218 parallel fiber The totality of the chemical reactions and physical changes that occur in living organisms, comprising anabolism and catabolism; may be qualified to mean the chemical reactions and physical processes undergone by a particular substance, or class of substances, in a living organism. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. GO:0008152 pathway UPa:UPA00026 metabolism The chemical reactions involved in energy transformations within cells. . GO:0006091 GO:0006112 pathway UPa:UPA00426 energy metabolism Degradation of cellular proteins. GO:0044257 pathway proteolysis UPa:UPA00468 protein degradation CHEBI:18035 KEGG:C00165 compound UPa:UPC00165 diacylglycerol CHEBI:16057 KEGG:C00235 compound C5H12O7P2 InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h3H,4H2,1-2H3,(H,9,10)(H2,6,7,8) dimethylallyl-PP UPa:UPC00235 dimethylallyl diphosphate CHEBI:15372 CHEBI:59560 KEGG:C00272 compound C9H15N5O3 InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,4+,6-/m0/s1 UPa:UPC00272 tetrahydrobiopterin YH mouse gene Any condition in which the main influencing factor is an agent that blocks the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. slaulede 2019-12-16T17:38:36Z experimental_condition_ontology XCO:0000653 ionotropic glutamate receptor antagonist true performing physical activity true non-pharmacotherapy procedure A molecule on the surface or within a cell that recognizes and binds with specific molecules, producing a specific effect in the cell. IDOMAL:0000373 2009-11-22T06:45:49Z receptor IDOMAL:0000373 guest idomal_namespace idomal_namespace C3b is the principal protein fragment produced when complement component C3 is cleaved by convertases of either the classical or alternative pathway. C3b aids in opsonization. guest IDOMAL:0000581 C3b complement component 3b IDOMAL:0000581 2009-11-23T02:17:58Z